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Publications:  Prof Christoph Thiemermann

Collotta D, Hull W, Mastrocola R, Chiazza F, Cento AS, Murphy C, Verta R, Alves GF et al.(2020). Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice. Molecular Metabolism vol. 39,
10.1016/j.molmet.2020.101009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64478
Purvis GSD, Collino M, Aranda-Tavio H, Chiazza F, O'Riordan CE, Zeboudj L, Mohammad S, Collotta D et al.(2020). Inhibition of Bruton's tyrosine kinase regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation. Br J Pharmacol
10.1111/bph.15182
Bangash MN, Abbott TEF, Patel NSA, Hinds C, Thiemermann C, Pearse R(2020). The Effect of β2-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia. Frontiers in Immunology vol. 11,
10.3389/fimmu.2020.01001
Zechendorf E, O'Riordan CE, Stiehler L, Wischmeyer N, Chiazza F, Collotta D, Denecke B, Ernst S et al.(2020). Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis. JCI Insight vol. 5, (8)
10.1172/jci.insight.131571
Lopez Tremoleda J, Wall J, Naganathar V, Praditsuktavorn B, Bugg O, Mcarthur S, Thiemermann C, Brohi K(2019). Modelling cardiac dysfunction following traumatic haemorrhage injury: impact on myocardial integrity. Frontiers in Immunology vol. 10,
10.3389/fimmu.2019.02774
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63503
O'Riordan CE, Purvis GSD, Collotta D, Chiazza F, Wissuwa B, Al Zoubi S, Stiehler L, Martin L et al.(2019). Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice. Frontiers in Immunology vol. 10,
10.3389/fimmu.2019.02129
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62208
Randall DW, Kieswich J, Swann J, McCafferty K, Thiemermann C, Curtis M, Hoyles L, Yaqoob MM(2019). Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: A cautionary tale. Microbiome vol. 7, (1)
10.1186/s40168-019-0738-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63836
Martin L, Derwall M, Al Zoubi S, Zechendorf E, Reuter DA, Thiemermann C, Schuerholz T(2019). Response. Chest vol. 156, (3) 636-637.
10.1016/j.chest.2019.05.013
Purvis GS, O'Riordan C, Aranda H, Bunyard P, Greaves DR, Thiemermann C (2019). Ibrutinib has anti-inflammatory and anti-diabetic effects in a model of HFD-induced insulin resistance and diabetic nephropathy. BRITISH JOURNAL OF PHARMACOLOGY. vol. 176, 2997-2997.
Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J et al.(2019). Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock. Ann Surg
10.1097/SLA.0000000000003407
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59582
Stiehler L, Riordan CO, Zechendorf E, Coldewey S, Wissuwa B, Dohmen F, Hinkelmann D, Ostareck-Lederer A et al. (2019). THE ROLE OF RIBONUCLEASE A AS POTENTIAL NEW THERAPEUTIC IN SEPTIC CARDIOMYOPATHY. SHOCK. vol. 51, 83-84.
SOLITO EGLE, PURVIS G, THIEMERMANN C(2019). Annexin-A1: therapeutic potential in microvascular disease. Frontiers in Immunology
10.3389/fimmu.2019.00938
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57697
VOISIN M, leoni G, WOODFIN A, loumagne L, PATEL N, Di Paola R, Cuzzocrea S, THIEMERMANN C et al.(2019). Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post ischemia/reperfusion injury. Journal of Pathology vol. 248, (1) 88-102.
10.1002/path.5234
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54857
Martin L, Derwall M, Al Zoubi S, Zechendorf E, Reuter DA, Thiemermann C, Schuerholz T(2019). Response. Chest vol. 155, (3) 647-648.
10.1016/j.chest.2018.10.018
Martin L, Derwall M, Al Zoubi S, Zechendorf E, Reuter DA, Thiemermann C, Schuerholz T(2019). The Septic Heart: Current Understanding of Molecular Mechanisms and Clinical Implications. Chest vol. 155, (2) 427-437.
10.1016/j.chest.2018.08.1037
Purvis GSD, Collino M, Loiola RA, Baragetti A, Chiazza F, Brovelli M, Sheikh MH, Collotta D et al.(2019). Identification of Annexina1 as an endogenous regulator of RhoA, and its role in the pathophysiology and experimental therapy of type-2 diabetes. Frontiers in Immunology vol. 10, (MAR)
10.3389/fimmu.2019.00571
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58923
Zingarelli B, Coopersmith CM, Drechsler S, Efron P, Marshall JC, Moldawer L, Wiersinga WJ, Xiao X et al.(2019). Part I: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Study Design and Humane Modeling Endpoints. Shock vol. 51, (1) 10-22.
10.1097/SHK.0000000000001243
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55169
Barry SP, Ounzain S, McCormick J, Scarabelli TM, Chen-Scarabelli C, Saravolatz LII, Faggian G, Mazzucco A et al.(2019). Retraction notice to "Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury" [Int. J. Cardiol. 163 (2013) 326-334]. Int J Cardiol vol. 274,
10.1016/j.ijcard.2018.10.031
Andrikopoulos P, Kieswich J, Pacheco S, Nadarajah L, Harwood SM, O¿Riordan CE, Thiemermann C, Yaqoob MM(2019). The MEK inhibitor trametinib ameliorates kidney fibrosis by suppressing ERK1/2 and mTORC1 signaling. Journal of the American Society of Nephrology vol. 30, (1) 33-49.
10.1681/ASN.2018020209
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54661
Osuchowski MF, Hellman J, Huber-Lang M, Libert C, Remick DG, Thiemermann C, Zingarelli B(2019). The Response to the Letter to the Editor Titled: "Is Triple Self-plagiarism "OK" If Only Made Transparent?" by Volker R Jacobs, MD, MBA. Shock vol. 51, (1) 140-141.
10.1097/SHK.0000000000001294
Kieswich JE, Chen J, Alliouachene S, Caton PW, McCafferty K, Thiemermann C, Yaqoob MM(2018). A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain 11 Medical and Health Sciences 1103 Clinical Sciences 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology. BMC Nephrology vol. 19, (1)
10.1186/s12882-018-1155-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60832
Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM et al.(2018). Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis (Infection, (2018), 46, 5, (687-691), 10.1007/s15010-018-1183-8). Infection vol. 46, (5) 745-747.
10.1007/s15010-018-1197-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55168
Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM et al.(2018). Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis. Infection vol. 46, (5) 687-691.
10.1007/s15010-018-1183-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55167
Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM et al.(2018). Minimum quality threshold in pre-clinical sepsis studies (mqtipss): An international expert consensus initiative for improvement of animal modeling in sepsis. Shock vol. 50, (4) 377-380.
10.1097/SHK.0000000000001212
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62544
Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon J-M, Chaudry IH, Coopersmith CM et al.(2018). Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis. Intensive Care Medicine Experimental vol. 6, (1) 26-26.
10.1186/s40635-018-0189-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63062
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al.(2018). Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis. FASEB Jfj201701303R-fj201701303R.
10.1096/fj.201701303R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50363
Khan AI, Kapoor A, Chen J, Martin L, Rogazzo M, Mercier T, Decosterd L, Collino M et al.(2018). The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction. Shock vol. 49, (6) 675-681.
10.1097/SHK.0000000000000963
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25644
Khan AI, Kapoor A, Chen J, Martin L, Rogazzo M, Mercier T, Decosterd L, Collino M et al.(2018). The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction. Shock vol. 49, (6) 675-681.
10.1097/SHK.0000000000000963
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43663
Aswani A, Manson J, Itagaki K, Chiazza F, Collino M, Wupeng WL, Chan TK, Wong WSF et al.(2018). Scavenging circulating mitochondrial DNA as a potential therapeutic option for multiple organ dysfunction in trauma hemorrhage. Frontiers in Immunology vol. 9, (MAY)
10.3389/fimmu.2018.00891
https://qmro.qmul.ac.uk/xmlui/handle/123456789/37104
Busch D, Kapoor A, Rademann P, Hildebrand F, Bahrami S, Thiemermann C, Osuchowski MF(2018). Delayed activation of PPAR-β/δ improves long-term survival in mouse sepsis: effects on organ inflammation and coagulation. Innate Immun vol. 24, (4) 262-273.
10.1177/1753425918771748
Zechendorf E, Vaßen P, Zhang J, Hallawa A, Martincuks A, Krenkel O, Müller-Newen G, Schuerholz T et al.(2018). Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning. Front Immunol vol. 9, 393-393.
10.3389/fimmu.2018.00393
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36371
Martin L, Thiemermann C(2018). Mitochondrial DNA in Acute Kidney Injury: Chicken or Egg?. Shock vol. 49, (3) 352-353.
10.1097/SHK.0000000000000966
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25886
Al Zoubi S, Chen J, Murphy C, Martin L, Chiazza F, Collotta D, Yaqoob MM, Collino M et al.(2018). Linagliptin Attenuates the Cardiac Dysfunction Associated With Experimental Sepsis in Mice With Pre-existing Type 2 Diabetes by Inhibiting NF-κB. Frontiers in immunology vol. 9,
10.3389/fimmu.2018.02996
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55015
Purvis GSD, Chiazza F, Chen J, Loiola RA, Martin L, Fountoulakis N, Gnudi L, Collino M et al.(2017). Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes. Diabetologia
10.1007/s00125-017-4469-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28601
Briegel J, Möhnle P, Vogeser M, Thiemermann C, Radermacher P(2017). Relative Adrenal Insufficiency in Cardiogenic Shock: Is There a Need for Action?. Shock vol. 48, (4) 498-499.
10.1097/SHK.0000000000000870
Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NSA et al.(2017). Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. Ann Surg vol. 265, (2) 408-417.
10.1097/SLA.0000000000001664
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19199
Johnson FL, Patel NSA, Purvis GSD, Chiazza F, Chen J, Sordi R, Hache G, Merezhko VV et al.(2017). Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis. J Am Heart Assoc vol. 6, (7)
10.1161/JAHA.116.005092
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24783
Martin L, Derwall M, Thiemermann C, Schürholz T(2017). [Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy]. Anaesthesist vol. 66, (7) 479-490.
10.1007/s00101-017-0329-x
Martin L, Gombert A, Chen J, Liebens J, Verleger J, Kalder J, Marx G, Jacobs M et al.(2017). The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and Men. Front Immunol vol. 8, 681-681.
10.3389/fimmu.2017.00681
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25296
Yamada N, Martin L, Zechendorf E, Chiazza F, Varrone B, Collino M, Shepherd J, Heinbockel L et al. (2017). A NOVEL SYNTHETIC, HOST-DEFENCE PEPTIDE PROTECTS AGAINST ORGAN INJURY/DYSFUNCTION IN A RAT-MODEL OF SEVERE HEMORRHAGIC SHOCK. vol. 47, is. 6, pp. 116-117.
Martin L, Chen J, Zechendorf E, Chiazza F, Oggero S, Collino M, Marx G, Schuerholz T et al. (2017). ROLE OF THE beta-D-ENDOGLUCURONIDASE HEPARANASE IN SEPTIC CARDIOMYOPATHY. SHOCK. Conference: European Shock Society vol. 47, 129-129.
Tremoleda JL, Watts SA, Reynolds PS, Thiemermann C, Brohi K(2017). Modelling Acute Traumatic Haemorrhagic Shock Injury: Challenges and Guidelines for Preclinical Studies. Shock
10.1097/SHK.0000000000000901
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23172
Osuchowski MF, Thiemermann C, Remick DG(2017). Sepsis-3 on the Block: What Does It Mean for Preclinical Sepsis Modeling?. Shock vol. 47, (5) 658-660.
10.1097/SHK.0000000000000775
Purvis GSD, Chiazza F, Collino M, Solito E, Thiemermann C (2017). Endogenous Annexin-A1 is a Protective Determinant in HFD-induced Insulin Resistance and Diabetic Nephropathy. FASEB JOURNAL. Conference: FASEB vol. 31,
Kalbitz M, Waller C, Huber-Lang M, Gebhard F, Thiemermann C, Radermacher P(2017). Oxygen in the Heart: How Much is too Much?. Shock vol. 47, (4) 531-532.
10.1097/SHK.0000000000000760
Yamada N, Lukas M, Zechendorf E, Purvis G, Chiazzo F, Varone B, Collino M, Shepherd J et al.(2017). Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock. Annals of Surgery
10.1097/SLA.0000000000002186
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23117
Purvis GSD, Chiazza F, Solito E, Collino M, Thiemermann C (2017). Endogenous annexin-A1 is a protective determinant in high-fat diet (HFD)-induced insulin resistance and diabetic nephropathy. DIABETIC MEDICINE. Conference: European Shock Society vol. 34, 26-26.
10.1111/dme.42_13304
Davenport RA, Guerreiro M, Frith D, Rourke C, Platton S, Cohen M, Pearse R, Thiemermann C et al.(2017). Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy. Anesthesiology vol. 126, (1) 115-127.
10.1097/ALN.0000000000001428
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17825
Chen J, Kieswich JE, Chiazza F, Moyes AJ, Gobbetti T, Purvis GSD, Salvatori DCF, Patel NSA et al.(2017). IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD. Journal of the American Society of Nephrology : JASN vol. 28, (1) 94-105.
10.1681/asn.2015060670
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12841
Martin L, Horst K, Chiazza F, Oggero S, Collino M, Brandenburg K, Hildebrand F, Marx G et al.(2016). The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis. Scientific Reports vol. 6,
10.1038/srep37277
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18186
Osuchowski MF, Thiemermann C, Remick DG(2016). SEPSIS-3 On the Block: What Does It Mean for Pre-Clinical Sepsis Modeling?. Shock
10.1097/SHK.0000000000000775
Yamada N, Martin L, Sordi R, Brandenburg K, Schuerholz T, Thiemermann C (2016). A NOVEL SYNTHETIC PEPTIDE PROTECTS AGAINST ORGAN INJURY IN A RAT-MODEL OF SEVERE HAEMORRHAGIC SHOCK. vol. 46, is. 4, pp. 34-35.
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A (2016). ACTIVATION OF TRPV1 BY 12(S)-HPETE AND 20-HETE RELEASES CGRP AND PROTECTS THE HEART AGAINST THE CARDIAC DYSFUNCTION CAUSED BY LPS. SHOCK. Conference: Exp Biology 2016 vol. 46, 31-32.
Martin LB, Zechendorf E, Chen J, Brandenburg K, Marx G, Thiemermann C, Schuerholz T (2016). THE SYNTHETIC ANTIMICROBIAL PEPTIDE 19-2.5 ATTENUATES SEPTIC CARDIOMYOPATHY IN A MURINE MODEL OF POLYMICROBIAL SEPSIS. SHOCK. Conference: Japanese Shock Society vol. 46, 31-31.
Asfar P, Thiemermann C, Radermacher P(2016). Norepinephrine, the Intensivist's Swiss Army Knife for Circulatory Shock?. Shock vol. 46, (1) 106-107.
10.1097/SHK.0000000000000590
Coldewey SM, Benetti E, Collino M, Pfeilschifter J, Sponholz C, Bauer M, Huwiler A, Thiemermann C(2016). Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis. Scientific Reports vol. 6, 27594-27594.
10.1038/srep27594
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13380
Chen J, Thiemermann C(2016). Selenium and niacin for sepsis therapy: The sum is greater than its parts. Critical Care Medicine vol. 44, (6) 1256-1257.
10.1097/CCM.0000000000001493
Sordi R, Chiazza F, Collino M, Assreuy J, Thiemermann C(2016). Neuronal Nitric Oxide Synthase is Involved in Vascular Hyporeactivity and Multiple Organ Dysfunction Associated with Hemorrhagic Shock. SHOCK vol. 45, (5) 525-533.
10.1097/SHK.0000000000000533
Gaffney VJ, Mota-Filipe H, Pinto RA, Thiemermann C, Loureiro M, Cardoso VV, Benoliel MJ, Almeida CM(2016). Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. Environmental toxicology and chemistry / SETAC
10.1002/etc.3451
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A (2016). Activation of TRPV1 by 12(s)-HpETE and 20-HETE Releases CGRP and Protects the Heart Against the Cardiac Dysfunction Caused by LPS. FASEB JOURNAL. Conference: Exp Biology (FASEB) 2016 vol. 30,
Chiazza F, Couturier-Maillard A, Benetti E, Mastrocola R, Nigro D, Cutrin JC, Serpe L, Aragno M et al.(2016). Targeting the NLRP3 Inflammasome to Reduce Diet-Induced Metabolic Abnormalities in Mice. Mol Med vol. 21, (1) 1025-1037.
10.2119/molmed.2015.00104
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14984
Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NSA et al.(2016). Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. Annals of surgery
Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NSA et al.(2016). Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. Ann Surg
10.1097/SLA.0000000000001664
Coldewey SM, Benetti E, Collino M, Bauer M, Huwiler A, Thiemermann C(2015). Enhanced sphingosine-1-phosphate levels ameliorate murine septic cardiomyopathy. Intensive Care Med Exp vol. 3, (Suppl 1)
10.1186/2197-425X-3-S1-A615
Madalli S, Beyrau M, Whiteford J, Duchene J, Nandhra IS, Patel NSA, Motwani MP, Gilroy DW et al.(2015). Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states. Biology of Sex Differences vol. 6, (1)
10.1186/s13293-015-0047-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12543
Coldewey SM, Benetti E, Collino M, Bauer M, Huwiler A, Thiemermann C (2015). ENHANCED SPHINGOSINE-1-PHOSPHATE LEVELS ATTENUATE CARDIAC DYSFUNCTION IN EXPERIMENTAL SEPTIC CARDIOMYOPATHY. SHOCK. vol. 44, 17-17.
Wall JM, Tremoleda JL, Thiemermann C, Brohi K (2015). HEART FATTY ACID BINDING PROTEIN (H-FABP) IS A BIOMARKER OF TRAUMA-INDUCED SECONDARY CARDIAC INJURY IN A PRE-CLINICAL MODEL OF TRAUMA-HAEMORRHAGE. SHOCK. vol. 44, 21-22.
Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NSA, Perretti M, Collino M, Yaqoob MM et al. (2015). THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE. SHOCK. vol. 44, 16-16.
Johnson F, Patel N, Collino M, Bennetti E, Thiemermann C (2015). THE LATE INHIBITION OF INHIBITOR OF IKB KINASE ATTENUATES ACUTE KIDNEY INJURY AND THE SUBSEQUENT DEVELOPMENT OF FIBROSIS IN A RAT MODEL OF ISCHAEMIA REPERFUSION INJURY. SHOCK. vol. 44, 10-10.
Sordi R, Nandra KK, Chiazza F, Patel NSA, Brohi K, Collino M, Thiemermann C (2015). TRAUMA ORGAN PROTECTION WITH ARTESUNATE (TOP-ART): PRECLINICAL EFFICACY OF AN ANTIMALARIAL DRUG WITH EXCELLENT SAFETY PROFILE AND PLANNED PHASE II RCT. SHOCK. vol. 44, 1-1.
Collino M, Thiemermann C, Cerami A, Brines M(2015). Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin. Pharmacol Ther vol. 151, 32-40.
10.1016/j.pharmthera.2015.02.005
Sordi R, Chiazza F, Johnson FL, Patel NSA, Brohi K, Collino M, Thiemermann C(2015). Inhibition of IκB kinase attenuates the organ injury and dysfunction associated with hemorrhagic shock. Molecular Medicine vol. 21, 563-575.
10.2119/molmed.2015.00049
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15622
Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NS, Perretti M, Collino M, Yaqoob MM et al. (2015). THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE. SHOCK. vol. 43, 92-93.
Sordi R, Chiazza F, Patel NSA, Doyle RA, Collino M, Thiemermann C(2015). 'Preconditioning' with low dose lipopolysaccharide aggravates the organ injury/dysfunction caused by hemorrhagic shock in rats. PLoS ONE vol. 10, (4)
10.1371/journal.pone.0122096
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12542
Lilley E, Armstrong R, Clark N, Gray P, Hawkins P, Mason K, López-Salesansky N, Stark A-K et al.(2015). Refinement of animal models of sepsis and septic shock. Shock vol. 43, (4) 304-316.
10.1097/SHK.0000000000000318
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6572
Hache G, Osuchowski M, Thiemermann C(2015). Does Insulin Protect the Brain in Mice and Man with Sepsis?. Shock vol. 44, (3)
10.1097/SHK.0000000000000423
Sand CA, Starr A, Wilder CDE, Rudyk O, Spina D, Thiemermann C, Treacher DF, Nandi M(2015). Quantification of microcirculatory blood flow: A sensitive and clinically relevant prognostic marker in murine models of sepsis. Journal of Applied Physiology vol. 118, (3) 344-354.
10.1152/japplphysiol.00793.2014
Gobbetti T, Coldewey SM, Chen J, McArthur S, Le Faouder P, Cenac N, Flower RJ, Thiemermann C et al.(2014). Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proceedings of the National Academy of Sciences of the United States of America vol. 111, (52) 18685-18690.
10.1073/pnas.1410938111
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6704
Collino M, Benetti E, Rogazzo M, Chiazza F, Mastrocola R, Nigro D, Cutrin JC, Aragno M et al.(2014). A non-erythropoietic peptide derivative of erythropoietin decreases susceptibility to diet-induced insulin resistance in mice. Br J Pharmacol vol. 171, (24) 5802-5815.
10.1111/bph.12888
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6706
Roesner JP, Thiemermann C(2014). Mirror, mirror on the wall, is off-pump better than on-pump at all?. Shock vol. 42, (2) 174-175.
10.1097/SHK.0000000000000202
Guerreiro M, Tremoleda JL, Frith D, Thiemermann C, Brohi K(2014). Reduction of the natural Activated protein C pathway activity significantly prevents coagulopathy in a murine model of acute traumatic coagulopathy. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine vol. 22, (1)
10.1186/1757-7241-22-S1-O6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6986
Osuchowski MF, Remick DG, Lederer JA, Lang CH, Aasen AO, Aibiki M, Azevedo LC, Bahrami S et al.(2014). Abandon the mouse research ship? Not just yet!. Shock vol. 41, (6) 463-475.
10.1097/SHK.0000000000000153
Osuchowski MF, Radermacher P, Thiemermann C(2014). Caught between a rock and a hard place: seeking an optimal resuscitation strategy for hemorrhaging patients with lung injury. Shock vol. 41, (6) 556-557.
10.1097/SHK.0000000000000159
Chen J, Chiazza F, Collino M, Coldewey SM, Patel NS, Thiemermann C (2014). GENDER DIMORPHISM OF THE CARDIAC DYSFUNCTION IN SEPSIS. SHOCK. vol. 41, 35-35.
Chen J, Kieswich J, Yaqoob MM, Thiemermann C (2014). PRE-EXISTING CHRONIC KIDNEY DISEASE WORSENS MYOCARDIAL DYSFUNCTION CAUSED BY SEPSIS IN MICE. SHOCK. vol. 41, 40-41.
Guerreiro ML, Tremoleda JL, Thiemermann C, Brohi K (2014). REDUCTION OF NATURAL ACTIVATED PROTEIN C PREVENTS COAGULOPATHY IN A PRECLINICAL ANIMAL MODEL OF ACUTE TRAUMATIC COAGULOPATHY. SHOCK. vol. 41, 51-51.
Radermacher P, Huber-Lang M, Knippschild U, Thiemermann C(2014). The obesity paradox revisited: does increased body mass protect against circulatory shock?. Shock vol. 41, (6) 554-555.
10.1097/SHK.0000000000000166
Coldewey SM, Thiemermann C(2014). PLEIOTROPIC EFFECTS OF ATORVASTATIN IN EXPERIMENTAL SEPSIS: PRESERVATION OF beta(1)-ADRENORECEPTOR SIGNALING IN THE HEART. SHOCK vol. 41, (5) 458-459.
10.1097/SHK.0000000000000154
Chapagain A, Caton PW, Kieswich J, Andrikopoulos P, Nayuni N, Long JH, Harwood SM, Webster SP et al.(2014). Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia. Proc Natl Acad Sci U S A vol. 111, (10) 3817-3822.
10.1073/pnas.1312436111
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12518
Jellestad L, Fink T, Pradarutti S, Kubulus D, Wolf B, Bauer I, Thiemermann C, Rensing H(2014). Inhibition of glycogen synthase kinase (GSK)-3-β improves liver microcirculation and hepatocellular function after hemorrhagic shock. Eur J Pharmacol vol. 724, 175-184.
10.1016/j.ejphar.2013.12.029
Chen J, Chiazza F, Collino M, Patel NSA, Coldewey SM, Thiemermann C(2014). Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency. PLoS One vol. 9, (6)
10.1371/journal.pone.0100631
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12540
Clemens MG, Radermacher P, Thiemermann C(2014). Nutritional support in critically ill patients: enteral, parenteral, or not at all?. Shock vol. 41, (1) 87-88.
10.1097/SHK.0000000000000076
McCafferty K, Forbes S, Thiemermann C, Yaqoob MM(2014). The challenge of translating ischemic conditioning from animal models to humans: The role of comorbidities. DMM Disease Models and Mechanisms vol. 7, (12) 1321-1333.
10.1242/dmm.016741
McCafferty K, Byrne CJ, Kieswich J, Raftery M, Thiemermann C, Yaqoob MM(2014). The effect of uraemia on the duration of arrhythmias in the context of cardioprotective ischaemic conditioning strategies. Heart Asia vol. 6, (1) 76-82.
10.1136/heartasia-2013-010432
Hafner S, Wepler M, McCook O, Scheuerle A, Wagner F, Matallo J, Chen J, Calzia E et al. (2013). EFFECTS OF THE PPAR-beta/delta AGONIST GW0742 ON RENAL INFLAMMATION AND KIDNEY TISSUE INJURY DURING RESUSCITATED PORCINE SEPTIC SHOCK. SHOCK. vol. 40, 24-24.
Coldewey SM, Khan AI, Kapoor A, Collino M, Rogazzo M, Brines M, Cerami A, Hall P et al.(2013). Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor. Kidney Int vol. 84, (3) 482-490.
10.1038/ki.2013.118
Rocha J, Barateiro A, Fernandes A, Raposo J, Direito R, Eduardo-Figueira M, Pinto R, Thiemermann C et al. (2013). GLYCOGEN SYNTHASE KINASE-3 INHIBITION REDUCES LIVER, NEUROMUSCULAR, AND LUNG INJURY CAUSED BY BURN INJURY IN THE RAT. SHOCK. vol. 40, 27-27.
Coldewey SM, Collino M, Rogazzo M, Patel NSA, Thiemermann C (2013). INHIBITION OF I kappa B KINASE-A NOVEL THERAPEUTIC APPROACH IN EXPERIMENTAL SEPSIS. SHOCK. vol. 40, 16-16.
Khan AI, Coldewey SM, Patel NSA, Rogazzo M, Collino M, Yagoob MM, Radermacher P, Kapoor A et al.(2013). Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the beta-common receptor. DISEASE MODELS & MECHANISMS vol. 6, (4) 1021-1030.
10.1242/dmm.011908
Coldewey SM, Rogazzo M, Collino M, Patel NSA, Thiemermann C(2013). Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse. Dis Model Mech vol. 6, (4) 1031-1042.
10.1242/dmm.012435
Radermacher P, van Griensven M, Thiemermann C(2013). Humane end points in experimental models of septic shock: a must, not a superfluous nightmare for researchers!. Shock vol. 39, (6) 541-542.
10.1097/SHK.0b013e3182941ac7
Radermacher P, Thiemermann C(2013). Receptor-selective vasopressin analogs: a new push for "decatecholaminization"?. Shock vol. 39, (6) 539-540.
10.1097/SHK.0b013e3182951982
Khan AI, Coldewey SM, Patel NS, Rogazzo M, Collino M, Yaqoob MM, Radermacher P, Kapoor A et al. (2013). ERYTHROPOIETIN ATTENUATES CARDIAC DYSFUNCTION IN EXPERIMENTAL SEPSIS VIA ACTIVATION OF THE B-COMMON RECEPTOR. HEART. vol. 99,
10.1136/heartjnl-2013-304019.233
Nandra KK, Collino M, Rogazzo M, Fantozzi R, Patel NSA, Thiemermann C(2013). Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock. Dis Model Mech vol. 6, (3) 701-709.
10.1242/dmm.011353
Radermacher P, Huber-Lang M, Thiemermann C(2013). Catecholamines and the septic heart: opening Pandora's box?. Shock vol. 39, (4) 404-405.
10.1097/SHK.0b013e31828b247b
Bangash MN, Patel NSA, Benetti E, Collino M, Hinds CJ, Thiemermann C, Pearse RM(2013). Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care vol. 17, (2)
10.1186/cc12585
https://qmro.qmul.ac.uk/xmlui/handle/123456789/4380
Shintani Y, Kapoor A, Kaneko M, Smolenski RT, D'Acquisto F, Coppen SR, Harada-Shoji N, Lee HJ et al.(2013). TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons. Proc Natl Acad Sci U S A vol. 110, (13) 5109-5114.
10.1073/pnas.1219243110
Barry SP, Ounzain S, McCormick J, Scarabelli TM, Chen-Scarabelli C, Saravolatz LII, Faggian G, Mazzucco A et al.(2013). Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury (Retracted article. See vol. 274, pg. 404, 2019). INTERNATIONAL JOURNAL OF CARDIOLOGY vol. 163, (3) 326-334.
10.1016/j.ijcard.2011.08.849
Collino M, Benetti E, Rogazzo M, Mastrocola R, Yaqoob MM, Aragno M, Thiemermann C, Fantozzi R(2013). Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR-delta agonism correlates with impaired NLRP3 inflammasome activation. BIOCHEMICAL PHARMACOLOGY vol. 85, (2) 257-264.
10.1016/j.bcp.2012.10.014
Calzia E, Huber-Lang M, Ignatius A, Radermacher P, Thiemermann C(2012). MODELING TRAUMATIC-HEMORRHAGIC SHOCK-NOTHING IS SIMPLE AND EASY. SHOCK vol. 38, (6) 685-686.
10.1097/SHK.0b013e3182756a24
McCafferty K, Byrne CJ, Kieswich J, Harwood S, Andrikopoulos P, Raftery M, Thiemermann C, Yaqoob MM(2012). Response to letter regarding article, "ischemic conditioning protects the uremic heart in a rodent model of myocardial infarction". Circulation vol. 126, (13)
10.1161/CIRCULATIONAHA.112.130971
Patel NSA, Nandra KK, Thiemermann C(2012). Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care. Crit Care vol. 16, (4)
10.1186/cc11315
https://qmro.qmul.ac.uk/xmlui/handle/123456789/2828
Nandra KK, Takahashi K, Collino M, Benetti E, Wong WSF, Goh FY, Suzuki K, Patel NSA et al.(2012). Acute treatment with bone marrow-derived mononuclear cells attenuates the organ injury/dysfunction induced by hemorrhagic shock in the rat. Shock vol. 37, (6) 592-598.
10.1097/SHK.0b013e31824e4c0d
Patel NSA, Kerr-Peterson HL, Brines M, Collino M, Rogazzo M, Fantozzi R, Wood EG, Johnson FL et al.(2012). Delayed administration of pyroglutamate helix B surface peptide (pHBSP), a novel nonerythropoietic analog of erythropoietin, attenuates acute kidney injury. Mol Med vol. 18, 719-727.
10.2119/molmed.2012.00093
Byrne CJ, McCafferty K, Kieswich J, Harwood S, Andrikopoulos P, Raftery M, Thiemermann C, Yaqoob MM(2012). Ischemic conditioning protects the uremic heart in a rodent model of myocardial infarction. Circulation vol. 125, (10) 1256-1265.
10.1161/CIRCULATIONAHA.111.055392
Khan AI, Coldewey SM, Kapoor A, Patel NS, Thiemermann C, Rogazzo M, Collino M (2012). ERYTHROPOIETIN ATTENUATES CARDIAC DYSFUNCTION IN EXPERIMENTAL SEPSIS VIA ACTIVATION OF THE BETA-COMMON RECEPTOR. SHOCK. vol. 37, 55-56.
10.1242/dmm.011908
Coldewey SM, Khan AI, Rogazzo M, Collino M, Kapoor A, Patel NS, Thiemermann C (2012). ERYTHROPOIETIN REDUCES THE ACUTE KIDNEY INJURY IN EXPERIMENTAL SEPSIS VIA ACTIVATION OF THE beta ETA-COMMON RECEPTOR. SHOCK. vol. 37, 52-52.
Frith D, Guerreiro M, Pearse R, Thiemermann C, Brohi K (2012). EXPERIMENTAL ACUTE TRAUMATIC COAGULOPATHY IS ASSOCIATED WITH MODERATE IMPAIRMENT OF THROMBIN GENERATION AND DYSFIBRINOGENEMIA. SHOCK. vol. 37, 34-34.
McCook O, Georgieff M, Scheuerle A, Moeller P, Thiemermann C, Radermacher P(2012). Erythropoietin in the critically ill: do we ask the right questions?. CRITICAL CARE vol. 16, (5) Article ARTN 319,
10.1186/cc11430
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12539
Duvigneau J, Patel NS, Kerr-Peterson H, Paier-Pourani J, Muellebner A, Weidinger A, Redl H, Thiemermann C et al. (2012). REMOTE EFFECTS OF KIDNEY ISCHEMIA/REPERFUSION INJURY ON THE LIVER INVOLVES ENDOPLASMIC RETICULUM STRESS. SHOCK. vol. 37, 119-119.
Nandra KK, Patel NS, Harwood S, Collino M, Rogazzo M, Yaqoob M, Thiemermann C (2012). THREE DAY PRE-TREATMENT WITH ERYTHROPOIETIN ATTENUATES THE ORGAN INJURY AND DYSFUNCTION INDUCED BY HEMORRHAGIC SHOCK IN THE RAT BY A MECHANISM INDEPENDENT OF ENDOTHELIAL PROGENITOR CELL MOBILISATION. SHOCK. vol. 37, 96-97.
Manson J, Thiemermann C, Brohi K(2012). Trauma alarmins as activators of damage-induced inflammation. Br J Surg vol. 99 Suppl 1, 12-20.
10.1002/bjs.7717
Shintani Y, Kapoor A, Drexler H, Terracciano C, Smolenski R, Kaneko M, Harada N, Coppen S et al.(2011). A Novel Toll-Like Receptor 9 Signaling in Cardiomyocytes. CIRCULATION vol. 124, (21)
Madalli S, Bauer M, Thiemermann C, Nourshargh S, Scotland R(2011). Differential Regulation of Neutrophil Mobilization and Integrin Expression in Females Protects Against Ischemia/Reperfusion-Induced Local and Remote Tissue Injury. CIRCULATION vol. 124, (21)
Patel NS, Collino M, Yaqoob MM, Thiemermann C(2011). Erythropoietin in the intensive care unit: beyond treatment of anemia. Ann Intensive Care vol. 1,
10.1186/2110-5820-1-40
https://qmro.qmul.ac.uk/xmlui/handle/123456789/4381
Patel NSA, Nandra KK, Brines M, Collino M, Wong WF, Kapoor A, Benetti E, Goh FY et al.(2011). A nonerythropoietic peptide that mimics the 3D structure of erythropoietin reduces organ injury/dysfunction and inflammation in experimental hemorrhagic shock. Mol Med vol. 17, (9-10) 883-892.
10.2119/molmed.2011.00053
Wang YY, Ryg U, Dahle MK, Steffensen KR, Thiemermann C, Chaudry IH, Reinholt FP, Collins JL et al.(2011). Liver X Receptor Protects against Liver Injury in Sepsis Caused by Rodent Cecal Ligation and Puncture. SURG INFECT vol. 12, (4) 283-289.
10.1089/sur.2010.066
Frith D, Baptista ML, Cohen M, Pearse R, Thiemermann C, Brohi K(2011). Experimental acute traumatic coagulopathy is due to systemic activation of protein c during hypoperfusion. JOURNAL OF THROMBOSIS AND HAEMOSTASIS vol. 9, 481-481.
Manson J, Davenport R, Coates A, Rourke C, De'Ath HD, Raza I, Spoors C, Khan S et al. (2011). TRAUMATIC TISSUE DAMAGE: THE SEARCH FOR TRAUMA ALARMINS. INFLAMMATION RESEARCH. vol. 60, 160-160.
Maio R, Sepodes B, Patel NSA, Thiemermann C, Mota-Filipe H, Costa P(2011). Erythropoietin preserves the integrity and quality of organs for transplantation after cardiac death. Shock vol. 35, (2) 126-133.
10.1097/SHK.0b013e3181e83236
Kapoor A, Thiemermann C(2011). Niacin as a novel therapy for septic shock?. Crit Care Med vol. 39, (2) 410-411.
10.1097/CCM.0b013e318205c05e
Collino M, Benetti E, Miglio G, Castiglia S, Rosa AC, Aragno M, Thiemermann C, Fantozzi R(2011). Peroxisome proliferator-activated receptor beta/delta agonism protects the kidney against ischemia/reperfusion injury in diabetic rats. FREE RADICAL BIO MED vol. 50, (2) 345-353.
10.1016/j.freeradbiomed.2010.10.710
Kapoor A, Thiemermann C(2011). Targeting CCR2 A Novel Therapeutic Strategy for Septic Shock?. AM J RESP CRIT CARE vol. 183, (2) 150-151.
10.1164/rccm.201009-1403ED
Kapoor A, Shintani Y, Collino M, Osuchowski MF, Busch D, Patel NSA, Sepodes B, Castiglia S et al. (2011). BENEFICIAL ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-BETA/DELTA IN SEPTIC SHOCK. SHOCK. vol. 36, 20-20.
Nandra K, Takahashi K, Collino M, Benetti E, Wong WSF, Goh FY, Salem H, Suzuki K et al.(2011). BONE-MARROW DERIVED MONONUCLEAR CELLS PROTECT AGAINST MULTIPLE ORGAN FAILURE IN HEMORRHAGIC SHOCK THROUGH AN AKT DEPENDANT PATHWAY. SHOCK vol. 36, 26-26.
Busch D, Kapoor A, Khadem A, Redl H, Thiemermann C, Bahrami S, Osuchowski MF(2011). DELAYED ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)-BETA/DELTA IMPROVES LONG-TERM SURVIVAL IN THE MOUSE MODEL OF POLYMICROBIAL SEPSIS. SHOCK vol. 36, 10-10.
Frith D, Baptista ML, Cohen MJ, Pearse R, Thiemermann C, Brohi K(2011). EXPERIMENTAL ACUTE TRAUMATIC COAGULOPATHY: INITIATED BY HYPOPERFUSION, MODULATED BY THE PROTEIN C PATHWAY. SHOCK vol. 36, 16-17.
Maio R, Sepodes B, Thiemermann C, Mota-Filipe H(2011). OPPORTUNITIES TO ENHANCE ORGAN VIABILITY. SHOCK vol. 36, 3-3.
Kapoor A, Shintani Y, Collino M, Osuchowski MF, Busch D, Patel NSA, Sepodes B, Castiglia S et al.(2010). Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock. Am J Respir Crit Care Med vol. 182, (12) 1506-1515.
10.1164/rccm.201002-0240OC
Frith D, Stanworth S, Gaarder C, Maegele M, Goslings C, Johansson P, Allard S, Cohen M et al.(2010). Acute traumatic coagulopathy is dependent upon injury load and shock. BRITISH JOURNAL OF SURGERY vol. 97, 39-40.
Lovell MJ, Yasin M, Lee KL, Cheung KK, Shintani Y, Collino M, Sivarajah A, Leung K-Y et al.(2010). Bone marrow mononuclear cells reduce myocardial reperfusion injury by activating the PI3K/Akt survival pathway. Atherosclerosis vol. 213, (1) 67-76.
10.1016/j.atherosclerosis.2010.07.045
Galuppo M, Di Paola R, Mazzon E, Esposito E, Paterniti I, Kapoor A, Thiemermann C, Cuzzocrea S(2010). GW0742, a high affinity PPAR-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice. Int J Immunopathol Pharmacol vol. 23, (4) 1033-1046.
10.1177/039463201002300408
Frith D, Goslings JC, Gaarder C, Maegele M, Cohen MJ, Allard S, Johansson PI, Stanworth S et al.(2010). Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations. J Thromb Haemost vol. 8, (9) 1919-1925.
10.1111/j.1538-7836.2010.03945.x
Kapoor A, Collino M, Castiglia S, Fantozzi R, Thiemermann C(2010). Activation of peroxisome proliferator-activated receptor-beta/delta attenuates myocardial ischemia/reperfusion injury in the rat. Shock vol. 34, (2) 117-124.
10.1097/SHK.0b013e3181cd86d6
Barry SP, Lawrence KM, McCormick J, Soond SM, Hubank M, Eaton S, Sivarajah A, Scarabelli TM et al.(2010). New targets of urocortin-mediated cardioprotection. J Mol Endocrinol vol. 45, (2) 69-85.
10.1677/JME-09-0148
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14936
Collino M, Aragno M, Castiglia S, Miglio G, Tomasinelli C, Boccuzzi G, Thiemermann C, Fantozzi R(2010). Pioglitazone improves lipid and insulin levels in overweight rats on a high cholesterol and fructose diet by decreasing hepatic inflammation. BRIT J PHARMACOL vol. 160, (8) 1892-1902.
10.1111/j.1476-5381.2010.00671.x
Ghezzi P, Bernaudin M, Bianchi R, Blomgren K, Brines M, Campana W, Cavaletti G, Cerami A et al.(2010). Erythropoietin: not just about erythropoiesis. Lancet vol. 375, (9732)
10.1016/S0140-6736(10)60992-0
Rehberg S, Thiemermann C, Traber DL(2010). Increased inotropism following PARP inhibition in the setting of myocardial reperfusion injury: another piece in the jigsaw?. Shock vol. 33, (6) 668-669.
10.1097/SHK.0b013e3181c24e87
Paterniti I, Esposito E, Mazzon E, Galuppo M, Di Paola R, Bramanti P, Kapoor A, Thiemermann C et al.(2010). Evidence for the Role of Peroxisome Proliferator-Activated Receptor-beta/delta in the Development of Spinal Cord Injury. J PHARMACOL EXP THER vol. 333, (2) 465-477.
10.1124/jpet.110.165605
Rehberg S, Thiemermann C, Maybauer MO(2010). Role of chelatable iron versus myoglobin in oxidative stress after crush trauma. Shock vol. 33, (5) 552-553.
10.1097/SHK.0b013e3181c24fa7
Esposito E, Paterniti I, Mazzon E, Genovese T, Galuppo M, Di Paola R, Bramanti P, Kapoor A et al.(2010). Evidence for the role of PPAR-beta/delta in the development of spinal cord injury. FASEB JOURNAL vol. 24,
Di Paola R, Crisafulli C, Mazzon E, Esposito E, Paterniti I, Galuppo M, Genovese T, Thiemermann C et al.(2010). GW0742, A HIGH-AFFINITY PPAR-beta/delta AGONIST, INHIBITS ACUTE LUNG INJURY IN MICE. SHOCK vol. 33, (4) 426-435.
10.1097/SHK.0b013e3181b8f2fb
Salem HK, Thiemermann C(2010). Mesenchymal stromal cells: current understanding and clinical status. Stem Cells vol. 28, (3) 585-596.
10.1002/stem.269
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12537
Galuppo M, Di Paola R, Mazzon E, Genovese T, Crisafulli C, Paterniti I, Cuzzocrea E, Bramanti P et al.(2010). Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study. J INFLAMM-LOND vol. 7, Article 12,
10.1186/1476-9255-7-12
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12538
Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ et al.(2010). Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice. NITRIC OXIDE-BIOL CH vol. 22, (2) 141-148.
10.1016/j.niox.2009.10.010
Kapoor A, Thiemermann C(2010). Hydrogen sulfide, neurogenic inflammation, and cardioprotection: A tale of rotten eggs and vanilloid receptors. CRIT CARE MED vol. 38, (2) 728-730.
10.1097/CCM.0b013e3181cab0ee
Frith D, Cohen M, Pearse R, Thiemermann C, Brohi K (2010). Rodent coagulation responses to trauma and haemorrhagic shock. INFLAMMATION RESEARCH. vol. 59, S26-S27.
Kumar S, Allen DA, Kieswich JE, Patel NSA, Harwood S, Mazzon E, Cuzzocrea S, Raftery MJ et al.(2009). Dexamethasone ameliorates renal ischemia-reperfusion injury. J Am Soc Nephrol vol. 20, (11) 2412-2425.
10.1681/ASN.2008080868
Wang YY, Dahle MK, Steffensen KR, Reinholt FP, Collins JL, Thiemermann C, Aasen AO, Gustafsson J-A et al.(2009). Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages. Shock vol. 32, (5) 548-553.
10.1097/SHK.0b013e3181a47f85
Scheiermann C, Colom B, Meda P, Patel NSA, Voisin M-B, Marrelli A, Woodfin A, Pitzalis C et al.(2009). Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler Thromb Vasc Biol vol. 29, (10) 1509-1515.
10.1161/ATVBAHA.109.187559
Maio R, Figueiredo N, Santos I, Thiemermann C, Mota-Filipe H, Costa P(2009). STRATEGIES TO IMPROVE THE QUALITY OF ORGANS FROM DCD. TRANSPL INT vol. 22, 43-43.
Milsom A, Patel N, Storey A, Cuzzocrea S, Mazzon E, Webb A, Hobbs A, Thiemermann C et al. (2009). Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischaemia-reperfusion injury in mice. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 20, S39-S40.
10.1016/j.niox.2009.10.010
Bianca RDD, Sorrentino R, Mitidieri E, Marzocco S, Autore G, Thiemermann C, Pinto A, Sorrentino R(2009). RECOMBINANT HUMAN ERYTHROPOIETIN PREVENTS LIPOPOLYSACCHARIDE-INDUCED VASCULAR HYPOREACTIVITY IN THE RAT. SHOCK vol. 31, (5) 529-534.
10.1097/SAK.0b013e31818909c0
di Villa Bianca RD, Sorrentino R, Mitidieri E, Marzocco S, Autore G, Thiemermann C, Pinto A, Sorrentino R(2009). Recombinant human erythropoietin prevents lipopolysaccharide-induced vascular hyporeactivity in the rat. Shock vol. 31, (5) 529-534.
10.1097/SHK.0b013e31818909c0
Ozuna H, Burke D, Wylie M, Ozuna-Vazquez H(2009). Alternative mRNA splicing of RAD5 on mouse tissues. FASEB JOURNAL vol. 23,
Genilo EJ, Dutta S, Keating A(2009). Determining specificities and affinities between BH3 peptides and BcL-2 proteins using yeast surface display. FASEB JOURNAL vol. 23,
Colom B, Scheiermann C, Woodfin A, Meda P, Patel N, Marrelli A, Pitzalis C, Thiemermann C et al.(2009). Effect of soluble JAM-C on leukocyte transmigration in models of ischemia/reperfusion injury. FASEB JOURNAL vol. 23,
Sepodes BM, Rocha JP, Eduardo-Figueira M, Thiemermann C, Mota-Filipe H(2009). Effects of Glycogen Synthase Kinase-beta Inhibition in Ischemia-Reperfusion Injury of the Liver. FASEB JOURNAL vol. 23,
Tripatara P, Patel NSA, Brancaleone V, Renshaw D, Rocha J, Sepodes B, Mota-Filipe H, Perretti M et al.(2009). Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. Eur J Pharmacol vol. 606, (1-3) 205-209.
10.1016/j.ejphar.2009.01.041
Sivarajah A, Collino M, Yasin M, Benetti E, Gallicchio M, Mazzon E, Cuzzocrea S, Fantozzi R et al.(2009). Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R. Shock vol. 31, (3) 267-274.
10.1097/SHK.0b013e318180ff89
Patel NSA, di Paola R, Mazzon E, Britti D, Thiemermann C, Cuzzocrea S(2009). Peroxisome proliferator-activated receptor-alpha contributes to the resolution of inflammation after renal ischemia/reperfusion injury. J Pharmacol Exp Ther vol. 328, (2) 635-643.
10.1124/jpet.108.146191
Patel NSA, Brines M, Sepodes B, Brown PAJ, Stewart KN, Mota-Filipe H, Cerami A, Thiemermann C (2009). A TISSUE PROTECTIVE, BUT NON-HAEMATOPOIETIC, ANALOGUE OF ERYTHROPOIETIN FOR THE TREATMENT OF ACUTE KIDNEY INJURY. SHOCK. vol. 32, 5-5.
Kapoor A, Collino M, Castiglia S, Fantozzi R, Thiemermann C (2009). ACTIVATION OF PPAR-beta/delta ATTENUATES MYOCARDIAL ISCHEMIA/REPERFUSION INJURY IN THE RAT. SHOCK. vol. 32, 23-23.
Frith D, Chesebro B, Pittet JF, Cohen MJ, Thiemermann C, Pearse R, Brohi K (2009). ACUTE TRAUMATIC COAGULOPATHY IS DRIVEN BY SYSTEMIC HYPOPERFUSION INDEPENDENT OF HYPOTENSION AND HAEMORRHAGE VOLUME. SHOCK. vol. 32, 9-9.
Nandra KK, Patel NSA, Thiemermann C (2009). DAILY PRETREATMENT WITH ERYTHROPOIETIN ATTENUATES THE TISSUE INJURY CAUSED BY HAEMORRHAGIC SHOCK. SHOCK. vol. 32, 11-11.
Cuzzoerea S, Galuppo M, Di Paola R, Mazzon E, Genovese T, Crisafulli C, Paterniti I, Kapoor A et al. (2009). GW0742, A HIGH AFFINITY PPAR-beta/delta AGONIST REDUCES THE DEVELOPMENT OF ZYMOSAN-INDUCED MULTIPLE ORGAN FAILURE IN MICE. SHOCK. vol. 32, 13-13.
Collino M, Aragno M, Castiglia S, Tomasinelli C, Thiemermann C, Boccuzzi G, Fantozzi R(2009). Insulin Reduces Cerebral Ischemia/Reperfusion Injury in the Hippocampus of Diabetic Rats A Role for Glycogen Synthase Kinase-3 beta. DIABETES vol. 58, (1) 235-242.
10.2337/db08-0691
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Kapoor A, Shintani Y, Collino M, Bailey LK, Patel NSA, Sepodes B, Tripatara P, Castiglia S et al. (2009). PPAR-B/delta ACTIVATION ATTENUATES ORGAN INJURY/DYSFUNCTION AND INFLAMMATION CAUSED BY ENDOTOXIN. SHOCK. vol. 32, 7-7.
Maio R, Figueiredo N, Santos I, Sepodes B, Thiemermann C, Mota-Filipe H, Costa P (2009). PRE-TREATMENT OF THE DONOR WITH ERYTHROPOIETIN AND TREATMENT OF THE RECIPIENT WITH 5-AIQ IMPROVES THE QUALITY OF ORGANS FROM DONORS AFTER CARDIAC DEATH (DCD), IN EXPERIMENTAL KIDNEY TRANSPLANTATION. SHOCK. vol. 32, 5-5.
Marques P, Rocha J, Pinto R, Sepodes B, Thiemermann C, Mota-Filipe H (2009). THE EFFECT OF LIPOPOLYSACCHARIDE PRECONDITIONING IN AN EXPERIMENTAL MODEL OF BURN INJURY IN THE RAT. SHOCK. vol. 32, 6-6.
Marques P, Rocha J, Pinto R, Sepodes B, Thiemermann C, Mota-Filipe H (2009). THE EFFECT OF SIMVASTATTN PRE-TREATMENT IN AN EXPERIMENTAL MODEL OF BURN INJURY IN THE RAT. SHOCK. vol. 32, 19-19.
Davenport R, Coates A, Allard S, Pasi J, MacCallum P, Stanworth S, Thiemermann C, Pearse R et al. (2009). TRAUMA HAEMORRHAGE: EVOLVING ROLE OF ROTEM FOR PREDICTING TRANSFUSION REQUIREMENTS. SHOCK. vol. 32, 15-15.
Eltze T, Boer R, Wagner T, Weinbrenner S, McDonald MC, Thiemermann C, Burkle A, Klein T(2008). Imidazoquinolinone, Imidazopyridine, and Isoquinolindione Derivatives as Novel and Potent Inhibitors of the Poly(ADP-ribose) Polymerase (PARP): A Comparison with Standard PARP Inhibitors. MOL PHARMACOL vol. 74, (6) 1587-1598.
10.1124/mol.108.048751
Yasin M, Shintani Y, Collino M, Takahashi K, Salem H, Kapoor A, Rucklidge G, Suzuki K et al. (2008). Bone Marrow Mononuclear Cell Therapy upon Reperfusion Reduces Myocardial Infarct Size by Activating the PI3K/Akt Survival Pathway. CIRCULATION. vol. 118, S380-S380.
Dugo L, Collin M, Allen DA, Patel NSA, Bauer I, Mervaala EMA, Louhelainen M, Foster SJ et al.(2008). Inhibiting Glycogen Synthase Kinase 3β in Sepsis. Sepsis: New Insights, New Therapies, vol. 280,
Tripatara P, Patel NSA, Collino M, Gallicchio M, Kieswich J, Castiglia S, Benetti E, Stewart KN et al.(2008). Generation of endogenous hydrogen sulfide by cystathionine gamma-lyase limits renal ischemia/reperfusion injury and dysfunction. Lab Invest vol. 88, (10) 1038-1048.
10.1038/labinvest.2008.73
Collino M, Thiemermann C, Mastrocola R, Gallicchio M, Benetti E, Miglio G, Castiglia S, Danni O et al.(2008). Treatment with the glycogen synthase kinase-3 beta inhibitor, TDZD-8, affects transient cerebral ischemia/reperfusion injury in the rat hippocampus. SHOCK vol. 30, (3) 299-307.
10.1097/SHK.0b013e318164e762
Thiemermann C(2008). What's new in Shock, September 2008?. Shock vol. 30, (3) 227-230.
10.1097/SHK.0b013e318181002b
Brines M, Patel NSA, Villa P, Brines C, Mennini T, De Paola M, Erbayraktar Z, Erbayraktar S et al.(2008). Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin. P NATL ACAD SCI USA vol. 105, (31) 10925-10930.
10.1073/pnas.0805594105
Todorovic Z, Nesic Z, Stojanovic R, Basta-Jovanovic G, Radojevic-Skodric S, Velickovic R, Chatterjee PK, Thiemermann C et al.(2008). Acute protective effects of simvastatin in the rat model of renal ischemia-reperfusion injury: It is never too late for the pretreatment. J PHARMACOL SCI vol. 107, (4) 465-470.
10.1254/jphs.SC0070374
Maio R, Figueiredo N, Santos I, Sepodes B, Mota-Filipe H, Thiemermann C, Costa P (2008). Strategies to improve the quality of organs from DCD: Pre-treat the donor with erythropoietin and treat the recipient with 5-aminoisoquinolinone. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 8, 303-303.
Figueiredo N, Maio R, Santos I, Sepodes B, Thiemermann C, Mota-Filipe H, Costa P (2008). The effect of 5-aminoisoquinolinone during machine perfusion of kidneys recovered after cardiac death (Experimental study). AMERICAN JOURNAL OF TRANSPLANTATION. vol. 8, 498-498.
Myhre AE, Agren J, Dahle MK, Tamburstuen MV, Lyngstadaas SP, Collins AJL, Foster SJ, Thiemermann C et al.(2008). Liver X receptor is a key regulator of cytokine release in human monocytes. Shock vol. 29, (4) 468-474.
10.1097/shk.0b013e31815073cb
Thiemermann C(2008). What's new in Shock, April 2008?. Shock vol. 29, (4) 427-430.
10.1097/SHK.0b013e31816c14e9
Murch O, Abdelrahman M, Kapoor A, Thiemermann C(2008). Muramyl dipeptide enhances the response to endotoxin to cause multiple organ injury in the anesthetized rat. Shock vol. 29, (3) 388-394.
10.1097/shk.0b013e3181453e59
Thiemermann C(2008). What's new in shock, March 2008. Shock vol. 29, (3) 311-314.
10.1097/SHK.0b013e31816470a0
Murch O, Abdelrahman M, Collino M, Gallicchio M, Benetti E, Mazzon E, Fantozzi R, Cuzzocrea S et al.(2008). Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat. Crit Care Med vol. 36, (2) 550-559.
10.1097/01.CCM.0B013E3181620D2F
Collino M, Patel NSA, Thiemermann C(2008). PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury. Therapeutic Advances in Cardiovascular Disease vol. 2, (3) 179-197.
10.1177/1753944708090924
Wang JE, Wang YY, Dahle MK, Sandvik A, Steffensen KR, Thiemermann C, Chaudry IH, Gustafsson JA et al. (2008). Role of liver X receptor in experimental sepsis. SHOCK. vol. 29, 101-101.
Frith D, Chesebro B, Patel N, Thiemermann C, Brohi K, Cohen M, Pearse R (2008). Towards a mouse model for acute coagulopathy of trauma/shock. SHOCK. vol. 29, 6-6.
Cuzzocrea S, Malleo G, Genovese T, Mazzon E, Esposito E, Muià C, Abdelrahman M, Di Paola R et al.(2007). Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice*. Crit Care Med
10.1097/01.CCM.0000295303.62996.9F
Ruud TE, Gundersen Y, Wang JE, Foster SJ, Thiemermann C, Aasen AO(2007). Activation of cytokine synthesis by systemic infusions of lipopolysaccharide and peptidoglycan in a porcine model in vivo and in vitro. Surg Infect (Larchmt) vol. 8, (5) 495-503.
10.1089/sur.2006.083
Thiemermann C(2007). What's new in shock, October 2007?. SHOCK vol. 28, (4) 371-374.
10.1097/shk.0b13e3181814a54f8
Sexton A, McDonald M, Cayla C, Thiemermann C, Ahluwalia A(2007). 12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1. FASEB J vol. 21, (11) 2695-2703.
10.1096/fj.06-7828com
Bao Z, Lim SH, Liao WP, Lin YZ, Thiemermann C, Leung BP, Wong WSF(2007). Glycogen synthase kinase-3 beta inhibition attenuates asthma in mice. AM J RESP CRIT CARE vol. 176, (5) 431-438.
10.1164/rccm.200609-1292OC
Cuzzocrea S, Genovese T, Mazzon E, Esposito E, Muia C, Abdelrahman M, Di Paola R, Bramanti P et al.(2007). Glycogen synthase kinase-3 beta inhibition attenuates the development of bleomycin-induced lung injury. INT J IMMUNOPATH PH vol. 20, (3) 619-630.
10.1177/039463200702000320
Bao Z, Lim S, Lin Y, Leung BP, Thiemermann C, Wong WSF(2007). Anti-inflammatory effects of GSK-3B inhibitor TDZD-8 in a mouse model of asthma. INFLAMM RES vol. 56, S416-S416.
Dugo L, Abdelrahman M, Murch O, Mazzon E, Cuzzocrea S, Thiemermann C(2007). Glycogen synthase kinase-3beta inhibitors protect against the organ injury and dysfunction caused by hemorrhage and resuscitation. INFLAMM RES vol. 56, S387-S387.
Albuszies G, Vogt J, Wachter U, Thiemermann C, Leverve XM, Weber S, Georgieff M, Radermacher P et al.(2007). The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock. INTENS CARE MED vol. 33, (6) 1094-1101.
10.1007/s00134-007-0638-7
Thiemermann C(2007). What's new in Shock, June 2007. SHOCK vol. 27, (6) 593-596.
10.1097/shk.0b013e3180546b6b
Patel NSA, Cuzzocrea S, Collino M, Chaterjee PK, Mazzon E, Britti D, Yaqoob MM, Thiemermann C(2007). The role of cycloxygenase-2 in the rodent kidney following ischaemia/reperfusion injury in vivo. Eur J Pharmacol vol. 562, (1-2) 148-154.
10.1016/j.ejphar.2007.01.079
Hadley JS, Wang JE, Michaels LC, Dempsey CM, Foster SJ, Thiemermann C, Hinds CJ(2007). Alterations in inflammatory capacity and TLR expression on monocytes and neutrophils after cardiopulmonary bypass. Shock vol. 27, (5) 466-473.
10.1097/01.shk.0000245033.69977.c5
Maio RF, Figueiredo NL, Sepodes BN, Thiemermann C, Mota-Filipe H, Costa PM (2007). Donor pre-treatment with erythropoietin - A way to improve the quality of organs from donation after cardiac death (experimental study). AMERICAN JOURNAL OF TRANSPLANTATION. vol. 7, 251-251.
Cuzzocrea S, Mazzon E, Esposito E, Muia C, Abdelrahman M, Di Paola R, Crisafulli C, Bramanti P et al.(2007). Glycogen synthase kinase-3 beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut. INTENS CARE MED vol. 33, (5) 880-893.
10.1007/s00134-007-0595-1
Figueiredo NL, Maio RF, Sepodes BN, Thiemermann C, Mota-Filipe H, Costa PM (2007). The effect of donor pre-treatment with erythropoietin in machine perfusion parameters (Experimental study). AMERICAN JOURNAL OF TRANSPLANTATION. vol. 7, 508-508.
Thiemermann C(2007). What's new in Shock, May 2007?. SHOCK vol. 27, (5) 457-460.
10.1097/shk.0b013e31804854ca
Whittle BJ, Varga C, Berko A, Horvath K, Posa A, Molnar A, Thiemermann C (2007). Attenuation of indomethacin-induced rat intestinal lesions, TNF alpha-production and iNOS activity by Tdzd-8, an inhibitor of glycogen synthase kinase-3p. GASTROENTEROLOGY. vol. 132, A564-A564.
Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B, Quesniaux VFJ, Evans TW et al.(2007). Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. Am J Respir Crit Care Med vol. 175, (6) 595-603.
10.1164/rccm.200608-1103OC
Sivarajah A, Collino M, Yasin M, Cuzzocrea S, Thiemermann C(2007). Hydrogen sulfide in disease. INFLAMM RES vol. 56, S261-S261.
Thiemermann C(2007). Inhibitors of glycogen-synthase kinase 3beta. INFLAMM RES vol. 56, S260-S260.
Dugo L, Collin M, Thiemermann C(2007). Glycogen synthase kinase 3beta as a target for the therapy of shock and inflammation. Shock vol. 27, (2) 113-123.
10.1097/01.shk.0000238059.23837.68
Tripatara P, Patel NSA, Webb A, Rathod K, Lecomte FMJ, Mazzon E, Cuzzocrea S, Yaqoob MM et al.(2007). Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. J Am Soc Nephrol vol. 18, (2) 570-580.
10.1681/ASN.2006050450
Thiemermann C(2007). Beneficial effects of erythropoietin in preclinical models of shock and organ failure. Crit Care vol. 11, (3)
10.1186/cc5912
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12541
Cuzzocrea S, Di Paola R, Mazzon E, Crisafulli C, Genovese T, Muia C, Abdelrahman M, Esposito E et al.(2007). Glycogen synthase kinase 3 beta inhibition reduces the development of nonseptic shock induced by zymosan in mice. SHOCK vol. 27, (1) 97-107.
10.1097/01.shk.0000235084.56100.71
Cuzzocrea S, Mazzon E, Esposito E, Muia C, Abdelrahman M, Di Paola R, Crisafulli C, Bramanti P et al. (2007). Glycogen synthase kinase-30 inhibition attenuates the development of ischemia/reperfusion injury of the gut. PROCEEDINGS OF THE 7TH WORLD CONGRESS ON TRAUMA, SHOCK, INFLAMMATION AND SEPSIS. 51-+.
Dugo L, Collin M, Allen DA, Patel NSA, Bauer I, Mervaala E, Louhelainen M, Foster SJ et al.(2007). Inhibiting glycogen synthase kinase 3beta in sepsis. Novartis Found Symp vol. 280, 128-142.
Murch O, Collin M, Hinds CJ, Thiemermann C(2007). Lipoproteins in inflammation and sepsis. I. Basic science. Intensive Care Med vol. 33, (1) 13-24.
10.1007/s00134-006-0432-y
Murch O, Collin M, Thiemermann C(2007). Lysophosphatidic acid reduces the organ injury caused by endotoxemia-a role for G-protein-coupled receptors and peroxisome proliferator-activated receptor-gamma. Shock vol. 27, (1) 48-54.
10.1097/01.shk.0000235086.63723.7e
Nesic Z, Todorovic Z, Stojanovic R, Basta-Jovanovic G, Radojevic-Skodric S, Velickovic R, Chatterjee PK, Thiemermann C et al.(2006). Single-dose intravenous simvastatin treatment attenuates renal injury in an experimental model of ischemia-reperfusion in the rat. J PHARMACOL SCI vol. 102, (4) 413-417.
10.1254/jphs.SCE06002X
Collino M, Aragno M, Mastrocola R, Benetti E, Gallicchio M, Dianzani C, Danni O, Thiemermann C et al.(2006). Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: Effects of the PPAR-alpha agonist WY14643 (vol 41, pg 579, 2006). FREE RADICAL BIO MED vol. 41, (10) 1619-1619.
10.1016/j.freeradbiomed.2006.09.013
Cuzzocrea S, Crisafulli C, Mazzon E, Esposito E, Muia C, Abdelrahman M, Di Paola R, Thiemermann C(2006). Inhibition of glycogen synthase kinase-3 beta attenuates the development of carrageenan-induced lung injury in mice. BRIT J PHARMACOL vol. 149, (6) 687-702.
10.1038/sj.bjp.0706902
Sepodes B, Maio R, Pinto R, Sharples E, Oliveira P, McDonald M, Yaqoob M, Thiemermann C et al.(2006). Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat. TRANSPLANT INT vol. 19, (11) 919-926.
10.1111/j.1432-2277.2006.00366.x
Sepodes B, Abdelrahman M, Rocha J, Pinto R, Mota-Filipe H, Thiemermann C (2006). A glycogen synthase kinase-3 inhibitor (TDZD-8) attenuates the liver and neuromuscular injury caused by burn in the rat. SHOCK. vol. 26, 20-20.
10.1097/00024382-200610001-00064
McCormick J, Barry SP, Sivarajah A, Stefanutti G, Townsend PA, Lawrence KM, Eaton S, Knight RA et al.(2006). Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury. FASEB J vol. 20, (12) 2115-+.
10.1096/fj.06-6188fje
Cuzzocrea S, Di Paola R, Mazzon E, Crisafulli C, Genovese T, Muia C, Abdelrahman M, Esposito E et al. (2006). Glycogen synthase kinase-3 beta inhibition reduces the development of non-septic shock induced by zymosan in mice. SHOCK. vol. 26, 6-7.
10.1097/00024382-200610001-00019
Sepodes B, Rocha J, Abdelrahman M, Pinto R, Oliveira P, Thiemermann C, Mota-Filipe H (2006). Inhibition of endogenous hydrogen sulphide formation protects the liver from hepatic ischemia-reperfusion injury in the rat. SHOCK. vol. 26, 15-16.
10.1097/00024382-200610001-00049
Ruud TE, Gundersen Y, Wang JE, Foster SJ, Thiemermann C, Aasen AO (2006). Systemic petidoglycan (PegG) stimulates proinflammatory responses in synergy with lipopolysaccharide (LPS) in an in vivo and in vitro porcine model. SHOCK. vol. 26, 32-32.
10.1097/00024382-200610001-00099
Albuszies G, Vogt J, Radermacher P, Weber S, Wachter U, Georgieff M, Thiemermann C, Barth E (2006). The role of iNOS for hepatic glucose production in murine septic shock. SHOCK. vol. 26, 3-4.
10.1097/00024382-200610001-00010
Thiemermann C(2006). What's new in Shock, October 2006?. SHOCK vol. 26, (4) 319-321.
10.1097/0.1shk.0000235129.05235.14
Thiemermann C(2006). What's new in Shock, September 2006?. SHOCK vol. 26, (3) 223-225.
10.1097/01.shk.0000235136.12858.b7
Collino M, Aragno M, Mastrocola R, Benetti E, Gallicchio M, Dianzani C, Danni O, Thiemermann C et al.(2006). Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: Effects of the PPAR-alpha agonist WY14643. FREE RADICAL BIO MED vol. 41, (4) 579-589.
10.1016/j.freeradbiomed.2006.04.030
Sivarajah A, McDonald MC, Thiemermann C(2006). The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. Shock vol. 26, (2) 154-161.
10.1097/01.shk.0000225722.56681.64
Bao Z, Lim SH, Thiemermann C, Wong WSF(2006). Anti-inflammatory effects of glycogen synthase kinase-3 beta inhibitor in a mouse asthma model. ACTA PHARMACOL SIN vol. 27, 270-270.
Agren J, Thiemermann C, Foster SJ, Wang JE, Aasen AO(2006). Cytokine responses to CpG DNA in human leukocytes. SCAND J IMMUNOL vol. 64, (1) 61-68.
10.1111/j.1365-3083.2006.01779.x
Cuzzocrea S, Genovese T, Mazzon E, Crisafulli C, Di Paola R, Muia C, Collin M, Esposito E et al.(2006). Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma. J PHARMACOL EXP THER vol. 318, (1) 79-89.
10.1124/jpet.106.102863
Abdelrahman M, Dugo L, Murch O, Mazzon E, Cuzzocrea S, Thiemermann C(2006). Glycogen synthase kinase-3-beta inhibitors attenuate the organ injury/dysfunction caused by hemorrhagic shock. ACTA PHARMACOL SIN vol. 27, 161-161.
Sepodes B, Abdelrahman M, Pinto R, Figueira ME, Mota-Filipe H, Thiemermann C(2006). Glycogen synthase kinase-3b inhibitor, TDZD-8, attenuates the liver injury caused by ischemia-reperfusion in the rat. ACTA PHARMACOL SIN vol. 27, 278-278.
THIEMERMANN C, Muia C, Di Paola R, Cuzzocrea S, Collin M, Crisafulli C, Dugo L, Mazzon E et al.(2006). Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse. Clin. Immunol vol. 120, (1) 57-67.
10.1016/j.clim.2006.03.005
Murch O, Collin M, Sepodes B, Foster SJ, Mota-Filipe H, Thiemermann C(2006). Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of gram-negative and gram-positive shock. Br J Pharmacol vol. 148, (6) 769-777.
10.1038/sj.bjp.0706788
Thiemermann C(2006). Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of Ischemia-Reperfusion injury. ACTA PHARMACOL SIN vol. 27, 37-37.
Bar-Or D, McDonald MC, Thiemermann C(2006). Reduction of infarct size in a rat model of regional myocardial ischemia and reperfusion by the synthetic peptide DAHK. CRIT CARE MED vol. 34, (7) 1955-1959.
10.1097/01.CCM.0000220493.10289.03
Thiemermann C(2006). The spice of life: Curcumin reduces the mortality associated with experimental sepsis. CRIT CARE MED vol. 34, (7) 2009-2011.
10.1097/01.CCM.0000226836.72913.C4
Wang YY, Dahle MK, Collins JL, Thiemermann C, Aasen AO, Wang JE (2006). Activation of liver x receptor by synthetic agonist t0901317 reduces the liver injury caused by lipopolysaccharide in the rat: A novel principle for treatment of sepsis and shock. SHOCK. vol. 25, 72-72.
10.1097/00024382-200606001-00217
Myhre AE, Lyngstadaas SP, Dahle MK, Stuestol JF, Foster SJ, Thiemermann C, Lilleaasen P, Wang JE et al.(2006). Anti-inflammatory properties of enamel matrix derivative in human blood. J PERIODONTAL RES vol. 41, (3) 208-213.
10.1111/j.1600-0765.2005.00863.x
Patel NSA, Tripatara P, Thiemermann C (2006). Inhibition of hydrogen sulfide synthesis protects the rat kidney in vivo against ischemia-reperfusion injury. SHOCK. vol. 25, 37-37.
10.1097/00024382-200606001-00110
Murch O, Wray J, Collin M, Bishop-Bailey D, Thiemermann C (2006). Lysophosphatidic acid reduces the organ injury caused by endotoxemia via activation of G-protein-coupled receptors, but not peroxisome proliferator-activated receptor gamma. SHOCK. vol. 25, 72-72.
10.1097/00024382-200606001-00218
Lovell M, McDonald M, Sivarajah A, Harrington D, Ferguson S, Wright N, Thiemermann C, Mathur A (2006). Bone marrow mononuclear cells home to the heart in the acute setting of myocardial infarction with no adverse effects on cardiac function. HEART. vol. 92, A70-A71.
Dugo L, Abdelrahman M, Murch O, Mazzon E, Cuzzocrea S, Thiemermann C(2006). Glycogen synthase kinase-3beta inhibitors protect against the organ injury and dysfunction caused by hemorrhage and resuscitation. Shock vol. 25, (5) 485-491.
10.1097/01.shk.0000209545.29671.31
Dugo L, Collin M, Allen DA, Murch O, Foster SJ, Yaqoob MM, Thiemermann C(2006). Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: role of glycogen synthase kinase-3beta inhibition. Crit Care Med vol. 34, (5) 1489-1496.
10.1097/01.CCM.0000215457.83953.E3
Lovell M, McDonald M, Sivarajah A, Wright N, Thiemermann C, Mathur A (2006). Localisation of bone marrow mononuclear cells administered during acute myocardial infarction; The effects of time in culture. HEART. vol. 92, A69-A70.
Thiemermann C(2006). What's new in SHOCK, May 2006?. SHOCK vol. 25, (5) 429-431.
10.1097/01.shk.0000215323.29736.cl
Thiemermann C, Yaqoob MM(2006). Cardio-renal interface in translational and clinical research. CURR OPIN PHARMACOL vol. 6, (2) 121-124.
10.1016/j.coph.2006.02.001
Cuzzocrea S, Di Paola R, Mazzon E, Patel NSA, Genovese T, Muia C, Crisafulli C, Caputi AP et al.(2006). Erythropoietin reduces the development of nonseptic shock induced by zymosan in mice. CRIT CARE MED vol. 34, (4) 1168-1177.
10.1097/01.CCM.0000207346.56477.E8
Whittle BJ, Varga C, Berko A, Posa A, Molnar A, Collin M, Thiemermann C (2006). Modulation of rat colonic TNF-alpha, iNOS and acute colitis through down-regulation of NF-kappa B by glycogen synthase kinase-3 beta inhibition. GASTROENTEROLOGY. vol. 130, A551-A551.
Sharples EJ, Thiemermann C, Yaqoob MM(2006). Novel applications of recombinant erythropoietin. Curr Opin Pharmacol vol. 6, (2) 184-189.
10.1016/j.coph.2006.01.003
Collin M, Murch O, Thiemermann C(2006). Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia. CRIT CARE MED vol. 34, (4) 1131-1138.
10.1097/01.CCM.0000206472.63040.60
Collin M, Murch O, Thiemermann C(2006). Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia. Crit Care Med vol. 34, (4) 1131-1138.
10.1097/01.CCM.0000206472.63040.6D
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Wang YY, Dahle MK, Agren J, Myhre AE, Reinholt FP, Foster SJ, Collins JL, Thiemermann C et al.(2006). Activation of the liver X receptor protects against hepatic injury in endotoxemia by suppressing Kupffer cell activation. SHOCK vol. 25, (2) 141-146.
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Barth E, Radermacher P, Thiemermann C, Weber S, Georgieff M, Albuszies G(2006). Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock. CRIT CARE MED vol. 34, (2) 307-313.
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Collin M, Thiemermann C(2005). Hydrogen sulfide and sulfite: Novel mediators in the pathophysiology of shock and inflammation. SHOCK vol. 24, (6) 595-596.
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Sharples EJ, Thiemermann C, Yaqoob MM(2005). Mechanisms of disease: Cell death in acute renal failure and emerging evidence for a protective role of erythropoietin. Nat Clin Pract Nephrol vol. 1, (2) 87-97.
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Hadley JS, Wang JE, Foster SJ, Thiemermann C, Hinds CJ(2005). Peptidoglycan of Staphylococcus aureus upregulates monocyte expression of CD14, Toll-like receptor 2 (TLR2), and TLR4 in human blood: possible implications for priming of lipopolysaccharide signaling. Infect Immun vol. 73, (11) 7613-7619.
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Collin M, Anuar FBM, Murch O, Bhatia M, Moore PK, Thiemermann C(2005). Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia. Br J Pharmacol vol. 146, (4) 498-505.
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Dugo L, Collin M, Allen DA, Patel NSA, Bauer I, Mervaala EMA, Louhelainen M, Foster SJ et al.(2005). GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat. Crit Care Med vol. 33, (9) 1903-1912.
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Wang YY, Myhre AE, Pettersen SJ, Dahle MK, Foster SJ, Thiemermann C, Bjørnland K, Aasen AO et al.(2005). Peptidoglycan of Staphylococcus aureus induces enhanced levels of matrix metalloproteinase-9 in human blood originating from neutrophils. Shock vol. 24, (3) 214-218.
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Collino M, Patel NSA, Lawrence KM, Collin M, Latchman DS, Yaqoob MM, Thiemermann C(2005). The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion. Kidney Int vol. 68, (2) 529-536.
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Collin M, Murch O, Thiemermann C (2005). Lysophosphatidylcholine reduces the multiple organ injury and dysfunction caused by endotoxemia in the rat. SHOCK. vol. 23, 41-41.
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Patel NSA, Collino M, Collin M, Thiemermann C (2005). The selective PPAR gamma antagonist GW9662 abolished the protection afforded by lpspretreatment in a rat model of renal ischemia/reperfusion injury. SHOCK. vol. 23, 30-31.
Genovese T, Mazzon E, Di Paola R, Muia C, Threadgill MD, Caputi AP, Thiemermann C, Cuzzocrea S(2005). Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury. J PHARMACOL EXP THER vol. 313, (2) 529-538.
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Patel NSA, Chatterjee PK, Di Paola R, Mazzon E, Britti D, De Sarro A, Cuzzocrea S, Thiemermann C(2005). Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion. J Pharmacol Exp Ther vol. 312, (3) 1170-1178.
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Cuzzocrea S, Mazzon E, di Paola R, Genovese T, Patel NSA, Britti D, de Majo M, Caputi AP et al.(2005). Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse. Arthritis Rheum vol. 52, (3) 940-950.
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Patel NSA, Cortes U, Di Poala R, Mazzon E, Mota-Filipe H, Cuzzocrea S, Wang Z-Q, Thiemermann C(2005). Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury. J Am Soc Nephrol vol. 16, (3) 712-719.
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Abdelrahman M, Mazzon E, Bauer M, Bauer I, Delbosc S, Cristol J-P, Patel NSA, Cuzzocrea S et al.(2005). Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock. Shock vol. 23, (2) 107-114.
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Genovese T, Mazzon E, Muia C, Patel NSA, Threadgill MD, Bramanti P, De Sarro A, Thiemermann C et al.(2005). Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma. J PHARMACOL EXP THER vol. 312, (2) 449-457.
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Di Paola R, Mazzon E, Patel NSA, Genovese T, Muia C, Thiemermann C, De Sarro A, Cuzzocrea S(2005). Beneficial effects of GW274150 treatment on the development of experimental colitis induced by dinitrobenzene sulfonic acid. EUR J PHARMACOL vol. 507, (1-3) 281-289.
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Dugo L, Collin M, Cuzzocrea S, Thiemermann C (2005). 15d-PGJ(2) reduces the multiple organ failure caused by wall-fragments of Gram-positive and Gram-negative bacteria. SHOCK. vol. 23, 42-42.
Di Paola R, Genovese T, Caputi AP, Threadgill M, Thiemermann C, Cuzzocrea S (2005). Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of the of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion. SHOCK. vol. 23, 13-14.
Barth E, Radermacher P, Thiemermann C, Weber S, Georgieff M, Albuszies G (2005). Effetcs of selective iNOS inhibition with GW274150 on catecholamine reactivity during hyperdynamic murine septic shock. SHOCK. vol. 23, 57-57.
Abdelrahman M, Bauer M, Bauer I, Delbosc S, Cristol JP, Patel NSA, Cuzzocrea S, Thiemermann C (2005). Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock. SHOCK. vol. 23, 53-53.
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Genovese T, Mazzon E, Muia C, Patel NSA, Threadgill MD, Bramanti P, De Sarro A, Thiemermann C et al. (2005). Inhibitors of poly (ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma. SHOCK. vol. 23, 19-19.
Patel NSA, Cortes U, Di Poala R, Mazzon E, Filipe HM, Cuzzocrea S, Wang ZQ, Thiemermann C (2005). Mice lacking the 110 KDa isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia-reperfusion injury. SHOCK. vol. 23, 40-40.
Klouche K, Delbosc S, Abdelrahman M, Cristol JP, Thiemermann C (2005). Oxidative stress tissular production precedes organ dysfunction during animal septic shock. SHOCK. vol. 23, 51-51.
WHITTLE BJR, Thiemermann C, Collin M, Varga C, Posa A, Molnar A(2005). Reduction of Experimental Colitis in the Rat by Inhibitors of Glycogen Synthase Kinase-3b. J Pharmacol vol. 147, 575-582.
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Cuzzocrea S, Dugo L, Patel NSA, Di Paola R, Genovese T, Muia C, Caputi AP, Thiemermann C (2005). Rosiglitazont and 15-deoxy-Delta(12,14)-prostaglandin J(2), ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. SHOCK. vol. 23, 41-42.
Agren J, Foster SJ, Thiemermann C, Wang JE, Aasen AO (2005). Synthetic CpG- and GpC oligonucleotides enhance the TNF alpha release induced by peptidoglycan but not by lipopolysaccharide. SHOCK. vol. 23, 22-22.
Sivarajah A, McDonald MC, Thiemermann C (2005). The cardioprotective effects of preconditioning with endotoxin, but not ischemia, are abolished by a PPAR-gamma antagonist. SHOCK. vol. 23, 41-41.
Hadley JS, Wang JE, Michaels LC, Foster SJ, Thiemermann C, Hinds CJ (2005). The effect of cardiopulmonary bypass (CPB) on monocyte receptor expression and ex vivo cytokine production. SHOCK. vol. 23, 72-72.
Sepodes B, Pinto R, McDonald M, Eduardo-Figueira M, Thiemermann C, Mota-Filipe H (2005). Tyrphostin AG126 reduces ischemia-reperfusion injury of the liver in the rat. SHOCK. vol. 23, 39-39.
Cuzzocrea S, Mazzon E, Di Paola R, Genovese T, Patel NSA, Muia C, Threadgill MD, De Sarro A et al.(2004). 5-Aminoisoquinolinone reduces colon injury by experimental colitis. N-S ARCH PHARMACOL vol. 370, (6) 464-473.
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Cuzzocrea S, Mazzon E, Di Paola R, Patel NSA, Genovese T, Muia C, De Sarro A, Thiemermann C(2004). Erythropoietin reduces the development of experimental inflammatory bowel disease. J PHARMACOL EXP THER vol. 311, (3) 1272-1280.
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Hauser B, Radermacher P, Thiemermann C, Matejovic M(2004). Nitric oxide, bacteria, and host defense in sepsis: Who needs what?. SHOCK vol. 22, (6) 588-590.
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Abdelrahman M, Collin M, Thiemermann C(2004). The peroxisome proliferator-activated receptor-gamma ligand 15-deoxyDelta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock. Shock vol. 22, (6) 555-561.
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Collin M, Rossi A, Cuzzocrea S, Patel NSA, Di Paola R, Hadley J, Collino M, Sautebin L et al.(2004). Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton. J Leukoc Biol vol. 76, (5) 961-970.
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Chatterjee PK, Todorovic Z, Sivarajah A, Mota-Filipe H, Brown PAJ, Stewart KN, Cuzzocrea S, Thiemermann C(2004). Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney. Eur J Pharmacol vol. 503, (1-3) 173-183.
10.1016/j.ejphar.2004.09.025
Petrilli V, Herceg Z, Hassa PO, Patel NSA, Di Paola R, Cortes U, Dugo L, Filipe HM et al.(2004). Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammatbn response in mice. J CLIN INVEST vol. 114, (8) 1072-1081.
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Wang JE, Pettersen S, Stuestol JF, Wang YY, Foster SJ, Thiemermann C, Aasen AO, Bjorland K(2004). Peptidoglycan of S-aureus causes increased levels of matrix metalloproteinases in the rat. SHOCK vol. 22, (4) 376-379.
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Dugo L, Collin M, Cuzzocrea S, Thiemermann C(2004). 15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria. Eur J Pharmacol vol. 498, (1-3) 295-301.
10.1016/j.ejphar.2004.07.074
Patel NSA, Sharples EJ, Cuzzocrea S, Chatterjee PK, Britti D, Yaqoob MM, Thiemermann C(2004). Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo. Kidney Int vol. 66, (3) 983-989.
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Patel NSA, Collin M, Thiemermann C(2004). Urocortin does not reduce the renal injury and dysfunction caused by experimental ischaemia/reperfusion. Eur J Pharmacol vol. 496, (1-3) 175-180.
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Sharples EJ, Patel N, Brown P, Stewart K, Mota-Philipe H, Sheaff M, Kieswich J, Allen D et al.(2004). Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion. J Am Soc Nephrol vol. 15, (8) 2115-2124.
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Patel NSA, Cuzzocrea S, Chatterjee PK, Di Paola R, Sautebin L, Britti D, Thiemermann C(2004). Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton. Mol Pharmacol vol. 66, (2) 220-227.
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Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Patel NSA, Caputi AP, Thiemermann C(2004). Tempol reduces the activation of nuclear factor-kappa B in acute inflammation. FREE RADICAL RES vol. 38, (8) 813-819.
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Cuzzocrea S, Genovese T, Di Paola R, Mastruzzo C, Dugo L, Sortino M, Crimi N, Caputi AP et al.(2004). Effect of rosiglitazone and 15-deoxy-Delta 12,14-prostaglandin J2 on bleomycin-induced lung injury. FUNDAMENTAL & CLINICAL PHARMACOLOGY vol. 18, 90-90.
Abdelrahman M, Sharples EJ, McDonald MC, Collin M, Patel NSA, Yaqoob MM, Thiemermann C(2004). Erythropoietin attenuates the tissue injury associated with hemorrhagic shock and myocardial ischemia. Shock vol. 22, (1) 63-69.
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Thiemermann C(2004). Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size. CARDIOVASC RES vol. 63, (1) 8-10.
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Thiemermann C(2004). Ligands of the peroxisome proliferator-activated receptor-gamma and heart failure. Br J Pharmacol vol. 142, (6) 1049-1051.
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Cuzzocrea S, Mazzon E, Dugo L, Patel N, Di Paola R, Genovese T, Britti D, De Majo M et al.(2004). Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce the evolution of murine type II collagen-induced arthritis. FUNDAMENTAL & CLINICAL PHARMACOLOGY vol. 18, 90-90.
Sepodes B, Pinto R, McDonald M, Thiemermann C, Mota-Filipe H(2004). The effect of haemoglobin pretreatment on the liver ischaemia/reperfusion injury. FUNDAMENTAL & CLINICAL PHARMACOLOGY vol. 18, 124-124.
Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Britti D, Patel NSA, Paola RD, Genovese T et al.(2004). Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein. INTENS CARE MED vol. 30, (5) 951-956.
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Sepodes B, Maio R, Pinto R, Marques C, Mendes-Do-Vale J, McDonald MC, Thiemermann C, Mota-Filipe H (2004). Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia-reperfusion in the rat. TRANSPLANTATION PROCEEDINGS. vol. 36, 849-853.
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Cuzzocrea S, Dugo L, Patel NSA, Di Paola R, Cockerill GW, Genovese T, Thiemermann C(2004). High-density lipoproteins reduce the intestinal damage associated with ischemia/reperfusion and colitis. SHOCK vol. 21, (4) 342-351.
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Chatterjee PK, Patel NSA, Kvale EO, Brown PAJ, Stewart KN, Mota-Filipe H, Sharpe MA, Di Paola R et al.(2004). EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney. Am J Nephrol vol. 24, (2) 165-177.
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Wu AH, Hinds CJ, Thiemermann C(2004). High-density lipoproteins in sepsis and septic shock: Metabolism, actions, and therapeutic applications. SHOCK vol. 21, (3) 210-221.
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Myhre AE, Stuestol JF, Dahle MK, Overland G, Thiemermann C, Foster SJ, Lilleaasen P, Aasen AO et al.(2004). Organ injury and cytokine release caused by peptidoglycan are dependent on the structural integrity of the glycan chain. INFECT IMMUN vol. 72, (3) 1311-1317.
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Al-Ghamdi SS, Chatterjee PK, Raftery MJ, Thiemermann C, Yaqoob MM(2004). Role of cytochrome P4502E1 activation in proximal tubular cell injury induced by hydrogen peroxide. Ren Fail vol. 26, (2) 103-110.
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Collin M, Patel NSA, Dugo L, Thiemermann C(2004). Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxy Delta(12,14) prostaglandin J(2) against the multiple organ failure caused by endotoxin. CRIT CARE MED vol. 32, (3) 826-831.
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Collin M, Abdelrahman M, Thiemermann C(2004). Endogenous ligands of PPAR-gamma reduce the liver injury in haemorrhagic shock. Eur J Pharmacol vol. 486, (2) 233-235.
10.1016/j.ejphar.2003.12.032
Chatterjee PK, Patel NSA, Cuzzocrea S, Brown PAJ, Stewart KN, Mota-Filipe H, Britti D, Eberhardt W et al.(2004). The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure. Cardiovasc Res vol. 61, (3) 630-643.
10.1016/j.cardiores.2003.10.024
Chatterjee PK, Chatterjee BE, Pedersen H, Sivarajah A, McDonald MC, Mota-Filipe H, Brown PAJ, Stewart KN et al.(2004). 5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion. Kidney Int vol. 65, (2) 499-509.
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Wang JE, Dahle MK, Yndestad A, Bauer I, McDonald MC, Aukrust P, Foster SJ, Bauer M et al.(2004). Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat. CRIT CARE MED vol. 32, (2) 546-552.
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Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Patel NSA, Di Paola R, Genovese T, Chatterjee PK et al.(2004). Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice. CRIT CARE MED vol. 32, (2) 457-466.
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THIEMERMANN C, Cuzzocrea S, Genovese T, Di Paola R, Caputi AP, Threadgill M(2004). Benefical effects of 5-aminoisoquinolinone, a novel, potent, water-soluable, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occulsion and reperfusion. European Journal of Pharmacology vol. 492, 203-210.
10.1016/j.ejphar.2004.03.033
Marzocco S, Di Paola R, Autore G, Mazzon E, Pinto A, Caputi AP, Thiemermann C, Cuzzocrea S(2004). Calpain inhibitor I reduces intestinal ischemia-reperfusion injury in the rat. SHOCK vol. 21, (1) 38-44.
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Hadley JS, Wang JE, Foster SJ, Thiemermann C, Hinds CJ (2004). Cytokine responses to combined administration of lipopolysaccharide (LPS) and peptidoglycan (PepG). SHOCK. vol. 21, 50-50.
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Sepodes B, Pinto R, McDonald MC, Thiemermann C, Mota-Filipe H (2004). Effect of recombinant human erythropoietin in a rat model of ischemia-reperfusion injury of the liver. SHOCK. vol. 21, 87-87.
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Thiemermann C(2004). Ligands of the peroxisome proliferator-activated receptor-gamma and heart failure. Br J Pharmacol vol. 141, (1) 1-3.
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Hadley JS, Wang JE, Foster SJ, Thiemermann C, Hinds CJ (2004). Monocyte cell surface receptor upregulation in response to stimulation with lipopolysaccharide and peptidoglycan. SHOCK. vol. 21, 21-21.
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Wang JE, Dahle MK, Aasen AO, Foster SJ, Thiemermann C (2004). Peptidoglycan causes local and systemic inflammation in the rat. SHOCK. vol. 21, 148-148.
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THIEMERMANN C, Salvemini D, Cuzzocrea S(2004). Potential therapeutic effect of antioxidant therapy in shock and inflammation. Curr. Medicinal Chemistry vol. 11, 1147-1162.
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Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Maffia P, Patel NSA, Di Paola R, Ialenti A et al.(2004). Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation. EUR J PHARMACOL vol. 483, (1) 79-93.
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Chatterjee PK, di Villa Bianca RD, Sivarajah A, McDonald MC, Cuzzocrea S, Thiemermann C(2003). Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney. Eur J Pharmacol vol. 482, (1-3) 271-280.
10.1016/j.ejphar.2003.09.071
Keller T, Pleskova M, McDonald MC, Thiemermann C, Pfeilschifter J, Beck KF(2003). Identification of manganese superoxide dismutase as a NO-regulated gene in rat glomerular mesangial cells by 2D gel electrophoresis. NITRIC OXIDE-BIOL CH vol. 9, (4) 183-193.
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McDonald MC, Dhadly P, Cockerill GW, Cuzzocrea S, Mota-Filipe H, Hinds CJ, Miller NE, Thiemermann C(2003). Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock. Shock vol. 20, (6) 551-557.
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Cuzzocrea S, Mazzon E, Dugo L, Patel NSA, Serraino I, Di Paola R, Genovese T, Britti D et al.(2003). Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma. ARTHRITIS RHEUM vol. 48, (12) 3544-3556.
10.1002/art.11351
Sharples EJ, Patel N, Brown P, Stewart K, Mota-Philipe H, Sheaff M, Allen DA, Harwood SM et al. (2003). Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion injury by the inhibition of the caspase cascade and apoptosis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. vol. 14, 273A-273A.
Wang JE, Dahle MK, McDonald M, Foster SJ, Aasen AO, Thiemermann C(2003). Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism. Shock vol. 20, (5) 402-414.
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Cuzzocrea S, McDonald MC, Mazzon E, Filipe HM, Costantino G, Caputi AP, Thiemermann C(2000). Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of splanchnic artery occlusion and reperfusion. SHOCK vol. 14, (2) 150-156.
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Thiemermann C(2000). Inhibition of the activity of poly (ADP-ribose) polymerase in ischemia-reperfusion injury - Editorial comment. SHOCK vol. 14, (2) 142-143.
10.1097/00024382-200014020-00011
Ruetten H, Thiemermann C, Perretti M(1999). Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-κB but not protein tyrosine kinase: Comparison to induction of iNOS. Mediators of Inflammation vol. 8, (2) 77-84.
10.1080/09629359990568
Wu CC, Croxtall JD, Perretti M, Bryant CE, Thiemermann C, Flower RJ, Vane JR(1995). Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proceedings of the National Academy of Sciences of the United States of America vol. 92, (8) 3473-3477.
10.1073/pnas.92.8.3473
Perretti M, Szabó C, Thiemermann C(1995). Effect of interleukin‐4 and interleukin‐10 on leucocyte migration and nitric oxide production in the mouse. British Journal of Pharmacology vol. 116, (4) 2251-2257.
10.1111/j.1476-5381.1995.tb15061.x
Wu CC, Szabó C, Chen SJ, Thiemermann C, Vane JR(1994). Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin. Biochemical and Biophysical Research Communications vol. 201, (1) 436-442.
10.1006/bbrc.1994.1720
Szabó C, Thiemermann C, Wu CC, Perretti M, Vane JR(1994). Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proceedings of the National Academy of Sciences of the United States of America vol. 91, (1) 271-275.
10.1073/pnas.91.1.271
Thiemermann C, Wu C, Szabó C, Perretti M, Vane JR(1993). Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. British Journal of Pharmacology vol. 110, (1) 177-182.
10.1111/j.1476-5381.1993.tb13789.x
Hecker M, Mitchell JA, Harris HJ, Katsura M, Thiemermann C, Vane JR (1990). N(G)-monomethyl-L-arginine but not N(ω)-nitro-L-arginine is metabolized by endothelial cells to L-citrulline. European Journal of Pharmacology. vol. 183, 648-649.
10.1016/0014-2999(90)93576-C
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