Publications: Prof Kanwal Pasi
Bowles L, Platton S, Yartey N, Dave M, Lee K, Hart DP, MacDonald V, Green L et al.(2020).
Lupus Anticoagulant and Abnormal Coagulation Tests in Patients with Covid-19. N Engl J Med
Nolan B, Mahlangu J, Pabinger I, Young G, Konkle BA, Barnes C, Nogami K, Santagostino E et al.(2020).
Recombinant factor VIII Fc fusion protein for the treatment of severe haemophilia A: Final results from the ASPIRE extension study. Haemophilia
vol. 26,
(3)
494-502.
Pierce GF, Pasi KJ, Coffin D, Kaczmarek R, Lillicrap D, Mahlangu J, Rottellini D, Sannié T et al.(2020).
Towards a global multidisciplinary consensus framework on haemophilia gene therapy: Report of the 2nd World Federation of Haemophilia Gene Therapy Round Table. Haemophilia
vol. 26,
(3)
443-449.
Blacker E, MacDonald V, Hart DP, Bowles L, Cavenagh JD, Forsyth K, Morris A, Foley C et al. (2020).
A case of acquired von Willebrand syndrome becoming IVIg responsive following bortezomib treatment despite minimal paraprotein response. BRITISH JOURNAL OF HAEMATOLOGY.
vol. 189,
272-272.
Sivapalaratnam S, Muczynski V, Collins J, Pasi J, Downes K, Nathwani A, Gomez K (2020).
Gain of function variant of prothrombin (p.R541W) causes dominant heritable thrombosis and is associated with antithrombin resistance. BRITISH JOURNAL OF HAEMATOLOGY.
vol. 189,
42-43.
Pasi KJ, Rangarajan S, Mitchell N, Lester W, Symington E, Madan B, Laffan M, Russell CB et al.(2020).
Multiyear follow-up of aav5-hfviii-sq gene therapy for hemophilia a. New England Journal of Medicine
vol. 382,
(1)
29-40.
Pasi KJ, Fischer K, Ragni M, Kulkarni R, Ozelo MC, Mahlangu J, Shapiro A, P¿Ng S et al.(2020).
Long-term safety and sustained efficacy for up to 5 years of treatment with recombinant factor IX Fc fusion protein in subjects with haemophilia B: Results from the B-YOND extension study. Haemophilia
Akay M, Zaidi A, Vaidya S, Sivapalaratnam S, Theodoulou A, Platton S, Hart D, Pasi J et al.(2019).
A novel variant causing α2 antiplasmin deficiency: case report and experience in a UK centre. Br J Haematol
vol. 187,
(2)
e42-e44.
Pipe S, Leebeek FWG, Ferreira V, Sawyer EK, Pasi J(2019).
Clinical Considerations for Capsid Choice in the Development of Liver-Targeted AAV-Based Gene Transfer. Molecular Therapy - Methods and Clinical Development
vol. 15,
170-178.
Stanford S, Pink R, Creagh D, Clark A, Lowe G, Curry N, Pasi J, Perry D et al.(2019).
Adenovirus-associated antibodies in UK cohort of hemophilia patients: A seroprevalence study of the presence of adenovirus-associated virus vector-serotypes AAV5 and AAV8 neutralizing activity and antibodies in patients with hemophilia A. Res Pract Thromb Haemost
vol. 3,
(2)
261-267.
Prasannan N, Chatterjee B, Pasi J, McDonald V, Maposa W, Ricketts W, Lau K, Giaslakiotis K et al. (2019).
A Case of Acquired Haemophilia secondary to Atypical Carcinoid Tumour. BRITISH JOURNAL OF HAEMATOLOGY.
vol. 185,
196-196.
Booth CS, Bowles L, Hart D, Pasi J, Forsyth K, Morris A, Kaya B, McDonald V (2019).
Double Double Trouble - Two Cases of Acquired Immune Thrombocytopenia Complicating Congenital Haemophilia. BRITISH JOURNAL OF HAEMATOLOGY.
vol. 185,
137-137.
Pasi J, Georgiev P, Creagh MD, Lissitchkov T, Bevan D, Austin S, Hay CR, Hegemann I et al. (2019).
The role of antithrombin lowering in patients with hemophilia: Hemostatic control pre- and post-fitusiran dosing interruption. HAEMOPHILIA.
vol. 25,
33-34.
Lissitchkov T, Klukowska A, Pasi J, Kessler CM, Klamroth R, Liesner RJ, Belyanskaya L, Walter O et al.(2019).
Efficacy and safety of simoctocog alfa (Nuwiq®) in patients with severe hemophilia A: a review of clinical trial data from the GENA program. Ther Adv Hematol
vol. 10,
Shapiro AD, Pasi KJ, Ozelo MC, Kulkarni R, Barnowski C, Winding B, Szamosi J, Lethagen S(2019).
Extending recombinant factor IX Fc fusion protein dosing interval to 14 or more days in patients with hemophilia B. Res Pract Thromb Haemost
vol. 3,
(1)
109-113.
Ito Y, Carss KJ, Duarte ST, Hartley T, Keren B, Kurian MA, Marey I, Charles P et al.(2018).
De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. American Journal of Human Genetics
vol. 103,
(1)
144-153.
Rangarajan S, Walsh L, Lester W, Perry D, Madan B, Laffan M, Yu H, Vettermann C et al.(2017).
AAV5-factor VIII gene transfer in severe hemophilia a. New England Journal of Medicine
vol. 377,
(26)
2519-2530.
Lissitchkov T, Rusen L, Georgiev P, Windyga J, Klamroth R, Gercheva L, Nemes L, Tiede A et al.(2017).
PK-guided personalized prophylaxis with Nuwiq® (human-cl rhFVIII) in adults with severe haemophilia A. Haemophilia
vol. 23,
(5)
697-704.
Pasi KJ, Rangarajan S, Georgiev P, Mant T, Creagh MD, Lissitchkov T, Bevan D, Austin S et al.(2017).
Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy. N Engl J Med
Shapiro AD, Mahlangu JN, Perry D, Pasi J, Quon DV, Chowdary P, Tsao E, Li S et al.(2017).
Treatment of bleeding episodes with recombinant factor VIII Fc fusion protein in A-LONG study subjects with severe haemophilia A. Haemophilia
vol. 23,
(3)
392-399.
Konkle B, Pasi K, Young G, Recht M, Quon D, Tsao E, Winding B, Lethagen S et al. (2017).
Long-term Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) Prophylaxis in Adults, Adolescents, and Children with Severe Hemophilia A: Longitudinal Analysis of A-LONG and ASPIRE Studies. HAEMOPHILIA.
vol. 23,
21-22.
Iorio A, Barbara AM, Makris M, Fischer K, Castaman G, Catarino C, Gilman E, Kavakli K et al.(2017).
Natural history and clinical characteristics of inhibitors in previously treated haemophilia A patients: a case series. Haemophilia
vol. 23,
(2)
255-263.
Pasi KJ, Perry D, Mahlangu JN, Konkle B, Rangarajan S, Hanabusa H, Pabinger I, Brown SA et al. (2017).
Dosing Regimens Before and During Long-Term Treatment With Recombinant Factor VIII Fc Fusion Protein (rFVIIIFC) in Adults And Adolescents With Severe Haemophilia A: an Updated Analysis Of The Aspire Study. HAEMOPHILIA.
vol. 23,
89-90.
Nolan B, Young G, Mahlangu JN, Liesner R, Pasi KJ, Yuan H, Winding B, Ramirez-Santiago A et al. (2017).
Dosing Regimens Before and During Long-Term Treatment with Recombinant Factor VIII FC Fusion Protein (rFVIIIFc) in Children with Severe Haemophilia A: An Updated Analysis of the ASPIRE Study. HAEMOPHILIA.
vol. 23,
42-43.
Pasi J (2017).
How to Make a Choice Among the Different Extended Half-life Products?. HAEMOPHILIA.
vol. 23,
23-23.
Mahlangu JN, Shapiro AD, Pasi KJ, Ragni MV, Ozelo MC, Oldenburg J, Matsushita T, Baker RI et al. (2017).
Individualised Prophylaxis with Recombinant Factor IX FC Fusion Protein (RFIXFC) in Adults/Adolescents With Haemophilia B: Updated Interim Results of the B-YOND Extension Study. HAEMOPHILIA.
vol. 23,
85-86.
Rangarajan S, Georgiev P, Mant T, Creagh MD, Lissitchkov T, Bevan D, Austin S, Hay CR et al. (2017).
Management of Bleed Events in the Phase 1 Study of Fitusiran, an Investigational RNAi Therapeutic Targeting Antithrombin for the Treatment of Hemophilia in Patients with and Without Inhibitors. HAEMOPHILIA.
vol. 23,
20-21.
Pasi KJ, Georgiev P, Mant T, Creagh MD, Lissitchkov T, Bevan D, Austin S, Hay CR et al. (2017).
Phase 1 and Phase 1/2 Extension Study of Fitusiran, an Investigational Rnai Therapeutic Targeting Antithrombin for the Treatment of Hemophilia: Updated Results in Patients With Inhibitors. HAEMOPHILIA.
vol. 23,
88-89.
Chowdary P, Georgiev P, Mant T, Creagh MD, Lissitchkov T, Bevan D, Austin S, Hay CR et al. (2017).
Phase 1 and Phase 1/2 Extension Study of Fitusiran, an Investigational Rnai Therapeutic Targeting Antithrombin for the Treatment of Hemophilia: Updated Results in Patients Without Inhibitors. HAEMOPHILIA.
vol. 23,
118-119.
Pasi KJ, Fischer K, Ragni M, Nolan B, Perry DJ, Kulkarni R, Ozelo M, Mahlangu J et al.(2017).
Long-term safety and efficacy of extended-interval prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) in subjects with haemophilia B. Thrombosis and Haemostasis
vol. 117,
(3)
508-518.
Miners AH, Krishnan S, Pasi KJ(2016).
Predicting the outcomes of using longer-acting prophylactic factor VIII to treat people with severe hemophilia A: a hypothetical decision analysis. J Thromb Haemost
vol. 14,
(11)
2141-2147.
Shapiro AD, Kulkarni R, Ozelo M, Windyga J, Pasi KJ, Perry DJ, Desai C, Mei B (2016).
ANALYSIS OF ANNUALIZED BLEEDING RATES AND BASELINE CHARACTERISTICS IN SUBJECTS WITH A 14-DAY OR LONGER DOSING INTERVAL IN THE PHASE 3 B-LONG STUDY OF RECOMBINANT FACTOR IX FC FUSION PROTEIN. AMERICAN JOURNAL OF HEMATOLOGY.
vol. 91,
E406-E406.
Pasi KJ, Georgiev P, Mant T, Creagh MD, Lissitchkov T, Bevan D, Austin S, Hay CR et al.(2016).
A Subcutaneously Administered Investigational RNAi Therapeutic, Fitusiran (ALN-AT3), Targeting Antithrombin for Treatment of Hemophilia: Interim Results in Patients with Hemophilia A or B. HAEMOPHILIA
vol. 22,
76-76.
Konkle BA, Pasi KJ, Perry DJ, Mahlangu J, Rangarajan S, Hanabusa H, Pabinger I, Lethagen S et al.(2016).
Dosing regimens before and following long-term treatment with recombinant factor VIII Fc fusion protein (rFVIIIFc) in adults and adolescents with severe hemophilia A. HAEMOPHILIA
vol. 22,
44-44.
Nolan B, Liesner R, Young G, Mahlangu J, Pasi KJ, Lethagen S, Cristiano LM, Yuan H et al.(2016).
Dosing regimens before and following long-term treatment with recombinant factor VIII Fc fusion protein (rFVIIIFc) in children with severe hemophilia A. HAEMOPHILIA
vol. 22,
48-49.
Klamroth R, Bichler J, Jansen M, Belyanskaya L, Knaub S, Kessler C, Pasi J(2016).
Experience with Nuwiq (R) in clinical trials with previously treated paediatric and adult patients. HAEMOPHILIA
vol. 22,
47-47.
Maposa W, Bowles L, Fenton R, Foley C, Hart DP, Morris A, Pasi J, Patel V et al.(2016).
Link nurse teaching day to bring haemophilia to ward nurses. HAEMOPHILIA
vol. 22,
29-29.
Mahlangu J, Ragni MV, Shapiro AD, Pasi KJ, Ozelo MC, Oldenburg J, Matsushita T, Baker RI et al.(2016).
Long-term safety and efficacy of recombinant factor IX Fc fusion protein (rFIXFc) in adults/adolescents with hemophilia B: Longitudinal analysis of B-LONG and B-YOND. HAEMOPHILIA
vol. 22,
47-47.
Kulkarni R, Pasi KJ, Liesner R, Hanabusa H, Feng J, Ferrante F, Mei B, Jain N(2016).
Post hoc analysis to evaluate the effect of recombinant factor IX Fc fusion protein (rFIXFc) prophylaxis in adults and adolescents with target joints and hemophilia B. HAEMOPHILIA
vol. 22,
44-44.
Berntorp E, Hart D, Mancuso ME, d'Oiron R, Perry D, O'Mahony B, Kaczmarek R, Crato M et al.(2016).
The first Team Haemophilia Education meeting, 2015, Amsterdam, The Netherlands. Eur J Haematol
vol. 97 Suppl 83,
3-18.
Austin S, Chowdary P, Kadam A, Laffan M, Dolan G, Pasi J(2016).
Use of long term prophylaxis in London haemophilia centres. HAEMOPHILIA
vol. 22,
110-110.
Collins P, Chalmers E, Chowdary P, Keeling D, Mathias M, O'Donnell J, Pasi KJ, Rangarajan S et al.(2016).
The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO. Haemophilia
Mahlangu J, Shapiro AD, Pasi KJ, Ragni MV, Ozelo MC, Oldenburg J, Matsushita T, Baker RI et al.(2016).
Extended-Interval Prophylaxis with Recombinant Factor IX FC Fusion Protein (rFIXFc) in Adults/Adolescents with Haemophilia B: Interim Results of the B-YOND Extension Study. HAEMOPHILIA
vol. 22,
46-47.
Pasi KJ, Pabinger I, Kerlin BA, Kulkarni R, Nolan B, Wang M, Liesner R, Brown SA et al.(2016).
Long-Term Efficacy of Recombinant Factor VIII FC Fusion Protein (rFVIIIFC) Prophylaxis in Paediatric, Adolescent, and Adult Subjects with Target Joints and Severe Haemophilia A. HAEMOPHILIA
vol. 22,
21-21.
Pasi KJ, Perry DJ, Mahlangu J, Konkle BA, Rangarajan S, Brown SA, Hanabusa H, Jackson S et al.(2016).
Long-Term Safety and Efficacy of Recombinant Factor VIII FC Fusion Protein (rFVIIIFc) in Adults and Adolescents with Severe Haemophilia A: An Updated Interim Analysis of the Aspire Study. HAEMOPHILIA
vol. 22,
64-65.
Windyga J, Kulkarni R, Shapiro AD, Ragni MV, Pasi KJ, Ozelo MC, Tsao E, Allen G et al.(2016).
Low Bleeding Rates with Increase or Maintenance of Physical Activity in Patients Treated with Recombinant Factor IX FC Fusion Protein (rFIXFc) in the B-LONG and Kids B-LONG Studies. HAEMOPHILIA
vol. 22,
19-20.
Nolan B, Young G, Mahlangu J, Liesner R, Pasi KJ, Lethagen S, Cristiano LM, Li X et al.(2016).
Second Interim Analysis of the Aspire Study Evaluating Long-Term Safety and Efficacy of Recombinant Factor VIII FC Fusion Protein (rFVIIIFc) in Children with Severe Haemophilia A. HAEMOPHILIA
vol. 22,
65-66.
Stephensen D, Patel V, Elliot K, Bowles L, Hart DP, Pasi J(2016).
The Relationship Between Clinical Joint Health and Functional Ability in Adult Men with Haemophilia. HAEMOPHILIA
vol. 22,
51-51.
Powell JS, Apte S, Chambost H, Hermans C, Jackson S, Josephson NC, Mahlangu JN, Ozelo MC et al.(2016).
Long-acting recombinant factor IX Fc fusion protein (rFIXFc) for perioperative management of subjects with haemophilia B in the phase 3 B-LONG study. British Journal of Haematology
vol. 168,
(1)
124-134.
Nolan B, Mahlangu J, Perry D, Young G, Liesner R, Konkle B, Rangarajan S, Brown S et al.(2016).
Long-term safety and efficacy of recombinant factor VIII Fc fusion protein (rFVIIIFc) in subjects with haemophilia A. Haemophilia
vol. 22,
(1)
72-80.
Pasi KJ, Georgiev P, Mant T, Creagh MD, Lissitchkov T, Bevan D, Austin S, Hay CR et al. (2015).
A Subcutaneously Administered Investigational RNAi Therapeutic (ALN-AT3) Targeting Antithrombin for Treatment of Hemophilia: Interim Weekly and Monthly Dosing Results in Patients with Hemophilia A or B. BLOOD.
vol. 126,
Mahlangu J, Shapiro AD, Pasi KJ, Ragni MV, Ozelo MC, Oldenburg J, Matsushita T, Baker RI et al. (2015).
Extended-Interval Prophylaxis with rFIXFc in Adults and Adolescents with Hemophilia B: Interim Results of the B- YOND Extension Study. BLOOD.
vol. 126,
Kerlin BA, Kulkarni R, Nolan B, Wang M, Pasi KJ, Liesner R, Brown S, Hanabusa H et al. (2015).
Long-Term Efficacy of rFVIIIFc Prophylaxis in Pediatric, Adolescent, and Adult Subjects with Target Joints and Severe Hemophilia A. BLOOD.
vol. 126,
Pasi KJ, Perry DJ, Mahlangu J, Konkle BA, Rangarajan S, Brown S, Hanabusa H, Jackson S et al. (2015).
Long-Term Safety and Efficacy of rFVIIIFc in Adults and Adolescents with Severe Hemophilia A: A Longitudinal Analysis of A- LONG and ASPIRE. BLOOD.
vol. 126,
Kulkarni R, Shapiro AD, Windyga J, Ragni MV, Pasi KJ, Ozelo MC, Tsao E, Mei B (2015).
Low Bleeding Rates with Increase or Maintenance of Physical Activity in Patients Treated with Recombinant Factor IX Fc Fusion Protein ( rFIXFc) in the B-LONG and Kids B-LONG Studies. BLOOD.
vol. 126,
Klamroth R, Lissitchkov T, Rusen L, Walter O, Bichler J, Pasi KJ, Tiede A, Knaub S (2015).
Personalized Prophylaxis with Human-CI Recombinant FVIII in HA Patients. BLOOD.
vol. 126,
Patel V, Hart D, Bowles L, Pasi J, Jawad A(2015).
Intra-Articular Hyaluronate Injections in Severe Haemophilia Patients With Moderate to Severe Arthritis of the Ankle. HAEMOPHILIA
vol. 21,
(6)
E549-E549.
Batty P, Moore GW, Platton S, Maloney JC, Palmer B, Bowles L, Pasi KJ, Rangarajan S et al.(2015).
Diagnostic accuracy study of a factor VIII ELISA for detection of factor VIII antibodies in congenital and acquired haemophilia A. Thromb Haemost
vol. 114,
(4)
804-811.
Batty P, Honke A, Bowles L, Hart DP, Pasi KJ, Uprichard J, Austin SK(2015).
Ongoing risk of thrombosis with factor XI concentrate: 5years experience in two centres. HAEMOPHILIA
vol. 21,
(4)
490-495.
Sorensen B, Mant T, Georgiev P, Rangarajan S, Pasi JK, Creagh D, Bevan DH, Austin S et al.(2015).
A subcutaneously administered investigational RNAi therapeutic (ALN-AT3) targeting antithrombin for treatment of hemophilia: interim phase 1 study results in patients with hemophilia A or B. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 13,
176-177.
Gwynn S, Arya R, McPhelim J, Talbot T, Pasi J, Fortes-Mayer G, Kedia N, Kokiet S et al.(2015).
Cancer associated thrombosis: developing consensus guidance to improve patient care and outcomes. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 13,
543-544.
Klamroth R, Lissitchkov T, Rusen L, Walter O, Knaub S, Bichler J, Pasi J, Tiede A(2015).
Personalizedprophylaxis with Human-CL RHFVIII in hemophilia A patients. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 13,
850-851.
Young G, Mahlangu J, Kulkarni R, Nolan B, Liesner R, Pasi J, Barnes C, Neelakantan S et al.(2015).
Recombinant factor VIII Fc fusion protein for the prevention and treatment of bleeding in children with severe hemophilia A. J Thromb Haemost
vol. 13,
(6)
967-977.
Nolan B, Young G, Mahlangu J, Liesner R, Pasi J, Cristiano LM, Li X, Pierce GF et al.(2015).
Interim Analysis Of The ASPIRE Study Evaluating Long-term Safety And Efficacy Of Recombinant Factor VIII FC (RFVIIIFC) In Children With Severe Haemophilia A. HAEMOPHILIA
vol. 21,
58-59.
Pasi J, Perry D, Mahlangu J, Konkle B, Rangarajan S, Brown SA, Hanabusa H, Jackson S et al.(2015).
Long-Term Safety and Efficacy of Recombinant Factor VIII FC (RFVIIIFC) in Adults and Adolescents With Severe Haemophilia A: An Interim Analysis of The ASPIRE Study. HAEMOPHILIA
vol. 21,
52-53.
Young G, Mahlangu J, Kulkarni R, Nolan B, Liesner R, Pasi J, Barnes C, Neelakantan S et al.(2015).
Safety, Efficacy, and Pharmacokinetics of Recombinant Factor VIII FC Fusion Protein (RFVIIIFC) in Previously Treated Paediatric Subjects with Severe Haemophilia A (Kids A-LONG). HAEMOPHILIA
vol. 21,
32-32.
Windyga J, Ragni M, Pasi J, Shapiro AD, Ozelo M, Innes A, Mei B(2015).
Subject-Reported Changes in Physical Activity During The B-LONG Study of Recombinant Factor IX FC Fusion Protein (RFIXFC) For Severe Haemophilia B. HAEMOPHILIA
vol. 21,
29-29.
Powell J, Shapiro A, Ragni M, Negrier C, Windyga J, Ozelo M, Pasi J, Baker R et al.(2015).
Switching to recombinant factor IX Fc fusion protein prophylaxis results in fewer infusions, decreased factor IX consumption and lower bleeding rates. British Journal of Haematology
vol. 168,
(1)
113-123.
Khair K, Batty P, Riat R, Bowles L, Burgess C, Chen YH, Hart D, Platton S et al.(2015).
Wilate use in 47 children with von Willebrand disease: The North London paediatric haemophilia network experience. Haemophilia
vol. 21,
(1)
e44-e50.
Powell JS, Ozelo M, Ragni MV, Pasi J, Perry DJ, Zhu Y, Mei B, Pierce GF et al.(2014).
Predicting FIX Activity in Prophylaxis Patients Using Recombinant FIX Fc Fusion Protein for Treatment of Bleeding Episodes. BLOOD
vol. 124,
(21)
Quon DV, Mahlangu JN, Shapiro AD, Pasi J, Zhu Y, Pierce GF, Li L, Allen G (2014).
Predicting FVIII Activity in Patients Who Use Recombinant FVIII Fc Fusion Protein for Prophylaxis and Treatment of Bleeding Episodes. BLOOD.
vol. 124,
Young G, Mahlangu JN, Kulkarni R, Nolan B, Liesner R, Pasi J, Barnes C, Neelakantan S et al. (2014).
Safety, Efficacy, and Pharmacokinetics of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously-Treated Children with Severe Hemophilia a (Kids-ALONG). BLOOD.
vol. 124,
Shapiro AD, Ragni MV, Kulkarni R, Oldenberg J, Srivastava A, Quon DV, Pasi KJ, Hanabusa H et al.(2014).
Recombinant factor VIII Fc fusion protein: Extended-interval dosing maintains low bleeding rates and correlates with von Willebrand factor levels. Journal of Thrombosis and Haemostasis
vol. 12,
(11)
1788-1800.
Batty P, Platton S, Bowles L, Pasi KJ, Hart DP(2014).
Pre-analytical heat treatment and a FVIII ELISA improve Factor VIII antibody detection in acquired haemophilia A. Br J Haematol
vol. 166,
(6)
953-956.
Batty P, Chen YH, Bowles L, Hart DP, Platton S, Pasi KJ(2014).
Safety and efficacy of a von Willebrand factor/factor VIII concentrate (Wilate®): A single centre experience. Haemophilia
Young G, Mahlangu J, Kulkarni R, Nolan B, Liesner R, Pasi J, Barnes C, Neelakantan S et al. (2014).
KIDS A-LONG: SAFETY, EFFICACY, AND PHARMACOKINETICS OF LONG-ACTING RECOMBINANT FACTOR VIII FC FUSION PROTEIN (RFVIIIFC) IN PREVIOUSLY-TREATED PAEDIATRIC SUBJECTS WITH HAEMOPHILIA A. HAEMATOLOGICA.
vol. 99,
791-791.
Kulkarni R, Ragni MV, Baker RI, Pasi J, Manco-Johnson MJ, Potts J, Brennan A, Pierce GF(2014).
Analysis of clinical target joint bleeding on prophylactic regimens with recombinant Factor VIII Fc fusion protein in patients with severe hemophilia A. HAEMOPHILIA
vol. 20,
94-94.
Fong F, Davies J, Fearne J, Pasi J(2014).
Dental care pathway for children with hematological disorders. HAEMOPHILIA
vol. 20,
132-132.
Pasi J, Ragni M, Ozelo M, Valentino LA, Jiang H, Dodd N, Robinson B, Mei B et al.(2014).
Recombinant factor IX Fc fusion protein as episodic treatment for bleeding: Analysis from the B-LONG Study. HAEMOPHILIA
vol. 20,
15-16.
Negrier C, Powell J, Shapiro A, Ragni M, Windyga J, Ozelo M, Pasi J, Baker R et al.(2014).
Recombinant factor IX Fc fusion protein dosing conversion: extended-interval dosing yields low bleeding rates and a reduction in factor consumption. HAEMOPHILIA
vol. 20,
187-187.
Oldenberg J, Shapiro AD, Ragni MV, Kulkarni R, Srivastava A, Quon DV, Pasi KJ, Hanabusa H et al.(2014).
Switching to treatment with recombinant factor VIII Fc fusion protein: extended dosing interval yields low bleeding rates with comparable factor consumption and is correlated with von Willebrand Factor levels. HAEMOPHILIA
vol. 20,
187-187.
Pasi J, Potts J, Li S, Brennan A, Pierce GF, Jiang H(2014).
Recombinant factor VIIIFc fusion protein in severe haemophilia A: association between bleeding and FVIII activity in A-LONG. HAEMOPHILIA
vol. 20,
78-79.
Mahlangu J, Powell JS, Ragni MV, Chowdary P, Josephson NC, Pabinger I, Hanabusa H, Gupta N et al.(2014).
Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A. BLOOD
vol. 123,
(3)
317-325.
Powell JS, Pasi KJ, Ragni MV, Ozelo MC, Valentino LA, Mahlangu JN, Josephson NC, Perry D et al.(2013).
Phase 3 Study of Recombinant Factor IX Fc Fusion Protein in Hemophilia B. NEW ENGLAND JOURNAL OF MEDICINE
vol. 369,
(24)
2313-2323.
Mahlangu J, Powell J, Ragni M, Chowdary P, Josephson N, Pabinger I, Hanabusa H, Gupta N et al.(2013).
A-LONG: results from a Phase 3 study of safety, efficacy, and pharmacokinetics of long-lasting recombinant factor VIII Fc fusion protein (rFVIIIFc). JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 11,
168-169.
Li S, Diao L, Powell J, Shapiro AD, Josephson N, Pasi J, Perry D, Ragni M et al.(2013).
Clinical implications of population pharmacokinetics of rFIXFc in routine prophylaxis, control of bleeding and perioperative management for haemophilia B patients. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 11,
358-359.
Platton SJ, Batty P, Bowles L, Pasi J, Hart DP(2013).
Heat treatment and immunological testing substantially improves the detection of factor VIII antibodies in acquired haemophilia A. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 11,
670-670.
Batty P, Moore GW, Platton SJ, Maloney JC, Bowles L, Pasi J, Rangarajan S, Hart DP(2013).
Immunological detection of factor VIII antibodies in congenital and acquired haemophilia A. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 11,
930-930.
Mahlangu J, Powell J, Josephson N, Klamroth R, Parra Lopez R, Morfini M, Oldenburg J, Pasi J et al.(2013).
Long-lasting recombinant factor VIII Fc fusion (rFVIIIFc) for perioperative management of subjects with haemophilia A in the phase 3 A-LONG study. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 11,
459-459.
Batty P, Honke A, Uprichard J, Bowles L, Hart DP, Pasi J, Austin S(2013).
Ongoing risk of thrombosis with factor XI concentrate: 5 years experience in two centres. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
vol. 11,
708-708.
Neelakantan S, Li S, Powell J, Josephson N, Pasi J, Perry D, Shapiro AD, Ragni M et al.(2013).
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