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Publications:  Prof Sussan Nourshargh

Owen-Woods C, Joulia R, Barkaway A, Rolas L, Ma B, Nottebaum FA, Arkill KP, Stein M et al.(2020). Local microvascular leakage promotes trafficking of activated neutrophils to remote organs. Journal of Clinical Investigation
Arokiasamy S, King R, Boulaghrasse H, Poston R, Nourshargh S, Wang W, Voisin M-B(2019). Heparanase-dependent Remodelling of Initial Lymphatic Glycocalyx 1 Regulates Tissue-fluid Drainage during Acute Inflammation in vivo. Frontiers in Immunology
Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N et al.(2019). Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology vol. 49, (10) 1457-1973.
Voisin M-B, Nourshargh S(2019). Neutrophil trafficking to lymphoid tissues: physiological and pathological implications. J Pathol vol. 247, (5) 662-671.
VOISIN M, leoni G, WOODFIN A, loumagne L, PATEL N, Di Paola R, Cuzzocrea S, THIEMERMANN C et al.(2019). Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post ischemia/reperfusion injury. Journal of Pathology vol. 248, (1) 88-102.
Reglero-Real N, Rolas L, Nourshargh S(2019). Leukocyte Trafficking: Time to Take Time Seriously. Immunity vol. 50, (2) 273-275.
NOURSHARGH S, ROLAS L, BARKAWAY A(2019). Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome. Nature Medicine423-426.
Kostelnik KB, Barker A, Schultz C, Mitchell TP, Rajeeve V, White IJ, Aurrand-Lions M, Nourshargh S et al.(2019). Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration. PLoS Biology vol. 17, (12)
GIRBL T, Lenn T, Perez L, ROLAS L, BARKAWAY A, Thiriot A, del Fresno C, Lynam E et al.(2018). Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis. Immunity
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2018). Correction: Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Med vol. 15, (10) e1002694-e1002694.
Cossarizza A, Chang H-D, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V et al.(2018). Guidelines for the use of flow cytometry and cell sorting in immunological studies. Eur J Immunol vol. 47, (10) 1584-1797.
Wen G, An W, Chen J, Maguire EM, Chen Q, Yang F, Pearce SWA, Kyriakides M et al.(2018). Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. J Am Heart Assoc vol. 7, (4)
Schulz-Fincke A-C, Tikhomirov AS, Braune A, Girbl T, Gilberg E, Bajorath J, Blaut M, Nourshargh S et al.(2018). Design of an Activity-Based Probe for Human Neutrophil Elastase: Implementation of the Lossen Rearrangement To Induce Förster Resonance Energy Transfers. Biochemistry vol. 57, (5) 742-752.
Callender LA, carroll EC, beal R, Chambers ES, Nourshargh S, Akbar AN, Henson SM(2017). Human CD8+ EMRA T cells display a senescent-associated secretory phenotype regulated by p38 MAPK. Aging Cell
CABRERA CP, MANSON J, SHEPHERD JM, TORRANCE HD, WATSON D, LONGHI MP, HOTI M, PATEL MB et al.(2017). Signatures of Inflammation and Impending Multiple Organ Dysfunction in the Hyperacute Phase of Trauma. PLoS Medicine
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2017). Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Medicine vol. 14, (7)
Gittens BR, Bodkin JV, Nourshargh S, Perretti M, Cooper D(2017). Galectin-3: A positive regulator of leukocyte recruitment in the inflamed microcirculation. Journal of Immunology vol. 198, (11) 4458-4469.
VOISIN M(2017). Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation. Scientific Reports
Barzilai S, Yadav SK, Morrell S, Roncato F, Klein E, Stoler-Barak L, Golani O, Feigelson SW et al.(2017). Leukocytes Breach Endothelial Barriers by Insertion of Nuclear Lobes and Disassembly of Endothelial Actin Filaments. Cell Rep vol. 18, (3) 685-699.
Herrera C, Voisin M-B, Escalante T, Rucavado A, Nourshargh S, Gutiérrez JM(2016). Effects of PI and PIII Snake Venom Haemorrhagic Metalloproteinases on the Microvasculature: A Confocal Microscopy Study on the Mouse Cremaster Muscle. PLoS One vol. 11, (12) Article 0168643, e0168643-e0168643.
Reglero-Real N, Colom B, Bodkin JV, Nourshargh S(2016). Endothelial Cell Junctional Adhesion Molecules. Arteriosclerosis, Thrombosis and Vascular BiologyATVBAHA.116.307610-ATVBAHA.116.307610.
WHITEFORD J, Ma B, Woodfin, Nourshargh(2016). Underlying chronic inflammation alters the profile and mechanisms of acute neutrophil recruitment. Journal of Pathology
Nourshargh S, Renshaw SA, Imhof BA(2016). Reverse Migration of Neutrophils: Where, When, How, and Why?. Trends in immunology
Woodfin A, Beyrau M, Voisin M-B, Ma B, Whiteford JR, Hordijk PL, Hogg N, Nourshargh S(2016). ICAM-1-expressing neutrophils exhibit enhanced effector functions in murine models of endotoxemia. Blood vol. 127, (7) 898-907.
Madalli S, Beyrau M, Whiteford J, Duchene J, Nandhra IS, Patel NSA, Motwani MP, Gilroy DW et al.(2015). Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states. Biology of Sex Differences vol. 6, (1)
Yeh JSM, Sennoga CA, McConnell E, Eckersley R, Tang MX, Nourshargh S, Seddon JM, Haskard DO et al.(2015). Quantitative Ultrasound Molecular Imaging. Ultrasound in Medicine and Biology vol. 41, (9) 2478-2496.
Armstrong PCJ, Kirkby NS, Chan MV, Finsterbusch M, Hogg N, Nourshargh S, Warner TD(2015). Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction. Blood vol. 126, (10) e11-e18.
Yeh JSM, Sennoga CA, McConnell E, Eckersley R, Tang MX, Nourshargh S, Seddon JM, Haskard DO et al.(2015). A targeting microbubble for ultrasound molecular imaging. PLoS ONE vol. 10, (7)
Colom B, Bodkin JV, Beyrau M, Woodfin A, Ody C, Rourke C, Chavakis T, Brohi K et al.(2015). Leukotriene B<inf>4</inf>-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration InVivo. Immunity vol. 42, (6) 1075-1086.
Herrera C, Escalante T, Voisin M-B, Rucavado A, Morazán D, Macêdo JKA, Calvete JJ, Sanz L et al.(2015). Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage. PLoS Negl Trop Dis vol. 9, (4)
Nourshargh S, Alon R(2014). Leukocyte migration into inflamed tissues. Immunity vol. 41, (5) 694-707.
De Rossi G, Evans AR, Kay E, Woodfin A, McKay TR, Nourshargh S, Whiteford JR(2014). Shed syndecan-2 inhibits angiogenesis. J Cell Sci vol. 127, (Pt 21) 4788-4799.
Finsterbusch M, Voisin M-B, Beyrau M, Williams TJ, Nourshargh S(2014). Neutrophils recruited by chemoattractants in vivo induce microvascular plasma protein leakage through secretion of TNF. J Exp Med vol. 211, (7) 1307-1314.
Colom B, Bodkin JV, Beyrau M, Woodfin A, Ody C, Rourke C, Chavakis T, Brohi K et al.(2014). Leukotriene B<inf>4</inf>-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration InVivo. Immunity
Halai K, Whiteford J, Ma B, Nourshargh S, Woodfin A(2014). ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo. J Cell Sci vol. 127, (Pt 3) 620-629.
Leinster DA, Colom B, Whiteford JR, Ennis DP, Lockley M, McNeish IA, Aurrand-Lions M, Chavakis T et al.(2013). Endothelial cell junctional adhesion molecule C plays a key role in the development of tumors in a murine model of ovarian cancer. FASEB J vol. 27, (10) 4244-4253.
Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S et al.(2013). A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood vol. 122, (4) 608-617.
Alazawi W, Heath H, Waters JA, Woodfin A, O'Brien AJ, Scarzello AJ, Ma B, Lopez-Otalora Y et al.(2013). Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis. Proc Natl Acad Sci U S A vol. 110, (21) 8656-8661.
Nourshargh S(2013). L2. Neutrophil transmigration in vivo: mechanisms, dynamics and contribution to dissemination of systemic inflammation. Presse Med vol. 42, (4 Pt 2) 498-499.
Alon R, Nourshargh S(2013). Learning in motion: pericytes instruct migrating innate leukocytes. Nat Immunol vol. 14, (1) 14-15.
Voisin M-B, Nourshargh S(2013). Neutrophil transmigration: emergence of an adhesive cascade within venular walls. J Innate Immun vol. 5, (4) 336-347.
Kishore M, Ma L, Cornish G, Nourshargh S, Marelli-Berg F (2012). Primed T Cell Responses to Chemokines Are Regulated by the Immunoglobulin-Like Molecule CD31. TRANSPLANTATION. vol. 94, 456-456.
Beyrau M, Bodkin JV, Nourshargh S(2012). Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity. Open Biol vol. 2, (11)
Ma L, Cheung KCP, Kishore M, Nourshargh S, Mauro C, Marelli-Berg FM(2012). CD31 exhibits multiple roles in regulating T lymphocyte trafficking in vivo. J Immunol vol. 189, (8) 4104-4111.
Avari P, Huang W, Averill S, Colom B, Imhof BA, Nourshargh S, Priestley JV(2012). The spatiotemporal localization of JAM-C following sciatic nerve crush in adult rats. Brain Behav vol. 2, (4) 402-414.
Proebstl D, Voisin M-B, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S(2012). Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med vol. 209, (6) 1219-1234.
Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D et al.(2012). The peritoneal tumour microenvironment of high-grade serous ovarian cancer. J Pathol vol. 227, (2) 136-145.
Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD et al.(2012). Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. FASEB J vol. 26, (3) 1064-1076.
Kishore M, Ma L, Cornish G, Nourshargh S, Marelli-Berg FM(2012). Primed T cell responses to chemokines are regulated by the immunoglobulin-like molecule CD31. PLoS One vol. 7, (6)
Whiteford JR, Xian X, Chaussade C, Vanhaesebroeck B, Nourshargh S, Couchman JR(2011). Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148. Mol Biol Cell vol. 22, (19) 3609-3624.
Woodfin A, Voisin M-B, Beyrau M, Colom B, Caille D, Diapouli F-M, Nash GB, Chavakis T et al.(2011). The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo. Nat Immunol vol. 12, (8) 761-769.
Veninga H, de Groot DM, McCloskey N, Owens BM, Dessing MC, Verbeek JS, Nourshargh S, van Eenennaam H et al.(2011). CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism. J Leukoc Biol vol. 89, (3) 413-421.
Ma L, Mauro C, Cornish GH, Chai J-G, Coe D, Fu H, Patton D, Okkenhaug K et al.(2010). Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance. Proc Natl Acad Sci U S A vol. 107, (45) 19461-19466.
Nourshargh S, Hordijk PL, Sixt M(2010). Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat Rev Mol Cell Biol vol. 11, (5) 366-378.
Leoni G, Voisin M-B, Carlson K, Getting S, Nourshargh S, Perretti M(2010). The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature. Br J Pharmacol vol. 160, (1) 171-180.
Woodfin A, Voisin M-B, Nourshargh S(2010). Recent developments and complexities in neutrophil transmigration. Curr Opin Hematol vol. 17, (1) 9-17.
Voisin M-B, Pröbstl D, Nourshargh S(2010). Venular basement membranes ubiquitously express matrix protein low-expression regions: characterization in multiple tissues and remodeling during inflammation. Am J Pathol vol. 176, (1) 482-495.
Scheiermann C, Colom B, Meda P, Patel NSA, Voisin M-B, Marrelli A, Woodfin A, Pitzalis C et al.(2009). Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler Thromb Vasc Biol vol. 29, (10) 1509-1515.
Voisin M-B, Woodfin A, Nourshargh S(2009). Monocytes and neutrophils exhibit both distinct and common mechanisms in penetrating the vascular basement membrane in vivo. Arterioscler Thromb Vasc Biol vol. 29, (8) 1193-1199.
Woodfin A, Voisin MB, Imhof BA, Dejana E, Engelhardt B, Nourshargh S(2009). Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. BLOOD vol. 113, (24) 6246-6257.
Woodfin A, Voisin M-B, Imhof BA, Dejana E, Engelhardt B, Nourshargh S(2009). Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood vol. 113, (24) 6246-6257.
Little MA, Smyth L, Salama AD, Mukherjee S, Smith J, Haskard D, Nourshargh S, Cook HT et al.(2009). Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis. Am J Pathol vol. 174, (4) 1212-1220.
Woodfin A, Voisin M-B, Nourshargh S(2007). PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler Thromb Vasc Biol vol. 27, (12) 2514-2523.
Scheiermann C, Meda P, Aurrand-Lions M, Madani R, Yiangou Y, Coffey P, Salt TE, Ducrest-Gay D et al.(2007). Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves. Science vol. 318, (5855) 1472-1475.
Bradfield PF, Nourshargh S, Aurrand-Lions M, Imhof BA(2007). JAM family and related proteins in leukocyte migration (Vestweber series). Arterioscler Thromb Vasc Biol vol. 27, (10) 2104-2112.
Bradfield PF, Scheiermann C, Nourshargh S, Ody C, Luscinskas FW, Rainger GE, Nash GB, Miljkovic-Licina M et al.(2007). JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood vol. 110, (7) 2545-2555.
Woodfin A, Reichel CA, Khandoga A, Corada M, Voisin M-B, Scheiermann C, Haskard DO, Dejana E et al.(2007). JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration. Blood vol. 110, (6) 1848-1856.
Ley K, Laudanna C, Cybulsky MI, Nourshargh S(2007). Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol vol. 7, (9) 678-689.
NOURSHARGH S, Krombach F, Dejana E, Khandoga A, Woodfin A, Reichal AC, Haskard DO, Scheiermann C et al.(2007). JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: Evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration. Blood vol. 110, (6) 1848-1856.
Young RE, Voisin M-B, Wang S, Dangerfield J, Nourshargh S(2007). Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice. Br J Pharmacol vol. 151, (5) 628-637.
Voisin MB, Woodfin A, Nourshargh S (2007). Neutrophil and monocyte transmigration elicited by ischemia/reperfusion (I/R) injury and CCL2 is associated with remodelling of the venular basement membrane (BM) in vivo. FASEB JOURNAL. vol. 21, A127-A127.
Woodfin A, Larbi K, Krombach F, Dejana E, Nourshargh S (2007). PECAM-1 & JAM-A mediate leukocyte transmigration in a stimulus-specific manner: Is this phenomenon governed by the strain of mice investigated?. FASEB JOURNAL. vol. 21, A127-A127.
Potter PK, Larbi KY, Nourshargh S, Botto M(2007). Efficient clearance of opsonised apoptotic cells in the absence of PECAM-1. Mol Immunol vol. 44, (6) 1135-1140.
Nourshargh S, Krombach F, Dejana E(2006). The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues. J Leukoc Biol vol. 80, (4) 714-718.
Huang M-T, Larbi KY, Scheiermann C, Woodfin A, Gerwin N, Haskard DO, Nourshargh S(2006). ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration. Blood vol. 107, (12) 4721-4727.
Wang S, Voisin M-B, Larbi KY, Dangerfield J, Scheiermann C, Tran M, Maxwell PH, Sorokin L et al.(2006). Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils. J Exp Med vol. 203, (6) 1519-1532.
Woodfin A, Reichel C, Khandoga A, Corada M, Haskard D, Dejana E, Krombach F, Nourshargh S (2006). JAM-A mediates leukocyte transmigration in a stimulus-specific manner. FASEB JOURNAL. vol. 20, A862-A862.
Voisin MB, Woodfin A, Dawes T, Nourshargh S (2006). Neutrophil elastase (NE) deficient mice exhibit reduced leukocyte transmigration in response to ischaemia/reperfusion (I/R) injury. FASEB JOURNAL. vol. 20, A1083-A1083.
Voisin MB, Wang SJ, Larbi K, Scheiermann C, Sorokin L, Nourshargh S (2006). Neutrophils play a direct role in enhancing the size of venular basement membrane (BM) matrix protein low expression regions. FASEB JOURNAL. vol. 20, A1322-A1322.
Tharp WG, Yadav R, Irimia D, Upadhyaya A, Samadani A, Hurtado O, Liu S-Y, Munisamy S et al.(2006). Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo. J Leukoc Biol vol. 79, (3) 539-554.
Reichel CA, Khandoga A, Woodfin A, Corada M, Dejana E, Nourshargh S, Krombach F (2006). JAM-A mediates leukocyte transmigration dynamically and in a stimulus-specific manner. JOURNAL OF VASCULAR RESEARCH. vol. 43, 576-576.
Little MA, Bhangal G, Smyth CL, Nakada MT, Cook HT, Nourshargh S, Pusey CD (2006). Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis. J Am Soc Nephrol. vol. 17, 160-169.
Ambrose LR, Little MA, Nourshargh S, Pusey CD(2005). Anti-proteinase 3 antibody binding to neutrophils as demonstrated by confocal microscopy. Kidney Int vol. 68, (6) 2912-2913.
Little MA, Pusey CD, Nourshargh S (2005). Intravital microscopy in the study of ANCA-associated systemic vasculitis. Clin Nephrol. vol. 64, 465-470.
Little MA, Smyth CL, Yadav R, Ambrose L, Cook HT, Nourshargh S, Pusey CD(2005). Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo. Blood vol. 106, (6) 2050-2058.
Chatterjee BE, Yona S, Rosignoli G, Young RE, Nourshargh S, Flower RJ, Perretti M(2005). Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro. J Leukoc Biol vol. 78, (3) 639-646.
Aurrand-Lions M, Lamagna C, Dangerfield JP, Wang S, Herrera P, Nourshargh S, Imhof BA(2005). Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation. J Immunol vol. 174, (10) 6406-6415.
Wang S, Dangerfield JP, Young RE, Nourshargh S(2005). PECAM-1, alpha6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration. J Cell Sci vol. 118, (Pt 9) 2067-2076.
Huang MT, Larbi KY, Gerwin N, Nourshargh S (2005). ICAM-2 mediates PECAM-1-independent neutrophil transmigration in vivo. FASEB JOURNAL. vol. 19, A1504-A1505.
Voisin MB, Young R, Dangerfield J, Wijayasiri L, Wang SJ, Nourshargh S (2005). LTB4 is a potent inducer of cell surface neutrophil elastase (NE), a response that appears to play a role in LTB4-induced neutrophil transmigration in vivo. FASEB JOURNAL. vol. 19, A1717-A1717.
Wang SJ, Dangerfield J, Voisin MB, Tran M, Maxwell P, Sorokin L, Nourshargh S (2005). Pre-formed matrix protein "low expression" regions act as exit points for leukocytes migrating through the venular perivascular basement membrane. FASEB JOURNAL. vol. 19, A1504-A1504.
Nourshargh S, Marelli-Berg FM(2005). Transmigration through venular walls: a key regulator of leukocyte phenotype and function. Trends Immunol vol. 26, (3) 157-165.
Dangerfield JP, Wang S, Nourshargh S(2005). Blockade of alpha6 integrin inhibits IL-1beta- but not TNF-alpha-induced neutrophil transmigration in vivo. J Leukoc Biol vol. 77, (2) 159-165.
Marelli-Berg FM, James MJ, Dangerfield J, Dyson J, Millrain M, Scott D, Simpson E, Nourshargh S et al.(2004). Cognate recognition of the endothelium induces HY-specific CD8+ T-lymphocyte transendothelial migration (diapedesis) in vivo. Blood vol. 103, (8) 3111-3116.
Young RE, Thompson RD, Larbi KY, La M, Roberts CE, Shapiro SD, Perretti M, Nourshargh S(2004). Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo. J Immunol vol. 172, (7) 4493-4502.
Norsworthy PJ, Fossati-Jimack L, Cortes-Hernandez J, Taylor PR, Bygrave AE, Thompson RD, Nourshargh S, Walport MJ et al.(2004). Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J Immunol vol. 172, (6) 3406-3414.
McMillan SJ, Kearley J, Campbell JD, Zhu X-W, Larbi KY, Shipley JM, Senior RM, Nourshargh S et al.(2004). Matrix metalloproteinase-9 deficiency results in enhanced allergen-induced airway inflammation. J Immunol vol. 172, (4) 2586-2594.
Yadav R, Larbi KY, Young RE, Nourshargh S(2003). Migration of leukocytes through the vessel wall and beyond. THROMBOSIS AND HAEMOSTASIS vol. 90, (4) 598-606.
James MJ, Belaramani L, Prodromidou K, Datta A, Nourshargh S, Lombardi G, Dyson J, Scott D et al.(2003). Anergic T cells exert antigen-independent inhibition of cell-cell interactions via chemokine metabolism. Blood vol. 102, (6) 2173-2179.
Marshall D, Dangerfield JP, Bhatia VK, Larbi KY, Nourshargh S, Haskard DO(2003). MRL/lpr lupus-prone mice show exaggerated ICAM-1-dependent leucocyte adhesion and transendothelial migration in response to TNF-alpha. Rheumatology (Oxford) vol. 42, (8) 929-934.
Larbi KY, Dangerfield JP, Nourshargh S (2003). MMP-9 regulates eosinophil transmigration and expression of CCR3 on transmigrated eosinophils in vivo. FASEB JOURNAL. vol. 17, A1071-A1071.
Young RE, Thompson RD, Larbi KY, La M, Roberts C, Shapir SD, Perretti M, Nourshargh S (2003). Neutrophil elastase (NE) plays a non-redundant role in zymosan-induced leukocyte migration. FASEB JOURNAL. vol. 17, A1188-A1188.
Larbi KY, Dangerfield JP, Culley FJ, Marshall D, Haskard DO, Jose PJ, Williams TJ, Nourshargh S(2003). P-selectin mediates IL-13-induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL-4-elicited responses. J Leukoc Biol vol. 73, (1) 65-73.
Young RE, Thompson RD, Nourshargh S(2002). Divergent mechanisms of action of the inflammatory cytokines interleukin 1-beta and tumour necrosis factor-alpha in mouse cremasteric venules. Br J Pharmacol vol. 137, (8) 1237-1246.
Dangerfield J, Larbi KY, Huang M-T, Dewar A, Nourshargh S(2002). PECAM-1 (CD31) homophilic interaction up-regulates alpha6beta1 on transmigrated neutrophils in vivo and plays a functional role in the ability of alpha6 integrins to mediate leukocyte migration through the perivascular basement membrane. J Exp Med vol. 196, (9) 1201-1211.
Young RE, Thompson RD, Nourshargh S(2002). Divergent mechanisms of action of the inflammatory cytokines interleukin 1-beta (IL-1 beta) and factor-alpha (TNF alpha) in mouse cremasteric venules. BRIT J PHARMACOL vol. 135,
Thompson RD, Noble KE, Larbi KY, Dewar A, Duncan GS, Mak TW, Nourshargh S(2001). Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane. Blood vol. 97, (6) 1854-1860.
Marshall D, Bhatia VK, Ahmed S, Lidington EA, Larbi KY, Nourshargh S, Haskard DO(2001). Expression of P- but not E-selectin in peritoneal microvasculature during inflammatory peritonitis. FASEB J vol. 15, (4) A328-A328.
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