Publications: Prof Jude Fitzgibbon
Rio-Machin A, Vulliamy T, Hug N, Walne A, Tawana K, Cardoso S, Ellison A, Pontikos N et al.(2020).
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants. Nature Communications
vol. 11,
(1)
Kumar EA, Okosun J, Fitzgibbon J(2020).
The Biological Basis of Histologic Transformation. Hematology/Oncology Clinics of North America
vol. 34,
(4)
771-784.
Dokal I, Tummala H, Vulliamy T, Walne A(2020).
A frameshift variant in the specificity protein 1 triggers superactivation of SP1-mediated transcription in familial bone marrow failure. Proceedings of the National Academy of Sciences of USA
Article 32636268,
Fitzgibbon J, Park S, Cook G, Paiva B, Gloghini A, Van Breda E, Busti F, Garderet L et al.(2020).
Recent Advancements in Hematology: Knowledge, Methods and Dissemination, Part 1. Bloods—International Open Access Journal of Hematology
vol. 1,
(1)
Araf S, Korfi K, Bewicke-Copley F, Wang J, Cogliatti S, Kumar E, Forrer F, Barrington SF et al.(2020).
Genetic heterogeneity highlighted by differential FDG-PET response in diffuse large B-cell lymphoma. Haematologica
vol. 105,
(6)
E318-E321.
Waclawiczek A, Hamilton A, Rouault-Pierre K, Abarrategi A, Albornoz MG, Miraki-Moud F, Bah N, Gribben J et al.(2020).
Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia. Journal of Clinical Investigation
vol. 130,
(6)
3038-3050.
Cucco F, Barrans S, Sha C, Clipson A, Crouch S, Dobson R, Chen Z, Thompson JS et al.(2020).
Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit. Leukemia
vol. 34,
(5)
1329-1341.
Maybury B, Fitzgibbon J, Calado D (2020).
An immunocompetent, spontaneous mouse model of DLBCL for studying the response to R-CHOP and identifying new treatment targets. BRITISH JOURNAL OF HAEMATOLOGY.
vol. 189,
110-111.
Fitzgibbon J, Busca A, Gloghini A, López-Guillermo A, Orazi A, Carlo-Stella C, Andrès E, Van Breda E et al.(2020).
Recent Advancements in Hematology: Knowledge, Methods and Dissemination. Hemato
vol. 1,
(1)
5-6.
Charrot S, Armes H, Rio-Machin A, Fitzgibbon J(2020).
AML through the prism of molecular genetics. British Journal of Haematology
vol. 188,
(1)
49-62.
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J(2019).
Follicular lymphoma. Nature Reviews Disease Primers
vol. 5,
(1)
Jurinovic V, Passerini V, Oestergaard MZ, Knapp A, Mundt K, Araf S, Richter J, Fitzgibbon J et al. (2019).
Evaluation of the m7-FLIPI in Patients with Follicular Lymphoma Treated within the Gallium Trial: EZH2 mutation Status May be a Predictive Marker for Differential Efficacy of Chemotherapy. Blood.
vol. 134,
122-122.
Bewicke-Copley F, Korfi K, Araf S, Kumar EA, Cummin TEC, Ashton-Key M, Barrans S, Van Hoppe S et al.(2019).
Longitudinal Analyses of Diagnostic-Relapse Biopsies of Diffuse Large B Cell Lymphoma Reveal a Poor Risk Subset of ABC Patients Based on the Expression of a 30 Gene Panel. Blood
vol. 134,
(Supplement_1)
2769-2769.
Ortega-Molina A, Deleyto-Seldas N, Carreras J, Sanz A, Lebrero-Fernández C, Menéndez C, Vandenberg A, Fernández-Ruiz B et al.(2019).
Oncogenic Rag GTPase signalling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR. Nature Metabolism
vol. 1,
(8)
775-789.
Okosun J, Bödör C, Batlevi C, Nagy N, Michot J, Schneider T, Alizadeh H, Simon Z et al.(2019).
EZH2 GAIN‐OF‐FUNCTION MUTATIONS ARE NOT ASSOCIATED WITH MORE FAVORABLE PROGNOSIS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA (FL): A PRELIMINARY ANALYSIS ON 590 PATIENTS. Hematological Oncology
vol. 37,
192-193.
Korfi K, Araf S, Bewicke¿Copley F, Kumar E, Cummin T, Ashton¿Key M, Barrans S, Van Hoppe S et al.(2019).
LONGITUDINAL ANALYSES OF DIAGNOSTIC‐RELAPSE BIOPSIES OF DIFFUSE LARGE B CELL LYMPHOMA SUGGEST THAT RELAPSE IS MEDIATED BY DISTINCT MECHANISMS IN ABC AND GCB LYMPHOMA. Hematological Oncology
vol. 37,
142-143.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.(2019).
Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma (Leukemia, (2018), 32, 5, (1261-1265), 10.1038/s41375-018-0043-y). Leukemia
vol. 33,
(6)
Kumar E, Korfi K, Bewicke-Copley F, Witzig T, Leukam M, Ansell S, Scott J, Rallis K et al.(2019).
MUTATIONS AFFECTING THE CREBBP HAT DOMAIN PREDICT RESPONSE TO MTOR INHIBITORS EVEROLIMUS AND TEMSIROLIMUS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA. HemaSphere
vol. 3,
Rio-Machin A, Vulliamy T, Hug N, Caceres JF, Fitzgibbon J, Dokal I(2019).
PF213 THE GENETIC LANDSCAPE OF FAMILIAL MDS/AML; RECURRING MUTATIONS IN THE RNA HELICASE DHX34 LEADING TO DEFECTS IN NONSENSE-MEDIATED RNA DECAY. HemaSphere
vol. 3,
(S1)
Kumar E, Korfi K, Bewicke-Copley F, Witzig T, Leukam M, Ansell S, Scott J, Rallis K et al.(2019).
PF513 MUTATIONS AFFECTING THE CREBBP HAT DOMAIN PREDICT RESPONSE TO MTOR INHIBITORS EVEROLIMUS AND TEMSIROLIMUS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA. HemaSphere
vol. 3,
(S1)
Bödör C, Batlevi C, Nagy N, Michot J-M, Schneider T, Alizadeh H, Simon Z, Vose J et al.(2019).
PS1247 EZH2 GAIN-OF-FUNCTION MUTATIONS ARE NOT ASSOCIATED WITH MORE FAVORABLE PROGNOSIS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: A PRELIMINARY ANALYSIS ON 590 PATIENTS. HemaSphere
vol. 3,
(S1)
568-569.
Heward J, Koniali L, D¿Avola A, Close K, Yeomans A, Johnson P, Okosun J, Neve R et al.(2019).
S844 KDM5 INHIBITION OFFERS A NOVEL THERAPEUTIC STRATEGY FOR THE TREATMENT OF KMT2D MUTANT LYMPHOMAS. HemaSphere
vol. 3,
(S1)
376-377.
Araf S, Wang J, Ashton-Key M, Korfi K, Di Bella D, Rio-Machin A, Odabashian M, Foria V et al.(2019).
Transmission of diffuse large B-cell lymphoma by an allogeneic stem-cell transplant. Haematologica
vol. 104,
(4)
e174-e177.
Merron B, Kazmi-Stokes S, Cummin T, Barrans S, Araf S, Korfi K, Pascua LDL, Caddy J et al.(2019).
Precision medicine for patients with lymphoma; the Bloodwise Precision Medicine for Aggressive Lymphomas (PMAL) consortium. Clinical Medicine
vol. 19,
(Suppl 2)
100-101.
Jakobsen JS, Laursen LG, Schuster MB, Pundhir S, Schoof E, Ge Y, D'Altri T, Vitting-Seerup K et al.(2019).
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML. Science Advances
vol. 5,
(7)
Brown AL, Armstrong M, Lawrence D, Wang P, Arts P, Duployez N, Churpek J, Tawana K et al.(2018).
Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB. Blood
vol. 132,
(Supplement 1)
5241-5241.
DOKAL I, TUMMALA H, VULLIAMY T(2018).
homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita-like phenotypes. Blood
vol. 132,
1349-1353.
Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S et al.(2018).
Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells. Leukemia
vol. 32,
(8)
1818-1822.
Okosun J, Kridel R, Fitzgibbon J(2018).
Rituximab as a first step in tackling transformation. The Lancet Haematology
vol. 5,
(8)
e326-e327.
Heward JA, Kumar EA, Korfi K, Okosun J, Fitzgibbon J(2018).
Precision medicine and lymphoma. Curr Opin Hematol
vol. 25,
(4)
329-334.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.(2018).
Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma. Leukemia
vol. 32,
(5)
1258-1263.
Al Seraihi AF, Rio-Machin A, Tawana K, Bödör C, Wang J, Nagano A, Heward JA, Iqbal S et al.(2018).
GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML. Leukemia
vol. 32,
(11)
2502-2507.
Araf S, Okosun J, Fitzgibbon J(2018).
Predicting early relapse in follicular lymphoma: have we turned a corner?. The Lancet Oncology
vol. 19,
(4)
441-442.
Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S et al.(2017).
Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells. Leukemia
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward JA et al. (2017).
Genomic Profiling Reveals Spatial Intra-Tumor Heterogeneity in Follicular Lymphoma. BLOOD.
vol. 130,
Araf S, Korfi K, Nagano A, Cummin TEC, Bentley M, Thorner AR, Ashton-Key M, Calaminici M et al. (2017).
Longitudinal Analyses of the Genomic, Transcriptomic, and T Cell Repertoire in Diffuse Large B Cell Lymphoma Demonstrates Changes in Signaling and Immune Recognition at Relapse. BLOOD.
vol. 130,
Gascoyne RD, Nadel B, Pasqualucci L, Fitzgibbon J, Payton JE, Melnick A, Weigert O, Tarte K et al.(2017).
Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015. Hematological Oncology
vol. 35,
(4)
397-407.
Horton SJ, Giotopoulos G, Yun H, Vohra S, Sheppard O, Bashford-Rogers R, Rashid M, Clipson A et al. (2017).
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors. Nature Cell Biology.
vol. 19,
1093-1104.
Rio-Machin A, Gómez-López G, Muñoz J, Garcia-Martinez F, Maiques-Diaz A, Alvarez S, Salgado RN, Shrestha M et al.(2017).
The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia. Leukemia
vol. 31,
(9)
2000-2005.
Tawana K, Wang J, Király PA, Kállay K, Benyó G, Zombori M, Csomor J, Al Seraihi A et al.(2017).
Recurrent somatic JAK-STAT pathway variants within a RUNX1-mutated pedigree. European Journal of Human Genetics
vol. 25,
(8)
1020-1024.
Cummin TE, Araf S, Du M, Barrans S, Bentley MA, Clipson A, Wang M, Ahmed S et al.(2017).
PROGNOSTIC SIGNIFICANCE AND CORRELATION TO GENE EXPRESSION PROFILE OF EZH2 MUTATIONS IN DIFFUSE LARGE B‐CELL LYMPHOMA (DLBL) IN 2 LARGE PROSPECTIVE STUDIES. Hematological Oncology
vol. 35,
(S2)
158-159.
Tawana K, Rio-Machin A, Preudhomme C, Fitzgibbon J(2017).
Familial CEBPA-mutated acute myeloid leukemia. Seminars in Hematology
vol. 54,
(2)
87-93.
Korfi K, Ali S, Heward JA, Fitzgibbon J(2017).
Follicular lymphoma, a B cell malignancy addicted to epigenetic mutations. Epigenetics
vol. 12,
(5)
370-377.
Casado P, Wilkes E, Hadi MM, Rajeeve V, Miraki-Moud F, Pike R, Del Rio-Machin A, Iqbal S et al. (2016).
Differentiation Status Revealed By Shotgun Phosphoproteomics Determines Sensitivity of Primary AML Cells to Kinase Inhibitors. Blood.
vol. 128,
840-840.
Fitzgibbon J(2016).
Genomic Discovery, Prognosis, and Target Therapy Development. Blood
vol. 128,
(22)
Rio-Machin A, Gomez-Lopez G, Maiques-Diaz A, Alvarez S, Calasanz MJ, Fitzgibbon J, Cigudosa JC (2016).
HDAC Inhibitors As Novel Targeted Therapies for NUP98-HOXA9 AML Patients. Blood.
vol. 128,
2685-2685.
Noerenberg D, Mansouri L, Young E, Mareike F, Abdulla M, Asmar F, Gonzalez-Farre B, Anna T et al. (2016).
NFKBIE Deletions: A Novel Marker of Clinical Aggressiveness in Primary Mediastinal B-Cell Lymphoma. BLOOD.
vol. 128,
Britton DJ, Wilkes E, Casado P, Rajeeve V, Fitzgibbon J, Gribben J, Cutillas PR (2016).
Proteomic Analysis Directs Effective Drug Selection in Relapsed AML By Quantifying Drug Targets. Blood.
vol. 128,
5265-5265.
Al Seraihi A, Rio-Machin A, Tawana K, Bödör C, Araf S, Heward JA, Smith M, Iqbal S et al. (2016).
Variable Penetrance Is Linked with Monoallelic Gene Expression in Inherited GATA2-Mutated MDS/AML. Blood.
vol. 128,
3916-3916.
Noerenberg* D, Mansouri* L, Young E, Mareike F, Abdulla M, Asmar F, Gonzalez-Farre B, Anna T et al.(2016).
ΝFΚΒΙΕ Deletions: A Novel Marker of Clinical Aggressiveness in Primary Mediastinal B-Cell Lymphoma. Blood
vol. 128,
(22)
609-609.
Stunnenberg HG, Abrignani S, Adams D, de Almeida M, Altucci L, Amin V, Amit I, Antonarakis SE et al.(2016).
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell
vol. 167,
(5)
1145-1149.
Mansouri L, Noerenberg D, Young E, Mylonas E, Abdulla M, Frick M, Asmar F, Ljungström V et al.(2016).
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma. Blood
vol. 128,
(23)
2666-2670.
Araf S, Korfi K, Rahim T, Davies A, Fitzgibbon J(2016).
Advances in the molecular diagnosis of diffuse large B-cell lymphoma in the era of precision medicine. Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare
vol. 16,
(10)
1093-1102.
Araf S, Fitzgibbon J(2016).
Pediatric-type FL: Simply different. Blood
vol. 128,
(8)
1030-1031.
Ripperger T, Tawana K, Kratz C, Schlegelberger B, Fitzgibbon J, Steinemann D(2016).
Clinical utility gene card for: Familial platelet disorder with associated myeloid malignancies. European Journal of Human Genetics
vol. 24,
(8)
e1-e4.
Tummala H, Walne AJ, Williams M, Bockett N, Collopy L, Cardoso S, Ellison A, Wynn R et al.(2016).
DNAJC21 Mutations Link a Cancer-Prone Bone Marrow Failure Syndrome to Corruption in 60S Ribosome Subunit Maturation. American Journal of Human Genetics
vol. 99,
(1)
115-124.
Larrea E, Fernandez-Mercado M, Ceberio I, Guerra-Assunção JA, Okosun J, Fitzgibbon J, Lawrie C(2016).
110 Follicular lymphoma cases harbour recurrent mutations in micro-RNA binding sites of genes associated with lymphomagenesis. European Journal of Cancer
vol. 61,
s11-s12.
Larrea E, Fernandez-Mercado M, Ceberio I, Guerra-Assuncao JA, Okosun J, Fitzgibbon J, Lawrie C (2016).
Follicular lymphoma cases harbour recurrent mutations in microRNA binding sites of genes associated with lymphomagenesis. EUROPEAN JOURNAL OF CANCER.
vol. 61,
S11-S12.
GROSE RP, Dawkins JBN, Wang J, maniati, heward, koniali, kocher, martin et al.(2016).
Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma. Cancer Research
Araf S, Wang J, Pangault C, Kotsiou E, Hoxha E, Iqbal S, Davies J, Johnson P et al. (2016).
GENOMIC PROFILING REVEALS SPATIAL HETEROGENEITY IN FOLLICULAR LYMPHOMA: IMPLICATIONS FOR PRECISION MEDICINE. HAEMATOLOGICA.
vol. 101,
270-270.
Britton D, Casado P, Rajeeve V, Wilkes E, Smith R, Fitzgibbon J, Gribben J, Cutillas P (2016).
PROTEOMIC ANALYSIS OF RELAPSE AML IDENTIFIES OPPORTUNITIES FOR THERAPEUTIC INTERVENTION IN INDIVIDUAL PATIENTS. HAEMATOLOGICA.
vol. 101,
373-373.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al.(2016).
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma (vol 48, pg 183, 2016). NATURE GENETICS
vol. 48,
(6)
700-700.
Rio-Machin A, Cardoso S, Tawana K, Wang J, Chelala C, Plagnol V, Wallis Y, Ryan G et al. (2016).
WHOLE EXOME SEQUENCING REVEALS NOVEL CANDIDATE GENES IN FAMILIAL MDS/AML. HAEMATOLOGICA.
vol. 101,
205-206.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Seraihi AFA et al.(2016).
Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet
vol. 48,
(6)
700-700.
DOKAL I(2016).
Germline heterozygous DDX41 vriants in a subset of familial myelodysplasia and acute myeloid leukaemia. Leukemia
Okosun J, Montoto S, Fitzgibbon J(2016).
The routes for transformation of follicular lymphoma. Current Opinion in Hematology
vol. 23,
(4)
1-1.
Kotsiou E, Okosun J, Besley C, Iqbal S, Matthews J, Fitzgibbon J, Gribben J, DAVIES JK(2016).
TNFRSF14 aberrations in follicular lymphoma increase clinically significant allogeneic T-cell responses. Blood
vol. 128,
(1)
72-81.
Strefford JC, Fitzgibbon J, Rose-Zerilli MJJ, Bödör C(2016).
The genetics of mature B-cell malignancies. The Genetic Basis of Haematological Cancers,
Tawana K, Fitzgibbon J(2016).
Inherited DDX41 mutations: 11 genes and counting. Blood
vol. 127,
(8)
960-961.
Klapper W, Klein U, De Silva NS, Zha S, Crowe JL, Dai B, Weilemann A, Okosun J et al.(2016).
5. Follicular lymphoma. Malignant Lymphomas,
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al.(2016).
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nature Genetics
vol. 48,
(2)
183-188.
Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, De Wit TD, Eichinger S et al.(2016).
The european hematology association roadmap for european hematology research: A consensus document. Haematologica
vol. 101,
(2)
115-208.
Araf S, Okosun J, Koniali L, Fitzgibbon J, Heward J(2016).
Epigenetic dysregulation in follicular lymphoma. Epigenomics
vol. 8,
(1)
77-84.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al. (2015).
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nature Genetics.
Tawana K, Wang J, Renneville A, Bödör C, Hills R, Loveday C, Savic A, Van Delft FW et al.(2015).
Disease evolution and outcomes in familial AML with germline CEBPA mutations. Blood
vol. 126,
(10)
1214-1223.
Carlotti E, Wrench D, Rosignoli G, Marzec J, Sangaralingam A, Hazanov L, Michaeli M, Hallam S et al.(2015).
High throughput sequencing analysis of the immunoglobulin heavy chain gene from flow-sorted B cell sub-populations define the dynamics of follicular lymphoma clonal evolution. PLoS ONE
vol. 10,
(9)
Tawana K, Wang J, Kiraly PA, Kallay K, Benyo G, Krivan G, Csomor J, Fitzgibbon J et al. (2015).
CONVERGENCE OF SOMATIC MUTATIONS WITHIN THE JAK-STAT SIGNALLING PATHWAY IN A NOVEL RUNX1-MUTATED PEDIGREE. HAEMATOLOGICA.
vol. 100,
9-10.
Koniali L, Heward J, Loveday C, Wilkins L, Ishfaq M, Wang J, Okosun J, Packham G et al. (2015).
KDM5 INHIBITION LEADS TO INCREASED H3K4ME3 LEVELS AND CELL DEATH IN GERMINAL CENTRE LYMPHOMA CELL LINES INDEPENDENT OF MLL2 MUTATION STATUS. HAEMATOLOGICA.
vol. 100,
104-104.
Noerenberg D, Frick M, Couronne L, Lenze D, Baldus CD, Bastard C, Okosun J, Fitzgibbon J et al. (2015).
NFKBIE MUTATIONS OCCUR IN 15% OF GCB DLBCL AND IN VARIOUS OTHER LYMPHOID MALIGNANCIES. HAEMATOLOGICA.
vol. 100,
549-549.
Kotsiou E, Okosun J, Clear AJ, Iqbal S, Fitzgibbon J, Gribben JG, Davies JK (2014).
TNFRSF14 aberrations in Follicular Lymphoma B Cells Result in Increased Alloresponses in Vitro and in Vivo. Blood.
vol. 124,
2426-2426.
Haider S, Wang J, Nagano A, Desai A, Arumugam P, Dumartin L, Fitzgibbon J, Hagemann T et al.(2014).
A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma. Genome Medicine
vol. 6,
(12)
Rohatiner AZS, Smith ML, Spinelli O, Rambaldi A, Bassan R, di Bona E, Rodeghiero F, Raimondi R et al.(2014).
Myeloblative therapy with autologous haematopoietic stem cell support as consolidation of first remission in acute myeloid leukaemia - very long follow-up. Br J Haematol
vol. 167,
(5)
724-726.
Okosun J, Packham G, Fitzgibbon J(2014).
Investigational epigenetically targeted drugs in early phase trials for the treatment of haematological malignancies. Expert Opin Investig Drugs
vol. 23,
(10)
1321-1332.
Bouska A, McKeithan TW, Deffenbacher KE, Lachel C, Wright GW, Iqbal J, Smith LM, Zhang W et al.(2014).
Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma. BLOOD
vol. 123,
(11)
1681-1690.
Okosun J, Bödör C, Wang J, Araf S, Yang CY, Pan C, Boller S, Cittaro D et al.(2014).
Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics
vol. 46,
(2)
176-181.
Okosun J, Bödör C, Wang J, Araf S, Yang C-Y, Pan C, Boller S, Cittaro D et al.(2014).
Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nat Genet
vol. 46,
(2)
176-181.
Tawana K, Renneville A, Wang J, Georgiades P, Thomas X, Mialou V, Savic A, Van Delft FW et al. (2013).
Familial AML With Germline CEBPA Mutations: Extended Clinical Outcomes and Analysis Of Secondary Mutations Using Whole Exome Sequencing. Blood.
vol. 122,
740-740.
Popov N, Maniati E, Marzec J, Okosun J, Scott R, Kranz A, Stewart F, Chelala C et al. (2013).
Investigating The Role Of MLL2 (Mll4) In B Cell Development. Blood.
vol. 122,
343-343.
Mutsaers PGNJ, van de Loosdrecht AA, Tawana K, Bödör C, Fitzgibbon J, Menko FH(2013).
Highly variable clinical manifestations in a large family with a novel GATA2 mutation. Leukemia
vol. 27,
(11)
2247-2248.
Bödör C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S et al.(2013).
EZH2 mutations are frequent and represent an early event in follicular lymphoma. Blood
vol. 122,
(18)
3165-3168.
Okosun J, Bödör C, Wang J, Araf S, Chelala C, Fitzgibbon J(2013).
Genomic analysis reveals epigenetic ‘addiction’ underpinning follicular lymphoma and its transformation – a rationale for targeted epigenetic therapies. Clinical Epigenetics
vol. 5,
(Suppl 1)
Gertner-Dardenne J, Fauriat C, Orlanducci F, Thibult M-L, Pastor S, Fitzgibbon J, Bouabdallah R, Xerri L et al.(2013).
The co-receptor BTLA negatively regulates human V gamma 9V delta 2 T-cell proliferation: a potential way of immune escape for lymphoma cells. BLOOD
vol. 122,
(6)
922-931.
Green CL, Tawana K, Hills RK, Bödör C, Fitzgibbon J, Inglott S, Ancliff P, Burnett AK et al.(2013).
GATA2 mutations in sporadic and familial acute myeloid leukaemia patients with CEBPA mutations. Br J Haematol
vol. 161,
(5)
701-705.
Okosun J, Clear A, Iqbal S, Matthews J, Gribben J, Fitzgibbon J, Davies J (2013).
TNFRSF14 aberrations are associated with death from acute GvHD after reduced-intensity conditioned allogeneic haematopoietic stem cell transplantation for follicular lymphoma. BONE MARROW TRANSPLANTATION.
vol. 48,
S169-S169.
Robbez-Masson LJ, Bödör C, Jones JL, Hurst HC, Fitzgibbon J, Hart IR, Grose RP(2013).
Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing. PLoS One
vol. 8,
(11)
Bouska A, McKeithan T, Deffenbacher KE, Lachel C, Wright GW, Iqbal J, Smith LM, Liu Z et al. (2012).
Genetic Abnormalities in Follicular Lymphoma and Transformed Follicular Lymphoma. BLOOD.
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