Publications: Prof Yaohe Wang
Ning W, Qian X, Dunmall LC, Liu F, Guo Y, Li S, Song D, Liu D et al.
(
2024
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Non-secreting IL12 expressing oncolytic adenovirus Ad-TD-nsIL12 in recurrent high-grade glioma: a phase I trial
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Nature Communications
vol.
15
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1
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Jiang G, Wang Z, Cheng Z, Wang W, Lu S, Zhang Z, Anene CA, Khan F et al.
(
2024
)
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The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma
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Nature Communications
vol.
15
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(
1
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Pu D, Yao Y, Zhou C, Liu R, Wang Z, Liu Y, Wang D, Wang B et al.
(
2024
)
.
FMT rescues mice from DSS-induced colitis in a STING-dependent manner
.
Gut Microbes
vol.
16
,
(
1
)
Qian X, Ning W, Dunmall LC, Qu Y, Wang Y, Zhang H
(
2024
)
.
Treatment of intracranial inflammatory myofibroblastic tumor with PD-L1 inhibitor and novel oncolytic adenovirus Ad-TD-nsIL12: a case report and literature review
.
Frontiers in Immunology
vol.
15
,
Peng Y, Li Z, Zhang J, Dong Y, Zhang C, Dong Y, Zhai Y, Zheng H et al.
(
2024
)
.
Low‐Dose Colchicine Ameliorates Doxorubicin Cardiotoxicity Via Promoting Autolysosome Degradation
.
Journal of the American Heart Association
vol.
13
,
(
9
)
Wang L, Zhang L, Dunmall LC, Wang YY, Fan Z, Cheng Z, Wang Y
(
2024
)
.
The dilemmas and possible solutions for CAR-T cell therapy application in solid tumors
.
Cancer Letters
vol.
591
,
Lian X, Zhao X, Zhong J, Zhang C, Chu Y, Wang Y, Lu S, Wang Z
(
2023
)
.
A New HEK293 Cell with CR2 Region of E1A Gene Deletion Prevents the Emergence of Replication-Competent Adenovirus
.
Cancers
vol.
15
,
(
24
)
Yan W, Dunmall LSC, Lemoine NR, Wang Y, Wang Y, Wang P
(
2023
)
.
The capability of heterogeneous γδ T cells in cancer treatment
.
Frontiers in Immunology
vol.
14
,
Li S, Guo Y, Ning W, Chen Y, Xu J, Zhao C, Wang J, Qu Y et al.
(
2023
)
.
Oncolytic virus Ad-TD-nsIL-12 inhibits glioma growth and reprograms the tumor immune microenvironment
.
Life Sciences
vol.
336
,
Baleeiro RB, Liu P, Dunmall LSC, Di Gioia C, Nagano A, Cutmore L, Wang J, Chelala C et al.
(
2023
)
.
Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancer
.
Journal for ImmunoTherapy of Cancer
vol.
11
,
(
8
)
Wang L, Wang X, Wu Y, Wang J, Zhou W, Wang J, Guo H, Zhang N et al.
(
2023
)
.
A novel microenvironment regulated system CAR-T (MRS.CAR-T) for immunotherapeutic treatment of esophageal squamous carcinoma
.
Cancer Letters
vol.
568
,
Jia Y, Wang Y, Dunmall LSC, Lemoine NR, Wang P, Wang Y
(
2023
)
.
Syrian hamster as an ideal animal model for evaluation of cancer immunotherapy
.
Frontiers in Immunology
vol.
14
,
Wang L, Wu Y, Wang X, Wang J, Zhou W, Wang J, Guo H, Wu Y et al.
(
2023
)
.
A Novel Microenvironment Regulated System CAR-T (MRS.CAR-T) for Immunotherapeutic Treatment of Esophageal Squamous Carcinoma
.
MOLECULAR THERAPY
.
vol.
31
,
645
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646
.
Wong HH, Jiang G, Gangeswaran R, Wang P, Wang J, Yuan M, Wang H, Bhakta V et al.
(
2022
)
.
Modification of the Early Gene Enhancer-promoter Improves the Oncolytic Potency of Adenovirus 11
.
Molecular Therapy
vol.
31
,
(
1
)
Miao J, Lan T, Guo H, Wang J, Zhang G, Wang Z, Yang P, Li H et al.
(
2022
)
.
Characterization of SHARPIN knockout Syrian hamsters developed using CRISPR/Cas9 system
.
Animal Models and Experimental Medicine
vol.
6
,
(
5
)
489
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498
.
Zhang N, Wu Y, Wu Y, Wang L, Chen J, Wang X, Dunmall LSC, Cheng Z et al.
(
2022
)
.
Ferroptosis-Related Genes Are Potential Therapeutic Targets and the Model of These Genes Influences Overall Survival of NSCLC Patients
.
Cells
vol.
11
,
(
14
)
Lan T, Wang Y, Miao J, Guo H, Wang Z, Wang J, Zhang C, Yang P et al.
(
2022
)
.
Deoxythymidylate Kinase as a Promising Marker for Predicting Prognosis and Immune Cell Infiltration of Pan-cancer
.
Frontiers in Molecular Biosciences
vol.
9
,
Miao J, Xu H, Tian Y, Wang J, Tang W, Wang Y, Miao M, Liu J et al.
(
2022
)
.
COVID-19 Resulting in Potential Hearing Damage of Rodents
.
Chinese medicine and natural products
vol.
02
,
(
01
)
e28
-
e31
.
Wang Z, Cheng Z, Lu S, Dunmall LSC, Wang J, Guo Y, Wang Y
(
2022
)
.
Characterization of the Intra-tumoral B Cell Immunoglobulin Repertoire Is of Prognostic Value for Esophageal Squamous Cell Carcinoma
.
Frontiers in Immunology
vol.
13
,
Sun Y, Zhang Z, Zhang C, Zhang N, Wang P, Chu Y, Dunmall LSC, Lemoine NR et al.
(
2022
)
.
An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition
.
Molecular Therapy — Oncolytics
vol.
26
,
105
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119
.
Wang L, Dunmall LSC, Cheng Z, Wang Y
(
2022
)
.
Remodeling the tumor microenvironment by oncolytic viruses: beyond oncolysis of tumor cells for cancer treatment
.
Journal for ImmunoTherapy of Cancer
vol.
10
,
(
5
)
Xu L, Wang J, Zhang D, Song L, Wu H, Wang J, Miao J, Guo H et al.
(
2022
)
.
The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context
.
Cell & Bioscience
vol.
12
,
(
1
)
Baleeiro RB, Bouwens CJ, Liu P, Di Gioia C, Dunmall LSC, Nagano A, Gangeswaran R, Chelala C et al.
(
2022
)
.
MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy
.
OncoImmunology
vol.
11
,
(
1
)
Baleeiro RB, Dunmall LSC, Liu P, Lu S, Lone Y, Lemoine NR, Wang Y
(
2022
)
.
Optimized Anchor-Modified Peptides Targeting Mutated RAS Are Promising Candidates for Immunotherapy
.
Frontiers in Immunology
vol.
13
,
Cao D, Song Q, Li J, Dunmall LSC, Jiang Y, Qin B, Wang J, Guo H et al.
(
2022
)
.
Redirecting anti-Vaccinia virus T cell immunity for cancer treatment by AAV-mediated delivery of the VV B8R gene
.
Molecular Therapy — Oncolytics
vol.
25
,
264
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275
.
Zhang X, Wang M, Feng J, Qin B, Zhang C, Zhu C, Liu W, Wang Y et al.
(
2022
)
.
Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer
.
Journal of Nanobiotechnology
vol.
20
,
(
1
)
Zhang X, Qin B, Wang M, Feng J, Zhang C, Zhu C, He S, Liu H et al.
(
2022
)
.
Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment
.
International Journal of Nanomedicine
vol.
17
,
953
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967
.
Miao J, Li R, Van Wettere AJ, Guo H, Tabaran A-F, O'Sullivan MG, Carlson T, Scott PM et al.
(
2021
)
.
Cancer spectrum in TP53-deficient golden Syrian hamsters: A new model for Li-Fraumeni syndrome
.
Journal of Carcinogenesis
vol.
20
,
(
1
)
Lu S, Zhang Z, Du P, Chard LS, Yan W, El Khouri M, Wang Z, Zhang Z et al.
(
2021
)
.
Correction: A Virus-infected, Reprogrammed Somatic Cell–derived Tumor Cell (VIReST) Vaccination Regime can Prevent Initiation and Progression of Pancreatic Cancer
.
Clinical Cancer Research
vol.
27
,
(
9
)
2663
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2663
.
Lan T, Xue X, Dunmall LC, Miao J, Wang Y
(
2021
)
.
Patient-derived xenograft: a developing tool for screening biomarkers and potential therapeutic targets for human esophageal cancers
.
Aging
vol.
13
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8
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12273
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12293
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Xue X, Shi J, Xu H, Qin Y, Yang Z, Feng S, Liu D, Jian L et al.
(
2021
)
.
Dynamics of binding ability prediction between spike protein and human ACE2 reveals the adaptive strategy of SARS-CoV-2 in humans
.
Scientific Reports
vol.
11
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(
1
)
Marelli G, Dunmall LSC, Yuan M, Di Gioia C, Miao J, Cheng Z, Zhang Z, Liu P et al.
(
2021
)
.
A systemically deliverable Vaccinia virus with increased capacity for intertumoral and intratumoral spread effectively treats pancreatic cancer
.
Journal for ImmunoTherapy of Cancer
vol.
9
,
(
1
)
Wang N, Wang J, Zhang Z, Cao H, Yan W, Chu Y, Dunmall LSC, Wang Y
(
2020
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.
A novel vaccinia virus enhances anti-tumor efficacy and promotes a long-term anti-tumor response in a murine model of colorectal cancer
.
Molecular Therapy — Oncolytics
vol.
20
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71
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81
.
Zhang Z, Zhang C, Miao J, Wang Z, Wang Z, Cheng Z, Wang P, Dunmall LSC et al.
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2020
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A Tumor-Targeted Replicating Oncolytic Adenovirus Ad-TD-nsIL12 as a Promising Therapeutic Agent for Human Esophageal Squamous Cell Carcinoma
.
Cells
vol.
9
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11
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Fang G, Miao J, Peng Y, Zhai Y, Wang C, Zhao X, Wang Y, Dong J
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2020
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Identification of Three FBN1 Mutations in Chinese Patients with Typical or Incomplete Marfan Syndrome by Whole-Exome Sequencing
.
Cardiovascular Innovations and Applications
vol.
5
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(
1
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19
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26
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Miao J-X, Wang J-Y, Li H-Z, Guo H-R, Dunmall LSC, Zhang Z-X, Cheng Z-G, Gao D-L et al.
(
2020
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.
Promising xenograft animal model recapitulating the features of human pancreatic cancer
.
World Journal of Gastroenterology
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26
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32
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4802
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4816
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Zhang Z, Lu S, Dunmall LSC, Wang Z, Cheng Z, Zhang Z, Yan W, Chu Y et al.
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2020
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Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime
.
Frontiers in Immunology
vol.
11
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Zhai Y, Miao J, Peng Y, Fang G, Wang C, Wang Y, Zhao X, Dong J
(
2020
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Discovery of Digenic Mutation, KCNH2 c.1898A >C and JUP c.916dupA, in a Chinese Family with Long QT Syndrome via Whole-Exome Sequencing
.
Cardiovascular Innovations and Applications
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4
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4
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257
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267
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Peng Y, Miao J, Zhai Y, Fang G, Wang C, Wang Y, Zhao X, Dong J
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2020
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Identification of Novel TTN Mutations in Three Chinese Familial Dilated Cardiomyopathy Pedigrees by Whole Exome Sequencing
.
Cardiovascular Innovations and Applications
vol.
4
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(
4
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229
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237
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(
2020
)
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Correction: A new oncolytic Vaccinia virus augments antitumor immune responses to prevent tumor recurrence and metastasis after surgery
.
Journal for ImmunoTherapy of Cancer
vol.
8
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(
1
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Ahmed J, Chard LS, Yuan M, Wang J, Howells A, Li Y, Li H, Zhang Z et al.
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2020
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A new oncolytic Vaccinia virus augments antitumor immune responses to prevent tumor recurrence and metastasis after surgery
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Journal for ImmunoTherapy of Cancer
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8
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1
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Hu X, Mao C, Hu Z, Zhang Z, Zhang S, Yang Z, Fan Y, Fan L et al.
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2020
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Association analysis of 15 GWAS-linked loci with Parkinson’s disease in Chinese Han population
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Neuroscience Letters
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725
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Ferguson MS, Chard Dunmall LS, Gangeswaran R, Marelli G, Tysome JR, Burns E, Whitehead MA, Aksoy E et al.
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2020
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Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus
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Molecular Therapy
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28
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5
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1263
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1275
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Cutmore LC, Brown NF, Raj D, Chauduri S, Wang P, Maher J, Wang Y, Lemoine NR et al.
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2020
)
.
Pancreatic Cancer UK Grand Challenge: Developments and challenges for effective CAR T cell therapy for pancreatic ductal adenocarcinoma
.
Pancreatology
Yu S, Yin J-J, Miao J-X, Li S-G, Huang C-Z, Huang N, Fan T-L, Li X-N et al.
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2020
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Activation of NLRP3 inflammasome promotes the proliferation and migration of esophageal squamous cell carcinoma
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Oncology Reports
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43
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4
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1113
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1124
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Lu S, Zhang Z, Du P, Chard LS, Yan W, Khouri ME, Wang Z, Zhang Z et al.
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2020
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A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer
.
Clinical Cancer Research
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26
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2
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465
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476
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Li R, Ying B, Liu Y, Spencer JF, Miao J, Tollefson AE, Brien JD, Wang Y et al.
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2020
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Generation and characterization of an IL2RG knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients
.
Disease Models & Mechanisms
Miao J, Chard LS, Wang Z, Wang Y
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2019
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Syrian Hamster as an Animal Model for the Study on Infectious Diseases
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Frontiers in Immunology
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Zhang S, Hu Z-W, Luo H-Y, Mao C-Y, Tang M-B, Li Y-S, Song B, Wang Y-H et al.
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AAV/BBB-Mediated Gene Transfer of CHIP Attenuates Brain Injury Following Experimental Intracerebral Hemorrhage
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296
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Hallden G, Wang Y, Wong H-H, Lemoine NR
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ONCOLYTIC ADENOVIRUSES FOR CANCER GENE THERAPY
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Advanced Textbook on Gene Transfer, Gene Therapy and Genetic Pharmacology
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World Scientific Publishing
Di Gioia C, Yuan M, Wang Y
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Vaccinia Virus Genome Editing Using CRISPR
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Methods in Molecular Biology
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Qin S-R, Zhao Q, Cheng Z-G, Zhang D-X, Zhang K-K, Su L-X, Fan H-J, Wang Y-H et al.
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Rare earth-functionalized nanodiamonds for dual-modal imaging and drug delivery
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Mao C, Wang H, Luo H, Zhang S, Xu H, Zhang S, Rosenblum J, Wang Z et al.
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CHCHD10 is involved in the development of Parkinson's disease caused by CHCHD2 loss-of-function mutation p.T61I
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Neurobiology of Aging
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Shi C-H, Rubel C, Soss SE, Sanchez-Hodge R, Zhang S, Madrigal SC, Ravi S, McDonough H et al.
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Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16
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Yan J, Du P, Jia Y, Chang Z, Gan S, Xu X, Wang Y, Qin Y et al.
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Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling [Retraction]
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Abstract 1975: Disulfiram targets hypoxia-induced cancer stem cells and reverses chemoresistance in non-small cell lung cancer
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Characterization of an N-Terminal Non-Core Domain of RAG1 Gene Disrupted Syrian Hamster Model Generated by CRISPR Cas9
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Oncolytic Viral Therapy and the Immune System: A Double-Edged Sword Against Cancer
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Li R, Miao J, Fan Z, Song S, Kong I-K, Wang Y, Wang Z
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Production of Genetically Engineered Golden Syrian Hamsters by Pronuclear Injection of the CRISPR/Cas9 Complex
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A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
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SMPD1 variants in Chinese Han patients with sporadic Parkinson's disease
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Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture
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Exome capture sequencing identifies a novel CCM1 mutation in a Chinese family with multiple cerebral cavernous malformations
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