Publications: Dr Andrew Stagg
Rodger B, Stagg AJ, Lindsay JO
(
2024
)
.
The role of circulating T cells with a tissue resident phenotype (ex-TRM) in health and disease
.
Frontiers in Immunology
vol.
15
,
Tyler CJ, Hoti I, Griffiths DD, Cuff SM, Andrews R, Keisker M, Ahmed R, Hansen HP et al.
(
2024
)
.
IL-21 conditions antigen-presenting human γδ T-cells to promote IL-10 expression in naïve and memory CD4+ T-cells
.
Discovery Immunology
vol.
3
,
(
1
)
Humphreys DT, Lewis A, Pan‐Castillo B, Berti G, Mein C, Wozniak E, Gordon H, Gadhok R et al.
(
2024
)
.
Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease
.
Journal of Cellular and Molecular Medicine
vol.
28
,
(
9
)
Gordon H, Wichmann K, Lewis A, Sanders T, Wildemann M, Hoti I, Hornsby E, Kok KB et al.
(
2023
)
.
Human Intestinal Dendritic Cells Can Overcome Retinoic Acid Signaling to Generate Proinflammatory CD4 T Cells with Both Gut and Skin Homing Properties
.
The Journal of Immunology
vol.
212
,
(
1
)
96
-
106
.
Gordon H, Rodger B, Lindsay JO, Stagg AJ
(
2023
)
.
Recruitment and Residence of Intestinal T Cells – Lessons for Therapy in Inflammatory Bowel Disease
.
Journal of Crohn's and Colitis
vol.
17
,
(
8
)
1326
-
1341
.
Hornsby E, Gadhok R, Yadon AN, Lindsay JO, Stagg AJ
(
2023
)
.
DOP04 Single cell RNA sequencing reveals a potential role for IFNγ in priming circulating monocytes for intestinal inflammatory function in Crohn’s Disease
.
Journal of Crohn's and Colitis
vol.
17
,
(
Supplement_1
)
i61
-
i62
.
Hornsby E, Gadhok R, Yadon AN, Lindsay JO, Stagg AJ
(
2023
)
.
Single cell RNA sequencing reveals a potential role for IFNγ in priming circulating monocytes for intestinal inflammatory function in Crohn's Disease
.
JOURNAL OF CROHNS & COLITIS
.
vol.
17
,
I61
-
I62
.
Hornsby E, King HW, Peiris M, Buccafusca R, Lee W-YJ, Wing ES, Blackshaw LA, Lindsay JO et al.
(
2022
)
.
The cation channel TRPM8 influences the differentiation and function of human monocytes
.
Journal of Leukocyte Biology
vol.
112
,
(
3
)
365
-
381
.
Mathew L, Savage M, Pardieu C, O’Brien M, Sze SK, Eberl M, Stagg A, Gasparetto M et al.
(
2022
)
.
OP37 Bacterial suppression of intestinal fungi via activation of human gut Vδ2+ T-cells
.
Journal of Crohn's and Colitis
vol.
16
,
(
Supplement_1
)
i043
-
i044
.
Rodger B, Gordon H, Hoti I, Stagg A, Lindsay J
(
2022
)
.
P003 Identification of an intestine-derived ex-Trm population in the blood of healthy individuals and patients with Inflammatory Bowel Disease
.
Journal of Crohn's and Colitis
vol.
16
,
(
Supplement_1
)
i136
-
i136
.
Gordon H, Rodger B, Hornsby E, McGuire J, Kok KB, Lindsay JO, Stagg AJ
(
2022
)
.
P039 The role of α4β7+CLA+ ‘dual tropic’ T cells in inflammatory bowel disease
.
Journal of Crohn's and Colitis
vol.
16
,
(
Supplement_1
)
i156
-
i156
.
Stagg AJ, Stackpoole A, Elsley WJ, Knight SC
(
1993
)
.
Acquisition of Chlamydial Antigen by Dendritic Cells and Monocytes
.
Advances in Experimental Medicine and Biology
.
vol.
329
,
581
-
586
.
Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Stagg AJ, Lindsay JO, Whelan K
(
2021
)
.
Prebiotic fructans have greater impact on luminal microbiology and CD3+ T cells in healthy siblings than patients with Crohn's disease: A pilot study investigating the potential for primary prevention of inflammatory bowel disease
.
Clinical Nutrition
vol.
40
,
(
8
)
5009
-
5019
.
Rodger B, Hoti I, Gordon H, Lindsay J, Stagg A
(
2021
)
.
P007 Identification and characterisation of intestine-derived circulating resident memory T cells (ex-Trm) in health and Inflammatory Bowel Disease
.
Journal of Crohn's and Colitis
vol.
15
,
(
Supplement_1
)
s128
-
s128
.
Gordon H, Rodger B, Hoti I, Lindsay JO, Stagg A
(
2021
)
.
P033 Dendritic cells from patients with active IBD imprint pro-inflammatory α4β7+CLA+ T cells with potential for gut and skin homing
.
Journal of Crohn's and Colitis
vol.
15
,
(
Supplement_1
)
s147
-
s147
.
Hornsby E, Yadon AN, Clarke A, Grant E, Lindsay JO, Stagg AJ
(
2021
)
.
P068 The combination of JAK1 and TPL2 or IRAK4 inhibitors is more effective than single agents in reducing TLR-mediated cytokine responses in human monocyte populations
.
Journal of Crohn's and Colitis
vol.
15
,
(
Supplement_1
)
s173
-
s173
.
Gordon H, Hoti I, Wichmann K, Saunders T, Wildemann M, Hornsby E, McCarthy NE, Lindsay JO et al.
(
2021
)
.
P105 Dendritic cells imprint pro-inflammatory α4β7+CLA+ T cells with potential for gut and skin homing
.
Gut
.
Conference:
Posters
vol.
70
,
a95
-
a96
.
McCarthy NE, Stagg AJ, Price CL, Mann ER, Gellatly NL, Al-Hassi HO, Knight SC, Panoskaltsis N
(
2020
)
.
Patients with gastrointestinal irritability after TGN1412-induced cytokine storm displayed selective expansion of gut-homing αβ and γδT cells
.
Cancer Immunology Immunotherapy
Panoskaltsis N, McCarthy NE, Stagg AJ, Mummery CJ, Husni M, Arebi N, Greenstein D, Price CL et al.
(
2020
)
.
Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm
.
Cancer Immunology, Immunotherapy
vol.
70
,
(
4
)
1127
-
1142
.
Ball J, Clear A, Aries J, Charrot S, Besley C, Mee M, Stagg A, Lindsay J et al.
(
2020
)
.
Retinoic acid-responsive CD8 effector T-cells are selectively increased in IL-23-rich tissue in gastrointestinal GvHD
.
Blood
Stagg AJ, Hornsby E, Knight SC
(
2020
)
.
Antigen‐Presenting Cells
.
Encyclopedia of Life Sciences
,
vol.
1
,
Wiley
Whitehouse AL, Mushtaq N, Miyashita L, Barratt B, Khan A, Kalsi H, Koh L, Padovan MG et al.
(
2020
)
.
Airway dendritic cell maturation in children exposed to air pollution
.
PLoS One
vol.
15
,
(
5
)
e0232040
-
e0232040
.
Robledo Retana T, Bradley-Clarke J, Croll T, Rose R, Stagg AJ, Villalba M, Honti I, Pickersgill RW
(
2020
)
.
Lig v 1 structure and the inflammatory response to the Ole e 1 protein family
.
Allergy
Cox SR, Lindsay JO, Fromentin S, Stagg AJ, McCarthy NE, Galleron N, Ibraim SB, Roume H et al.
(
2019
)
.
Effects of Low-FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial
.
Gastroenterology
Waller K, James C, de Jong A, Blackmore L, Ma Y, Stagg A, Kelsell D, O'Dwyer M et al.
(
2019
)
.
ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis
.
Frontiers in Immunology
vol.
10
,
Harrow P, Datta R, Stagg A, Lindsay JO
(
2019
)
.
P012 IL22 expression in intestinal immune cells is not augmented by AHR activation in health or Crohn’s disease
.
Journal of Crohn's and Colitis
.
vol.
13
,
s092
-
s092
.
Hornsby E, Peiris M, Peiris M, King HW, Wing ES, Lindsay JO, Blackshaw LA, Stagg AJ
(
2019
)
.
P016 Constitutive activity of the cation channel TRPM8 regulates monocyte to macrophage transition in humans to control intestinal inflammation
.
Journal of Crohn's and Colitis
.
vol.
13
,
s094
-
s094
.
Hoti I, McCarthy N, Giles E, Ayada I, Harrow P, Gordon H, Stagg A, Lindsay J
(
2019
)
.
P092 Circulating classical monocytes and intestinal macrophages exhibit reduced response to IL-10 in IBD
.
Journal of Crohn's and Colitis
.
vol.
13
,
s131
-
s132
.
Stagg AJ
(
2018
)
.
Intestinal Dendritic Cells in Health and Gut Inflammation
.
Frontiers in Immunology
vol.
9
,
Hedin CRH, Vavricka SR, Stagg AJ, Schoepfer A, Raine T, Puig L, Pleyer U, Navarini A et al.
(
2018
)
.
The Pathogenesis of Extraintestinal Manifestations: Implications for IBD Research, Diagnosis, and Therapy
.
Journal of Crohn's and Colitis
vol.
13
,
(
5
)
541
-
554
.
Cox S, Stagg A, Fromentin S, Ehrlich D, McCarthy N, Galleron N, Levenez F, Lomer M et al.
(
2018
)
.
ADWE-09 Low fodmap diet improves functional-like gastrointestinal symptoms but reduces bifidobacteria in quiescent inflammatory bowel disease
.
Gut
.
Conference:
Small Bowel & Nutrition
vol.
67
,
Dogra H, Peiris M, Stagg A, Blackshaw A, Sanderson IR
(
2018
)
.
OTH-002 Nutrients modulate cytokine release from ex-vivo intestinal mucosa via distinct sensing pathways
.
Conference:
British Society of Gastroenterologya163.2
-
a1a164
.
Mwanza-Lisulo M, Chomba MS, Chama M, Besa EC, Funjika E, Zyambo K, Banda R, Imikendu M et al.
(
2018
)
.
Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines
.
Vaccine
vol.
36
,
(
28
)
4134
-
4141
.
Hedin CRH, Vavricka SR, Stagg AJ, Schoepfer A, Raine T, Puig L, Pleyer U, Navarini A et al.
(
2018
)
.
DOP073 Results of the sixth ECCO Scientific Workshop: The pathogenesis of inflammatory extraintestinal manifestations of inflammatory bowel disease: implications for research, diagnosis, and therapy
.
Journal of Crohn's and Colitis
vol.
12
,
(
supplement_1
)
s80
-
s80
.
Cox S, Stagg A, Fromentin S, Ehrlich D, McCarthy N, Galleron N, Levenez F, Lomer M et al.
(
2018
)
.
Low FODMAP diet improves functional-like gastrointestinal symptoms but reduces bifidobacteria and faecalibacterium prausnitzii in Quiescent inflammatory bowel disease: a randomised controlled trial and metagenomic analysis
.
JOURNAL OF CROHNS & COLITIS
.
vol.
12
,
S87
-
S87
.
Hedin CRH, Vavricka SR, Stagg AJ, Schoepfer A, Raine T, Puig L, Pleyer U, Navarini A et al.
(
2018
)
.
Results of the sixth ECCO Scientific Workshop: The pathogenesis of inflammatory extraintestinal manifestations of inflammatory bowel disease: implications for research, diagnosis, and therapy
.
JOURNAL OF CROHNS & COLITIS
.
vol.
12
,
S80
-
S80
.
Ball JA, Clear AJ, Calaminici M, Stagg A, Lindsay J, Gribben JG, Davies J
(
2017
)
.
Human Gastro-Intestinal Graft-Versus-Host Disease Is Mediated By Retinoic Acid-Responsive CD8+ Effector T-Cells Under IL-23 Polarising Conditions
.
Blood
.
vol.
130
,
Gordon H, Hoti I, Lindsay JO, Stagg AJ
(
2017
)
.
Tu1908 Circulating Non-Classical Monocytes are Reduced in Patients with Active IBD but Increase after Vedolizumab: A Role for α4β7 in Myeloid Cell Recruitment to the Inflamed Intestine
.
Gastroenterology
.
vol.
152
,
s1003
-
s1004
.
MCCARTHY NE, Tyler CJ, Lindsay JO, Stagg AJ, Moser B, Eberl M
(
2017
)
.
Antigen-presenting human γδ T-cells promote intestinal CD4+ T-cell expression of IL-22 and mucosal release of calprotectin
.
Journal of Immunology
Giles EM, Stagg AJ
(
2017
)
.
Type 1 Interferon in the Human Intestine—A Co-ordinator of the Immune Response to the Microbiota
.
Inflammatory Bowel Diseases
vol.
23
,
(
4
)
524
-
533
.
Hedin CR, van der Gast CJ, Stagg AJ, Lindsay JO, Whelan K
(
2017
)
.
The gut microbiota of siblings offers insights into microbial pathogenesis of inflammatory bowel disease
.
Gut Microbes
vol.
8
,
(
4
)
359
-
365
.
Hoti I, McCarthy NE, Giles EM, Ayada I, Gordon H, Stagg AJ, Lindsay JO
(
2017
)
.
TNF alpha production by classical monocytes is poorly controlled by IL-10 in patients with IBD
.
JOURNAL OF CROHNS & COLITIS
.
Conference:
12th Congress of ECCO - European Crohn's and Colitis Organisation
(
Barcelona, Spain
)
from:
18/02/2017
to:
15/02/2017
,
vol.
11
,
S112
-
S112
.
Gordon H, Hoti I, Lindsay JO, Stagg A
(
2017
)
.
P053 Circulating non-classical monocytes are reduced in patients with active IBD but increase after vedolizumab: a role for α4β7 in myeloid cell recruitment to the inflamed intestine
.
Journal of Crohn's and Colitis
vol.
11
,
(
suppl_1
)
s104
-
s105
.
McCarthy N, Gordon H, Rahman S, Harrow P, Stagg A, Lindsay J
(
2017
)
.
P059 Mucosal inflammation promotes activation of circulating Vδ2+ T-cells in Crohn's disease
.
Journal of Crohn's and Colitis
.
vol.
11
,
s107
-
s107
.
Gordon H, Hoti I, Lindsay JO, Stagg A
(
2017
)
.
Circulating non-classical monocytes are reduced in patients with active IBD but increase after vedolizumab: a role for α4β7 in myeloid cell recruitment to the inflamed intestine
.
JOURNAL OF CROHNS & COLITIS
.
vol.
11
,
S104
-
S105
.
McCarthy N, Gordon H, Rahman S, Harrow P, Stagg A, Lindsay J
(
2017
)
.
Mucosal inflammation promotes activation of circulating Vd2+T-cells in Crohn's disease
.
JOURNAL OF CROHNS & COLITIS
.
vol.
11
,
S107
-
S107
.
Giles EM, Sanders TJ, McCarthy NE, Lung J, Pathak M, MacDonald TT, Lindsay JO, Stagg AJ
(
2016
)
.
Regulation of human intestinal T-cell responses by type 1 interferon-STAT1 signaling is disrupted in inflammatory bowel disease
.
Mucosal Immunology
vol.
10
,
(
1
)
184
-
193
.
Tyler C, McCarthy N, Moser B, Stagg A, Eberl M, Lindsay J
(
2016
)
.
Human intestinal Vδ2+T-cells acquire antigen-presenting potency upon exposure to microbial phosphoantigen: modulation by mucosal inflammation and vedolizumab therapy
.
JOURNAL OF CROHNS & COLITIS
vol.
10
,
S29
-
S29
.
Whitehouse A, Mushtaq N, McCarthy N, Stagg A, Grigg J
(
2016
)
.
Increased Airway Dendritic Cell Activation And Altered Subset Distribution In London Children Exposed To Higher Levels Of Pollution
.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
.
vol.
193
,
Anderson JL, Hedin CR, Benjamin JL, Koutsoumpas A, Ng SC, Hart AL, Forbes A, Stagg AJ et al.
(
2015
)
.
Dietary intake of inulin-type fructans in active and inactive Crohn’s disease and healthy controls: a case–control study
.
Journal of Crohn's and Colitis
vol.
9
,
(
11
)
1024
-
1031
.
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Hoti I, Ayada I, Baji V, Giles EM et al.
(
2015
)
.
Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease
.
Journal of Clinical Investigation
vol.
125
,
(
8
)
3215
-
3225
.
Hedin C, van der Gast CJ, Rogers GB, Cuthbertson L, McCartney S, Stagg AJ, Lindsay JO, Whelan K
(
2015
)
.
Siblings of patients with Crohn’s disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities
.
Gut
vol.
65
,
(
6
)
Beamish E, Pattisson C, Johnson J, Scott N, Bhowmick A, Stagg A, Rigby R
(
2015
)
.
Improving the Outcome of Stoma Reversal Surgery: Impact of Microflora
.
The FASEB Journal
.
vol.
29
,
Peiris M, Dogra H, de Almeida Araujo EJ, Stagg AJ, Blackshaw A
(
2015
)
.
Mo1718 CD11c Positive Dendritic Cells Express the Ion Channel TRPM8 in Human Colon, Which Regulates Immune Responses
.
Gastroenterology
vol.
148
,
(
4
)
Lahiri R, Derwa Y, Bashir Z, Giles E, Torrance H, O’Dwyer M, Owen H, O’Brien A et al.
(
2015
)
.
P0001 : Early monocyte dysfunction in patients who develop Systemic Inflammatory Response Syndrome (SIRS) and sepsis after hepatopancreaticobiliary surgery
.
Journal of Hepatology
.
vol.
62
,
s290
-
s291
.
Brugha R, Mushtaq N, McCarthy NE, Stagg AJ, Grigg J
(
2015
)
.
Respiratory tract dendritic cells in paediatric asthma
.
Clin Exp Allergy
vol.
45
,
(
3
)
624
-
631
.
Peiris M, Dogra H, Araujo EJDA, Stagg AJ, Blackshaw A
(
2015
)
.
CD11c Positive Dendritic Cells Express the Ion Channel TRPM8 in Human Colon, Which Regulates Immune Responses
.
GASTROENTEROLOGY
.
vol.
148
,
S693
-
S694
.
Lahiri R, Derwa Y, Bashir Z, Giles E, Torrance HD, Owen HC, O'Dwyer MJ, O'Brien A et al.
(
2015
)
.
Systemic Inflammatory Response Syndrome After Major Abdominal Surgery Predicted by Early Upregulation of TLR4 and TLR5
.
Annals of Surgery
vol.
263
,
(
5
)
1028
-
1037
.
Mann ER, Bernardo D, Ng SC, Rigby RJ, Al-Hassi HO, Landy J, Peake STC, Spranger H et al.
(
2014
)
.
Human Gut Dendritic Cells Drive Aberrant Gut-specific T-cell Responses in Ulcerative Colitis, Characterized by Increased IL-4 Production and Loss of IL-22 and IFNγ
.
Inflammatory Bowel Diseases
vol.
20
,
(
12
)
2299
-
2307
.
Vossenkämper A, Hundsrucker C, Page K, van Maurik A, Sanders TJ, Stagg AJ, Das L, MacDonald TT
(
2014
)
.
A CD3-specific antibody reduces cytokine production and alters phosphoprotein profiles in intestinal tissues from patients with inflammatory bowel disease
.
Gastroenterology
vol.
147
,
(
1
)
172
-
183
.
Hedin C, van der Gast C, Rogers G, McCartney S, Stagg A, Lindsay J, Whelan K
(
2014
)
.
OC-051 Siblings Of Crohn's Disease Patients Exhibit A Biologically Relevant Dysbiosis In The Mucosal Microbial Community: A 16s Rrna Gene Pyrosequencing Study
.
Gut
vol.
63 Suppl 1
,
Al-Hassi HO, Mann ER, Sanchez B, English NR, Peake STC, Landy J, Man R, Urdaci M et al.
(
2014
)
.
Altered human gut dendritic cell properties in ulcerative colitis are reversed by Lactobacillus plantarum extracellular encrypted peptide STp
.
Mol Nutr Food Res
vol.
58
,
(
5
)
1132
-
1143
.
Sanders TJ, McCarthy NE, Giles EM, Davidson KLM, Haltalli MLR, Hazell S, Lindsay JO, Stagg AJ
(
2014
)
.
Increased production of retinoic acid by intestinal macrophages contributes to their inflammatory phenotype in patients with Crohn's disease
.
Gastroenterology
vol.
146
,
(
5
)
Giles E, Pathak M, Sanders TJ, McCarthy NE, Sanderson IR, Thomas M, Lindsay JO, Stagg AJ
(
2014
)
.
Sa1778 Constitutive Type I Interferon, via STAT1 Activation, Selectively Promotes Regulatory T Cell Function in the Healthy Human Intestine, but Not in Inflammatory Bowel Disease
.
Gastroenterology
.
vol.
146
,
Hedin C, van der Gast C, Rogers G, McCartney S, Stagg AJ, Lindsay JO, Whelan K
(
2014
)
.
OP020 16S rRNA gene pyrosequencing indicate that siblings of Crohn's disease patients exhibit a biologically relevant dysbiosis in the mucosal microbiota communities
.
Journal of Crohn's and Colitis
vol.
8
,
(
Supplement_1
)
s11
-
s12
.
Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Taylor K, Prescott NJ, Murrells T et al.
(
2014
)
.
Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings
.
Gut
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Baji V, Giles EM, Wildemann M, Bashir Z et al.
(
2014
)
.
Colonic Vδ2+T-cells display elevated TNF production and reversible ablation by azathioprine therapy in Crohn's disease
.
IMMUNOLOGY
.
vol.
143
,
165
-
165
.
Giles E, Pathak M, Sanders TJ, McCarthy NE, Sanderson IR, Thomas M, Lindsay JO, Stagg AJ
(
2014
)
.
Constitutive Type I Interferon, via STAT1 Activation, Selectively Promotes Regulatory T Cell Function in the Healthy Human Intestine, but Not in Inflammatory Bowel Disease
.
GASTROENTEROLOGY
.
vol.
146
,
S293
-
S294
.
Giles E, Sanders TJ, McCarthy NE, Sanderson I, Lindsay J, MacDonald TT, Stagg AJ
(
2014
)
.
Constitutive Type I Interferon, via STAT1 activation, selectively promotes regulatory T cell function in the healthy human intestine, but not in IBD
.
IMMUNOLOGY
.
vol.
143
,
17
-
17
.
Brugha RE, Mushtaq N, Stagg A, Grigg J
(
2014
)
.
First Description Of Dendritic Cell Subsets In Induced Sputum From Children With Asthma
.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
.
vol.
189
,
Wildemann M, Mushtaq N, Sanders TJ, Zhou Z, Ezzati M, Grigg J, Stagg AJ
(
2014
)
.
Fossil Fuel And Biomass Derived Particulate Matter (pm) Induce Distinct Profiles Of Activation And Aryl Hydrocarbon Receptor (ahr) Signalling In Human Dendritic Cells
.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
.
vol.
189
,
Wildemann M, Mushtaq N, McCarthy N, Whitehouse A, Brugha R, Sanders T, Grigg J, Stagg A
(
2014
)
.
Fossil fuel derived ambient particulate matter (PM10) induces multiple pathways of activation in human dendritic cells
.
IMMUNOLOGY
vol.
143
,
99
-
99
.
Roberts SJ, Owen HC, Tam WL, Solie L, Van Cromphaut SJ, Van den Berghe G, Luyten FP
(
2013
)
.
Humanized Culture of Periosteal Progenitors in Allogeneic Serum Enhances Osteogenic Differentiation and In Vivo Bone Formation
.
Stem Cells Translational Medicine
vol.
3
,
(
2
)
218
-
228
.
McCarthy NE, Bashir Z, Vossenkämper A, Hedin CR, Giles EM, Bhattacharjee S, Brown SG, Sanders TJ et al.
(
2013
)
.
Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells
.
J Immunol
vol.
191
,
(
5
)
2752
-
2763
.
Vossenkämper A, Blair PA, Safinia N, Fraser LD, Das L, Sanders TJ, Stagg AJ, Sanderson JD et al.
(
2013
)
.
A role for gut-associated lymphoid tissue in shaping the human B cell repertoire
.
J Exp Med
vol.
210
,
(
9
)
1665
-
1674
.
Al-Hassi HO, Bernardo D, Murugananthan AU, Mann ER, English NR, Jones A, Kamm MA, Arebi N et al.
(
2013
)
.
A mechanistic role for leptin in human dendritic cell migration: differences between ileum and colon in health and Crohn's disease
.
Mucosal Immunol
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Hart AL, Kamm MA, Knight SC, Stagg AJ
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Prospective evaluation of intestinal homing memory T cells in ulcerative colitis
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496
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Burke F, Stagg AJ, Bedford PA, English N, Knight SC
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IL-10-producing B220+CD11c- APC in mouse spleen
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DNA derived from probiotic bacteria modulates human dendritic cell phenotype and function
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Hart AL, Al-Hassi HO, Kamm MA, Knight SC, Stagg AJ
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Stagg AJ, Hart AL, Knight SC, Kamm MA
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Interactions between dendritic cells and bacteria in the regulation of intestinal immunity
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BEST PRACT RES CL GA
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Stagg AJ, Hart AL, Knight SC, Kamm MA
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Microbial-gut interactions in health and disease. Interactions between dendritic cells and bacteria in the regulation of intestinal immunity
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Best Pract Res Clin Gastroenterol
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Hart AL, Al-Hassi HO, Kamm MA, Knight SC, Stagg AJ
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Toll like receptors 2 and 4 are upregulated on human lamina propria dendritic cells in intestinal inflammation
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GUT
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Hart AL, Kamm MA, Knight SC, Stagg AJ
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Quantitative and functional characteristics of intestinal-homing memory T cells: analysis of Crohn's disease patients and healthy controls
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CLIN EXP IMMUNOL
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BROWN KA, BEDFORD P, MACEY M, MCCARTHY DA, LEROY F, VORA AJ, STAGG AJ, DUMONDE DC et al.
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Human blood dendritic cells: binding to vascular endothelium and expression of adhesion molecules
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Clinical & Experimental Immunology
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107
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Stagg AJ, Hart AL, Knight SC, Kamm MA
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The dendritic cell: its role in intestinal inflammation and relationship with gut bacteria
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Gut
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52
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10
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Hart AL, Kamm MA, Knight SC, Stagg AJ
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The maturation and cytokine expression of human dendritic cells are differentially modulated by probiotic bacteria
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GUT
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Hart AL, Stagg AJ, Kamm MA
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Use of probiotics in the treatment of inflammatory bowel disease
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J Clin Gastroenterol
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Hart AL, Stagg AJ, Frame M, Graffner H, Glise H, Falk P, Kamm MA
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Review article: the role of the gut flora in health and disease, and its modification as therapy
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ALIMENT PHARM THERAP
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Stagg AJ, Kamm MA, Knight SC
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Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin
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Eur J Immunol
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Hart AL, Rigby R, Jones A, Kamm MA, Knight SC, Stagg AJ
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Circulating mucosal homing (beta 7+) memory T cells are decreased in number and display altered cytokine production in Crohn's disease
.
GUT
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50
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Rigby RJ, Hart AL, Westcott EDA, Kamm MA, Windsor A, Knight SC, Stagg AJ
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Identification of possible gut homing dendritic cells in peripheral blood by expression of B7 integrin
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GUT
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Stagg AJ, Kamm MA, Knight SC
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Intestinal dendritic cells increase T cell expression of alpha 4 beta 7 integrin
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GUT
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Rigby R, Kamm MA, Knight SC, Hart AL, Stagg AJ
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Pathogenic bacteria stimulate colonic dendritic cells to produce pro-inflammatory IL-12 while the response to probiotic bacteria is to produce anti-inflammatory IL-10
.
GUT
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Hart AL, Rigby R, Stagg AJ, Lammers K, Rizzello F, Gionchetti P, Campieri M, Knight SC et al.
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Probiotic bacteria stimulate natural killer (NK) cell activation and cytokine production, an early step in innate immunity
.
GUT
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Hart AL, Stagg AJ, Rigby R, Jones A, Lammers L, Rizzello F, Gionchetti P, Campieri M et al.
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Streptococcus faecium, a possible probiotic bacterium, but not Lactobacillus acidophilus or Escherichia coli (Nissle), decreases proinflammatory cytokine production (IFN-Gamma) by an IL-10 dependent mechanism
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GUT
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Jebbari H, Stagg AJ, Davidson RN, Knight SC
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Leishmania major promastigotes inhibit dendritic cell motility in vitro
.
Infect Immun
vol.
70
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1023
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Stagg AJ, Knight SC
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Antigen‐presenting Cells
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Encyclopedia of Life Sciences
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Wiley
Bell SJ, Rigby R, English N, Mann SD, Knight SC, Kamm MA, Stagg AJ
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2001
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Migration and maturation of human colonic dendritic cells
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J Immunol
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166
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Stagg AJ, Burke F, Hill S, Knight SC
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Isolation of mouse spleen dendritic cells
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Methods Mol Med
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64
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9
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22
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Konecny P, Stagg AJ, Jebbari H, English N, Davidson RN, Knight SC
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Murine dendritic cells internalize Leishmania major promastigotes, produce IL‐12 p40 and stimulate primary T cell proliferation in vitro
.
European Journal of Immunology
vol.
29
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6
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1803
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Stagg AJ, Tuffrey M, Woods C, Wunderink E, Knight SC
(
1998
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Protection against Ascending Infection of the Genital Tract by Chlamydia trachomatis Is Associated with Recruitment of Major Histocompatibility Complex Class II Antigen-Presenting Cells into Uterine Tissue
.
Infection and Immunity
vol.
66
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Müller K, Herner EB, Stagg A, Bendtzen K, Woo P
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Inflammatory cytokines and cytokine antagonists in whole blood cultures of patients with systemic juvenile chronic arthritis
.
Rheumatology
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37
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Stagg AJ
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Vaccines against Chlamydia: approaches and progress
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Trends in Molecular Medicine
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173
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Stagg AJ, Hughes RA, Keat AC, Elsley WA, Knight SC
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ANTIGEN-PRESENTING CELLS BUT NOT LYMPHOCYTES IN THE JOINT MAY INDICATE THE CAUSE OF REACTIVE ARTHRITIS
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Rheumatology
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Knight SC, Iqball S, Woods C, Stagg A, Ward ME, Tuffrey M
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A peptide of Chlamydia trachomatis shown to be a primary T-cell epitope in vitro induces cell-mediated immunity in vivo
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Immunology
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Stagg AJ, Breban M, Hammer RE, Knight SC, Taurog JD
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Defective Dendritic Cell (DC) Function in a HLA-B27 Transgenic Rat Model of Spondyloarthropathy (SpA)
.
Advances in Experimental Medicine and Biology
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Knight SC, Stagg AJ
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Current Opinion in Immunology
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Stagg AJ, Elsley WA, Pickett MA, Ward ME, Knight SC
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Primary human T-cell responses to the major outer membrane protein of Chlamydia trachomatis
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Immunology
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Stagg A, Knight SC, Webster AD, Farrant J
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Failure of primary and secondary T cell responses in common variable immunodeficiency
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Immunodeficiency
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Knight SC, Stagg A, Hill S, Fryer P, Griffiths S
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Development and Function of Dendritic Cells in Health and Disease
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Journal of Investigative Dermatology
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