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Publications:  Prof Edel O'Toole

Maruthappu T, Posafalvi A, Castelletti S, Delaney PJ, Syrris P, O'Toole EA, Green KJ, Elliott PM et al.(2019). Loss-of-function desmoplakin I and II mutations underlie dominant arrhythmogenic cardiomyopathy with a hair and skin phenotype. British Journal of Dermatology vol. 180, (5) 1114-1122.
10.1111/bjd.17388
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49603
Bladen JC, Wang J, Sangaralingam A, Moosajee M, Fitchett C, Chelala C, Beaconsfield M, O'Toole EA et al.(2018). MicroRNA and transcriptome analysis in periocular Sebaceous Gland Carcinoma. Scientific Reports vol. 8, (1)
10.1038/s41598-018-25900-z
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44983
KELSELL DP, O'TOOLE E, PIGORS M, SCOTT CA, Tabarra N, VAN HEEL DA(2018). Exome sequencing and rare variant analysis reveals multiple filaggrin mutations in Bangladeshi atopic eczema families and novel risk genes. Journal of Investigative Dermatology
10.1016/j.jid.2018.05.013
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39403
Maruthappu T, McGinty LA, Blaydon DC, Fell B, Määttä A, Duit R, Hawkins T, Braun KM et al.(2018). Recessive Mutation in FAM83G Associated with Palmoplantar Keratoderma and Exuberant Scalp Hair. Journal of Investigative Dermatology vol. 138, (4) 984-987.
10.1016/j.jid.2017.10.031
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28664
Badowski C, Sim AYL, Verma C, Szeverényi I, Natesavelalar C, Terron-Kwiatkowski A, Harper J, O'Toole EA et al.(2017). Modeling the Structure of Keratin 1 and 10 Terminal Domains and their Misassembly in Keratoderma. J Invest Dermatol vol. 137, (9) 1914-1923.
10.1016/j.jid.2017.03.038
Kelsell DP, Rajpopat S, Thomas A, O'Toole EA (2016). Harlequin Ichthyosis: genetic, functional and clinical investigations. BRITISH JOURNAL OF DERMATOLOGY. vol. 175, 50-50.
O'Toole EA, Ruban EL, Balogun M, Martins VL, Caley MP, Falasca M (2016). Phospholipase C beta4 is a therapeutic target in cutaneous squamous cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 175, 56-57.
Posafalvi A, Maruthappu T, Castelletti S, Syrris P, O'Toole E, McKenna WJ, Kelsell DP (2016). Clinical and genetic studies reveal cutaneous phenotypes linked to desmoplakin haploinsufficiency in arrhythmogenic cardiomyopathy. vol. 136, is. 9, pp. S192-S192.
10.1016/j.jid.2016.06.201
McGeoghan F, Menon M, Dewan P, Caley M, Donaldson M, O'Toole EA (2016). Identification of novel pathways linked to the pathogenesis of Recessive X-Linked Ichthyosis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S183-S183.
10.1016/j.jid.2016.06.150
Caley M, Martins V, Moore K, Lashari M, Kahari V, Nissinen L, Donaldson M, Marshall J et al. (2016). Loss of Laminin alpha 3 drives SCC invasion via ROCK signalling. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S241-S241.
10.1016/j.jid.2016.06.494
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59408
Maruthappu T, McGinty L, Blaydon D, Duit R, Maatta A, O'Toole E, Kelsell DP (2016). Mutations in FAM83G/PAWS1 cause autosomal recessive palmoplantar keratoderma with leukonychia and abundant curly hair. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S191-S191.
10.1016/j.jid.2016.06.198
Enjalbert F, Dewan P, Caley M, Fell B, Donaldson M, Kelsell DP, O'Toole EA (2016). Understanding the role of ABCA12 in the pathogenesis of Harlequin Ichthyosis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S183-S183.
10.1016/j.jid.2016.06.151
Ahmed A, McGinty L, Blaydon D, Kelsell DP, O'Toole EA, De Silva B (2016). Mild arthrogryposis, renal dysfunction and cholestasis syndrome caused by a novel splice-site mutation in VPS33B. BRITISH JOURNAL OF DERMATOLOGY. vol. 175, 81-82.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16012
McDonald B, Amieva M, Kelsell DP, O'Toole EA, Burkett-Wright E, Kerr B, Batta K (2016). Noonan syndrome with multiple lentigines identified by next-generation sequencing. BRITISH JOURNAL OF DERMATOLOGY. vol. 175, 163-163.
Ziaj S, Pigors M, Scott C, Lewis F, Ali I, Roberts N, Kelsell DP, O'Toole EA (2016). Novel mutations in SLURP1 causing Mal de Meleda palmoplantar keratoderma with varying phenotypes. BRITISH JOURNAL OF DERMATOLOGY. vol. 175, 81-81.
Muttardi K, Nitoiu D, Kelsell DP, O'Toole EA, Batta K(2016). Acral peeling skin syndrome associated with a novel CSTA gene mutation. Clinical and Experimental Dermatology vol. 41, (4) 394-398.
10.1111/ced.12777
Badowski C, Sim AYL, Verma C, Szeverenyi I, Dang TT, Ng Y, Natesavelalar C, Benny P et al. (2016). A new model for the structure of the head domains of keratins K1 and K10 and its implications for striate palmoplantar keratoderma. BRITISH JOURNAL OF DERMATOLOGY. vol. 174, E45-E45.
Kenny F, Kao A, Barber A, O'Toole E, Connelly J (2016). Epidermal growth factor signalling mediates keratinocyte mechanoregulation. BRITISH JOURNAL OF DERMATOLOGY. vol. 174, E44-E44.
Pigors M, Common JE, Wong C, Malik S, Scott CA, Foo J, Liu J, Margolis D et al. (2016). Exome sequencing and rare variant analysis reveals multiple filaggrin mutations in Bangladeshi atopic eczema families and novel risk genes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S67-S67.
10.1016/j.jid.2016.02.413
Pigors M, Common JEA, Wong C, Scott CA, Foo JN, Liu J, O'Toole E, Simpson MA et al. (2016). Exome sequencing reveals multiple filaggrin mutations in Bangladeshi families with atopic eczema. BRITISH JOURNAL OF DERMATOLOGY. vol. 174, E64-E65.
McGeoghan FT, O'Toole E, Caley M, Menon M, Dewan P, Donaldson M (2016). Modelling and understanding pathomechanisms of X-linked recessive ichthyosis in vitro. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S66-S66.
10.1016/j.jid.2016.02.408
Chao L, Gor V, Murrell DF, Kim M, O'Toole E, Ly A, Woodley D, Wysong A et al. (2016). Over-expression of periostin is associated with clinical outcomes and poor prognosis in cutaneous squamous cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S75-S75.
10.1016/j.jid.2016.02.456
Caley M, Martins V, Moore K, Lashari M, Donaldson M, Marshall JF, O'Toole EA (2016). ROCK and Rac1 signalling in squamous cell carcinoma with loss of laminin 332. BRITISH JOURNAL OF DERMATOLOGY. vol. 174, E51-E51.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63939
Krupiczojc MA, O'Toole EA(2016). Management of cutaneous squamous cell carcinoma in patients with epidermolysis bullosa. Br J Dermatol vol. 174, (1)
10.1111/bjd.14339
Hill DS, Robinson NDP, Caley MP, Chen M, O'Toole EA, Armstrong JL, Przyborski S, Lovat PE(2015). A novel fully humanized 3D skin equivalent to model early melanoma invasion. Molecular Cancer Therapeutics vol. 14, (11) 2665-2673.
10.1158/1535-7163.MCT-15-0394
Wilson NJ, Cole C, Milstone LM, Kiszewski AE, Hansen CD, O'Toole EA, Schwartz ME, Irwin McLean WH et al.(2015). Expanding the Phenotypic Spectrum of Olmsted Syndrome. J Invest Dermatol vol. 135, (11) 2879-2883.
10.1038/jid.2015.217
Thomson J, O'Toole EA(2015). The future of U.K. dermatology translational research through the Oracle of Delphi. British Journal of Dermatology vol. 173, (5) 1122-1123.
10.1111/bjd.14194
Kopecki Z, Yang GN, Jackson JE, Melville EL, Calley MP, Murrell DF, Darby IA, O'Toole EA et al.(2015). Cytoskeletal protein Flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression. Oncotarget vol. 6, (34) 36426-36440.
10.18632/oncotarget.5536
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16231
Martins VL, Caley MP, Moore K, Szentpetery Z, Marsh ST, Murrell DF, Kim MH, Avari M et al.(2015). Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC. J Natl Cancer Inst vol. 108, (1)
10.1093/jnci/djv293
https://qmro.qmul.ac.uk/xmlui/handle/123456789/29087
Marsh S, Martins V, Caley M, Barnes M, Donaldson MJ, O'toole E (2015). Loss of keratinocyte type VII collagen induces pro-carcinogenic transcriptomic pathways. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S44-S44.
McGeoghan FT, Derwin P, Caley M, Donaldson MJ, O'toole E (2015). Modelling X-linked recessive ichthyosis in vitro. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S62-S62.
Martins V, Caley M, Moore K, Szentpetery Z, Marsh S, Murrell DF, Kaehaeri V, McGrath J et al. (2015). Skin type VII collagen acts as a tumour suppressor by regulating TGF beta and angiogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S28-S28.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10961
Caley M, Martins V, Marsh S, Moore K, Lashari M, Donaldson MJ, Marshall J, O'toole E (2015). Squamous Cell Carcinoma progression and Laminin 332. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S23-S23.
Chinthapalli S, Buckley D, Lin Z, Nitoiu D, Scott C, Smith F, Yang Y, Kelsell D et al. (2015). A novel peeling skin syndrome. BRITISH JOURNAL OF DERMATOLOGY. vol. 173, 78-78.
Knöbel M, O'Toole EA, Smith FJD(2015). Keratins and skin disease. Cell Tissue Res vol. 360, (3) 583-589.
10.1007/s00441-014-2105-4
Kenny F, Kao A, Barber A, O'Toole E, Connelly JT (2015). Epidermal growth factor signalling mediates mechanoregulation of keratinocyte proliferation. BRITISH JOURNAL OF DERMATOLOGY. vol. 172, E33-E33.
McGeoghan F, Dewan P, Caley M, Donaldson M, O'Toole E (2015). Generation of an in vitro three-dimensional model of X-linked recessive ichthyosis. BRITISH JOURNAL OF DERMATOLOGY. vol. 172, E40-E40.
Lin Z, Zhao J, Nitoiu D, Scott CA, Plagnol V, Smith FJD, Wilson NJ, Cole C et al.(2015). Loss-of-function mutations in CAST cause peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads. American Journal of Human Genetics vol. 96, (3) 440-447.
10.1016/j.ajhg.2014.12.026
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23763
O'Toole EA, Kaspar RL, Sprecher E, Schwartz ME, Rittié L(2014). Pachyonychia congenita cornered: report on the 11th Annual International Pachyonychia Congenita Consortium Meeting. Br J Dermatol vol. 171, (5) 974-977.
10.1111/bjd.13341
Brooke MA, O'Toole EA, Kelsell DP(2014). Exoming into rare skin disease: EGFR deficiency. J Invest Dermatol vol. 134, (10) 2486-2488.
10.1038/jid.2014.228
Caley M, Martins V, Moore K, Marshall J, O'toole E (2014). Diverse roles for laminin 332 subunits in squamous cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S19-S19.
Lin Z, Nitoiu D, Scott C, Zhao J, Plagnol V, O'toole E, Kelsell D, Yang Y (2014). Peeling skin, leukonychia, acral punctate keratoses, cheilitis and knuckle pads with milia caused by loss-of-function mutations in calpastatin. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S53-S53.
Ruban EL, Balogun MA, Martins V, Caley M, Raimondi C, O'toole E, Falasca M (2014). Phospholipase C beta4 regulates invasion and proliferation in cutaneous SCC in vivo. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S22-S22.
Marsh S, Martins V, Caley M, Barnes M, Donaldson M, O'toole E (2014). RNA-Seqing the skin basement membrane. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S25-S25.
Ahmed H, O'Toole EA(2014). Recent advances in the genetics and management of harlequin ichthyosis. Pediatr Dermatol vol. 31, (5) 539-546.
10.1111/pde.12383
Cicho¿ MA, Szentpetery Z, Caley MP, Papadakis ES, Mackenzie IC, Brennan CH, O'Toole EA(2014). The receptor tyrosine kinase Axl regulates cell-cell adhesion and stemness in cutaneous squamous cell carcinoma. Oncogene vol. 33, (32) 4185-4192.
10.1038/onc.2013.388
Wilson NJ, O'Toole EA, Milstone LM, Hansen CD, Shepherd AA, Al-Asadi E, Schwartz ME, McLean WHI et al.(2014). The molecular genetic analysis of the expanding pachyonychia congenita case collection. BRITISH JOURNAL OF DERMATOLOGY vol. 171, (2) 343-355.
10.1111/bjd.12958
Brooke MA, Etheridge SL, Kaplan N, Simpson C, O'Toole EA, Ishida-Yamamoto A, Marches O, Getsios S et al.(2014). iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function. Hum Mol Genet vol. 23, (15) 4064-4076.
10.1093/hmg/ddu120
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23225
Sommerlad M, Scott C, Harwood C, Kelsell D, O'Toole E (2014). Ichthyosis with striate keratoderma caused by a compound heterozygous mutation in ichthyin/NIPAL4. BRITISH JOURNAL OF DERMATOLOGY. vol. 171, 118-119.
Muttardi K, Nitoiu D, Kelsell DP, O'Toole EA, Batta K (2014). Peeling the surface of cystatin A defects. BRITISH JOURNAL OF DERMATOLOGY. vol. 171, 117-118.
Ooi J, Chinthapalli S, O'Toole E, Alazawi W(2014). PWE-142 Is Liver Disease Overlooked In Patients With Psoriasis?. Gut vol. 63 Suppl 1,
10.1136/gutjnl-2014-307263.402
O'Toole EA(2014). Type VII collagen and squamous cell carcinoma. Br J Dermatol vol. 170, (6)
10.1111/bjd.12868
Brown L, Waseem A, Cruz IN, Szary J, Gunic E, Mannan T, Unadkat M, Yang M et al.(2014). Desmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activation. Oncogene vol. 33, (18) 2363-2374.
10.1038/onc.2013.186
Caley M, Martins V, Moore K, Marshall J, O'Toole E (2014). Diverse roles for laminin-332 subunits in squamous cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 170, E26-E26.
Marsh S, Martins V, Caley M, Barnes M, Donaldson M, O'Toole E (2014). Global transcriptomic changes in primary keratinocytes with loss of basement membrane genes. BRITISH JOURNAL OF DERMATOLOGY. vol. 170, E37-E38.
Kopecki Z, Yang G, Jackson J, Melville E, Martin V, Matthew C, Proby C, Pouniotis D et al.(2014). TREATMENT OF SCC WITH FLIGHTLESS NEUTRALIZING ANTIBODY BLOCKS CELL INVASION AND REDUCES TUMOR GROWTH IN MICE. WOUND REPAIR AND REGENERATION vol. 22, (2) A49-A49.
Kulkarni M, O'Loughlin A, Vazquez R, Mashayekhi K, Rooney P, Greiser U, O'Toole E, O'Brien T et al.(2014). Use of a fibrin-based system for enhancing angiogenesis and modulating inflammation in the treatment of hyperglycemic wounds. Biomaterials vol. 35, (6) 2001-2010.
10.1016/j.biomaterials.2013.11.003
Jones M, Dry IR, Frampton D, Singh M, Kanda RK, Yee MB, Kellam P, Hollinshead M et al.(2014). RNA-seq analysis of host and viral gene expression highlights interaction between varicella zoster virus and keratinocyte differentiation. PLoS Pathog vol. 10, (1)
10.1371/journal.ppat.1003896
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55098
Blaydon DC, Lind LK, Plagnol V, Linton KJ, Smith FJD, Wilson NJ, McLean WHI, Munro CS et al.(2013). Mutations in AQP5, encoding a water-channel protein, cause autosomal-dominant diffuse nonepidermolytic palmoplantar keratoderma. Am J Hum Genet vol. 93, (2) 330-335.
10.1016/j.ajhg.2013.06.008
Blaydon DC, Lind L, Plagnol V, Linton KJ, South AP, Leigh IM, O'Toole EA, Lundstrom A et al. (2013). Aquaporin 5 (AQP5), a water channel protein, is mutated in autosomal dominant diffuse non-epidermolytic palmoplantar keratoderma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S139-S139.
Caley MP, Martins V, Moore K, Marshall JF, O'Toole EA (2013). Diverse roles for laminin 332 subunits in squamous cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S64-S64.
Martins VL, Caley MP, Moore K, Szentpetery Z, Murrell DF, Kim MH, McGrath JA, Cerio R et al. (2013). Loss of type VII collagen in cutaneous SCC increases angiogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S158-S158.
Ruban EL, Martins VL, Caley M, Raimondi C, Falasca M, O'Toole EA (2013). Phospholipase C-beta 4 regulates proliferation and invasion in cutaneous SCC. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S73-S73.
Marsh ST, Martins VL, Donaldson M, Braun K, O'Toole EA (2013). Regulation of normal epidermal homeostasis by the basement membrane. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S157-S157.
Szentpetery Z, Lovat PE, Bergamaschi D, O'Toole EA (2013). The receptor tyrosine kinase, Axl, as a therapeutic target in malignant melanoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S240-S240.
Marsh ST, Caley MP, Kwan A, O'Toole EA, Donaldson M (2013). Transcriptome profiling identifies novel functions of acitretin in human epidermis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S186-S186.
Martins VL, Caley M, O'Toole EA(2013). Matrix metalloproteinases and epidermal wound repair. Cell Tissue Res vol. 351, (2) 255-268.
10.1007/s00441-012-1410-z
Scott CA, Plagnol V, Nitoiu D, Bland PJ, Blaydon DC, Chronnell CM, Poon DS, Bourn D et al.(2013). Targeted sequence capture and high-throughput sequencing in the molecular diagnosis of ichthyosis and other skin diseases. J Invest Dermatol vol. 133, (2) 573-576.
10.1038/jid.2012.332
Brown LE, Gunic E, Unadkat M, Mannan T, Tsang S, Ahmed W, Valderrama F, O'Toole EA et al. (2012). Desmoglein 3 regulates cancer cell migration through Protein Kinase C dependent-ezrin activation. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S37-S37.
Kulkarni M, O'Loughlin A, Vazquez-Martinez R, Mashayekhi K, Greiser U, O'Toole E, O'Brien T, Malagon M et al.(2012). Fibrin mediated proangiogenic and secretory control gene therapy for compromised wound healing. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE vol. 6, 291-291.
Singh M, Caley M, Jones M, Breuer J, O'Toole E (2012). Keratin 15 and VZV replication in skin. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S112-S112.
Martins V, Caley M, Moore K, Murrell DF, McGrath JA, Chen M, Marshall JF, O'Toole EA (2012). Loss of keratinocyte type VII collagen in SCC increases TGF-beta signalling and angiogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S45-S45.
Szentpetery Z, Cichon M, Caley M, O'Toole E (2012). The receptor tyrosine kinase Axl regulates intercellular adhesion, epithelial-mesenchymal transition and stemness in cutaneous squamous cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S45-S45.
Wan H, Brown L, Gunic E, Mannan T, Tsang S, Valderrama F, O'Toole E (2012). Desmoglein 3 Regulates Cancer Cell Migration Through PKC Dependent-ezrin Activation. EUROPEAN JOURNAL OF CANCER. vol. 48, S45-S46.
10.1016/S0959-8049(12)70885-7
Tsang SM, Brown L, Lin K, Liu L, Piper K, O'Toole EA, Grose R, Hart IR et al.(2012). Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris. J Pathol vol. 227, (1) 81-93.
10.1002/path.3982
Marsh ST, Martins V, Braun K, Donaldson M, O'Toole EA (2012). The role of the basement membrane in stem cell maintenance and epidermal homeostasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S34-S34.
Martins V, Caley M, Moore K, Chen M, Marshall J, O'Toole E (2012). Loss of type VII collagen in squamous cell carcinoma increases angiogenesis in vitro and in vivo. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e25-e26.
Tull T, Chu A, O'Toole E, Teixeira F, Schmid K, Punjabi S (2012). Macrocephaly: Capillary malformation with the neuroradiologic features of Sturge-Weber syndrome: A syndrome overlap?. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. vol. 66, AB95-AB95.
Scott C, Bland P, Plagnol V, Nitoiu D, Poon D, O'Toole E, Kelsell D (2012). Next-generation sequencing in genetic diagnosis of skin disease. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e34-e34.
Ruban EL, Martins VL, Falasca M, O'Toole EA (2012). Phospholipase C signalling in cutaneous squamous cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e23-e24.
Marsh S, Martins V, Braun K, Donaldson M, O'Toole E (2012). The role of the basement membrane in normal epidermal homeostasis. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e32-e32.
Blaydon DC, Biancheri P, Di W-L, Plagnol V, Cabral RM, Brooke MA, van Heel DA, Ruschendorf F et al.(2011). Inflammatory skin and bowel disease linked to ADAM17 deletion. N Engl J Med vol. 365, (16) 1502-1508.
10.1056/NEJMoa1100721
Ruban E, Martins V, Falasca M, O'Toole E (2011). Phospholipase C signalling in cutaneous squamous cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 131, S32-S32.
Marsh S, Martins V, O'Toole E (2011). The role of the basement membrane in normal epidermal homeostasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 131, S33-S33.
Dewan P, Robinson J, O'Toole E, Paige DG, Goldsmith P (2011). Need for transition in dermatology: a study from a London teaching hospital. BRITISH JOURNAL OF DERMATOLOGY. vol. 165, 20-20.
Dewan P, Terron-Kwiatkowski A, Rajpopat S, Dopping-Hepenstal PJ, McGrath JA, Baty D, O'Toole EA (2011). Recessive epidermolytic palmoplantar keratoderma caused by a keratin 1 mutation. BRITISH JOURNAL OF DERMATOLOGY. vol. 165, 120-120.
Rajpopat S, Moss C, Mellerio J, Vahlquist A, Gånemo A, Hellstrom-Pigg M, Ilchyshyn A, Burrows N et al.(2011). Harlequin ichthyosis: a review of clinical and molecular findings in 45 cases. Arch Dermatol vol. 147, (6) 681-686.
10.1001/archdermatol.2011.9
Cichon MA, Mackenzie IC, O'Toole EA (2011). Axl plays a role in cell adhesion and 'stemness' in cutaneous SCC. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 908-909.
Martins VL, Moore K, Chen M, Marshall J, O'Toole EA (2011). Loss of type VII collagen in SCC leads to increased invasion and TGF-beta signalling in vivo. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 910-910.
Ruban EL, Martins VL, Falasca M, O'Toole EA (2011). Phospholipase C signalling in cutaneous squamous cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 935-935.
Dewan P, Terron-Kwiatkowski A, Rajpopat S, Baty D, O'Toole EA (2011). Recessive epidermolytic palmoplantar keratoderma caused by a keratin 1 mutation. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 932-932.
Wong S, Rizvi H, Cerio R, O'Toole EA(2011). An unusual case of vulval papulonecrotic tuberculid. Clin Exp Dermatol vol. 36, (3) 277-280.
10.1111/j.1365-2230.2010.03925.x
Martins V, Moore K, Chen M, Marshall J, O'Toole EA (2011). Loss of type VII collagen in squamous cell carcinoma leads to increased invasion and TGF-beta signalling in vivo. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 131, S33-S33.
Talsania N, Jolliffe V, O'Toole EA, Cerio R(2011). Platelike osteoma cutis. J Am Acad Dermatol vol. 64, (3) 613-615.
10.1016/j.jaad.2009.07.049
Martinez-Levasseur LM, Gendron D, Knell RJ, O'Toole EA, Singh M, Acevedo-Whitehouse K(2011). Acute sun damage and photoprotective responses in whales. Proceedings of the Royal Society B vol. 278, (1711) 1581-1586.
10.1098/rspb.2010.1903
Scott CA, Tattersall D, O'Toole EA, Kelsell DP(2011). Connexins in epidermal homeostasis and skin disease. Biochimica et Biophysica Acta - Biomembranes
10.1016/j.bbamem.2011.09.004
Scott CA, O'Toole EA, Mohungoo MJ, Messenger A, Kelsell DP(2011). Novel and recurrent connexin 30.3 and connexin 31 mutations associated with erythrokeratoderma variabilis. Clin Exp Dermatol vol. 36, (1) 88-90.
10.1111/j.1365-2230.2010.03945.x
Martins V, Chen M, Purdie K, O'Toole E (2010). Loss of type VII collagen in cutaneous SCC increases cell invasion through TGF-beta signalling. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 130, S19-S19.
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