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Publications:  Dr Jesmond Dalli

Plebani R, Colas RA, Mattoscio D, Trerotola M, Gomez EA, Isopi E, Castagnozzi S, Dalli J et al. (2020). CFTR ABLATION BY CRISPR/CAS9 IMPAIRS THE PRODUCTION OF PRO-RESOLVING LIPID MEDIATORS BY HUMAN AIRWAY EPITHELIAL CELLS. PEDIATRIC PULMONOLOGY. vol. 55, S75-S75.
Schaller MS, Chen M, Colas RA, Sorrentino TA, Lazar AA, Grenon SM, Dalli J, Conte MS(2020). Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease. Journal of the American Heart Association vol. 9, (15)
10.1161/JAHA.120.016113
Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J et al.(2020). ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1865, (7)
10.1016/j.bbalip.2020.158679
Allen BL, Montague-Cardoso K, Simeoli R, Colas RA, Oggero S, Vilar B, McNaughton PA, Dalli J et al.(2020). Imbalance of pro-resolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis. Pain
10.1097/j.pain.0000000000001908
Fussbroich D, Colas RA, Eickmeier O, Trischler J, Jerkic SP, Zimmermann K, Göpel A, Schwenger T et al.(2020). A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA. Mucosal Immunology vol. 13, (3) 481-492.
10.1038/s41385-019-0245-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64353
Becares N, Härmälä S, China L, Colas RA, Maini AA, Bennet K, Skene SS, Shabir Z et al.(2020). Immune Regulatory Mediators in Plasma from Patients With Acute Decompensation Are Associated With 3-Month Mortality. Clinical Gastroenterology and Hepatology vol. 18, (5) 1207-1215.e6.
10.1016/j.cgh.2019.08.036
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62390
Shivakoti R, Dalli J, Kadam D, Gaikwad S, Barthwal M, Colas RA, Mazzacuva F, Lokhande R et al.(2020). Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes. Prostaglandins Other Lipid Mediat vol. 147,
10.1016/j.prostaglandins.2019.106398
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63799
Pangopoulos MK, Nolsøe JMN, Antonsen SG, Colas RA, Dalli J, Aursnes M, Stenstrøm Y, Hansen TV(2020). Enzymatic studies with 3-oxa n-3 DPA. Bioorganic Chemistry vol. 96,
10.1016/j.bioorg.2020.103653
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64754
Määttänen P, Lurz E, Botts SR, Wu RY, Robinson SC, Yeung CW, Colas R, Li B et al.(2020). Plant- and Fish-Derived n-3 PUFAs Suppress Citrobacter Rodentium–Induced Colonic Inflammation. Molecular Nutrition and Food Research vol. 64, (6)
10.1002/mnfr.201900873
Wilcz-Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R et al.(2020). Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway. EMBO Molecular Medicine vol. 12, (2)
10.15252/emmm.201910491
https://qmro.qmul.ac.uk/xmlui/handle/123456789/66386
Flak MB, Koenis DS, Sobrino A, Smith J, Pistorius K, Palmas F, Dalli J(2020). GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections. Journal of Clinical Investigation vol. 130, (1) 359-373.
10.1172/JCI131609
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63972
Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV et al.(2020). A single injection of docosahexaenoic acid induces a pro-resolving lipid mediator profile in the injured tissue and a long-lasting reduction in neurological deficit after traumatic brain injury in mice. Journal of Neurotrauma vol. 37, (1) 66-79.
10.1089/neu.2019.6420
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59204
Souza PR, Marques RM, Gomez EA, Colas RA, De Matteis R, Zak A, Patel M, Collier DJ et al.(2019). Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses: A Randomized Double-Blind Placebo-Controlled Study. Circ Res
10.1161/CIRCRESAHA.119.315506
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63722
Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C et al.(2019). Proresolving Mediators LXB4 and RvE1 Regulate Inflammation in Stromal Cells from Patients with Shoulder Tendon Tears. American Journal of Pathology vol. 189, (11) 2258-2268.
10.1016/j.ajpath.2019.07.011
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60703
Colas RA, Nhat LTH, Thuong NTT, Gómez EA, Ly L, Thanh HH, Mai NTH, Phu NH et al.(2019). Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 33, (11) 13028-13039.
10.1096/fj.201901590R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62180
Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R et al.(2019). Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1864, (10) 1350-1362.
10.1016/j.bbalip.2019.06.010
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62004
Nesman JI, Primdahl KG, Tungen JE, Palmas F, Dalli J, Hansen TV(2019). Synthesis, structural confirmation, and biosynthesis of 22-OH-PD1<inf>n-3 DPA</inf><sup>†</sup>. Molecules vol. 24, (18)
10.3390/molecules24183228
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61514
Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE et al.(2019). Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction. EBioMedicine vol. 46, 264-273.
10.1016/j.ebiom.2019.07.024
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59336
Valkonen S, Holopainen M, Colas RA, Impola U, Dalli J, Käkelä R, Siljander PRM, Laitinen S(2019). Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1864, (8) 1168-1182.
10.1016/j.bbalip.2019.03.011
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61880
Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al. (2019). Proresolving mediators counter inflammation in stromal cells from patients with Achilles tendon disease. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 100, A15-A15.
Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J, Pitzalis C(2019). Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis. JCI Insight vol. 4, (13)
10.1172/jci.insight.125191
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59622
Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al.(2019). 15-Epi-LXA<inf>4</inf> and MaR1 counter inflammation in stromal cells from patients with Achilles tendinopathy and rupture. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 33, (7) 8043-8054.
10.1096/fj.201900196R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58279
Colas RA, Thwaites GE, Thuong NT, Ly L, Phu NH, Ramakrishnan L, Mai NT, Dalli J (2019). Pro-resolving mediator profiles and 5-lipoxygenase activity in cerebrospinal fluids correlate with disease severity and outcomes in adults with tuberculosis meningitis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 85, 1639-1639.
Dakin SG, Colas RA, Dean BJF, Wheway K, Watkins B, Dalli J, Carr AJ(2019). Tendon cells isolated from patients with persistent shoulder tendinopathy show dysregulated resolution responses. Translational Sports Medicine vol. 2, (4) 173-176.
10.1002/tsm2.86
Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J et al.(2019). Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock. Ann Surg
10.1097/SLA.0000000000003407
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59582
López-Vicario C, Titos E, Walker ME, Alcaraz-Quiles J, Casulleras M, Durán-Güell M, Flores-Costa R, Pérez-Romero N et al.(2019). Leukocytes from obese individuals exhibit an impaired SPM signature. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 33, (6) 7072-7083.
10.1096/fj.201802587R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58599
Becares N, Maini AA, Colas RA, Dalli J, Gilroy DW, O¿brien A (2019). FRI-109-Increased plasma leukotriene B4 in decompensated cirrhosis associates with disease progression and leads to increased skin window neutrophil infiltration. Journal of Hepatology. vol. 70,
10.1016/s0618-8278(19)30854-0
Dalli J, Serhan CN(2019). Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology. Br J Pharmacol vol. 176, (8) 1024-1037.
10.1111/bph.14336
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38783
Dalli J, Pistorius K, Walker ME(2019). Novel n-3 Docosapentaneoic Acid-Derived Pro-resolving Mediators Are Vasculoprotective and Mediate the Actions of Statins in Controlling Inflammation. Advances in Experimental Medicine and Biology vol. 1161, 65-75.
10.1007/978-3-030-21735-8_7
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62767
Sønderskov J, Tungen JE, Palmas F, Dalli J, Serhan CN, Stenstrøm Y, Vidar Hansen T(2019). Stereoselective synthesis of MaR2<inf>n-3 DPA</inf>. Tetrahedron Letters
10.1016/j.tetlet.2019.151510
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62903
Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN et al.(2018). Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA. Chemistry vol. 25, (6) 1476-1480.
10.1002/chem.201806029
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55105
Serhan CN, Chiang N, Dalli J(2018). New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration. Mol Aspects Med vol. 64, 1-17.
10.1016/j.mam.2017.08.002
Laguna-Fernandez A, Checa A, Carracedo M, Artiach G, Petri MH, Baumgartner R, Forteza MJ, Jiang X et al.(2018). ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages. Circulation vol. 138, (16) 1693-1705.
10.1161/CIRCULATIONAHA.117.032801
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49416
Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K et al.(2018). n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis. Brain vol. 141, (11) 3130-3143.
10.1093/brain/awy247
https://qmro.qmul.ac.uk/xmlui/handle/123456789/52003
Dalli J, Colas R, de Souza PRS (2018). Impaired Production and Diurnal Regulation of Vascular RvD(n-3) DPA Increases Systemic Inflammation and Cardiovascular Disease. AMERICAN JOURNAL OF PATHOLOGY. vol. 188, 2409-2409.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64961
Chiang N, Riley IR, Dalli J, Rodriguez AR, Spur BW, Serhan CN(2018). New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses. The FASEB Journal vol. 32, (7) 4043-4052.
10.1096/fj.201701493r
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61360
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al.(2018). Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis. FASEB Jfj201701303R-fj201701303R.
10.1096/fj.201701303R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50363
Pistorius K, Souza PR, De Matteis R, Austin-Williams S, Primdahl KG, Vik A, Mazzacuva F, Colas RA et al.(2018). PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function. Cell Chem Biol vol. 25, (6) 749-760.e9.
10.1016/j.chembiol.2018.04.017
https://qmro.qmul.ac.uk/xmlui/handle/123456789/48203
China L, Maini A, Skene SS, Shabir Z, Sylvestre Y, Colas RA, Ly L, Becares Salles N et al.(2018). Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease. Clinical Gastroenterology and Hepatology vol. 16, (5) 738-747.e7.
10.1016/j.cgh.2017.08.027
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49325
Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F et al.(2018). Trypanosoma cruzi produces the specialized proresolving mediators resolvin D1, resolvin D5, and resolvin E2. Infection and Immunity vol. 86, (4)
10.1128/IAI.00688-17
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50043
Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RP, Serhan CN et al.(2018). Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation. JCI insight vol. 3, (6)
10.1172/jci.insight.94463
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45346
Colas RA, Souza PR, Walker ME, Burton M, Zas¿ona Z, Curtis AM, Marques RM, Dalli J(2018). Impaired production and diurnal regulation of vascular RvD <inf>n-3 DPA</inf> increase systemic inflammation and cardiovascular disease. Circulation Research vol. 122, (6) 855-863.
10.1161/CIRCRESAHA.117.312472
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55164
Mai NT, Dobbs N, Phu NH, Colas RA, Thao LT, Thuong NT, Nghia HD, Hanh NH et al.(2018). A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults. eLife vol. 7,
10.7554/eLife.33478
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36601
Dalli J, Serhan CN(2018). Immunoresolvents signaling molecules at intersection between the brain and immune system. Curr Opin Immunol vol. 50, 48-54.
10.1016/j.coi.2017.10.007
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49326
Dalli J, Colas RA, Walker ME, Serhan CN(2018). Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis. Methods Mol Biol vol. 1730, 59-72.
10.1007/978-1-4939-7592-1_4
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56628
Dalli J (2018). Omega-3 Fatty Acids and Resolution of Inflammation. ANNALS OF NUTRITION AND METABOLISM. vol. 73, 190-190.
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al.(2018). Resolvins suppress tumor growth and enhance cancer therapy. Journal of Experimental Medicine vol. 215, (1) 115-140.
10.1084/jem.20170681
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32291
Dalli J(2017). Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections?. Mol Aspects Med vol. 58, 12-20.
10.1016/j.mam.2017.03.007
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23464
Frigerio F, Colas R, Marchini S, van Vliet E, Foerch P, Aronica E, Perretti M, Dalli J et al. (2017). PRORESOLVING ANTIINFLAMMATORY MECHANISMS ARE NOVEL POTENTIAL TARGETS AGAINST EPILEPTOGENESIS. EPILEPSIA. vol. 58, S5-S5.
Dalli J, Serhan CN(2017). Pro-Resolving Mediators in Regulating and Conferring Macrophage Function. Front Immunol vol. 8, 1400-1400.
10.3389/fimmu.2017.01400
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32260
Motwani MP, Newson J, Kwong S, Richard-Loendt A, Colas R, Dalli J, Gilroy DW(2017). Prolonged immune alteration following resolution of acute inflammation in humans. PLoS One vol. 12, (10) Article e0186964, e0186964-e0186964.
10.1371/journal.pone.0186964
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32259
Primdahl KG, Tungen JE, De Souza PRS, Colas RA, Dalli J, Hansen TV, Vik A(2017). Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA. Org Biomol Chem vol. 15, (40) 8606-8613.
10.1039/c7ob02113e
https://qmro.qmul.ac.uk/xmlui/handle/123456789/31204
Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon J-S, Shinohara M et al.(2017). NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4Synthesis. Am J Respir Crit Care Med vol. 196, (6) 713-726.
10.1164/rccm.201604-0892OC
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61757
Dakin SG, Ly L, Colas RA, Oppermann U, Wheway K, Watkins B, Dalli J, Carr AJ(2017). Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy. Sci Rep vol. 7, (1) 11009-11009.
10.1038/s41598-017-11188-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33665
Walker ME, Souza PR, Colas RA, Dalli J(2017). 13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis. FASEB Journal vol. 31, (8) 3636-3648.
10.1096/fj.201700268
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25142
Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J et al.(2017). Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming. Nature Biomedical Engineering vol. 1, (7) 0094-0094.
10.1038/s41551-017-0094
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62241
Hansen TV, Dalli J, Serhan CN(2017). The Novel Lipid Mediator PD1n-3DPA: An Overview of the Structural Elucidation, Synthesis, Biosynthesis and Bioactions. Prostaglandins and Other Lipid Mediators
10.1016/j.prostaglandins.2017.06.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24506
Vik A, Dalli J, Hansen TV(2017). Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid. Bioorg Med Chem Lett vol. 27, (11) 2259-2266.
10.1016/j.bmcl.2017.03.079
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23085
PERRETTI M, Dalli J, Colas R, Federici Canova D, Gobbetti T(2017). Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection. Proceedings of the National Academy of Sciences of the United States of America vol. 114, (15) 3963-3968.
10.1073/pnas.1617290114
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22700
China L, Maini A, Colas R, Ly L, Dalli J, Gilroy D, O'Brien A, Infection ATTIREAP (2017). Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities. JOURNAL OF HEPATOLOGY. Conference: Hepathology vol. 66, S390-S390.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24505
Perretti M, Di Filippo C, D'Amico M, Dalli J(2017). Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide. PLoS One vol. 12, (4) Article 0175786, e0175786-e0175786.
10.1371/journal.pone.0175786
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22626
Norling LV, Ly L, Dalli J(2017). Resolving inflammation by using nutrition therapy: roles for specialized proresolving mediators. Curr Opin Clin Nutr Metab Care vol. 20, (2) 145-152.
10.1097/MCO.0000000000000353
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18759
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. (2017). Sex differences in the inflammatory response and inflammation-induced vascular dysfunction. LANCET. Conference: FASEB vol. 389, 20-20.
10.1016/s0140-6736(17)30416-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22462
Dalli J, Colas RA, Arnardottir H, Serhan CN(2017). Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution. Immunity vol. 46, (1) 92-105.
10.1016/j.immuni.2016.12.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18502
Perretti M, Cooper D, Dalli J, Norling LV(2017). Immune resolution mechanisms in inflammatory arthritis. Nat Rev Rheumatol vol. 13, (2) 87-99.
10.1038/nrrheum.2016.193
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18889
Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR, Serhan CN(2016). Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation. J Immunol vol. 197, (11) 4444-4452.
10.4049/jimmunol.1600837
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18956
AHLUWALIA A(2016). Accelerated resolution underlies sex differences in the inflammatory response in human. Journal of Clinical Investigation vol. 127, (1) 169-182.
10.1172/JCI89429.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18792
Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV, Vik A(2016). Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins. J Nat Prod vol. 79, (10) 2693-2702.
10.1021/acs.jnatprod.6b00634
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18855
DALLI J(2016). Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages. Proceedings of the National Academy of Sciences of USA vol. 113, (43)
10.1073/pnas.1607003113
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16193
DALLI J, Colas RC(2016). Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes. Critical Care Medicine
10.1097/CCM.0000000000002014
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16189
DALLI JP(2016). Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses. Science Translational Medicine vol. 8, (353)
10.1126/scitranslmed.aaf7483
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16182
Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN(2016). Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. Journal of Immunology vol. 197, (6) 2362-2368.
10.4049/jimmunol.1502268
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23490
Norling L, Headland S, Dalli J, Arnardottir H, Jones H, Haworth O, Serhan C, Perretti M (2016). PRO-RESOLVING AND CARTILAGE-PROTECTIVE ACTIONS OF RESOLVIN D1 IN INFLAMMATORY ARTHRITIS. ANNALS OF THE RHEUMATIC DISEASES. Conference: EULAR vol. 75, 673-673.
10.1136/annrheumdis-2016-eular.6116
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24545
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al.(2016). Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis. JCI Insight vol. 1, (5)
10.1172/jci.insight.85922
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12017
Dalli J(2016). LIPID MEDIATORS AND THE RESOLUTION OF CHRONIC INFLAMMATION: IMPLICATIONS FOR ARTHRITIS THERAPY. OSTEOARTHRITIS AND CARTILAGE vol. 24, S2-S2.
10.1016/j.joca.2016.01.021
Hansen TV, Dalli J, Serhan CN(2016). Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double di-oxygenation isomers. RSC Adv vol. 6, (34) 28820-28829.
10.1039/C6RA00414H
Dalli J, Chiang N, Serhan CN(2015). Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections. Nat Med vol. 21, (9) 1071-1075.
10.1038/nm.3911
Chiang N, Dalli J, Colas RA, Serhan CN(2015). Identification of resolvin D2 receptor mediating resolution of infections and organ protection. J Exp Med vol. 212, (8) 1203-1217.
10.1084/jem.20150225
Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Canova DF, Perretti M, Brunelleschi S(2015). Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen. Life Sciences vol. 126, 28-36.
10.1016/j.lfs.2015.01.025
Dalli J, Chiang N, Serhan CN(2014). Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection. Proc Natl Acad Sci U S A vol. 111, (44) E4753-E4761.
10.1073/pnas.1415006111
Mirakaj V, Dalli J, Granja T, Rosenberger P, Serhan CN(2014). Vagus nerve controls resolution and pro-resolving mediators of inflammation. J Exp Med vol. 211, (6) 1037-1048.
10.1084/jem.20132103
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M(2014). 15. Neutrophils in GCA. Rheumatology (Oxford) vol. 53, (suppl 2)
10.1093/rheumatology/keu200
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M (2014). NEUTROPHILS IN GCA. RHEUMATOLOGY. vol. 53, 9-9.
Headland S, Norling L, Patel H, Dalli J, Kelly S, Pitzalis C, Dell'Accio F, Perretti M (2014). A novel mechanism for protecting the arthritic joint: microparticles deliver Annexin A1 into cartilage (146.8). The FASEB Journal. vol. 28,
10.1096/fasebj.28.1_supplement.146.8
Norling L, Headland S, Dalli J, Serhan C, Perretti M (2014). Resolvin D1 protects from neutrophil mediated joint destruction in inflammatory arthritis (146.5). The FASEB Journal. vol. 28,
10.1096/fasebj.28.1_supplement.146.5
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M(2014). Investigational analysis reveals a potential role for neutrophils in giant-cell arteritis disease progression. Circulation Research vol. 114, (2) 242-248.
10.1161/CIRCRESAHA.114.301374
Dalli J, Norling LV, Montero-Melendez T, Canova DF, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al.(2014). Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis. EMBO Molecular Medicine vol. 6, (1) 27-42.
10.1002/emmm.201303503
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10756
Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M(2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Molecular and Cellular Proteomics vol. 12, (8) 2205-2219.
10.1074/mcp.M113.028589
Norling LV, Dalli J(2013). Microparticles are novel effectors of immunity. Curr Opin Pharmacol vol. 13, (4) 570-575.
10.1016/j.coph.2013.05.008
Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M, Wheatley C(2013). Biphasic modulation of nos expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: Downstream regulation of COX-2, IL-1 β, TNF-α, IL-6, and HMGB1 expression. Mediators of Inflammation vol. 2013,
10.1155/2013/741804
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19119
Dalli J, Consalvo AP, Ray V, Filippo CD, D'Amico M, Mehta N, Perretti M(2013). Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A<inf>4</inf> receptor. Journal of Immunology vol. 190, (12) 6478-6487.
10.4049/jimmunol.1203000
Montero-Melendez T, Dalli J, Perretti M(2013). Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors. Cell Death and Differentiation vol. 20, (4) 567-575.
10.1038/cdd.2012.154
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19645
Perretti M, Dalli J, Norling LV, Melendez TM, Hinds C (2013). Neutrophil Microparticles are heterogenous in content and function. The FASEB Journal. vol. 27, 138.5-138.5.
10.1096/fasebj.27.1_supplement.138.5
Dalli J, Montero-Melendez T, McArthur S, Perretti M(2012). Annexin A1 N-terminal derived peptide Ac2-26 exerts chemokinetic effects on human neutrophils. Frontiers in Pharmacology vol. 3 FEB,
10.3389/fphar.2012.00028
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18353
Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G, Lucattelli M(2012). Genetic ablation of the Fpr1 gene confers protection from smoking-induced lung emphysema in mice. American Journal of Respiratory Cell and Molecular Biology vol. 47, (3) 332-339.
10.1165/rcmb.2012-0036OC
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M(2012). Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: Receptor-dependent actions. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 32, (8) 1970-1978.
10.1161/ATVBAHA.112.249508
Norling L, Dalli J, Flower R, Serhan C, Perretti M (2012). RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS. RHEUMATOLOGY. vol. 51, 47-48.
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M (2012). Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions. The FASEB Journal. vol. 26, 835.17-835.17.
10.1096/fasebj.26.1_supplement.835.17
Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M, Rankin SM(2012). Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow. FASEB Journal vol. 26, (1) 387-396.
10.1096/fj.11-182089
Norling LV, Dalli J, Serhan CN, Perretti M (2011). RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS. INFLAMMATION RESEARCH. vol. 60, 60-60.
Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G, Perretti M(2011). Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A<inf>4</inf> receptor and operative in the inflamed microvasculature. Journal of Immunology vol. 186, (8) 4905-4914.
10.4049/jimmunol.1003145
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al.(2011). Anti-inflammatory role of the murine formyl-peptide receptor 2: Ligand-specific effects on leukocyte responses and experimental in-flammation (The Journal of Immunology (2010) 184, (2611-2619)). Journal of Immunology vol. 186, (4) 2684-2685.
10.4049/jimmunol.1090139
Brown SM, Dalli J, Perretti M, Bush A, Davies JC, Lloyd CM(2011). THE INFLAMMATORY RESOLUTION PROTEIN ANNEXIN A1 AND THE PAEDIATRIC CF AIRWAY. PEDIATRIC PULMONOLOGY265-266.
Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F(2010). Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature. Blood vol. 116, (20) 4288-4296.
10.1182/blood-2010-02-270520
Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, Godson C(2010). FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. FASEB J vol. 24, (11) 4240-4249.
10.1096/fj.10-159913
Perretti M, Dalli J, Bolla M, Padron J (2010). 561 THE CINOD NCX 429 INHIBITS MICROVASCULAR INFLAMMATION THROUGH ITS NO-RELEASING PROPERTIES. Osteoarthritis and Cartilage. vol. 18,
10.1016/s1063-4584(10)60588-2
Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M(2010). Downstream gene activation of the receptor ALX by the agonist annexin A1. PLoS One vol. 5, (9)
10.1371/journal.pone.0012771
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10712
Dalli J, Rosignoli G, Hayhoe RPG, Edelman A, Perretti M(2010). CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway. AM J PATHOL vol. 177, (1) 176-186.
10.2353/ajpath.2010.091149
Dalli J, Rosignoli G, Hayhoe RPG, Edelman A, Perretti M(2010). CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway. Am J Pathol vol. 177, (1) 176-186.
10.2353/ajpath.2010.091149
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M(2010). Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions. FASEB JOURNAL vol. 24,
Pederzoli-Ribeil M, Maione F, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F (2010). "Super" Annexin-A1: a novel tool to regulate neutrophil-driven inflammation?. EUR J CLIN INVEST. vol. 40, 47-47.
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al.(2010). Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation. J Immunol vol. 184, (5) 2611-2619.
10.4049/jimmunol.0903526
Brancaleone V, Dalli J, Perretti M (2010). Mobilization of Annexin A1 in human polymorphonuclear leukocytes (PMN). EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. vol. 40, 36-37.
Perretti M, Dalli J(2009). Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics. Br J Pharmacol vol. 158, (4) 936-946.
10.1111/j.1476-5381.2009.00483.x
Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M, Oliani SM(2009). Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation. AM J PATHOL vol. 174, (1) 177-183.
10.2353/ajpath.2009.080342
Dalli J, Norling LV, Renshaw D, Cooper D, Leung K-Y, Perretti M(2008). Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles. Blood vol. 112, (6) 2512-2519.
10.1182/blood-2008-02-140533
Gavins FNE, Dalli J, Flower RJ, Granger DN, Perretti M(2007). Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation. FASEB J vol. 21, (8) 1751-1758.
10.1096/fj.06-7842com
Renshaw D, Dalli J, Kamal A, Perretti M (2006). Disinct patterns of gene expression induced by annexin 1 activation of the ALXR receptor in HEK293 cells. FASEB JOURNAL. vol. 20, A646-A646.
10.1096/fasebj.20.4.a646-a
Renshaw D, Sawmynadan P, Dalli J, Perretti M (2006). Glueocorticoid regulated expression of the anti-inflammatory receptor ALXR. FASEB JOURNAL. vol. 20, A645-A645.
10.1096/fasebj.20.4.a645-c
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