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Publications:  Prof Michael Philpott

Zhang R, Yang K, Yang B, AbuAli NA, Hayajneh M, Philpott M, Abbasi QH, Alomainy A(2019). Dielectric and Double Debye Parameters of Artificial Normal Skin and Melanoma. Journal of Infrared, Millimeter, and Terahertz Waves vol. 40, (6) 657-672.
10.1007/s10762-019-00597-x
Bladen JC, Wang J, Sangaralingam A, Moosajee M, Fitchett C, Chelala C, Beaconsfield M, O'Toole EA et al.(2018). MicroRNA and transcriptome analysis in periocular Sebaceous Gland Carcinoma. Scientific Reports vol. 8, (1)
10.1038/s41598-018-25900-z
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44983
Fang L, Trigiante G, Kousseff CJ, Crespo-Otero R, Philpott MP, Watkinson M(2018). Biotin-tagged fluorescent sensor to visualize 'mobile' Zn2+ in cancer cells. Chem Commun (Camb)
10.1039/c8cc05425h
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43649
Rahman MM, Hazan A, Selway JL, Herath DS, Harwood CA, Pirzado MS, Atkar R, Kelsell DP et al.(2018). A novel mechanism for activation of GLI1 by nuclear SMO that escapes anti-SMO inhibitors. Cancer Research vol. 78, (10) 2577-2588.
10.1158/0008-5472.CAN-17-2897
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42287
Kenny FN, Drymoussi Z, Delaine-Smith R, Kao AP, Laly AC, Knight MM, Philpott MP, Connelly JT(2018). Tissue stiffening promotes keratinocyte proliferation through activation of epidermal growth factor signaling. Journal of Cell Science vol. 131, (10)
10.1242/jcs.215780
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39445
Philpott MP(2018). Culture of the human pilosebaceous unit, hair follicle and sebaceous gland. Exp Dermatol vol. 27, (5) 571-577.
10.1111/exd.13669
Bladen JC, Moosajee M, Tracey-White D, Beaconsfield M, O'Toole EA, Philpott MP(2018). Analysis of hedgehog signaling in periocular sebaceous carcinoma. Graefes Arch Clin Exp Ophthalmol vol. 256, (4) 853-860.
10.1007/s00417-018-3900-5
Caton PW, Evans EA, Philpott MP, Hannen RF(2017). Can the skin make you fat? A role for the skin in regulating adipose tissue function and whole-body glucose and lipid homeostasis. Curr Opin Pharmacol vol. 37, 59-64.
10.1016/j.coph.2017.08.011
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55589
Milligan D, Newman J, Caley M, Wainwright L, Jenkins G, Philpott M, Bishop C (2017). Development of a 3D living skin equivalent to explore the influence of senescence on the skin ageing phenotype. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 137, S310-S310.
10.1016/j.jid.2017.07.359
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51123
Figlak K, Paus R, Philpott M (2017). Glycogen metabolism and Cori cycle in human hair follicles. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 137, S238-S238.
10.1016/j.jid.2017.07.264
Shah KF, Davis M, Philpott M (2017). Investigation into the role of HIF-1A stabilisation in hair follicle metabolism. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 137, S241-S241.
10.1016/j.jid.2017.07.278
Hannen RF, Asher S, Mannella V, Purdie K, Leigh I, Philpott M (2017). Stressed out keratinocytes, new insights into psoriasis lesion formation. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 137, S215-S215.
10.1016/j.jid.2017.07.441
Vootukuri R, Trigiante G, Philpott M (2017). Wound Healing properties of OPAL A (patented Carica papaya fruit extract). JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 137, S309-S309.
10.1016/j.jid.2017.07.356
Evans E, Kodji X, Sayers S, Brain S, Philpott M, Hannen R, Caton P (2017). A novel skin-adipose tissue axis regulates pancreatic beta cell function. DIABETOLOGIA. vol. 60, S12-S12.
Hannen R, Udeh-Momoh C, Upton J, Wright M, Michael A, Gulati A, Rajpopat S, Clayton N et al.(2017). Dysfunctional Skin-Derived Glucocorticoid Synthesis Is a Pathogenic Mechanism of Psoriasis. Journal of Investigative Dermatology vol. 137, (8) 1630-1637.
10.1016/j.jid.2017.02.984
https://qmro.qmul.ac.uk/xmlui/handle/123456789/53643
Pantazi E, Gemenetzidis E, Teh MT, Reddy SV, Warnes G, Evagora C, Trigiante G, Philpott MP(2017). GLI2 Is a Regulator of β-Catenin and Is Associated with Loss of E-Cadherin, Cell Invasiveness, and Long-Term Epidermal Regeneration. Journal of Investigative Dermatology vol. 137, (8) 1719-1730.
10.1016/j.jid.2016.11.046
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22394
PHILPOTT MP, Ojeh N, Tomic-Canic M, Akgül B, Navsaria H(2017). In vitro skin models to study epithelial regeneration from the hair follicle. PLoS ONE
10.1371/journal.pone.0174389
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22481
Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EGY et al.(2017). Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. Nature Communications vol. 8,
10.1038/ncomms14694
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22359
Evans EA, Sayers SR, Philpott MP, Hannen RF, Caton PW (2017). A novel skin-adipose tissue axis regulates pancreatic beta cell function. vol. 34, is. Special Issue 1, pp. 42-42. Abstract: java.sql.Clob org.hibernate.engine.jdbc.WrappedClob java.io.Serializable ,
Publisher URL
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56033
Hannen RF, Perez P, Lightman S, Philpott MP (2016). Stabilising the Glucocorticoid Response in Psoriatic Skin. vol. 175, pp. 45-45.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55346
Chopra N, Yang K, Upton J, Abbasi QH, Qaraqe K, Philpott M, ALOMAINY AHM(2016). Fibroblasts Cell Number Density based Human Skin Characterization at THz for In-body Nanonetworks. Elsevier Nano Communication Networks
10.1016/j.nancom.2016.07.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15918
Chopra N, Upton J, Philpott M, Alomainy A, Abbasi QH, Qaraqe K (2016). Characterization of volumetric change in collagen using THz time domain spectroscopy for in-body nanonetworks. Proceedings of the 3rd ACM International Conference on Nanoscale Computing and Communication, ACM NANOCOM 2016.
10.1145/2967446.2967471
Figlak K, Paus R, Philpott M (2016). Towards dissecting the role of glycogen metabolism in human hair follicle biology. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S196-S196.
10.1016/j.jid.2016.06.223
Chopra N, Yang K, Abbasi QH, Qaraqe KA, Philpott M, Alomainy A(2016). THz time-domain spectroscopy of human skin tissue for in-body nanonetworks. IEEE Transactions on Terahertz Science and Technology vol. PP, (99)
10.1109/TTHZ.2016.2599075
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15418
Reddy SV, Philpott MP, Trigiante G(2016). Retaining in-gel zymographic activity of cysteine proteases via a cysteine supplemented running buffer. Electrophoresis
10.1002/elps.201600188
Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP et al.(2016). Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. Journal of Investigative Dermatology vol. 136, (7) 1460-1470.
10.1016/j.jid.2016.03.016
https://qmro.qmul.ac.uk/xmlui/handle/123456789/27303
Chew EGY, Tan JHJ, Bahta AW, Ho BS-Y, Liu X, Lim TC, Sia YY, Bigliardi PL et al.(2016). Differential expression between human dermal papilla cells from balding and non-balding scalps reveals new candidate genes for androgenetic alopecia. Journal of Investigative Dermatology
10.1016/j.jid.2016.03.032
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12536
Langan EA, Philpott MP, Kloepper JE, Paus R(2015). Human hair follicle organ culture: theory, application and perspectives. Exp Dermatol vol. 24, (12) 903-911.
10.1111/exd.12836
Yang K, Chopra N, Upton J, Hao Y, Philpott M, Alomainy A, Abbasi QH, Qaraqe K (2015). Characterising skin-based nano-networks for healthcare monitoring applications at THz. IEEE Antennas and Propagation Society, AP-S International Symposium (Digest). vol. 2015-October, 199-200.
10.1109/APS.2015.7304485
Hannen R, Udeh-Momoh C, Upton J, Sevilla L, Lightman S, Perez P, Philpott M (2015). Beyond the Adrenal Gland: The Essential Role of Skin-Synthesised Glucocorticoids in Health and Disease. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S8-S8.
Upton JH, Hannen RF, Bahta AW, Farjo N, Farjo B, Philpott MP(2015). Oxidative stress-associated senescence in dermal papilla cells of men with androgenetic alopecia. J Invest Dermatol vol. 135, (5) 1244-1252.
10.1038/jid.2015.28
Chopra N, Yang K, Upton J, Alomainy A, Philpott M, Hao Y (2015). Understanding and characterizing nanonetworks for healthcare monitoring applications. Conference Proceedings - 2014 IEEE MTT-S International Microwave Workshop Series on: RF and Wireless Technologies for Biomedical and Healthcare Applications, IMWS-Bio 2014.
10.1109/IMWS-BIO.2014.7032446
Chopra N, Yang K, Philpott M, Alomainy A, Abbasi QH, Qaraqe K (2015). Characterization of human skin using Thz time domain spectroscopy for in-body nanonetworks. EAI International Conference on Bio-inspired Information and Communications Technologies (BICT).
10.4108/eai.3-12-2015.2262500
Hannen R, Udeh C, Rajpopat S, Perez P, Philpott M (2014). Deficiency of the local cortisol stress response pathway in psoriatic skin. BRITISH JOURNAL OF DERMATOLOGY. vol. 171, E170-E171.
Chew EG, Hillmer AM, Tan JH, Philpott MP, Bahta AW (2014). Androgenetic Alopecia: Analysis of transcriptome differences between balding and non-balding human dermal papilla cells. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S67-S67.
Al-Nuaimi Y, Hardman JA, Bíró T, Haslam IS, Philpott MP, Tóth BI, Farjo N, Farjo B et al.(2014). A meeting of two chronobiological systems: circadian proteins Period1 and BMAL1 modulate the human hair cycle clock. J Invest Dermatol vol. 134, (3) 610-619.
10.1038/jid.2013.366
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al.(2014). GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis. Cell Death Dis vol. 5,
10.1038/cddis.2013.535
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11129
Sully K, Akinduro O, Philpott MP, Naeem AS, Harwood CA, Reeve VE, O'Shaughnessy RF, Byrne C(2013). The mTOR inhibitor rapamycin opposes carcinogenic changes to epidermal Akt1/PKBα isoform signaling. Oncogene vol. 32, (27) 3254-3262.
10.1038/onc.2012.338
Harrison W, Cochrane B, Neill G, Philpott M(2013). The oncogenic GLI transcription factors facilitate keratinocyte survival and transformation upon exposure to genotoxic agents. Oncogene
10.1038/onc.2013.199
Al-Nuaimi Y, Hardman JA, Haslam IS, Biro T, Toth BI, Farjo N, Farjo B, Philpott M et al. (2013). A meeting of two chronobiological systems: Period1 and BMAL1 modulate the human hair cycle. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, 1416-1416.
Akinduro O, Sully K, Chikh A, O'shaughnessy RF, Bergamaschi D, Harwood CA, Philpott MP, Byrne C (2013). Constitutive autophagy as a terminal differentiation mechanism. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S127-S127.
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao E, Ikram M, Neill G et al. (2013). GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S57-S57.
10.1038/cddis.2013.535
Rahman M, Selway J, Herath D, Hazan A, Roy A, Langlands K, Edmunds S, Kelsell D et al. (2013). Gene expression profiling demonstrates that the effects of PTCH1 suppression are not fully reversed upon pharmacological inhibition of SMOOTHENED in human keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S68-S68.
Hannen R, Nikitorowicz-Buniak J, Stratton R, Ahmed A, Rajpopat S, Philpott M (2013). Loss of the local cortisol stress response pathway contributes to the pathogenesis inflammatory skin diseases. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S116-S116.
Drymoussi Z, Lemonas P, Myers S, Philpott MP, Navsaria H (2013). Matrix metalloproteinases 1, 2, 13 and 14 are differentially expressed in keloid scars compared to normal skin. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S250-S250.
Upton JH, Bahta A, Farjo N, Farjo B, Bhogal R, Philpott MP (2013). Oxidative stress and cell senescence in androgenetic alopecia (AGA). JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, 1398-1398.
Robles V, Philpott M, Navsaria H (2013). Tissue engineering a 3-D functional model of the human eccrine sweat gland. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S77-S77.
Brocklehurst K, Philpott MP(2013). Cysteine proteases: mode of action and role in epidermal differentiation. Cell Tissue Res vol. 351, (2) 237-244.
10.1007/s00441-013-1557-2
Patel II, Harrison WJ, Kerns JG, Filik J, Wehbe K, Carmichael PL, Scott AD, Philpott MP et al.(2012). Isolating stem cells in the inter-follicular epidermis employing synchrotron radiation-based Fourier-transform infrared microspectroscopy and focal plane array imaging. ANALYTICAL AND BIOANALYTICAL CHEMISTRY vol. 404, (6-7) 1745-1758.
10.1007/s00216-012-6314-y
Hannen R, Rajpopat S, Cerio R, Burrin J, Philpott M (2012). Downregulation of the Intracrine Skin Glucocorticoid Pathway in Psoriasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S53-S53.
Herath D, Rahman M, Mancuso M, Panagou L, Atkar R, Pirzado M, Saran A, Harwood C et al. (2012). Epidermal growth factor receptor signalling in basal cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e24-e24.
Rahman M, Herath D, Selway J, Roy A, Nadendla S, Kelsell D, Harwood C, Philpott M et al. (2012). In vitro modelling of basal cell carcinoma reveals a novel PTCH1-GLI1 signalling axis that is unresponsive to Smoothened inhibitors in human keratinocytes. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e29-e29.
Chikh A, Matin RNH, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M et al.(2011). iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia. EMBO J vol. 30, (20) 4261-4273.
10.1038/emboj.2011.302
Ramot Y, Tiede S, Biro T, Abu Bakar MH, Sugawara K, Philpott MP, Harrison W, Pietila M et al.(2011). Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions. PLOS ONE vol. 6, (7) Article e22564,
10.1371/journal.pone.0022564
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5408
Rahman MM, Kelsell DP, Philpott MP, Neill GW (2011). In vitro modelling of basal cell carcinoma reveals a novel PTCH1-GLI1 signalling axis that is independent of SMOOTHENED in human keratinocytes. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 907-908.
Pirzado MS, Rahman MM, Cerio R, Neill GW, Philpott MP (2011). Senescence in human basal cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 935-936.
Herath D, Rahman MM, Panagou L, Pirzado M, Harwood C, Philpott MP, Neill GW (2011). The tumour suppressor PTCH1 regulates EGFR signalling in human keratinocytes: implications for the treatment of basal cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 934-934.
Ruge F, Glavini A, Gallimore AM, Richards HE, Thomas CP, O'Donnell VB, Philpott MP, Porter RM(2011). Delineating Immune-Mediated Mechanisms Underlying Hair Follicle Destruction in the Mouse Mutant Defolliculated. J INVEST DERMATOL vol. 131, (3) 572-579.
10.1038/jid.2010.379
Hannen RF, Michael AE, Jaulim A, Bhogal R, Burrin JM, Philpott MP(2011). Steroid synthesis by primary human keratinocytes; implications for skin disease. Biochem Biophys Res Commun vol. 404, (1) 62-67.
10.1016/j.bbrc.2010.11.059
Nadendla SK, Hazan A, Ward M, Harper LJ, Moutasim K, Bianchi LS, Naase M, Ghali L et al.(2011). GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state. PLoS One vol. 6, (5)
10.1371/journal.pone.0020271
https://qmro.qmul.ac.uk/xmlui/handle/123456789/4859
Sully K, Akinduro OA, Philpott MP, Harwood CA, O'Shaughnessy RF, Byrne C (2011). Rapamycin treatment increases mTORC2 activity and selectively activates the AKT1 isoform in epidermis by inhibition of the mTORC1-dependent feedback loop to IRS-1. MOLECULAR BIOLOGY OF THE CELL. vol. 22,
Bahta AW, Farjo N, Farjo B, Philpott MP (2010). Expression of p16INK4 alpha in balding scalp hair follicles suggests an increased susceptibility to premature senescence and a possible mechanism of androgenetic alopecia Hormones, Hair Growth and Pattern Hair Loss. EXPERIMENTAL DERMATOLOGY. vol. 19, 571-571.
Upton JH, Bahta A, Farjo N, Farjo B, Philpott MP (2010). Senescence of male balding dermal papilla cells is associated with oxidative stress Hormones, Hair Growth and Pattern Hair Loss. EXPERIMENTAL DERMATOLOGY. vol. 19, 570-570.
Pantazi E, Trigiante G, Warnes G, Gemenetzidis E, Teh MT, Ikram M, Shan L, Lu YJ et al. (2010). Overexpression of GLI2 in human keratinocytes results in resistance to ultraviolet B-induced apoptosis and increased chromosomal instability. BRITISH JOURNAL OF DERMATOLOGY. vol. 162, 948-948.
Singh M, Breuer J, Heseltine R, Cerio R, Millar J, Philpott MP, O'Toole EA (2010). Varicella-zoster replication and its association with keratin 15 expression and Wnt signalling. BRITISH JOURNAL OF DERMATOLOGY. vol. 162, 914-915.
Teh M-T, Gemenetzidis E, Chaplin T, Young BD, Philpott MP(2010). Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes. Mol Cancer vol. 9,
10.1186/1476-4598-9-45
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7822
Al-Nuaimi Y, Kloepper JE, Philpott M, Toth BI, Watson RE, Gaspar E, Tiede S, Biro T et al. (2010). Two chronobiological systems meet: Genes, proteins and microRNAs central to circadian rhythm control are differentially regulated during cyclic human hair follicle cycling. EXPERIMENTAL DERMATOLOGY. vol. 19, 216-216.
Al-Nuaimi Y, Philpott M, Kloepper J, Toth B, McKay I, Biro T, Paus R (2009). A role for clock-related genes in human hair growth control?. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 129, S67-S67.
Gore SM, Kasper M, Williams T, Regl G, Aberger F, Cerio R, Neill GW, Philpott MP(2009). Neuronal differentiation in basal cell carcinoma: possible relationship to Hedgehog pathway activation?. J Pathol vol. 219, (1) 61-68.
10.1002/path.2568
Bianchi L, Philpott MP, Neill W (2009). A potential paracrine mode of hedgehog signalling in basal cell carcinoma development. BRITISH JOURNAL OF DERMATOLOGY. vol. 160, 926-927.
Elliott JA, Navsaria H, Philpott MP (2009). Modelling of basal cell carcinoma: culture and investigation of basal cell carcinoma-derived fibroblasts. BRITISH JOURNAL OF DERMATOLOGY. vol. 160, 926-926.
Ruge F, Glavini A, Philpott MP, Porter RM (2009). Mutations in gasdermin suggest paracrine control of PPAR gamma is responsible for maintaining sebaceous gland differentiation. BRITISH JOURNAL OF DERMATOLOGY. vol. 160, 922-923.
Pantazi E, Trigianti G, Warnes G, Gemenetzidis E, Teh MT, Philpott MP (2009). Overexpression of GLI2 in human keratinocytes results in polyploidy and resistance to ultraviolet B-induced apoptosis. BRITISH JOURNAL OF DERMATOLOGY. vol. 160, 908-908.
Singh M, Breuer J, Heseltine R, Millar J, Philpott MP, O'Toole EA (2009). Varicella-zoster virus infection in skin shows prominent involvement of adnexal stem cell compartments. BRITISH JOURNAL OF DERMATOLOGY. vol. 160, 904-904.
Roosen GF, Westgate GE, Philpott M, Berretty PJM, Nuijs T(2008). Temporary hair removal by low fluence photoepilation: Histological study on biopsies and cultured human hair follicles. LASER SURG MED vol. 40, (8) 520-528.
10.1002/lsm.20679
Bahta AW, Farjo N, Farjo B, Philpott MP(2008). Premature senescence of balding dermal papilla cells in vitro is associated with p16(INK4a) expression. J Invest Dermatol vol. 128, (5) 1088-1094.
10.1038/sj.jid.5701147
Hannen RF, Michael AE, Burrin J, Philpott M (2008). Cortisol synthesis and regulation of proliferation in keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 128, S139-S139.
Bahta AW, Farjo N, Farjo B, Philpott MP (2008). Effect of oxygen on premature senescence of balding dermal papilla cells in vitro identifies oxidative stress as a potential mechanism of androgenetic alopecia. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 128, S149-S149.
Williams TD, Ikram MS, Harrison WJ, Bianchi LS, Philpott MP, Neill GW (2008). GLI1 induces characteristics of a senescent response in N/Tert-1 keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 128, S33-S33.
Neill GW, Harrison WJ, Ikram MS, Williams TDL, Bianchi LS, Nadendla SK, Green JL, Ghali L et al.(2008). GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes. Carcinogenesis vol. 29, (4) 738-746.
10.1093/carcin/bgn037
Neill GW, Harrison W, Ikram M, Williams T, Bianchi L, Nadendla S, O'Toole EA, Aberger F et al. (2008). GLI1 repression of epidermal growth factor receptor extracellular signal-regulated kinase signalling may account for the poor metastatic potential of basal cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 158, 884-884.
Singh M, Breuer J, Cerio R, Millar J, Philpott MP, O'Toole EA (2008). Immunohistochemical study of varicella-zoster virus infection in skin confirms prominent involvement of the follicular epithelium. BRITISH JOURNAL OF DERMATOLOGY. vol. 158, 892-892.
Russell LE, Tropel P, Philpott MP, Navsaria H (2008). Mesenchymal control on keratinocyte phenotype. BRITISH JOURNAL OF DERMATOLOGY. vol. 158, 903-903.
Bahta AW, Farjo N, Farjo B, Philpott MP (2008). Premature senescence of balding dermal papilla cells in vitro is associated with p16(INK4a) expression and identifies environmental stress as a potential mechanism of androgenetic alopecia. BRITISH JOURNAL OF DERMATOLOGY. vol. 158, 880-880.
Hannen RF, Michael AE, Burrin J, Philpott MP (2008). StAR role for glucocorticoid synthesis in keratinocytes. BRITISH JOURNAL OF DERMATOLOGY. vol. 158, 881-881.
Singh M, Breuer J, Cerio R, Millar J, Philpott MP, O'Toole EA (2008). Varicella zoster virus colocalizes within adnexal stem cell compartments of skin. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 128, S194-S194.
Kloepper JE, Hendrix S, Bodó E, Tiede S, Humphries MJ, Philpott MP, Fässler R, Paus R(2008). Functional role of beta 1 integrin-mediated signalling in the human hair follicle. Exp Cell Res vol. 314, (3) 498-508.
10.1016/j.yexcr.2007.10.030
Neill W, Harrison WJ, Ikram MS, Williams TDL, Green JL, Ghali L, Frischauf AM, O'Toole EA et al. (2007). Attenuation of EGFR-ERK signalling by GLI1 highlights a mechanism to promote the epithelial phenotype and may account for the poor metastatic potential of basal cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 127, S91-S91.
Russell LE, Harrison WJ, Bahta AW, Zouboulis CC, Burrin JM, Philpott MP(2007). Characterization of liver X receptor expression and function in human skin and the pilosebaceous unit. Exp Dermatol vol. 16, (10) 844-852.
10.1111/j.1600-0625.2007.00612.x
Hannen RF, Michael AE, Burrin JM, Philpott M (2007). Human skin and keratinocytes express cholesterol transporters and primary keratinocytes are capable of metabolising progesterone into cortisol. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 127, S60-S60.
Williams TDL, Harrison WJ, Ikram MS, Philpott M, Neill W (2007). The oncogenic GLI (GLI1 and GLI2) transcription factors induce characteristics of cellular senescence in N/Tert-1 keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 127, S92-S92.
Harrison WJ, Bull JJ, Seltmann H, Zouboulis CC, Philpott MP(2007). Expression of lipogenic factors galectin-12, resistin, SREBP-1, and SCD in human sebaceous glands and cultured sebocytes. J Invest Dermatol vol. 127, (6) 1309-1317.
10.1038/sj.jid.5700743
Blaydon DC, Philpott MP, Kelsell DP(2007). R-spondins in cutaneous biology: Nails and cancer. Cell Cycle vol. 6, (8) 895-897.
10.4161/cc.6.8.4136
Blaydon DC, Philpott MP, Kelsell DP(2007). R-spondins in cutaneous biology: nails and cancer. Cell Cycle vol. 6, (8) 895-897.
10.4161/cc.6.8.4136
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Bull JJ, Pelengaris S, Hendrix S, Chronnell CMT, Khan M, Philpott MP(2005). Ectopic expression of c-Myc in the skin affects the hair growth cycle and causes an enlargement of the sebaceous gland. Br J Dermatol vol. 152, (6) 1125-1133.
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Blaydon DC, Teh M, Foot NJ, Philpott MP, Harwood C, Proby C, Young BD, Kelsell DP (2005). Genome-wide SNP microarray mapping in basal cell carcinomas unveils uniparental dismay as a key somatic event. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 124, A20-A20.
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Harrison WJ, Bull JJ, Zouboulis CC, Philpott MP (2005). The expression of early markers of adipocyte differentiation in sebaceous gland cells. BRITISH JOURNAL OF DERMATOLOGY. vol. 152, 856-856.
Philpott M(2005). What is the pathogenesis of acne? Commentary 1. EXP DERMATOL vol. 14, (2) 150-150.
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Neill GW, Ghali LR, Green JL, Ikram MS, Philpott MP, Quinn AG(2003). Loss of protein kinase Calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma. Cancer Res vol. 63, (15) 4692-4697.
Randall VA, Sundberg JP, Philpott MP (2003). Animal and in vitro models for the study of hair follicles. J Investig Dermatol Symp Proc. vol. 8, 39-45.
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Müller FB, Müller-Röver S, Korge BP, Kapas S, Hinson JP, Philpott MP(2003). Adrenomedullin: expression and possible role in human skin and hair growth. Br J Dermatol vol. 148, (1) 30-38.
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Neill GW, Green JL, Philpott MP, Quinn AG(2002). Differential regulation of Gli1 activity by PKC isoforms. J INVEST DERMATOL vol. 119, (1) 276-276.
Bull JJ, Müller-Röver S, Chronnell CMT, Paus R, Philpott MP, McKay IA(2002). Contrasting expression patterns of CCAAT/enhancer-binding protein transcription factors in the hair follicle and at different stages of the hair growth cycle. J Invest Dermatol vol. 118, (1) 17-24.
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Chronnell CM, Ghali LR, Ali RS, Quinn AG, Holland DB, Bull JJ, Cunliffe WJ, McKay IA et al.(2001). Human beta defensin-1 and -2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions. J Invest Dermatol vol. 117, (5) 1120-1125.
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Fletcher ST, Fentem JH, Basketter DA, Kelsell DP, Philpott M, Baker VA(2001). Microarray and proteomic analysis of early gene regulation following exposure to skin irritants. TOXICOLOGY vol. 168, (1) 101-102.
Mueller-Roever S, Beckley C, Philpott M, Paus R(2001). Integrin expression is hair cycle-dependent, and integrin blockers stimulate human hair growth in vitro. J INVEST DERMATOL vol. 117, (2) 396-396.
Bull JJ, Müller-Röver S, Patel SV, Chronnell CM, McKay IA, Philpott MP(2001). Contrasting localization of c-Myc with other Myc superfamily transcription factors in the human hair follicle and during the hair growth cycle. J Invest Dermatol vol. 116, (4) 617-622.
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Philpott MP, Kealey T(2000). Cyclical changes in rat vibrissa follicles maintained in vitro. J INVEST DERMATOL vol. 115, (6) 1152-1155.
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