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Publications:  Dr Manish Saxena

Colonna P, von Heymann C, Santamaria A, Saxena M, Vanassche T, Wolpert D, Laeis P, Wilkins R et al.(2020). Routine clinical practice in the periprocedural management of edoxaban therapy is associated with low risk of bleeding and thromboembolic complications: The prospective, observational, and multinational EMIT-AF/VTE study. Clinical Cardiology
10.1002/clc.23379
Azizi M, Schmieder RE, Mahfoud F, Weber MA, Daemen J, Lobo MD, Sharp ASP, Bloch MJ et al.(2019). Six-Month Results of Treatment-Blinded Medication Titration for Hypertension Control After Randomization to Endovascular Ultrasound Renal Denervation or a Sham Procedure in the RADIANCE-HTN SOLO Trial. Circulation vol. 139, (22) 2542-2553.
10.1161/CIRCULATIONAHA.119.040451
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61550
McGuire DK, Alexander JH, Johansen OE, Perkovic V, Rosenstock J, Cooper ME, Wanner C, Kahn SE et al.(2019). Linagliptin Effects on Heart Failure and Related Outcomes in Individuals With Type 2 Diabetes Mellitus at High Cardiovascular and Renal Risk in CARMELINA. Circulation vol. 139, (3) 351-361.
10.1161/CIRCULATIONAHA.118.038352
Rosenstock J, Perkovic V, Johansen OE, Cooper ME, Kahn SE, Marx N, Alexander JH, Pencina M et al.(2019). Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial. JAMA vol. 321, (1) 69-79.
10.1001/jama.2018.18269
Lobo MD, Sharp ASP, Kapil V, Davies J, De Belder MA, Cleveland T, Bent C, Chapman N et al.(2019). Joint UK societies' 2019 consensus statement on renal denervation. Heart
10.1136/heartjnl-2019-315098
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59562
Sharp ASP, Saxena M, Lobo MD(2018). Renal artery sympathetic denervation: Back on track!. Eur Heart J vol. 39, (46) 4056-4057.
10.1093/eurheartj/ehy718
Mukhtar O, Cheriyan J, Cockcroft JR, Collier D, Coulson JM, Dasgupta I, Faconti L, Glover M et al.(2018). A randomized controlled crossover trial evaluating differential responses to antihypertensive drugs (used as mono- or dual therapy) on the basis of ethnicity: The comparIsoN oF Optimal Hypertension RegiMens; part of the Ancestry Informative Markers in HYpertension program—AIM-HY INFORM trial. American Heart Journal vol. 204, 102-108.
10.1016/j.ahj.2018.05.006
Saxena M, Shour T, Shah M, Wolff CB, Julu POO, Kapil V, Collier DJ, Ng FL et al.(2018). Attenuation of Splanchnic Autotransfusion Following Noninvasive Ultrasound Renal Denervation: A Novel Marker of Procedural Success. J Am Heart Assoc vol. 7, (12)
10.1161/JAHA.118.009151
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43325
Azizi M, Schmieder RE, Mahfoud F, Weber MA, Daemen J, Davies J, Basile J, Kirtane AJ et al.(2018). Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial. The Lancet vol. 391, (10137) 2335-2345.
10.1016/S0140-6736(18)31082-1
Williams B, MacDonald TM, Morant SV, Webb DJ, Sever P, McInnes GT, Ford I, Cruickshank JK et al.(2018). Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies. The Lancet Diabetes and Endocrinology vol. 6, (6) 464-475.
10.1016/S2213-8587(18)30071-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/47823
Saxena M, Sobotka P, Balmforth P, Mathur A, Jain A, Rensing B, Lobo M (2018). IMMEDIATE, SIGNIFICANT DECLINE IN CENTRAL AND PERIPHERAL BLOOD PRESSURE WITH CENTRAL ARTERIAL VENOUS ANASTOMOSIS. JOURNAL OF HYPERTENSION. vol. 36, E288-E288.
10.1097/01.hjh.0000539838.93061.2c
Schmieder RE, Ott C, Toennes SW, Bramlage P, Gertner M, Dawood O, Baumgart P, O'Brien B et al. (2018). Phase II randomized sham-controlled study of renal denervation for individuals with uncontrolled hypertension - WAVE IV. J Hypertens. vol. 36, 680-689.
10.1097/HJH.0000000000001584
Lobo MD, Ott C, Sobotka PA, Saxena M, Stanton A, Cockcroft JR, Sulke N, Dolan E et al.(2017). Central Iliac Arteriovenous Anastomosis for Uncontrolled Hypertension: One-Year Results From the ROX CONTROL HTN Trial. Hypertension vol. 70, (6) 1099-1105.
10.1161/HYPERTENSIONAHA.117.10142
MacDonald TM, Williams B, Webb DJ, Morant S, Caulfield M, Cruickshank JK, Ford I, Sever P et al.(2017). Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial. J Am Heart Assoc vol. 6, (11)
10.1161/JAHA.117.006986
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34993
Saxena M, Shour T, Shah M, Wolff C, Collier DJ, Kapil V, Balawon A, Pheby JM et al. (2017). Attenuation of splanchnic autotransfusion following non-invasive ultrasound renal denervation: a novel marker of procedural success. JOURNAL OF HUMAN HYPERTENSION. vol. 31, 679-680.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64765
Saxena M, Shour T, Sobotka P, Jain A, Collier DJ, Hamshere S, Mathur A, Knight C et al. (2017). ANTIHYPERTENSIVE EFFECTS OF A CENTRAL ARTERIOVENOUS ANASTOMOSIS ARE MEDIATED THROUGH PROFOUND REDUCTION IN SYSTEMIC VASCULAR RESISTANCE. JOURNAL OF HYPERTENSION. vol. 35, E293-E294.
10.1097/01.hjh.0000523858.47322.9b
Saxena M, Shour T, Shah M, Wolff C, Collier DJ, Kapil V, Balawon A, Pheby JM et al. (2017). ATTENUATION OF SPLANCHNIC AUTOTRANSFUSION FOLLOWING NON-INVASIVE ULTRASOUND RENAL DENERVATION: A NOVEL MARKER OF PROCEDURAL SUCCESS. JOURNAL OF HYPERTENSION. vol. 35, E77-E78.
10.1097/01.hjh.0000523177.11308.8c
Schmieder RE, Ott C, Toennes S, Gertner M, Dawood O, Saxena M, O'Brien B, Lobo M (2017). PHASE II RANDOMIZED SHAM-CONTROLLED STUDY OF RENAL DENERVATION FOR SUBJECTS WITH UNCONTROLLED HYPERTENSION - WAVE IV. JOURNAL OF HYPERTENSION. vol. 35, E21-E21.
10.1097/01.hjh.0000523035.88901.5a
Ormiston J, Neuzil P, O'brien B, Saxena M, Schmieder RE, Gertner M, Dawood O, Lobo M (2017). REDO RENAL DENERVATION WITH NON-INVASIVE THERAPEUTIC ULTRASOUND. JOURNAL OF HYPERTENSION. vol. 35, E213-E213.
10.1097/01.hjh.0000523603.68539.48
Lobo M, Montarello J, Saxena M, Jain A, Walters D, Pincus M, Worthley S (2017). RENAL DENERVATION USING THE ENLIGHTN RENAL DENERVATION SYSTEM IN ALTERNATIVE HYPERTENSIVE POPULATIONS: 36 MONTH BLOOD PRESSURE RESULTS FROM ENLIGHTN II STUDY. JOURNAL OF HYPERTENSION. vol. 35, E213-E213.
10.1097/01.hjh.0000523604.76163.e8
Ott C, Lobo MD, Sobotka PA, Mahfoud F, Stanton A, Cockcroft J, Sulke N, Dolan E et al.(2016). Effect of Arteriovenous Anastomosis on Blood Pressure Reduction in Patients With Isolated Systolic Hypertension Compared With Combined Hypertension. J Am Heart Assoc vol. 5, (12)
10.1161/JAHA.116.004234
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34387
Floyd CN, Adeel MY, Wolff CB, Julu P, Shah M, Collier DJ, Saxena M, Brier T et al.(2016). First-in-man treatment of severe blood pressure variability with baroreflex activation therapy. International Journal of Cardiology vol. 220, Article C, 577-579.
10.1016/j.ijcard.2016.06.308
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64021
Wolff C, Julu PO, Collier DJ, Saxena M, Kapil V, Shah M, Eftychiou S, Mills E et al. (2016). EFFECTS OF MILD DYNAMIC EXERCISE ON CIRCULATORY AND AUTONOMIC FUNCTION IN HEALTHY VOLUNTEERS. JOURNAL OF HYPERTENSION. vol. 34, E351-E352.
10.1097/01.hjh.0000492374.65972.56
Lobo MD, Montarello J, Saxena M, Jain AK, Walters D, Pincus M, Worthley SG (2016). RENAL DENERVATION USING THE ENLIGHTN RENAL DENERVATION SYSTEM IN ALTERNATIVE HYPERTENSIVE POPULATIONS: 24 MONTH RESULTS FROM THE ENLIGHTN II STUDY. JOURNAL OF HYPERTENSION. vol. 34, E276-E276.
10.1097/01.hjh.0000492141.86216.8b
Lobo MD, Montarello J, Saxena M, Jain A, Walters D, Pincus M, Tsioufis C, Papademetriou V et al.(2016). [OP.4C.04] SAFETY AND PERFORMANCE OF THE ENLIGHTN RENAL DENERVATION SYSTEM IN PATIENTS WITH DRUG-RESISTANT HYPERTENSION: POOLED ANALYSES FROM THE ENLIGHTN 1, 2 AND 3 TRIALS. J Hypertens vol. 34 Suppl 2,
10.1097/01.hjh.0000491460.20240.18
Lobo MD, Adeel MY, Wolff CB, Julu PO, Shah M, Collier DM, Saxena M, Floyd C et al.(2016). [OP.8D.02] FIRST IN MAN TREATMENT OF SEVERE BP VARIABILITY WITH BAROREFLEX ACTIVATION THERAPY. J Hypertens vol. 34 Suppl 2, e105-e105.
10.1097/01.hjh.0000491609.58838.67
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61614
Lobo M, Saxena M, Sobotka PA, Ott C, Dolan E, Foran J, Furniss SS, Cockcroft J et al.(2016). [OP.LB.02.04] CENTRAL ILIAC ARTERIOVENOUS ANASTOMOSIS FOR UNCONTROLLED HYPERTENSION: 12 MONTH FOLLOW UP RESULTS OF THE ROX CONTROL HTN RANDOMISED CONTROLLED TRIAL. J Hypertens vol. 34 Suppl 2, e78-e79.
10.1097/01.hjh.0000491540.41256.05
Saxena M, Sobotka PA, Hamshere SM, Jain A, Mathur A, Knight C, Collier DJ, Lobo MD(2016). Antihypertensive effects of a central arteriovenous anastomosis are mediated through profound reduction in systemic vascular resistance. Circulation: Cardiovascular Interventions vol. 9, (8)
10.1161/CIRCINTERVENTIONS.116.004012
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64062
Ng FL, Saxena M, Mahfoud F, Pathak A, Lobo MD(2016). Device-based Therapy for Hypertension. Curr Hypertens Rep vol. 18, (8) 61-61.
10.1007/s11906-016-0670-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32164
Burchell AE, Chan K, Ratcliffe LEK, Hart EC, Saxena M, Collier DJ, Jain AK, Mathur A et al.(2016). Controversies Surrounding Renal Denervation: Lessons Learned From Real-World Experience in Two United Kingdom Centers. Journal of Clinical Hypertension vol. 18, (6) 585-592.
10.1111/jch.12789
De Jager RL, Sanders MF, Bots ML, Lobo MD, Ewen S, Beeftink MMA, Böhm M, Daemen J et al.(2016). Renal denervation in hypertensive patients not on blood pressure lowering drugs. Clinical Research in Cardiology vol. 105, (9) 755-762.
10.1007/s00392-016-0984-y
Saxena M, Antoniou S, Hamedi N, Robinson P, Singh H, Mukhtar O, Kapil V, Lobo MD(2016). Multiple drug-intolerant hypertension: A case series utilising a novel-treatment algorithm. British Journal of General Practice vol. 66, (645) e285-e287.
10.3399/bjgp16X684709
Antoniou S, Saxena M, Hamedi N, de Cates C, Moghul S, Lidder S, Kapil V, Lobo MD(2016). Management of Hypertensive Patients With Multiple Drug Intolerances: A Single-Center Experience of a Novel Treatment Algorithm. Journal of Clinical Hypertension vol. 18, (2) 129-138.
10.1111/jch.12637
Wolff CB, Collier DJ, Shah M, Saxena M, Brier TJ, Kapil V, Green D, Lobo M(2016). A discussion on the regulation of blood flow and pressure. Advances in Experimental Medicine and Biology vol. 876, 129-135.
10.1007/978-1-4939-3023-4_16
Worthley SG, Montarello J, Saxena M, Jain A, Walters D, Pincus MW, Tsioufis KP, Papademetriou V et al. (2015). Safety and Performance of the EnligHTN (TM) Renal Denervation System in Patients with Drug-resistant Hypertension: Pooled analyses from the EnligHTN I, II and III trials. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 66, B315-B315.
10.1016/j.jacc.2015.08.798
Lobo M, Montarello J, Saxena M, Jain A, Walters D, Pincus MW, Worthley SG (2015). Safety and Performance of the EnligHTN Renal Denervation System in Patients with Severe Uncontrolled Hypertension: 12 Month Results from the EnligHTN II Study. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 66, B39-B40.
10.1016/j.jacc.2015.08.129
Lobo M, Montarello J, Saxena M, Jain A, Walters D, Pincus MW, Worthley SG (2015). Safety and Performance of the EnligHTN Renal Denervation System in Patients with Uncontrolled Hypertension and Chronic Kidney Disease: 12 Month Results from the EnligHTN II Study. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 66, B313-B314.
10.1016/j.jacc.2015.08.795
Saxena M, Collier D, Jain A, Mathur A, Knight C, Sobotka P, Lobo M(2015). A central iliac arteriovenous anastomosis results in durable and substantial blood pressure reduction in a woman with uncontrolled hypertension and multiple antihypertensive drug intolerances. JOURNAL OF HUMAN HYPERTENSION vol. 29, (10) 631-632.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11059
Lobo MD, Montarello J, Saxena M, Jain AK, Walters D, Pincus M, Worthley SG(2015). Safety and performance of the EnligHTN renal denervation system in patients with severe uncontrolled hypertension: 12 month results from the EnligHTN II Study. JOURNAL OF HUMAN HYPERTENSION vol. 29, (10) 631-631.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11060
Kapil V, Sobotka PA, Saxena M, Mathur A, Knight C, Dolan E, Stanton A, Lobo MD(2015). Central Iliac Arteriovenous Anastomosis for Hypertension: Targeting Mechanical Aspects of the Circulation. Current Hypertension Reports vol. 17, (9)
10.1007/s11906-015-0585-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11058
Burchell AE, Chan K, Hart EC, Saxena M, Jain AK, Collier DJ, Paton JFR, Nightingale AK et al. (2015). Challenges facing renal denervation: insight from real world experience at two UK centres. EUROPEAN HEART JOURNAL. vol. 36, 505-506.
Saxena M, Collier D, Jain A, Knight C, Mathur A, Sobotka P, Lobo M (2015). A CENTRAL ILIAC ARTERIOVENOUS ANASTOMOSIS RESULTS IN DURABLE AND SUBSTANTIAL BLOOD PRESSURE REDUCTION IN A WOMAN WITH UNCONTROLLED HYPERTENSION AND MULTIPLE DRUG INTOLERANCES. JOURNAL OF HYPERTENSION. vol. 33, E112-E112.
10.1097/01.hjh.0000467654.38661.31
Antoniou S, Saxena M, Hamedi N, De Cates C, Moghul S, Lidder S, Lobo M, Kapil V (2015). MANAGEMENT OF HYPERTENSIVE PATIENTS WITH MULTIPLE DRUG INTOLERANCES: A SINGLE-CENTRE EXPERIENCE OF A NOVEL TREATMENT ALGORITHM. JOURNAL OF HYPERTENSION. vol. 33, E328-E328.
10.1097/01.hjh.0000468387.93679.ef
Worthley S, Montarello J, Saxena M, Jain A, Walters D, Pincus M, Tsioufis C, Papademetriou V et al. (2015). SAFETY AND PERFORMANCE OF THE ENLIGHTN (TM) RENAL DENERVATION SYSTEM IN PATIENTS WITH DRUG-RESISTANT HYPERTENSION: POOLED ANALYSES FROM THE ENLIGHTN I, II AND III TRIALS. JOURNAL OF HYPERTENSION. vol. 33, E359-E359.
Lobo M, Saxena M, Jain A, Walters D, Pincus M, Montarello J, Worthley S (2015). SAFETY AND PERFORMANCE OF THE ENLIGHTN RENAL DENERVATION SYSTEM IN PATIENTS WITH MODERATE UNCONTROLLED HYPERTENSION: 12 MONTH RESULTS FROM THE ENLIGHTN II STUDY. JOURNAL OF HYPERTENSION. vol. 33, E363-E364.
Lobo M, Saxena M, Jain AJ, Walters D, Pincus M, Montarello J, Worthley SG (2015). SAFETY AND PERFORMANCE OF THE ENLIGHTN RENAL DENERVATION SYSTEM IN PATIENTS WITH SEVERE UNCONTROLLED HYPERTENSION: 12 MONTH RESULTS FROM THE ENLIGHTN II STUDY. JOURNAL OF HYPERTENSION. vol. 33, E51-E51.
10.1097/01.hjh.0000467483.82320.f7
Lobo M, Saxena M, Jain A, Walters D, Pincus M, Montarello J, Worthley S (2015). SAFETY AND PERFORMANCE OF THE ENLIGHTN RENAL DENERVATION SYSTEM IN PATIENTS WITH UNCONTROLLED HYPERTENSION AND CHRONIC KIDNEY DISEASE: 12 MONTH RESULTS FROM THE ENLIGHTN II STUDY. JOURNAL OF HYPERTENSION. vol. 33, E363-E363.
Saxena M, Antoniou S, Hamedi N, Chowdhury R, Lidder S, Brier T, Robinson P, Kapil V et al.(2014). Anti-hypertensive medicine intolerance - an overlooked and important cause of failed compliance. JOURNAL OF HUMAN HYPERTENSION vol. 28, (10) 633-633.
Saxena M, Jain A, Mathur A, Knight C, Caulfield M, Collier D, Lobo M (2014). Early reduction in blood pressure and heart rate variability following multielectrode radio-frequency renal denervation in medicines intolerant patients. JOURNAL OF HUMAN HYPERTENSION. vol. 28, 647-647.
Burchell A, Chan K, Ratcliffe L, Hart E, Saxena M, Collier D, Jain A, Mathur A et al. (2014). Highly variable response to renal denervation for resistant hypertension - real world experience from 2 UK centres. JOURNAL OF HUMAN HYPERTENSION. vol. 28, 645-646.
Antoniou S, Hamedi N, Choudhury R, Lidder S, Saxena M, Brier T, Robinson P, Kapil V et al.(2014). Management of uncontrolled blood pressure in patients referred to a specialist hypertension clinic with multiple medicines intolerance. JOURNAL OF HUMAN HYPERTENSION vol. 28, (10) 645-645.
Saxena M, Collier D, Caulfield M, Lobo M(2012). Patients with resistant hypertension warrant a trial of salt restriction before and after renal denervation (RD). JOURNAL OF HUMAN HYPERTENSION vol. 26, (10) 619-619.
Chan K, Ng FL, Saxena M, Collier D, Matson M, Jain A, Caulfield M, Lobo M(2012). Renal denervation in resistant hypertension-a prospective case series. JOURNAL OF HUMAN HYPERTENSION vol. 26, (10) 631-631.
Collier DJ, Robson J, Scott R, Will CM, Eldridge SE, Griffiths CJ, Badrick E, Saxena M et al.(2010). HiLo: a health services intervention study: methods and interim results on the first 2000 patients at 1 year. J HUM HYPERTENS vol. 24, (10) 708-709.
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