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Research

Publications: Dr David Wareham

McDonald NL, Wareham DW, Bean DC ( 2024 ) . Aeromonas and mcr–3: A Critical Juncture for Transferable Polymyxin Resistance in Gram-Negative Bacteria . Pathogens vol. 13 , ( 11 )
Henriksen AS, Arena F, Attwood M, Canton R, Gatermann S, Naas T, Morrissey I, Longshaw C et al. ( 2024 ) . In vitro activity of cefiderocol against European Enterobacterales, including isolates resistant to meropenem and recentβ-lactam/β-lactamase inhibitor combinations . Microbiology Spectrum vol. 12 , ( 8 ) e04181 - e04123 .
Wareham D, Melzer M ( 2024 ) . Clinical outcomes in OPAT patients treated with ceftriaxone 4 g and ceftazidime 6 g extended interval dosing regimens . JAC-Antimicrobial Resistance vol. 6 , ( 3 )
Henriksen AS, Jeannot K, Oliver A, Perry JD, Pletz MW, Stefani S, Morrissey I, Longshaw C et al. ( 2024 ) . In vitro activity of cefiderocol against European Pseudomonas aeruginosa and Acinetobacter spp., including isolates resistant to meropenem and recent β-lactam/β-lactamase inhibitor combinations . Microbiology Spectrum vol. 12 , ( 4 ) e03836 - e03823 .
Amulele AV, Ong’ayo G, Arara AM, Machanja EW, Etyang A, Aliyan NA, Wareham DW, Berkley JA et al. ( 2023 ) . Recurrent spontaneous Escherichia coli meningitis in an adult: a case report . JAC-Antimicrobial Resistance vol. 5 , ( 2 )
Stevenson DR, Cherian BP, Kinzig M, Sörgel F, Wareham DW ( 2022 ) . Intravenous cefiderocol for neurosurgical meningitis from an extensively drug-resistant New-Delhi metallo-β-lactamase-producing Pseudomonas aeruginosa strain . Journal of Global Antimicrobial Resistance vol. 32 , 29 - 30 .
Bean DC, Wareham DW ( 2022 ) . Corrigendum to ‘Draft genome sequence of a multidrug-resistant Pseudomonas aeruginosa producing blaSIM metallo-β-lactamase: London, UK’ [Journal of Global Antimicrobial Resistance 29 (2022) 222-224] . Journal of Global Antimicrobial Resistance vol. 30 ,
Ledda A, Cummins M, Shaw LP, Jauneikaite E, Cole K, Lasalle F, Barry D, Turton J et al. ( 2022 ) . Hospital outbreak of carbapenem-resistant Enterobacterales associated with a bla OXA-48 plasmid carried mostly by Escherichia coli ST399 . Microbial Genomics vol. 8 , ( 4 )
Bean DC, Wareham DW ( 2022 ) . Draft genome sequence of a multidrug-resistant Pseudomonas aeruginosa producing bla SIM metallo-β-lactamase: London, UK . Journal of Global Antimicrobial Resistance vol. 29 , 222 - 224 .
Wareham D, Attwood M, Casey AL, Coyne M, Hughes D, Lister M, Nahl J, Perry JD et al. ( 2022 ) . P43 In vitro activity of cefiderocol and comparators against Gram-negative pathogens: ARTEMIS study in the UK . JAC-Antimicrobial Resistance vol. 4 , ( Supplement_1 )
Stevenson DR, Cherian BP, Kinzig M, Sörgel F, Wareham DW ( 2022 ) . P44 Nosocomial neurosurgical meningitis due to XDR Pseudomonas aeruginosa: clinical experience with cefiderocol . JAC-Antimicrobial Resistance vol. 4 , ( Supplement_1 )
McCarthy RR, Larrouy-Maumus GJ, Meiqi Tan MGC, Wareham DW ( 2021 ) . Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii . Microbial Pathogenesis , vol. 1313 , Springer Nature
Shi Y, Wareham DW, Yuan Y, Deng X, Mata A, Azevedo HS ( 2021 ) . Polymyxin B-Triggered Assembly of Peptide Hydrogels for Localized and Sustained Release of Combined Antimicrobial Therapy . Advanced Healthcare Materials
Mabayoje DA, NicFhogartaigh C, Cherian BP, Tan MGM, Wareham DW ( 2021 ) . Compassionate use of cefiderocol for carbapenem-resistant Acinetobacter baumannii prosthetic joint infection . JAC-Antimicrobial Resistance vol. 3 , ( Supplement_1 ) i21 - i24 .
Montag D, Delgado CA, Quispe C, Wareham D, Gallo V, Sanchez-Choy J, Sánchez V, Anaya R et al. ( 2021 ) . Launching of the Anaemia Research Peruvian Cohort (ARPEC): a multicentre birth cohort project to explore the iron adaptive homeostasis, infant growth and development in three Peruvian regions . BMJ Open vol. 11 , ( 5 )
Shi Y, Wareham DW, Phee LM, Azevedo HS ( 2020 ) . CHAPTER 12 Self-assembled Peptide Nanostructures for Antibacterial Applications . Peptide-based Biomaterials , Royal Society of Chemistry (RSC)
Phee L, Wareham D ( 2020 ) . Detecting Antimicrobial Resistance . Tutorial Topics in Infection for the Combined Infection Training Programme , Oxford University Press (OUP)
Lampejo T, Cherian BP, Tan MGM, Wareham DW ( 2020 ) . Cefiderocol in the treatment of systemic carbapenemase-producing multidrug-resistant Klebsiella pneumoniae infection . Journal of Global Antimicrobial Resistance vol. 23 , 338 - 339 .
Bean DC, Wigmore SM, Momin MHFA, Wareham DW ( 2020 ) . Polymyxin Resistant Bacteria in Australian Poultry . Frontiers in Sustainable Food Systems vol. 4 ,
Wareham DW, Momin MHFA, Phee LM, Hornsey M, Standing JF ( 2020 ) . Cefepime/sulbactam as an enhanced antimicrobial combination therapy for the treatment of MDR Gram-negative infections—authors’ response . Journal of Antimicrobial Chemotherapy vol. 75 , ( 9 ) 2713 - 2713 .
Maslova E, Shi Y, Sjöberg F, Azevedo HS, Wareham DW, McCarthy RR ( 2020 ) . An Invertebrate Burn Wound Model That Recapitulates the Hallmarks of Burn Trauma and Infection Seen in Mammalian Models . Frontiers in Microbiology vol. 11 ,
Day MJ, Hopkins KL, Wareham DW, Toleman MA, Elviss N, Randall L, Teale C, Cleary P et al. ( 2019 ) . Extended-spectrum β-lactamase-producing Escherichia coli in human-derived and foodchain-derived samples from England, Wales, and Scotland: an epidemiological surveillance and typing study . The Lancet Infectious Diseases vol. 19 , ( 12 ) 1325 - 1335 .
Wareham DW, Momin MHFA, Phee LM, Hornsey M, Standing JF ( 2019 ) . Cefepime/sulbactam as an enhanced antimicrobial combination therapy for the treatment of MDR Gram-negative infections . Journal of Antimicrobial Chemotherapy vol. 75 , ( 1 ) 135 - 139 .
Abdul Momin MHF, Liakopoulos A, Bean DC, Phee LM, Wareham DW ( 2019 ) . A novel plasmid-mediated polymyxin resistance determinant (mcr-1.8) in Escherichia coli recovered from broiler chickens in Brunei Darussalam . J Antimicrob Chemother
Bean DC, Agarwal A, Cherian BP, Wareham DW ( 2019 ) . Hypermucoviscous polymyxin-resistant Klebsiella pneumoniae from Kolkata, India: Genomic and phenotypic analysis . Journal of Global Antimicrobial Resistance vol. 17 , 1 - 2 .
Phee LM, Kloprogge F, Morris R, Barrett J, Wareham DW, Standing JF ( 2019 ) . Pharmacokinetic-pharmacodynamic modelling to investigate in vitro synergy between colistin and fusidic acid against MDR Acinetobacter baumannii . Journal of Antimicrobial Chemotherapy vol. 74 , ( 4 ) 961 - 969 .
Hornsey M, Betts JW, Mehat JW, Wareham DW, van Vliet AHM, Woodward MJ, La Ragione RM ( 2018 ) . Characterization of a colistin-resistant Avian Pathogenic Escherichia coli ST69 isolate recovered from a broiler chicken in Germany . J Med Microbiol vol. 68 , ( 1 ) 111 - 114 .
Livermore DM, Day M, Cleary P, Hopkins KL, Toleman MA, Wareham DW, Wiuff C, Doumith M et al. ( 2018 ) . OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli . Journal of Antimicrobial Chemotherapy vol. 74 , ( 2 ) 326 - 333 .
Wareham DW, Phee LM, Abdul Momin MHF ( 2018 ) . Direct detection of carbapenem resistance determinants in clinical specimens using immunochromatographic lateral flow devices . J Antimicrob Chemother vol. 73 , ( 7 ) 1997 - 1998 .
WAREHAM DW ( 2018 ) . Effects of In vivo Emergent Tigecycline Resistance on the Pathogenic Potential of Acinetobacter baumannii . Scientific Reports
Betts JW, Abdul Momin HF, Phee LM, Wareham DW ( 2018 ) . Comparative activity of tedizolid and glycopeptide combination therapies for the treatment of Staphylococcus aureus infections: an in vitro and in vivo evaluation against strains with reduced susceptibility to glycopeptides . J Med Microbiol vol. 67 , ( 2 ) 265 - 271 .
Ruszczak A, Scheler O, Jankowski P, Horka M, Derzsi L, Wareham D, Garstecki P ( 2018 ) . Compatibility of droplet systems with antibiotic susceptibility testing . 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 . vol. 3 , 1458 - 1461 .
Woodford N, Xu-McCrae L, Mushtaq S, Wu HHT, Ellington MJ, Lancaster O, Davies F, Donaldson H et al. ( 2017 ) . Prevalence of carbapenem resistance and carbapenemase production among Enterobacteriaceae isolated from urine in the UK: results of the UK infection-Carbapenem Resistance Evaluation Surveillance Trial (iCREST-UK) . Journal of Antimicrobial Chemotherapy vol. 73 , ( 3 ) 698 - 702 .
Abdul Momin MHF, Bean DC, Hendriksen RS, Haenni M, Phee LM, Wareham DW ( 2017 ) . CHROMagar COL-APSE: a selective bacterial culture medium for the isolation and differentiation of colistin-resistant Gram-negative pathogens . J Med Microbiol vol. 66 , ( 11 ) 1554 - 1561 .
Ciesielczuk H, Phee LM, Dolphin H, Wilks M, Cherian BP, Wareham DW ( 2017 ) . Optimal detection of carbapenemase-producing Enterobacteriaceae from rectal samples: a role for enrichment? . Journal of Hospital Infection vol. 98 , ( 3 ) 270 - 274 .
WAREHAM DW ( 2017 ) . A Drug to Consider Re-purposing in the Targeted Treatment of Multi-drug Resistant Bacterial Infections? . Journal of Laboratory and Precision Medicine vol. 2 , ( 49 )
WAREHAM DW ( 2017 ) . Detection of Polymyxin Resistant Escherichai coli from Broiler Chickens in Brunei Darussalam: use of a Novel Chromogenic Bacterial Culture Media (CHROMagar COL-APSE) . Conference: 15th International Congress of Bacteriology and Applied Microbiology
Abdul Momin MHF, Liakopoulos A, Wareham DW ( 2017 ) . Draft Genome Sequence of a Multidrug-Resistant Sequence Type 231 Outbreak-Associated Clone of Klebsiella pneumoniae, KP41-2015, Producing OXA-232 Carbapenemase . Genome Announc vol. 5 , ( 27 )
Betts JW, Hornsey M, Wareham DW, La Ragione RM ( 2017 ) . In vitro and In vivo Activity of Theaflavin-Epicatechin Combinations versus Multidrug-Resistant Acinetobacter baumannii . Infect Dis Ther
Abdul Momin MHF, Liakopoulos A, Phee LM, Wareham DW ( 2017 ) . Emergence and nosocomial spread of carbapenem-resistant OXA-232-producing Klebsiella pneumoniae in Brunei Darussalam . J Glob Antimicrob Resist vol. 9 , 96 - 99 .
Tängdén T, Ramos Martín V, Felton TW, Nielsen EI, Marchand S, Brüggemann RJ, Bulitta JB, Bassetti M et al. ( 2017 ) . The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections . Intensive Care Medicine vol. 43 , ( 7 ) 1021 - 1032 .
Cahill ST, Cain R, Wang DY, Lohans CT, Wareham DW, Oswin HP, Mohammed J, Spencer J et al. ( 2017 ) . Cyclic Boronates Inhibit All Classes of β-Lactamases . Antimicrobial Agents and Chemotherapy vol. 61 , ( 4 ) 10.1128/aac.02260 - 10.1128/aac.02216 .
Wareham DW, Abdul Momin MHF ( 2017 ) . Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay . J Clin Microbiol vol. 55 , ( 4 ) 1223 - 1225 .
Liakopoulos A, Oikonomou O, Wareham DW ( 2017 ) . Draft Genome Sequence of Providencia stuartii PS71, a Multidrug-Resistant Strain Associated with Nosocomial Infections in Greece . Genome Announc vol. 5 , ( 12 )
Lüthje P, Pranada AB, Carruthers-Lay D, Desjardins M, Gaillot O, Wareham D, Ciesielczuk H, Özenci V ( 2017 ) . Identification of microorganisms grown on chromogenic media by MALDI-TOF MS . Journal of Microbiological Methods vol. 136 , 17 - 20 .
WAREHAM DW ( 2017 ) . Draft Genome Sequence of a Canine Isolate of Methicillin-Resistant Staphylococcus haemolyticus . Genome Announcements
Bean DC, Wigmore SM, Wareham DW ( 2017 ) . Draft Genome Sequence of Staphylococcus cohnii subsp. urealyticus Isolated from a Healthy Dog . Genome Announc vol. 5 , ( 7 )
Li G-B, Abboud MI, Brem J, Someya H, Lohans CT, Yang S-Y, Spencer J, Wareham DW et al. ( 2016 ) . NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors . Chem Sci vol. 8 , ( 2 ) 928 - 937 .
Oikonomou O, Liakopoulos A, Phee LM, Betts J, Mevius D, Wareham DW ( 2016 ) . Providencia stuartii Isolates from Greece: Co-Carriage of Cephalosporin ( bla SHV-5 , bla VEB-1 ), Carbapenem ( bla VIM-1 ), and Aminoglycoside ( rmtB ) Resistance Determinants by a Multidrug-Resistant Outbreak Clone . Microbial Drug Resistance vol. 22 , ( 5 ) 379 - 386 .
Betts JW, Sharili AS, La Ragione RM, Wareham DW ( 2016 ) . In Vitro Antibacterial Activity of Curcumin–Polymyxin B Combinations against Multidrug-Resistant Bacteria Associated with Traumatic Wound Infections . Journal of Natural Products vol. 79 , ( 6 ) 1702 - 1706 .
Ciesielczuk H, Jenkins C, Chattaway M, Doumith M, Hope R, Woodford N, Wareham DW ( 2016 ) . Trends in ExPEC serogroups in the UK and their significance . European Journal of Clinical Microbiology & Infectious Diseases
WAREHAM DW ( 2016 ) . Co-carriage of Plasmid-Mediated Fosfomycin Resistance Determinants (fos) by Carbapenem Resistant Enterobacteriaceae in the United Kingdom . Conference: ASM Microbe 2016 ( Boston ) from: 16/06/2016 to: 20/06/2016 ,
Martínez-Guitián M, Vázquez-Ucha JC, Odingo J, Parish T, Poza M, Waite RD, Bou G, Wareham DW et al. ( 2016 ) . Synergy between Colistin and the Signal Peptidase Inhibitor MD3 Is Dependent on the Mechanism of Colistin Resistance in Acinetobacter baumannii . Antimicrobial Agents and Chemotherapy vol. 60 , ( 7 ) 4375 - 4379 .
Millar MR, Seale J, Turton J, Wilks M, Costeloe K, Woodford N, Juszczak E, Whiley A et al. ( 2016 ) . ESBL-producing Enterobacteriaceae in 24 neonatal units and associated networks in the south of England: no clustering of ESBL-producing Escherichia coli in units or networks . Journal of Antimicrobial Chemotherapy vol. 71 , ( 5 ) 1174 - 1177 .
Betts JW, Phee LM, Momin MHFA, Umland K-D, Brem J, Schofield CJ, Wareham DW ( 2016 ) . In vitro and in vivo activity of ML302F: a thioenolate inhibitor of VIM-subfamily metallo β-lactamses . RSC Medicinal Chemistry vol. 7 , ( 1 ) 190 - 193 .
Betts JW, Phee LM, Wareham DW ( 2015 ) . Rifaximin combined with polymyxins: A potential regimen for selective decontamination of multidrug-resistant bacteria in the digestive tract? . Journal of Global Antimicrobial Resistance vol. 4 , 11 - 15 .
Wareham DW, Shah R, Betts JW, Phee LM, Momin MHFA ( 2015 ) . Evaluation of an Immunochromatographic Lateral Flow Assay (OXA-48 K-SeT) for Rapid Detection of OXA-48-Like Carbapenemases in Enterobacteriaceae . Journal of Clinical Microbiology vol. 54 , ( 2 ) 471 - 473 .
Ciesielczuk H, Doumith M, Hope R, Woodford N, Wareham DW ( 2015 ) . Characterization of the extra-intestinal pathogenic Escherichia coli ST131 clone among isolates recovered from urinary and bloodstream infections in the United Kingdom . Journal of Medical Microbiology vol. 64 , ( 12 ) 1496 - 1503 .
Niebel M, Quick J, Prieto AMG, Hill RLR, Pike R, Huber D, David M, Hornsey M et al. ( 2015 ) . Deletions in a ribosomal protein-coding gene are associated with tigecycline resistance in Enterococcus faecium . International Journal of Antimicrobial Agents vol. 46 , ( 5 ) 572 - 575 .
Betts JW, Sharili AS, Phee LM, Wareham DW ( 2015 ) . In Vitro Activity of Epigallocatechin Gallate and Quercetin Alone and in Combination versus Clinical Isolates of Methicillin-Resistant Staphylococcus aureus . Journal of Natural Products vol. 78 , ( 8 ) 2145 - 2148 .
WAREHAM DW, Phee LM, Betts JW ( 2015 ) . Colistin and Fusidic acid: A Novel Potent Synergistic Combination for the Treatment of Acinetobacter baumannii Infection .
Ciesielczuk H, Betts J, Phee L, Doumith M, Hope R, Woodford N, Wareham DW ( 2015 ) . Comparative virulence of urinary and bloodstream isolates of extra-intestinal pathogenic Escherichia coli in a Galleria mellonella model . Virulence vol. 6 , ( 2 ) 145 - 151 .
Makena A, Brem J, Pfeffer I, Geffen REJ, Wilkins SE, Tarhonskaya H, Flashman E, Phee LM et al. ( 2015 ) . Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability . J Antimicrob Chemother vol. 70 , ( 2 ) 463 - 469 .
Phee L, Bharathan B, Wareham DW ( 2014 ) . 481Successful Treatment of Multi-drug Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia with a Novel Colistin and Fusidic Acid Combination Therapy . Open Forum Infectious Diseases vol. 1 , ( suppl_1 ) s179 - s179 .
Personne Y, Curtis MA, Wareham DW, Waite RD ( 2014 ) . Activity of the type I signal peptidase inhibitor MD3 against multidrug-resistant Gram-negative bacteria alone and in combination with colistin . J Antimicrob Chemother vol. 69 , ( 12 ) 3236 - 3243 .
Betts JW, Phee LM, Woodford N, Wareham DW ( 2014 ) . Activity of colistin in combination with tigecycline or rifampicin against multidrug-resistant Stenotrophomonas maltophilia . Eur J Clin Microbiol Infect Dis vol. 33 , ( 9 ) 1565 - 1572 .
Betts JW, Wareham DW ( 2014 ) . In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii . BMC Microbiol vol. 14 ,
Betts JW, Phee LM, Hornsey M, Woodford N, Wareham DW ( 2014 ) . In vitro and in vivo activities of tigecycline-colistin combination therapies against carbapenem-resistant Enterobacteriaceae . Antimicrob Agents Chemother vol. 58 , ( 6 ) 3541 - 3546 .
Cheng F, Betts JW, Kelly SM, Wareham DW, Kornherr A, Dumestre F, Schaller J, Heinze T ( 2014 ) . Whiter, brighter, and more stable cellulose paper coated with antibacterial carboxymethyl starch stabilized ZnO nanoparticles . Journal of Materials Chemistry B vol. 2 , ( 20 ) 3057 - 3064 .
Cheng F, BETTS JW, Kelly SM, Wareham DW, Kornherr A, Dumestre F, Schaller J, Heinze T ( 2014 ) . Whiter, brighter, and more stable cellulose paper coated with antibacterial carboxymethyl starch stabilized ZnO nanoparticles . Journals of Materials Chemistry B: Materials for Biology and Medicine vol. 2 , 3057 - 3064 .
Woodford N, Wareham DW, Guerra B, Teale C ( 2014 ) . Carbapenemase-producing enterobacteriaceae and non-enterobacteriaceae from animals and the environment: An emerging public health risk of our own making? . Journal of Antimicrobial Chemotherapy vol. 69 , ( 2 ) 287 - 291 .
Ciesielczuk H, Hornsey M, Choi V, Woodford N, Wareham DW ( 2013 ) . Development and evaluation of a multiplex PCR for eight plasmid-mediated quinolone-resistance determinants . Journal of Medical Microbiology vol. 62 , ( PART 12 ) 1823 - 1827 .
Ciesielczuk H, Hornsey M, Choi V, Woodford N, Wareham DW ( 2013 ) . Development and evaluation of a multiplex PCR for eight plasmid-mediated quinolone-resistance determinants . J Med Microbiol vol. 62 , ( Pt 12 ) 1823 - 1827 .
Phee L, Hornsey M, Wareham DW ( 2013 ) . In vitro activity of daptomycin in combination with low-dose colistin against a diverse collection of Gram-negative bacterial pathogens . European Journal of Clinical Microbiology and Infectious Diseases vol. 32 , ( 10 ) 1291 - 1294 .
Phee L, Hornsey M, Wareham DW ( 2013 ) . In vitro activity of daptomycin in combination with low-dose colistin against a diverse collection of Gram-negative bacterial pathogens . Eur J Clin Microbiol Infect Dis vol. 32 , ( 10 ) 1291 - 1294 .
Hornsey M, Phee L, Stubbings W, Wareham DW ( 2013 ) . In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens . International Journal of Antimicrobial Agents vol. 42 , ( 4 ) 343 - 346 .
Betts JW, Wareham DW, Haswell SJ, Kelly SM ( 2013 ) . Antifungal synergy of theaflavin and epicatechin combinations against Candida albicans . J Microbiol Biotechnol vol. 23 , ( 9 ) 1322 - 1326 .
Wareham D, Phee L, Hornsey M ( 2013 ) . P317 Isolation and characterisation of a novel Nesterenkonia species from a human bloodstream infection . International Journal of Antimicrobial Agents vol. 42 , s141 - s142 .
Hornsey M, Phee L, Woodford N, Turton J, Meunier D, Thomas C, Wareham DW ( 2013 ) . Evaluation of three selective chromogenic media, CHROMagar ESBL, CHROMagar CTX-M and CHROMagar KPC, for the detection of Klebsiella pneumoniae producing OXA-48 carbapenemase . Journal of Clinical Pathology vol. 66 , ( 4 ) 348 - 350 .
Hornsey M, Phee L, Woodford N, Turton J, Meunier D, Thomas C, Wareham DW ( 2013 ) . Evaluation of three selective chromogenic media, CHROMagar ESBL, CHROMagar CTX-M and CHROMagar KPC, for the detection of Klebsiella pneumoniae producing OXA-48 carbapenemase . J Clin Pathol vol. 66 , ( 4 ) 348 - 350 .
Hornsey M, Phee L, Longshaw C, Wareham DW ( 2013 ) . In vivo efficacy of telavancin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection . International Journal of Antimicrobial Agents vol. 41 , ( 3 ) 285 - 287 .
Hornsey M, Phee L, Longshaw C, Wareham DW ( 2013 ) . In vivo efficacy of telavancin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection . Int J Antimicrob Agents vol. 41 , ( 3 ) 285 - 287 .
Hornsey M, Phee L, Stubbings W, Wareham DW ( 2013 ) . In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens . International Journal of Antimicrobial Agents
Wareham D, Phee L, Hornsey M ( 2013 ) . Isolation and characterisation of a novel <i>Nesterenkonia</i> species from a human bloodstreaminfection . INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . vol. 42 , S141 - S142 .
Baillie S, Ireland K, Warwick S, Wareham D, Wilks M ( 2013 ) . Matrix-assisted laser desorption/ionisation-time of flight mass spectrometry: rapid identification of bacteria isolated from patients with cystic fibrosis . Br J Biomed Sci vol. 70 , ( 4 ) 144 - 148 .
Hornsey M, Longshaw C, Phee L, Wareham DW ( 2012 ) . In vitro activity of telavancin in combination with colistin versus Gram-negative bacterial pathogens . Antimicrob Agents Chemother vol. 56 , ( 6 ) 3080 - 3085 .
Waite RD, Wareham DW, Gardiner S, Whiley RA ( 2012 ) . A Simple, Semiselective Medium for Anaerobic Isolation of Anginosus Group Streptococci from Patients with Chronic Lung Disease . Journal of Clinical Microbiology vol. 50 , ( 4 ) 1430 - 1432 .
Hidalgo L, Hopkins KL, Wareham DW, Gutierrez B, Gonzalez-Zorn B ( 2012 ) . Association of Extended-Spectrum β-Lactamase VEB-5 and 16S rRNA Methyltransferase ArmA in <i>Salmonella enterica</i> from the United Kingdom . ANTIMICROBIAL AGENTS AND CHEMOTHERAPY vol. 56 , ( 9 ) 4985 - 4987 .
Hornsey M, Phee L, Wareham DW ( 2011 ) . A novel variant, NDM-5, of the New Delhi metallo-β-lactamase in a multidrug-resistant Escherichia coli ST648 isolate recovered from a patient in the United Kingdom . Antimicrob Agents Chemother vol. 55 , ( 12 ) 5952 - 5954 .
Reddy S, Rangaiah J, Addiman S, Wareham D, Wilson P, Sefton A ( 2011 ) . Epidemiology, antibiotic resistance trends and the cost of enteric fever in East London, 2005-2010 . Travel Med Infect Dis vol. 9 , ( 4 ) 206 - 212 .
Hornsey M, Wareham DW ( 2011 ) . In vivo efficacy of glycopeptide-colistin combination therapies in a Galleria mellonella model of Acinetobacter baumannii infection . Antimicrob Agents Chemother vol. 55 , ( 7 ) 3534 - 3537 .
Hornsey M, Loman N, Wareham DW, Ellington MJ, Pallen MJ, Turton JF, Underwood A, Gaulton T et al. ( 2011 ) . Whole-genome comparison of two Acinetobacter baumannii isolates from a single patient, where resistance developed during tigecycline therapy . J Antimicrob Chemother vol. 66 , ( 7 ) 1499 - 1503 .
Denton M, Doherty C, Foweraker J, Govan J, Hall M, Isalska B, Jones A, Kenna D et al. ( 2011 ) . 117 Results of an on-line survey of cystic fibrosis microbiology practices in UK laboratories . Journal of Cystic Fibrosis vol. 10 ,
Wareham DW, Gordon NC, Hornsey M ( 2011 ) . In vitro activity of teicoplanin combined with colistin versus multidrug-resistant strains of Acinetobacter baumannii . J Antimicrob Chemother vol. 66 , ( 5 ) 1047 - 1051 .
Phee L, Gordon N, Hornsey M, Wareham D ( 2011 ) . De-escalation of antimicrobial therapy in Gram-negative sepsis: easier said than done? . Critical Care vol. 15 , ( Suppl 1 )
Wareham DW, Gordon NC ( 2011 ) . Modifications to CHROMagar Acinetobacter for improved selective growth of multi-drug resistant Acinetobacter baumannii . J Clin Pathol vol. 64 , ( 2 ) 164 - 167 .
Shah A, Wareham D ( 2011 ) . EVALUATION OF RAPID E TEST MIC TESTING USING CHROM AGAR ON LOWER RESPIRATORY TRACT SAMPLES; COLLECTED FROM ICU FROM PATIENTS WITH SUSPECTED VENTILATOR ASSOCIATED PNEUMONIACATEGORY: LESSON IN MICROBIOLOGY & INFECTION CONTROL . JOURNAL OF INFECTION vol. 63 , ( 6 ) E22 - E23 .
Soleimanian S, Gordon NC, Wareham DW ( 2011 ) . Polymicrobial necrotizing fasciitis involving enterobacteria producing CTX-M-15 extended-spectrum β-lactamases . J Med Microbiol vol. 60 , ( Pt 1 ) 135 - 137 .
Wareham DW, Gordon NC, Shimizu K ( 2011 ) . Two new variants of and creation of a repository for Stenotrophomonas maltophilia quinolone protection protein (Smqnr) genes . Int J Antimicrob Agents vol. 37 , ( 1 ) 89 - 90 .
Gordon NC, Png K, Wareham DW ( 2010 ) . Potent synergy and sustained bactericidal activity of a vancomycin-colistin combination versus multidrug-resistant strains of Acinetobacter baumannii . Antimicrob Agents Chemother vol. 54 , ( 12 ) 5316 - 5322 .
Wareham DW, Umoren I, Khanna P, Gordon NC ( 2010 ) . Allele-specific polymerase chain reaction (PCR) for rapid detection of the aac(6')-Ib-cr quinolone resistance gene . Int J Antimicrob Agents vol. 36 , ( 5 ) 476 - 477 .
Hornsey M, Ellington MJ, Doumith M, Thomas CP, Gordon NC, Wareham DW, Quinn J, Lolans K et al. ( 2010 ) . AdeABC-mediated efflux and tigecycline MICs for epidemic clones of Acinetobacter baumannii . J Antimicrob Chemother vol. 65 , ( 8 ) 1589 - 1593 .
Gordon NC, Wareham DW ( 2010 ) . Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia . Int J Antimicrob Agents vol. 36 , ( 2 ) 129 - 131 .
Hall TJ, Wren MW, Wareham DW, Jeanes A, Gant VA ( 2010 ) . Effect of the dried residues of two hand gels on the survival of meticillin-resistant staphylococcus aureus and acinetobacter calcoaceticus-baumannii . Journal of Infection Prevention vol. 11 , ( 3 ) 70 - 72 .
Wareham D, Bean D ( 2010 ) . Molecular typing of multi-drug resistant Acinetobacter baumannii from London hospitals . INT J INFECT DIS vol. 14 , E36 - E36 .
Gordon NC, Wareham DW ( 2010 ) . Multidrug-resistant Acinetobacter baumannii: mechanisms of virulence and resistance . Int J Antimicrob Agents vol. 35 , ( 3 ) 219 - 226 .
Gordon NC, Wareham DW ( 2010 ) . Novel variants of the Smqnr family of quinolone resistance genes in clinical isolates of Stenotrophomonas maltophilia . J Antimicrob Chemother vol. 65 , ( 3 ) 483 - 489 .
Jozsef S, Wareham DW, Ratkai C, Aduse-Opoku J, Urban E, Elisabeth N ( 2010 ) . Prevalence, nucleotide sequence and expression studies of two proteins of a 5.6 kb, Class III, Bacteroides plasmid frequently found in clinical isolates from European countries . PLASMID vol. 63 , ( 2 ) 86 - 97 .
Wareham D, Bean D ( 2010 ) . Nebulised colistin for nosocomial Acinetobacter baumannii respiratory tract infection . Cochrane Database of Systematic Reviews , Wiley
Millar M, Wareham D ( 2010 ) . Infections associated with implanted medical devices . Antibiotic and Chemotherapy: Expert Consult ,
Shah A, Gordon N, Pheel L, Wareham D ( 2009 ) . Comparison of microscopic, phenotypic and molecular techniques for the rapid identification and susceptibility testing of Staphylococci from positive blood culture bottles . Critical Care vol. 13 , ( Suppl 4 )
Amin AK, Wareham DW ( 2009 ) . Plasmid-mediated quinolone resistance genes in Enterobacteriaceae isolates associated with community and nosocomial urinary tract infection in East London, UK . Int J Antimicrob Agents vol. 34 , ( 5 ) 490 - 491 .
Gordon NC, Wareham DW ( 2009 ) . Failure of the MicroScan WalkAway system to detect heteroresistance to carbapenems in a patient with Enterobacter aerogenes bacteremia . J Clin Microbiol vol. 47 , ( 9 ) 3024 - 3025 .
Gordon NC, Wareham DW ( 2009 ) . Evaluation of CHROMagar Acinetobacter for detection of enteric carriage of multidrug-resistant Acinetobacter baumannii in samples from critically ill patients . J Clin Microbiol vol. 47 , ( 7 ) 2249 - 2251 .
Soleimanian S, Wareham DW ( 2009 ) . Pancreatitis, Diarrhea, and Glycopeptide Dependence . Infectious Diseases in Clinical Practice vol. 17 , ( 3 ) 206 - 207 .
Amin AK, O'Connor I, Lavin K, Wareham DW ( 2009 ) . Prevention of an outbreak of nosocomial bloodstream infection associated with a new vascular access device by retraining of staff . J HOSP INFECT vol. 72 , ( 1 ) 85 - 87 .
Wareham DW, Gordon NC, Casals JB, Bean DC ( 2009 ) . Reduced susceptibility of multidrug-resistant Acinetobacter baumannii to tigecycline in combination with 1-(1-naphthylmethyl)-piperazine is not a pH-dependent phenomenon . J ANTIMICROB CHEMOTH vol. 63 , ( 5 ) 1075 - 1076 .
Gordon NC, Wareham DW ( 2009 ) . A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline . J Antimicrob Chemother vol. 63 , ( 4 ) 775 - 780 .
Bean DC, Wareham DW ( 2009 ) . Paradoxical effect of 1-(1-naphthylmethyl)-piperazine on resistance to tetracyclines in multidrug-resistant Acinetobacter baumannii . J Antimicrob Chemother vol. 63 , ( 2 ) 349 - 352 .
Woodford N, Wareham DW, UK Antibacterial Antisense Study Group ( 2009 ) . Tackling antibiotic resistance: a dose of common antisense? . J Antimicrob Chemother vol. 63 , ( 2 ) 225 - 229 .
Wareham DW, Bean DC, Khanna P, Hennessy EM, Krahe D, Ely A, Millar M ( 2008 ) . Bloodstream infection due to Acinetobacter spp: epidemiology, risk factors and impact of multi-drug resistance . Eur J Clin Microbiol Infect Dis vol. 27 , ( 7 ) 607 - 612 .
Bean DC, Krahe D, Wareham DW ( 2008 ) . Antimicrobial resistance in community and nosocomial Escherichia coli urinary tract isolates, London 2005-2006 . Ann Clin Microbiol Antimicrob vol. 7 ,
Khanna P, Doffman S, Griffiths L, Wareham D, Agrawal SG, Das S ( 2008 ) . A case of febrile nelitropenia with a skin rash . J INFECTION vol. 56 , ( 4 ) 309 - 309 .
Edwards J, Patel G, Wareham DW ( 2007 ) . Low concentrations of commercial alcohol hand rubs facilitate growth of and secretion of extracellular proteins by multidrug-resistant strains of Acinetobacter baumannii . J Med Microbiol vol. 56 , ( Pt 12 ) 1595 - 1599 .
Wareham D, Bean D ( 2007 ) . Nebulised colistin for nosocomial Acinetobacter baumannii respiratory tract infection . Cochrane Database of Systematic Reviews ( 4 )
Khanna P, Wareham DW, Bean DC, Krahé D ( 2007 ) . Microbiological surveillance of gram-negative bactaeremia in the intensive care unit: a teaching hospital experience . Journal of Infection vol. 55 , ( 3 )
Wareham DW, Curtis MA ( 2007 ) . A genotypic and phenotypic comparison of type III secretion profiles of Pseudomonas aeruginosa cystic fibrosis and bacteremia isolates . Int J Med Microbiol vol. 297 , ( 4 ) 227 - 234 .
Wareham DW, Breuer J ( 2007 ) . Herpes zoster . BMJ vol. 334 , ( 7605 ) 1211 - 1215 .
Ravic N, Tucker AT, Wareham DW, Johnston A, Hinds CJ ( 2007 ) . A study of novel oxides of nitrogen generating solution to prevent microbial colonization and ventilator associated pneumonia (VAP) . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 63 , 781 - 781 .
Michael JS, Wareham DW, El-Karim A, Warwick S, Millar M, Das SS ( 2007 ) . Evaluation of 16SrDNA PCR and sequencing for the diagnosis of infective endocarditis . CLIN RES CARDIOL vol. 96 , ( 6 ) 411 - 412 .
Khanna P, Krahe D, Bean D, Wareham D ( 2007 ) . P2040 Activity of tigecycline versus carbapenem–resistant strains of Acinetobacter spp . International Journal of Antimicrobial Agents . vol. 29 ,
Michael JS, Das SS, Wareham DW ( 2007 ) . The Dangers of Dog Bites . Journal of Infection vol. 54 , ( 3 )
Wareham DW, Michael JS, Warwick S, Whitlock P, Wood A, Das SS ( 2007 ) . The dangers of dog bites . J Clin Pathol vol. 60 , ( 3 ) 328 - 329 .
Pumbwe L, Wareham DW, Aduse-Opoku J, Brazier JS, Wexler HM ( 2007 ) . Genetic analysis of mechanisms of multidrug resistance in a clinical isolate of Bacteroides fragilis . Clin Microbiol Infect vol. 13 , ( 2 ) 183 - 189 .
Cepeda JA, Millar M, Sheridan EA, Warwick S, Raftery M, Bean DC, Wareham DW ( 2006 ) . Listeriosis due to infection with a catalase-negative strain of Listeria monocytogenes . J Clin Microbiol vol. 44 , ( 5 ) 1917 - 1918 .
Wareham DW, Bean DC ( 2006 ) . In-vitro activity of polymyxin B in combination with imipenem, rifampicin and azithromycin versus multidrug resistant strains of Acinetobacter baumannii producing OXA-23 carbapenemases . Ann Clin Microbiol Antimicrob vol. 5 ,
Wareham DW, Abbas H, Karcher AM, Das SS ( 2006 ) . Treatment of prosthetic valve infective endocarditis due to multi-resistant Gram-positive bacteria with linezolid . J Infect vol. 52 , ( 4 ) 300 - 304 .
Wareham DW, Bean DC ( 2006 ) . In vitro activities of polymyxin B, imipenem, and rifampin against multidrug-resistant Acinetobacter baumannii . Antimicrob Agents Chemother vol. 50 , ( 2 )
Wareham D ( 2005 ) . Postherpetic neuralgia . Clin Evid ( 14 ) 1017 - 1025 .
Wareham DW, Wilks M, Ahmed D, Brazier JS, Millar M ( 2005 ) . Anaerobic sepsis due to multidrug-resistant Bacteroides fragilis: microbiological cure and clinical response with linezolid therapy . Clin Infect Dis vol. 40 , ( 7 ) e67 - e68 .
Wareham DW, Papakonstantinopoulou A, Curtis MA ( 2005 ) . The Pseudomonas aeruginosa PA14 type III secretion system is expressed but not essential to virulence in the Caenorhabditis elegans-P. aeruginosa pathogenicity model . FEMS Microbiol Lett vol. 242 , ( 2 ) 209 - 216 .
WAREHAM DW, Das S, Michael J ( 2005 ) . Advances in bacterial specific imaging . Brazilian Archives of Biology and Technology vol. 48 , 145 - 152 .
WAREHAM DW, Das SS, Abbas H, Karcher AM ( 2005 ) . Treatment of infective endocarditis due to multiresistant Gram-positive bacteria with linezolid . J Infect
Wareham D ( 2004 ) . Postherpetic neuralgia . Clin Evid ( 12 ) 1182 - 1193 .
Wareham D ( 2003 ) . Postherpetic neuralgia . Clin Evid ( 10 ) 942 - 952 .
Lancaster T, Wareham D, Yaphe J ( 2003 ) . Postherpetic neuralgia . Clinical evidence ( 9 ) 890 - 900 .
Lancaster T, Wareham DW, Yaphe J ( 2003 ) . Postherpetic neuralgia . AM FAM PHYSICIAN vol. 67 , ( 7 ) 1557 - 1558 .
Das SS, Britton KE, Solanki KK, Wareham DW ( 2003 ) . (99m)Tc-ciprofloxacin scintigraphy in rabbit model of prosthetic joint infection . J Nucl Med vol. 44 , ( 2 ) 317 - 319 .
Britton KE, Wareham DW, Das SS, Solanki KK, Amaral H, Bhatnagar A, Katamihardja AHS, Malamitsi J et al. ( 2002 ) . Imaging bacterial infection with (99m)Tc-ciprofloxacin (Infecton) . J Clin Pathol vol. 55 , ( 11 ) 817 - 823 .
Das SS, Hall AV, Wareham DW, Britton KE ( 2002 ) . Infection imaging with radiopharmaceuticals in the 21(st) century . BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY . vol. 45 , 25 - 37 .
Das SS, Wareham DW, Britton KE ( 2002 ) . 99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections . J Nucl Med vol. 43 , ( 8 )
Lancaster T, Wareham D, Yaphe J ( 2002 ) . Postherpetic neuralgia . Clinical evidence ( 7 ) 738 - 746 .
Wareham DW, Wilson P ( 2002 ) . Chloramphenicol in the 21st century . Hosp Med vol. 63 , ( 3 ) 157 - 161 .
BRITTON KE, Soroa VE, Das SS, Sundram FX, Padhy AK, Wareham DW, Solanki KK, Moustafa HM et al. ( 2002 ) . Imaging bacterial infection with (99m)Tc-Ciprofloxacin (Infecton) . J Clin Pathol. vol. 55 , 817 - 823 .
BRITTON KE, Wareham DW, Hall AV, Das SS ( 2002 ) . Infection imaging with Radiopharmaceuticals in the Twenty-first century . Brazil Arch biol Tech. . vol. 45 , 25 - 37 .
Wareham DW, Döring G, Vochem M ( 2001 ) . Sepsis in a newborn due to Pseudomas aeruginosa from a contaminated tub bath [4] (multiple letters) . New England Journal of Medicine vol. 345 , ( 22 ) 1644 - 1645 .
Wareham DW ( 2001 ) . Sepsis in a newborn due to Pseudomonas aeruginosa from a contaminated tub bath . N Engl J Med vol. 345 , ( 22 ) 1644 - 1645 .
Britton KE, Wareham DW, Das SS ( 2001 ) . Concerns about 99mTc-labelled ciprofloxacin for infection detection . Eur J Nucl Med vol. 28 , ( 6 ) 779 - 781 .
Wareham DW, Breuer J, Healy MT, Goldhill DR ( 2001 ) . Pneumonitis in an elderly Bangladeshi man . J Clin Pathol vol. 54 , ( 6 )
BRITTON KE, Das SS, Wareham DW ( 2001 ) . Concerns about 99mTc-labelledCiprofloxacin for infection detection . Eur J Nucl Med. vol. 28 , 779 - 781 .
Breuer J, WAREHAM DW ( 2001 ) . Primary varicella infection presenting in old age . Grand Rounds vol. 1 , 3 - 4 .
Britton KE, Wareham D, Solanki KK, Das SS ( 2000 ) . Imaging of bacterial infections with Tc-99m-labeled human neutrophil peptide-1 . J NUCL MED vol. 41 , ( 12 ) 2099 - 2100 .
Wareham DW, Breuer J ( 2000 ) . Management of occupational exposure to hepatitis C: survey of United Kingdom practice . Communicable Disease and Public Health vol. 3 , ( 4 ) 295 - 296 .
Das SS, Britton KE, Solanki KK, Wareham DW ( 2000 ) . Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations . European Journal of Nuclear Medicine and Molecular Imaging vol. 27 , ( 12 ) 1865 - 1866 .
Britton KE, Solanki KK, Das SS, Amaral H, Bhatnagar A, Katamihardja AH, Malamitsi J, Moustafa H et al. ( 2000 ) . Bacterial specific imaging . JOURNAL OF NUCLEAR MEDICINE vol. 41 , ( 5 ) 11P - 11P .