Publications:  Prof Mauro Perretti

Hebeda CB, Sandri S, Benis CM, Paula-Silva MD, Loiola RA, Reutelingsperger C, Perretti M, Farsky SHP(2020). Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst. Cells vol. 9, (5)

Corsiero E, Carlotti E, Jagemann L, Perretti M, Pitzalis C, Bombardieri M(2020). H and L chain affinity maturation and/or Fab N-glycosylation influence immunoreactivity toward neutrophil extracellular trap antigens in rheumatoid arthritis synovial b cell clones. Journal of Immunology vol. 204, (9) 2374-2379.

Norling LV, Perretti M(2020). Proresolving lipid mediators enhance PMN-mediated bacterial clearance. Proceedings of the National Academy of Sciences of the United States of America vol. 117, (17) 9148-9150.

McArthur S, Juban G, Gobbetti T, Desgeorges T, Theret M, Gondin J, Toller-Kawahisa JE, Reutelingsperger CP et al.(2020). Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation. Journal of Clinical Investigation vol. 130, (3) 1156-1167.

Belvedere R, Pessolano E, Porta A, Tosco A, Parente L, Petrella F, Perretti M, Petrella A(2020). Mesoglycan induces the secretion of microvesicles by keratinocytes able to activate human fibroblasts and endothelial cells: A novel mechanism in skin wound healing. European Journal of Pharmacology vol. 869,

Topping LM, Thomas BL, Rhys HI, Tremoleda JL, Foster M, Seed M, Voisin MB, Vinci C et al.(2020). Targeting Extracellular Vesicles to the Arthritic Joint Using a Damaged Cartilage-Specific Antibody. Frontiers in Immunology vol. 11,

Montero Melendez T, Nagano A, Chelala C, Filer A, Buckley CD, Perretti M(2020). Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis. Nature Communications vol. 11, (1) Article 745,

Machado MG, Tavares LP, Souza GVS, Queiroz-Junior CM, Ascenção FR, Lopes ME, Garcia CC, Menezes GB et al.(2020). The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia. FASEB Journal vol. 34, (2) 2749-2764.

Piras G, Rattazzi L, Paschalidis N, Oggero S, Berti G, Ono M, Bellia F, D'Addario C et al.(2020). Immuno-moodulin: A new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells. Brain, Behavior, and Immunity

Barbosa CMV, Fock RA, Hastreiter AA, Reutelingsperger C, Perretti M, Paredes-Gamero EJ, Farsky SHP(2019). Extracellular annexin-A1 promotes myeloid/granulocytic differentiation of hematopoietic stem/progenitor cells via the Ca²⁺/MAPK signalling transduction pathway. Cell Death Discovery vol. 5, (1)

Bizzarro V, Belvedere R, Pessolano E, Parente L, Petrella F, Perretti M, Petrella A(2019). Mesoglycan induces keratinocyte activation by triggering syndecan-4 pathway and the formation of the annexin A1/S100A11 complex. Journal of Cellular Physiology vol. 234, (11) 20174-20192.

Everts-Graber J, Martin KR, Thieblemont N, Mocek J, Roccabianca A, Chafey P, Le Gall M, Tacnet-Delorme P et al.(2019). Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance. Kidney International vol. 96, (2) 397-408.

Senchenkova EY, Ansari J, Becker F, Vital SA, Al-Yafeai Z, Sparkenbaugh EM, Pawlinski R, Stokes KY et al.(2019). Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation. Circulation vol. 140, (4) 319-335.

Salamah MF, Ravishankar D, Vaiyapuri R, Moraes LA, Patel K, Perretti M, Gibbins JM, Vaiyapuri S(2019). The formyl peptide fMLF primes platelet activation and augments thrombus formation. Journal of Thrombosis and Haemostasis vol. 17, (7) 1120-1133.

Nadkarni S, Lashin H, Hollywood J, Dasgupta B, Mason JC, Perretti M(2019). Identification of an activated neutrophil phenotype in polymyalgia rheumatica during steroid treatment: A potential involvement of immune cell cross-talk. Clinical Science vol. 133, (7) 839-851.

VOISIN M, leoni G, WOODFIN A, loumagne L, PATEL N, Di Paola R, Cuzzocrea S, THIEMERMANN C et al.(2019). Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post ischemia/reperfusion injury. Journal of Pathology vol. 248, (1) 88-102.

Di Paola R, Fusco R, Gugliandolo E, D'Amico R, Cordaro M, Impellizzeri D, Perretti M, Cuzzocrea S(2019). Formyl peptide receptor 1 signalling promotes experimental colitis in mice. Pharmacological Research vol. 141, 591-601.

Sugimoto MA, Vago JP, Perretti M, Teixeira MM(2019). Mediators of the Resolution of the Inflammatory Response. Trends in Immunology vol. 40, (3) 212-227.

de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M, Chen J, Cacace A, Hams E et al.(2019). Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A<inf>4</inf> mimetics (sLXms). European Journal of Medicinal Chemistry vol. 162, 80-108.

Sinniah A, Yazid S, Bena S, Oliani SM, Perretti M, Flower RJ(2019). Endogenous annexin-A1 negatively regulates mast cell-mediated allergic reactions. Frontiers in Pharmacology vol. 10,

Vago JP, Sugimoto MA, Lima KM, Negreiros-Lima GL, Baik N, Teixeira MM, Perretti M, Parmer RJ et al.(2019). Plasminogen and the plasminogen receptor, PLG-R<inf>KT</inf>, regulate macrophage phenotypic, and functional changes. Frontiers in Immunology vol. 10, (JUN)

Pessolano E, Belvedere R, Bizzarro V, Franco P, De Marco I, Porta A, Tosco A, Parente L et al.(2018). Annexin A1 may induce pancreatic cancer progression as a key player of extracellular vesicles effects as evidenced in the in vitro MIA PaCa-2 model system. International Journal of Molecular Sciences vol. 19, (12)

Thomas BL, Perretti M(2018). Neutrophil wrap. Nature Nanotechnology vol. 13, (12) 1098-1099.

Petri MH, Thul S, Andonova T, Lindquist-Liljeqvist M, Jin H, Skenteris NT, Arnardottir H, Maegdefessel L et al.(2018). Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms. JACC: Basic to Translational Science vol. 3, (6) 719-727.

Salamah MF, Ravishankar D, Kodji X, Moraes LA, Williams HF, Vallance TM, Albadawi DA, Vaiyapuri R et al.(2018). The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances vol. 2, (21) 2973-2985.

Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K et al.(2018). n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis. Brain vol. 141, (11) 3130-3143.

Hebeda CB, Machado ID, Reif-Silva I, Moreli JB, Oliani SM, Nadkarni S, Perretti M, Bevilacqua E et al.(2018). Endogenous annexin A1 (AnxA1) modulates early-phase gestation and offspring sex-ratio skewing. Journal of Cellular Physiology vol. 233, (9) 6591-6603.

Patruno S, Garrido-Mesa J, Romano M, PERRETTI M, MONTERO MELENDEZ T(2018). Ligand bias and its association with pro-resolving actions of melanocortin drugs. Frontiers in Pharmacology vol. 9, (919)

PITZALIS C, CORSIERO E, JAGEMANN L, PERRETTI M, BOMBARDIERI M(2018). Characterization of a synovial B cell-derived 1 recombinant monoclonal antibody 2 targeting stromal calreticulin in the rheumatoid joints. Journal of Immunology

Piovezan AP, Perretti M(2018). Potential engagement of pathways of the resolution of inflammation as mechanism of action for plants on animal models. Journal of Ethnopharmacology vol. 221, 160-161.

Qin CX, Finlayson SB, Al-Sharea A, Tate M, De Blasio MJ, Deo M, Rosli S, Prakoso D et al.(2018). Erratum: Author Correction: Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo (Scientific reports (2017) 7 1 (16615)). Scientific reports vol. 8, (1)

Lashin HMS, Nadkarni S, Oggero S, Jones HR, Knight JC, Hinds CJ, Perretti M(2018). Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis. Shock vol. 49, (4) 393-401.

Rhys HI, Dell'Accio F, Pitzalis C, Moore A, Norling LV, Perretti M(2018). Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages. EBioMedicine vol. 29, 60-69.

Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al.(2018). Resolvins suppress tumor growth and enhance cancer therapy. Journal of Experimental Medicine vol. 215, (1) 115-140.

Perretti M, Norling LV(2017). Actions of SPM in regulating host responses in arthritis. Molecular Aspects of Medicine vol. 58, 57-64.

Qin CX, Finlayson SB, Ai-Sharea A, Tate M, De Blasio MJ, Deo M, Rosli S, Prakoso D et al.(2017). Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo. Sci Rep vol. 7, (1) 16615-16615.

Simeoli R, Montague K, Jones HR, Castaldi L, Chambers D, Kelleher JH, Vacca V, Pitcher T et al.(2017). Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma. Nat Commun vol. 8, (1) 1778-1778.

Petri MH, Laguna-Fernandez A, Arnardottir H, Wheelock CE, Perretti M, Hansson GK, Bäck M(2017). Aspirin-triggered lipoxin A4 inhibits atherosclerosis progression in apolipoprotein E^−/− mice. British Journal of Pharmacology vol. 174, (22) 4043-4054.

Lima KM, Vago JP, Caux TR, Negreiros-Lima GL, Sugimoto MA, Tavares LP, Arribada RG, Carmo AAF et al.(2017). The resolution of acute inflammation induced by cyclic AMP is dependent on Annexin A1. Journal of Biological Chemistry vol. 292, (33) 13758-13773.

Perretti M, Montero-Melendez T(2017). Resolution in an 'over-inflamed' era. Biochemist vol. 39, (4) 4-7.

Gittens BR, Bodkin JV, Nourshargh S, Perretti M, Cooper D(2017). Galectin-3: A positive regulator of leukocyte recruitment in the inflamed microcirculation. Journal of Immunology vol. 198, (11) 4458-4469.

Piovezan AP, Batisti AP, Benevides MLACS, Turnes BL, Martins DF, Kanis L, Duarte ECW, Cavalheiro AJ et al.(2017). Hydroalcoholic crude extract of Casearia sylvestris Sw. reduces chronic post-ischemic pain by activation of pro-resolving pathways. Journal of Ethnopharmacology vol. 204, 179-188.

PERRETTI M, Dalli J, Colas R, Federici Canova D, Gobbetti T(2017). Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection. Proceedings of the National Academy of Sciences of the United States of America vol. 114, (15) 3963-3968.

Perretti M, Di Filippo C, D'Amico M, Dalli J(2017). Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide. PLoS One vol. 12, (4) Article 0175786, e0175786-e0175786.

Brod S, Gobbetti T, Gittens B, Ono M, Perretti M, D'Acquisto F(2017). The impact of environmental enrichment on the murine inflammatory immune response. JCI insight vol. 2, (7)

Kaneva MK, Greco KV, Headland SE, Montero-Melendez T, Mori P, Greenslade K, Pitzalis C, Moore A et al.(2017). Identification of novel chondroprotective mediators in resolving inflammatory exudates. Journal of Immunology vol. 198, (7) 2876-2885.

Montero-Melendez T, Forfar RAE, Cook JM, Jerman JC, Taylor DL, Perretti M(2017). Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3. Cellular and Molecular Life Sciences vol. 74, (7) 1335-1345.

Perretti M, Cooper D, Dalli J, Norling LV(2017). Immune resolution mechanisms in inflammatory arthritis. Nat Rev Rheumatol vol. 13, (2) 87-99.

Simeoli R, Mattace Raso G, Pirozzi C, Lama A, Santoro A, Russo R, Montero-Melendez T, Berni Canani R et al.(2017). An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis. British Journal of Pharmacology vol. 174, (11) 1484-1496.

Bruzzi S, Sutti S, Toscani A, Bozzola C, Reutelingsperger C, Kusters D, Mcarthur S, Perretti M et al. (2017). Annexin A1 supplementation prevents the progression to fibrosis of nonalcoholic steatoepatitis (NASH). JOURNAL OF HEPATOLOGY. Conference: The International Liver Congress 2017 vol. 66, S608-S608.

NADKARNI SA, Smith J, Mauro C, Marelli-Berg FM, Perretti M, Sferruzzi-Perri AN, Ledwozyw A, Kishore M et al.(2016). Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy. Proceedings of the National Academy of Sciences of USA

Machado ID, Spatti M, Hastreiter A, Santin JR, Fock RA, Gil CD, Oliani SM, Perretti M et al.(2016). Annexin A1 Is a Physiological Modulator of Neutrophil Maturation and Recirculation Acting on the CXCR4/CXCL12 Pathway. Journal of Cellular Physiology vol. 231, (11) 2418-2427.

Di Perna L, Gesualdo C, Maisto R, Di Filippo C, Perretti M, Testa F, Rossi S, D'amico M et al. (2016). Activation of melanocortin receptors Mc1 and Mc5 attenuates retinal damage in experimental diabetic retinopathy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. vol. 57,

Madeira MFM, Queiroz-Junior CM, Montero-Melendez T, Werneck SMC, Correa JD, Soriani FM, Garlet GP, Souza DG et al.(2016). Melanocortin agonism as a viable strategy to control alveolar bone loss induced by oral infection. The FASEB Journal

Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN(2016). Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. Journal of Immunology vol. 197, (6) 2362-2368.

Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J et al.(2016). Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo. Annals of the Rheumatic Diseases vol. 75, (6) 1228-1235.

Norling L, Headland S, Dalli J, Arnardottir H, Jones H, Haworth O, Serhan C, Perretti M (2016). PRO-RESOLVING AND CARTILAGE-PROTECTIVE ACTIONS OF RESOLVIN D1 IN INFLAMMATORY ARTHRITIS. ANNALS OF THE RHEUMATIC DISEASES. Conference: EULAR vol. 75, 673-673.

MONTERO MELENDEZ T, Buckley CD, Filer A, Turner JD, Perretti M (2016). TARGETING SYNOVIAL FIBROBLASTS WITH MELANOCORTIN DRUGS. ANNALS OF THE RHEUMATIC DISEASES. Conference: Annual European Congress of Rheumatology EULAR 2016 vol. 75, 923-923.

Vital SA, Becker F, Holloway PM, Russell J, Perretti M, Granger DN, Gavins FNE(2016). Fpr2/ALX Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral Inflammation: Impact for Therapy in Cardiovascular Disease. Circulation Article CIRCULATIONAHA.115.0,

Chen J, Kieswich J, Chiazza F, Moyes A, Gobbetti T, Purvis G, Salvatori D, Patel N et al.(2016). IkB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD. Journal of the American Society of Nephrology

Brancaleone V, Esposito I, Gargiulo A, Vellecco V, Asimakopoulou A, Citi V, Calderone V, Gobbetti T et al.(2016). D -Penicillamine modulates hydrogen sulfide (H<inf>2</inf>S) pathway through selective inhibition of cystathionine-γ-lyase. British Journal of Pharmacology vol. 173, (9) 1556-1565.

Sugimoto MA, Sousa LP, Pinho V, Perretti M, Teixeira MM(2016). Resolution of Inflammation: What Controls Its Onset?. Frontiers in Immunology vol. 7,

Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al.(2016). Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis. JCI Insight vol. 1, (5)

Jones HR, Robb CT, Perretti M, Rossi AG(2016). The role of neutrophils in inflammation resolution. Seminars in Immunology vol. 28, (2) 137-145.

Sinniah A, Yazid S, Perretti M, Solito E, Flower RJ(2016). The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil. International Immunopharmacology vol. 32, 87-95.

Vago JP, Tavares LP, Sugimoto MA, Lima GLN, Galvaõ I, De Caux TR, Ia L, Ribeiro ALC et al.(2016). Proresolving actions of synthetic and natural protease inhibitors are mediated by annexin A1. Journal of Immunology vol. 196, (4) 1922-1932.

Rossi S, Maisto R, Gesualdo C, Trotta MC, Ferraraccio F, Kaneva MK, Getting SJ, Surace E et al.(2016). Activation of Melanocortin Receptors MC<inf>1</inf> and MC<inf>5</inf> Attenuates Retinal Damage in Experimental Diabetic Retinopathy. Mediators of Inflammation vol. 2016,

Headland SE, Jones HR, Norling LV, Kim A, Souza PR, Corsiero E, Gil CD, Nerviani A et al.(2015). Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis. Science Translational Medicine vol. 7, (315)

Canova DF, Pavlov AM, Norling LV, Gobbetti T, Brunelleschi S, Le Fauder P, Cenac N, Sukhorukov GB et al.(2015). Alpha-2-macroglobulin loaded microcapsules enhance human leukocyte functions and innate immune response. Journal of Controlled Release vol. 217, 284-292.

Perretti M, Leroy X, Bland EJ, Montero-Melendez T(2015). Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation. Trends in Pharmacological Sciences vol. 36, (11) 737-755.

Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NSA, Perretti M, Collino M, Yaqoob MM et al. (2015). THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE. SHOCK. vol. 44, 16-16.

Holloway PM, Durrenberger PF, Trutschl M, Cvek U, Cooper D, Orr AW, Perretti M, Getting SJ et al.(2015). Both MC<inf>1</inf> and MC<inf>3</inf> receptors provide protection from cerebral ischemia-reperfusion-induced neutrophil recruitment. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 35, (9) 1936-1944.

Kusters DHM, Chatrou ML, Willems BAG, De Saint-Hubert M, Bauwens M, Van Der Vorst E, Bena S, Biessen EAL et al.(2015). Pharmacological treatment with annexin A1 reduces atherosclerotic plaque burden in LDLR^-/- mice on Western Type Diet. PLoS ONE vol. 10, (6)

Trentin PG, Ferreira TPT, Arantes ACS, Ciambarella BT, Cordeiro RSB, Flower RJ, Perretti M, Martins MA et al.(2015). Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice. British Journal of Pharmacology vol. 172, (12) 3058-3071.

Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NS, Perretti M, Collino M, Yaqoob MM et al. (2015). THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE. SHOCK. vol. 43, 92-93.

Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Canova DF, Perretti M, Brunelleschi S(2015). Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen. Life Sciences vol. 126, 28-36.

Montero-Melendez T, Gobbetti T, Cooray SN, Jonassen TE, Perretti M(2015). Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol vol. 194, (7) 3381-3388.

Gobbetti T, Ducheix S, le Faouder P, Perez T, Riols F, Boue J, Bertrand-Michel J, Dubourdeau M et al.(2015). Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor. Br J Pharmacol vol. 172, (3) 910-923.

Flower RJ, Perretti M(2015). 'Annexins' themed section. British Journal of Pharmacology vol. 172, (7) 1651-1652.

Leoni G, Neumann PA, Kamaly N, Quiros M, Nishio H, Jones HR, Sumagin R, Hilgarth RS et al.(2015). Annexin A1'containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. Journal of Clinical Investigation vol. 125, (3) 1215-1227.

Petri MH, Laguna-Fernandez A, Tseng CN, Hedin U, Perretti M, Bäck M(2015). Aspirin-triggered 15-epi-lipoxin A<inf>4</inf> signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation. International Journal of Cardiology vol. 179, 370-372.

McArthur S, Gobbetti T, Kusters DHM, Reutelingsperger CP, Flower RJ, Perretti M(2015). Definition of a novel pathway centered on lysophosphatidic acid to recruit monocytes during the resolution phase of tissue inflammation. Journal of Immunology vol. 195, (3) 1139-1151.

Haas R, Smith J, Rocher-Ros V, Nadkarni S, Montero-Melendez T, D¿Acquisto F, Bland EJ, Bombardieri M et al.(2015). Lactate regulates metabolic and proinflammatory circuits in control of T cell migration and effector functions. PLoS Biology vol. 13, (7)

Fredman G, Kamaly N, Spolitu S, Milton J, Ghorpade D, Chiasson R, Kuriakose G, Perretti M et al.(2015). Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Science Translational Medicine vol. 7, (275)

Perretti M(2015). The resolution of inflammation: New mechanisms in patho-physiology open opportunities for pharmacology. Seminars in Immunology vol. 27, (3) 145-148.

Gobbetti T, Coldewey SM, Chen J, McArthur S, Le Faouder P, Cenac N, Flower RJ, Thiemermann C et al.(2014). Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proceedings of the National Academy of Sciences of the United States of America vol. 111, (52) 18685-18690.

Thompson D, McArthur S, Hislop JN, Flower RJ, Perretti M(2014). Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: association with cell protection from apoptosis. J Biol Chem vol. 289, (52) 36166-36178.

Gallo I, Rattazzi L, Piras G, Gobbetti T, Panza E, Perretti M, Dalley JW, D'Acquisto F(2014). Formyl peptide receptor as a novel therapeutic target for anxiety-related disorders. PLoS ONE vol. 9, (12)

Machado ID, Santin JR, Drewes CC, Gil CD, Oliani SM, Perretti M, Farsky SHP(2014). Alterations in the profile of blood neutrophil membrane receptors caused by in vivo adrenocorticotrophic hormone actions. Am J Physiol Endocrinol Metab vol. 307, (9) E754-E763.

Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, Tabas I, Perretti M (2014). Resolvin D1 Limits 5-lipoxygenase nuclear localization and Leukotriene B<inf>4</inf> synthesis by inhibiting a calciumactivated kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. vol. 111, 14530-14535.

Greco KV, Nalesso G, Kaneva MK, Sherwood J, Iqbal AJ, Moradi-Bidhendi N, Dell'Accio F, Perretti M(2014). Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin. Biochem Pharmacol vol. 91, (3) 348-358.

Brancaleone V, Mitidieri E, Flower RJ, Cirino G, Perretti M(2014). Annexin A1 mediates hydrogen sulfide properties in the control of inflammation. J Pharmacol Exp Ther vol. 351, (1) 96-104.

Burgmaier M, Schutters K, Willems B, Van der Vorst EPC, Kusters D, Chatrou M, Norling L, Biessen EAL et al.(2014). AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE vol. 18, (10) 2117-2124.

Lashin H, Nadkarni S, Hinds C, Perretti M (2014). IN PATIENTS WITH SEVERE SEPSIS MICROPARTICLE PROFILES DIFFER ACCORDING TO THE SOURCE OF INFECTION. INTENSIVE CARE MEDICINE. vol. 40, S239-S240.

Montero-Melendez T, Madeira MFM, Norling LV, Alsam A, Curtis MA, da Silva TA, Perretti M(2014). Association between periodontal disease and inflammatory arthritis reveals modulatory functions by melanocortin receptor type 3. Am J Pathol vol. 184, (8) 2333-2341.

Locatelli I, Sutti S, Jindal A, Vacchiano M, Bozzola C, Reutelingsperger C, Kusters D, Bena S et al.(2014). Endogenous Annexin A1 Is a Novel Protective Determinant in Nonalcoholic Steatohepatitis in Mice. HEPATOLOGY vol. 60, (2) 531-544.

Montero-Melendez T, Perretti M(2014). Gapdh gene expression is modulated by inflammatory arthritis and is not suitable for qPCR normalization. Inflammation vol. 37, (4) 1059-1069.

Ahmed TJ, Kaneva MK, Pitzalis C, Cooper D, Perretti M(2014). Resolution of inflammation: examples of peptidergic players and pathways. Drug Discov Today vol. 19, (8) 1166-1171.

Cash JL, Norling LV, Perretti M(2014). Resolution of inflammation: targeting GPCRs that interact with lipids and peptides. Drug Discov Today vol. 19, (8) 1186-1192.

Farsky SHP, Santin JR, Takahama C, Machado ID, Teixeira S, Muscara MN, Pitta IR, Solito E et al. (2014). ANNEXIN A1 AND PPAR gamma ON RESOLUTION OF INFLAMMATION. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. vol. 115, 286-286.

Montero-Melendez T, Perretti M(2014). Connections in pharmacology: innovation serving translational medicine. Drug Discov Today vol. 19, (7) 820-823.

Headland SE, Jones HR, D'Sa ASV, Perretti M, Norling LV(2014). Cutting-edge analysis of extracellular microparticles using ImageStream(X) imaging flow cytometry. Sci Rep vol. 4,

Hardy W, Wright F, Hawtree S, Fearon U, Veale D, Perretti M, Wilson A, Muthana M (2014). HYPOXIA-INDUCIBLE FACTOR 2a REGULATES MACROPHAGE FUNCTION IN RHEUMATOID ARTHRITIS. ANNALS OF THE RHEUMATIC DISEASES. vol. 73, 174-174.

Old EA, Nadkarni S, Grist J, Gentry C, Bevan S, Kim K-W, Mogg AJ, Perretti M et al.(2014). Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. JOURNAL OF CLINICAL INVESTIGATION vol. 124, (5) 2023-2036.

Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M (2014). NEUTROPHILS IN GCA. RHEUMATOLOGY. vol. 53, 9-9.

Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ et al.(2014). Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation. Nat Commun vol. 5,

Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M(2014). Investigational analysis reveals a potential role for neutrophils in giant-cell arteritis disease progression. Circ Res vol. 114, (2) 242-248.

Dalli J, Norling LV, Montero-Melendez T, Federici Canova D, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al.(2014). Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis. EMBO Mol Med vol. 6, (1) 27-42.

Mathie SA, Bena S, Mondae M, Davda D, O'Donnell VB, Perretti M, Lloyd CM (2013). Activation of annexin A1-FPR2 axis promotes resolution of house dust mite induced airway hyper-reactivity. IMMUNOLOGY. vol. 140, 82-83.

Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ, Perretti M(2013). Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A vol. 110, (45) 18232-18237.

Cash JL, Bena S, Headland SE, McArthur S, Brancaleone V, Perretti M(2013). Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep vol. 14, (11) 999-1007.

Brancaleone V, Flower RJ, Cirino G, Perretti M (2013). Annexin A1 (AnxA1) mediates hydrogen sulfide (H2S) effects in the control of inflammation. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 31, S21-S22.

Perretti M, D'Acquisto F, Flower RJ(2013). Annexin-A1 Peptide Ac2-26. Handbook of Biologically Active Peptides,

Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M(2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Mol Cell Proteomics vol. 12, (8) 2205-2219.

Godson C, Perretti M(2013). Novel pathways in the yin-yang of immunomodulation. CURRENT OPINION IN PHARMACOLOGY vol. 13, (4) 543-546.

Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S et al.(2013). A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood vol. 122, (4) 608-617.

Iqbal AJ, Cooper D, Vugler A, Gittens BR, Moore A, Perretti M(2013). Endogenous galectin-1 exerts tonic inhibition on experimental arthritis. J Immunol vol. 191, (1) 171-177.

Dalli J, Consalvo AP, Ray V, Di Filippo C, D'Amico M, Mehta N, Perretti M(2013). Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor. J Immunol vol. 190, (12) 6478-6487.

Norling LV, Perretti M(2013). The role of omega-3 derived resolvins in arthritis. Curr Opin Pharmacol vol. 13, (3) 476-481.

Nusrat A, Leoni G, Neumann P-A, Alam A, Lambeth D, Hilgarth R, Kusters D, Reutelingsperger C et al. (2013). Annexin 1 in microparticles promotes intestinal mucosal wound repair during inflammation. JOURNAL OF IMMUNOLOGY. vol. 190,

Fowkes RC, Moradi-Bidhendi N, Branceleone V, Zariwala MG, Brady D, Jessop DS, Perretti M, Renshaw D(2013). Annexin-A1 protein and its relationship to cortisol in human saliva. PSYCHONEUROENDOCRINOLOGY vol. 38, (5) 722-727.

Ortega-Gomez A, Perretti M, Soehnlein O(2013). Resolution of inflammation: an integrated view. EMBO MOLECULAR MEDICINE vol. 5, (5) 661-674.

Ryan SM, McMorrow J, Umerska A, Patel HB, Kornerup KN, Tajber L, Murphy EP, Perretti M et al.(2013). An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis. J Control Release vol. 167, (2) 120-129.

Patel HB, Bombardieri M, Pitzalis C, Perretti M (2013). Activation of Melanocortin Receptor 3 as a new strategy to control experimental and rheumatoid arthritis. FASEB JOURNAL. vol. 27,

Cooray SN, Clark A, Flower R, Perretti M (2013). Agonist-induced conformational change of the Formyl Peptide Receptors. FASEB JOURNAL. vol. 27,

Thompson D, Perretti M (2013). Differential Trafficking of the FPR2/ALX receptor in response to endogenous or synthetic ligands. FASEB JOURNAL. vol. 27,

Leoni G, Neumann P-A, Alam A, Hilgarth RS, Lambeth DJ, Kusters D, Reutelingsperger C, Perretti M et al. (2013). Epithelial wound repair: insights into the multifaceted roles of Annexin A1. FASEB JOURNAL. vol. 27,

Montero-Melendez T, Dalli J, Perretti M(2013). Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors. Cell Death Differ vol. 20, (4) 567-575.

Gittens B, Perretti M, Cooper D (2013). Investigating Novel Roles for Exogenous and Endogenous Galectin-3 in Controlling Vascular Inflammation. FASEB JOURNAL. vol. 27,

Martin K, Perretti M, Ahluwalia A (2013). Kinin B1 receptor regulates inflammatory cell recruitment during low laminar shear stress. FASEB JOURNAL. vol. 27,

Perretti M, Bena S, Brancaleone V, Flower RJ (2013). Modulation of the receptor ALX/FPR2 in vascular inflammation. FASEB JOURNAL. vol. 27,

Perretti M, Dalli J, Norling LV, Montero-Melendez T, Hinds C (2013). Neutrophil Microparticles are heterogenous in content and function. FASEB JOURNAL. vol. 27,

Headland SE, Dell'Accio F, Perretti M (2013). Neutrophil-Derived Microparticles as Novel Effectors in Joint Disease. FASEB JOURNAL. vol. 27,

Norling LV, Perretti M (2013). Omega-3 derived Resolvin D1 reduces the severity of inflammatory arthritis. FASEB JOURNAL. vol. 27,

Poliselli Farsky SH, Machado ID, Santin JR, Ferraz VP, Gil CD, Oliani SM, Perretti M (2013). Role of cytosolic glucocorticoid receptor and Annexin-A1 on neutrophil traffic from bone marrow into blood: SDF-1alpha/CXCR-4/CXCR-2 axis. FASEB JOURNAL. vol. 27,

Rhodes DH, Pini M, Castellanos KJ, Montero-Melendez T, Cooper D, Perretti M, Fantuzzi G(2013). Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function. Obesity (Silver Spring) vol. 21, (2) 310-319.

Leoni G, Alam A, Neumann P-A, Lambeth JD, Cheng G, McCoy J, Hilgarth RS, Kundu K et al.(2013). Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. JOURNAL OF CLINICAL INVESTIGATION vol. 123, (1) 443-454.

Kosicka A, Cunliffe AD, Mackenzie R, Zariwala MG, Perretti M, Flower RJ, Renshaw D(2013). Attenuation of plasma annexin A1 in human obesity. FASEB JOURNAL vol. 27, (1) 368-378.

Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M, Wheatley C(2013). Biphasic modulation of NOS expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: downstream regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 expression. Mediators Inflamm vol. 2013,

Schutters K, Kusters DHM, Chatrou MLL, Montero-Melendez T, Donners M, Deckers NM, Krysko DV, Vandenabeele P et al.(2013). Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells. Cell Death Differ vol. 20, (1) 49-56.

Norling LV, Perretti M(2013). Control of myeloid cell trafficking in resolution. J Innate Immun vol. 5, (4) 367-376.

Ahmed TJ, Montero-Melendez T, Perretti M, Pitzalis C(2013). Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides. Int J Inflam vol. 2013,

Montero-Meléndez T, Llor X, García-Planella E, Perretti M, Suárez A(2013). Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling. PLoS One vol. 8, (10)

Pang J, Rhodes DH, Pini M, Akasheh RT, Castellanos KJ, Cabay RJ, Cooper D, Perretti M et al.(2013). Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice. PLoS One vol. 8, (2)

Viiri LE, Full LE, Navin TJ, Begum S, Didangelos A, Astola N, Berge RK, Seppala I et al.(2013). Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY vol. 54, 65-72.

Al-Kashi A, Montero-Melendez T, Moradi-Bidhendi N, Gilligan JP, Mehta N, Perretti M(2013). The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis. PLoS One vol. 8, (2)

Patel HB, Kornerup KN, Sampaio ALF, D'Acquisto F, Seed MP, Girol AP, Gray M, Pitzalis C et al.(2012). The impact of endogenous annexin A1 on glucocorticoid control of inflammatory arthritis. Ann Rheum Dis vol. 71, (11) 1872-1880.

Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G, Lucattelli M(2012). Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY vol. 47, (3) 332-339.

Perretti M(2012). Editorial: to resolve or not to resolve: annexin A1 pushes resolution on track. J Leukoc Biol vol. 92, (2) 245-247.

Headland S, Perretti M (2012). Neutrophil microparticles as novel effectors of joint disease. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 93, A30-A30.

Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M(2012). Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol vol. 32, (8) 1970-1978.

Bena S, Brancaleone V, Wang JM, Perretti M, Flower RJ(2012). Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling. J Biol Chem vol. 287, (29) 24690-24697.

Kabouridis PS, Pimentel TA, Brancaleone V, D'Acquisto F, Oliani SM, Perretti M, Jury EC(2012). Distinct localization of T cell Agrin during antigen presentation--evidence for the expression of Agrin receptor(s) in antigen-presenting cells. FEBS J vol. 279, (13) 2368-2380.

Vong L, Ferraz JGP, Dufton N, Panaccione R, Beck PL, Sherman PM, Perretti M, Wallace JL(2012). Up-Regulation of Annexin-A1 and Lipoxin A(4) in Individuals with Ulcerative Colitis May Promote Mucosal Homeostasis. PLOS ONE vol. 7, (6) Article ARTN e39244,

Clark AK, Grist J, Al-Kashi A, Perretti M, Malcangio M(2012). Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model. ARTHRITIS AND RHEUMATISM vol. 64, (6) 2038-2047.

Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D et al.(2012). The peritoneal tumour microenvironment of high-grade serous ovarian cancer. J Pathol vol. 227, (2) 136-145.

Liverani E, Banerjee S, Roberts W, Naseem KM, Perretti M(2012). Prednisolone exerts exquisite inhibitory properties on platelet functions. Biochem Pharmacol vol. 83, (10) 1364-1373.

Patel HB, Kornerup KN, Sampaio ALFS, D'Acquisto F, Seed MP, Girol AP, Gray M, Pitzalis C et al.(2012). The impact of endogenous annexin A1 on glucocorticoid control of inflammatory arthritis. Annals of the Rheumatic Diseases

Headland SE, Perretti M (2012). NEUTROPHIL MICROPARTICLES AS POTENTIAL NOVEL EFFECTORS OF JOINT DISEASE. RHEUMATOLOGY. vol. 51, 47-47.

Norling L, Dalli J, Flower R, Serhan C, Perretti M (2012). RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS. RHEUMATOLOGY. vol. 51, 47-48.

Cooper D, Iqbal AJ, Gittens BR, Cervone C, Perretti M(2012). The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?. Ann N Y Acad Sci vol. 1253, 181-192.

Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD et al.(2012). Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. FASEB J vol. 26, (3) 1064-1076.

Di Filippo C, Perretti M, Rossi F, Ferraraccio F, Motterlini R, D'Amico M(2012). Acute myocardial infarction in streptozotocin-induced hyperglycaemic rats: protection by a carbon monoxide-releasing molecule (CORM-3). NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY vol. 385, (2) 137-144.

de Lima CB, Tamura EK, Montero-Melendez T, Palermo-Neto J, Perretti M, Markus RP, Farsky SHP(2012). Actions of translocator protein ligands on neutrophil adhesion and motility induced by G-protein coupled receptor signaling. Biochem Biophys Res Commun vol. 417, (2) 918-923.

Dalli J, Montero-Melendez T, McArthur S, Perretti M(2012). Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol vol. 3,

Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M, Rankin SM(2012). Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow. FASEB J vol. 26, (1) 387-396.

Vincent TL, Williams RO, Maciewicz R, Silman A, Garside P, Bevan S, Chanalaris A, Chapman V et al.(2012). Mapping pathogenesis of arthritis through small animal models. Rheumatology (United Kingdom) vol. 51, (11) 1931-1941.

Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed M, Perretti M, Chernajovsky Y(2012). Molecular engineering of short half-life small peptides (VIP, αMSH and γ₃MSH) fused to latency-associated peptide results in improved anti-inflammatory therapeutics. Ann Rheum Dis vol. 71, (1) 143-149.

Greco KV, Iqbal AJ, Rattazzi L, Nalesso G, Moradi-Bidhendi N, Moore AR, Goldring MB, Dell'Accio F et al.(2011). High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents. Biochem Pharmacol vol. 82, (12) 1919-1929.

Nadkarni S, Cooper D, Brancaleone V, Bena S, Perretti M(2011). Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes. Arterioscler Thromb Vasc Biol vol. 31, (11) 2749-2759.

Damazo AS, Sampaio AL, Nakata CM, Flower RJ, Perretti M, Oliani SM(2011). Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis. BMC Immunol vol. 12,

Nadkarni S, Hollywood J, Mason JC, Dasgupta B, Perretti M (2011). Annexin-A1: A Potential Novel Biomarker in Giant Cell Arteritis. ARTHRITIS AND RHEUMATISM. vol. 63, S593-S593.

Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Frontiers in Immunology vol. 2, Article 41, 1-6.

Montero-Melendez T, Patel HB, Seed M, Nielsen S, Jonassen TEN, Perretti M(2011). The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties. Am J Pathol vol. 179, (1) 259-269.

Greco KV, Moore A, Dell'Accio F, Perretti M (2011). 3D CULTURES OF C-28/I2 CHONDROCYTES TO STUDY CHONDROCYTE BIOLOGY AND THERAPEUTIC DEVELOPMENT. INFLAMMATION RESEARCH. vol. 60, 283-283.

Brancaleone V, Sampaio AL, Cirino G, Flower RJ, Perretti M (2011). A NOVEL CROSS-TALK IN RESOLUTION: H2S ACTIVATES THE ANNEXIN A1 PATHWAY. INFLAMMATION RESEARCH. vol. 60, 49-49.

Iqbal AJ, Cooper D, Vugler AD, Moore A, Perretti M (2011). ENDOGENOUS GALECTIN-1 INHIBITS EXPERIMENTAL ARTHRITIS: A POTENTIAL SWEET THERAPEUTIC TARGET?. INFLAMMATION RESEARCH. vol. 60, 186-187.

Rhodes D, Pini M, Montero-Melendez T, Perretti M, Fantuzzi G (2011). EXPRESSION OF ANNEXIN A1 IN ADIPOSE TISSUE IS DISSOCIATED FROM MACROPHAGE INFILTRATION DURING DEVELOPMENT OF OBESITY IN MICE. INFLAMMATION RESEARCH. vol. 60, 261-261.

Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M (2011). GALECTIN-9: SWEETENING LEUKOCYTE RECRUITMENT. INFLAMMATION RESEARCH. vol. 60, 87-88.

Perretti M (2011). GLUCOCORTICOIDS CUT SHORT THE CONCERT OF INFLAMMATION THROUGH THE RELEASE OF ANNEXIN A1. INFLAMMATION RESEARCH. vol. 60, 16-17.

Montero-Melendez T, Jonassen T, Seed M, Perretti M (2011). MC3 AGONISTS AS NOVEL PRO-RESOLVING THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 269-269.

Greco KV, Montero-Melendez T, Patel H, Perretti M (2011). MELANOCORTIN RECEPTOR AGONISTS ARE NOVEL CHONDROPROTECTIVE THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 273-273.

Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed MP, Perretti M, Chernajovsky Y (2011). MOLECULAR ENGINEERING OF SHORT HALF LIFE SMALL PEPTIDES (VIP, alpha MSH AND gamma 3MSH) INTO LATENT ASSOCIATED PEPTIDE (LAP) RESULTS IN TARGETED ANTI-INFLAMMATORY AND ANTI-RHEUMATIC THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 43-43.

Norling LV, Dalli J, Serhan CN, Perretti M (2011). RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS. INFLAMMATION RESEARCH. vol. 60, 60-60.

Roviezzo F, Brancaleone V, De Gruttola L, Vellecco V, Bucci M, D'Agostino B, Cooper D, Sorrentino R et al.(2011). Sphingosine-1-phosphate modulates vascular permeability and cell recruitment in acute inflammation in vivo. J Pharmacol Exp Ther vol. 337, (3) 830-837.

Maione F, Cicala C, Liverani E, Mascolo N, Perretti M, D'Acquisto F(2011). IL-17A increases ADP-induced platelet aggregation. Biochem Biophys Res Commun vol. 408, (4) 658-662.

Norling LV, Spite M, Yang R, Flower RJ, Perretti M, Serhan CN(2011). Cutting Edge: Humanized Nano-Proresolving Medicines Mimic Inflammation-Resolution and Enhance Wound Healing. J IMMUNOL vol. 186, (10) 5543-5547.

Norling LV, Spite M, Yang R, Flower RJ, Perretti M, Serhan CN(2011). Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. Journal of Immunology vol. 186, (10) 5543-5547.

Velmurugan S, Kapil V, McKnight AHO, Aboud Z, Davies S, Milsom AB, Pearl V, Liverani E et al. (2011). Dietary nitrate attenuates platelet reactivity: Role of the erythrocyte and influence of sex. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 24, S35-S36.

Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ et al.(2011). Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol vol. 31, (5) 1075-1083.

Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G, Perretti M(2011). Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature. J Immunol vol. 186, (8) 4905-4914.

Montero-Melendez T, Patel HB, Perretti M(2011). Role of melanocortin receptors in the regulation of gouty inflammation. Curr Rheumatol Rep vol. 13, (2) 138-145.

Iqbal AJ, Sampaio ALF, Maione F, Greco KV, Niki T, Hirashima M, Perretti M, Cooper D(2011). Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect. Am J Pathol vol. 178, (3) 1201-1209.

Gavins FNE, Li G, Russell J, Perretti M, Granger DN(2011). Microvascular thrombosis and CD40/CD40L signaling. J Thromb Haemost vol. 9, (3) 574-581.

Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al.(2011). Anti-inflammatory role of the murine formyl-peptide receptor 2: Ligand-specific effects on leukocyte responses and experimental in-flammation (The Journal of Immunology (2010) 184, (2611-2619)). Journal of Immunology vol. 186, (4) 2684-2685.

Allegra M, D'Acquisto F, Tesoriere L, Livrea MA, Perretti M(2011). Cross-talk between minimally primed HL-60 cells and resting HUVEC reveals a crucial role for adhesion over extracellularly released oxidants. BIOCHEM PHARMACOL vol. 81, (3) 396-401.

Colucci M, Mastriota M, Maione F, Di Giannuario A, Mascolo N, Palmery M, Severini C, Perretti M et al.(2011). Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids. PEPTIDES vol. 32, (2) 266-271.

Pimentel TA, Sampaio ALF, D'Acquisto F, Perretti M, Oliani SM(2011). An essential role for mast cells as modulators of neutrophils influx in collagen-induced arthritis in the mouse. Lab Invest vol. 91, (1) 33-42.

Ryan SM, Patel HB, Kornerup KN, Tajber L, Umerska A, Perretti M, Brayden DJ (2011). Intra-articular delivery of salmon calcitonin nanocomplexes to the K/BXN murine model for treatment of osteoarthritis. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.

Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Front Immunol vol. 2,

Maione F, Paschalidis N, Iqbal AJ, Crompton T, Perretti M, D'Acquisto F(2010). Analysis of the inflammatory response in HY-TCR transgenic mice highlights the pathogenic potential of CD4- CD8- T cells. Autoimmunity vol. 43, (8) 672-681.

Patel HB, Bombardieri M, Sampaio ALF, D'Acquisto F, Gray M, Grieco P, Getting SJ, Pitzalis C et al.(2010). Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis. FASEB J vol. 24, (12) 4835-4843.

Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M(2010). Human RCAN3 gene expression and cell growth in endothelial cells. INT J MOL MED vol. 26, (6) 913-918.

Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M(2010). Human RCAN3 gene expression and cell growth in endothelial cells. Int J Mol Med vol. 26, (6) 913-918.

Nadkarni S, Brancaleone V, Bena S, Perretti M (2010). Protective effect of oestrogen is mediated by the anti-inflammatory protein annexin-A1. IMMUNOLOGY. vol. 131, 165-166.

Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F(2010). Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature. Blood vol. 116, (20) 4288-4296.

Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, Godson C(2010). FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. FASEB J vol. 24, (11) 4240-4249.

Perretti M, Dalli J, Bolla M, Padron J (2010). THE CINOD NCX 429 INHIBITS MICROVASCULAR INFLAMMATION THROUGH ITS NO-RELEASING PROPERTIES. OSTEOARTHRITIS AND CARTILAGE. vol. 18, S251-S251.

Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M(2010). Downstream gene activation of the receptor ALX by the agonist annexin A1. PLoS One vol. 5, (9)

Yazid S, Leoni G, Getting SJ, Cooper D, Solito E, Perretti M, Flower RJ(2010). Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol vol. 30, (9) 1718-1724.

Dufton N, Perretti M(2010). Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists. Pharmacol Ther vol. 127, (2) 175-188.

Dalli J, Rosignoli G, Hayhoe RPG, Edelman A, Perretti M(2010). CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway. AM J PATHOL vol. 177, (1) 176-186.

Sampaio ALF, Zahn G, Leoni G, Vossmeyer D, Christner C, Marshall JF, Perretti M(2010). Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis. J Leukoc Biol vol. 87, (5) 877-884.

Leoni G, Voisin M-B, Carlson K, Getting S, Nourshargh S, Perretti M(2010). The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature. Br J Pharmacol vol. 160, (1) 171-180.

Semple F, Webb S, Li HN, Patel HB, Perretti M, Jackson IJ, Gray M, Davidson DJ et al.(2010). Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo. EUR J IMMUNOL vol. 40, (4) 1073-1078.

Pederzoli-Ribeil M, Maione F, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F (2010). "Super" Annexin-A1: a novel tool to regulate neutrophil-driven inflammation?. EUR J CLIN INVEST. vol. 40, 47-47.

Dalli J, Cavalcanti DM, Farksy SH, Rankin S, Flower RJ, Perretti M (2010). Abnormalities in annexin a1 null bone marrow cells: evidence for failure of clearance of apoptotic neutrophils. EUR J CLIN INVEST. vol. 40, 49-49.

Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al.(2010). Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation. J Immunol vol. 184, (5) 2611-2619.

Sarndahl E, Bergstrom I, Nijm J, Forslund T, Perretti M, Jonasson L(2010). Enhanced neutrophil expression of annexin-1 in coronary artery disease. METABOLISM vol. 59, (3) 433-440.

Brancaleone V, Dalli J, Perretti M (2010). Mobilization of Annexin A1 in human polymorphonuclear leukocytes (PMN). EUR J CLIN INVEST. vol. 40, 36-37.

Paschalidis N, Huggins A, Rowbotham NJ, Furmanski AL, Crompton T, Flower RJ, Perretti M, D'Acquisto F(2010). Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection. CELL CYCLE vol. 9, (4) 785-794.

Spurr L, Nadkarni S, Pederzoli-Ribeil M, Goulding NJ, Perretti M, D'Acquisto F(2010). Comparative analysis of Annexin A1-Formyl Peptide Receptor 2/ALX expression in human leukocyte subsets. International Immunopharmacology vol. 11, (1) 55-66.

Patel HB, Leoni G, Melendez TM, Sampaio ALF, Perretti M(2010). Melanocortin Control of Cell Trafficking in Vascular Inflammation. vol. 681,

Cooper D, Ilarregui JM, Pesoa SA, Croci DO, Perretti M, Rabinovich GA(2010). Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate. vol. 480,

Hunter C, Kadakia TB, Cooper D, Perretti M, Schwartz RC, Brown SB(2010). Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands. THESCIENTIFICWORLDJOURNAL vol. 10, 1580-1596.

Di Filippo C, Monopoli A, Ongini E, Perretti M, D'Amico M(2010). The Cardio-Protective Properties of Ncx-6550, a Nitric Oxide Donating Pravastatin, in the Mouse. MICROCIRCULATION vol. 17, (6) 417-426.

Paschalidis N, Iqbal AJ, Maione F, Wood EG, Perretti M, Flower RJ, D'Acquisto F(2009). Modulation of experimental autoimmune encephalomyelitis by endogenous annexin A1. J Neuroinflammation vol. 6,

Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P et al.(2009). Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis. Arterioscler Thromb Vasc Biol vol. 29, (11) 1757-1763.

Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M et al.(2009). Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. NATURE vol. 461, (7268) 1287-U125.

Perretti M, Dalli J(2009). Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics. Br J Pharmacol vol. 158, (4) 936-946.

McColl A, Bournazos S, Franz S, Perretti M, Morgan BP, Haslett C, Dransfield I(2009). Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages. J IMMUNOL vol. 183, (3) 2167-2175.

Piqueras L, Sanz MJ, Perretti M, Morcillo E, Norling L, Mitchell JA, Li Y, Bishop-Bailey D(2009). Activation of PPAR beta/delta inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release. J LEUKOCYTE BIOL vol. 86, (1) 115-122.

Pederzoli-Ribeil M, Maione F, Perretti M, D'Acquisto F (2009). Annexin-A1, a novel pathway effector of neutrophil behavior in Wegener disease?. APMIS. vol. 117, 118-118.

Norling LV, Perretti M, Cooper D(2009). Endogenous galectins and the control of the host inflammatory response. J Endocrinol vol. 201, (2) 169-184.

Sampaio ALF, Leoni G, Marshall JF, Perretti M (2009). A role for alpha 5 beta 1 integrin in leukocyte accumulation in acute peritonitis. EUR J CLIN INVEST. vol. 39, 22-23.

Patel HB, Bombardieri M, Pitzalis C, Perretti M(2009). Activation of melanocortin receptor type 3 as a new strategy to control experimental and rheumatoid arthritis. EUR J CLIN INVEST vol. 39, 29-29.

Huggins A, Paschalidis N, Flower RJ, Perretti M, D'Acquisto F(2009). Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J vol. 23, (4) 985-996.

Pederzoli-Ribeil M, Maione F, Perretti M, D'Acquisto F(2009). The impact of Annexin-A1 cleavage on neutrophil behaviour during vascular inflammation. EUR J CLIN INVEST vol. 39, 37-37.

Perretti M, Dufton N, Patel HB, Hannon R, Flower RJ (2009). The role of ALX/FPRL-1 in inflammation and its impact on Annexin A1 biology. EUR J CLIN INVEST. vol. 39, 24-24.

Tripatara P, Patel NSA, Brancaleone V, Renshaw D, Rocha J, Sepodes B, Mota-Filipe H, Perretti M et al.(2009). Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. Eur J Pharmacol vol. 606, (1-3) 205-209.

Maione F, Paschalidis N, Mascolo N, Dufton N, Perretti M, D'Acquisto F(2009). Interleukin 17 sustains rather than induces inflammation. Biochem Pharmacol vol. 77, (5) 878-887.

Hecht I, Rong J, Sampaio ALF, Hermesh C, Rutledge C, Shemesh R, Toporik A, Beiman M et al.(2009). A Novel Peptide Agonist of Formyl-Peptide Receptor-Like 1 (ALX) Displays Anti-Inflammatory and Cardioprotective Effects. J PHARMACOL EXP THER vol. 328, (2) 426-434.

Perretti M, D'Acquisto F(2009). Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol vol. 9, (1) 62-70.

Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M, Oliani SM(2009). Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation. AM J PATHOL vol. 174, (1) 177-183.

Dufton NP, Hannon R, Perretti M, Flower R(2009). Quantitative Analysis of Promoter Activity by Green Fluorescent Protein (GFP) Target/Reporter Strategy in a Novel Transgenic alx/fpr-rs2 Null Mouse. Inflammation Research vol. 58, (2) S252-S255.

Getting SJ, Riffo-Vasquez Y, Pitchford S, Kaneva M, Grieco P, Page CP, Perretti M, Spina D(2008). A role for MC3R in modulating lung inflammation. PULM PHARMACOL THER vol. 21, (6) 866-873.

Leoni G, Patel HB, Sampaio ALF, Gavins FNE, Murray JF, Grieco P, Getting SJ, Perretti M(2008). Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion. FASEB J vol. 22, (12) 4228-4238.

Babbin BA, Laukoetter MG, Nava P, Koch S, Lee WY, Capaldo CT, Peatman E, Severson EA et al.(2008). Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. J IMMUNOL vol. 181, (7) 5035-5044.

Oliani SM, Ciocca GAP, Pimentel TA, Damazo AS, Gibbs L, Perretti M(2008). Fluctuation of annexin-A1 positive mast cells in chronic granulomatous inflammation. INFLAMM RES vol. 57, (10) 450-456.

Dalli J, Norling LV, Renshaw D, Cooper D, Leung KY, Perretti M(2008). Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles. BLOOD vol. 112, (6) 2512-2519.

D'Acquisto F, Perretti M, Flower RJ(2008). Annexin-A1: a pivotal regulator of the innate and adaptive immune systems. BRIT J PHARMACOL vol. 155, (2) 152-169.

D'Acquisto F, Perretti M(2008). Overview of the role of annexin 1 in the innate and adaptive immune response. Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry vol. 8, (3) 252-258.

Dufton N, Buckingham J, Perretti M, Flower R(2008). Initial characterisation of the novel transgenic, the alx/fpr-rs2 null mouse. FUND CLIN PHARMACOL vol. 22, 48-48.

Cooper D, Norling LV, Perretti M(2008). Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow. J LEUKOCYTE BIOL vol. 83, (6) 1459-1466.

Sarndahl E, Bergstrom I, Nijm J, Perretti M, Jonasson L(2008). ENHANCED NEUTROPHIL EXPRESSION OF ANNEXIN-1 IN CORONARY ARTERY DISEASE. ATHEROSCLEROSIS SUPP vol. 9, (1) 15-15.

D'Acquisto F, Paschalidis N, Raza K, Buckley CD, Flower RJ, Perretti M(2008). Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells. Rheumatology (Oxford) vol. 47, (5) 636-639.

Dasgupta B, Dalli J, Norling L, Pederzoli-Ribeil M, Hollywood J, D'Acquisto F, Perretti M (2008). Altered expression of annexin 1 and its receptor in neutrophils of patients with giant cell arteritis (GCA) and ANCA associated vasculitis (AAV). RHEUMATOLOGY. vol. 47, II99-II99.

Martin GR, Perretti M, Flower RJ, Wallace JL(2008). Annexin-1 modulates repair of gastric mucosal injury. AM J PHYSIOL-GASTR L vol. 294, (3) G764-G769.

Norling LV, Sampaio ALF, Cooper D, Perretti M(2008). Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking. FASEB J vol. 22, (3) 682-690.

Yona S, Lin HH, Dri P, Davies JQ, Hayhoe RPG, Lewis SM, Heinsbroek SEM, Brown KA et al.(2008). Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function. FASEB J vol. 22, (3) 741-751.

Finney SJ, Anning PB, Cao TV, Perretti M, Evans TW, Burke-Gaffney A(2007). Butanol-extracted lipoteichoic acid induces in vivo leukocyte adhesion. BIOCHEM BIOPH RES CO vol. 364, (4) 831-837.

O'Sullivan TP, Vallin KSA, Shah STA, Fakhry J, Maderna P, Scannell M, Sampaio ALF, Perretti M et al.(2007). Aromatic lipoxin A(4) and lipoxin B-4 analogues display potent biological activities. J MED CHEM vol. 50, (24) 5894-5902.

D'Acquisto F, Paschalidis N, Sampaio ALF, Merghani A, Flower RJ, Perretti M(2007). Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells. EUR J IMMUNOL vol. 37, (11) 3131-3142.

Vong L, D'Acquisto F, Pederzoli-Ribeil M, Lavagno L, Flower RJ, Witko-Sarsat R, Perretti M(2007). Annexin 1 cleavage in activated neutrophils - A pivotal role for proteinase 3. J BIOL CHEM vol. 282, (41) 29998-30004.

Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M, Ahluwalia A(2007). A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5. J Immunol vol. 179, (7) 4849-4856.

Perretti M, Mancini L(2007). Potential of calcitonin as a novel cotreatment for arthritis. Future Rheumatology vol. 2, (5) 493-496.

Gavins FNE, Dalli J, Flower RJ, Granger DN, Perretti M(2007). Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation. FASEB J vol. 21, (8) 1751-1758.

Piqueras L, Norlyng L, Perretti M, Li Y, Sanz MJ, Real JT, Warner T, Bishop-Bayley D (2007). PPARb inhibits neutrophil-endothelium interactions under flow. INFLAMM RES. vol. 56, S453-S454.

Urquhart P, Rosignoli G, Cooper D, Motterlini R, Perretti M(2007). Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow. J Pharmacol Exp Ther vol. 321, (2) 656-662.

John CD, Sahni V, Mehet D, Morris JF, Christian HC, Perretti M, Flower RJ, Solito E et al.(2007). Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides. FASEB J vol. 21, (4) 1037-1046.

Giner RM, Mancini L, Kamal AM, Perretti M(2007). Uneven modulation of the annexin 1 system in osteoblast-like cells by dexamethasone. BIOCHEM BIOPH RES CO vol. 354, (2) 414-419.

Mancini L, Paul-Clark MJ, Rosignoli G, Hannon R, Martin JE, Macintyre I, Perretti M(2007). Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis. AM J PATHOL vol. 170, (3) 1018-1027.

D'Acquisto F, Merghani A, Lecona E, Rosignoli G, Raza K, Buckley CD, Flower RJ, Perretti M(2007). Annexin-1 modulates T-cell activation and differentiation. Blood vol. 109, (3) 1095-1102.

Perretti M(2007). Glucocorticoids in innate immunity: more transactivation than transrepression!. BLOOD vol. 109, (3) 852-853.

Serhan CN, Brain SD, Buckley CD, Gilroy DW, Haslett C, O'Neill LAJ, Perretti M, Rossi AG et al.(2007). Resolution of inflammation: state of the art, definitions and terms. FASEB J vol. 21, (2) 325-332.

Getting SJ, Lam CW, Leoni G, Gavins FNE, Grieco P, Perretti M(2006). [D-Trp(8)]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse). MOL PHARMACOL vol. 70, (6) 1850-1855.

Sawmynaden P, Perretti M(2006). Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes. Biochem Biophys Res Commun vol. 349, (4) 1351-1355.

Getting SJ, Lam CW, Chen AS, Grieco P, Perretti M(2006). Melanocortin 3 receptors control crystal-induced inflammation. FASEB J vol. 20, (13) 2234-2241.

Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ, Solito E, Perretti M(2006). Antiflammin-2 activates the human formyl-peptide receptor like 1. ScientificWorldJournal vol. 6, 1375-1384.

Flower RJ, Ayoub S, Perretti M(2006). Anti-inflammatory and analgesic aspects of the annexin A1 system. ACTA PHARMACOL SIN vol. 27, (9) 1272-1272.

Cassatella MA, Perretti M(2006). Immunomodulation. The promises of immunopharmacology for the development of new drugs. Current Opinion in Pharmacology vol. 6, (4) 376-378.

Flower RJ, Perretti M, D'Acquisto F, Buckingham JC(2006). Annexin 1, anti-inflammatory drugs and the neuroendocrine-immune interface. ACTA PHARMACOL SIN vol. 27, 13-14.

Yona S, Heinsbroek SEM, Peiser L, Gordon S, Perretti M, Flower RJ(2006). Impaired phagocytic mechanism in annexin 1 null macrophages. BRIT J PHARMACOL vol. 148, (4) 469-477.

Gil CD, La M, Perretti M, Oliani SM(2006). Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3. CELL BIOL INT vol. 30, (4) 338-344.

Perretti M, D'Acquisto F(2006). Novel aspects of annexin 1 and glucocorticoid biology: intersection with nitric oxide and the lipoxin receptor. Inflamm Allergy Drug Targets vol. 5, (2) 107-114.

Damazo AS, Yona S, Flower RJ, Perretti M, Oliani SM(2006). Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis. J IMMUNOL vol. 176, (7) 4410-4418.

D'Acquisto F, Merghani A, Lecona E, Guglielmo R, Vo P, Raza K, Buckley C, Flower RJ et al. (2006). Annexin A1: a novel target of the immunosuppressive effects of glucocorticoids in autoimmune diseases. FASEB JOURNAL. vol. 20, A1376-A1376.

Babbin BA, Lee W, Winfree LM, Akyildiz A, Parkos CA, Perretti M, Nusrat A (2006). Annexin I regulates epithelial cell migration by signaling through formyl peptide receptors. FASEB JOURNAL. vol. 20, A1093-A1093.

Urquhart P, Cooper D, Motterlini R, Perretti M (2006). CO-releasing molecules modulate leukocyte/endothelial cell adhesion: under static and flow studies. FASEB JOURNAL. vol. 20, A1321-A1321.

Vong L, D'Acquisto F, Flower RJ, Witko-Sarsat V, Perretti M (2006). Cleavage of Annexin-A1 by proteinase 3: a possible cause of Wegener's vasculitis?. FASEB JOURNAL. vol. 20, A645-A645.

Renshaw D, Dalli J, Kamal A, Perretti M (2006). Disinct patterns of gene expression induced by annexin 1 activation of the ALXR receptor in HEK293 cells. FASEB JOURNAL. vol. 20, A646-A646.

Norling LV, Cooper D, Perretti M (2006). Endogenous Galectn-1 inhibits lymphocyte-endothelial cell interactions as determined by small interference RNA. FASEB JOURNAL. vol. 20, A647-A647.

Renshaw D, Sawmynadan P, Dalli J, Perretti M (2006). Glucocorticoid regulated expression of the anti-inflammatory receptor ALXR. FASEB JOURNAL. Conference: Experimental Biology 2006 Meeting (San Francisco, CA) from: 01/04/2006 to: 05/04/2006, vol. 20, A645-A645.

Duchene J, Lecomte F, Perretti M, Ahluwalia A (2006). Inflammatory chemokine CXCL5 expression by endothelial cells is dependent upon kinin B1 receptor activation. FASEB JOURNAL. vol. 20, A702-A702.

Hayhoe RPG, Cooper D, Perretti M (2006). The anti-adhesive effects of Annexin 1 on neutrophil-endothelial interactions under flow. FASEB JOURNAL. vol. 20, A646-A646.

Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D, Perretti M(2006). Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. BLOOD vol. 107, (5) 2123-2130.

Getting SJ, Di Filippo C, D'Amico M, Perretti M(2006). The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage. EUR J PHARMACOL vol. 532, (1-2) 138-144.

Lam CW, Perretti M, Getting SJ(2006). Melanocortin receptor signaling in RAW264.7 macrophage cell line. Peptides vol. 27, (2) 404-412.

Perretti M, GETTING SJ, Spina D, Riffo-Vasquez Y, Page C, Pitchford S, Grieco P (2006). A role for MC3R in modulating eosinophil migration in allergic inflammation. Am J Pathol.

PERRETTI M, Nusrat A, Akyildiz A, Parkos CA, Babbin BA, Lee WY, Winfree LM(2006). Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors. J Biol Chem vol. 281, 19588-19599.

Allegra M, Tesoriere L, D'acquisto F, Perretti M, Livrea M (2006). Indicaxanthin and betanin suppress LPS-induced NF-kappa B activation and modulate the levels of inflammatory mediators iNOS, COX-2 and PGE2 in macrophages. FREE RADICAL RESEARCH. vol. 40, S113-S113.

Perretti M, COOPER D, Gil CD, Oliani SM, Rosignoli G(2006). Inflammation-induced modulation of cellular galectin-1 and –3 expression in a model of rat peritonitis. inflammation Research vol. 55, (3) 99-107.

Renshaw D, Urquhart P, Perretti M(2006). Therapeutic exploitation of endogenous anti-inflammatory mechanisms: Old and new leads. Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry vol. 5, (4) 289-305.

Moraes LA, Paul-Clark MJ, Rickman A, Flower RJ, Goulding NJ, Perretti M(2005). Ligand-specific glucocorticoid receptor activation in human platelets. Blood vol. 106, (13) 4167-4175.

Bensalem N, Ventura AP, Vallee B, Lipecka J, Tondelier D, Davezac N, Dos Santos A, Perretti M et al.(2005). Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients. MOL CELL PROTEOMICS vol. 4, (10) 1591-1601.

Gavins FNE, Sawmynaden P, Chatterjee BE, Perretti M(2005). A twist in anti-inflammation: annexin 1 acts via the lipoxin A4 receptor. Prostaglandins Leukot Essent Fatty Acids vol. 73, (3-4) 211-219.

Chatterjee BE, Yona S, Rosignoli G, Young RE, Nourshargh S, Flower RJ, Perretti M(2005). Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro. J Leukoc Biol vol. 78, (3) 639-646.

MacIntyre I, Mancini L, Perretti M (2005). Calcitonin abolishes collagen-induced arthritis. JOURNAL OF BONE AND MINERAL RESEARCH. vol. 20, S198-S199.

Yona S, Heinsbroek S, Gordon S, Perretti M, Flower RJ(2005). A novel role for Annexin 1 in macrophage phagocytosis. INFLAMM RES vol. 54, S217-S218.

Gavins FN, Granger N, Perretti M (2005). Annexin 1 Peptide Protects against Focal Cerebral Ischaemia-Reperfusion Injury in Mice. INFLAMM RES. vol. 54, S167-S167.

Gilroy DW, Perretti M(2005). Aspirin and steroids: new mechanistic findings and avenues for drug discovery. CURR OPIN PHARMACOL vol. 5, (4) 405-411.

Marchand F, Perretti M, McMahon SB(2005). Role of the immune system in chronic pain. NAT REV NEUROSCI vol. 6, (7) 521-532.

Damazo AS, Yona S, D'Acquisto F, Flower RJ, Oliani SM, Perretti M(2005). Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation. AM J PATHOL vol. 166, (6) 1607-1617.

Maderna P, Yona S, Perretti M, Godson C(2005). Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide AC(2-26). J IMMUNOL vol. 174, (6) 3727-3733.

Duchene J, Perretti M, Ahluwalia A (2005). Chemokine involvement in kinin B1 receptor-mediated leukocyte recruitment. FASEB JOURNAL. vol. 19, A1512-A1513.

Flower RJ, Perretti M(2005). Controlling inflammation: a fat chance?. J Exp Med vol. 201, (5) 671-674.

Perretti M, Damazo AS, Yona S, D'acquisto F, Oliani SM, Flower RJ (2005). Critical protective role for annexin 1 gene expression in mouse endotoxemia. FASEB JOURNAL. vol. 19, A1221-A1222.

Cooper D, Hayhoe RPG, Perretti M (2005). Effect of annexin 1 in an in vitro model of human neutrophil-endothelial interaction under flow. FASEB JOURNAL. vol. 19, A1522-A1522.

Cooper D, Perretti M (2005). Galectin-1 inhibits neutrophil rolling in a carbohydrate-dependent manner. FASEB JOURNAL. vol. 19, A1512-A1512.

Perretti M, Chatterjee BE, Yona S, Flower RJ (2005). Higher degree of neutrophil activation in vitro and within the microcirculation in absence of annexin 1 (Anx-A1) gene. FASEB JOURNAL. vol. 19, A1262-A1262.

Perretti M, Lam CW, Getting SJ (2005). In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation. FASEB JOURNAL. vol. 19, A1421-A1421.

Kamal AM, Sawmynaden P, Perretti M (2005). Interaction of annexin 1 (Anx-A1) and its bioactive peptides with receptors of the human FPR family. FASEB JOURNAL. vol. 19, A1513-A1513.

Perretti M, Mancini L, Paul-Clark MJ, Hannon R, Macintyre I (2005). Calcitonin (CT) and glucocorticoids (GC) have contrasting effects on the RANKL/OPG system in osteoblast-like cells. FASEB JOURNAL. vol. 19, A93-A93.

Perretti M, Gavins FNE, Kamal AM, D'Amico M, Oliani SM (2005). Formyl-peptide receptor is not involved in the protection afforded by annexin 1 in marine acute myocardial infarct. FASEB JOURNAL. vol. 19, A707-A707.

Perretti M, Lam CW, Getting SJ, Di Filippo C, D'Amico M (2005). MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct. FASEB JOURNAL. vol. 19, A485-A485.

Kamal AM, Flower RJ, Perretti M(2005). An overview of the effects of annexin 1 on cells involved in the inflammatory process. Mem Inst Oswaldo Cruz vol. 100 Suppl 1, 39-47.

Zanardo RCO, Perretti M, Wallace JL(2005). Annexin-1 is an endogenous gastroprotective factor against indomethacin-induced damage. AM J PHYSIOL-GASTR L vol. 288, (3) G481-G486.

Basoni C, Nobles M, Grimshaw A, Desgranges C, Davies D, Perretti M, Kramer IM, Genot E(2005). Inhibitory control of TGF-beta 1 on the activation of Rap1, CD11b, and transendothelial migration of leukocytes. FASEB J vol. 19, (3) 822-+.

Lam CW, Getting SJ, Perretti M(2005). In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation. J IMMUNOL vol. 174, (4) 2297-2304.

Yona S, Ward B, Buckingham JC, Perretti M, Flower RJ(2005). Macrophage biology in the Anx-A1-/- mouse. Prostaglandins Leukot Essent Fatty Acids vol. 72, (2) 95-103.

Flower RJ, PERRETTI M, Diaz BL, Bandeira-Melo C, Martins MA, Carvalho VF, Silva PM, Jose PJ et al.(2005). A novel effect for annexin 1-derived peptide ac2-26: reduction of allergic inflammation in the rat. J Pharmacol Exp Ther vol. 313, (3) 1416-1422.

Kamal AM, Flower RJ, Perretti M (2005). An overview of the effects of annexin 1 on cells involved in the inflammatory process. Memorias do Instituto Oswaldo Cruz. vol. 100, 39-48.

Gavins FNE, Kamal AM, D'Amico M, Oliani SM, Perretti M(2005). Formyl-peptide receptor is not involved in the protection afforded by annexin 1 in murine acute myocardial infarct. FASEB J vol. 19, (1) 100-102.

Alam CAS, Seed MP, Freemantle C, Brown J, Perretti M, Carrier M, Divwedi A, West DC et al.(2005). The inhibition of neutrophil-endothelial cell adhesion by hyaluronan independent of CD44. Inflammopharmacology vol. 12, (5-6) 535-550.

Smith T, Perretti M, Patton JT, Sarkar A, Magnani JL (2004). Pan-selectin glycomimetic inhibitors inhibit rolling and neutrophil migration in mouse models of inflammation. GLYCOBIOLOGY. vol. 14, 1202-1203.

Cao TV, La M, Getting SJ, Day AJ, Perretti M(2004). Inhibitory effects of TSG-6 link module on leukocyte-endothelial cell interactions in vitro and in vivo. MICROCIRCULATION vol. 11, (7) 615-624.

Getting SJ, Di Filippo C, Christian HC, Lam CW, Rossi F, D'Amico M, Perretti M(2004). MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct. J LEUKOCYTE BIOL vol. 76, (4) 845-853.

Di Filippo C, Rossi F, Ongini E, Del Soldato P, Perretti M, D'Amico M(2004). The distinct alterations produced in cardiovascular functions by prednisolone and nitro-prednisolone (NCX-1015) in the rat highlight a causal role for endothelin-1. J PHARMACOL EXP THER vol. 310, (3) 1133-1141.

Perretti M, Flower RJ(2004). Annexin 1 and the biology of the neutrophil. J Leukoc Biol vol. 76, (1) 25-29.

Yona S, Buckingham JC, Perretti M, Flower RJ(2004). Stimulus-specific defect in the phagocytic pathways of annexin 1 null macrophages. Br J Pharmacol vol. 142, (5) 890-898.

MARTIN JE, Flower RJ, Perretti M, Hannon R, Getting SJ, Gavins FNE, Christian HC, Parente L et al.(2004). The Annexin 1-/- Mouse: Phenotypic Studies. Annexins vol. 1, (2) 109-120.

Perretti M, Solito E(2004). Annexin 1 and neutrophil apoptosis. Biochem Soc Trans vol. 32, (Pt3) 507-510.

Gilroy DW, Lawrence T, Perretti M, Rossi AG(2004). Inflammatory resolution: new opportunities for drug discovery. Nat Rev Drug Discov vol. 3, (5) 401-416.

Pieretti S, Di Giannuario A, De Felice M, Perretti M, Cirino G(2004). Stimulus-dependent specificity for annexin 1 inhibition of the inflammatory nociceptive response: the involvement of the receptor for formylated peptides. PAIN vol. 109, (1-2) 52-63.

Young RE, Thompson RD, Larbi KY, La M, Roberts CE, Shapiro SD, Perretti M, Nourshargh S(2004). Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo. J IMMUNOL vol. 172, (7) 4493-4502.

Yang YH, Morand EF, Getting SJ, Paul-Clark M, Liu DL, Yona S, Hannon R, Buckingham JC et al.(2004). Modulation of inflammation and response to dexamethasone by annexin 1 in antigen-induced arthritis. ARTHRITIS RHEUM vol. 50, (3) 976-984.

Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S, Hobbs AJ(2004). Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. P NATL ACAD SCI USA vol. 101, (5) 1386-1391.

Baraldi PG, Romagnoli R, Nunez MD, Perretti M, Paul-Clark MJ, Ferrario M, Govoni M, Benedini F et al.(2004). Synthesis of nitro esters of prednisolone, new compounds combining pharmacological properties of both glucocorticoids and nitric oxide. J MED CHEM vol. 47, (3) 711-719.

Moraes LA, Giner RM, Paul-Clark MJ, Perretti M, Perrett D(2004). An isocratic HPLC method for the quantitation of eicosanoids in human platelets. BIOMED CHROMATOGR vol. 18, (1) 64-68.

PERRETTI M, Oliani SM, Takahashi HK, Damazo AS, Paul-Clark MJ, Straus AH(2004). Analysis of annexin 1 expression in rat trachea: study of mast cell heterogeneity. ANNEXINS vol. 1, 12-18.

Perretti M(2003). The annexin 1 receptor(s): is the plot unravelling?. TRENDS PHARMACOL SCI vol. 24, (11) 574-579.

La M, Cao TV, Cerchiaro G, Chilton K, Hirabayashi J, Kasao K, Oliani SM, Chernajovsky Y et al.(2003). A novel biological activity for galectin-1 - Inhibition of leukocyte-endothelial cell interactions in experimental inflammation. AM J PATHOL vol. 163, (4) 1505-1515.

Paul-Clark MJ, Roviezzo F, Flower RJ, Cirino G, Del Soldato P, Adcock IM, Perretti M(2003). Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands. J IMMUNOL vol. 171, (6) 3245-3252.

Getting SJ, Schioth HB, Perretti M(2003). Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides. J PHARMACOL EXP THER vol. 306, (2) 631-637.

Paul-Clark MJ, Perretti M (2003). The enhanced anti-inflammatory properties of nitro-prednisolone (NCX-1015) is linked to post-translational modification of the glucocorticoid receptor. INFLAMMATION RESEARCH. vol. 52, S194-S196.

Solito E, Kamal A, Russo-Marie F, Buckingham JC, Marullo S, Perretti M(2003). A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils. FASEB J vol. 17, (9) 1544-+.

Gavins FNE, Yona S, Kamal AM, Flower RJ, Perretti M(2003). Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms. Blood vol. 101, (10) 4140-4147.

Perretti M, Paul-Clark MJ, Mancini L, Flower RJ(2003). Generation of innovative anti-inflammatory and anti-arthritic glucocorticoid derivatives that release NO: the nitro-steroids. DIGEST LIVER DIS vol. 35, S41-S48.

Gavins FNE, Gao JL, Murphy PM, Flower RJ, Perretti M (2003). An annexin 1 peptide reduces myocardial ischaemia reperfusion in the mouse. BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U9-U9.

Perretti M, Gavins FNE(2003). Annexin 1: an endogenous anti-inflammatory protein. News Physiol Sci vol. 18, 60-64.

Goulding NJ, Rickford AKB, Sherratt KM, Paul-Clark MJ, Flower RJ, Perretti M (2003). Characterisation of a novel glucocorticoid receptor inhuman platelets. BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U61-U61.

Paul-Clark MJ, Getting SJ, Roviezzo F, Del Soldato P, Flower RJ, Perretti M (2003). Effects of a novel NO-releasing glucocorticoid (NCX-1015) in a rat model of gout. BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U38-U38.

Solito E, Perretti M (2003). Exogenous annexin 1 promotes human neutrophil apoptosis. BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U7-U7.

Mancini L, Paul-Clark MJ, Hannon R, MacIntyre I, Perretti M (2003). Glucocorticoid modulation of RANKL and osteoprotegerin in osteoblast cell lines. BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U61-U61.

Getting SJ, Lam CW, Christian HC, Gavins FNE, Flower RJ, Schioth HB, Perretti M (2003). Melanocortin agonists possess anti-inflammatory effects in mice with a non-functional MC1-R (recessive yellow e/e). BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U6-U6.

Getting SJ, Di Filippo C, Lam CW, Rossi F, Flower RJ, D'Amico M, Perretti M (2003). Protective role of melanocortin type 3 receptor in myocardial ischaemia-reperfusion injury in mice. BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U72-U72.

Gavins FNE, Flower RJ, Perretti M (2003). A Boc-sensitive receptor, distinct from FPR, mediates the anti-inflammatory action of an annexin 1 peptide in the mouse heart. FASEB JOURNAL. vol. 17, A1074-A1074.

Paul-Clark MJ, Getting SJ, Flower RJ, Del Soldato P, Perretti M (2003). Anti-arthritic properties of an NO-donating glucocorticoid, NCX-1015. FASEB JOURNAL. vol. 17, A1061-A1061.

Foster P, Mathur A, McLean P, Perretti M, Moncada S, Ahluwalia A, Hobbs A (2003). Anti-leukocyte properties of a novel non NO-based soluble guanylate cyclase activator, BAY 41-2272. FASEB JOURNAL. vol. 17, A1052-A1052.

La M, Chilton K, Hirabayashi J, Kasai K, Chernajovsky Y, Perretti M (2003). Evidence for specific Galectin-1 binding proteins on human neutrophil. FASEB JOURNAL. vol. 17, A796-A796.

Oliani SM, Damazo AS, Paul-Clark MJ, Perretti M (2003). Mast cell heterogeneity: analysis of annexin 1 expression in rat trachea. FASEB JOURNAL. vol. 17, A1070-A1070.

Getting SJ, Lam CW, Christian HC, Flower RJ, Schioth H, Perretti M (2003). Melanocortin agonists possess anti-inflammatory effect in mice with a non-funetional MC1-R (recessive yellow e/e mice). FASEB JOURNAL. vol. 17, A1069-A1069.

Young RE, Thompson RD, Larbi KY, La M, Roberts C, Shapir SD, Perretti M, Nourshargh S (2003). Neutrophil elastase (NE) plays a non-redundant role in zymosan-induced leukocyte migration. FASEB JOURNAL. vol. 17, A1188-A1188.

Vo PA, Syed I, McLean P, Bascands JL, Perretti M, Ahluwalia A (2003). Regulation of kinin B1 receptors in emlothelial cells by laminar shear stress. FASEB JOURNAL. vol. 17, A1056-A1056.

Getting SJ, Christian HC, Lam CW, Gavins FNE, Flower RJ, Schioth HB, Perretti M(2003). Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: Studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. J IMMUNOL vol. 170, (6) 3323-3330.

Kamal AM, Giner RM, Paramasivam AM, Perretti M (2003). Annexin 1 interactions with receptors of the formylated peptide family. FASEB JOURNAL. vol. 17, A638-A638.

Hannon R, Croxtall JD, Getting SJ, Roviezzo F, Yona S, Paul-Clark MJ, Gavins FNE, Perretti M et al.(2003). Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J vol. 17, (2) 253-255.

PERRETTI M, Marullo S, Buckingham JC, Russo-Marie F, Solito E, Kamal A (2003). A novel calcium-dependent pro-apoptotic effect of annexin 1 on human neutrophils. FASEB J. vol. 17, 1544-1546.

PERRETTI M, Parente L(2003). Advances in the pathophysiology of constitutive and inducible cyclooxygenases: two enzymes in the spotlight. Biochemical Pharmacology vol. 65, (2) 153-159.

Perretti M, Getting SJ(2003). Migration of specific leukocyte subsets in response to cytokine or chemokine application in vivo. vol. 225,

Getting SJ, Mahoney DJ, Cao T, Rugg MS, Fries E, Milner CM, Perretti M, Day AJ(2002). The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner. J Biol Chem vol. 277, (52) 51068-51076.

Yona S, Perretti M, Buckingham JC, Morris JF, Flower RJ (2002). Altered degree of activation and steroid inhibition in leukocytes from annexin 1 null mice. BRITISH JOURNAL OF PHARMACOLOGY. vol. 137,

Roviezzo F, Getting SJ, Paul-Clark MJ, Yona S, Gavins FNE, Perretti M, Hannon R, Croxtall JD et al. (2002). The annexin-1 knockout mouse: What it tells us about the inflammatory response. Journal of Physiology and Pharmacology. vol. 53, 541-553.

Roviezzo F, Getting SJ, Paul-Clark MJ, Yona S, Gavins FNE, Perretti M, Hannon R, Croxtall JD et al. (2002). The annexin-1 knockout mouse: What it tells us about the inflammatory response. JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. vol. 53, 541-553.

Fiorucci S, Antonelli E, Distrutti E, Del Soldato P, Flower RJ, Clark MJP, Morelli A, Perretti M et al.(2002). NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. P NATL ACAD SCI USA vol. 99, (24) 15770-15775.

Perretti M, Chiang N, La M, Fierro IM, Marullo S, Getting SJ, Solito E, Serhan CN(2002). Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A(4) receptor. NAT MED vol. 8, (11) 1296-1302.

Getting SJ, Christian HC, Flower RJ, Perretti M(2002). Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis. Arthritis Rheum vol. 46, (10) 2765-2775.

Yang YH, Getting SJ, Paul-Clark M, Liu DL, Perretti M, Flower RJ, Morand EF (2002). Annexin I -/- mice are resistant to the anti-inflammatory effect of glucocorticoids. ARTHRITIS AND RHEUMATISM. vol. 46, S388-S388.

Perretti M, Ingegnoli F, Wheller SK, Blades MC, Solito E, Pitzalis C(2002). Annexin 1 modulates monocyte-endothelial cell interaction in vitro and cell migration in vivo in the human SCID mouse transplantation model. J Immunol vol. 169, (4) 2085-2092.

Gibbs L, Carollo MG, Damazo AS, Oliani SM, Perretti M(2002). Time-dependent expression of annexin 1 in a model of chronic granulomatous inflammation. INFLAMM RES vol. 51, (6) 300-306.

Blades MC, Manzo A, Ingegnoli F, Taylor PR, Panayi GS, Irjala H, Jalkanen S, Haskard DO et al.(2002). Stromal cell-derived factor 1 (CXCL12) induces human cell migration into human lymph nodes transplanted into SCID mice. J IMMUNOL vol. 168, (9) 4308-4317.

Calatayud S, Mitchell JA, Perretti M, Giuliano F, Warner TD(2002). Effects of cyclooxygenase-1/cyclooxygenase-2 inhibition on leukocyte/endothelial cell interactions in the rat mesentery. EUR J PHARMACOL vol. 440, (1) 71-77.

Ajuebor MN, Swain MG, Perretti M(2002). Chemokines as novel therapeutic targets in inflammatory diseases. BIOCHEM PHARMACOL vol. 63, (7) 1191-1196.

Perretti M, La M, Solito E (2002). Annexin 1 interacts with L-selectin following neutrophil adhesion to endothelial cells. FASEB J. vol. 16, A1049-A1049.

Getting SJ, Flower RJ, Perretti M (2002). A molecular mechanism for the clinical efficacy of ACTH in controlling human gout: activation of melanocortin type 3 receptor. FASEB J. vol. 16, A591-A591.

Gavins FNE, Gao JL, Murphy PM, Tailor A, Granger DN, Flower RJ, Perretti M (2002). Annexin 1 peptide inhibits ischaemia reperfusion (IR)-induced leukocyte adhesion and emigration: Receptors involved. FASEB J. vol. 16, A598-A599.

La M, Cao T, Hirabayashi J, Kasai K, Chernajovsky Y, Perretti M (2002). Galectin-1 inhibits neutrophil chemotaxis in vitro and migration in vivo: Indication for a novel endogenous anti-inflammatory loop. FASEB J. vol. 16, A598-A598.

Perretti M, Blades MC, Wheller SK, Wahid S, Solito E, Pitzalis C (2002). Monocytic cells over-expressing annexin 1 have reduced transmigration in vitro and elicitation in vivo. FASEB J. vol. 16, A598-A598.

Malcangio M, Getting S, Grist J, Cunningham JR, Bradbury EJ, Issa PC, Lever IJ, Pezet S et al.(2002). A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones. FASEB J vol. 16, (3) 730-+.

Getting SJ, Flower RJ, Perretti M (2002). Activation of melanocortin type 3 receptor as a novel mechanism for ACTH efficacy in gouty arthritis. BRIT J PHARMACOL. vol. 135,

Gavins FNE, Gao J, Murphy PM, Flower RJ, Perretti M (2002). Annexin 1 peptide protects against ischaemia reperfusion in the mouse mesentery. BRIT J PHARMACOL. vol. 135,

La M, Cao T, Chernajovsky Y, Perretti M (2002). Effect of galectin-1 on neutrophil chemotaxis in vitro and migration in vivo. BRIT J PHARMACOL. vol. 135,

Cao T, Day AJ, Perretti M (2002). Link tumor necrosis factor stimulatory gene-6 (LINK_TSG6) has neutrophil anti-migratory effects in-vivo. BRIT J PHARMACOL. vol. 135,

Blades MC, Ingegnoli F, Wheller SK, Manzo A, Wahid S, Panayi GS, Perretti M, Pitzalis C(2002). Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID mice. ARTHRITIS RHEUM vol. 46, (3) 824-836.

Paul-Clark MJ, Mancini L, Del Soldato P, Flower RJ, Perretti M(2002). Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis. P NATL ACAD SCI USA vol. 99, (3) 1677-1682.

Carollo M, Getting SJ, Delaney S, Christie MI, Perretti M (2002). Characterization of CXC and CC chemokine expression in a murine model of chronic granuloma. Inflamm Res. vol. 51, 110-111.

Malcangio M, Getting SJ, Grist J, Cunningham JR, Bradbury EJ, Charbel Issa P, Lever IJ, Pezet S et al.(2002). A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 16, (7) 730-732.

PERRETTI M, Damazo AS, Oliani SM(2002). Annexin 1 localisation in tissue eosinophils as detected by electron microscopy. MEDiators of INFLAMMation. vol. 11, 287-292.

Perretti M, GETTING SJ, Cunningham JR, Bradbury EJ, Malcangio M, Pezet S, Grist J, Lever IJ (2002). Functional evidence that somatostatin release contributes to GDNF anti-hyperalgesic and anti-inflammatory properties. FASEB J. vol. 16, 730-732.

Pitzalis C, Pipitone N, Perretti M (2002). Regulation of leukocyte-endothelial interactions by glucocorticoids. Annals of the New York Academy of Sciences. vol. 966, 108-118.

Ingegnoli F, Blades M, Manzo A, Wahid S, Perretti M, Panayi G, Pitzalis C(2002). Role of cell migration in the pathogenesis of rheumatoid arthritis: in vivo studies in SCID mice transplanted with human synovial membrane. Reumatismo vol. 54, (2) 128-132.

PERRETTI M, Manzo A, Wheller SK, Ingegnoli F, Blades MC, Petzalis C, Wahid S, Panayi GS(2002). Stromal cell derived factor-1 (CXCL 12) induces monocyte migration into human synovium transplanted onto SCID mice. ARTH RHEUM vol. 46, 824-836.

Carollo M, Hogaboam CM, Kunkel SL, Delaney S, Christie MI, Perretti M(2001). Analysis of the temporal expression of chemokines and chemokine receptors during experimental granulomatous inflammation: role and expression of MIP-1alpha and MCP-1. Br J Pharmacol vol. 134, (6) 1166-1179.

Mabley JG, Jagtap P, Perretti M, Getting SJ, Salzman AL, Virag L, Szabo E, Soriano FG et al.(2001). Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase. INFLAMM RES vol. 50, (11) 561-569.

La M, Tailor A, D'Amico M, Flower RJ, Perretti M(2001). Analysis of the protection afforded by annexin 1 in ischaemia-reperfusion injury: focus on neutrophil recruitment. Eur J Pharmacol vol. 429, (1-3) 263-278.

La M, D'Amico M, Bandiera S, Di Filippo C, Oliani SM, Gavins FNE, Flower RJ, Perretti M (2001). Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action. FASEB J. vol. 15, 2247-2256.

Getting SJ, Perretti M(2001). Arthritic diseases: Melanocortin type 3 receptor agonists as potential therapeutics. Current Opinion in Investigational Drugs vol. 2, (8) 1064-1069.

Damazo AS, de Lima WT, Perretti M, Oliani SM(2001). Pharmacological modulation of allergic inflammation in the rat airways and association with mast cell heterogeneity. EUR J PHARMACOL vol. 426, (1-2) 123-130.

Henderson RB, Lim LHK, Tessier PA, Gavins FNE, Mathies M, Perretti M, Hogg N(2001). The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha 4 integrin in the inflammatory response of neutrophils. J EXP MED vol. 194, (2) 219-226.

Perretti M, Getting SJ, Solito E, Murphy PM, Gao JL(2001). Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics. AM J PATHOL vol. 158, (6) 1969-1973.

Diaz B, Barreto E, Cordeiro R, Perretti M, Martins M, Silva P(2001). Enhanced serum glucocorticoid levels mediate the reduction of serosal mast cell numbers in diabetic rats. LIFE SCI vol. 68, (26) 2925-2932.

La M, Bandiera S, Flower RJ, Perretti M (2001). Annexin-1-derived peptides protect against myocardial ischaemia reperfusion injury. BRIT J PHARMACOL. vol. 133, U20-U20.

Calatayud S, Allcock GH, Perretti M, Mitchell JA, Warner TD (2001). Comparison of the effects of the selective COX-2 inhibitor, DFP, and indomethacin on leukocyte-endothelial cell interactions in the rat mesentery. BRIT J PHARMACOL. vol. 133, U102-U102.

Getting SJ, Flower RJ, Perretti M (2001). Effect of melanocortin agonists on joint inflammation. BRIT J PHARMACOL. vol. 133, U19-U19.

Mancini L, MacIntyre I, Perretti M (2001). Glucocorticoids modulate osteoprotegerin/osteoprotegerin ligand and osteoclast activity. BONE. vol. 28, S161-S162.

Perretti M, Wheller SK, Getting SJ, Gao JL (2001). Involvement of FPR in the anti-inflammatory action of annexin-1. BRIT J PHARMACOL. vol. 133, U105-U105.

Goulding NJ, Rajakulendran S, Goulding PN, Perretti M, Flower RJ, Guyre PM (2001). Monocyte CD163 expression is regulated by glucocorticoids and lipopolysaccharide but not by chemokines. BRIT J PHARMACOL. vol. 133, U100-U100.

Solito E, de Coupade C, Canaider S, Goulding NJ, Perretti M(2001). Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation. BRIT J PHARMACOL vol. 133, (2) 217-228.

Blades MC, Ingegnoli F, Manzo A, Wahid S, Haskard D, Panayi G, Perretti M, Pitzalis C(2001). Development of a new model to investigate lymphocyte migration into human peripheral lymph nodes (HPLN) transplanted into SCID mice. RHEUMATOLOGY vol. 40, 66-66.

Mabley J, Virag L, Jagtap P, Szabo E, Prendergast R, Perretti M, Getting S, Szabo C (2001). Effect of a novel poly (ADP-ribose) polymerase (PARP) inhibitor in rodent models of local inflammation. FASEB J. vol. 15, A242-A242.

Perretti M, Wheller SK, Getting SJ, Gao JL (2001). Interaction with the formylated receptor (FPR) is at the basis of annexin 1 anti-inflammatory effects. FASEB J. vol. 15, A681-A681.

Oliani SM, Paul-Clark MJ, Christian HC, Flower RJ, Perretti M(2001). Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression. AM J PATHOL vol. 158, (2) 603-615.

Oliani SM, Perretti M (2001). Cell localization of the anti-inflammatory protein annexin 1 during experimental inflammatory response. Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia. vol. 106, 69-77.

PERRETTI M, Solito E, Russo-Marie F, de Coupade C, Ajuebor MN(2001). Cytokine modulation of liver annexin 1 expression during experimental endotoxemia. AM J PATHOL vol. 159, 1435-1443.

PERRETTI M, Obinger C, Furtmuller PG, Allegra M, Regelsberger G, Livrea MA, Tesoriere L, Turco-Leveri ML(2001). Mechanism of Reaction of Melatonin with Human Myeloperoxidase. Biochem Biophys Res commun. vol. 282, 380-386.

Oliani SM, Lim LHK, Christian HC, Pell K, Das AM, Perretti M(2001). Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction. CELL BIOL INT vol. 25, (8) 795-803.

Getting SJ, Allcock GH, Flower R, Perretti M(2001). Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties. J Leukoc Biol vol. 69, (1) 98-104.

Allcock GH, Allegra M, Flower RJ, Perretti M(2001). Neutrophil accumulation induced by bacterial lipopolysaccharide: effects of dexamethasone and annexin 1. CLIN EXP IMMUNOL vol. 123, (1) 62-67.

Mancini L, Moradi-Bidhendi N, Brandi ML, Perretti M, MacIntyre I(2000). Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin. BIOCHEM BIOPH RES CO vol. 279, (2) 391-397.

Mancini L, MacIntyre L, Brandi ML, Perretti M (2000). Analysis of osteoprotegerin ligand effects on the FLG 29.1 pre-osteoclastic cell line. BRIT J PHARMACOL. vol. 131, U15-U15.

Carollo M, Christie MI, Perretti M (2000). Expression of MIP-2, KC and MCR-1 and their receptors in chronic granulomatous inflammation. BRIT J PHARMACOL. vol. 131, U13-U13.

McLean PG, Perretti M, Ahluwalia A(2000). Kinin B<inf>1</inf> receptors and the cardiovascular system: Regulation of expression and function. Cardiovascular Research vol. 48, (2) 194-210.

McLean PG, Ahluwalia A, Perretti M(2000). Association between kinin B<inf>1</inf> receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules. Journal of Experimental Medicine vol. 192, (3) 367-380.

Getting SJ, Perretti M(2000). MC3-R as a novel target for antiinflammatory therapy. Drug News and Perspectives vol. 13, (1) 19-27.

McLean PG, Perretti M, Ahluwalia A(2000). Kinin B<inf>1</inf> receptors as novel anti-inflammatory targets. Expert Opinion on Therapeutic Targets vol. 4, (2) 127-141.

Canaider S, Solito E, De Coupade C, Flower RJ, Russo-Marie F, Goulding NJ, Perretti M(2000). Increased apoptosis in U937 cells over-expressing lipocortin I (annexin I). Life Sciences vol. 66, (18)

Paul-Clark M, Del Soldato P, Fiorucci S, Flower RJ, Perretti M(2000). 21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties. British Journal of Pharmacology vol. 131, (7) 1345-1354.

Oliani SM, Christian HC, Manston J, Flower RJ, Perretti M(2000). An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: Modulation by inflammation and dexamethasone. Laboratory Investigation vol. 80, (9) 1429-1438.

Perretti M, Christian H, Wheller SK, Aiello I, Mugridge KG, Morris JF, Flower RJ, Goulding NJ(2000). Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis. Cell Biology International vol. 24, (3) 163-174.

Lim LHK, Flower RJ, Perretti M, Das AM(2000). Glucocorticoid receptor activation reduces CD11b and CD49d levels on murine eosinophils: Characterization and functional relevance. American Journal of Respiratory Cell and Molecular Biology vol. 22, (6) 693-701.

Perretti M, Page CP(2000). Heparin and inflammation: a new use for an old GAG?. Gut vol. 47, (1) 14-15.

D'Amico M, Di Filippo C, La M, Solito E, Mclean PG, Flower RJ, Oliani SM, Perretti M(2000). Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leulkocyte. FASEB Journal vol. 14, (13) 1867-1869.

Perretti M, Ahluwalia A(2000). The microcirculation and inflammation: Site of action for glucocorticoids. Microcirculation vol. 7, (3) 147-161.

McLean PG, Perretti M, Ahluwalia A(1999). Inducible expression of the kinin B<inf>1</inf> receptor in the endotoxemic heart: Mechanisms of des-Arg⁹bradykinin-induced coronary vasodilation. British Journal of Pharmacology vol. 128, (2) 275-282.

Das AM, Ajuebor MN, Flower RJ, Perretti M, McColl SR(1999). Contrasting roles for RANTES and macrophage inflammatory protein-1α (MIP-1α) in a murine model of allergic peritonitis. Clinical and Experimental Immunology vol. 117, (2) 223-229.

Getting SJ, Gibbs L, Clark AJL, Flower RJ, Perretti M(1999). POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. Journal of Immunology vol. 162, (12) 7446-7453.

Ruetten H, Thiemermann C, Perretti M(1999). Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-κB but not protein tyrosine kinase: Comparison to induction of iNOS. Mediators of Inflammation vol. 8, (2) 77-84.

Ahluwalia A, Perretti M(1999). B<inf>1</inf> receptors as a new inflammatory target. Could this B the 1?. Trends in Pharmacological Sciences vol. 20, (3) 100-104.

Ajuebor MN, Das AM, Virág L, Szabó C, Perretti M(1999). Regulation of macrophage inflammatory protein-1α expression and function by endogenous interleukin-10 in a model of acute inflammation. Biochemical and Biophysical Research Communications vol. 255, (2) 279-282.

Ajuebor MN, Das AM, Virág L, Flower RJ, Szabó C, Perretti M(1999). Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: Evidence for an inhibitory loop involving endogenous IL-10. Journal of Immunology vol. 162, (3) 1685-1691.

Getting SJ, Flower RJ, Perretti M (1999). Agonism at melanocortin receptor type 3 on macrophages inhibits neutrophil influx. Inflammation Research. vol. 48,

Tailor A, Tomlinson A, Salas A, Panés J, Granger DN, Flower RJ, Perretti M(1999). Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: Role of intercellular adhesion molecule 1 and KC. Gut vol. 45, (5) 705-712.

Euzger HS, Flower RJ, Goulding NJ, Perretti M(1999). Differential modulation of annexin I binding sites on monocytes and neutrophils. Mediators of Inflammation vol. 8, (1) 53-62.

Minghetti L, Nicolini A, Polazzi E, Greco A, Perretti M, Parente L, Levi G(1999). Down-regulation of microglial cyclo-oxygenase-2 and inducible nitric oxide synthase expression by lipocartin 1. British Journal of Pharmacology vol. 126, (6) 1307-1314.

Perretti M, Wheller SK, Flower RJ, Wahid S, Pitzalis C(1999). Modulation of cellular annexin I in human leukocytes infiltrating DTH skin reactions. Journal of Leukocyte Biology vol. 65, (5) 583-589.

Ajuebor MN, Virág L, Flower RJ, Perretti M, Szabó C(1998). Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation. Immunology vol. 95, (4) 625-630.

Lim LHK, Solito E, Russo-Marie F, Flower RJ, Perretti M(1998). Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: Effect of lipocortin 1. Proceedings of the National Academy of Sciences of the United States of America vol. 95, (24) 14535-14539.

Goulding NJ, Euzger HS, Butt SK, Perretti M (1998). Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. Inflammation Research. vol. 47,

Perretti M(1998). Lipocortin 1 and chemokine modulation of granulocyte and monocyte accumulation in experimental inflammation. General Pharmacology vol. 31, (4) 545-552.

Ajuebor MN, Gibbs L, Flower RJ, Das AM, Perretti M(1998). Investigation of the functional role played by the chemokine monocyte chemoattractant protein-1 in interleukin-1-induced murine peritonitis. British Journal of Pharmacology vol. 125, (2) 319-326.

Ahluwalia A, De Felipe C, O'Brien J, Hunt SP, Perretti M(1998). Impaired IL-1β-induced neutrophil accumulation in tachykinin NK<inf>1</inf> receptor knockout mice. British Journal of Pharmacology vol. 124, (6) 1013-1015.

Pistritto G, Mancuso C, Tringali G, Perretti M, Preziosi P, Navarra P(1998). The relative contribution of constitutive and inducible cyclooxygenase activity to lipopolysaccharide-induced prostaglandin production by primary cultures of rat hypothalamic astrocytes. Neuroscience Letters vol. 246, (1) 45-48.

Teixeira MM, Das AM, Miotla JM, Perretti M, Hellewell PG(1998). The role of lipocortin-1 in the inhibitory action of dexamethasone on eosinophil trafficking in cutaneous inflammatory reactions in the mouse. British Journal of Pharmacology vol. 123, (3) 538-544.

Bryant CE, Perretti M, Flower RJ(1998). Suppression by dexamethasone of inducible nitric oxide synthase protein expression in vivo. A possible role for lipocortin 1. Biochemical Pharmacology vol. 55, (3) 279-285.

Ajuebor MN, Flower RJ, Hannon R, Christie M, Bowers K, Verity A, Perretti M(1998). Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model. Journal of Leukocyte Biology vol. 63, (1) 108-116.

Das AM, Flower RJ, Perretti M(1998). Resident mast cells are important for eotaxin-induced eosinophil accumulation in vivo. Journal of Leukocyte Biology vol. 64, (2) 156-162.

Das AM, Lim LHK, Flower RJ, Perretti M(1997). Dexamethasone reduces cell surface levels of CD11b on human eosinophils. Mediators of Inflammation vol. 6, (5-6) 363-367.

Cuzzocrea S, Tailor A, Zingarelli B, Salzman AL, Flower RJ, Szabó C, Perretti M(1997). Lipocortin 1 Protects Against Splanchnic Artery Occlusion and Reperfusion Injury by Affecting Neutrophil Migration. Journal of Immunology vol. 159, (10) 5089-5097.

Perretti M(1997). Endogenous mediators that inhibit the leukocyte-endothelium interaction. Trends in Pharmacological Sciences vol. 18, (11) 418-425.

Szabó C, Lim LHK, Cuzzocrea S, Getting SJ, Zingarelli B, Flower RJ, Salzman AL, Perretti M(1997). Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. Journal of Experimental Medicine vol. 186, (7) 1041-1049.

Das AM, Flower RJ, Perretti M(1997). Eotaxin-Induced Eosinophil Migration in the Peritoneal Cavity of Ovalbumin-Sensitized Mice: Mechanism of Action. Journal of Immunology vol. 159, (3) 1466-1473.

Wheller SK, Perretti M(1997). Dexamethasone inhibits cytokine-induced intercellular adhesion molecule-1 up-regulation on endothelial cell lines. European Journal of Pharmacology vol. 331, (1) 65-71.

Ferreira SH, Cunha FQ, Lorenzetti BB, Michelin MA, Perretti M, Flower RJ, Poole S(1997). Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone. British Journal of Pharmacology vol. 121, (5) 883-888.

Tailor A, Das AM, Getting SJ, Flower RJ, Perretti M(1997). Subacute treatment of rats with dexamethasone reduces ICAM-1 levels on circulating monocytes. Biochemical and Biophysical Research Communications vol. 231, (3) 675-678.

Das AM, Flower RJ, Hellewell PG, Teixeira MM, Perretti M(1997). A novel murine model of allergic inflammation to study the effect of dexamethasone on eosinophil recruitment. British Journal of Pharmacology vol. 121, (1) 97-104.

Tailor A, Flower RJ, Perretti M(1997). Dexamethasone inhibits leukocyte emigration in rat mesenteric post- capillary venules: An intravital microscopy study. Journal of Leukocyte Biology vol. 62, (3) 301-308.

Getting SJ, Flower RJ, Perretti M(1997). Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. British Journal of Pharmacology vol. 120, (6) 1075-1082.

Getting SJ, Flower RJ, Parente L, De Medicis R, Lussier A, Woliztky BA, Martins MA, Perretti M(1997). Molecular determinants of monosodium urate crystal-induced murine peritonitis: A role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. Journal of Pharmacology and Experimental Therapeutics vol. 283, (1) 123-130.

Perretti M, Croxtall JD, Wheller SK, Goulding NJ, Hannon R, Flower RJ(1996). Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. Nature Medicine vol. 2, (11) 1259-1262.

Perretti M, Wheller SK, Harris JG, Flower RJ(1996). Modulation of ICAM-1 levels on U-937 cells and mouse macrophages by interleukin-1β and dexamethasone. Biochemical and Biophysical Research Communications vol. 223, (1) 112-117.

Harris JG, Flower RJ, Watanabe K, Tsurufuji S, Wolitzky BA, Perretti M(1996). Relative contribution of the selectins in the neutrophil recruitment caused by the chemokine cytokine-induced neutrophil chemoattractant (CINC). Biochemical and Biophysical Research Communications vol. 221, (3) 692-696.

Malcangio M, Bowery NG, Flower RJ, Perretti M(1996). Effect of interleukin-1β on the release of substance P from rat isolated spinal cord. European Journal of Pharmacology vol. 299, (1-3) 113-118.

Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK, Flower RJ(1996). Acute inflammatory response in the mouse: Exacerbation by immunoneutralization of lipocortin 1. British Journal of Pharmacology vol. 117, (6) 1145-1154.

Harris JG, Flower RJ, Watanabe K, Tsurufuji S, Wolitzky BA, Perretti M(1996). Erratum: Relative contribution of the selectins in the neutrophil recruitment caused by the chemokine cytokine-induced neutrophil chemoattractant (CINC) (Biochemical and Biophysical Research Communications (1996) 221 3 (692-696)). Biochemical and Biophysical Research Communications vol. 224, (3) 878-879.

Ahluwalia A, Perretti M(1996). Involvement of bradykinin B<inf>1</inf> receptors in the polymorphonuclear leukocyte accumulation induced by IL-1β in vivo in the mouse. Journal of Immunology vol. 156, (1) 269-274.

Perretti M, Flower RJ(1996). Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: Modulation by glucocorticoids and inflammation. British Journal of Pharmacology vol. 118, (3) 605-610.

Perretti M, Wheller SK, Choudhury Q, Croxtall JD, Flower RJ(1995). Selective inhibition of neutrophil function by a peptide derived from lipocortin 1 N-terminus. Biochemical Pharmacology vol. 50, (7) 1037-1042.

Harris JG, Flower RJ, Perretti M(1995). Endogenous corticosteroids mediate the neutrophilia caused by platelet-activating factor in the mouse. European Journal of Pharmacology vol. 283, (1-3) 9-18.

Klemm P, Harris HJ, Perretti M(1995). Effect of rolipram in a murine model of acute inflammation: comparison with the corticoid dexamethasone. European Journal of Pharmacology vol. 281, (1) 69-74.

Palmi M, Frosini M, Sgaragli GP, Becherucci C, Perretti M, Parente L(1995). Inhibition of interleukin-1β-induced pyresis in the rabbit by peptide 204-212 of lipocortin 5. European Journal of Pharmacology vol. 281, (1) 97-99.

Harris JG, Flower RJ, Perretti M(1995). Alteration of neutrophil trafficking by a lipocortin 1 N-terminus peptide. European Journal of Pharmacology vol. 279, (2-3) 149-157.

Wu CC, Croxtall JD, Perretti M, Bryant CE, Thiemermann C, Flower RJ, Vane JR(1995). Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proceedings of the National Academy of Sciences of the United States of America vol. 92, (8) 3473-3477.

Perretti M, Flower RJ (1995). Anti-inflammatory lipocortin-derived peptides. Agents and Actions. vol. 46, 131-138.

Perretti M, Szabó C, Thiemermann C(1995). Effect of interleukin‐4 and interleukin‐10 on leucocyte migration and nitric oxide production in the mouse. British Journal of Pharmacology vol. 116, (4) 2251-2257.

Mugridge KG, Perretti M, Ghiara P, Galeotti CL, Melli M, Parente L(1995). Gastric antisecretory and anti-ulcer actions of IL-1 in rat involve different IL-1 receptor types. American Journal of Physiology - Gastrointestinal and Liver Physiology vol. 269, (5 32-5)

Mancuso F, Flower RJ, Perretti M(1995). Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule: Involvement of endogenous lipocortin 1. Journal of Immunology vol. 155, (1) 377-386.

Ahluwalia A, Perretti M(1994). Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse. European Journal of Pharmacology vol. 264, (3) 407-415.

Perretti M(1994). Lipocortin-derived peptides. Biochemical Pharmacology vol. 47, (6) 931-938.

Szabó C, Thiemermann C, Wu CC, Perretti M, Vane JR(1994). Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proceedings of the National Academy of Sciences of the United States of America vol. 91, (1) 271-275.

Perretti M, Harris JG, Flower RJ(1994). A role for endogenous histamine in interleukin‐8‐induced neutrophil infiltration into mouse air‐pouch: investigation of the modulatory action of systemic and local dexamethasone. British Journal of Pharmacology vol. 112, (3) 801-808.

Ahluwalia A, Perretti M(1994). Anti-inflammatory effect of prostanoids in mouse and rat skin: Evidence for a role of EP<inf>3</inf>-receptors. Journal of Pharmacology and Experimental Therapeutics vol. 268, (3) 1526-1531.

Perretti M, Flower RJ(1994). Cytokines, glucocorticoids and lipocortins in the control of neutrophil migration. Pharmacological Research vol. 30, (1) 53-59.

Perretti M, Ahluwalia A, Flowers RJ, Manzini S(1993). Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: Involvement of NK-1 receptors. Immunology vol. 80, (1) 73-77.

Perretti M, Appleton I, Parente L, Flower RJ (1993). Pharmacology of interleukin-1-induced neutrophil migration. Agents and Actions. vol. 38,

Cirino G, Cicala C, Sorrentino L, Ciliberto G, Arpaia G, Perretti M, Flower RJ(1993). Anti‐inflammatory actions of an N‐terminal peptide from human lipocortin 1. British Journal of Pharmacology vol. 108, (3) 573-574.

Becherucci C, Solito E, Parente L, Galeotti CL, Perretti M(1993). Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5. Mediators of Inflammation vol. 2, (2) 109-113.

Becherucci C, Parente L, Perretti M, Mugridge KG(1993). Inhibition of smooth muscle contraction and platelet aggregation by peptide 204-212 of lipocortin 5: an attempt to define some structure requirements. Mediators of Inflammation vol. 2, (2) 103-107.

Perretti M, Ahluwalia A, Harris JG, Goulding NJ, Flower RJ(1993). Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil- dependent edema in the mouse: A qualitative comparison with an anti-CD11b monoclonal antibody. Journal of Immunology vol. 151, (8) 4306-4314.

Perretti M, Flower RJ(1993). Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. Journal of Immunology vol. 150, (3) 992-999.

Thiemermann C, Wu C, Szabó C, Perretti M, Vane JR(1993). Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. British Journal of Pharmacology vol. 110, (1) 177-182.

Perretti M, Duncan GS, Flower RJ, Peers SH(1993). Serum corticosterone, interleukin‐1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains. British Journal of Pharmacology vol. 110, (2) 868-874.

Da Silva JAP, Peers SH, Perretti M, Willoughby DA(1993). Sex steroids affect glucocorticoid response to chronic inflammation and to interleukin-1. Journal of Endocrinology vol. 136, (3) 389-397.

Perretti M, Flower RJ, Goulding NJ(1993). The ability of murine leukocytes to bind lipocortin 1 is lost during acute inflammation. Biochemical and Biophysical Research Communications vol. 192, (2) 345-350.

Croxtall J, Flower R, Perretti M (1992). The role of lipocortin 1 in the regulation of A549 cell proliferation and leukocyte migration. Journal of Lipid Mediators. vol. 6, 295-302.

Becherucci C, Perretti M, Nencioni L, Silvestri S, Parente L(1992). Anti-inflammatory effect of tuftsin and its retro-inverso analogue in rat adjuvant arthritis. Agents and Actions vol. 36, (1 Supplement)

Perretti M, Solito E, Parente L(1992). Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice. Agents and Actions vol. 35, (1-2) 71-78.

Parente L, Perretti M, Wallace JL, Mugridge KG(1992). Mechanism of the protective action of interleukin-1 in the experimental gastric damage in the rat. Pharmacological Research vol. 26, (SUPPL. 2) 28-29.

Douglas GJ, Flower RJ, Parente L, Perretti M(1992). Peptide 204-212 of lipocortin 5 inhibits the generation of a prostacyclin-like factor from rat aorta preparations in vitro. Prostaglandins vol. 44, (5) 381-388.

Perretti M, Mugridge KG, Wallace JL, Parente L(1992). Reduction of aspirin-induced gastric damage in rats by interleukin-1β: Possible involvement of endogenous corticosteroids. Journal of Pharmacology and Experimental Therapeutics vol. 261, (3) 1238-1247.

Verdini AS, Pinori M, Silvestri S, Becherucci C, Longobardi MG, Parente L, Peppoloni S, Perretti M et al.(1991). Immunostimulation by a Partially Modified retro -in verso -Tuftsin Analogue Containing Thr¹ψ[NHCO](R,S)Lys² Modification. Journal of Medicinal Chemistry vol. 34, (12) 3372-3379.

Mugridge KG, Perretti M, Ghiara P, Parente L(1991). α-melanocyte-stimulating hormone reduces interleukin-lβ effects on rat stomach preparations possibly through interference with a type I receptor. European Journal of Pharmacology vol. 197, (2-3) 151-155.

Mugridge KG, Perretti M, Parente L(1991). 5-Lipoxygenase activation may facilitate an interleukin-1 transduction signal. Advances in prostaglandin, thromboxane, and leukotriene research vol. 21 B, 517-520.

Piaz VD, Ciciani G, Turco G, Giovannoni MP, Miceli M, Pirisino R, Perretti M(1991). 5‐Acyl‐6‐Aryl‐4‐Nitro‐3(2HH)Pyridazinones and related 4‐amino compounds: Synthesis and pharmacological evaluation. Journal of Pharmaceutical Sciences vol. 80, (4) 341-348.

Perretti M, Becherucci C, Mugridge KG, Solito E, Silvestri S, Parente L(1991). A novel anti‐inflammatory peptide from human lipocortin 5. British Journal of Pharmacology vol. 103, (2) 1327-1332.

Perretti M, Mugridge KG, Becherucci C, Parente L(1991). Evidence that interleukin-1 and lipoxygenase metabolites mediate the lethal effect of complete Freund's adjuvant in adrenalectomized rats. Lymphokine and Cytokine Research vol. 10, (4) 239-243.

Mugridge KG, Perretti M, Becherucci C, Parente L(1991). Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: Implications for increased phospholipase-A<inf>2</inf> activity via stimulation of 5-lipoxygenase. Journal of Pharmacology and Experimental Therapeutics vol. 256, (1) 29-37.

Perretti M, Mugridge KG, Becherucci C, Silvestri S, Parente L(1990). Antiulcer property of human recombinant interleukin-1β. Pharmacological Research vol. 22,

Parente L, Becherucci C, Perretti M, Solito E, Mugridge KG, Galeotti CL, Raugei G, Melli M et al.(1990). Are the lipocortins the second messengers of the anti-inflammatory action of glucocorticoids?. Progress in clinical and biological research vol. 349, 55-68.

Becherucci C, Perretti M, Galeotti C, Parente L(1990). Different anti-inflammatory effects of lipocortins 1 and 5. Pharmacological Research vol. 22,

Parente L, Mugridge KG, Perretti M, Solito E(1990). In vitro and in vivo activation of phospholipase A<inf>2</inf> by interleukin-1. Pharmacological Research vol. 22,

Perretti M, Nuti S, Parente L(1990). Investigation of rat mast cell degranulation using flow cytometry. Journal of Pharmacological Methods vol. 23, (3) 187-194.

Becherucci C, Solito E, Perretti M, Mugridge KG, Galeotti CL, Parente L(1990). Purification and biological activity of human lipocortin 2. Pharmacological Research vol. 22, (SUPPL. 1) 29-30.

Becherucci C, Donati D, Perretti M, Parente L(1989). The release of interleukin-1-like activity by macrophages in two models of immunological inflammation in the rat. Agents and Actions vol. 28, (3-4) 243-247.

Perretti M, Becherucci C, Scapigliati G, Parente L(1989). The effect of adrenalectomy on interleukin-1 release in vitro and in vivo. British Journal of Pharmacology vol. 98, (4) 1137-1142.

Ignesti G, Perretti M, Buffoni F(1988). Induction and quail liver diamine oxidase (histaminase). Part I: Interference of spermidine synthase on the diamine oxidase activity assay using putrescine as substrate. Agents and Actions vol. 25, (1-2) 37-42.

Ignesti G, Buffoni F, Perretti M, Cintelli A(1988). Induction and quail liver diamine oxidase (histaminase). Part II: Different responses to the inducers. Agents and Actions vol. 25, (1-2) 43-47.

Perretti M, Becherucci C, Parente L(1988). Interleukin-1 release by macrophages from adrenalectomized (ADX) and shamoperated (SHO) rats. Pharmacological Research Communications vol. 20, (SUPPL. 2)

Becherucci C, Donati D, Perretti M, Parente L(1988). Interleukin-1 release by rat macrophages in experimental immunological inflammation. Pharmacological Research Communications vol. 20, (SUPPL. 2)

Ignesti G, Perretti M, Buffoni F(1986). Diamine oxidase activity in Japanese quail liver induced with Aroclor 1254. Agents and Actions vol. 18, (1-2) 41-43.

Bombardieri G, Bevilacqua E, Conti LR, Innocenti P, Perretti MA(1981). Plasma amine oxidases in Wilson's disease. Life Sciences vol. 29, (2) 117-120.