Menu
 
Research menu
Jump to menu

Publications:  Prof Patricia Munroe

Ntalla I, Weng LC, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD et al.(2020). Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nature Communications vol. 11, (1)
10.1038/s41467-020-15706-x
Raisi-Estabragh Z, McCracken C, Bethell MS, Cooper J, Cooper C, Caulfield MJ, Munroe PB, Harvey NC et al.(2020). Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank. Journal of public health (Oxford, England)
10.1093/pubmed/fdaa095
https://qmro.qmul.ac.uk/xmlui/handle/123456789/65624
Raisi-Estabragh Z, Cooper J, Judge R, Khanji M, Munroe P, Cooper C, Harvey NC, Petersen S(2020). Age, sex and disease-specific associations between resting heart rate and cardiovascular mortality in the UK BIOBANK. PLoS One
10.1371/journal.pone.0233898
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64752
Raisi-Estabragh Z, Kenawy AAM, Aung N, Cooper J, Munroe PB, Harvey NC, Petersen SE, Khanji MY(2020). Variation in left ventricular cardiac magnetic resonance normal reference ranges: systematic review and meta-analysis. Eur Heart J Cardiovasc Imaging
10.1093/ehjci/jeaa089
de las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR et al.(2020). Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Molecular Psychiatry
10.1038/s41380-020-0719-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64748
Nicholls HL, John CR, Watson DS, Munroe PB, Barnes MR, Cabrera CP(2020). Reaching the End-Game for GWAS: Machine Learning Approaches for the Prioritization of Complex Disease Loci. Frontiers in Genetics vol. 11,
10.3389/fgene.2020.00350
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64760
Alimadadi A, Aryal S, Manandhar I, Munroe PB, Joe B, Cheng X(2020). Artificial intelligence and machine learning to fight COVID-19. Physiol Genomics vol. 52, (4) 200-202.
10.1152/physiolgenomics.00029.2020
Alimadadi A, Munroe PB, Joe B, Cheng X(2020). Meta-analysis of dilated cardiomyopathy using cardiac rna-seq transcriptomic datasets. Genes vol. 11, (1)
10.3390/genes11010060
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63743
Ramírez J, van Duijvenboden S, Young WJ, Orini M, Lambiase PD, Munroe PB, Tinker A(2020). Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval. American Journal of Human Genetics
10.1016/j.ajhg.2020.04.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/65500
Aung N, Doimo S, Ricci F, Sanghvi MM, Pedrosa C, Woodbridge SP, Al-Balah A, Zemrak F et al.(2020). Prognostic significance of left ventricular noncompaction: Systematic review and meta-analysis of observational studies. Circulation: Cardiovascular Imaging
10.1161/CIRCIMAGING.119.009712
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63688
Fung K, Ramírez J, Warren HR, Aung N, Lee AM, Tzanis E, Petersen SE, Munroe PB(2019). Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants. Scientific Reports vol. 9, (1)
10.1038/s41598-019-45703-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58757
Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ et al.(2019). Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. Nature Communications vol. 10, (1)
10.1038/s41467-019-12958-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63832
Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Jakupovi¿ H, Chasman DI et al.(2019). Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications vol. 10, (1)
10.1038/s41467-018-08008-w
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58847
Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK et al.(2019). Associations of autozygosity with a broad range of human phenotypes. Nature Communications vol. 10, (1) 4957-4957.
10.1038/s41467-019-12283-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61102
Munroe PB, Ramírez J, van Duijvenboden S(2019). Resting Heart Rate and Type 2 Diabetes: A Complex Relationship in Need of Greater Understanding. Journal of the American College of Cardiology vol. 74, (17) 2175-2177.
10.1016/j.jacc.2019.08.1030
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62362
Teumer A, Trenkwalder T, Kessler T, Jamshidi Y, van den Berg ME, Kaess B, Nelson CP, Bastiaenen R et al.(2019). KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern. JCI insight
10.1172/jci.insight.131156
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62342
Timasheva Y, Zudina L, Balkhiyarova Z, Kaakinen M, Munroe P, Prokopenko I (2019). Analysis of cardiometabolic traits highlights shared biological pathways. EUROPEAN HEART JOURNAL. vol. 40, 2643-2643.
Ramírez J, van Duijvenboden S, Aung N, Laguna P, Pueyo E, Tinker A, Lambiase PD, Orini M et al.(2019). Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. Circulation: Arrhythmia and Electrophysiology vol. 12, (10) e007549-e007549.
10.1161/CIRCEP.119.007549
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61114
Petersen S, Munroe P, Aung N, Fung K, Vargas J, Yang C, Cabrera CP, Warren H et al.(2019). Genome-wide analysis of left ventricular image-derived phenotypes identifies fourteen loci associated with cardiac morphogenesis and heart failure development. Circulation
10.1161/CIRCULATIONAHA.119.041161
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59778
Noordam R, Young WJ, Munroe PB(2019). Electrolytes and electrophysiology: What's next?. Aging vol. 11, (18) 7329-7330.
10.18632/aging.102267
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60958
Iniesta R, Campbell D, Venturini C, Faconti L, Singh S, Irvin MR, Cooper-DeHoff RM, Johnson JA et al.(2019). Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals. Hypertension vol. 74, (3) 614-622.
10.1161/HYPERTENSIONAHA.118.12177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59345
Singh S, Warren HR, Hiltunen TP, McDonough CW, El Rouby N, Salvi E, Wang Z, Garofalidou T et al.(2019). Genome-Wide Meta-Analysis of Blood Pressure Response to β<inf>1</inf>-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies). Journal of the American Heart Association vol. 8, (16)
10.1161/JAHA.119.013115
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60742
Cartwright JH, Aziz Q, Harmer SC, Thayyil S, Tinker A, Munroe PB(2019). Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function. Hum Mol Genet
10.1093/hmg/ddz198
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59560
Cabrera CP, Ng F, Nicholls HL, Gupta A, Barnes MR, Munroe PB, Caulfield MJ(2019). Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicated. Human Molecular Genetics vol. 28, (R2) R151-R161.
10.1093/hmg/ddz197
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61878
Sung YJ, De Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR et al.(2019). A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Human Molecular Genetics vol. 28, (15) 2615-2633.
10.1093/hmg/ddz070
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59202
Thomas AM, Cabrera CP, Finlay M, Lall K, Nobles M, Schilling RJ, Wood K, Mein CA et al.(2019). Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages. Physiol Genomics vol. 51, (8) 323-332.
10.1152/physiolgenomics.00012.2019
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59231
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2019). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x). Nature Genetics vol. 51, (7) 1191-1192.
10.1038/s41588-019-0447-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61615
Noordam R, Young WJ, Salman R, Kanters JK, van den Berg ME, van Heemst D, Lin HJ, Barreto SM et al.(2019). Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. Journal of the American College of Cardiology vol. 73, (24) 3118-3131.
10.1016/j.jacc.2019.03.519
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62235
van Setten J, Verweij N, Mbarek H, Niemeijer MN, Trompet S, Arking DE, Brody JA, Gandin I et al.(2019). Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics vol. 27, (6) 952-962.
10.1038/s41431-018-0295-z
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56172
De Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT et al.(2019). Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology vol. 188, (6) 1033-1054.
10.1093/aje/kwz005
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56171
Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI et al.(2019). Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics vol. 51, (4) 636-648.
10.1038/s41588-019-0378-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58835
Bastiaenen R, Nolte IM, Munroe PB, Riese H, Nelson C, O'Connor H, Gang Y, Warren HR et al.(2019). The narrow-sense and common single nucleotide polymorphism heritability of early repolarization. International Journal of Cardiology vol. 279, 135-140.
10.1016/j.ijcard.2018.09.119
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54484
Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL et al.(2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics vol. 51, (3) 452-469.
10.1038/s41588-018-0334-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56167
Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C et al.(2019). Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Molecular Psychiatry
10.1038/s41380-018-0313-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55829
Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP et al.(2019). Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Nature Genetics vol. 51, (1) 51-62.
10.1038/s41588-018-0303-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55066
Parn K, Pirinen M, Kals M, Magi R, Salomaa V, Boehnke M, Hall I, Stitziel N et al. (2018). Differences in the commonly used genotype imputation algorithms and their imputation accuracy estimates. Proceedings - IEEE 14th International Conference on eScience, e-Science 2018. 293-294.
10.1109/eScience.2018.00058
Brazel DM, Jiang Y, Hughey JM, Turcot V, Zhan X, Gong J, Batini C, Weissenkampen JD et al.(2018). Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Biological Psychiatry
10.1016/j.biopsych.2018.11.024
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57046
van Setten J, Brody JA, Jamshidi Y, Swenson BR, Butler AM, Campbell H, Del Greco FM, Evans DS et al.(2018). PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications vol. 9, (1)
10.1038/s41467-018-04766-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43005
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N et al.(2018). Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet vol. 50, (12) 1755-1755.
10.1038/s41588-018-0297-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56068
Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al.(2018). Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. Nature Communications vol. 9, (1)
10.1038/s41467-018-04148-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39943
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N et al.(2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics vol. 50, (10) 1412-1425.
10.1038/s41588-018-0205-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/47343
Ramirez J, Van Duijvenboden S, Laguna P, Pueyo E, Tinker A, Lambiase PD, Munroe PB, Orini M (2018). Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology. Computing in Cardiology. Conference: Computing in Cardiology (Maastricht, The Netherlands) from: 23/09/2018 to: 26/09/2018, vol. 2018-September,
10.22489/CinC.2018.039
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59557
PETERSEN SE, AUNG N, SANGHVI M, ZEMRAK F, LEE A, COOPER J, PAIVA J, Thomson R et al.(2018). Association between ambient air pollution and cardiac morpho-functional phenotypes: Insights from the UK Biobank population imaging study. Circulation
10.1161/CIRCULATIONAHA.118.034856
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43332
Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J et al.(2018). Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biology vol. 19, (1)
10.1186/s13059-018-1457-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42707
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ et al.(2018). Analysis of shared heritability in common disorders of the brain. Science vol. 360, (6395)
10.1126/science.aap8757
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42423
Ruderfer DM, Ripke S, McQuillin A, Boocock J, Stahl EA, Pavlides JMW, Mullins N, Charney AW et al.(2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell
10.1016/j.cell.2018.05.046
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39864
Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N et al.(2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS One vol. 13, (6) e0198166-e0198166.
10.1371/journal.pone.0198166
https://qmro.qmul.ac.uk/xmlui/handle/123456789/41963
Lin H, van Setten J, Smith AV, Bihlmeyer NA, Warren HR, Brody JA, Radmanesh F, Hall L et al.(2018). Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. Circulation. Genomic and precision medicine vol. 11, (5)
10.1161/CIRCGEN.117.002037
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39465
Smith AJP, Deloukas P, Munroe PB(2018). Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits. Physiol Genomics
10.1152/physiolgenomics.00028.2018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39304
Sung YJ, Winkler TW, de las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I et al.(2018). A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. American Journal of Human Genetics vol. 102, (3) 375-400.
10.1016/j.ajhg.2018.01.015
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35963
Orini M, Tinker A, Munroe PB, Lambiase PD(2018). Correction: Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort. PLoS One vol. 13, (2) e0193039-e0193039.
10.1371/journal.pone.0193039
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56173
McCarthy NS, Vangjeli C, Surendran P, Treumann A, Rooney C, Ho E, Sever P, Thom S et al.(2018). Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A<inf>2</inf> formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). Atherosclerosis vol. 269, 42-49.
10.1016/j.atherosclerosis.2017.12.013
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32223
Munroe PB, Jahangir SNS, Caulfield MJ(2018). Genetics and genomics of systemic hypertension. Cardiovascular Genetics and Genomics: Principles and Clinical Practice,
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45283
Bihlmeyer NA, Brody JA, Smith AV, Warren HR, Lin H, Isaacs A, Liu CT, Marten J et al.(2018). ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. Circulation. Genomic and precision medicine vol. 11, (1)
10.1161/CIRCGEN.117.001758
https://qmro.qmul.ac.uk/xmlui/handle/123456789/41884
Munroe PB, Warren HR(2018). Hypertension. Genomic and Precision Medicine: Cardiovascular Disease: Third Edition,
Munroe PB, Addison S, Abrams DJ, Sebire NJ, Cartwright J, Donaldson I, Cohen MM, Mein C et al.(2018). Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths. Circulation. Genomic and precision medicine vol. 11, (1)
10.1161/CIRCGEN.117.001817
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45703
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics vol. 50, (1) 26-35.
10.1038/s41588-017-0011-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34563
Ren M, Ng FL, Warren HR, Witkowska K, Baron M, Jia Z, Cabrera C, Zhang R et al.(2018). The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle. Human Molecular Genetics vol. 27, (1) 199-210.
10.1093/hmg/ddx375
https://qmro.qmul.ac.uk/xmlui/handle/123456789/30823
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C et al.(2017). Exome-wide association study of plasma lipids in &gt;300,000 individuals. Nature Genetics vol. 49, (12) 1758-1766.
10.1038/ng.3977
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28624
Warren H, Sun F, Stewart J, Broer L, Trompet S, Clarke H, Sitlani C, Noordam R et al. (2017). Large-scale genome-wide pharmacogenetic meta-analysis of blood pressure response to antihypertensive drugs. vol. 31, is. 10, pp. 659-659.
10.1038/jhh.2017.63
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28626
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N et al.(2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation: Cardiovascular Genetics vol. 10, (5)
10.1161/CIRCGENETICS.117.001778
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56729
Little L, Kraja AT, Cook JP, Warren HR, Newton-Cheh C, Munroe PB, Howson JMM, BP CE et al. (2017). New blood pressure associated loci identified in meta-analyses of 475,000 individuals using the Exome Chip. vol. 31, is. 10, pp. 665-666.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28627
Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P et al.(2017). Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet vol. 49, (10) 1558-1558.
10.1038/ng1017-1558a
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50805
Orini M, Tinker A, Munroe PB, Lambiase PD(2017). Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort. PLoS One vol. 12, (9) e0183732-e0183732.
10.1371/journal.pone.0183732
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34309
Wain LV, Vaez A, Jansen R, Joehanes R, Van Der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP et al.(2017). Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets from Blood and the Kidney. Hypertension vol. 70, (3) e4-e19.
10.1161/HYPERTENSIONAHA.117.09438
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26603
Munroe PB, Tinker A(2017). Heritability of resting heart rate and association with mortality in middle-aged and elderly twins. Heart vol. 104, (1) 6-7.
10.1136/heartjnl-2017-311657
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24967
Dale CE, Fatemifar G, Palmer TM, White J, Prieto-Merino D, Zabaneh D, Engmann JEL, Shah T et al.(2017). Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis. Circulation vol. 135, (24) 2373-2388.
10.1161/CIRCULATIONAHA.116.026560
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24949
Rao DC, Sung YJ, Winkler TW, Schwander K, Borecki I, Adrienne Cupples L, James Gauderman W, Rice K et al.(2017). Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals from 124 Cohorts: Design and Rationale. Circulation: Cardiovascular Genetics vol. 10, (3)
10.1161/CIRCGENETICS.116.001649
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59025
Wu Y-T, Luben R, Wareham N, Griffin S, Jones AP(2017). Weather, day length and physical activity in older adults: Cross-sectional results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Norfolk Cohort. PLoS One vol. 12, (5) e0177767-e0177767.
10.1371/journal.pone.0177767
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33695
Song C, Burgess S, Eicher JD, O'Donnell CJ, Johnson AD, Huang J, Sabater-Lleal M, Asselbergs FW et al.(2017). Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease. Journal of the American Heart Association vol. 6, (6)
10.1161/JAHA.116.004918
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25717
Cartwright J, Aziz Q, Harmer S, Tinker A, Munroe P (2017). Functional Studies of TRPM7-a Candidate Gene for Stillbirth?. FASEB JOURNAL. Conference: EB vol. 31,
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59037
Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X et al.(2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun vol. 8, 14977-14977.
10.1038/ncomms14977
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33363
MUNROE PB, Caulfield M, Stirrups K, van den Berg M, Warren H, Cabrera CP(2017). Discovery of novel heart rate-associated loci using the exome chip. Human Molecular Genetics
10.1093/hmg/ddx113
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22369
Munroe PB, Warren HR(2017). Hypertension. Genomic and Precision Medicine: Primary Care: Third Edition,
McLaughlin RL, Schijven D, Van Rheenen W, Van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A et al.(2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications vol. 8,
10.1038/ncomms14774
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45483
Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P et al.(2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet vol. 49, (3) 403-415.
10.1038/ng.3768
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19169
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature vol. 542, (7640) 186-190.
10.1038/nature21039
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23049
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A et al.(2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics vol. 49, (1) 27-35.
10.1038/ng.3725
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22706
Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR et al.(2016). A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. J Med Genet
10.1136/jmedgenet-2016-104112
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19162
Yaghootkar H, Bancks MP, Jones SE, McDaid A, Beaumont R, Donnelly L, Wood AR, Campbell A et al.(2016). Quantifying the extent to which index event biases influence large genetic association studies. Hum Mol Genet
10.1093/hmg/ddw433
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19060
Wang Y, Wu Z, Luo H, Peng J, Raelson J, Ehret GB, Munroe PB, Stoyanova E et al.(2016). The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility. Sci Rep vol. 6, 38976-38976.
10.1038/srep38976
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23213
Gregson JM, Freitag DF, Surendran P, Stitziel NO, Chowdhury R, Burgess S, Kaptoge S, Gao P et al.(2016). Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles. Eur J Prev Cardiol
10.1177/2047487316682186
https://qmro.qmul.ac.uk/xmlui/handle/123456789/21440
Hayat SA, Luben R, Dalzell N, Moore S, Anuj S, Matthews FE, Wareham N, Brayne C et al.(2016). Cross Sectional Associations between Socio-Demographic Factors and Cognitive Performance in an Older British Population: The European Investigation of Cancer in Norfolk (EPIC-Norfolk) Study. PLoS One vol. 11, (12) Article 0166779, e0166779-e0166779.
10.1371/journal.pone.0166779
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35025
Barban N, Jansen R, De Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF et al.(2016). Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nature Genetics vol. 48, (12) 1462-1472.
10.1038/ng.3698
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28806
Eppinga RN, Hagemeijer Y, Burgess S, Hinds DA, Stefansson K, Gudbjartsson DF, van Veldhuisen DJ, Munroe PB et al.(2016). Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality. Nat Genet vol. 48, (12) 1557-1563.
10.1038/ng.3708
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25995
Hibar DP, Westlye LT, Van Erp TGM, Rasmussen J, Leonardo CD, Faskowitz J, Haukvik UK, Hartberg CB et al.(2016). Subcortical volumetric abnormalities in bipolar disorder. Molecular Psychiatry vol. 21, (12) 1710-1716.
10.1038/mp.2015.227
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G et al.(2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications vol. 7, 13357-13357.
10.1038/ncomms13357
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19341
Leng Y, Cappuccio FP, Surtees PG, Luben R, Brayne C, Khaw KT(2016). Daytime napping, sleep duration and increased 8-year risk of type 2 diabetes in a British population. Nutrition, Metabolism and Cardiovascular Diseases vol. 26, (11) 996-1003.
10.1016/j.numecd.2016.06.006
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35043
Warren HR, van den Berg ME, van der Harst P, Verweij N, Eijgelsheim M, Stricker BH, Munroe PB, Grp CHARGECEKGW (2016). Discovery of Novel Loci Associated with Heart Rate from Exome Chip Analysis. GENETIC EPIDEMIOLOGY. Conference: International Genetic Epidemiology Society vol. 40, 670-670.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18150
Jepson RE, Warren HR, Syme HM, Elliott J, Munroe PB(2016). Uromodulin gene variants and their association with renal function and blood pressure in cats: a pilot study. J Small Anim Pract vol. 57, (11) 580-588.
10.1111/jsap.12582
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23567
Johnson EC, Bjelland DW, Howrigan DP, Abdellaoui A, Breen G, Borglum A, Cichon S, Degenhardt F et al.(2016). No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study. PLoS Genet vol. 12, (10) e1006343-e1006343.
10.1371/journal.pgen.1006343
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34346
Julian C, Lentjes MAH, Huybrechts I, Luben R, Wareham N, Moreno LA, Khaw K-T(2016). Fracture Risk in Relation to Serum 25-Hydroxyvitamin D and Physical Activity: Results from the EPIC-Norfolk Cohort Study. PLoS One vol. 11, (10) e0164160-e0164160.
10.1371/journal.pone.0164160
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34473
Warren HR, Surendran P, Manning AK, van den Berg ME, van der Harst P, Verweij N, Eijgelsheim M, Stricker BHC et al.(2016). Novel loci discovery for blood pressure and heart rate using the Exome chip. JOURNAL OF HUMAN HYPERTENSION vol. 30, (10) 653-653.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18151
van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I et al.(2016). 52 Genetic Loci Influencing Myocardial Mass. J Am Coll Cardiol vol. 68, (13) 1435-1448.
10.1016/j.jacc.2016.07.729
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16288
MUNROE PB(2016). Fifty-two genetic loci influencing myocardial mass. Journal of the American College of Cardiology
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13740
MUNROE PB(2016). Trans-ancestry meta-analyses identify novel rare and common variants associated with blood pressure and hypertension. Nature Genetics
10.1038/ng.3654
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13707
MUNROE PB(2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics
10.1038/ng.3667
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15563
Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE et al.(2016). Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Journal of Medical Genetics
10.1136/jmedgenet-2016-103966
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15127
van der Laan SW, Fall T, Soumaré A, Teumer A, Sedaghat S, Baumert J, Zabaneh D, van Setten J et al.(2016). Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. Journal of the American College of Cardiology vol. 68, (9) 934-945.
10.1016/j.jacc.2016.05.092
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19139
Pinnock C, Yip JLY, Khawaja AP, Luben R, Hayat S, Broadway DC, Foster PJ, Khaw K-T et al.(2016). Topical Beta-Blockers and Cardiovascular Mortality: Systematic Review and Meta-Analysis with Data from the EPIC-Norfolk Cohort Study. Ophthalmic Epidemiol vol. 23, (5) 277-284.
10.1080/09286586.2016.1213301
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33650
Basu N, Yang X, Luben RN, Whibley D, Macfarlane GJ, Wareham NJ, Khaw K-T, Myint PK(2016). Fatigue is associated with excess mortality in the general population: results from the EPIC-Norfolk study. BMC Med vol. 14, (1) 122-122.
10.1186/s12916-016-0662-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34468
Guo Y, Warren Andersen S, Shu X-O, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL et al.(2016). Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent. PLoS Med vol. 13, (8) e1002105-e1002105.
10.1371/journal.pmed.1002105
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34643
Kwok CS, Loke YK, Welch AA, Luben RN, Lentjes MAH, Boekholdt SM, Pfister R, Mamas MA et al.(2016). Habitual chocolate consumption and the risk of incident heart failure among healthy men and women. Nutrition, Metabolism and Cardiovascular Diseases vol. 26, (8) 722-734.
10.1016/j.numecd.2016.01.003
Kanoni S, Masca NGD, Stirrups KE, Varga TV, Warren HR, Scott RA, Southam L, Zhang W et al.(2016). Analysis with the exome array identifies multiple new independent variants in lipid loci. Human Molecular Genetics vol. 25, (18) ddw227-ddw227.
10.1093/hmg/ddw227
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14812
Opstelten JL, Beelen RMJ, Leenders M, Hoek G, Brunekreef B, van Schaik FDM, Siersema PD, Eriksen KT et al.(2016). Exposure to Ambient Air Pollution and the Risk of Inflammatory Bowel Disease: A European Nested Case-Control Study. Dig Dis Sci vol. 61, (10) 2963-2971.
10.1007/s10620-016-4249-4
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34435
Leng Y, Wainwright NWJ, Cappuccio FP, Surtees PG, Hayat S, Luben R, Brayne C, Khaw K-T(2016). Daytime napping and increased risk of incident respiratory diseases: symptom, marker, or risk factor?. Sleep Med vol. 23, 12-15.
10.1016/j.sleep.2016.06.012
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35026
Prins BP, Abbasi A, Wong A, Vaez A, Nolte I, Franceschini N, Stuart PE, Guterriez Achury J et al.(2016). Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. PLOS Medicine vol. 13, (6) e1001976-e1001976.
10.1371/journal.pmed.1001976
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13382
Bearden CE, Zandi P, Freimer NB(2016). Molecular Architecture and Neurobiology of Bipolar Disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry,
Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stancakova A et al.(2016). A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Science Translational Medicine vol. 8, (341) 341ra76-341ra76.
10.1126/scitranslmed.aad3744
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13116
Lessard S, Manning AK, Low-Kam C, Auer PL, Giri A, Graff M, Schurmann C, Yaghootkar H et al.(2016). Testing the role of predicted gene knockouts in human anthropometric trait variation. Human Molecular Genetics vol. 25, (10) 2082-2092.
10.1093/hmg/ddw055
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12772
Bodea CA, Neale BM, Ripke S, Daly MJ, Devlin B, Roeder K(2016). A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies. American Journal of Human Genetics vol. 98, (5) 857-868.
10.1016/j.ajhg.2016.02.025
Zhao Z, Wen W, Michailidou K, Bolla MK, Wang Q, Zhang B, Long J, Shu XO et al.(2016). Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry. Cancer Causes and Control vol. 27, (5) 679-693.
10.1007/s10552-016-0741-6
Hemerich D, Tragante V, Harakalova M, Mokry M, Kerstens H, Munroe PB, Asselbergs FW (2016). Fine mapping of blood pressure-related variants on epigenetic human data. European Journal of Clinical Investigation. Conference: 50th Annual Scientific Meeting of the European Society for Clinical Investigation (Paris, France) from: 27/04/2016 to: 29/04/2016, vol. 46, 120-120.
10.1111/eci.12603
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13739
Leusink M, Maitland-Van Der Zee AH, Ding B, Drenos F, Van Iperen EPA, Warren HR, Caulfield MJ, Cupples LA et al.(2016). A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering. Pharmacogenomics vol. 17, (6) 583-591.
10.2217/pgs.16.8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12771
Khawaja AP, Chan MPY, Yip JLY, Broadway DC, Garway-Heath DF, Luben R, Hayat S, Matthews FE et al.(2016). Retinal Nerve Fiber Layer Measures and Cognitive Function in the EPIC-Norfolk Cohort Study. Invest Ophthalmol Vis Sci vol. 57, (4) 1921-1926.
10.1167/iovs.16-19067
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33989
M'Rabet-Bensalah K, Aubert CE, Coslovsky M, Collet TH, Baumgartner C, Den Elzen WPJ, Luben R, Angelillo-Scherrer A et al.(2016). Thyroid dysfunction and anaemia in a large population-based study. Clinical Endocrinology vol. 84, (4) 627-631.
10.1111/cen.12994
Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S et al.(2016). Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics vol. 48, (4) 374-386.
10.1038/ng.3521
Fan Q, Verhoeven VJM, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Hohn R, Vitart V et al.(2016). Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nature Communications vol. 7,
10.1038/ncomms11008
Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J, Suvisaari J, Chheda H et al.(2016). Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nature Neuroscience vol. 19, (4) 571-577.
10.1038/nn.4267
Stoekenbroek RM, Matthijs Boekholdt S, Luben R, Kees Hovingh G, Zwinderman AH, Wareham NJ, Khaw KT, Peters RJG(2016). Heterogeneous impact of classic atherosclerotic risk factors on different arterial territories: The EPIC-Norfolk prospective population study. European Heart Journal vol. 37, (11) 880-889.
10.1093/eurheartj/ehv630
Myint PK, Hawkins KR, Clark AB, Luben RN, Wareham NJ, Khaw KT, Wilson AM(2016). Long-term mortality of hospitalized pneumonia in the EPIC-Norfolk cohort. Epidemiology and Infection vol. 144, (4) 803-809.
10.1017/S0950268815001971
Keevil VL, Cooper AJM, Wijndaele K, Luben R, Wareham NJ, Brage S, Khaw KT(2016). Objective Sedentary Time, Moderate-to-Vigorous Physical Activity, and Physical Capability in a British Cohort. Medicine and Science in Sports and Exercise vol. 48, (3) 421-429.
10.1249/MSS.0000000000000785
Easton DF, Lesueur F, Decker B, Michailidou K, Li J, Allen J, Luccarini C, Pooley KA et al.(2016). No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: Implications for gene panel testing. Journal of Medical Genetics vol. 53, (5) 298-309.
10.1136/jmedgenet-2015-103529
Franke B, van Hulzen KJE, Arias-Vasquez A, Bralten J, Hoogman M, Klein M, van Donkelaar MMJ, Hakobjan MMH et al.(2016). Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept. Nature Neuroscience vol. 19, (3) 420-431.
10.1038/nn.4228
Diver LA, MacKenzie SM, Fraser R, McManus F, Freel EM, Alvarez-Madrazo S, McClure JD, Friel EC et al.(2016). Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus. Hypertension vol. 67, (4) 724-732.
10.1161/hypertensionaha.115.06925
Pagani L, Clair PAS, Teshiba TM, Service SK, Fears SC, Araya C, Araya X, Bejarano J et al.(2016). Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder. Proceedings of the National Academy of Sciences of the United States of America vol. 113, (6) E754-E761.
10.1073/pnas.1513525113
Thompson DJ, O'Mara TA, Glubb DM, Painter JN, Cheng T, Folkerd E, Doody D, Dennis J et al.(2016). CYP19A1 fine-mapping and Mendelian randomization: Estradiol is causal for endometrial cancer. Endocrine-Related Cancer vol. 23, (2) 77-91.
10.1530/ERC-15-0386
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A et al.(2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications vol. 7,
10.1038/ncomms10023
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12758
Racine A, Carbonnel F, Chan SSM, Hart AR, Bas Bueno-De-Mesquita H, Oldenburg B, Van Schaik FDM, Tjønneland A et al.(2016). Dietary Patterns and Risk of Inflammatory Bowel Disease in Europe: Results from the EPIC Study. Inflammatory Bowel Diseases vol. 22, (2) 345-354.
10.1097/MIB.0000000000000638
Berkemeyer K, Wijndaele K, White T, Cooper AJM, Luben R, Westgate K, Griffin SJ, Khaw KT et al.(2016). The descriptive epidemiology of accelerometer-measured physical activity in older adults. International Journal of Behavioral Nutrition and Physical Activity vol. 13, (1)
10.1186/s12966-015-0316-z
Noor NM, Banim PJR, Luben RN, Khaw KT, Hart AR(2016). Investigating physical activity in the etiology of pancreatic cancer : The age at which this is measured is important and is independent of body mass index. Pancreas vol. 45, (3) 388-393.
10.1097/MPA.0000000000000494
Turner TR, Coetzer WG, Schmitt CA, Lorenz JG, Freimer NB, Grobler JP(2016). Localized population divergence of vervet monkeys (Chlorocebus spp.) in South Africa: Evidence from mtDNA. American Journal of Physical Anthropology vol. 159, (1) 17-30.
10.1002/ajpa.22825
Luben R, Hayat S, Wareham N, Khaw KT(2016). Predicting admissions and time spent in hospital over a decade in a population-based record linkage study: The EPIC-Norfolk cohort. BMJ Open vol. 6, (1)
10.1136/bmjopen-2015-009461
Yaghootkar H, Bancks MP, Jones SE, McDaid AF, Beaumont R, Donnelly L, Wood AR, Campbell A et al. (2016). Quantifying the Extent to Which Index Event Biases Influence Large Genetic Association Studies. HUMAN HEREDITY. vol. 81, 214-214.
Hayhoe RPG, Lentjes MAH, Luben RN, Khaw KT, Welch AA(2016). Reply to W Lin and R Wang. American Journal of Clinical Nutrition vol. 103, (1) 290-291.
10.3945/ajcn.115.122291
Bailey AL, Lauck M, Sibley SD, Friedrich TC, Kuhn JH, Freimer NB, Jasinska AJ, Phillips-Conroy JE et al.(2016). Zoonotic potential of simian arteriviruses. Journal of Virology vol. 90, (2) 630-635.
10.1128/JVI.01433-15
Finck H, Hart AR, Lentjes MAH, Jennings A, Luben RN, Khaw KT, Welch AA(2015). Cross-sectional and prospective associations between dietary and plasma Vitamin C, heel bone ultrasound, and fracture risk in men and women in the European Prospective Investigation into Cancer in Norfolk cohort. American Journal of Clinical Nutrition vol. 102, (6) 1416-1424.
10.3945/ajcn.115.111971
Reppe S, Wang Y, Thompson WK, McEvoy LK, Schork AJ, Zuber V, LeBlanc M, Bettella F et al.(2015). Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci. PLoS ONE vol. 10, (12)
10.1371/journal.pone.0144531
Warren WC, Jasinska AJ, García-Pérez R, Svardal H, Tomlinson C, Rocchi M, Archidiacono N, Capozzi O et al.(2015). The genome of the vervet (Chlorocebus æthiops sabæus). Genome Research vol. 25, (12) 1921-1933.
10.1101/gr.192922.115
Gallo V, Brayne C, Forsgren L, Barker RA, Petersson J, Hansson O, Lindqvist D, Ruffmann C et al.(2015). Parkinson's Disease Case Ascertainment in the EPIC Cohort: The NeuroEPIC4PD Study. Neurodegenerative Diseases vol. 15, (6) 331-338.
10.1159/000381857
https://qmro.qmul.ac.uk/xmlui/handle/123456789/8628
Kuhnle GGC, Tasevska N, Lentjes MAH, Griffin JL, Sims MA, Richardson L, Aspinall SM, Mulligan AA et al.(2015). Association between sucrose intake and risk of overweight and obesity in a prospective sub-cohort of the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk). Public Health Nutrition vol. 18, (15) 2815-2824.
10.1017/S1368980015000300
Warren HR, Surendran P, Drenos F, Young R, Cook JP, Manning AK, Grarup N, Sim X et al. (2015). Investigating the Association of Rare Genetic Variants with Blood Pressure traits. GENETIC EPIDEMIOLOGY. vol. 39, 591-591.
Rodríguez RL, Cramer JD, Schmitt CA, Gaetano TJ, Grobler JP, Freimer NB, Turner TR(2015). Adult age confounds estimates of static allometric slopes in a vertebrate. Ethology Ecology and Evolution vol. 27, (4) 412-421.
10.1080/03949370.2014.986767
de Leeuw C, Goudriaan A, Smit AB, Yu D, Mathews CA, Scharf JM, Verheijen MHG, Posthuma D et al.(2015). Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis. European Journal of Human Genetics vol. 23, (11) 1519-1522.
10.1038/ejhg.2015.22
Haut KM, Karlsgodt KH, Bilder RM, Congdon E, Freimer NB, London ED, Sabb FW, Ventura J et al.(2015). Memory systems in schizophrenia: Modularity is preserved but deficits are generalized. Schizophrenia Research vol. 168, (1-2) 223-230.
10.1016/j.schres.2015.08.014
Hong Lee S, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AAE, Ripke S, Andreassen OA, Frisell T et al.(2015). New data and an old puzzle: The negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology vol. 44, (5) 1706-1721.
10.1093/ije/dyv136
Wain LV, Shrine N, Miller S, Jackson VE, Ntalla I, Artigas MS, Billington CK, Kheirallah AK et al.(2015). Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank. The Lancet Respiratory Medicine vol. 3, (10) 769-781.
10.1016/S2213-2600(15)00283-0
Warren H, Sever P, Poulter N, Stanton A, Caulfield M, Munroe P(2015). Pharmacogenetic GWAS meta-analysis of response to antihypertensive drugs. JOURNAL OF HUMAN HYPERTENSION vol. 29, (10) 627-627.
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T et al.(2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS genetics vol. 11, (10)
10.1371/journal.pgen.1005378
Lindström S, Thompson DJ, Paterson AD, Li J, Gierach GL, Scott C, Stone J, Douglas JA et al.(2015). Erratum: Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk (Nature Communications (2014) 5:5303 (DOI:10.1038/ncomms6303)). Nature Communications vol. 6,
10.1038/ncomms9358
Munroe PB, Tinker A(2015). Genome-wide association studies and contribution to cardiovascular physiology. Physiological Genomics vol. 47, (9) 365-375.
10.1152/physiolgenomics.00004.2015
https://qmro.qmul.ac.uk/xmlui/handle/123456789/8221
Rudolph A, Fasching PA, Behrens S, Eilber U, Bolla MK, Wang Q, Thompson D, Czene K et al.(2015). A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density. Breast Cancer Research vol. 17, (1)
10.1186/s13058-015-0625-9
Kwok CS, Boekholdt SM, Lentjes MAH, Loke YK, Luben RN, Yeong JK, Wareham NJ, Myint PK et al.(2015). Habitual chocolate consumption and risk of cardiovascular disease among healthy men and women. Heart vol. 101, (16) 1279-1287.
10.1136/heartjnl-2014-307050
Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C et al.(2015). Directional dominance on stature and cognition in diverse human populations. Nature vol. 523, (7561) 459-462.
10.1038/nature14618
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12751
Bain LKM, Myint PK, Jennings A, Lentjes MAH, Luben RN, Khaw KT, Wareham NJ, Welch AA(2015). The relationship between dietary magnesium intake, stroke and its major risk factors, blood pressure and cholesterol, in the EPIC-Norfolk cohort. International Journal of Cardiology vol. 196, 108-114.
10.1016/j.ijcard.2015.05.166
Yip JLY, Khawaja AP, Chan MPY, Broadway DC, Peto T, Tufail A, Luben R, Hayat S et al.(2015). Cross sectional and longitudinal associations between cardiovascular risk factors and age related macular degeneration in the EPICNorfolk eye study. PLoS ONE vol. 10, (7)
10.1371/journal.pone.0132565
Vogiatzoglou A, Mulligan AA, Bhaniani A, Lentjes MAH, McTaggart A, Luben RN, Heiss C, Kelm M et al.(2015). Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). Free Radical Biology and Medicine vol. 84, 1-10.
10.1016/j.freeradbiomed.2015.03.005
Huang YS, Ramensky V, Service SK, Jasinska AJ, Jung Y, Choi OW, Cantor RM, Juretic N et al.(2015). Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits. BMC Biology vol. 13, (1)
10.1186/s12915-015-0152-2
Stone J, Thompson DJ, Dos Santos Silva I, Scott C, Tamimi RM, Lindstrom S, Kraft P, Hazra A et al.(2015). Novel associations between common breast cancer susceptibility variants and risk-predicting mammographic density measures. Cancer Research vol. 75, (12) 2457-2467.
10.1158/0008-5472.CAN-14-2012
Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N et al.(2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry vol. 20, (5) 647-656.
10.1038/mp.2014.107
Vogiatzoglou A, Mulligan AA, Lentjes MAH, Luben RN, Spencer JPE, Schroeter H, Khaw KT, Kuhnle GGC(2015). Flavonoid intake in European adults (18 to 64 Years). PLoS ONE vol. 10, (5)
10.1371/journal.pone.0128132
Ahmadi-Abhari S, Kaptoge S, Luben RN, Wareham NJ, Khaw KT(2015). Longitudinal association of C-reactive protein and Haemoglobin A<inf>1c</inf> over 13 years: The European Prospective Investigation into Cancer - Norfolk study. Cardiovascular Diabetology vol. 14, (1)
10.1186/s12933-015-0224-1
Lentjes MAH, Welch AA, Keogh RH, Luben RN, Khaw KT(2015). Opposites don't attract: High spouse concordance for dietary supplement use in the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study. Public Health Nutrition vol. 18, (6) 1060-1066.
10.1017/S1368980014001396
Mavaddat N, Pharoah PDP, Michailidou K, Tyrer J, Brook MN, Bolla MK, Wang Q, Dennis J et al.(2015). Prediction of breast cancer risk based on profiling with common genetic variants. Journal of the National Cancer Institute vol. 107, (5)
10.1093/jnci/djv036
Keevil VL, Wijndaele K, Luben R, Sayer AA, Wareham NJ, Khaw KT(2015). Television viewing, walking speed, and grip strength in a prospective cohort study. Medicine and Science in Sports and Exercise vol. 47, (4) 735-742.
10.1249/MSS.0000000000000453
Cooper AJM, Sharp SJ, Luben RN, Khaw KT, Wareham NJ, Forouhi NG(2015). The association between a biomarker score for fruit and vegetable intake and incident type 2 diabetes: The EPIC-Norfolk study. European Journal of Clinical Nutrition vol. 69, (4) 449-454.
10.1038/ejcn.2014.246
Hirschtritt ME, Lee PC, Pauls DL, Dion Y, Grados MA, Illmann C, King RA, Sandor P et al.(2015). Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in tourette syndrome. JAMA Psychiatry vol. 72, (4) 325-333.
10.1001/jamapsychiatry.2014.2650
Huffman JE, Albrecht E, Teumer A, Mangino M, Kapur K, Johnson T, Kutalik Z, Pirastu N et al.(2015). Modulation of genetic associations with serum urate levels by body-mass-index in humans. PLoS ONE vol. 10, (3)
10.1371/journal.pone.0119752
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7347
Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C et al.(2015). A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension. PLoS Genetics vol. 11, (3)
10.1371/journal.pgen.1005035
Leng Y, Cappuccio FP, Wainwright NWJ, Surtees PG, Luben R, Brayne C, Khaw KT(2015). Sleep duration and risk of fatal and nonfatal stroke: A prospective study and meta-analysis. Neurology vol. 84, (11) 1072-1079.
10.1212/WNL.0000000000001371
Ligthart S, De Vries PS, Uitterlinden AG, Hofman A, Franco OH, Chasman DI, Dehghan A, Dupuis J et al.(2015). Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein. PLoS ONE vol. 10, (3)
10.1371/journal.pone.0118859
Bulik-Sullivan B, Loh PR, Finucane HK, Ripke S, Yang J, Patterson N, Daly MJ, Price AL et al.(2015). LD score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics vol. 47, (3) 291-295.
10.1038/ng.3211
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S et al.(2015). Genetic studies of body mass index yield new insights for obesity biology. Nature vol. 518, (7538) 197-206.
10.1038/nature14177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6989
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH et al.(2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature vol. 518, (7538) 187-196.
10.1038/nature14132
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7200
Lei J, Rudolph A, Moysich KB, Rafiq S, Behrens S, Goode EL, Pharoah PPD, Seibold P et al.(2015). Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy. Breast Cancer Research vol. 17, (1)
10.1186/s13058-015-0522-2
Maier R, Moser G, Chen GB, Ripke S, Coryell W, Potash JB, Scheftner WA, Shi J et al.(2015). Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. American Journal of Human Genetics vol. 96, (2) 283-294.
10.1016/j.ajhg.2014.12.006
O'Dushlaine C, Rossin L, Lee PH, Duncan L, Parikshak NN, Newhouse S, Ripke S, Neale BM et al.(2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. NATURE NEUROSCIENCE vol. 18, (2) 199-209.
10.1038/nn.3922
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7547
Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2015). Inverse association between bone mineral density and risk of aortic stenosis in men and women in EPIC-Norfolk prospective study. International Journal of Cardiology vol. 178, 29-30.
10.1016/j.ijcard.2014.10.065
Yip JLY, Khawaja AP, Chan MPY, Broadway DC, Peto T, Luben R, Hayat S, Bhaniani A et al.(2015). Area deprivation and age related macular degeneration in the EPIC-Norfolk Eye Study. Public Health vol. 129, (2) 103-109.
10.1016/j.puhe.2014.10.012
Saleheen D, Scott R, Javad S, Zhao W, Rodrigues A, Picataggi A, Lukmanova D, Mucksavage ML et al.(2015). Association of HDL cholesterol efflux capacity with incident coronary heart disease events: A prospective case-control study. The Lancet Diabetes and Endocrinology vol. 3, (7) 507-513.
10.1016/S2213-8587(15)00126-6
Fears SC, Schür R, Sjouwerman R, Service SK, Araya C, Araya X, Bejarano J, Knowles E et al.(2015). Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder. Brain vol. 138, (7) 2087-2102.
10.1093/brain/awv106
Hayat SA, Luben R, Moore S, Dalzell N, Bhaniani A, Anuj S, Matthews FE, Wareham N et al.(2015). Cognitive function in a general population of men and women: A cross sectional study in the European Investigation of Cancer-Norfolk cohort (EPIC-Norfolk). BMC Geriatrics vol. 14, (1)
10.1186/1471-2318-14-142
Lentjes MAH, Mulligan AA, Welch AA, Bhaniani A, Luben RN, Khaw KT(2015). Contribution of cod liver oil-related nutrients (vitamins A, D, E and eicosapentaenoic acid and docosahexaenoic acid) to daily nutrient intake and their associations with plasma concentrations in the EPIC-Norfolk cohort. Journal of Human Nutrition and Dietetics vol. 28, (6) 568-582.
10.1111/jhn.12271
Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P et al.(2015). Cross-disorder genome-wide analyses suggest a complex genetic relationship between tourette's syndrome and OCD. American Journal of Psychiatry vol. 172, (1) 82-93.
10.1176/appi.ajp.2014.13101306
Hayhoe RPG, Lentjes MAH, Luben RN, Khaw KT, Welch AA(2015). Dietary magnesium and potassium intakes and circulating magnesium are associated with heel bone ultrasound attenuation and osteoporotic fracture risk in the EPIC-Norfolk cohort study. American Journal of Clinical Nutrition vol. 102, (2) 376-384.
10.3945/ajcn.114.102723
Yousaf N, Low WY, Onipinla A, Mein C, Caulfield M, Munroe PB, Chernajovsky Y(2015). Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines. Clinical and Experimental Immunology vol. 180, (2) 289-304.
10.1111/cei.12575
Cabrera CP, Ng FL, Warren HR, Barnes MR, Munroe PB, Caulfield MJ(2015). Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics. Wiley Interdisciplinary Reviews: Systems Biology and Medicine vol. 7, (2) 73-90.
10.1002/wsbm.1290
Monsivais P, Scarborough P, Lloyd T, Mizdrak A, Luben R, Mulligan AA, Wareham NJ, Woodcock J(2015). Greater accordance with the dietary approaches to stop hypertension dietary pattern is associated with lower diet-related greenhouse gas production but higher dietary costs in the United Kingdom. American Journal of Clinical Nutrition vol. 102, (1) 138-145.
10.3945/ajcn.114.090639
Lachman S, Peters RJG, Lentjes MAH, Mulligan AA, Luben RN, Wareham NJ, Khaw KT, Boekholdt SM(2015). Ideal cardiovascular health and risk of cardiovascular events in the EPIC-Norfolk prospective population study. European Journal of Preventive Cardiology vol. 23, (9) 986-994.
10.1177/2047487315602015
Kapusinszky B, Mulvaney U, Jasinska AJ, Deng X, Freimer N, Delwart E(2015). Local virus extinctions following a host population bottleneck. Journal of Virology vol. 89, (16) 8152-8161.
10.1128/JVI.00671-15
Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR et al.(2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics vol. 97, (4) 576-592.
10.1016/j.ajhg.2015.09.001
Pfister R, Brägelmann J, Michels G, Wareham NJ, Luben R, Khaw KT(2015). Performance of the CHARGE-AF risk model for incident atrial fibrillation in the EPIC Norfolk cohort. European Journal of Preventive Cardiology vol. 22, (7) 932-939.
10.1177/2047487314544045
Warren H, Sever P, Poulter N, Stantont A, Caulfield M, Munroe P (2015). Pharmacogenetic Meta-Analysis of Response to Antihypertensive Drugs within ASCOT. HUMAN HEREDITY. vol. 79, 49-49.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7585
Darabi H, McCue K, Beesley J, Michailidou K, Nord S, Kar S, Humphreys K, Thompson D et al.(2015). Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression. American Journal of Human Genetics vol. 97, (1) 22-34.
10.1016/j.ajhg.2015.05.002
Khaw KT, Luben R, Wareham N(2015). Reply to WB grant. American Journal of Clinical Nutrition vol. 102, (1) 230-231.
10.3945/ajcn.114.102962
Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2015). Reply: The Importance of Ventricular-Vascular Uncoupling. JACC: Heart Failure vol. 3, (1) 95-96.
10.1016/j.jchf.2014.07.004
Chaker L, Baumgartner C, Den Elzen WPJ, Ikram MA, Blum MR, Collet TH, Bakker SJL, Dehghan A et al.(2015). Subclinical hypothyroidism and the risk of stroke events and fatal stroke: An individual participant data analysis. Journal of Clinical Endocrinology and Metabolism vol. 100, (6) 2181-2191.
10.1210/jc.2015-1438
Blum MR, Bauer DC, Collet TH, Fink HA, Cappola AR, Da Costa BR, Wirth CD, Peeters RP et al.(2015). Subclinical thyroid dysfunction and fracture risk a meta-analysis. JAMA - Journal of the American Medical Association vol. 313, (20) 2055-2065.
10.1001/jama.2015.5161
Fagerholm R, Schmidt MK, Khan S, Rafiq S, Tapper W, Aittomäki K, Greco D, Heikkinen T et al.(2015). The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients. Oncotarget vol. 6, (10) 7390-7407.
10.18632/oncotarget.3506
Rodríguez RL, Cramer JD, Schmitt CA, Gaetano TJ, Grobler JP, Freimer NB, Turner TR(2015). The static allometry of sexual and nonsexual traits in vervet monkeys. Biological Journal of the Linnean Society vol. 114, (3) 527-537.
10.1111/bij.12440
Myint PK, Fox C, Kwok CS, Luben RN, Wareham NJ, Khaw KT(2015). Total anticholinergic burden and risk of mortality and cardiovascular disease over 10 years in 21,636 middle-aged and older men and women of EPIC-norfolk prospective population study. Age and Ageing vol. 44, (2) 219-225.
10.1093/ageing/afu185
Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY et al.(2014). FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Human molecular genetics vol. 23, (25) 6961-6972.
10.1093/hmg/ddu411
Pfister R, Michels G, Brägelmann J, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2014). Plasma vitamin C and risk of hospitalisation with diagnosis of atrial fibrillation in men and women in EPIC-Norfolk prospective study. International Journal of Cardiology vol. 177, (3) 830-835.
10.1016/j.ijcard.2014.11.016
Holmes MV, Frikke-Schmidt R, Melis D, Luben R, Asselbergs FW, Boer JMA, Cooper J, Palmen J et al.(2014). A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease. Atherosclerosis vol. 237, (1) 5-12.
10.1016/j.atherosclerosis.2014.07.038
Yaghootkar H, Scott RA, White CC, Zhang W, Speliotes E, Munroe PB, Ehret GB, Bis JC et al.(2014). Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes. Diabetes vol. 63, (12) 4369-4377.
10.2337/db14-0318
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12780
McCarthy NS, Vangjeli C, Cavalleri GL, Delanty N, Shianna KV, Surendran P, O'Brien E, Munroe PB et al.(2014). Two further blood pressure loci identified in ion channel genes with a gene-centric approach. Circ Cardiovasc Genet vol. 7, (6) 873-879.
10.1161/CIRCGENETICS.113.000190
Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J et al.(2014). MicroRNA related polymorphisms and breast cancer risk. PLoS ONE vol. 9, (11)
10.1371/journal.pone.0109973
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K et al.(2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics vol. 46, (11) 1173-1186.
10.1038/ng.3097
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K et al.(2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet vol. 46, (11) 1173-1186.
10.1038/ng.3097
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6379
Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K et al.(2014). Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun vol. 5,
10.1038/ncomms6068
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6802
Lindström S, Thompson DJ, Paterson AD, Li J, Gierach GL, Scott C, Stone J, Douglas JA et al.(2014). Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk. Nature Communications vol. 5,
10.1038/ncomms6303
Lentjes MAH, Welch AA, Mulligan AA, Luben RN, Wareham NJ, Khaw KT(2014). Cod liver oil supplement consumption and health: Cross-sectional results from the EPIC-Norfolk cohort study. Nutrients vol. 6, (10) 4320-4337.
10.3390/nu6104320
Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N et al.(2014). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry
10.1038/mp.2014.107
Myint PK, Kwok CS, Luben RN, Wareham NJ, Khaw KT(2014). Body fat percentage, body mass index and waist-to-hip ratio as predictors of mortality and cardiovascular disease. Heart vol. 100, (20) 1613-1619.
10.1136/heartjnl-2014-305816
Shohaimi S, Boekholdt MS, Luben R, Wareham NJ, Khaw KT(2014). Distribution of lipid parameters according to different socio-economic indicators- the EPIC-Norfolk prospective population study. BMC Public Health vol. 14, (1)
10.1186/1471-2458-14-782
Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ et al.(2014). Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet vol. 46, (8) 826-836.
10.1038/ng.3014
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13708
Sotos-Prieto M, Luben R, Khaw KT, Wareham NJ, Forouhi NG(2014). The association between Mediterranean Diet Score and glucokinase regulatory protein gene variation on the markers of cardiometabolic risk: An analysis in the European Prospective Investigation into Cancer (EPIC)-Norfolk study. British Journal of Nutrition vol. 112, (1) 122-131.
10.1017/S0007114514000580
Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Xiangjun GU, Smith AV et al.(2014). Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. American Journal of Human Genetics vol. 95, (1) 49-65.
10.1016/j.ajhg.2014.06.002
Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV et al.(2014). Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet vol. 95, (1) 49-65.
10.1016/j.ajhg.2014.06.002
Nicodemus KK, Hargreaves A, Morris D, Anney R, Gill M, Corvin A, Donohoe G, Ripke S et al.(2014). Variability inworking memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway. JAMA Psychiatry vol. 71, (7) 778-785.
10.1001/jamapsychiatry.2014.528
Li J, Lindström LS, Foo JN, Rafiq S, Schmidt MK, Pharoah PDP, Michailidou K, Dennis J et al.(2014). 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy. Nature Communications vol. 5,
10.1038/ncomms5051
Addison S, Munroe P, Mein C, Cohen M, Fowler D, Sebire NJ, Peebles D, Taylor A et al.(2014). 8.2 cardiac ion channelopathies in unexplained stillbirths. Arch Dis Child Fetal Neonatal Ed vol. 99 Suppl 1,
10.1136/archdischild-2014-306576.31
Leng Y, Wainwright NWJ, Cappuccio FP, Surtees PG, Hayat S, Luben R, Brayne C, Khaw KT(2014). Daytime napping and the risk of all-cause and cause-specific mortality: A 13-year follow-up of a British population. American Journal of Epidemiology vol. 179, (9) 1115-1124.
10.1093/aje/kwu036
Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F et al.(2014). Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. HUMAN MOLECULAR GENETICS vol. 23, (9) 2498-2510.
10.1093/hmg/ddt626
Vogiatzoglou A, Mulligan AA, Luben RN, Lentjes MAH, Heiss C, Kelm M, Merx MW, Spencer JPE et al.(2014). Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union. British Journal of Nutrition vol. 111, (8) 1463-1473.
10.1017/S0007114513003930
Gaetano TJ, Danzy J, Mtshali MS, Theron N, Schmitt CA, Paul Grobler J, Freimer N, Turner TR(2014). Mapping correlates of parasitism in wild South African vervet monkeys (Chlorocebus aethiops). South African Journal of Wildlife Research vol. 44, (1) 56-70.
10.3957/056.044.0105
Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T et al.(2014). Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet vol. 94, (3) 349-360.
10.1016/j.ajhg.2013.12.016
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7839
Vogiatzoglou A, Heuer T, Mulligan AA, Lentjes MAH, Luben RN, Kuhnle GGC(2014). Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II). European Journal of Nutrition vol. 53, (2) 635-643.
10.1007/s00394-013-0572-0
Yip JLY, Khawaja AP, Broadway D, Luben R, Hayat S, Dalzell N, Bhaniani A, Wareham N et al.(2014). Visual acuity, self-reported vision and falls in the EPIC-Norfolk Eye study. British Journal of Ophthalmology vol. 98, (3) 377-382.
10.1136/bjophthalmol-2013-304179
Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT et al.(2014). A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. Journal of Medical Genetics vol. 51, (2) 122-131.
10.1136/jmedgenet-2013-102064
Lentjes MAH, McTaggart A, Mulligan AA, Powell NA, Parry-Smith D, Luben RN, Bhaniani A, Welch AA et al.(2014). Dietary intake measurement using 7Â d diet diaries in British men and women in the European prospective investigation into cancer-norfolk study: A focus on methodological issues. British Journal of Nutrition vol. 111, (3) 516-526.
10.1017/S0007114513002754
Myint PK, Clark AB, Kwok CS, Loke YK, Yeong JKY, Luben RN, Wareham NJ, Khaw KT(2014). Bone mineral density and incidence of stroke european prospective investigation into cancer-norfolk population-based study, systematic review, and meta-analysis. Stroke vol. 45, (2) 373-382.
10.1161/STROKEAHA.113.002999
Ahmadi-Abhari S, Luben RN, Powell N, Bhaniani A, Chowdhury R, Wareham NJ, Forouhi NG, Khaw KT(2014). Dietary intake of carbohydrates and risk of type 2 diabetes: The European Prospective Investigation into Cancer-Norfolk study. British Journal of Nutrition vol. 111, (2) 342-352.
10.1017/S0007114513002298
Mulligan AA, Luben RN, Bhaniani A, Parry-Smith DJ, O'Connor L, Khawaja AP, Forouhi NG, Khaw KT(2014). A new tool for converting food frequency questionnaire data into nutrient and food group values: FETA research methods and availability. BMJ Open vol. 4, (3)
10.1136/bmjopen-2013-004503
Yip JLY, Luben R, Hayat S, Khawaja AP, Broadway DC, Wareham N, Khaw KT, Foster PJ(2014). Area deprivation, individual socioeconomic status and low vision in the EPIC-Norfolk eye study. Journal of Epidemiology and Community Health vol. 68, (3) 204-210.
10.1136/jech-2013-203265
Chan SSM, Luben R, Olsen A, Tjonneland A, Kaaks R, Lindgren S, Grip O, Bergmann MM et al.(2014). Association between high dietary intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid and reduced risk of Crohn's disease. Alimentary Pharmacology and Therapeutics vol. 39, (8) 834-842.
10.1111/apt.12670
Ripke S, Neale BM, Corvin A, Walters JTR, Farh KH, Holmans PA, Lee P, Bulik-Sullivan B et al.(2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature vol. 511, (7510) 421-427.
10.1038/nature13595
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23686
Yates M, Cheong E, Luben R, Igali L, Fitzgerald R, Khaw KT, Hart A(2014). Body mass index, smoking, and alcohol and risks of Barrett's esophagus and esophageal adenocarcinoma: A UK prospective cohort study. Digestive Diseases and Sciences vol. 59, (7) 1552-1559.
10.1007/s10620-013-3024-z
Chan SSM, Luben R, Van Schaik F, Oldenburg B, Bueno-De-Mesquita HB, Hallmans G, Karling P, Lindgren S et al.(2014). Carbohydrate intake in the etiology of Crohn's disease and ulcerative colitis. Inflammatory Bowel Diseases vol. 20, (11) 2013-2021.
10.1097/MIB.0000000000000168
Hayat SA, Luben R, Keevil VL, Moore S, Dalzell N, Bhaniani A, Khawaja AP, Foster P et al.(2014). Cohort profile: A prospective cohort study of objective physical and cognitive capability and visual health in an ageing population of men and women in Norfolk (EPIC-Norfolk 3). International Journal of Epidemiology vol. 43, (4) 1063-1072.
10.1093/ije/dyt086
McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G et al.(2014). Copy number variation in obsessive-compulsive disorder and tourette syndrome: A cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry vol. 53, (8) 910-919.
10.1016/j.jaac.2014.04.022
Keevil VL, Luben R, Dalzell N, Hayat S, Sayer AA, Wareham NJ, Khaw KT(2014). Cross-sectional associations between different measures of obesity and muscle strength in men and women in a British cohort study. Journal of Nutrition, Health and Aging vol. 19, (1) 3-11.
10.1007/s12603-014-0492-6
Leng Y, Ahmadi-Abhari S, Wainwright NWJ, Cappuccio FP, Surtees PG, Luben R, Brayne C, Khaw KT(2014). Daytime napping, sleep duration and serum C reactive protein: A population-based cohort study. BMJ Open vol. 4, (11)
10.1136/bmjopen-2014-006071
White CN, Congdon E, Mumford JA, Karlsgodt KH, Sabb FW, Freimer NB, London ED, Cannon TD et al.(2014). Decomposing Decision Components in the Stop-signal Task: A Model-based Approach to Individual Differences in Inhibitory Control. Journal of Cognitive Neuroscience vol. 26, (8) 1601-1614.
10.1162/jocn_a_00567
De Silva PSA, Luben R, Shrestha SS, Khaw KT, Hart AR(2014). Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: A prospective cohort study using 7-day food diaries. European Journal of Gastroenterology and Hepatology vol. 26, (1) 11-18.
10.1097/MEG.0b013e328365c372
O'Connor LM, Lentjes MAH, Luben RN, Khaw KT, Wareham NJ, Forouhi NG(2014). Dietary dairy product intake and incident type 2 diabetes: A prospective study using dietary data from a 7-day food diary. Diabetologia vol. 57, (5) 909-917.
10.1007/s00125-014-3176-1
Lim ET, Würtz P, Havulinna AS, Palta P, Tukiainen T, Rehnström K, Esko T, Mägi R et al.(2014). Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population. PLoS Genetics vol. 10, (7)
10.1371/journal.pgen.1004494
Gaetano TJ, Danzy J, Mtshali MS, Theron N, Schmitt CA, Grobler JP, Freimer N, Turner TR(2014). Erratum: Mapping correlates of parasitism in wild South African vervet monkeys Chlorocebus aethiops (South African Journal of Wildlife Research (2014) 44:1 (56-70)). African Journal of Wildlife Research vol. 44, (2)
10.3957/056.044.0214
Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2014). Estimated urinary sodium excretion and risk of heart failure in men and women in the EPIC-Norfolk study. European Journal of Heart Failure vol. 16, (4) 394-402.
10.1002/ejhf.56
Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal-lari R, Desai K, Kar S, Hillman KM et al.(2014). Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications vol. 4,
10.1038/ncomms5999
Ma D, Jasinska AJ, Feyertag F, Wijewardana V, Kristoff J, He T, Raehtz K, Schmitt CA et al.(2014). Factors associated with siman immunodeficiency virus transmission in a natural african nonhuman primate host in the wild. Journal of Virology vol. 88, (10) 5687-5705.
10.1128/JVI.03606-13
Paschou P, Yu D, Gerber G, Evans P, Tsetsos F, Davis LK, Karagiannidis I, Chaponis J et al.(2014). Genetic association signal near NTN4 in Tourette syndrome. Annals of Neurology vol. 76, (2) 310-315.
10.1002/ana.24215
Moayyeri A, Hsu YH, Karasik D, Estrada K, Xiao SM, Nielson C, Srikanth P, Giroux S et al.(2014). Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Human Molecular Genetics vol. 23, (11) 3054-3068.
10.1093/hmg/ddt675
Ahmadi-Abhari S, Kaptoge S, Luben RN, Wareham NJ, Khaw KT(2014). Longitudinal association of C-reactive protein and lung function over 13 years. American Journal of Epidemiology vol. 179, (1) 48-56.
10.1093/aje/kwt208
Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2014). Low Bone Mineral Density Predicts Incident Heart Failure in Men and Women. The EPIC (European Prospective Investigation Into Cancer and Nutrition)-Norfolk Prospective Study. JACC: Heart Failure vol. 2, (4) 380-389.
10.1016/j.jchf.2014.03.010
Fears SC, Service SK, Kremeyer B, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G et al.(2014). Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees. JAMA Psychiatry vol. 71, (4) 375-387.
10.1001/jamapsychiatry.2013.4100
Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH, Teumer A, Winkler TW et al.(2014). Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genetics vol. 10, (7) 1-12.
10.1371/journal.pgen.1004508
Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S et al.(2014). Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. American Journal of Human Genetics vol. 95, (5) 535-552.
10.1016/j.ajhg.2014.10.004
Dobson RJB, Munroe PB, Caulfield MJ, Saqi MAS(2014). Protein interaction networks associated with cardiovascular disease and cancer: exploring the effect of bias on shared network properties. INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS vol. 9, (4) 339-357.
10.1504/IJDMB.2014.062150
Service SK, Teslovich TM, Fuchsberger C, Ramensky V, Yajnik P, Koboldt DC, Larson DE, Zhang Q et al.(2014). Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci. PLoS Genetics vol. 10, (1)
10.1371/journal.pgen.1004147
Leng Y, Wainwright NWJ, Cappuccio FP, Surtees PG, Luben R, Wareham N, Brayne C, Khaw KT(2014). Self-reported sleep patterns in a british population cohort. Sleep Medicine vol. 15, (3) 295-302.
10.1016/j.sleep.2013.10.015
Khaw KT, Luben R, Wareham N(2014). Serum 25-hydroxyvitamin D, mortality, and incident cardiovascular disease, respiratory disease, cancers, and fractures: A 13-y prospective population study. American Journal of Clinical Nutrition vol. 100, (5) 1361-1370.
10.3945/ajcn.114.086413
Patel PS, Cooper AJM, O'Connell TC, Kuhnle GGC, Kneale CK, Mulligan AM, Luben RN, Brage S et al.(2014). Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: The EPIC-Norfolk study. American Journal of Clinical Nutrition vol. 100, (2) 708-718.
10.3945/ajcn.113.068577
Wainwright NWJ, Levy S, Pico J, Luben RN, Surtees PG, Khaw KT(2014). Social adversity experience and blood pressure control following antihypertensive medication use in a community sample of older adults. International journal of behavioral medicine vol. 21, (3) 456-463.
10.1007/s12529-013-9319-9
Khawaja AP, Chan MPY, Broadway DC, Garway-Heath DF, Luben R, Yip JLY, Hayat S, Wareham NJ et al.(2014). Systemic medication and intraocular pressure in a british population: The EPIC-Norfolk Eye study. Ophthalmology vol. 121, (8) 1501-1507.
10.1016/j.ophtha.2014.02.009
Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N et al.(2014). The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior vol. 8, (2) 153-182.
10.1007/s11682-013-9269-5
Lahiri M, Luben RN, Morgan C, Bunn DK, Marshall T, Lunt M, Verstappen SMM, Symmons DPM et al.(2014). Using lifestyle factors to identify individuals at higher risk of inflammatory polyarthritis (results from the European Prospective Investigation of Cancer-Norfolk and the Norfolk Arthritis Register-the EPIC-2-NOAR Study). Annals of the Rheumatic Diseases vol. 73, (1) 219-226.
10.1136/annrheumdis-2012-202481
Kunutsor SK, Burgess S, Munroe PB, Khan H(2014). Vitamin D and high blood pressure: causal association or epiphenomenon?. EUROPEAN JOURNAL OF EPIDEMIOLOGY vol. 29, (1) 1-14.
10.1007/s10654-013-9874-z
Khawaja AP, Chan MPY, Broadway DC, Garway-Heath DF, Luben R, Yip JLY, Hayat S, Khaw KT et al.(2013). Corneal biomechanical properties and glaucoma-related quantitative traits in the EPIC-Norfolk eye study. Investigative Ophthalmology and Visual Science vol. 55, (1) 117-124.
10.1167/iovs.13-13290
Pooley KA, Bojesen SE, Weischer M, Nielsen SF, Thompson D, Amin Al Olama A, Michailidou K, Tyrer JP et al.(2013). A genome-wide association scan (GWAS) for mean telomere length within the COGS project: Identified loci show little association with hormone-related cancer risk. Human Molecular Genetics vol. 22, (24) 5056-5064.
10.1093/hmg/ddt355
Van Scheltinga AFT, Bakker SC, Van Haren NEM, Derks EM, Buizer-Voskamp JE, Cahn W, Ripke S, Ophoff RA et al.(2013). Schizophrenia genetic variants are not associated with intelligence. Psychological Medicine vol. 43, (12) 2563-2570.
10.1017/S0033291713000196
Sahlqvist S, Goodman A, Simmons RK, Khaw KT, Cavill N, Foster C, Luben R, Wareham NJ et al.(2013). The association of cycling with all-cause, cardiovascular and cancer mortality: Findings from the Population-based EPIC-Norfolk cohort. BMJ Open vol. 3, (11)
10.1136/bmjopen-2013-003797
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S et al.(2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics vol. 45, (11) 1345-1353.
10.1038/ng.2795
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S et al.(2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet vol. 45, (11) 1345-1352.
10.1038/ng.2795
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J et al.(2013). Discovery and refinement of loci associated with lipid levels. Nat Genet vol. 45, (11) 1274-1283.
10.1038/ng.2797
Strange A, Bellenguez C, Sim X, Luben R, Hysi PG, Ramdas WD, van Koolwijk LME, Freeman C et al.(2013). Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. Human Molecular Genetics vol. 22, (22) 4653-4660.
10.1093/hmg/ddt293
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23566
Jasinska AJ, Schmitt CA, Service SK, Cantor RM, Dewar K, Jentsch JD, Kaplan JR, Turner TR et al.(2013). Systems biology of the vervet monkey. ILAR Journal vol. 54, (2) 122-143.
10.1093/ilar/ilt049
Khawaja AP, Chan MPY, Broadway DC, Garway-Heath DF, Luben R, Yip JLY, Hayat S, Khaw KT et al.(2013). Laser scanning tomography in the EPIC-Norfolk eye study: Principal components and associations. Investigative Ophthalmology and Visual Science vol. 54, (10) 6638-6645.
10.1167/iovs.13-12490
Pfister R, Michels G, Wilfred J, Luben R, Wareham NJ, Khaw KT(2013). Does ICD-10 hospital discharge code I50 identify people with heart failure? A validation study within the EPIC-Norfolk study. International Journal of Cardiology vol. 168, (4) 4413-4414.
10.1016/j.ijcard.2013.05.031
Banim PJR, Luben R, McTaggart A, Welch A, Wareham N, Khaw KT, Hart AR(2013). Dietary antioxidants and the aetiology of pancreatic cancer: A cohort study using data from food diaries and biomarkers. Gut vol. 62, (10) 1489-1496.
10.1136/gutjnl-2011-301908
Yadav S, Cotlarciuc I, Munroe PB, Khan MS, Nalls MA, Bevan S, Cheng Y-C, Chen W-M et al.(2013). Genome-wide analysis of blood pressure variability and ischemic stroke. Stroke vol. 44, (10) 2703-2709.
10.1161/STROKEAHA.113.002186
Keevil VL, Hayat S, Dalzell N, Moore S, Bhaniani A, Luben R, Wareham NJ, Khaw KT(2013). The physical capability of community-based men and women from a British cohort: The European Prospective Investigation into Cancer (EPIC)-Norfolk study. BMC Geriatrics vol. 13, (1)
10.1186/1471-2318-13-93
Day AC, Khawaja AP, Peto T, Hayat S, Luben R, Broadway DC, Khaw KT, Foster PJ(2013). The small eye phenotype in the EPIC-Norfolk eye study: Prevalence and visual impairment in microphthalmos and nanophthalmos. BMJ Open vol. 3, (7)
10.1136/bmjopen-2013-003280
Ahmadi-Abhari S, Luben RN, Wareham NJ, Khaw KT(2013). C-reactive protein and fracture risk: European Prospective Investigation into Cancer Norfolk Study. Bone vol. 56, (1) 67-72.
10.1016/j.bone.2013.05.009
Stoll G, Pietiläinen OPH, Linder B, Suvisaari J, Brosi C, Hennah W, Leppä V, Torniainen M et al.(2013). Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders. Nature Neuroscience vol. 16, (9) 1228-1237.
10.1038/nn.3484
Verstappen SMM, Lunt M, Luben RN, Chipping J, Marshall T, Khaw KT, Wareham N, Dixon WG et al.(2013). Demographic and disease-related predictors of abnormal lung function in patients with established inflammatory polyarthritis and a comparison with the general population. Annals of the Rheumatic Diseases vol. 72, (9) 1517-1523.
10.1136/annrheumdis-2012-201698
Ahmadi-Abhari S, Luben RN, Wareham NJ, Khaw KT(2013). Distribution and determinants of C-reactive protein in the older adult population: European prospective investigation into cancer-norfolk study. European Journal of Clinical Investigation vol. 43, (9) 899-911.
10.1111/eci.12116
Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A et al.(2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics vol. 45, (9) 984-994.
10.1038/ng.2711
O'Seaghdha CM, Wu H, Yang Q, Kapur K, Guessous I, Zuber AM, Koettgen A, Stoudmann C et al.(2013). Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations. PLOS GENETICS vol. 9, (9) Article ARTN e1003796,
10.1371/journal.pgen.1003796
Munroe PB, Johnson T(2013). Hypertension. Genomic and Personalized Medicine, vol. 2,
Hu YJ, Berndt SI, Gustafsson S, Ganna A, Hirschhorn J, North KE, Ingelsson E, Lin DY et al.(2013). Meta-analysis of gene-level associations for rare variants based on single-variant statistics. American Journal of Human Genetics vol. 93, (2) 236-248.
10.1016/j.ajhg.2013.06.011
Khawaja AP, Chan MPY, Garway-Heath DF, Broadway DC, Luben R, Sherwin JC, Hayat S, Khaw KT et al.(2013). Associations with retinal nerve fiber layer measures in the EPIC-Norfolk eye study. Investigative Ophthalmology and Visual Science vol. 54, (7) 5028-5034.
10.1167/iovs.13-11971
Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA et al.(2013). Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics vol. 22, (16) 3394-3395.
10.1093/hmg/ddt177
Patel PS, Sharp SJ, Jansen E, Luben RN, Khaw KT, Wareham NJ, Forouhi NG(2013). Erratum: Fatty acids measured in plasma and erythrocytemembrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: A pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort (American Journal of Clinical Nutrition (2010) 92 (1214-1222)). American Journal of Clinical Nutrition vol. 98, (1) 255-258.
10.3945/ajcn.113.065334
Ahmadi-Abhari S, Luben RN, Wareham NJ, Khaw KT(2013). Seventeen year risk of all-cause and cause-specific mortality associated with C-reactive protein, fibrinogen and leukocyte count in men and women: The EPIC-Norfolk study. European Journal of Epidemiology vol. 28, (7) 541-550.
10.1007/s10654-013-9819-6
Cramer JD, Gaetano T, Gray JP, Grobler P, Lorenz JG, Freimer NB, Schmitt CA, Turner TR(2013). Variation in scrotal color among widely distributed vervet monkey populations (chlorocebus aethiops pygerythrus and chlorocebus aethiops sabaeus). American Journal of Primatology vol. 75, (7) 752-762.
10.1002/ajp.22156
van der Linde RM, Mavaddat N, Luben R, Brayne C, Simmons RK, Khaw KT, Kinmonth AL(2013). Self-Rated Health and Cardiovascular Disease Incidence: Results from a Longitudinal Population-Based Cohort in Norfolk, UK. PLoS ONE vol. 8, (6)
10.1371/journal.pone.0065290
Pfister R, Luben RN, Khaw KT, Wareham NJ(2013). Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study. European Journal of Heart Failure vol. 15, (6) 624-627.
10.1093/eurjhf/hft007
Lentjes MAH, Welch AA, Luben RN, Khaw KT(2013). Differences in dietary supplement use and secular and seasonal trends assessed using three different instruments in the EPIC-norfolk population study. Journal of Dietary Supplements vol. 10, (2) 142-151.
10.3109/19390211.2013.790336
Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E et al.(2013). Genome-wide association study of Tourette's syndrome. Molecular Psychiatry vol. 18, (6) 721-728.
10.1038/mp.2012.69
Day AC, Luben R, Khawaja AP, Low S, Hayat S, Dalzell N, Wareham NJ, Khaw KT et al.(2013). Genotype-phenotype analysis of SNPs associated with primary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular biometry in the EPIC-Norfolk Eye Study. British Journal of Ophthalmology vol. 97, (6) 704-707.
10.1136/bjophthalmol-2012-302969
Den Hoed M, Eijgelsheim M, Esko T, Brundel BJJM, Peal DS, Evans DM, Nolte IM, Segrè AV et al.(2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics vol. 45, (6) 621-631.
10.1038/ng.2610
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T et al.(2013). Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLoS Genetics vol. 9, (6)
10.1371/journal.pgen.1003500
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19179
Gkrania-Klotsas E, Langenberg C, Sharp SJ, Luben R, Khaw KT, Wareham NJ(2013). Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based european prospective investigation of cancer-norfolk cohort. Clinical Infectious Diseases vol. 56, (10) 1421-1427.
10.1093/cid/cit083
Munroe PB, Barnes MR, Caulfield MJ(2013). Advances in blood pressure genomics. Circ Res vol. 112, (10) 1365-1379.
10.1161/CIRCRESAHA.112.300387
Berndt SI, Gustafsson S, Maegi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL et al.(2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. NATURE GENETICS vol. 45, (5) 501-U69.
10.1038/ng.2606
Khawaja AP, Chan MPY, Hayat S, Broadway DC, Luben R, Garway-Heath DF, Sherwin JC, Yip JLY et al.(2013). The EPIC-Norfolk eye study: Rationale, methods and a cross-sectional analysis of visual impairment in a population-based cohort. BMJ Open vol. 3, (3)
10.1136/bmjopen-2013-002684
Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA et al.(2013). Loci influencing blood pressure identified using a cardiovascular gene-centric array. HUMAN MOLECULAR GENETICS vol. 22, (8) 1663-1678.
10.1093/hmg/dds555
Huertas-Vazquez A, Nelson CP, Guo X, Reinier K, Uy-Evanado A, Teodorescu C, Ayala J, Jerger K et al.(2013). Novel Loci Associated with Increased Risk of Sudden Cardiac Death in the Context of Coronary Artery Disease. PLoS ONE vol. 8, (4)
10.1371/journal.pone.0059905
Chan SSM, Luben R, Olsen A, Tjonneland A, Kaaks R, Teucher B, Lindgren S, Grip O et al.(2013). Body mass index and the risk for crohn's disease and ulcerative colitis: Data from a european prospective cohort study (The IBD in EPIC Study). American Journal of Gastroenterology vol. 108, (4) 575-582.
10.1038/ajg.2012.453
Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J et al.(2013). Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nature Genetics vol. 45, (4) 353-361.
10.1038/ng.2563
Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA et al.(2013). Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics vol. 45, (4) 371-384.
10.1038/ng.2566
Nag A, Bochukova EG, Kremeyer B, Campbell DD, Muller H, Valencia-Duarte AV, Cardona J, Rivas IC et al.(2013). CNV Analysis in Tourette Syndrome Implicates Large Genomic Rearrangements in COL8A1 and NRXN1. PLoS ONE vol. 8, (3)
10.1371/journal.pone.0059061
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13520
Terwisscha Van Scheltinga AF, Bakker SC, Van Haren NEM, Derks EM, Buizer-Voskamp JE, Boos HBM, Cahn W, Hulshoff Pol HE et al.(2013). Genetic schizophrenia risk variants jointly modulate total brain and white matter volume. Biological Psychiatry vol. 73, (6) 525-531.
10.1016/j.biopsych.2012.08.017
Verweij N, Mahmud H, Leach IM, de Boer RA, Brouwers FP, Yu H, Asselbergs FW, Struck J et al.(2013). Genome-Wide Association Study on Plasma Levels of Midregional-Proadrenomedullin and C-Terminal-Pro-Endothelin-1. HYPERTENSION vol. 61, (3) 602-+.
10.1161/HYPERTENSIONAHA.111.203117
Golubic R, Ekelund U, Wijndaele K, Luben R, Khaw KT, Wareham NJ, Brage S(2013). Rate of weight gain predicts change in physical activity levels: A longitudinal analysis of the EPIC-Norfolk cohort. International Journal of Obesity vol. 37, (3) 404-409.
10.1038/ijo.2012.58
Leng Y, Wainwright NWJ, Hayat S, Stephan BCM, Matthews FE, Luben R, Surtees PG, Khaw KT et al.(2013). The association between social stress and global cognitive function in a population-based study: The European Prospective Investigation into Cancer (EPIC)-Norfolk study. Psychological Medicine vol. 43, (3) 655-666.
10.1017/S0033291712001316
Chen K, Budman CL, Diego Herrera L, Witkin JE, Weiss NT, Lowe TL, Freimer NB, Reus VI et al.(2013). Prevalence and clinical correlates of explosive outbursts in Tourette Syndrome. Psychiatry Research vol. 205, (3) 269-275.
10.1016/j.psychres.2012.09.029
Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z et al.(2013). Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts. PLoS Medicine vol. 10, (2)
10.1371/journal.pmed.1001383
Koettgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D et al.(2013). Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. NATURE GENETICS vol. 45, (2) 145-154.
10.1038/ng.2500
Thorgeirsson TE, Gudbjartsson DF, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G, Walters GB, Furberg H et al.(2013). A common biological basis of obesity and nicotine addiction. Translational Psychiatry vol. 3, 1-7.
10.1038/tp.2013.81
Alvarez-Madrazo S, MacKenzie SM, Davies E, Fraser R, Lee W-K, Brown M, Caulfield MJ, Dominiczak AF et al.(2013). Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension. HYPERTENSION vol. 61, (1) 232-+.
10.1161/HYPERTENSIONAHA.112.200741
Guo Y, Lanktree MB, Taylor KC, Hakonarson H, Lange LA, Keating BJ, Guo Y, Lanktree MB et al.(2013). Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. Human Molecular Genetics vol. 22, (1) 184-201.
10.1093/hmg/dds396
Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J et al.(2013). Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture. PLoS Genetics vol. 9, (10)
10.1371/journal.pgen.1003864
May AM, Barnes DR, Forouhi NG, Luben R, Khaw KT, Wareham NJ, Peeters PHM, Sharp SJ(2013). Prediction of measured weight from self-reported weight was not improved after stratification by body mass index. Obesity vol. 21, (1) E137-E142.
10.1002/oby.20141
Ma D, Jasinska A, Kristoff J, Grobler JP, Turner T, Jung Y, Schmitt C, Raehtz K et al.(2013). SIVagm Infection in Wild African Green Monkeys from South Africa: Epidemiology, Natural History, and Evolutionary Considerations. PLoS Pathogens vol. 9, (1)
10.1371/journal.ppat.1003011
Gkrania-Klotsas E, Langenberg C, Sharp SJ, Luben R, Khaw KT, Wareham NJ(2012). Higher immunoglobulin G antibody levels against cytomegalovirus are associated with incident ischemic heart disease in the population-based EPIC-norfolk cohort. Journal of Infectious Diseases vol. 206, (12) 1897-1903.
10.1093/infdis/jis620
Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E et al.(2012). High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genetics vol. 44, (12) 1336-1340.
10.1038/ng.2462
Gurdasani D, Sjouke B, Tsimikas S, Hovingh GK, Luben RN, Wainwright NWJ, Pomilla C, Wareham NJ et al.(2012). Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: The EPIC-norfolk prospective population study. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 32, (12) 3058-3065.
10.1161/ATVBAHA.112.255521
Miettunen J, Isohanni M, Paunio T, Freimer N, Taanila A, Ekelund J, Järvelin MR, Joukamaa M et al.(2012). Predicting depression with psychopathology and temperament traits: The Northern Finland 1966 birth cohort. Depression Research and Treatment vol. 2012,
10.1155/2012/160905
Cooper JD, Simmonds MJ, Walker NM, Burren O, Brand OJ, Guo H, Wallace C, Stevens H et al.(2012). Seven newly identified loci for autoimmune thyroid disease. Human Molecular Genetics vol. 21, (23) 5202-5208.
10.1093/hmg/dds357
Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra MV, Rojas W et al.(2012). Erratum: Reconstructing Native American population history (Nature (2012) 488 (370-374) DOI:10.1038/nature11258). Nature vol. 491, (7423)
10.1038/nature11667
Asselbergs FW, Guo Y, van Iperen EPA, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B et al.(2012). Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci. AMERICAN JOURNAL OF HUMAN GENETICS vol. 91, (5) 823-838.
10.1016/j.ajhg.2012.08.032
Gay LJ, Mitrou PN, Keen J, Bowman R, Naguib A, Cooke J, Kuhnle GG, Burns PA et al.(2012). Dietary, lifestyle and clinicopathological factors associated with APC mutations and promoter methylation in colorectal cancers from the EPIC-Norfolk study. Journal of Pathology vol. 228, (3) 405-415.
10.1002/path.4085
Addison S, Sebire NJ, Taylor AM, Abrams D, Peebless D, Mein C, Munroe PB, Thayyil S(2012). High quality genomic DNA extraction from postmortem fetal tissue. JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE vol. 25, (11) 2467-2469.
10.3109/14767058.2012.704442
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Philip Schumm L et al.(2012). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature vol. 491, (7422) 119-124.
10.1038/nature11582
Surendran P, Vangjeli C, McCarthy N, Thom S, Sever P, O'Brien E, Poulter N, Mayet J et al.(2012). Genome-wide association analysis identifies the MTHFR-CLCN6-NPPA-NPPB gene cluster as an important influence on BNP levels-implications for the use of BNP levels in the diagnosis and therapeutic monitoring of heart failure-an ASCOT sub study. JOURNAL OF HUMAN HYPERTENSION vol. 26, (10) 620-620.
Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2012). Resting heart rate and incident heart failure in apparently healthy men and women in the EPIC-Norfolk study. European Journal of Heart Failure vol. 14, (10) 1163-1170.
10.1093/eurjhf/hfs104
Knaze V, Zamora-Ros R, Luján-Barroso L, Romieu I, Scalbert A, Slimani N, Riboli E, Van Rossum CTM et al.(2012). Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. British Journal of Nutrition vol. 108, (6) 1095-1108.
10.1017/S0007114511006386
Levine AJ, Service S, Miller EN, Reynolds SM, Singer EJ, Shapshak P, Martin EM, Sacktor N et al.(2012). Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 159 B, (6) 669-683.
10.1002/ajmg.b.32071
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, MäGi R, Strawbridge RJ et al.(2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics vol. 44, (9) 991-1005.
10.1038/ng.2385
Jamshidi Y, Nolte IM, Dalageorgou C, Zheng D, Johnson T, Bastiaenen R, Ruddy S, Talbott D et al.(2012). Common Variation in the NOS1AP Gene Is Associated With Drug-Induced QT Prolongation and Ventricular Arrhythmia. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY vol. 60, (9) 841-850.
10.1016/j.jacc.2012.03.031
Gencer B, Collet TH, Virgini V, Bauer DC, Gussekloo J, Cappola AR, Nanchen D, Den Elzen WPJ et al.(2012). Subclinical thyroid dysfunction and the risk of heart failure events an individual participant data analysis from 6 prospective cohorts. Circulation vol. 126, (9) 1040-1049.
10.1161/CIRCULATIONAHA.112.096024
Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra MV, Rojas W et al.(2012). Reconstructing Native American population history. Nature vol. 488, (7411) 370-374.
10.1038/nature11258
Jasinska AJ, Lin MK, Service S, Choi OW, DeYoung J, Grujic O, Kong SY, Jung Y et al.(2012). A non-human primate system for large-scale genetic studies of complex traits. Human Molecular Genetics vol. 21, (15) 3307-3316.
10.1093/hmg/dds160
Forouhi NG, Ye Z, Rickard AP, Khaw KT, Luben R, Langenberg C, Wareham NJ(2012). Circulating 25-hydroxyvitamin D concentration and the risk of type 2 diabetes: Results from the European Prospective Investigation into Cancer (EPIC)-Norfolk cohort and updated meta-analysis of Prospective studies. Diabetologia vol. 55, (8) 2173-2182.
10.1007/s00125-012-2544-y
Friese RS, Ye C, Nievergelt CM, Schork AJ, Mahapatra NR, Rao F, Napolitan PS, Waalen J et al.(2012). Integrated Computational and Experimental Analysis of the Neuroendocrine Transcriptome in Genetic Hypertension Identifies Novel Control Points for the Cardiometabolic Syndrome. CIRCULATION-CARDIOVASCULAR GENETICS vol. 5, (4) 430-440.
10.1161/CIRCGENETICS.111.962415
Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S et al.(2012). Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nature Genetics vol. 44, (8) 904-909.
10.1038/ng.2352
Voight BF, Kang HM, Ding J, Palmer CD, Sidore C, Chines PS, Burtt NP, Fuchsberger C et al.(2012). The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits. PLOS GENETICS vol. 8, (8) Article ARTN e1002793,
10.1371/journal.pgen.1002793
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5349
Pye SR, Marshall T, Gaffney K, Luben R, Khaw KT, Silman AJ, Symmons DPM, Oneill TW(2012). Influence of inflammatory polyarthritis on quantitative heel ultrasound measurements. BMC Musculoskeletal Disorders vol. 13,
10.1186/1471-2474-13-133
Congdon E, Service S, Wessman J, Seppänen JK, Schönauer S, Miettunen J, Turunen H, Koiranen M et al.(2012). Early environment and neurobehavioral development predict adult temperament clusters. PLoS ONE vol. 7, (7)
10.1371/journal.pone.0038065
Wessman J, Schönauer S, Miettunen J, Turunen H, Parviainen P, Seppänen JK, Congdon E, Service S et al.(2012). Temperament clusters in a normal population: Implications for health and disease. PLoS ONE vol. 7, (7)
10.1371/journal.pone.0033088
Vachon CM, Scott CG, Fasching PA, Hall P, Tamimi RM, Li J, Stone J, Apicella C et al.(2012). Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk. Cancer Epidemiology Biomarkers and Prevention vol. 21, (7) 1156-1166.
10.1158/1055-9965.EPI-12-0066
McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, Corre T, Davies G et al.(2012). Evidence of inbreeding depression on human height. PLoS Genetics vol. 8, (7)
10.1371/journal.pgen.1002655
Stevens KN, Lindstrom S, Scott CG, Thompson D, Sellers TA, Wang X, Wang A, Atkinson E et al.(2012). Identification of a novel percent mammographic density locus at 12q24. Human Molecular Genetics vol. 21, (14) 3299-3305.
10.1093/hmg/dds158
Khaw KT, Friesen MD, Riboli E, Luben R, Wareham N(2012). Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: The EPIC-Norfolk prospective study. PLoS Medicine vol. 9, (7)
10.1371/journal.pmed.1001255
Sherwin JC, Khawaja AP, Broadway D, Luben R, Hayat S, Dalzell N, Wareham NJ, Khaw KT et al.(2012). Uncorrected refractive error in older British adults: The EPIC-Norfolk eye study. British Journal of Ophthalmology vol. 96, (7) 991-996.
10.1136/bjophthalmol-2011-301430
Derks EM, Vorstman JAS, Ripke S, Kahn RS, Ophoff RA, O'Donovan MC, Craddock N, Holmans PA et al.(2012). Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: A polygenic risk score analysis. PLoS ONE vol. 7, (6)
10.1371/journal.pone.0037852
Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H et al.(2012). Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)). American Journal of Human Genetics vol. 90, (6) 1116-1117.
10.1016/j.ajhg.2012.05.017
Cooper AJ, Khaw KT, Sharp SJ, Wareham NJ, Lentjes MAH, Forouhi NG, Luben RN(2012). A prospective study of the association between quantity and variety of fruit and vegetable intake and incident type 2 diabetes. Diabetes Care vol. 35, (6) 1293-1300.
10.2337/dc11-2388
Karayiorgou M, Flint J, Gogos JA, Malenka RC, Bargmann CI, Boyden ES, Bullmore ET, Chan AW et al.(2012). The best of times, the worst of times for psychiatric disease. Nature Neuroscience vol. 15, (6) 811-812.
10.1038/nn.3115
Collet TH, Gussekloo J, Bauer DC, Den Elzen WPJ, Cappola AR, Balmer P, Iervasi G, Åsvold BO et al.(2012). Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Archives of Internal Medicine vol. 172, (10) 799-809.
10.1001/archinternmed.2012.402
Service SK, Verweij KJH, Lahti J, Congdon E, Ekelund J, Hintsanen M, Räikkönen K, Lehtimäki T et al.(2012). A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. Translational Psychiatry vol. 2,
10.1038/tp.2012.37
Moayyeri A, Luben RN, Wareham NJ, Khaw KT(2012). Body fat mass is a predictor of risk of osteoporotic fractures in women but not in men: A prospective population study. Journal of Internal Medicine vol. 271, (5) 472-480.
10.1111/j.1365-2796.2011.02443.x
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OME et al.(2012). Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics vol. 44, (5) 491-501.
10.1038/ng.2249
Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K et al.(2012). Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics vol. 44, (5) 552-561.
10.1038/ng.2250
Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A et al.(2012). Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)). American Journal of Human Genetics vol. 90, (4)
10.1016/j.ajhg.2012.03.001
Freitas RN, Luben R, Wareham NJ, Khaw KT(2012). Relationship between plasma fibrinogen and fiber intake in the EPIC-Norfolk cohort. European Journal of Clinical Nutrition vol. 66, (4) 443-451.
10.1038/ejcn.2011.194
Keller MC, Simonson MA, Ripke S, Neale BM, Gejman PV, Howrigan DP, Lee SH, Lencz T et al.(2012). Runs of homozygosity implicate autozygosity as a schizophrenia risk factor. PLoS Genetics vol. 8, (4)
10.1371/journal.pgen.1002656
Gkrania-Klotsas E, Langenberg C, Tauriainen S, Sharp SJ, Luben R, Forouhi NG, Khaw KT, Hyöty H et al.(2012). The association between prior infection with five serotypes of Coxsackievirus B and incident type 2 diabetes mellitus in the EPIC-Norfolk study. Diabetologia vol. 55, (4) 967-970.
10.1007/s00125-011-2443-7
Dastani Z, Hivert MF, Timpson N, Perry JRB, Yuan X, Scott RA, Henneman P, Heid IM et al.(2012). Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals. PLoS Genetics vol. 8, (3)
10.1371/journal.pgen.1002607
Melzer D, Osborne NJ, Henley WE, Cipelli R, Young A, Money C, McCormack P, Luben R et al.(2012). Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women. Circulation vol. 125, (12) 1482-1490.
10.1161/CIRCULATIONAHA.111.069153
Varghese JS, Thompson DJ, Michailidou K, Lindström S, Turnbull C, Brown J, Leyland J, Warren RML et al.(2012). Mammographic breast density and breast cancer: Evidence of a shared genetic basis. Cancer Research vol. 72, (6) 1478-1484.
10.1158/0008-5472.CAN-11-3295
Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A et al.(2012). Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci. AMERICAN JOURNAL OF HUMAN GENETICS vol. 90, (3) 410-425.
10.1016/j.ajhg.2011.12.022
Surtees PG, Wainwright NWJ, Pooley KA, Luben RN, Khaw KT, Easton DF, Dunning AM(2012). Educational attainment and mean leukocyte telomere length in women in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study. Brain, Behavior, and Immunity vol. 26, (3) 414-418.
10.1016/j.bbi.2011.11.009
Ward HA, Keogh R, Lentjes M, Luben RN, Wareham NJ, Khaw KT(2012). Fibre intake in relation to serum total cholesterol levels and CHD risk: A comparison of dietary assessment methods. European Journal of Clinical Nutrition vol. 66, (3) 296-304.
10.1038/ejcn.2011.184
Kettunen J, Tukiainen T, Sarin AP, Ortega-Alonso A, Tikkanen E, Lyytikäinen LP, Kangas AJ, Soininen P et al.(2012). Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nature Genetics vol. 44, (3) 269-276.
10.1038/ng.1073
Brand JS, Van Der Schouw YT, Dowsett M, Folkerd E, Luben RN, Wareham NJ, Khaw KT(2012). Testosterone, SHBG and differential white blood cell count in middle-aged and older men. Maturitas vol. 71, (3) 274-278.
10.1016/j.maturitas.2011.12.007
Xue F, Li S, Luan J, Yuan Z, Luben RN, Khaw KT, Wareham NJ, Loos RJF et al.(2012). A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study. PLoS ONE vol. 7, (2)
10.1371/journal.pone.0031927
Angelakopoulou A, Shah T, Sofat R, Shah S, Berry DJ, Cooper J, Palmen J, Tzoulaki I et al.(2012). Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J vol. 33, (3) 393-407.
10.1093/eurheartj/ehr225
Pfister R, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2012). Differential white blood cell count and incident heart failure in men and women in the EPIC-Norfolk study. European Heart Journal vol. 33, (4) 523-530.
10.1093/eurheartj/ehr457
Salvi E, Kutalik Z, Glorioso N, Benaglio P, Frau F, Kuznetsova T, Arima H, Hoggart C et al.(2012). Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase. Hypertension vol. 59, (2) 248-255.
10.1161/HYPERTENSIONAHA.111.181990
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ et al.(2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics
10.1038/ng.2385
Park JY, Mitrou PN, Keogh RH, Luben RN, Wareham NJ, Khaw KT(2012). Self-reported and measured anthropometric data and risk of colorectal cancer in the EPIC-Norfolk study. International Journal of Obesity vol. 36, (1) 107-118.
10.1038/ijo.2011.61
Fears SC, Scheibel K, Abaryan Z, Lee C, Service SK, Jorgensen MJ, Fairbanks LA, Cantor RM et al.(2011). Anatomic brain asymmetry in vervet monkeys. PLoS ONE vol. 6, (12)
10.1371/journal.pone.0028243
Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I et al.(2011). Blood pressure loci identified with a gene-centric array. Am J Hum Genet vol. 89, (6) 688-700.
10.1016/j.ajhg.2011.10.013
Shah S, Nelson CP, Gaunt TR, van der Harst P, Barnes T, Braund PS, Lawlor DA, Casas J-P et al.(2011). Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circ Cardiovasc Genet vol. 4, (6) 626-635.
10.1161/CIRCGENETICS.111.960203
Bown MJ, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Gretarsdottir S, Badger SA et al.(2011). Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. American Journal of Human Genetics vol. 89, (5) 619-627.
10.1016/j.ajhg.2011.10.002
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC et al.(2011). Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (Nature Genetics (2010) 42 (949-960)). Nature Genetics vol. 43, (11)
10.1038/ng1111-1164a
Chambers JC, Zhang WH, Sehmi J, Li XZ, Wass MN, Van der Harst P, Holm H, Sanna S et al.(2011). Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. NAT GENET vol. 43, (11) 1131-U129.
10.1038/ng.970
Surtees PG, Wainwright NWJ, Pooley KA, Luben RN, Khaw KT, Easton DF, Dunning AM(2011). Life stress, emotional health, and mean telomere length in the European prospective investigation into cancer (EPIC)-Norfolk Population Study. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 66 A, (11) 1152-1162.
10.1093/gerona/glr112
Kuhnle GGC, Ward HA, Vogiatzoglou A, Luben RN, Mulligan A, Wareham NJ, Forouhi NG, Khaw KT(2011). Association between dietary phyto-oestrogens and bone density in men and postmenopausal women. British Journal of Nutrition vol. 106, (7) 1063-1069.
10.1017/S0007114511001309
Surakka I, Isaacs A, Karssen LC, Laurila PPP, Middelberg RPS, Tikkanen E, Ried JS, Lamina C et al.(2011). A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genetics vol. 7, (10)
10.1371/journal.pgen.1002333
Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Munroe PB, Psaty BM, Caulfield MJ et al.(2011). A large genome-wide association study of pulse pressure and mean arterial pressure reveals seven novel blood pressure LOCI. J HUM HYPERTENS vol. 25, (10) 647-647.
Brand JS, Chan MF, Dowsett M, Folkerd E, Wareham NJ, Luben RN, Van Der Schouw YT, Khaw KT(2011). Cigarette smoking and endogenous sex hormones in postmenopausal women. Journal of Clinical Endocrinology and Metabolism vol. 96, (10) 3184-3192.
10.1210/jc.2011-1165
Key TJ, Appleby PN, Cairns BJ, Luben R, Dahm CC, Akbaraly T, Brunner EJ, Burley V et al.(2011). Dietary fat and breast cancer: Comparison of results from food diaries and food-frequency questionnaires in the UK Dietary Cohort Consortium. American Journal of Clinical Nutrition vol. 94, (4) 1043-1052.
10.3945/ajcn.111.015735
Dahm CC, Keogh RH, Lentjes MAH, Spencer EA, Key TJ, Greenwood DC, Cade JE, Burley VJ et al.(2011). Erratum to " Intake of dietary fats and colorectal cancer risk: Prospective findings from the UK Dietary Cohort Consortium" [Cancer Epidemiol. 34 (2010) 562-567]. Cancer Epidemiology vol. 35, (5)
10.1016/j.canep.2011.07.005
Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME et al.(2011). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes vol. 60, (10) 2624-2634.
10.2337/db11-0415
Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM et al.(2011). Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. NAT GENET vol. 43, (10) 1005-U122.
10.1038/ng.922
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19185
Foster PJ, Broadway DC, Garway-Heath DF, Yip JLY, Luben R, Hayat S, Dalzell N, Wareham NJ et al.(2011). Intraocular pressure and corneal biomechanics in an adult British population: The EPIC-Norfolk eye study. Investigative Ophthalmology and Visual Science vol. 52, (11) 8179-8185.
10.1167/iovs.11-7853
Gay LJ, Arends MJ, Mitrou PN, Bowman R, Ibrahim AE, Happerfield L, Luben R, McTaggart A et al.(2011). MLH1 promoter methylation, diet, and lifestyle factors in mismatch repair deficient colorectal cancer patients from EPIC-Norfolk. Nutrition and Cancer vol. 63, (7) 1000-1010.
10.1080/01635581.2011.596987
Pfister R, Barnes D, Luben R, Forouhi NG, Bochud M, Khaw KT, Wareham NJ, Langenberg C(2011). No evidence for a causal link between uric acid and type 2 diabetes: A Mendelian randomisation approach. Diabetologia vol. 54, (10) 2561-2569.
10.1007/s00125-011-2235-0
McCarthy N, Vangjeli C, Surendran P, Treumann A, Rooney C, Ho E, Sever P, Thom S et al.(2011). PPARGC1 beta is a genetic determinant of the cardiovascular risk factor, Thromboxane A2-an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) sub-study. J HUM HYPERTENS vol. 25, (10) 625-625.
Yip JLY, Broadway DC, Luben R, Garway-Heath DF, Hayat S, Dalzell N, Lee PS, Bhaniani A et al.(2011). Physical activity and Ocular perfusion pressure: The EPIC-Norfolk eye study. Investigative Ophthalmology and Visual Science vol. 52, (11) 8186-8192.
10.1167/iovs.11-8267
Ehret G, Munroe PB, Rice K, Bochud M, Johnson A, Chasman D, Vernon-Smith A, Psaty B et al.(2011). Sixteen novel loci influence blood pressure and cardiovascular risk. J HUM HYPERTENS vol. 25, (10) 635-636.
International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV et al.(2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature vol. 478, (7367) 103-109.
10.1038/nature10405
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13815
Chan SSM, Luben R, Bergmann MM, Boeing H, Olsen A, Tjonneland A, Overvad K, Kaaks R et al.(2011). Aspirin in the aetiology of Crohn's disease and ulcerative colitis: A European prospective cohort study. Alimentary Pharmacology and Therapeutics vol. 34, (6) 649-655.
10.1111/j.1365-2036.2011.04784.x
Myint PK, Luben RN, Wareham NJ, Khaw KT(2011). Association between plasma vitamin C concentrations and blood pressure in the European prospective investigation into cancer-norfolk population-based study. Hypertension vol. 58, (3) 372-379.
10.1161/HYPERTENSIONAHA.111.171108
Spencer EA, Key TJ, Appleby PN, Dahm CC, Keogh RH, Fentiman IS, Akbaraly T, Brunner EJ et al.(2011). Erratum: Meat, poultry and fish and risk of colorectal cancer: Pooled analysis of data from the UK dietary cohort consortium (Cancer Causes Control (2010) 21 (1417-1425)) DOI 10.1007/s10552-010-9569-7). Cancer Causes and Control vol. 22, (9)
10.1007/s10552-011-9815-7
Matthews FE, Stephan BCM, Khaw KT, Hayat S, Luben R, Bhaniani A, Moore S, Brayne C(2011). Full-scale scores of the Mini Mental State Examination can be generated from an abbreviated version. Journal of Clinical Epidemiology vol. 64, (9) 1005-1013.
10.1016/j.jclinepi.2010.11.014
Pfister R, Barnes D, Luben RN, Khaw KT, Wareham NJ, Langenberg C(2011). Individual and cumulative effect of type 2 diabetes genetic susceptibility variants on risk of coronary heart disease. Diabetologia vol. 54, (9) 2283-2287.
10.1007/s00125-011-2206-5
Myint PK, Smith RD, Luben RN, Surtees PG, Wainwright NWJ, Wareham NJ, Khaw KT(2011). Lifestyle behaviours and quality-adjusted life years in middle and older age. Age and Ageing vol. 40, (5) 589-595.
10.1093/ageing/afr058
Wegmann D, Kessner DE, Veeramah KR, Mathias RA, Nicolae DL, Yanek LR, Sun YV, Torgerson DG et al.(2011). Recombination rates in admixed individuals identified by ancestry-based inference. Nature Genetics vol. 43, (9) 847-853.
10.1038/ng.894
Ricketts SL, Rensing KL, Holly JM, Chen L, Young EH, Luben R, Ashford S, Song K et al.(2011). Prospective study of insulin-like growth factor-I, insulinlike growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. International Journal of Molecular Epidemiology and Genetics vol. 2, (3) 261-285.
Kilpeläinen TO, Zillikens MC, Stan¿ákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS et al.(2011). Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genetics vol. 43, (8) 753-760.
10.1038/ng.866
Pfister R, Sharp SJ, Luben R, Khaw KT, Wareham NJ(2011). No evidence of an increased mortality risk associated with low levels of glycated haemoglobin in a non-diabetic UK population. Diabetologia vol. 54, (8) 2025-2032.
10.1007/s00125-011-2162-0
Pfister R, Sharp SJ, Luben R, Wareham NJ, Khaw KT(2011). Plasma vitamin C predicts incident heart failure in men and women in European Prospective Investigation into Cancer and Nutrition-Norfolk prospective study. American Heart Journal vol. 162, (2) 246-253.
10.1016/j.ahj.2011.05.007
Loh YH, Mitrou PN, Wood A, Luben RN, McTaggart A, Khaw KT, Rodwell SA(2011). SMAD7 and MGMT genotype variants and cancer incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study. Cancer Epidemiology vol. 35, (4) 369-374.
10.1016/j.canep.2010.09.011
Banim PJR, Luben RN, Bulluck H, Sharp SJ, Wareham NJ, Khaw KT, Hart AR(2011). The aetiology of symptomatic gallstones quantification of the effects of obesity, alcohol and serum lipids on risk. Epidemiological and biomarker data from a UK prospective cohort study (EPIC-Norfolk). European Journal of Gastroenterology and Hepatology vol. 23, (8) 733-740.
10.1097/MEG.0b013e3283477cc9
Desrivières S, Lourdusamy A, Müller C, Ducci F, Wong CP, Kaakinen M, Pouta A, Hartikainen AL et al.(2011). Glucocorticoid receptor (NR3C1) gene polymorphisms and onset of alcohol abuse in adolescents. Addiction Biology vol. 16, (3) 510-513.
10.1111/j.1369-1600.2010.00239.x
Putku M, Kepp K, Org E, Sõber S, Comas D, Viigimaa M, Veldre G, Juhanson P et al.(2011). Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans. Hum Mutat vol. 32, (7) 806-814.
10.1002/humu.21508
Nyman E, Miettunen J, Freimer N, Joukamaa M, Mäki P, Ekelund J, Peltonen L, Järvelin MR et al.(2011). Impact of temperament on depression and anxiety symptoms and depressive disorder in a population-based birth cohort. Journal of Affective Disorders vol. 131, (1-3) 393-397.
10.1016/j.jad.2010.12.008
Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA et al.(2011). Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (Proceedings of the National Academy Sciences of the United States of America (2011) 108, 17, (7119-7124)). Proceedings of the National Academy of Sciences of the United States of America vol. 108, (22)
10.1073/pnas.1106917108
Wijndaele K, Brage S, Besson H, Khaw KT, Sharp SJ, Luben R, Bhaniani A, Wareham NJ et al.(2011). Television viewing and incident cardiovascular disease: Prospective associations and mediation analysis in the EPIC norfolk study. PLoS ONE vol. 6, (5)
10.1371/journal.pone.0020058
Johnson AD, Newton-Cheh C, Chasman DI, Ehret GB, Johnson T, Rose L, Rice K, Verwoert GC et al.(2011). Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals. Hypertension vol. 57, (5) 903-910.
10.1161/HYPERTENSIONAHA.110.158667
Brand JS, Wareham NJ, Dowsett M, Folkerd E, Van Der Schouw YT, Luben RN, Khaw KT(2011). Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men. Clinical Endocrinology vol. 74, (5) 572-578.
10.1111/j.1365-2265.2010.03951.x
Loh YH, Jakszyn P, Luben RN, Mulligan AA, Mitrou PN, Khaw KT(2011). N-nitroso compounds and cancer incidence: The European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study. American Journal of Clinical Nutrition vol. 93, (5) 1053-1061.
10.3945/ajcn.111.012377
Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA et al.(2011). Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America vol. 108, (17) 7119-7124.
10.1073/pnas.1017288108
Naguib A, Cooke JC, Happerfield L, Kerr L, Gay LJ, Luben RN, Ball RY, Mitrou PN et al.(2011). Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: Associations with clinicopathological and dietary factors. BMC Cancer vol. 11,
10.1186/1471-2407-11-123
Li S, Zhao JH, Luan J, Langenberg C, Luben RN, Khaw KT, Wareham NJ, Loos RJF(2011). Genetic predisposition to obesity leads to increased risk of type 2 diabetes. Diabetologia vol. 54, (4) 776-782.
10.1007/s00125-011-2044-5
Miettunen J, Veijola J, Isohanni M, Paunio T, Freimer N, Jääskeläinen E, Taanila A, Ekelund J et al.(2011). Identifying schizophrenia and other psychoses with psychological scales in the generasl population. Journal of Nervous and Mental Disease vol. 199, (4) 230-238.
10.1097/NMD.0b013e3182125d2c
Chamnan P, Simmons RK, Forouhi NG, Luben RN, Khaw KT, Wareham NJ, Griffin SJ(2011). Incidence of type 2 diabetes using proposed HbA<inf>1c</inf> diagnostic criteria in the european prospective investigation of cancer-norfolk cohort: Implications for preventive strategies. Diabetes Care vol. 34, (4) 950-956.
10.2337/dc09-2326
Ducci F, Kaakinen M, Pouta A, Hartikainen AL, Veijola J, Isohanni M, Charoen P, Coin L et al.(2011). TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood. Biological Psychiatry vol. 69, (7) 650-660.
10.1016/j.biopsych.2010.09.055
Ward H, Luben RN, Wareham NJ, Khaw KT(2011). CHD risk in relation to alcohol intake from categorical and open-ended dietary instruments. Public Health Nutrition vol. 14, (3) 402-409.
10.1017/S1368980010002041
Park JY, Mitrou PN, Keogh RH, Luben RN, Wareham NJ, Khaw KT(2011). Effects of body size and sociodemographic characteristics on differences between self-reported and measured anthropometric data in middle-aged men and women: The EPIC-Norfolk study. European Journal of Clinical Nutrition vol. 65, (3) 357-367.
10.1038/ejcn.2010.259
Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G et al.(2011). Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genetics vol. 7, (3)
10.1371/journal.pgen.1001324
Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H et al.(2011). Meta-analysis of genome-wide association studies in &gt;80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation vol. 123, (7) 731-738.
10.1161/CIRCULATIONAHA.110.948570
Woods RP, Fears SC, Jorgensen MJ, Fairbanks LA, Toga AW, Freimer NB(2011). A web-based brain atlas of the vervet monkey, Chlorocebus aethiops. NeuroImage vol. 54, (3) 1872-1880.
10.1016/j.neuroimage.2010.09.070
Dominiczak AF, Munroe PB(2011). Erratum: Genome-wide association studies will unlock the genetic basis of hypertension: Pro side of the argument (Hypertension (2010) 56 (1017-1020)). Hypertension vol. 57, (2)
10.1161/HYP.0b013e31820754a6
Kremeyer B, García J, Müller H, Burley MW, Herzberg I, Parra MV, Duque C, Vega J et al.(2011). Genome-wide linkage scan of bipolar disorder in a Colombian population isolate replicates loci on chromosomes 7p21-22, 1p31, 16p12 and 21q21-22 and identifies a novel locus on chromosome 12q. Human Heredity vol. 70, (4) 255-268.
10.1159/000320914
Wijndaele K, Brage S, Besson H, Khaw KT, Sharp SJ, Luben R, Wareham NJ, Ekelund U(2011). Television viewing time independently predicts all-cause and cardiovascular mortality: The EPIC Norfolk study. International Journal of Epidemiology vol. 40, (1) 150-159.
10.1093/ije/dyq105
Lanktree MB, Guo YR, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H et al.(2011). Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. AM J HUM GENET vol. 88, (1) 6-18.
10.1016/j.ajhg.2010.11.007
Steinberg S, Mors O, Børglum AD, Gustafsson O, Werge T, Mortensen PB, Andreassen OA, Sigurdsson E et al.(2011). Expanding the range of ZNF804A variants conferring risk of psychosis. Molecular Psychiatry vol. 16, (1) 59-66.
10.1038/mp.2009.149
Crane J, Fagerness J, Osiecki L, Gunnell B, Stewart SE, Pauls DL, Scharf JM, Cath D et al.(2011). Family-based genetic association study of DLGAP3 in Tourette Syndrome. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 156, (1) 108-114.
10.1002/ajmg.b.31134
Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J et al.(2011). Genome-wide association study identifies five new schizophrenia loci. Nature Genetics vol. 43, (10) 969-978.
10.1038/ng.940
Mumby HS, Elks CE, Li S, Sharp SJ, Khaw KT, Luben RN, Wareham NJ, Loos RJF et al.(2011). Mendelian randomisation study of childhood BMI and early menarche. Journal of Obesity vol. 2011,
10.1155/2011/180729
Pfister R, Sharp S, Luben R, Welsh P, Barroso I, Salomaa V, Meirhaeghe A, Khaw KT et al.(2011). Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: Evidence of causal association from population studies. PLoS Medicine vol. 8, (10)
10.1371/journal.pmed.1001112
Pietiläinen OPH, Rehnström K, Jakkula E, Service SK, Congdon E, Tilgmann C, Hartikainen AL, Taanila A et al.(2011). Phenotype mining in CNV carriers from a population cohort. Human Molecular Genetics vol. 20, (13) 2686-2695.
10.1093/hmg/ddr162
Sotoodehnia N, Isaacs A, de Bakker PIW, Dorr M, Newton-Cheh C, Nolte IM, van der Harst P, Muller M et al.(2010). Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. NAT GENET vol. 42, (12) 1068-U62.
10.1038/ng.716
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19344
Sivapalaratnam S, Boekholdt SM, Trip MD, Sandhu MS, Luben R, Kastelein JJP, Wareham NJ, Khaw KT(2010). Family history of premature coronary heart disease and risk prediction in the EPIC-Norfolk prospective population study. Heart vol. 96, (24) 1985-1989.
10.1136/hrt.2010.210740
Dominiczak AF, Munroe PB(2010). Genome-wide association studies will unlock the genetic basis of hypertension: Pro side of the argument. Hypertension vol. 56, (6) 1017-1020.
10.1161/HYPERTENSIONAHA.110.156208
Gkrania-Klotsas E, Ye Z, Cooper AJ, Sharp SJ, Luben R, Biggs ML, Chen LK, Gokulakrishnan K et al.(2010). Differential white blood cell count and type 2 diabetes: Systematic review and meta-analysis of cross-sectional and prospective studies. PLoS ONE vol. 5, (10)
10.1371/journal.pone.0013405
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM et al.(2010). Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet vol. 42, (11) 937-948.
10.1038/ng.686
Lovell MJ, Yasin M, Lee KL, Cheung KK, Shintani Y, Collino M, Sivarajah A, Leung K-Y et al.(2010). Bone marrow mononuclear cells reduce myocardial reperfusion injury by activating the PI3K/Akt survival pathway. Atherosclerosis vol. 213, (1) 67-76.
10.1016/j.atherosclerosis.2010.07.045
Tabara Y, Kohara K, Kita Y, Hirawa N, Katsuya T, Ohkubo T, Hiura Y, Tajima A et al.(2010). Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project. Hypertension vol. 56, (5) 973-980.
10.1161/HYPERTENSIONAHA.110.153429
Patel PS, Sharp SJ, Jansen E, Luben RN, Khaw KT, Wareham NJ, Forouhi NG(2010). Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: A pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort. American Journal of Clinical Nutrition vol. 92, (5) 1214-1222.
10.3945/ajcn.2010.29182
Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W et al.(2010). Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 30, (11) 2264-2276.
10.1161/ATVBAHA.109.201020
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC et al.(2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet vol. 42, (11) 949-960.
10.1038/ng.685
Padmanabhan S, Melander O, Johnson T, Di Blasio AM, Lee WK, Gentilini D, Hastie CE, Menni C et al.(2010). Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet vol. 6, (10)
10.1371/journal.pgen.1001177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19180
Congdon E, Poldrack RA, Freimer NB(2010). Neurocognitive phenotypes and genetic dissection of disorders of brain and behavior. Neuron vol. 68, (2) 218-230.
10.1016/j.neuron.2010.10.007
Allen HL, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU et al.(2010). Hundreds of variants clustered in genomic loci and biological pathways affect human height. NATURE vol. 467, (7317) 832-838.
10.1038/nature09410
Johnson T, Shaw-Hawkins S, Howard P, Lathrop M, Stanton A, Shields D, Poulter N, Sever P et al.(2010). A novel gene locus for blood pressure variability identified by genomewide association scanning in the Anglo-Scandinavian Cardiac Outcome Trial. J HUM HYPERTENS vol. 24, (10) 694-694.
Hastie CE, Padmanabhan S, Melander O, Johnson T, Di Blasio AM, Munroe PB, Caulfield M, Zanchetti A et al.(2010). Genome wide association study of blood pressure extremes identifies variant in uromodulin gene associated with hypertension. J HUM HYPERTENS vol. 24, (10) 687-687.
Dahm CC, Keogh RH, Lentjes MAH, Spencer EA, Key TJ, Greenwood DC, Cade JE, Burley VJ et al.(2010). Intake of dietary fats and colorectal cancer risk: Prospective findings from the UK Dietary Cohort Consortium. Cancer Epidemiology vol. 34, (5) 562-567.
10.1016/j.canep.2010.07.008
Munroe PB, Human CVD55 Blood Pressure Consort(2010). Meta-analyses of the HumanCVD55 beadchip discovers new blood pressure genes. J HUM HYPERTENS vol. 24, (10) 696-696.
Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, Bingham SA(2010). A single nucleotide polymorphism in the 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene (HMGCR) influences the serum triacylglycerol relationship with dietary fat and fibre in the European Prospective Investigation into Cancer and Nutrition in Norfolk (EPIC-Norfolk) study. British Journal of Nutrition vol. 104, (5) 765-772.
10.1017/S0007114510001145
Moayyeri A, Besson H, Luben RN, Wareham NJ, Khaw KT(2010). The association between physical activity in different domains of life and risk of osteoporotic fractures. Bone vol. 47, (3) 693-700.
10.1016/j.bone.2010.06.023
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S et al.(2010). Biological, clinical and population relevance of 95 loci for blood lipids. NATURE vol. 466, (7307) 707-713.
10.1038/nature09270
Park JY, Dahm CC, Keogh RH, Mitrou PN, Cairns BJ, Greenwood DC, Spencer EA, Fentiman IS et al.(2010). Alcohol intake and risk of colorectal cancer: Results from the UK Dietary Cohort Consortium. British Journal of Cancer vol. 103, (5) 747-756.
10.1038/sj.bjc.6605802
Li S, Zhao JH, Luan J, Ekelund U, Luben RN, Khaw KT, Wareham NJ, Loos RJF(2010). Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study. PLoS Medicine vol. 7, (8)
10.1371/journal.pmed.1000332
Miettunen J, Veijola J, Freimer N, Lichtermann D, Peltonen L, Paunio T, Isohanni M, Joukamaa M et al.(2010). Data on schizotypy and affective scales are gender and education dependent - Study in the Northern Finland 1966 Birth Cohort. Psychiatry Research vol. 178, (2) 408-413.
10.1016/j.psychres.2008.07.022
Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Emerick K, Antoniou A, Wanty C, Fischler B et al.(2010). Differences in presentation and progression between severe FIC1 and BSEP deficiencies. Journal of Hepatology vol. 53, (1) 170-178.
10.1016/j.jhep.2010.01.034
Foster PJ, Broadway DC, Hayat S, Luben R, Dalzell N, Bingham S, Wareham NJ, Khaw KT(2010). Refractive error, axial length and anterior chamber depth of the eye in British adults: The EPIC-Norfolk Eye Study. British Journal of Ophthalmology vol. 94, (7) 827-830.
10.1136/bjo.2009.163899
Udler MS, Ahmed S, Healey CS, Meyer K, Struewing J, Maranian M, Kwon EM, Zhang J et al.(2010). Fine scale mapping of the breast cancer 16q12 locus. Human Molecular Genetics vol. 19, (12) 2507-2515.
10.1093/hmg/ddq122
Padmanabhan S, Melander O, Johnson T, Di Blasio AM, Lee WK, Navis G, Bochud M, Munroe PB et al. (2010). GENOME WIDE ASSOCIATION STUDY OF BLOOD PRESSURE EXTREMES IDENTIFIES VARIANT IN UMOD ASSOCIATED WITH HYPERTENSION. JOURNAL OF HYPERTENSION. vol. 28, E237-E237.
Alvarez-Madrazo S, Padmanabhan S, Friel E, MacKenzie SM, Brown MJ, Caulfield MJ, Munroe PB, Farrall M et al. (2010). Validation of Association of Hypertension at the CYP11B1/B2 Locus in Caucasians. ENDOCRINE REVIEWS. vol. 31,
Widén E, Ripatti S, Cousminer DL, Surakka I, Lappalainen T, Järvelin MR, Eriksson JG, Raitakari O et al.(2010). Distinct Variants at LIN28B Influence Growth in Height from Birth to Adulthood. American Journal of Human Genetics vol. 86, (5) 773-782.
10.1016/j.ajhg.2010.03.010
Dahm CC, Keogh RH, Spencer EA, Greenwood DC, Key TJ, Fentiman IS, Shipley MJ, Brunner EJ et al.(2010). Dietary fiber and colorectal cancer risk: A nested case-control study using food diaries. Journal of the National Cancer Institute vol. 102, (9) 614-626.
10.1093/jnci/djq092
John S, Luben R, Shrestha SS, Welch A, Khaw KT, Hart AR(2010). Dietary n-3 polyunsaturated fatty acids and the aetiology of ulcerative colitis: A UK prospective cohort study. European Journal of Gastroenterology and Hepatology vol. 22, (5) 602-606.
10.1097/MEG.0b013e3283352d05
Chambers JC, Zhang WH, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN et al.(2010). Genetic loci influencing kidney function and chronic kidney disease. NAT GENET vol. 42, (5) 373-375.
10.1038/ng.566
Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, Berrettini W, Knouff CW et al.(2010). Meta-analysis and imputation refines the association of 15q25 with smoking quantity. NAT GENET vol. 42, (5) 436-U75.
10.1038/ng.572
Myint PK, Luben RN, Surtees PG, Wainwright NWJ, Wareham NJ, Khaw KT(2010). Physical functional health predicts the incidence of coronary heart disease in the European prospective investigation into Cancer-Norfolk prospective population-based study. International Journal of Epidemiology vol. 39, (4) 996-1003.
10.1093/ije/dyq061
Pooley KA, Sandhu MS, Tyrer J, Shah M, Driver KE, Luben RN, Bingham SA, Ponder BAJ et al.(2010). Telomere length in prospective and retrospective cancer case-control studies. Cancer Research vol. 70, (8) 3170-3176.
10.1158/0008-5472.CAN-09-4595
Loh YH, Mitrou PN, Bowman R, Wood A, Jeffery H, Luben RN, Lentjes MAH, Khaw KT et al.(2010). MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study. DNA Repair vol. 9, (4) 421-428.
10.1016/j.dnarep.2010.01.002
Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G et al.(2010). Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution. PLOS GENET vol. 6, (4) Article e1000508,
10.1371/journal.pgen.1000508
Craddock N, Hurles ME, Cardin N, Pearson RD, Plagnol V, Robson S, Vukcevic D, Barnes C et al.(2010). Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. NATURE vol. 464, (7289) 713-U86.
10.1038/nature08979
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14895
Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E(2010). Variance component model to account for sample structure in genome-wide association studies. Nature Genetics vol. 42, (4) 348-354.
10.1038/ng.548
Naguib A, Mitrou PN, Gay LJ, Cooke JC, Luben RN, Ball RY, McTaggart A, Arends MJ et al.(2010). Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study. BMC Cancer vol. 10,
10.1186/1471-2407-10-99
Boekholdt SM, Titan SM, Wiersinga WM, Chatterjee K, Basart DCG, Luben R, Wareham NJ, Khaw KT(2010). Initial thyroid status and cardiovascular risk factors: The EPIC-Norfolk prospective population study. Clinical Endocrinology vol. 72, (3) 404-410.
10.1111/j.1365-2265.2009.03640.x
Knight S, Coon H, Johnson M, Leppert MF, Camp NJ, McMahon WM, Cath D, Heutink P et al.(2010). Linkage analysis of Tourette syndrome in a large Utah pedigree. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 153, (2) 656-662.
10.1002/ajmg.b.31035
Ward HA, Kuhnle GGC, Mulligan AA, Lentjes MAH, Luben RN, Khaw KT(2010). Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database. American Journal of Clinical Nutrition vol. 91, (2) 440-448.
10.3945/ajcn.2009.28282
Pillas D, Hoggart CJ, Evans DM, O'Reilly PF, Sipilä K, Lähdesmäki R, Millwood IY, Kaakinen M et al.(2010). Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. PLoS Genetics vol. 6, (2)
10.1371/journal.pgen.1000856
Surtees PG, Wainwright NWJ, Luben RN, Khaw KT, Bingham SA(2010). No evidence that social stress is associated with breast cancer incidence. Breast Cancer Research and Treatment vol. 120, (1) 169-174.
10.1007/s10549-009-0454-6
Myint PK, Smith RD, Luben RN, Surtees PG, Wainwright NWJ, Wareham NJ, Bingham SA, Khaw KT(2010). The Short-Form Six-Dimension utility index predicted mortality in the European Prospective Investigation into Cancer-Norfolk prospective population-based study. Journal of Clinical Epidemiology vol. 63, (2) 192-198.
10.1016/j.jclinepi.2009.05.002
Li S, Zhao JH, Luan J, Luben RN, Rodwell SA, Khaw KT, Ong KK, Wareham NJ et al.(2010). Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies. American Journal of Clinical Nutrition vol. 91, (1) 184-190.
10.3945/ajcn.2009.28403
Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, Rodwell S(2010). HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study. European Journal of Preventive Cardiology vol. 17, (1) 89-93.
10.1097/HJR.0b013e328330be77
Park JY, Mitrou PN, Keen J, Dahm CC, Gay LJ, Luben RN, McTaggart A, Khaw KT et al.(2010). Lifestyle factors and p53 mutation patterns in colorectal cancer patients in the EPIC-Norfolk study. Mutagenesis vol. 25, (4) 351-358.
10.1093/mutage/geq012
Surtees PG, Wainwright NWJ, Luben R, Wareham NJ, Bingham SA, Khaw KT(2010). Mastery is associated with cardiovascular disease mortality in men and women at apparently low risk. Health Psychology vol. 29, (4) 412-420.
10.1037/a0019432
Spencer EA, Key TJ, Appleby PN, Dahm CC, Keogh RH, Fentiman IS, Akbaraly T, Brunner EJ et al.(2010). Meat, poultry and fish and risk of colorectal cancer: Pooled analysis of data from the UK dietary cohort consortium. Cancer Causes and Control vol. 21, (9) 1417-1425.
10.1007/s10552-010-9569-7
Banim PJR, Luben RN, Wareham NJ, Sharp SJ, Khaw KT, Hart AR(2010). Physical activity reduces the risk of symptomatic gallstones: A prospective cohort study. European Journal of Gastroenterology and Hepatology vol. 22, (8) 983-988.
10.1097/MEG.0b013e32833732c3
Hart A, Tjonneland A, Olsen A, Overvad K, Bergmann MM, Boeing H, Nagel G, Linseisen J et al.(2009). Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: A nested case-control study within a European prospective cohort study. Gut vol. 58, (12) 1606-1611.
10.1136/gut.2008.169078
Jasinska AJ, Freimer NB(2009). The complex genetic basis of simple behavior. Journal of Biology vol. 8, (8)
10.1186/jbiol172
Munroe PB, Johnson T, Caulfield MJ(2009). The genetic architecture of blood pressure variation. Current Cardiovascular Risk Reports vol. 3, (6) 418-425.
10.1007/s12170-009-0062-3
Sabb FW, Burggren AC, Higier RG, Fox J, He J, Parker DS, Poldrack RA, Chu W et al.(2009). Challenges in phenotype definition in the whole-genome era: Multivariate models of memory and intelligence. Neuroscience vol. 164, (1) 88-107.
10.1016/j.neuroscience.2009.05.013
Bilder RM, Sabb FW, Cannon TD, London ED, Jentsch JD, Parker DS, Poldrack RA, Evans C et al.(2009). Phenomics: The systematic study of phenotypes on a genome-wide scale. Neuroscience vol. 164, (1) 30-42.
10.1016/j.neuroscience.2009.01.027
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J et al.(2009). Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip. AM J HUM GENET vol. 85, (5) 628-642.
10.1016/j.ajhg.2009.10.014
Jasinska AJ, Service S, Choi OW, DeYoung J, Grujic O, Kong SY, Jorgensen MJ, Bailey J et al.(2009). Identification of brain transcriptional variation reproduced in peripheral blood: An approach for mapping brain expression traits. Human Molecular Genetics vol. 18, (22) 4415-4427.
10.1093/hmg/ddp397
Park JY, Mitrou PN, Dahm CC, Luben RN, Wareham NJ, Khaw KT, Rodwell SA(2009). Baseline alcohol consumption, type of alcoholic beverage and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition-Norfolk study. Cancer Epidemiology vol. 33, (5) 347-354.
10.1016/j.canep.2009.10.015
Chambers JC, Zhang W, Li Y, Sehmi J, Wass MN, Zabaneh D, Hoggart C, Bayele H et al.(2009). Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nature Genetics vol. 41, (11) 1170-1172.
10.1038/ng.462
Jasinska AJ, Service S, Jawaheer D, DeYoung J, Levinson M, Zhang Z, Kremeyer B, Muller H et al.(2009). A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigrees. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 150, (7) 998-1006.
10.1002/ajmg.b.30956
Patel PS, Sharp SJ, Luben RN, Khaw KT, Bingham SA, Wareham NJ, Forouhi NG(2009). Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes: The European Prospective Investigation of Cancer (EPIC)-Norfolk cohort study. Diabetes Care vol. 32, (10) 1857-1863.
10.2337/dc09-0116
Nyman ES, Loukola A, Varilo T, Ekelund J, Veijola J, Joukamaa M, Taanila A, Pouta A et al.(2009). Impact of the dopamine receptor gene family on temperament traits in a population-based birth cohort. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 150, (6) 854-865.
10.1002/ajmg.b.30908
Bilder RM, Sabb FW, Parker DS, Kalar D, Chu WW, Fox J, Freimer NB, Poldrack RA(2009). Cognitive ontologies for neuropsychiatric phenomics research. Cognitive Neuropsychiatry vol. 14, (4-5) 419-450.
10.1080/13546800902787180
Dobson RJB, Munroe PB, Caulfield MJ, Saqi MAS(2009). Global sequence properties for superfamily prediction: a machine learning approach. J Integr Bioinform vol. 6, (1)
10.2390/biecoll-jib-2009-109
Ward H, Mitrou PN, Bowman R, Luben R, Wareham NJ, Khaw KT, Bingham S(2009). APOE genotype, lipids, and coronary heart disease risk: A prospective population study. Archives of Internal Medicine vol. 169, (15) 1424-1429.
10.1001/archinternmed.2009.234
Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OPH et al.(2009). Common variants conferring risk of schizophrenia. Nature vol. 460, (7256) 744-747.
10.1038/nature08186
Moayyeri A, Kaptoge S, Dalzell N, Luben RN, Wareham NJ, Bingham S, Reeve J, Khaw KT(2009). The effect of including quantitative heel ultrasound in models for estimation of 10-year absolute risk of fracture. Bone vol. 45, (2) 180-184.
10.1016/j.bone.2009.05.001
Nolte IM, Wallace C, Newhouse SJ, Waggott D, Fu J, Soranzo N, Gwilliam R, Deloukas P et al.(2009). Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: Meta-analysis of three genome-wide association studies. PLoS ONE vol. 4, (7)
10.1371/journal.pone.0006138
Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, Bingham SA(2009). A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study. Journal of the American Society of Hypertension vol. 3, (4) 238-244.
10.1016/j.jash.2009.05.001
Elliott P, Chambers JC, Zhang W, Clarke R, Hopewell JC, Peden JF, Erdmann J, Braund P et al.(2009). Genetic loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA - Journal of the American Medical Association vol. 302, (1) 37-48.
10.1001/jama.2009.954
Moayyeri A, Kaptoge S, Dalzell N, Bingham S, Luben RN, Wareham NJ, Reeve J, Khaw KT(2009). Is QUS or DXA better for predicting the 10-year absolute risk of fracture?. Journal of Bone and Mineral Research vol. 24, (7) 1319-1325.
10.1359/jbmr.090212
Sõber S, Org E, Kepp K, Juhanson P, Eyheramendy S, Gieger C, Lichtner P, Klopp N et al.(2009). Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array. PLoS ONE vol. 4, (6)
10.1371/journal.pone.0006034
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12218
Bowman R, Joosen AMCP, Welch AA, Luben RN, Khaw KT, Wareham NJ, Bingham SA(2009). Factor VII, blood lipids and fat intake: Gene-nutrient interaction and risk of coronary heart disease with the factor VII R353Q polymorphism. European Journal of Clinical Nutrition vol. 63, (6) 771-777.
10.1038/ejcn.2008.28
Bingham S, Luben R, Welch A, Low YL, Khaw KT, Wareham N, Day N(2009). Author's response: Associations between dietary methods and biomarkers, and between fruits and vegetables and risk of ischaemic heart disease, in the EPIC Norfolk Cohort Study: Response to letter by McNeill et al. International Journal of Epidemiology vol. 38, (3)
10.1093/ije/dyn234
Org E, Eyheramendy S, Juhanson P, Gieger C, Lichtner P, Klopp N, Veldre G, Doring A et al.(2009). Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. HUM MOL GENET vol. 18, (12) 2288-2296.
10.1093/hmg/ddp135
Lee CC, Adler AI, Sandhu MS, Sharp SJ, Forouhi NG, Erqou S, Luben R, Bingham S et al.(2009). Association of C-reactive protein with type 2 diabetes: Prospective analysis and meta-analysis. Diabetologia vol. 52, (6) 1040-1047.
10.1007/s00125-009-1338-3
Ong KK, Elks CE, Li S, Zhao JH, Luan J, Andersen LB, Bingham SA, Brage S et al.(2009). Genetic variation in LIN28B is associated with the timing of puberty. Nature Genetics vol. 41, (6) 729-733.
10.1038/ng.382
Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G et al.(2009). Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution. PLOS GENET vol. 5, (6) Article e1000508,
10.1371/journal.pgen.1000508
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19181
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH et al.(2009). Genome-wide association study identifies eight loci associated with blood pressure. NAT GENET vol. 41, (6) 666-676.
10.1038/ng.361
Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E et al.(2009). Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations. PLOS GENET vol. 5, (6) Article e1000504,
10.1371/journal.pgen.1000504
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19172
Semb AG, Ueland T, Aukrust P, Wareham NJ, Luben R, Gullestad L, Kastelein JJP, Khaw KT et al.(2009). Osteoprotegerin and soluble receptor activator of nuclear factor-κB ligand and risk for coronary events: A nested case-control approach in the prospective EPIC-norfolk population study 1993-2003. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 29, (6) 975-980.
10.1161/ATVBAHA.109.184101
McFadden E, Luben R, Khaw KT(2009). Different measures of social class in women and mortality. European Journal of Epidemiology vol. 24, (5) 231-236.
10.1007/s10654-009-9332-0
Myint PK, Luben RN, Surtees PG, Wainwright NWJ, Bingham SA, Wareham NJ, Khaw KT(2009). Effect of Age and Sex on the Relationship Between Different Socioeconomic Indices and Self-Reported Functional Health in the EPIC-Norfolk Population-Based Study. Annals of Epidemiology vol. 19, (5) 289-297.
10.1016/j.annepidem.2009.02.003
Moayyeri A, Kaptoge S, Luben RN, Wareham NJ, Bingham S, Reeve J, Khaw KT(2009). Estimation of absolute fracture risk among middle-aged and older men and women: The EPIC-Norfolk population cohort study. European Journal of Epidemiology vol. 24, (5) 259-266.
10.1007/s10654-009-9337-8
Ahmed S, Thomas G, Ghoussaini M, Healey CS, Humphreys MK, Platte R, Morrison J, Maranian M et al.(2009). Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nature Genetics vol. 41, (5) 585-590.
10.1038/ng.354
Moayyeri A, Bingham SA, Luben RN, Wareham NJ, Khaw KT(2009). Respiratory function as a marker of bone health and fracture risk in an older population. Journal of Bone and Mineral Research vol. 24, (5) 956-963.
10.1359/jbmr.081231
Udler MS, Meyer KB, Pooley KA, Karlins E, Struewing JP, Zhang J, Doody DR, Macarthur S et al.(2009). FGFR2 variants and breast cancer risk: Fine-scale mapping using African American studies and analysis of chromatin conformation. Human Molecular Genetics vol. 18, (9) 1692-1703.
10.1093/hmg/ddp078
McFadden E, Luben R, Wareham N, Bingham S, Khaw KT(2009). How far can we explain the social class differential in respiratory function? A cross-sectional population study of 21,991 men and women from EPIC-Norfolk. European Journal of Epidemiology vol. 24, (4) 193-201.
10.1007/s10654-009-9326-y
Bearden CE, Jasinska AJ, Freimer NB(2009). Methodological issues in molecular genetic studies of mental disorders.
McFadden E, Luben R, Bingham S, Wareham N, Kinmonth AL, Khaw KT(2009). Self-rated health does not explain the socioeconomic differential in mortality: A prospective study in the EPIC-Norfolk cohort. Journal of Epidemiology and Community Health vol. 63, (4) 329-331.
10.1136/jech.2008.078139
McFadden E, Luben R, Wareham N, Bingham S, Khaw KT(2009). Social class, risk factors, and stroke incidence in men and women a prospective study in the european prospective investigation into cancer in norfolk cohort. Stroke vol. 40, (4) 1070-1077.
10.1161/STROKEAHA.108.533414
Myint PK, Luben RN, Wareham NJ, Bingham SA, Khaw KT(2009). Combined effect of health behaviours and risk of first ever stroke in 20,040 men and women over 11 years' follow-up in Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): prospective population study. BMJ (Clinical research ed.) vol. 338,
10.1136/bmj.b349
Munafò MR, Freimer NB, Ng W, Ophoff R, Veijola J, Miettunen J, Järvelin MR, Taanila A et al.(2009). 5-HTTLPR genotype and anxiety-related personality traits: A meta-analysis and new data. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 150, (2) 271-281.
10.1002/ajmg.b.30808
Fears SC, Melega WP, Service SK, Lee C, Chen K, Tu Z, Jorgensen MJ, Fairbanks LA et al.(2009). Identifying heritable brain phenotypes in an extended pedigree of vervet monkeys. Journal of Neuroscience vol. 29, (9) 2867-2875.
10.1523/JNEUROSCI.5153-08.2009
Sovio U, Bennett AJ, Millwood LY, Molitor J, O'Reilly PF, J.Timpson N, Kaakinen M, Laitinen J et al.(2009). Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern finland birth cohort 1966. PLoS Genetics vol. 5, (3)
10.1371/journal.pgen.1000409
Kerner B, Jasinska AJ, DeYoung J, Almonte M, Choi OW, Freimer NB(2009). Polymorphisms in the GRIA1 gene region in psychotic bipolar disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 150, (1) 24-32.
10.1002/ajmg.b.30780
McFadden E, Luben R, Bingham S, Wareham N, Kinmonth AL, Khaw KT(2009). Does the association between self-rated health and mortality vary by social class?. Social Science and Medicine vol. 68, (2) 275-280.
10.1016/j.socscimed.2008.10.012
Lakshman R, Forouhi NG, Sharp SJ, Luben R, Bingham SA, Khaw KT, Wareham NJ, Ong KK(2009). Early age at menarche associated with cardiovascular disease and mortality. Journal of Clinical Endocrinology and Metabolism vol. 94, (12) 4953-4960.
10.1210/jc.2009-1789
Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, Brodsky J, Jones CG, Zaitlen NA et al.(2009). Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nature Genetics vol. 41, (1) 35-46.
10.1038/ng.271
Park JY, Mitrou PN, Luben R, Khaw KT, Bingham SA(2009). Is bowel habit linked to colorectal cancer? - Results from the EPIC-Norfolk study. European Journal of Cancer vol. 45, (1) 139-145.
10.1016/j.ejca.2008.10.002
Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BWJH, Janssens ACJW et al.(2009). Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nature Genetics vol. 41, (1) 47-55.
10.1038/ng.269
Surtees PG, Wainwright NWJ, Bowman R, Luben RN, Wareham NJ, Khaw KT, Bingham SA(2009). No association between APOE and major depressive disorder in a community sample of 17,507 adults. Journal of Psychiatric Research vol. 43, (9) 843-847.
10.1016/j.jpsychires.2008.12.001
Newhouse S, Farrall M, Wallace C, Hoti M, Burke B, Howard P, Onipinla A, Lee K et al.(2009). Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion. PLoS One vol. 4, (4)
10.1371/journal.pone.0005003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12217
Mallat Z, Simon T, Benessiano J, Clément K, Taleb S, Wareham NJ, Luben R, Khaw KT et al.(2009). Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women. Journal of Clinical Endocrinology and Metabolism vol. 94, (1) 255-260.
10.1210/jc.2008-0253
Willer CJ, Speliotes EK, Loos RJF, Li SX, Lindgren CM, Heid IM, Berndt SI, Elliott AL et al.(2009). Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. NAT GENET vol. 41, (1) 25-34.
10.1038/ng.287
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJF, Manning AK et al.(2009). Variants in MTNR1B influence fasting glucose levels. Nature Genetics vol. 41, (1) 77-81.
10.1038/ng.290
Jakkula E, Rehnström K, Varilo T, Pietiläinen OPH, Paunio T, Pedersen NL, deFaire U, Järvelin MR et al.(2008). The Genome-wide Patterns of Variation Expose Significant Substructure in a Founder Population. American Journal of Human Genetics vol. 83, (6) 787-794.
10.1016/j.ajhg.2008.11.005
Thompson DJ, Healey CS, Baynes C, Kalmyrzaev B, Ahmed S, Dowsett M, Folkerd E, Luben RN et al.(2008). Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women. Cancer Epidemiology Biomarkers and Prevention vol. 17, (12) 3490-3498.
10.1158/1055-9965.EPI-08-0734
Cotton RGH, Auerbach AD, Axton M, Barash CI, Berkovic SF, Brookes AJ, Burn J, Cutting G et al.(2008). Genetics: The human variome project. Science vol. 322, (5903) 861-862.
10.1126/science.1167363
Lee CTC, Adler AI, Forouhi NG, Luben R, Welch A, Khaw KT, Bingham S, Wareham NJ(2008). Cross-sectional Association Between Fish Consumption and Albuminuria: The European Prospective Investigation of Cancer-Norfolk Study. American Journal of Kidney Diseases vol. 52, (5) 876-886.
10.1053/j.ajkd.2008.02.307
Wang J, Luben R, Khaw KT, Bingham S, Wareham NJ, Forouhi NG(2008). Dietary energy density predicts the risk of incident type 2 diabetes the european prospective investigation of cancer (EPIC)-norfolk study. Diabetes Care vol. 31, (11) 2120-2125.
10.2337/dc08-1085
Ishihara-Paul L, Wainwright NWJ, Khaw KT, Luben RN, Welch AA, Day NE, Brayne C, Surtees PG(2008). Prospective association between emotional health and clinical evidence of Parkinson's disease. European Journal of Neurology vol. 15, (11) 1148-1154.
10.1111/j.1468-1331.2008.02299.x
Besson H, Ekelund U, Brage S, Luben R, Bingham S, Khaw KT, Wareham NJ(2008). Relationship between subdomains of total physical activity and mortality. Medicine and Science in Sports and Exercise vol. 40, (11) 1909-1915.
10.1249/MSS.0b013e318180bcad
Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC et al.(2008). Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies. PLOS ONE vol. 3, (10) Article e3583,
10.1371/journal.pone.0003583
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19174
Bingham S, Luben R, Welch A, Low YL, Khaw KT, Wareham N, Day N(2008). Associations between dietary methods and biomarkers, and between fruits and vegetables and risk of ischaemic heart disease, in the EPIC Norfolk Cohort Study. International Journal of Epidemiology vol. 37, (5) 978-987.
10.1093/ije/dyn111
Caulfield MJ, Munroe PB, O'Neill D, Witkowska K, Charchar FJ, Doblado M, Evans S, Eyheramendy S et al.(2008). SLC2A9 is a high-capacity urate transporter in humans. PLoS Med vol. 5, (10)
10.1371/journal.pmed.0050197
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12221
Huq SM, Oldapo MNJ, Wang Y, Li J, Loo RL, Braund P, Tobin M, Barton P et al. (2008). High glucose and low lactate: a metabolic signature of hypertension in human serum?. HYPERTENSION. vol. 52, 758-759.
Ward H, Chapelais G, Kuhnle GGC, Luben R, Khaw KT, Bingham S(2008). Lack of prospective associations between plasma and urinary phytoestrogens and risk of prostate or colorectal cancer in the European Prospective into Cancer-Norfolk study. Cancer Epidemiology Biomarkers and Prevention vol. 17, (10) 2891-2894.
10.1158/1055-9965.EPI-08-0335
Surtees PG, Wainwright NWJ, Boekholdt SM, Luben RN, Wareham NJ, Khaw KT(2008). Major depression, c-reactive protein, and incident ischemic heart disease in healthy men and women. Psychosomatic Medicine vol. 70, (8) 850-855.
10.1097/PSY.0b013e318183acd5
Hoti M, Newhouse S, Clayton D, Samani NJ, Dominiczak AF, Brown MJ, Webster J, Lathrop M et al. (2008). WNK1 - functional analyses of variants associated with blood pressure and essential hypertension. J HUM HYPERTENS. vol. 22, 722-722.
Hoti M, Newhouse S, Clayton D, Samani NJ, Dominiczak AF, Brown MJ, Webster J, Lathrop M et al. (2008). WNK1-functional analyses of variants associated with blood pressure and essential hypertension. HYPERTENSION. vol. 52, 764-764.
Wainwright NWJ, Surtees PG, Welch AA, Luben RN, Khaw KT, Bingham SA(2008). Sense of coherence, lifestyle choices and mortality. Journal of Epidemiology and Community Health vol. 62, (9) 829-831.
10.1136/jech.2007.066464
McFadden E, Luben R, Bingham S, Wareham N, Kinmonth AL, Khaw KT(2008). Social inequalities in self-rated health by age: Cross-sectional study of 22 457 middle-aged men and women. BMC Public Health vol. 8,
10.1186/1471-2458-8-230
Norat T, Bowman R, Luben R, Welch A, Kay TK, Wareham N, Bingham S(2008). Blood pressure and interactions between the angiotensin polymorphism AGT M235T and sodium intake: A cross-sectional population study. American Journal of Clinical Nutrition vol. 88, (2) 392-397.
10.1093/ajcn/88.2.392
McFadden E, Luben R, Wareham N, Bingham S, Khaw KT(2008). Occupational social class, educational level, smoking and body mass index, and cause-specific mortality in men and women: A prospective study in the European Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort. European Journal of Epidemiology vol. 23, (8) 511-522.
10.1007/s10654-008-9267-x
Harding AH, Wareham NJ, Bingham SA, Khaw KT, Luben R, Welch A, Forouhi NG(2008). Plasma vitamin C level, fruit and vegetable consumption, and the risk of new-onset type 2 diabetes mellitus The European prospective investigation of Cancer-Norfolk prospective study. Archives of Internal Medicine vol. 168, (14) 1493-1499.
10.1001/archinte.168.14.1493
Delles C, Padmanabhan S, Lee WK, Miller WH, McBride MW, McClure JD, Brain NJ, Wallace C et al.(2008). Glutathione S-transferase variants and hypertension. J HYPERTENS vol. 26, (7) 1343-1352.
10.1097/HJH.0b013e3282fe1d67
McFadden E, Luben R, Wareham N, Bingham S, Khaw KT(2008). Occupational social class, risk factors and cardiovascular disease incidence in men and women: A prospective study in the European Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort. European Journal of Epidemiology vol. 23, (7) 449-458.
10.1007/s10654-008-9262-2
Service S, Molina J, DeYoung J, Jawaheer D, Aldana I, Vu T, Araya C, Araya X et al.(2008). Results of a SNP genome screen in a large Costa Rican pedigree segregating for severe bipolar disorder (American Journal of Medical Genetics, Part B: Neuropsychiatrics Genetics). American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 147, (4)
10.1002/ajmg.b.30438
Khaw KT, Wareham N, Bingham S, Welch A, Luben R, Day N(2008). Combined impact of health behaviours and mortality in men and women: The EPIC-Norfolk prospective population study. Obstetrical and Gynecological Survey vol. 63, (6) 376-377.
10.1097/01.ogx.0000314814.70537.a8
Loos RJF, Lindgren CM, Li SX, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM et al.(2008). Common variants near MC4R are associated with fat mass, weight and risk of obesity. NAT GENET vol. 40, (6) 768-775.
10.1038/ng.140
Doblado M, Munroe PB, O'Neill D, Witkowska K, Charchar F, Evans S, Caulfield MJ, Cheeseman CI et al. (2008). Functional studies identify a glucose transporter SLC2A9 as a novel urate transporter. DIABETES. vol. 57, A356-A356.
Myint PK, Luben RN, Wareham NJ, Welch AA, Bingham SA, Khaw KT(2008). Physical activity and fibrinogen concentrations in 23,201 men and women in the EPIC-Norfolk population-based study. Atherosclerosis vol. 198, (2) 419-425.
10.1016/j.atherosclerosis.2007.09.021
Lakshman R, Forouhi N, Luben R, Bingham S, Khaw K, Wareham N, Ong KK(2008). Association between age at menarche and risk of diabetes in adults: Results from the EPIC-Norfolk cohort study. Diabetologia vol. 51, (5) 781-786.
10.1007/s00125-008-0948-5
Weedon MN, Lango H, Lindgren CM, Wallace C, Evans DM, Mangino M, Freathy RM, Perry JRB et al.(2008). Genome-wide association analysis identifies 20 loci that influence adult height. NAT GENET vol. 40, (5) 575-583.
10.1038/ng.121
Purslow LR, Young EH, Wareham NJ, Forouhi N, Brunner EJ, Luben RN, Welch AA, Khaw KT et al.(2008). Socioeconomic position and risk of short-term weight gain: Prospective study of 14,619 middle-aged men and women. BMC Public Health vol. 8,
10.1186/1471-2458-8-112
Ward H, Chapelais G, Kuhnle GGC, Luben R, Khaw KT, Bingham S(2008). Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study. Breast Cancer Research vol. 10, (2)
10.1186/bcr1995
Hunninghake GM, Lasky-Su J, Soto-Quirós ME, Avila L, Liang C, Lake SL, Hudson TJ, Spesny M et al.(2008). Sex-stratified linkage analysis identifies a female-specific locus for IgE to cockroach in Costa Ricans. American Journal of Respiratory and Critical Care Medicine vol. 177, (8) 830-836.
10.1164/rccm.200711-1697OC
Sabb FW, Bearden CE, Glahn DC, Parker DS, Freimer N, Bilder RM(2008). A collaborative knowledge base for cognitive phenomics. Molecular Psychiatry vol. 13, (4) 350-360.
10.1038/sj.mp.4002124
Surtees PG, Wainwright NWJ, Luben RN, Wareham NJ, Bingham SA, Khaw KT(2008). Depression and ischemic heart disease mortality: Evidence from the EPIC-Norfolk United Kingdom prospective cohort study. American Journal of Psychiatry vol. 165, (4) 515-523.
10.1176/appi.ajp.2007.07061018
Hart AR, Luben R, Olsen A, Tjonneland A, Linseisen J, Nagel G, Berglund G, Lindgren S et al.(2008). Diet in the aetiology of ulcerative colitis: A European prospective cohort study. Digestion vol. 77, (1) 57-64.
10.1159/000121412
Hart AR, Luben R, Welch A, Bingham S, Khaw KT(2008). Hormone replacement therapy and symptomatic gallstones - A prospective population study in the EPIC-Norfolk cohort. Digestion vol. 77, (1) 4-9.
10.1159/000113897
Scharf JM, Moorjani P, Fagerness J, Platko JV, Illmann C, Galloway B, Jenike E, Stewart SE et al.(2008). Lack of association between SLITRK1var321 and tourette syndrome in a large family-based sample. Neurology vol. 70, (16) 1495-1496.
10.1212/01.wnl.0000296833.25484.bb
Khaw KT, Wareham N, Bingham S, Welch A, Luben R, Day N(2008). Correction: Combined impact of health behaviours and mortality in men and women: The EPIC-Norfolk prospective population study (PLoS Medecine (2008) 5:1 doi:10.1371/journal.pmed.0050012). PLoS Medicine vol. 5, (3)
10.1371/journal.pmed.0050070
Wang S, Ray N, Rojas W, Parra MV, Bedoya G, Gallo C, Poletti G, Mazzotti G et al.(2008). Geographic patterns of genome admixture in latin American mestizos. PLoS Genetics vol. 4, (3)
10.1371/journal.pgen.1000037
Moayyeri A, Luben RN, Bingham SA, Welch AA, Wareham NJ, Khaw KT(2008). Measured height loss predicts fractures in middle-aged and older men and women: The EPIC-Norfolk prospective population study. Journal of Bone and Mineral Research vol. 23, (3) 425-432.
10.1359/jbmr.071106
Chan MF, Dowsett M, Folkerd E, Wareham N, Luben R, Welch A, Bingham S, Khaw KT(2008). Past oral contraceptive and hormone therapy use and endogenous hormone concentrations in postmenopausal women. Menopause vol. 15, (2) 332-339.
10.1097/gme.0b013e31806458d9
Peters TM, Ekelund U, Leitzmann M, Easton D, Warren R, Luben R, Bingham S, Khaw KT et al.(2008). Physical activity and mammographic breast density in the EPIC-Norfolk cohort study. American Journal of Epidemiology vol. 167, (5) 579-585.
10.1093/aje/kwm350
Sandhu MS, Waterworth DM, Debenham SL, Wheeler E, Papadakis K, Zhao JH, Song K, Yuan X et al.(2008). LDL-cholesterol concentrations: a genome-wide association study. The Lancet vol. 371, (9611) 483-491.
10.1016/S0140-6736(08)60208-1
Sinha S, Myint PK, Luben RN, Khaw KT(2008). Accuracy of death certification and hospital record linkage for identification of incident stroke. BMC Medical Research Methodology vol. 8,
10.1186/1471-2288-8-74
Jarvik L, Larue A, Blacker D, Gatz M, Kawas C, McArdle JJ, Morris JC, Mortimer JA et al.(2008). Children of persons with Alzheimer disease: What does the future hold?. Alzheimer Disease and Associated Disorders vol. 22, (1) 6-20.
10.1097/WAD.0b013e31816653ac
Khaw KT, Wareham N, Bingham S, Welch A, Luben R, Day N(2008). Combined impact of health behaviours and mortality in men and women: The EPIC-Norfolk prospective population study. PLoS Medicine vol. 5, (1) 0039-0047.
10.1371/journal.pmed.0050012
Dobson RJB, Munroe PB, Mein CA, Caulfield MJ, Saqi MAS (2008). Combining protein-protein interaction (PPI) network and sequence attributes for predicting hypertension related proteins. BIOINFORMATICS RESEARCH AND DEVELOPMENT, PROCEEDINGS. Editors: Elloumi, M, Kung, J, Linial, M, Murphy, RF et al., vol. 13, 377-391.
10.1007/978-3-540-70600-7_28
Purslow LR, Sandhu MS, Forouhi N, Young EH, Luben RN, Welch AA, Khaw KT, Bingham SA et al.(2008). Energy intake at breakfast and weight change: Prospective study of 6,764 middle-aged men and women. American Journal of Epidemiology vol. 167, (2) 188-192.
10.1093/aje/kwm309
Wallace C, Newhouse SJ, Braund P, Zhang F, Tobin M, Falchi M, Ahmadi K, Dobson RJ et al.(2008). Genome-wide association study identifies genes for biomarkers of cardiovascular disease: Serum urate and dyslipiclemia. AM J HUM GENET vol. 82, (1) 139-149.
10.1016/j.ajhg.2007.11.001
Stefansson H, Rujescu D, Cichon S, Pietiläinen OPH, Ingason A, Steinberg S, Fossdal R, Sigurdsson E et al.(2008). Large recurrent microdeletions associated with schizophrenia. Nature vol. 455, (7210) 232-236.
10.1038/nature07229
Myint PK, Luben RN, Welch AA, Bingham SA, Wareham NJ, Khaw KT(2008). Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer-Norfolk prospective population study. American Journal of Clinical Nutrition vol. 87, (1) 64-69.
10.1093/ajcn/87.1.64
Surtees PG, Wainwright NWJ, Luben RN, Wareham NJ, Bingham SA, Khaw KT(2008). Psychological distress, major depressive disorder, and risk of strokesymbol. Neurology vol. 70, (10) 788-794.
10.1212/01.wnl.0000304109.18563.81
Myint PK, Sinha S, Luben RN, Bingham SA, Wareham NJ, Khaw KT(2008). Risk factors for first-ever stroke in the EPIC-Norfolk prospective population-based study. European Journal of Preventive Cardiology vol. 15, (6) 663-669.
10.1097/HJR.0b013e32830fe465
Nejentsev S, Howson JMM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M et al.(2007). Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature vol. 450, (7171) 887-892.
10.1038/nature06406
Wu K, Bowman R, Welch AA, Luben RN, Wareham N, Khaw KT, Bingham SA(2007). Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: The EPIC Norfolk study. European Heart Journal vol. 28, (23) 2930-2936.
10.1093/eurheartj/ehm482
Canoy D, Boekholdt SM, Wareham N, Luben R, Welch A, Bingham S, Buchan I, Day N et al.(2007). Body fat distribution and risk of coronary heart disease in men and women in the european prospective investigation into cancer and nutrition in norfolk cohort: A population-based prospective study. Circulation vol. 116, (25) 2933-2943.
10.1161/CIRCULATIONAHA.106.673756
Rana JS, Boekholdt SM, Ridker PM, Jukema JW, Luben R, Bingham SA, Day NE, Wareham NJ et al.(2007). Differential leucocyte count and the risk of future coronary artery disease in healthy men and women: The EPIC-Norfolk Prospective Population Study. Journal of Internal Medicine vol. 262, (6) 678-689.
10.1111/j.1365-2796.2007.01864.x
Khaw KT, Dowsett M, Folkerd E, Bingham S, Wareham N, Luben R, Welch A, Day N(2007). Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) prospective population study. Circulation vol. 116, (23) 2694-2701.
10.1161/CIRCULATIONAHA.107.719005
Burke B, Gungadoo J, Marçano ACB, Newhouse SJ, Shiel J, Caulfield MJ, Munroe PB(2007). Monogenic Forms of Human Hypertension. Comprehensive Hypertension,
Freel EM, Ingram M, Friel EC, Fraser R, Brown M, Samani NJ, Caulfield M, Munroe P et al.(2007). Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. CLIN ENDOCRINOL vol. 67, (6) 832-838.
10.1111/j.1365-2265.2007.02971.x
Thomson W, Barton A, Ke X, Eyre S, Hinks A, Bowes J, Donn R, Symmons D et al.(2007). Rheumatoid arthritis association at 6q23. Nature Genetics vol. 39, (12) 1431-1433.
10.1038/ng.2007.32
Wallace C, Newhouse SJ, Braund P, Zhang F, Tobin M, Falchi M, Ahmadi K, Dobson RJ et al. (2007). Discovery of novel genes for serum urate and low-density lipoprotein cholesterol - Two biomarkers of cardiovascular disease. CIRCULATION RESEARCH. vol. 101, 1208-1208.
Newhouse SJ, Wallace C, Hoti M, Dobson RJ, Farrall M, Brown M, Samani NJ, Dominiczak A et al. (2007). Novel associations of the Wnk1 gene with risk for essential hypertension and electrolyte homeostasis. CIRCULATION RESEARCH. vol. 101, 1208-1208.
Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI et al.(2007). Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics vol. 39, (11) 1329-1337.
10.1038/ng.2007.17
Wallace C, Dobson RJ, Munroe PB, Caulfield MJ(2007). Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates. Genome Res vol. 17, (11) 1596-1602.
10.1101/gr.5996407
Freimer NB, Service SK, Ophoff RA, Jasinska AJ, McKee K, Villeneuve A, Belisle A, Bailey JN et al.(2007). A quantitative trait locus for variation in dopamine metabolism mapped in a primate model using reference sequences from related species. Proceedings of the National Academy of Sciences of the United States of America vol. 104, (40) 15811-15816.
10.1073/pnas.0707640104
Birjmohun RS, Dallinga-Thie GM, Kuivenhoven JA, Stroes ESG, Otvos JD, Wareham NJ, Luben R, Kastelein JJP et al.(2007). Apolipoprotein A-II is inversely associated with risk of future coronary artery disease. Circulation vol. 116, (18) 2029-2035.
10.1161/CIRCULATIONAHA.107.704031
Padmanabhan S, Davies E, MacKenzie SM, Lim W, Barr M, Friel EC, Munroe PB, Brown MJ et al.(2007). Association of the CYP11B1 and CYP11B2 gene polymorphisms with hypertension in the British Genetics of Hypertension case-control study. J HUM HYPERTENS vol. 21, (10) 837-837.
Newhouse S, Wallace C, Hoti M, Burke B, Marcano A, Onipinla A, Dobson R, Mein C et al. (2007). Association of the WNK1 gene with essential hypertension, blood pressure variability and serum and urine electrolytes. J HUM HYPERTENS. vol. 21, 831-831.
Wainwright NWJ, Surtees PG, Welch AA, Luben RN, Khaw KT, Bingham SA(2007). Healthy lifestyle choices: Could sense of coherence aid health promotion?. Journal of Epidemiology and Community Health vol. 61, (10) 871-876.
10.1136/jech.2006.056275
Surtees PG, Wainwright NWJ, Willis-Owen SAG, Sandhu MS, Luben R, Day NE, Flint J(2007). The brain-derived neurotrophic factor Val66Met polymorphism is associated with sense of coherence in a non-clinical community sample of 7335 adults. Journal of Psychiatric Research vol. 41, (8) 707-710.
10.1016/j.jpsychires.2006.05.015
Padmanabhan S, Menni C, Delles C, Munroe PB, Brown MJ, Samani NJ, Farrall M, Dobson R et al. (2007). Urinary albumin excretion in hypertensive siblings in the British Genetics of Hypertension study. J HUM HYPERTENS. vol. 21, 843-843.
Athos EA, Levinson B, Kistler A, Zemansky J, Bostrom A, Freimer N, Gitschier J(2007). Dichotomy and perceptual distortions in absolute pitch ability. Proceedings of the National Academy of Sciences of the United States of America vol. 104, (37) 14795-14800.
10.1073/pnas.0703868104
Marcano ACB, Burke B, Gungadoo J, Wallace C, Kaisaki PJ, Woon PY, Farrall M, Clayton D et al.(2007). Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension. J MED GENET vol. 44, (9) Article 603,
10.1136/jmg.2007.049718
Bingham S, Luben R, Welch A, Tasevska N, Wareham N, Khaw KT(2007). Epidemiologic assessment of sugars consumption using biomarkers: Comparisons of obese and nonobese individuals in the European Prospective Investigation of Cancer Norfolk. Cancer Epidemiology Biomarkers and Prevention vol. 16, (8) 1651-1654.
10.1158/1055-9965.EPI-06-1050
Surtees PG, Wainwright NWJ, Willis-Owen SAG, Sandhu MS, Luben R, Day NE, Flint J(2007). No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults. Journal of Psychiatric Research vol. 41, (5) 404-409.
10.1016/j.jpsychires.2006.01.004
Meuwese MC, Stroes ESG, Hazen SL, van Miert JN, Kuivenhoven JA, Schaub RG, Wareham NJ, Luben R et al.(2007). Serum Myeloperoxidase Levels Are Associated With the Future Risk of Coronary Artery Disease in Apparently Healthy Individuals. The EPIC-Norfolk Prospective Population Study. Journal of the American College of Cardiology vol. 50, (2) 159-165.
10.1016/j.jacc.2007.03.033
Easton DF, Pooley KA, Dunning AM, Pharoah PDP, Thompson D, Ballinger DG, Struewing JP, Morrison J et al.(2007). Genome-wide association study identifies novel breast cancer susceptibility loci. Nature vol. 447, (7148) 1087-1093.
10.1038/nature05887
Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI et al.(2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. NATURE vol. 447, (7145) 661-678.
10.1038/nature05911
Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G et al.(2007). Replicating genotype-phenotype associations. Nature vol. 447, (7145) 655-660.
10.1038/447655a
Myint PK, Luben RN, Surtees PG, Wainwright NWJ, Welch AA, Bingham SA, Wareham NJ, Smith RD et al.(2007). Self-reported mental health-related quality of life and mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): A prospective population study. Psychosomatic Medicine vol. 69, (5) 410-414.
10.1097/psy.0b013e318068fcd4
Melzer D, Frayling TM, Murray A, Hurst AJ, Harries LW, Song H, Khaw KT, Luben R et al.(2007). A common variant of the p16<sup>INK4a</sup> genetic region is associated with physical function in older people. Mechanisms of Ageing and Development vol. 128, (5-6) 370-377.
10.1016/j.mad.2007.03.005
Jasinska AJ, Service S, Levinson M, Slaten E, Lee O, Sobel E, Fairbanks LA, Bailey JN et al.(2007). A genetic linkage map of the vervet monkey (Chlorocebus aethiops sabaeus). Mammalian Genome vol. 18, (5) 347-360.
10.1007/s00335-007-9026-4
Surtees PG, Wainwright NWJ, Luben RL, Wareham NJ, Bingham SA, Khaw KT(2007). Adaptation to social adversity is associated with stroke incidence: Evidence from the EPIC-Norfolk prospective cohort study. Stroke vol. 38, (5) 1447-1453.
10.1161/STROKEAHA.106.473116
Mallat Z, Benessiano J, Simon T, Ederhy S, Sebella-Arguelles C, Cohen A, Huart V, Wareham NJ et al.(2007). Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: The EPIC-NORFOLK study. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 27, (5) 1177-1183.
10.1161/ATVBAHA.107.139352
Forouhi NG, Harding AH, Allison M, Sandhu MS, Welch A, Luben R, Bingham S, Khaw KT et al.(2007). Elevated serum ferritin levels predict new-onset type 2 diabetes: Results from the EPIC-Norfolk prospective study. Diabetologia vol. 50, (5) 949-956.
10.1007/s00125-007-0604-5
Low YL, Dunning AM, Dowsett M, Folkerd E, Doody D, Taylor J, Bhaniani A, Luben R et al.(2007). Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants. Cancer Epidemiology Biomarkers and Prevention vol. 16, (5) 1009-1016.
10.1158/1055-9965.EPI-06-0899
Van Der Steeg WA, Boekholdt SM, Stein EA, El-Harchaoui K, Stroes ESG, Sandhu MS, Wareham NJ, Jukema JW et al.(2007). Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: A case-control analysis in EPIC-Norfolk. Annals of Internal Medicine vol. 146, (9) 640-648.
10.7326/0003-4819-146-9-200705010-00007
Chan MF, Dowsett M, Folkerd E, Bingham S, Wareham N, Luben R, Welch A, Khaw KT(2007). Usual physical activity and endogenous sex hormones in postmenopausal women: The European prospective investigation into cancer-Norfolk population study. Cancer Epidemiology Biomarkers and Prevention vol. 16, (5) 900-905.
10.1158/1055-9965.EPI-06-0745
Baynes C, Healey CS, Pooley KA, Scollen S, Luben RN, Thompson DJ, Pharoah PDP, Easton DF et al.(2007). Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk. Breast Cancer Research vol. 9, (2)
10.1186/bcr1669
Samuelson DJ, Hesselson SE, Aperavich BA, Zan Y, Haag JD, Trentham-Dietz A, Hampton JM, Mau B et al.(2007). Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk. Proceedings of the National Academy of Sciences of the United States of America vol. 104, (15) 6299-6304.
10.1073/pnas.0701687104
Service S, Sabatti C, Freimer N, Karayiorgou M, Roos JL, Pretorious H, Bedoya G, Ospina J et al.(2007). Tag SNPs chosen from HapMap perform well in several population isolates. Genetic Epidemiology vol. 31, (3) 189-194.
10.1002/gepi.20201
Mehan MR, Almonte M, Slaten E, Freimer NB, Rao PN, Ophoff RA(2007). Analysis of segmental duplications reveals a distinct pattern of continuation-of-synteny between human and mouse genomes. Human Genetics vol. 121, (1) 93-100.
10.1007/s00439-006-0277-z
Pharoah PDP, Tyrer J, Dunning AM, Easton DF, Ponder BAJ, Abraham J, Al-Zahrani A, Baynes C et al.(2007). Association between common variation in 120 candidate genes and breast cancer risk. PLoS Genetics vol. 3, (3) 0401-0406.
10.1371/journal.pgen.0030042
Hersh CP, Soto-Quirós ME, Avila L, Lake SL, Liang C, Fournier E, Spesny M, Sylvia JS et al.(2007). Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica. Thorax vol. 62, (3) 224-230.
10.1136/thx.2006.067934
Freimer NB, Sabatti C(2007). Human genetics: Variants in common diseases. Nature vol. 445, (7130) 828-830.
10.1038/nature05568
Myint PK, Sinha S, Wareham NJ, Bingham SA, Luben RN, Welch AA, Khaw KT(2007). Glycated hemoglobin and risk of stroke in people without known diabetes in the European Prospective Investigation Into Cancer (EPIC)-Norfolk prospective population study: A threshold relationship?. Stroke vol. 38, (2) 271-275.
10.1161/01.STR.0000254549.75763.5f
Myint PK, Surtees PG, Wainwright NWJ, Wareham NJ, Bingham SA, Luben RN, Welch AA, Smith RD et al.(2007). Modifiable lifestyle behaviors and functional health in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study. Preventive Medicine vol. 44, (2) 109-116.
10.1016/j.ypmed.2006.09.007
Raby BA, Soto-Quiros ME, Avila L, Lake SL, Murphy A, Liang C, Fournier E, Spesny M et al.(2007). Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica. Human Molecular Genetics vol. 16, (3) 243-253.
10.1093/hmg/ddl447
Mathews CA, Jang KL, Herrera LD, Lowe TL, Budman CL, Erenberg G, Naarden A, Bruun RD et al.(2007). Tic Symptom Profiles in Subjects with Tourette Syndrome from two Genetically Isolated Populations. Biological Psychiatry vol. 61, (3) 292-300.
10.1016/j.biopsych.2006.02.009
Kerner B, Brugman DL, Freimer NB(2007). Evidence of linkage to psychosis on chromosome 5q33-34 in pedigrees ascertained for bipolar disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 144, (1) 74-78.
10.1002/ajmg.b.30402
Arsenault BJ, Lemieux I, Després JP, Wareham NJ, Luben R, Kastelein JJP, Khaw KT, Boekholdt SM(2007). Cholesterol levels in small LDL particles predict the risk of coronary heart disease in the EPIC-Norfolk prospective population study. European Heart Journal vol. 28, (22) 2770-2777.
10.1093/eurheartj/ehm390
Myint PK, Welch AA, Bingham SA, Surtees PG, Wainwright NWJ, Luben RN, Wareham NJ, Smith RD et al.(2007). Fruit and vegetable consumption and self-reported functional health in men and women in the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk): A population-based cross-sectional study. Public Health Nutrition vol. 10, (1) 34-41.
10.1017/S1368980007222608
Pauls D, Cath D, Heutink P, Grados M, Singer HS, Walkup JT, Illmann C, Scharf JM et al.(2007). Genome scan for tourette disorder in affected-sibling-pair and multigenerational families. American Journal of Human Genetics vol. 80, (2) 265-272.
10.1086/511052
Myint PK, Surtees PG, Wainwright NWJ, Luben RN, Welch AA, Bingham SA, Wareham NJ, Khaw KT(2007). Physical health-related quality of life predicts stroke in the EPIC-Norfolk. Neurology vol. 69, (24) 2243-2248.
10.1212/01.wnl.0000296010.21252.78
Pinedo S, Vissers MN, Von Bergmann K, Elharchaoui K, Lütjohann D, Luben R, Wareham NJ, Kastelein JJP et al.(2007). Plasma levels of plant sterols and the risk of coronary artery disease: The prospective EPIC-Norfolk Population Study. Journal of Lipid Research vol. 48, (1) 139-144.
10.1194/jlr.M600371-JLR200
Barr M, MacKenzie SM, Friel EC, Holloway CD, Wilkinson DM, Brain NJR, Ingram MC, Fraser R et al.(2007). Polymorphic variation in the 11 beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency. HYPERTENSION vol. 49, (1) 113-119.
10.1161/01.HYP.0000249904.93940.7a
Celedon JC, Soto-Quiros ME, Avila L, Lake SL, Liang C, Fournier E, Spesny M, Hersh CP et al.(2007). Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica. Human Genetics vol. 120, (5) 691-699.
10.1007/s00439-006-0255-5
Heude B, Ong KK, Luben R, Wareham NJ, Sandhu MS(2007). Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women. Journal of Clinical Endocrinology and Metabolism vol. 92, (7) 2734-2738.
10.1210/jc.2006-1948
Benusiglio PR, Pharoah PD, Smith PL, Lesueur F, Conroy D, Luben RN, Dew G, Jordan C et al.(2006). HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer. British Journal of Cancer vol. 95, (12) 1689-1695.
10.1038/sj.bjc.6603473
Keller TT, Nagel C, Te Velthuis H, Gerdes VEA, Wareham NJ, Bingham SA, Luben R, Hack CE et al.(2006). Erratum: (Journal of Thrombosis and Haemostasis). Journal of Thrombosis and Haemostasis vol. 4, (12)
10.1111/j.1538-7836.2006.02293.x
Myint PK, Welch AA, Bingham SA, Luben RN, Wareham NJ, Day NE, Khaw KT(2006). Habitual fish consumption and risk of incident stroke: The European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study. Public Health Nutrition vol. 9, (7) 882-888.
10.1017/PHN2006942
Wang H, Lin CH, Service S, Chen Y, Freimer N, Sabatti C, Karayiorgou M, Roos JL et al.(2006). Linkage disequilibrium and haplotype homozygosity in population samples genotyped at a high marker density. Human Heredity vol. 62, (4) 175-189.
10.1159/000096599
Low YL, Taylor JI, Grace PB, Mulligan AA, Welch A, Scollen S, Dunning AM, Luben RN et al.(2006). Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk. Nutrition and Cancer vol. 56, (1) 31-39.
10.1207/s15327914nc5601_5
Canoy D, Wareham N, Luben R, Welch A, Bingham S, Day N, Khaw KT(2006). Serum lipid concentration in relation to anthropometric indices of central and peripheral fat distribution in 20,021 British men and women: Results from the EPIC-Norfolk population-based cohort study. Atherosclerosis vol. 189, (2) 420-427.
10.1016/j.atherosclerosis.2005.12.027
Keen-Kim D, Mathews CA, Reus VI, Lowe TL, Herrera LD, Budman CL, Gross-Tsur V, Pulver AE et al.(2006). Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses. Human Molecular Genetics vol. 15, (22) 3324-3328.
10.1093/hmg/ddl408
Herzberg I, Jasinska A, García J, Jawaheer D, Service S, Kremeyer B, Duque C, Parra MV et al.(2006). Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34. Human Molecular Genetics vol. 15, (21) 3146-3153.
10.1093/hmg/ddl254
Keller TT, Nagel C, Te Velthuis H, Gerdes VEA, Wareham NJ, Bingham SA, Luben R, Hack CE et al.(2006). Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: The EPIC-Norfolk prospective population study. Journal of Thrombosis and Haemostasis vol. 4, (11) 2391-2396.
10.1111/j.1538-7836.2006.02190.x
Delles C, Braga-Marcano AC, Munroe PB, Padmanabhan S, McClure JD, Brain NJ, Brown MJ, Samani NJ et al. (2006). Association between variants of the human GSTM gene family and hypertension. HYPERTENSION. vol. 48, E27-E27.
Myint PK, Luben RN, Wareham NJ, Welch AA, Bingham SA, Day NE, Khaw KT(2006). Combined work and leisure physical activity and risk of stroke in men and women in the European prospective investigation into cancer-Norfolk prospective population study. Neuroepidemiology vol. 27, (3) 122-129.
10.1159/000095551
Padmanabhan S, Hastie CE, Wallace C, Munroe PB, Dobson R, Brown M, Samani NJ, Clayton D et al. (2006). Familial atherosclerotic disease and hypertension localised to chromosome 7p in the British genetics of hypertension study. HYPERTENSION. vol. 48, E98-E98.
Keller TT, Van Leuven SI, Meuwese MC, Wareham NJ, Luben R, Stroes ES, Hack CE, Levi M et al.(2006). Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 26, (10) 2345-2350.
10.1161/01.ATV.0000240517.69201.77
Vaessen SFC, Schaap FG, Kuivenhoven JA, Groen AK, Hutten BA, Boekholdt SM, Hattori H, Sandhu MS et al.(2006). Apolipoprotein A-V, triglycerides and risk of coronary artery disease: The prospective Epic-Norfolk Population Study. Journal of Lipid Research vol. 47, (9) 2064-2070.
10.1194/jlr.M600233-JLR200
Low YL, Dunning AM, Dowsett M, Luben RN, Khaw KT, Wareham NJ, Bingham SA(2006). Implications of gene-environment interaction in studies of gene variants in breast cancer: An example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene. Cancer Research vol. 66, (18) 8980-8983.
10.1158/0008-5472.CAN-06-2432
Boekholdt SM, Meuwese MC, Day NE, Luben R, Welch A, Wareham NJ, Khaw KT(2006). Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: The EPIC-Norfolk prospective population study. British Journal of Nutrition vol. 96, (3) 516-522.
10.1079/BJN20061846
Warren R, Skinner J, Sala E, Denton E, Dowsett M, Folkerd E, Healey CS, Dunning A et al.(2006). Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women. Cancer Epidemiology Biomarkers and Prevention vol. 15, (8) 1502-1508.
10.1158/1055-9965.EPI-05-0828
Boekholdt SM, Hack CE, Sandhu MS, Luben R, Bingham SA, Wareham NJ, Peters RJG, Jukema JW et al.(2006). C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: The EPIC-Norfolk prospective population study 1993-2003. Atherosclerosis vol. 187, (2) 415-422.
10.1016/j.atherosclerosis.2005.09.023
Boekholdt SM, Sandhu MS, Wareham NJ, Luben R, Reitsma PH, Khaw KT(2006). Fibrinogen plasma levels modify the association between the factor XIII Val34Leu variant and risk of coronary artery disease: The EPIC-Norfolk prospective population study. Journal of Thrombosis and Haemostasis vol. 4, (10) 2204-2209.
10.1111/j.1538-7836.2006.02154.x
Cebrian A, Pharoah PD, Ahmed S, Ropero S, Fraga MF, Smith PL, Conroy D, Luben R et al.(2006). Genetic variants in epigenetic genes and breast cancer risk. Carcinogenesis vol. 27, (8) 1661-1669.
10.1093/carcin/bgi375
Keen-Kim D, Freimer NB(2006). Genetics and epidemiology of Tourette syndrome. Journal of Child Neurology vol. 21, (8) 665-671.
10.1177/08830738060210081101
Wallace C, Xue M-Z, Newhouse SJ, Marcano ACB, Onipinla AK, Burke B, Gungadoo J, Dobson RJ et al.(2006). Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension. Am J Hum Genet vol. 79, (2) 323-331.
10.1086/506370
Khaw KT, Jakes R, Bingham S, Welch A, Luben R, Day N, Wareham N(2006). Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The European Prospective Investigation into Cancer in Norfolk prospective population study. International Journal of Epidemiology vol. 35, (4) 1034-1043.
10.1093/ije/dyl079
Jakszyn P, Bingham S, Pera G, Agudo A, Luben R, Welch A, Boeing H, del Giudice G et al.(2006). Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study. Carcinogenesis vol. 27, (7) 1497-1501.
10.1093/carcin/bgl019
Kataoka M, Warren R, Luben R, Camus J, Denton E, Sala E, Day N, Khaw KT(2006). How predictive is breast arterial calcification of cardiovascular disease and risk factors when found at screening mammography?. American Journal of Roentgenology vol. 187, (1) 73-80.
10.2214/AJR.05.0365
Munroe PB, Wallace C, Xue M-Z, Marçano ACB, Dobson RJ, Onipinla AK, Burke B, Gungadoo J et al.(2006). Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British Genetics of Hypertension Study. Hypertension vol. 48, (1) 105-111.
10.1161/01.HYP.0000228324.74255.f1
Lesueur F, Song H, Ahmed S, Luccarini C, Jordan C, Luben R, Easton DF, Dunning AM et al.(2006). Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population. British Journal of Cancer vol. 94, (12) 1921-1926.
10.1038/sj.bjc.6603160
Woods RP, Freimer NB, De Young JA, Fears SC, Sicotte NL, Service SK, Valentino DJ, Toga AW et al.(2006). Normal variants of Microcephalin and ASPM do not account for brain size variability. Human Molecular Genetics vol. 15, (12) 2025-2029.
10.1093/hmg/ddl126
Service S, Molina J, DeYoung J, Jawaheer D, Aldana I, Vu T, Bejarano J, Fournier E et al.(2006). Results of a SNP genome screen in a large Costa Rican pedigree segregating for severe bipolar disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 141, (4) 367-373.
10.1002/ajmg.b.30323
Bearden CE, Freimer NB(2006). Endophenotypes for psychiatric disorders: ready for primetime?. Trends in Genetics vol. 22, (6) 306-313.
10.1016/j.tig.2006.04.004
Padmanabhan S, Wallace C, McBride MW, Munroe PB, Dobson R, Brown M, Samani NJ, Clayton D et al. (2006). Genomewide linkage analysis for loci affecting electrocardiographic LV mass. JOURNAL OF HYPERTENSION. vol. 24, S330-S330.
Myint PK, Luben RN, Surtees PG, Wainwright NWJ, Welch AA, Bingham SA, Day NE, Wareham NJ et al.(2006). Relation Between Self-Reported Physical Functional Health and Chronic Disease Mortality in Men And Women in the European Prospective Investigation Into Cancer (EPIC-Norfolk): A Prospective Population Study. Annals of Epidemiology vol. 16, (6) 492-500.
10.1016/j.annepidem.2005.04.005
Delles C, Marcano ACB, Munroe PB, Padmanabhan S, McClure JD, Brain NJ, Brown MJ, Samani NJ et al. (2006). Variants of the human mu type glutathione-s-transferase (GSTM) gene family are associated with hypertension. JOURNAL OF HYPERTENSION. vol. 24, S13-S13.
Patel BD, Welch AA, Bingham SA, Luben RN, Day NE, Khaw KT, Lomas DA, Wareham NJ(2006). Dietary antioxidants and asthma in adults. Thorax vol. 61, (5) 388-393.
10.1136/thx.2004.024935
Service S, DeYoung J, Karayiorgou M, Roos JL, Pretorious H, Bedoya G, Ospina J, Ruiz-Linares A et al.(2006). Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nature Genetics vol. 38, (5) 556-560.
10.1038/ng1770
Myint PK, Welch AA, Luben RN, Wainwright NWJ, Surtees PG, Bingham SA, Wareham NJ, Smith RD et al.(2006). Obesity indices and self-reported functional health in men and women in the EPIC-Norfolk. Obesity vol. 14, (5) 884-893.
10.1038/oby.2006.102
Dobson RJ, Munroe PB, Caulfield MJ, Saqi MA(2006). Predicting deleterious nsSNPs: an analysis of sequence and structural attributes. BMC Bioinformatics vol. 7,
10.1186/1471-2105-7-217
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19176
Bell JT, Wallace C, Dobson R, Wiltshire S, Mein C, Pembroke J, Brown M, Clayton D et al.(2006). Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension. HUM MOL GENET vol. 15, (8) 1365-1374.
10.1093/hmg/ddl058
Padmanabhan S, Wallace C, Munroe PB, Dobson R, Brown M, Samani N, Clayton D, Farrall M et al. (2006). Chromosome 2p shows significant linkage to antihypertensive response in the British genetics of hypertension study. HYPERTENSION. vol. 47, 603-608.
10.1161/01.HYP.0000197947.62601.9d
Binder A, Garcia E, Wallace C, Kazeem G, Ben-Shlomo Y, Yarnell J, Brown P, Caulfield M et al.(2006). Haplotypes of the beta-2 adrenergic receptor associate with high diastolic blood pressure in the Caerphilly prospective study. J HYPERTENS vol. 24, (3) 471-477.
10.1097/01.hjh.0000209983.28735.33
Rip J, Nierman MC, Wareham NJ, Luben R, Bingham SA, Day NE, Van Miert JNI, Hutten BA et al.(2006). Serum lipoprotein lipase concentration and risk for future coronary artery disease: The EPIC-Norfolk prospective population study. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 26, (3) 637-642.
10.1161/01.ATV.0000201038.47949.56
Glatt C, Almonte M, Taylor T, Edwards RH, Freimer N, Tanner C(2006). Structural variants the vesicular monoamine transpoter do not contribute to sporadic Parkinson's disease [1]. Movement Disorders vol. 21, (3) 426-427.
10.1002/mds.20798
Myint PK, Welch AA, Bingham SA, Luben RN, Wareham NJ, Day NE, Khaw KT(2006). Smoking predicts long-term mortality in stroke: The European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study. Preventive Medicine vol. 42, (2) 128-131.
10.1016/j.ypmed.2005.11.014
Surtees PG, Wainwright NWJ, Willis-Owen SAG, Luben R, Day NE, Flint J(2006). Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder. Biological Psychiatry vol. 59, (3) 224-229.
10.1016/j.biopsych.2005.07.014
Cebrian A, Pharoah PD, Ahmed S, Smith PL, Luccarini C, Luben R, Redman K, Munday H et al.(2006). Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. Cancer Research vol. 66, (2) 1225-1233.
10.1158/0008-5472.CAN-05-1857
Mathews CA, Bimson B, Lowe TL, Herrera LD, Budman CL, Erenberg G, Naarden A, Bruun RD et al.(2006). Association between maternal smoking and increased symptom severity in Tourette's syndrome. American Journal of Psychiatry vol. 163, (6) 1066-1073.
10.1176/ajp.2006.163.6.1066
Myint PK, Luben RN, Welch AA, Bingham SA, Wareham NJ, Khaw KT(2006). Effect of age on the relationship of occupational social class with prevalence of modifiable cardiovascular risk factors and cardiovascular diseases: A population-based cross-sectional study from European Prospective Investigation into Cancer - Norfolk (EPIC-Norfolk). Gerontology vol. 52, (1) 51-58.
10.1159/000089826
Al-Zahrani A, Sandhu MS, Luben RN, Thompson D, Baynes C, Pooley KA, Luccarini C, Munday H et al.(2006). IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer. Human Molecular Genetics vol. 15, (1) 1-10.
10.1093/hmg/ddi398
Surtees PG, Wainwright NWJ, Luben R, Khaw KT, Day NE(2006). Mastery, sense of coherence, and mortality: Evidence of independent associations from the EPIC-Norfolk prospective cohort study. Health Psychology vol. 25, (1) 102-110.
10.1037/0278-6133.25.1.102
Boekholdt SM, Sandhu MS, Day NE, Luben R, Bingham SA, Peters RJG, Wareham NJ, Khaw KT(2006). Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: The EPIC€“Norfolk prospective population study. European Journal of Preventive Cardiology vol. 13, (6) 970-976.
10.1097/01.hjr.0000209811.97948.07
Myint PK, Luben RN, Surtees PG, Wainwright NWJ, Welch AA, Bingham SA, Wareham NJ, Day NE et al.(2005). Erratum: "Respiratory function and self-reported functional health: Epic-Norfolk population study" (European Respiratory Journal (2005) vol. 26 (494-502)). European Respiratory Journal vol. 26, (6)
10.1183/09031936.05.00116405
Jarvik LF, La Rue A, Gokhman I, Harrison T, Holt L, Steh B, Harker J, Larson S et al. (2005). Middle-aged children of Alzheimer parents, a pilot study: Stable neurocognitive performance at 20-year follow-up. Journal of Geriatric Psychiatry and Neurology. vol. 18, 187-191.
10.1177/0891988705281862
Canoy D, Wareham N, Welch A, Bingham S, Luben R, Day N, Khaw KT(2005). Plasma ascorbic acid concentrations and fat distribution in 19 068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study. American Journal of Clinical Nutrition vol. 82, (6) 1203-1209.
10.1093/ajcn/82.6.1203
Tobin MD, Raleigh SM, Newhouse S, Braund P, Bodycote C, Ogleby J, Cross D, Gracey J et al.(2005). Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population. CIRCULATION vol. 112, (22) 3423-3429.
10.1161/CIRCULATIONHA.105.555474
Padmanabhan S, Wallace C, Munroe PB, Brown M, Samani N, Clayton D, Farrall M, Webster J et al. (2005). Chromosome 2p shows genome wide significant linkage to of anti-hypertensive medication response in the British genetics of hypertension (BRIGHT) study. HYPERTENSION. vol. 46, 886-886.
Wallace C, Xue MZ, Dobson R, Marcano C, Gungadoo J, Burke B, Onipinla A, Newhouse S et al. (2005). Loci on chromosomes 5p and 20q are linked to multiple hypertension phenotypes in the BRItish genetics of Hypertension (BRIGHT) study. HYPERTENSION. vol. 46, 877-877.
Cebrian A, Lesueur F, Martin S, Leyland J, Ahmed S, Luccarini C, Smith PL, Luben R et al.(2005). Polymorphisms in the initiators of RET (Rearranged during transfection) signaling pathway and susceptibility to sporadic medullary thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism vol. 90, (11) 6268-6274.
10.1210/jc.2004-2449
Padmanabhan S, Munroe PB, Brown M, Clayton D, Farrall M, Webster J, Lathrop M, Caulfield M et al. (2005). Chromosome 2p shows genome wide significant linkage to anti-hypertensive medication response in the British genetics hypertension (BRIGHT) study. HYPERTENSION. vol. 46, 886-886.
Munroe PB, Wallace C, Mein C, Dobson R, Xue M, Marcano C, Burke B, Gungadoo J et al. (2005). Enhanced support for linkage to chromosome 5q13.1 and hypertension in the British Genetics of Hypertension (BRIGHT) study. HYPERTENSION. vol. 46, 892-892.
Wallace C, Xue MZ, Dobson R, Marcano C, Gungadoo J, Burke B, Onipinla A, Newhouse S et al. (2005). Loci on chromosomes 5p and 20q are linked to multiple hypertension phenotypes in the BRItish Genetics of HyperTension (BRIGHT) study. HYPERTENSION. vol. 46, 877-877.
Xue MZ, Wallace C, Dobson R, Garcia E, Kazeem G, Gardener G, Needham E, Mattu R et al. (2005). Variants and haplotypes of the angiotensinogen gene are associated with hypertension in the Caerphilly Prospective Study. HYPERTENSION. vol. 46, 904-904.
Freimer NB, Sabatti C(2005). Guidelines for association studies in Human Molecular Genetics. Human Molecular Genetics vol. 14, (17) 2481-2483.
10.1093/hmg/ddi251
Sandhu MS, Hende B, Young EH, Luben R, Luan J, Khaw KT, Todd J, Wareham NJ(2005). INS VNTR class genotype and indexes of body size and obesity: Population-based studies of 7,999 middle-aged men and women. Diabetes vol. 54, (9) 2812-2815.
10.2337/diabetes.54.9.2812
Myint PK, Luben RN, Surtees PG, Wainwright NWJ, Welch AA, Bingham SA, Wareham NJ, Day NE et al.(2005). Respiratory function and self-reported functional health: EPIC-Norfolk population study. European Respiratory Journal vol. 26, (3) 494-502.
10.1183/09031936.05.00023605
Ishihara LS, Khaw KT, Luben R, Bingham S, Welch A, Day N, Brayne C(2005). Self-reported parkinsonian symptoms in the EPIC-Norfolk cohort. BMC Neurology vol. 5,
10.1186/1471-2377-5-15
Lesueur F, Pharoah PD, Laing S, Ahmed S, Jordan C, Smith PL, Luben R, Wareham NJ et al.(2005). Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer. Human Molecular Genetics vol. 14, (16) 2349-2356.
10.1093/hmg/ddi237
Benusiglio PR, Lesueur F, Luccarini C, McIntosh J, Luben RN, Smith P, Dunning A, Easton DF et al.(2005). Common variation in EMSY and risk of breast and ovarian cancer: A case-control study using HapMap tagging SNPs. BMC Cancer vol. 5,
10.1186/1471-2407-5-81
Newhouse SJ, Wallace C, Dobson R, Mein C, Pembroke J, Farrall M, Clayton D, Brown M et al.(2005). Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Hum Mol Genet vol. 14, (13) 1805-1814.
10.1093/hmg/ddi187
Jenab M, Bingham S, Ferrari P, Friesen MD, Al-Delaimy WK, Luben R, Wareham N, Khaw KT et al.(2005). Long-term cryoconservation and stability of vitamin C in serum samples of the European prospective investigation into cancer and nutrition. Cancer Epidemiology Biomarkers and Prevention vol. 14, (7) 1837-1840.
10.1158/1055-9965.EPI-05-0061
Marcano ACB, Onipinla AK, Caulfield MJ, Munroe PB(2005). Recent advances in the identification of genes for human hypertension. Expert Rev Cardiovasc Ther vol. 3, (4) 733-741.
10.1586/14779072.3.4.733
Michels KB, Welch AA, Luben R, Bingham SA, Day NE(2005). Measurement of fruit and vegetable consumption with diet questionnaires and implications for analyses and interpretation. American Journal of Epidemiology vol. 161, (10) 987-994.
10.1093/aje/kwi115
Surtees PG, Wainwright NWJ, Luben R, Day NE, Khaw KT(2005). Prospective cohort study of hostility and the risk of cardiovascular disease mortality. International Journal of Cardiology vol. 100, (1) 155-161.
10.1016/j.ijcard.2005.01.014
Boekholdt SM, Keller TT, Wareham NJ, Luben R, Bingham SA, Day NE, Sandhu MS, Jukema JW et al.(2005). Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: The EPIC-Norfolk prospective population study. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 25, (4) 839-846.
10.1161/01.ATV.0000157933.19424.b7
Welch AA, Luben R, Khaw KT, Bingham SA(2005). The CAFE computer program for nutritional analysis of the EPIC-Norfolk food frequency questionnaire and identification of extreme nutrient values. Journal of Human Nutrition and Dietetics vol. 18, (2) 99-116.
10.1111/j.1365-277X.2005.00593.x
Hu SP, Day NE, Li DR, Luben RN, Cai KL, Ou-Yang T, Li B, Lu XZ et al.(2005). Further evidence for an HLA-related recessive mutation in nasopharyngeal carcinoma among the Chinese. British Journal of Cancer vol. 92, (5) 967-970.
10.1038/sj.bjc.6602347
De Castro F, Moron FJ, Montoro L, Galan JJ, Real LM, Ruiz A, Dunning AM, Dowsett M et al.(2005). Re: Polymorphisms associated with circulating sex hormone levels in postmenopausal women (multiple letters) [2]. Journal of the National Cancer Institute vol. 97, (2) 152-154.
10.1093/jnci/dji029
Canoy D, Wareham N, Luben R, Welch A, Bingham S, Day N, Khaw KT(2005). Cigarette smoking and fat distribution in 21,828 british men and women: A population-based study. Obesity Research vol. 13, (8) 1466-1475.
10.1038/oby.2005.177
Sinha S, Luben RN, Welch A, Bingham S, Wareham NJ, Day NE, Khaw KT(2005). Fibrinogen and cigarette smoking in men and women in the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population. European Journal of Preventive Cardiology vol. 12, (2) 144-150.
10.1097/01.hjr.0000140719.09768.e2
Newhouse SJ, Huq SM, Arunachalam G, Caulfield MJ, Munroe PB(2005). Genetics of hypertension. Hypertension: Principles and Practice,
Low YL, Taylor JI, Grace PB, Dowsett M, Scollen S, Dunning AM, Mulligan AA, Welch AA et al.(2005). Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions. Cancer Epidemiology Biomarkers and Prevention vol. 14, (1) 213-220.
Low YL, Taylor JI, Grace PB, Dowsett M, Folkerd E, Doody D, Dunning AM, Scollen S et al.(2005). Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men. Journal of Nutrition vol. 135, (11) 2680-2686.
10.1093/jn/135.11.2680
Mein CA, Caulfield MJ, Munroe PB(2005). Selection of candidate genes in hypertension. vol. 108,
Jakes RW, Day NE, Luben R, Welch A, Bingham S, Mitchell J, Hennings S, Rennie K et al.(2004). Adjusting for energy intake - What measure to use in nutritional epidemiological studies?. International Journal of Epidemiology vol. 33, (6) 1382-1386.
10.1093/ije/dyh181
Day NE, Wong MY, Bingham S, Khaw KT, Luben R, Michels KB, Welch A, Wareham NJ(2004). Correlated measurement error - Implications for nutritional epidemiology. International Journal of Epidemiology vol. 33, (6) 1373-1381.
10.1093/ije/dyh138
Pattison DJ, Symmons DPM, Lunt M, Welch A, Luben R, Bingham SA, Khaw KT, Day NE et al.(2004). Dietary risk factors for the development of inflammatory polyarthritis: Evidence for a role of high level of red meat consumption. Arthritis and Rheumatism vol. 50, (12) 3804-3812.
10.1002/art.20731
Munroe PB, Dobson R, Pembroke J, Wilson S, Pheby J, Colville-Stewart S, Gilmour K, Macdade M et al. (2004). The MRC BRIGHT study: Demographic and biochemical characteristics of the sibling-pair resource. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 58, 688-688.
Lee YW, Oh VMS, Garcia E, Taylor EA, Wu HM, Yap EPH, Kazeem GR, Caulfield MJ et al.(2004). Haplotypes of the beta 2-adrenegic receptor gene are associated with essential hypertension in a Singaporean Chinese population. J HYPERTENS vol. 22, (11) 2111-2116.
10.1097/00004872-200411000-00012
Shohaimi S, Bingham S, Welch A, Luben R, Day N, Wareham N, Khaw KT(2004). Occupational social class, educational level and area deprivation independently predict plasma ascorbic acid concentration: Across-sectional population based study in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). European Journal of Clinical Nutrition vol. 58, (10) 1432-1435.
10.1038/sj.ejcn.1601979
DiCioccio RA, Song H, Waterfall C, Kimura MT, Nagase H, McGuire V, Hogdall E, Shah MN et al.(2004). STK15 polymorphisms and association with risk of invasive ovarian cancer. Cancer Epidemiology Biomarkers and Prevention vol. 13, (10) 1589-1594.
Freimer N, Sabatti C(2004). The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology. Nature Genetics vol. 36, (10) 1045-1051.
10.1038/ng1433
Khaw KT, Wareham N, Bingham S, Luben R, Welch A, Day N(2004). Association of hemoglobin A<inf>1c</inf> with cardiovascular disease and mortality in adults: The European prospective investigation into cancer in Norfolk. Annals of Internal Medicine vol. 141, (6)
10.7326/0003-4819-141-6-200409210-00006
Matthijs Boekholdt S, Peters RJG, Day NE, Luben R, Bingham SA, Wareham NJ, Hack CE, Reitsma PH et al.(2004). Macrophage migration inhibitory factor and the risk of myocardial infarction or death due to coronary artery disease in adults without prior myocardial infarction or stroke: The EPIC-Norfolk prospective population study. American Journal of Medicine vol. 117, (6) 390-397.
10.1016/j.amjmed.2004.04.010
Boekholdt SM, Kuivenhoven JA, Wareham NJ, Peters RJG, Jukema JW, Luben R, Bingham SA, Day NE et al.(2004). Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: The prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study. Circulation vol. 110, (11) 1418-1423.
10.1161/01.CIR.0000141730.65972.95
Burmana J, Trana CH, Glatt C, Freimer NB, Edwards RH(2004). The effect of rare human sequence variants on the function of vesicular monoamine transporter 2. Pharmacogenetics vol. 14, (9) 587-594.
10.1097/00008571-200409000-00003
Miettunen J, Kantojärvi L, Ekelund J, Veijola J, Karvonen JT, Peltonen L, Järvelin MR, Freimer N et al.(2004). A large population cohort provides normative data for investigation of temperament. Acta Psychiatrica Scandinavica vol. 110, (2) 150-157.
10.1111/j.1600-0047.2004.00344.x
Patel BD, Luben RN, Welch AA, Bingham SA, Khaw KT, Day NE, Lomas DA, Wareham NJ(2004). Childhood smoking is an independent risk factor for obstructive airways disease in women. Thorax vol. 59, (8) 682-686.
10.1136/thx.2003.010215
Boekholdt SM, Peters RJG, Hack CE, Day NE, Luben R, Bingham SA, Wareham NJ, Reitsma PH et al.(2004). IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: The EPIC-Norfolk prospective population study. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 24, (8) 1503-1508.
10.1161/01.ATV.0000134294.54422.2e
Shohaimi S, Welch A, Bingham S, Luben R, Day N, Wareham N, Khaw KT(2004). Residential area deprivation predicts fruit and vegetable consumption independently of individual educational level and occupational social class: A cross sectional population study in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). Journal of Epidemiology and Community Health vol. 58, (8) 686-691.
10.1136/jech.2003.008490
Mathews CA, Waller J, Glidden DV, Lowe TL, Herrera LD, Budman CL, Erenberg G, Naarden A et al.(2004). Self injurous behaviour in Tourette syndrome: Correlates with impulsivity and impulse control. Journal of Neurology, Neurosurgery and Psychiatry vol. 75, (8) 1149-1155.
10.1136/jnnp.2003.020693
Shohaimi S, Welch A, Bingham S, Luben R, Day N, Wareham N, Khaw KT(2004). Area deprivation predicts lung function independently of education and social class. European Respiratory Journal vol. 24, (1) 157-161.
10.1183/09031936.04.00088303
Klomp LWJ, Vargas JC, Van Mil SWC, Pawlikowska L, Strautnieks SS, Van Eijk MJT, Juijn JA, Pabón-Peña C et al.(2004). Characterization of mutations in ATP8B1 associated with hereditary cholestasis. Hepatology vol. 40, (1) 27-38.
10.1002/hep.20285
Michels KB, Bingham SA, Luben R, Welch AA, Day NE(2004). The effect of correlated measurement error in multivariate models of diet. American Journal of Epidemiology vol. 160, (1) 59-67.
10.1093/aje/kwh169
Pattison DJ, Silman AJ, Goodson NJ, Lunt M, Bunn D, Luben R, Welch A, Bingham S et al.(2004). Vitamin C and the risk of developing inflammatory polyarthritis: Prospective nested case-control study. Annals of the Rheumatic Diseases vol. 63, (7) 843-847.
10.1136/ard.2003.016097
Dunning AM, Dowsett M, Healey CS, Tee L, Luben RN, Folkerd E, Novik KL, Kelemen L et al.(2004). Polymorphisms associated with circulating sex hormone levels in postmenopausal women. Journal of the National Cancer Institute vol. 96, (12) 936-945.
10.1093/jnci/djh167
Canoy D, Luben R, Welch A, Bingham S, Wareham N, Day N, Khaw KT(2004). Abdominal obesity and respiratory function in men and women in the EPIC-Norfolk study, United Kingdom. American Journal of Epidemiology vol. 159, (12) 1140-1149.
10.1093/aje/kwh155
Rahman P, Jones A, Curtis J, Bartlett S, Peddle L, Fernandez BA, Freimer NB(2004). Erratum: The Newfoundland population: A unique resource for genetic investigation of complex diseases (Human Molecular Genetics (2003) vol. 12 (R167-R172)). Human Molecular Genetics vol. 13, (12)
10.1093/hmg/ddh143
Macleod J, Smith GD, Lynch J, Surtees P, Wainwright N, Luben R, Khaw KT, Day N(2004). Re: "Sense of coherence and mortality in men and women in the EPIC-Norfolk United Kingdom prospective cohort study" [2] (multiple letters). American Journal of Epidemiology vol. 159, (12) 1202-1204.
10.1093/aje/kwh157
Tjønneland AM, Overvad K, Bingham SA, Day NE, Luben R, Ferrari P, Slimani N, Norat T et al.(2004). Dietary fibers protect against colorectal cancer among the participants in the European Prospective Investigation into Cancer and Nutrition (EPiC) study. Ugeskrift for Laeger vol. 166, (25) 2458-2460.
Newhouse S, Dobson R, Wallace C, Pembroke J, Garcia E, Mein C, Clayton D, Samani N et al. (2004). No association of the WNK1 gene with essential hypertension in the MRC BRIGHT study. JOURNAL OF HYPERTENSION. vol. 22, S212-S212.
10.1097/00004872-200406002-00740
Khaw KT, Wareham N, Bingham S, Luben R, Welch A, Day N(2004). Preliminary communication: Glycated hemoglobin, diabetes, and incident colorectal cancer in men and women: A prospective analysis from the European Prospective Investigation into Cancer-Norfolk Study. Cancer Epidemiology Biomarkers and Prevention vol. 13, (6) 915-919.
Goodson NJ, Silman AJ, Pattison DJ, Lunt M, Bunn D, Luben R, Day N, Khaw KT et al.(2004). Traditional cardiovascular risk factors measured prior to the onset of inflammatory polyarthritis. Rheumatology vol. 43, (6) 731-736.
10.1093/rheumatology/keh161
Bearden CE, Reus VI, Freimer NB(2004). Why genetic investigation of psychiatric disorders is so difficult. Current Opinion in Genetics and Development vol. 14, (3) 280-286.
10.1016/j.gde.2004.04.005
Grace PB, Taylor JI, Low YL, Luben RN, Mulligan AA, Botting NP, Dowsett M, Welch AA et al.(2004). Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European Prospective Investigation of Cancer and Nutrition-Norfolk. Cancer Epidemiology Biomarkers and Prevention vol. 13, (5) 698-708.
Pawlikowska L, Groen A, Eppens EF, Kunne C, Ottenhoff R, Looije N, Knisely AS, Killeen NP et al.(2004). A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals pertubed bile salt homeostasis but no impairment in bile secretion. Human Molecular Genetics vol. 13, (8) 881-892.
10.1093/hmg/ddh100
Mein CA, Caulfield MJ, Dobson RJ, Munroe PB(2004). Genetics of essential hypertension. Human Molecular Genetics vol. 13, (REV. ISS. 1)
Mein CA, Caulfield MJ, Dobson RJ, Munroe PB(2004). Genetics of essential hypertension. Hum Mol Genet vol. 13 Spec No 1, R169-R175.
10.1093/hmg/ddh078
Mathews CA, Reus VI, Bejarano J, Escamilla MA, Fournier E, Herrera LD, Lowe TL, McInnes LA et al.(2004). Genetic studies of neuropsychiatric disorders in Costa Rica: A model for the use of isolated populations. Psychiatric Genetics vol. 14, (1) 13-23.
10.1097/00041444-200403000-00003
Hong KS, McInnes LA, Service SK, Song T, Lucas J, Silva S, Fournier E, León P et al.(2004). Genetic Mapping Using Haplotype and Model-Free Linkage Analysis Supports Previous Evidence for a Locus Predisposing to Severe Bipolar Disorder at 5q31-33. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 125 B, (1) 83-86.
10.1002/ajmg.b.20091
Yuyun MF, Khaw KT, Luben R, Welch A, Bingham S, Day NE, Wareham NJ(2004). A Prospective Study of Microalbuminuria and Incident Coronary Heart Disease and Its Prognostic Significance in a British Population: The EPIC-Norfolk Study. American Journal of Epidemiology vol. 159, (3) 284-293.
10.1093/aje/kwh037
Harding AH, Day NE, Khaw KT, Bingham SA, Luben RN, Welsh A, Wareham NJ(2004). Habitual fish consumption and glycated haemoglobin: The EPIC-Norfolk study. European Journal of Clinical Nutrition vol. 58, (2) 277-284.
10.1038/sj.ejcn.1601779
Yuyun MF, Khaw KT, Luben R, Welch A, Bingham S, Day NE, Wareham NJ(2004). Microalbuminuria and stroke in a British population: The European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. Journal of Internal Medicine vol. 255, (2) 247-256.
10.1046/j.1365-2796.2003.01264.x
Yuyun MF, Khaw KT, Luben R, Welch A, Bingham S, Day NE, Wareham NJ(2004). Microalbuminuria independently predicts all-cause and cardiovascular mortality in a British population: The European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. International Journal of Epidemiology vol. 33, (1) 189-198.
10.1093/ije/dyh008
Khaw KT, Reeve J, Luben R, Bingham S, Welch A, Wareham N, Oakes S, Day N(2004). Prediction of total and hip fracture risk in men and women by quantitative ultrasound of the calcaneus: EPIC-Norfolk prospective population study. Lancet vol. 363, (9404) 197-202.
10.1016/S0140-6736(03)15325-1
Mehan MR, Freimer NB, Ophoff RA(2004). A genome-wide survey of segmental duplications that mediate common human genetic variation of chromosomal architecture. Human genomics vol. 1, (5) 335-344.
10.1186/1479-7364-1-5-335
Khaw KT, Bingham S, Welch A, Luben R, O'Brien E, Wareham N, Day N(2004). Blood pressure and urinary sodium in men and women: the Norfolk Cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). The American journal of clinical nutrition vol. 80, (5) 1397-1403.
10.1093/ajcn/80.5.1397
Harding AH, Day NE, Khaw KT, Bingham S, Luben R, Welsh A, Wareham NJ(2004). Dietary Fat and the Risk of Clinical Type 2 Diabetes: The European Prospective Investigation of Cancer-Norfolk Study. American Journal of Epidemiology vol. 159, (1) 73-82.
10.1093/aje/kwh004
Canoy D, Luben R, Welch A, Bingham S, Wareham N, Day N, Khaw KT(2004). Fat distribution, body mass index and blood pressure in 22 090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. Journal of Hypertension vol. 22, (11) 2067-2074.
10.1097/00004872-200411000-00007
Yuyun MF, Khaw KT, Luben R, Welch A, Bingham S, Day NE, Wareham NJ(2004). Microalbuminuria, cardiovascular risk factors and cardiovascular morbidity in a British population: The EPIC-Norfolk Population-based Study. European Journal of Cardiovascular Prevention and Rehabilitation vol. 11, (3) 207-213.
10.1097/01.hjr.0000133070.75016.1d
Glatt CE, Tampilic M, Christie C, DeYoung J, Freimer NB(2004). Re-Screening Serotonin Receptors for Genetic Variants Identifies Population and Molecular Genetic Complexity. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 124 B, (1) 92-100.
10.1002/ajmg.b.20056
Surtees P, Wainwright N, Luben R, Khaw KT, Day N(2003). Sense of Coherence and Mortality in Men and Women in the EPIC-Norfolk United Kingdom Prospective Cohort Study. American Journal of Epidemiology vol. 158, (12) 1202-1209.
10.1093/aje/kwg272
Rahman P, Jones A, Curtis J, Bartlett S, Peddle L, Fernandez BA, Freimer NB(2003). The Newfoundland population: A unique resource for genetic investigation of complex diseases. Human Molecular Genetics vol. 12, (REV. ISS. 2)
10.1093/hmg/ddg257
Surtees P, Wainwright N, Khaw KT, Luben R, Brayne C, Day N(2003). Inflammatory dispositions: A population-based study of the association between hostility and peripheral leukocyte counts. Personality and Individual Differences vol. 35, (6) 1271-1284.
10.1016/S0191-8869(02)00347-1
Bingham SA, Day NE, Luben R(2003). Erratum: Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): An observational study (Lancet (2003) 361 (1496-1501)). Lancet vol. 362, (9388)
10.1016/S0140-6736(03)14387-5
Jakes RW, Day NE, Khaw KT, Luben R, Oakes S, Welch A, Bingham S, Wareham NJ(2003). Television viewing and low participation in vigorous recreation are independently associated with obesity and markers of cardiovascular disease risk: EPIC-Norfolk population-based study. European Journal of Clinical Nutrition vol. 57, (9) 1089-1096.
10.1038/sj.ejcn.1601648
Newhouse SJ, Garcia E, Caulfield M, Munroe P (2003). Haplotype structure of the WNK1 gene and association studies in hypertensive populations. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 56, 245-245.
Bingham SA, Luben R, Welch A, Wareham N, Khaw KT, Day N(2003). Are imprecise methods obscuring a relation between fat and breast cancer?. Lancet vol. 362, (9379) 212-214.
10.1016/S0140-6736(03)13913-X
Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI, Craddock N, DePaulo JR et al.(2003). Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. American Journal of Human Genetics vol. 73, (1) 49-62.
10.1086/376547
Munroe PB, Editorial Board(2003). Hypercholesterolaemia and vascular function: is the p22phox gene the missing link?. Clin Sci (Lond) vol. 105, (1) 11-12.
10.1042/CS20030106
Caulfield M, Munroe P, Pembroke J, Samani N, Dominiczak A, Brown M, Benjamin N, Webster J et al.(2003). Genome-wide mapping of human loci for essential hypertension. Lancet vol. 361, (9375) 2118-2123.
10.1016/S0140-6736(03)13722-1
Sabatti C, Service S, Freimer N(2003). False discovery rate in linkage and association genome screens for complex disorders. Genetics vol. 164, (2) 829-833.
Dunning AM, Ellis PD, McBride S, Kirschenlohr HL, Healey CS, Kemp PR, Luben RN, Chang-Claude J et al.(2003). A transforming growth factorβ1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer. Cancer Research vol. 63, (10) 2610-2615.
Bingham SA, Day NE, Luben R, Ferrari P, Slimani N, Norat T, Clavel-Chapelon F, Kesse E et al.(2003). Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): An observational study. Lancet vol. 361, (9368) 1496-1501.
10.1016/S0140-6736(03)13174-1
Service SK, Sandkuijl LA, Freimer NB(2003). Cost-effective designs for linkage disequilibrium mapping of complex traits. American Journal of Human Genetics vol. 72, (5) 1213-1220.
10.1086/375165
Carvajal-Carmona LG, Ophoff R, Service S, Hartiala J, Molina J, Leon P, Ospina J, Bedoya G et al.(2003). Genetic demography of Antioquia (Colombia) and the Central Valley of Costa Rica. Human Genetics vol. 112, (5-6) 534-541.
10.1007/s00439-002-0899-8
Freimer N, Sabatti C(2003). The human phenome project. Nature Genetics vol. 34, (1) 15-21.
10.1038/ng0503-15
Surtees P, Wainwright N, Day N, Luben R, Brayne C, Khaw KT(2003). Association of depression with peripheral leukocyte counts in EPIC-Norfolk - Role of sex and cigarette smoking. Journal of Psychosomatic Research vol. 54, (4) 303-306.
10.1016/S0022-3999(02)00456-7
Shohaimi S, Luben R, Wareham N, Day N, Bingham S, Welch A, Oakes S, Khaw KT(2003). Residential area deprivation predicts smoking habit independently of individual educational level and occupational social class. A cross sectional study in the Norfolk cohort of the European Investigation into Cancer (EPIC-Norfolk). Journal of Epidemiology and Community Health vol. 57, (4) 270-276.
10.1136/jech.57.4.270
Knight J, Munroe PB, Pembroke JC, Caulfield MJ(2003). Human chromosome 17 in essential hypertension. Ann Hum Genet vol. 67, (Pt 2) 193-206.
10.1046/j.1469-1809.2003.t01-1-00002.x
Surtees P, Wainwright N, Day N, Brayne C, Luben R, Khaw KT(2003). Adverse experience in childhood as a developmental risk factor for altered immune status in adulthood. International Journal of Behavioral Medicine vol. 10, (3) 251-268.
10.1207/S15327558IJBM1003_05
Garcia EA, Newhouse S, Caulfield MJ, Munroe PB(2003). Genes and hypertension. Curr Pharm Des vol. 9, (21) 1679-1689.
10.2174/1381612033454513
Smith MR, Kinmonth AL, Luben RN, Bingham S, Day NE, Wareham NJ, Welch A, Khaw KT(2003). Smoking status and differential white cell count in men and women in the EPIC-Norfolk population. Atherosclerosis vol. 169, (2) 331-337.
10.1016/S0021-9150(03)00200-4
Sieri S, Agudo A, Kesse E, Klipstein-Grobusch K, San-José B, Welch AA, Krogh V, Luben R et al.(2002). Patterns of alcohol consumption in 10 European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) project. Public Health Nutrition vol. 5, (6 B) 1287-1296.
10.1079/PHN2002405
Welch AA, Lund E, Amiano P, Dorronsoro M, Brustad M, Kumle M, Rodriguez M, Lasheras C et al.(2002). Variability of fish consumption within the 10 European countries participating in the European Investigation into Cancer and Nutrition (EPIC) study. Public Health Nutrition vol. 5, (6 B) 1273-1285.
10.1079/PHN2002404
Garcia EA, Aristizabal D, McEwen J, Mendez J, Munroe P, Caulfield M (2002). Guanine nucleotide binding 3 (GNB3) haplotype analysis in the Venecia-Colombia Latin-American blood pressure study. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 71, 366-366.
Merikangas KR, Chakravarti A, Moldin SO, Araj H, Blangero J, Burmeister M, Crabbe JC, Depaulo JR et al.(2002). Future of genetics of mood disorders research. Biological Psychiatry vol. 52, (6) 457-477.
10.1016/S0006-3223(02)01471-3
Sandhu MS, Luben R, Day NE, Khaw KT(2002). Self-reported birth weight and subsequent risk of colorectal cancer. Cancer Epidemiology Biomarkers and Prevention vol. 11, (9) 935-938.
Escamilla MA, Batki S, Reus VI, Spesny M, Molina J, Service S, Vinogradov S, Neylan T et al.(2002). Comorbidity of bipolar disorder and substance abuse in Costa Rica: Pedigree- and population-based studies. Journal of Affective Disorders vol. 71, (1-3) 71-83.
10.1016/S0165-0327(01)00373-1
Jakes RW, Day NE, Patel B, Khaw KT, Oakes S, Luben R, Welch A, Bingham S et al.(2002). Physical inactivity is associated with lower forced expiratory volume in 1 second: European prospective investigation into cancer-norfolk prospective population study. American Journal of Epidemiology vol. 156, (2) 139-147.
10.1093/aje/kwf021
Glatt CE, Freimer NB(2002). Association analysis of candidate genes for neuropsychiatric disease: The perpetual campaign. Trends in Genetics vol. 18, (6) 307-312.
10.1016/S0168-9525(02)02670-7
Caulfield M, Pembroke J, Dominiczak A, Samani N, Brown M, Clayton D, Ratcliffe P, Lathrop M et al. (2002). The MRC British Genetics of Hypertension Study - Genome-wide screen results. JOURNAL OF HYPERTENSION. vol. 20, S7-S7.
Harding AH, Sargeant LA, Khaw KT, Welch A, Oakes S, Luben RN, Bingham S, Day NE et al.(2002). Cross-sectional association between total level and type of alcohol consumption and glycosylated haemoglobin level: The epic-norfolk study. European Journal of Clinical Nutrition vol. 56, (9) 882-890.
10.1038/sj.ejcn.1601408
Mulligan AA, Luben RN, Welch AA, Bingham SA(2002). Daidzein and genistein intakes in England (the EPIC Norfolk cohort). IARC scientific publications vol. 156, 369-370.
Ophoff RA, Escamilla MA, Service SK, Spesny M, Meshi DB, Poon W, Molina J, Fournier E et al.(2002). Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate. American Journal of Human Genetics vol. 71, (3) 565-574.
10.1086/342291
Bingham SA, Luben R, Day NE, Riboli E, EPIC Working Group on Dietary Patterns(2002). Plant polysaccharides, meat and colorectal cancer. IARC scientific publications vol. 156, 349-352.
Luben R, Khaw KT, Welch A, Bingham S, Wareham N, Oakes S, Day NE(2002). Plasma vitamin C, cancer mortality and incidence in men and women: a prospective study. IARC scientific publications vol. 156, 117-118.
Couto E, Harrison DAH, Duffy SW, Myles J, Sala E, Warren RML, Day NE, Luben R et al.(2001). Estimation of disease progression parameters from case-control data: Application to mammographic patterns and breast cancer natural history. Journal of Epidemiology and Biostatistics vol. 6, (2) 235-242.
10.1080/135952201753173015
Titan SMO, Bingham S, Welch A, Luben R, Oakes S, Day N, Khaw KT(2001). Frequency of eating and concentrations of serum cholesterol in the Norfolk population of the European prospective investigation into cancer (EPIC-Norfolk): Cross sectional study. British Medical Journal vol. 323, (7324) 1286-1288.
10.1136/bmj.323.7324.1286
Sandhu MS, Luben R, Khaw KT(2001). Self reported non-insulin dependent diabetes, family history, and risk of prevalent colorectal cancer: Population based, cross sectional study. Journal of Epidemiology and Community Health vol. 55, (11) 804-805.
10.1136/jech.55.11.804
McInnes LA, Service SK, Reus VI, Barnes G, Charlat O, Jawahar S, Lewitzky S, Yang Q et al.(2001). Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population. Proceedings of the National Academy of Sciences of the United States of America vol. 98, (20) 11485-11490.
10.1073/pnas.191519098
Metherell LA, Akker SA, Munroe PB, Rose SJ, Caulfield M, Savage MO, Chew SL, Clark AJ(2001). Pseudoexon activation as a novel mechanism for disease resulting in atypical growth-hormone insensitivity. Am J Hum Genet vol. 69, (3) 641-646.
10.1086/323266
McKeown NM, Day NE, Welch AA, Runswick SA, Luben RN, Mulligan AA, McTaggart A, Bingham SA(2001). Use of biological markers to validate self-reported dietary intake in a random sample of the European Prospective Investigation into Cancer United Kingdom Norfolk cohort. American Journal of Clinical Nutrition vol. 74, (2) 188-196.
10.1093/ajcn/74.2.188
Sala E, Warren R, McCann J, Duffy S, Luben R, Day N(2001). Mammographic parenchymal patterns and breast cancer natural history: A case-control study. Acta Oncologica vol. 40, (4) 461-465.
10.1080/028418601750288172
Faham M, Baharloo S, Tomitaka S, Deyoung J, Freimer NB(2001). Mismatch repair detection (MRD): High-throughput scanning for DNA variations. Human Molecular Genetics vol. 10, (16) 1657-1664.
10.1093/hmg/10.16.1657
Sandhu MS, Luben R, Khaw KT(2001). Prevalence and family history of colorectal cancer: Implications for screening. Journal of Medical Screening vol. 8, (2) 69-72.
10.1136/jms.8.2.69
Sargeant LA, Khaw KT, Bingham S, Day NE, Luben RN, Oakes S, Welch A, Wareham NJ(2001). Fruit and vegetable intake and population glycosylated haemoglobin levels: The EPIC-Norfolk study. European Journal of Clinical Nutrition vol. 55, (5) 342-348.
10.1038/sj.ejcn.1601162
Leung KY, Greene ND, Munroe PB, Mole SE(2001). Identification of a transactivation motif in the CLN3 protein. IUBMB Life vol. 51, (5) 295-298.
10.1080/152165401317190798
Glatt CE, DeYoung JA, Delgado S, Service SK, Giacomini KM, Edwards RH, Risch N, Freimer NB(2001). Screening a large reference sample to identify very low frequency sequence variants: Comparisons between two genes. Nature Genetics vol. 27, (4) 435-438.
10.1038/86948
Escamilla MA, McInnes LA, Service SK, Spesny M, Reus VI, Molina J, Gallegos A, Fournier E et al.(2001). Genome screening for linkage disequilibrium in a costa rican sample of patients with bipolar-I disorder: A follow-up study on chromosome 18. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 105, (2) 207-213.
10.1002/ajmg.1205
Khaw KT, Bingham S, Welch A, Luben R, Wareham N, Oakes S, Day N(2001). Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: A prospective population study. Lancet vol. 357, (9257) 657-663.
10.1016/S0140-6736(00)04128-3
Service SK, Ophoff RA, Freimer NB(2001). The genome-wide distribution of background linkage disequilibrium in a population isolate. Human Molecular Genetics vol. 10, (5) 545-551.
10.1093/hmg/10.5.545
Jakes RW, Khaw KT, Day NE, Bingham S, Welch A, Oakes S, Luben R, Dalzell N et al.(2001). Patterns of physical activity and ultrasound attenuation by heel bone among Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): Population based study. British Medical Journal vol. 322, (7279) 140-143.
10.1136/bmj.322.7279.140
Khaw KT, Wareham N, Luben R, Bingham S, Oakes S, Welch A, Day N(2001). Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of European Prospective Investigation of Cancer and Nutrition (EPIC-Norfolk). BMJ vol. 322, (7277)
10.1136/bmj.322.7277.15
Leung KY, Greene ND, Munroe PB, Mole SE(2001). Analysis of CLN3-protein interactions using the yeast two-hybrid system. Eur J Paediatr Neurol vol. 5 Suppl A, 89-93.
10.1053/ejpn.2000.0441
Sargeant LA, Khaw KT, Bingham S, Day NE, Luben RN, Oakes S, Welch A, Wareham NJ(2001). Cigarette smoking and glycaemia: The EPIC-Norfolk study. International Journal of Epidemiology vol. 30, (3) 547-554.
10.1093/ije/30.3.547
Mathews CA, Herrera Amighetti LD, Lowe TL, Van De Wetering BJM, Freimer NB, Reus VI(2001). Cultural influences on diagnosis and perception of Tourette syndrome in Costa Rica. Journal of the American Academy of Child and Adolescent Psychiatry vol. 40, (4) 456-463.
10.1097/00004583-200104000-00015
Welch AA, McTaggart A, Mulligan AA, Luben R, Walker N, Khaw KT, Day NE, Bingham SA(2001). DINER (Data Into Nutrients for Epidemiological Research) - A new data-entry program for nutritional analysis in the EPIC-Norfolk cohort and the 7-day diary method. Public Health Nutrition vol. 4, (6) 1253-1265.
10.1079/PHN2001196
Harding AH, Sargeant LA, Welch A, Oakes S, Luben RN, Bingham S, Day NE, Khaw KT et al.(2001). Fat consumption and HbA<inf>1c</inf> levels: The EPIC-norfolk study. Diabetes Care vol. 24, (11) 1911-1916.
10.2337/diacare.24.11.1911
Ophoff RA, De Young J, Service SK, Joosse M, Caffo NA, Sandkuijl LA, Terwindt GM, Haan J et al.(2001). Hereditary vascular retinopathy, cerebroretinal vasculopathy, and hereditary endotheliopathy with retinopathy, nephropathy, and stroke map to a single locus on chromosome 3p21.1-p21.3. American Journal of Human Genetics vol. 69, (2) 447-453.
10.1086/321975
Garner C, McInnes LA, Service SK, Spesny M, Fournier E, Leon P, Freimer NB(2001). Linkage analysis of a complex pedigree with severe bipolar disorder, using a Markov chain Monte Carlo method. American Journal of Human Genetics vol. 68, (4) 1061-1064.
10.1086/319517
Bingham SA, Welch AA, McTaggart A, Mulligan AA, Runswick SA, Luben R, Oakes S, Khaw KT et al.(2001). Nutritional methods in the European prospective investigation of cancer in Norfolk. Public Health Nutrition vol. 4, (3) 847-858.
10.1079/phn2000102
Basham VM, Pharoah PDP, Healey CS, Luben RN, Day NE, Easton DF, Ponder BAJ, Dunning AM(2001). Polymorphisms in CYP1A1 and smoking: No association with breast cancer risk. Carcinogenesis vol. 22, (11) 1797-1800.
10.1093/carcin/22.11.1797
Munroe PB, Knight J, Caulfield MJ(2000). 1990-2000: Progress in determining high blood pressure genes. Annals of the Academy of Medicine Singapore vol. 29, (3) 357-363.
Sala E, Warren R, McCann J, Duffy S, Luben R, Day N(2000). Smoking and high-risk mammographic parenchymal patterns: A case-control study. Breast Cancer Research vol. 2, (1) 59-63.
10.1186/bcr29
Healey CS, Dunning AM, Dawn Teare M, Chase D, Parker L, Burn J, Chang-Claude J, Mannermaa A et al.(2000). A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability. Nature Genetics vol. 26, (3) 362-364.
10.1038/81691
Ospina-Duque J, Duque C, Carvajal-Carmona L, Ortiz-Barrientos D, Soto I, Pineda N, Cuartas M, Calle J et al.(2000). An association study of bipolar mood disorder (type I) with the 5-HTTLPR serotonin transporter polymorphism in a human population isolate from Colombia. Neuroscience Letters vol. 292, (3) 199-202.
10.1016/S0304-3940(00)01464-6
Eksandh L, Ponjavic V, Munroe PB, Eiberg H, Uvebrant P, Ehinger B, Mole SE, Andréasson S(2000). Full-field ERG in patients with Batten/Spielmeyer-Vogt disease caused by mutations in the CLN3 gene. Ophthalmic Genetics vol. 21, (2) 69-77.
10.1076/1381-6810(200006)2121-8ft069
Ospina-Duque J, Carvajal-Carmona L, Calle J, López C, Ochoa L, García J, Cuartas M, Ortiz-Barrientos D et al.(2000). A search for genetic loci involved in predisposition to bipolar mood disorder in the population of Antioquia, Colombia. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 96, (4)
Ospina-Duque J, Duque C, Carvajal-Carmona L, Cuartas M, Ortiz-Barrientos D, Soto I, Pineda N, Calle J et al.(2000). Lack of association between a serotonin transporter promoter polymorphism and BP1 in Antioquia, Colombia. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 96, (4) 490-491.
Munroe PB, Caulfield MJ(2000). Genetics of hypertension. Current Opinion in Genetics and Development vol. 10, (3) 325-329.
10.1016/S0959-437X(00)00081-2
Escamilla M, DeMille MC, Benavides E, Roche E, Almasy L, Pittman S, Hauser J, Lew DF et al.(2000). A minimalist approach to gene mapping: Locating the gene for acheiropodia, by homozygosity analysis. American Journal of Human Genetics vol. 66, (6) 1995-2000.
10.1086/302921
Caulfield M, Papp J, Pembroke J, Munroe P, Farrall M, Dominiczak A, Clayton D, Ratcliffe P et al. (2000). A new tool for checks of data precision within the MRC British genetics of hypertension study. J HYPERTENS. vol. 18, S180-S180.
Baharloo S, Service SK, Risch N, Gitschier J, Freimer NB(2000). Familial aggregation of absolute pitch. American Journal of Human Genetics vol. 67, (3) 755-758.
10.1086/303057
Sala E, Warren R, Duffy S, Welch A, Luben R, Day N(2000). High risk mammographic parenchymal patterns and diet: A case-control study. British Journal of Cancer vol. 83, (1) 121-126.
10.1054/bjoc.2000.1151
Sala E, Warren R, McCann J, Duffy S, Luben R, Day N(2000). High-risk mammographic parenchymal patterns, hormone replacement therapy and other risk factors: A case-control study. International Journal of Epidemiology vol. 29, (4) 629-636.
10.1093/ije/29.4.629
Alsanea O, Wada N, Ain K, Wong M, Taylor K, Ituarte PHG, Treseler PA, Weier HU et al.(2000). Is familial non-medullary thyroid carcinoma more aggressive than sporadic thyroid cancer? A multicenter series. Surgery vol. 128, (6) 1043-1051.
10.1067/msy.2000.110848
Bull LN, Roche E, Song EJ, Pedersen J, Knisely AS, Van der Hagen CB, Eiklid K, Aagenaes Ø et al.(2000). Mapping of the locus for cholestasis-lymphedema syndrome (aagenaes syndrome) to a 6.6-cM interval on chromosome 15q. American Journal of Human Genetics vol. 67, (4) 994-999.
10.1086/303080
Munroe P, Sandhu M, Jadhav D, Knight J, Clark A, Caulfield M(2000). No association of the epithelial sodium channel beta-subunit T594M variant with essential hypertension in an African Caribbean population. J HYPERTENS vol. 18, S178-S178.
Healey CS, Dunning AM, Durocher F, Teare D, Pharoah PDP, Luben RN, Easton DF, Ponder BAJ(2000). Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk. Carcinogenesis vol. 21, (2) 189-193.
10.1093/carcin/21.2.189
Sala E, Solomon L, Warren R, McCann J, Duffy S, Luben R, Day N(2000). Size, node status and grade of breast tumours: Association with mammographic parenchymal patterns. European Radiology vol. 10, (1) 157-161.
10.1007/s003300050025
Fraser GE, Welch A, Luben R, Bingham SA, Day NE(2000). The effect of age, sex, and education on food consumption of a middle- aged English cohort - EPIC in East Anglia. Preventive Medicine vol. 30, (1) 26-34.
10.1006/pmed.1999.0598
Dunning AM, Durocher F, Healey CS, Teare MD, McBride SE, Carlomagno F, Xu CF, Dawson E et al.(2000). The extent of linkage disequilibrium in four populations with distinct demographic histories. American Journal of Human Genetics vol. 67, (6) 1544-1554.
10.1086/316906
Sargeant LA, Wareham NJ, Bingham S, Day NE, Luben RN, Oakes S, Welch A, Khaw KT(2000). Vitamin C and hyperglycemia in the European Prospective Investigation Into Cancer - Norfolk (EPIC-Norfolk) study. Diabetes Care vol. 23, (6) 726-732.
10.2337/diacare.23.6.726
Dunning AM, McBride S, Gregory J, Durocher F, Foster NA, Healey CS, Smith N, Pharoah PDP et al.(1999). No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer. Carcinogenesis vol. 20, (11) 2131-2135.
10.1093/carcin/20.11.2131
Mole SE, Mitchison HM, Munroe PB(1999). Molecular basis of the neuronal ceroid lipofuscinoses: Mutations in CLN1, CLN2, CLN3, and CLN5. Human Mutation vol. 14, (3) 199-215.
10.1002/(SICI)1098-1004(1999)14:3<199::AID-HUMU3>3.0.CO;2-A
Bull LN, Pabón-Peña CR, Freimer NB(1999). Compound microsatellite repeats: Practical and theoretical features. Genome Research vol. 9, (9) 830-838.
10.1101/gr.9.9.830
Day N, Oakes S, Luben R, Khaw KT, Bingham S, Welch A, Wareham N (1999). EPIC-Norfolk: Study design and characteristics of the cohort. British Journal of Cancer. vol. 80, 95-103.
Lauronen L, Munroe PB, Järvelä I, Autti T, Mitchison HM, O'Rawe AM, Gardiner RM, Mole SE et al.(1999). Delayed classic and protracted phenotypes of compound heterozygous juvenile neuronal ceroid lipofuscinosis. Neurology vol. 52, (2) 360-365.
10.1212/wnl.52.2.360
Escamilla MA, McInnes LA, Spesny M, Reus VI, Service SK, Shimayoshi N, Tyler DJ, Silva S et al.(1999). Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: An initial screen for bipolar disorder loci on chromosome 18. American Journal of Human Genetics vol. 64, (6) 1670-1678.
10.1086/302400
Bull LN, Juijn JA, Liao M, Van Eijk MJT, Sinke RJ, Stricker NL, DeYoung JA, Carlton VEH et al.(1999). Erratum: Fine-resolution mapping by haplotype evaluation: The examples of PFIC1 and BRIC (Human Genetics (1999) 104 (241-248)). Human Genetics vol. 104, (6)
10.1007/s004390051000
Bull LN, Juijn JA, Liao M, Van Eijk MJT, Sinke RJ, Stricker NL, DeYoung JA, Carlton VEH et al.(1999). Fine-resolution mapping by haplotype evaluation: The examples of PFIC1 and BRIC. Human Genetics vol. 104, (3) 241-248.
10.1007/PL00008714
Sala E, Warren R, McCann J, Duffy S, Luben R, Day N(1999). High risk mammographic parenchymal patterns and anthropometric measures: A case-control study. British Journal of Cancer vol. 81, (7) 1257-1261.
10.1038/sj.bjc.6690838
Service SK, Lang DWT, Freimer NB, Sandkuijl LA(1999). Linkage-disequilibrium mapping of disease genes by reconstruction of ancestral haplotypes in founder populations. American Journal of Human Genetics vol. 64, (6) 1728-1738.
10.1086/302398
Munroe PB, Olgunturk RO, Fryns JP, Van Maldergem L, Ziereisen F, Yuksel B, Gardiner RM, Chung E(1999). Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome. Nature Genetics vol. 21, (1) 142-144.
10.1038/5102
Stephenson JBP, Greene NDE, Leung KY, Munroe PB, Mole SE, Gardiner RM, Taschner PEM, O'Regan M et al. (1999). The molecular basis of GROD-storing neuronal ceroid lipofuscinoses in Scotland. Molecular Genetics and Metabolism. vol. 66, 245-247.
10.1006/mgme.1999.2831
Strautnieks SS, Bull LN, Knisely AS, Kocoshis SA, Dahl N, Arnell H, Sokal E, Dahan K et al.(1998). A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nature Genetics vol. 20, (3) 233-238.
10.1038/3034
Munroe PB, Greene NDE, Leung KY, Mole SE, Gardiner RM, Mitchison HM, Stephenson JBP, Crow YJ(1998). Sharing of PPT mutations between distinct clinical forms of neuronal ceroid lipofuscinoses in patients from Scotland [4]. Journal of Medical Genetics vol. 35, (9)
10.1136/jmg.35.9.790
Munroe PB, Strautnieks SS, Farrall M, Daniel HI, Lawson M, DeFreitas P, Fogarty P, Gardiner RM et al.(1998). Absence of linkage of the epithelial sodium channel to hypertension in black Caribbeans. American Journal of Hypertension vol. 11, (8 I) 942-945.
10.1016/S0895-7061(98)00092-2
Knowles JA, Fyer AJ, Vieland VJ, Weissman MM, Hodge SE, Heiman GA, Haghighi F, De Jesus GM et al.(1998). Results of a genome-wide genetic screen for panic disorder. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 81, (2) 139-147.
10.1002/(SICI)1096-8628(19980328)81:2<139::AID-AJMG4>3.0.CO;2-R
Bull LN, Van Eijk MJT, Pawlikowska L, DeYoung JA, Juijn JA, Liao M, Klomp LWJ, Lomri N et al.(1998). A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis. Nature Genetics vol. 18, (3) 219-224.
10.1038/ng0398-219
Mitchison HM, Hofmann SL, Becerra CHR, Munroe PB, Lake BD, Crow YJ, Stephenson JBP, Williams RE et al.(1998). Mutations in the palmitoyl-protein thioesterase gene (PPT; CLN1) causing juvenile neuronal ceroid lipofuscinosis with granular osmiophilic deposits. Human Molecular Genetics vol. 7, (2) 291-297.
10.1093/hmg/7.2.291
Baharloo S, Johnston PA, Service SK, Gitschier J, Freimer NB(1998). Absolute pitch: An approach for identification of genetic and nongenetic components. American Journal of Human Genetics vol. 62, (2) 224-231.
10.1086/301704
Wolkoff AW, Suchy FJ, Moseley RH, Meier PJ, Gollan JL, Freimer N, Fitz JG, Boyer JL et al. (1998). Advances in hepatic transport: Molecular mechanisms, genetic disorders, and treatment. A summary of the 1998 AASLD single topic conference. Hepatology. vol. 28, 1713-1719.
10.1002/hep.510280637
Mitchison HM, Hofmann SL, Becerra CHR, Munroe PB, Lake BD, Crow YJ, Stephenson JBP, Williams RE et al.(1998). Corrigendum: Mutations in the palmitoyl-protein thioesterase gene (PPT; CLN1) causing juvenile neuronal ceroid lipofuscinosis with granular osmiophilic deposits (Human Molecular Genetics (1998) 7 (291-297)). Human Molecular Genetics vol. 7, (4)
Knisely AS, Freimer NB(1998). Insight into bile duct differentiation takes (notched) wings. Hepatology (Baltimore, Md.) vol. 27, (1) 298-299.
10.1002/hep.510270145
Sala E, Warren R, McCann J, Duffy S, Day N, Luben R(1998). Mammographic parenchymal patterns and mode of detection: Implications for the breast screening programme. Journal of Medical Screening vol. 5, (4) 207-212.
10.1136/jms.5.4.207
McInnes LA, Reus VI, Freimer NB(1998). Mapping genes for psychiatric disorders and behavioral traits. Current Opinion in Genetics and Development vol. 8, (3) 287-292.
10.1016/S0959-437X(98)80083-X
Bull LN, Freimer NB, Balistreri WF, O'Connell N, Setchell KDR, Kocoshis SA, Putnam PE, Agostini RM et al.(1997). A non-Amish infant with true Byler disease. Pediatric Pathology and Laboratory Medicine vol. 17, (3) 522-523.
Sinke RJ, Carlton VEH, Juijn JA, Delhaas T, Bull L, Van Berge Henegouwen GP, Van Hattum J, Keller KM et al.(1997). Benign recurrent intrahepatic cholestasis (BRIC): Evidence of genetic heterogeneity and delimitation of the BRIC locus to a 7-cM interval between D18S69 and D18S64. Human Genetics vol. 100, (3-4) 382-387.
10.1007/s004390050520
Mitchison HM, Munroe PB, O'Rawe AM, Taschner PEM, De Vos N, Kremmidiotis G, Lensink I, Munk AC et al.(1997). Genomic structure and complete nucleotide sequence of the Batten disease gene, CLN3. Genomics vol. 40, (2) 346-350.
10.1006/geno.1996.4576
Freimer NB, Service SK, Slatkin M(1997). Expanding on population studies. Nature Genetics vol. 17, (4) 371-373.
10.1038/ng1297-371
Bull LN, Carlton VEH, Stricker NL, Baharloo S, DeYoung JA, Freimer NB, Magid MS, Kahn E et al.(1997). Genetic and morphological findings in progressive familial intrahepatic cholestasis (Byler disease [PFIC-1] and Byler syndrome): Evidence for heterogeneity. Hepatology vol. 26, (1) 155-164.
10.1002/hep.510260121
Strautnieks SS, Kagalwalla AF, Tanner MS, Knisely AS, Bull L, Freimer N, Kocoshis SA, Gardiner RM et al.(1997). Identification of a locus for progressive familial intrahepatic cholestasis PFIC2 on chromosome 2q24. American Journal of Human Genetics vol. 61, (3) 630-633.
10.1086/515501
Caulfield M, Bouloux PM, Munroe P (1997). Progress in determining the genes for hypertension, insulin resistance, and dyslipidemia. Annals of the New York Academy of Sciences. vol. 827, 110-117.
10.1111/j.1749-6632.1997.tb51826.x
Munroe PB, Mitchison HM, O'Rawe AM, Anderson JW, Boustany RM, Lerner TJ, Taschner PEM, De Vos N et al.(1997). Spectrum of mutations in the Batten disease gene, CLN3. American Journal of Human Genetics vol. 61, (2) 310-316.
10.1086/514846
Munroe PB, O'Rawe AM, Mitchison HM, Järvelä IE, Santavuori P, Lerner TJ, Taschner PEM, Gardiner RM et al.(1997). Strategy for mutation detection in CLN3: Characterisation of two Finnish mutations. Neuropediatrics vol. 28, (1) 15-17.
10.1055/s-2007-973657
Mitchison HM, Taschner PEM, Kremmidiotis C, Callen DF, Doggett NA, Lerner TJ, Janes RB, Wallace BA et al.(1997). Structure of the CLN3 gene and predicted structure, location and function of CLN3 protein. Neuropediatrics vol. 28, (1) 12-14.
10.1055/s-2007-973656
Daniel HI, Munroe PB, Kamdar SM, Lawson M, Lavender P, Forgaty P, Caulfield MJ(1997). The atrial natriuretic peptide gene and essential hypertension in African-Caribbeans from St Vincent and the Grenadines. Journal of Human Hypertension vol. 11, (2) 113-117.
10.1038/sj.jhh.1000389
Reus VI, Freimer NB(1997). Understanding the genetic basis of mood disorders: Where do we stand?. American Journal of Human Genetics vol. 60, (6) 1283-1288.
10.1086/515482
Janes RW, Munroe PB, Mitchison HM, Gardiner RM, Mole SE, Wallace BA(1996). A model for Batten disease protein CLN3: Functional implications from homology and mutations. FEBS Letters vol. 399, (1-2) 75-77.
10.1016/S0014-5793(96)01290-2
Freimer NB, Slatkin M(1996). Microsatellites: Evolution and mutational processes. CIBA Foundation Symposia (197) 51-72.
10.1002/9780470514887.ch4
Järvelä I, Mitchison HM, Munroe PB, O'Rawe AM, Mole SE, Syvänen AC(1996). Rapid diagnostic test for the major mutation underlying Batten disease. Journal of Medical Genetics vol. 33, (12) 1041-1042.
10.1136/jmg.33.12.1041
McInnes LA, Escamilla MA, Service SK, Reus VI, Leon P, Silva S, Rojas E, Spesny M et al.(1996). A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees. Proceedings of the National Academy of Sciences of the United States of America vol. 93, (23) 13060-13065.
10.1073/pnas.93.23.13060
Scanlon TJ, Luben R, Lyle P(1996). Comparing hypertension guidelines. BMJ vol. 313, (7066)
10.1136/bmj.313.7066.1203
Scanlon TJ, Luben R, Lyle P(1996). Comparing hypertension guidelines. Guidelines are based on evidence from trials, not normal practice. BMJ (Clinical research ed.) vol. 313, (7066)
10.1136/bmj.313.7066.1203
Freimer NB, Reus VI, Escamilla M, Spesny M, Smith L, Service S, Gallegos A, Meza L et al.(1996). An Approach to Investigating Linkage for Bipolar Disorder Using Large Costa Rican Pedigrees. American Journal of Medical Genetics - Seminars in Medical Genetics vol. 67, (3) 254-263.
10.1002/(SICI)1096-8628(19960531)67:3<254::AID-AJMG3>3.0.CO;2-N
Escamilla MA, Spesny M, Reus VI, Gallegos A, Meza L, Molina J, Sandkuijl LA, Fournier E et al.(1996). Use of Linkage Disequilibrium Approaches to Map Genes for Bipolar Disorder in the Costa Rican Population. American Journal of Medical Genetics - Seminars in Medical Genetics vol. 67, (3) 244-253.
10.1002/(SICI)1096-8628(19960531)67:3<244::AID-AJMG2>3.0.CO;2-N
Munroe PB, Rapola J, Mitchison HM, Mustonen A, Mole SE, Gardiner RM, Järvelä I(1996). Prenatal diagnosis of Batten's disease. Lancet vol. 347, (9007) 1014-1015.
10.1016/S0140-6736(96)90148-8
Freimer NB, Reus VI, Escamilla MA, Alison McInnes L, Spesny M, Leon P, Service SK, Smith LB et al.(1996). Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23. Nature Genetics vol. 12, (4) 436-441.
10.1038/ng0496-436
Crouau-Roy B, Service S, Slatkin M, Freimer N(1996). A fine-scale comparison of the human and chimpanzee genomes: Linkage, linkage disequilibrium and sequence analysis. Human Molecular Genetics vol. 5, (8) 1131-1137.
10.1093/hmg/5.8.1131
Di Rienzo A, Peterson AC, Freimer NB(1996). Amplification with arbitrary primers. Methods in molecular biology (Clifton, N.J.) vol. 54, 123-129.
10.1385/0-89603-313-9:123
Smith LB, Sapers B, Reus VI, Freimer NB(1996). Attitudes towards bipolar disorder and predictive genetic testing among patients and providers. Journal of Medical Genetics vol. 33, (7) 544-549.
10.1136/jmg.33.7.544
Knisely AS, Kocoshis S, O'Connell N, Setchell KD, Bull LN, Freimer NB(1996). Deficiency of chenodeoxycholic acid in bile: Byler disease and byler syndrome. Journal of Pediatric Gastroenterology and Nutrition vol. 23, (3)
10.1097/00005176-199610000-00066
Garza JC, Freimer NB(1996). Homoplasy for size at microsatellite loci in humans and chimpanzees. Genome Research vol. 6, (3) 211-217.
10.1101/gr.6.3.211
Sela-Herman S, Bull L, Lomri N, Rahmaoui C, Luther T, Hammerman P, Genant J, Freimer N et al.(1996). In search of a gene for hereditary cholestasis. Biochemical and Molecular Medicine vol. 59, (2) 98-103.
10.1006/bmme.1996.0073
Houwen RHJ, Sinke R, Juyn J, Freimer N, Berger R(1996). Mapping of the gene for bric and byler disease. Journal of Pediatric Gastroenterology and Nutrition vol. 22, (4)
10.1097/00005176-199605000-00035
Freimer NB, Blower S, Slatkin M(1996). Pathogens &amp; strain diversity: Is sex disruptive?. Nature Medicine vol. 2, (4) 401-403.
10.1038/nm0496-401
Munroe PB, Mitchison HM, Dooley TP, Gardiner RM, Mole SE (1995). Analysis of Batten disease candidate genes STP and STM. American Journal of Medical Genetics. vol. 57, 324-326.
10.1002/ajmg.1320570244
Carlton VEH, Knisely AS, Freimer NB(1995). Mapping of a locus for progressive familial intrahepatic cholestasis (byler disease) to 18q21-q22, the benign recurrent intrahepatic cholestasis region. Human Molecular Genetics vol. 4, (6) 1049-1053.
10.1093/hmg/4.6.1049
Peterson AC, Di Rienzo A, Lehesjokl AE, De La Chaelle A, Slatkin M, Frelmer NB(1995). The distribution of linkage disequilibrium over anonymous genome regions. Human Molecular Genetics vol. 4, (5) 887-894.
10.1093/hmg/4.5.887
Munroe PB, Daniel HI, Farrall M, Lawson M, Bouloux PM, Caulfield MJ (1995). Absence of genetic linkage between polymorphisms of the insulin receptor gene and essential hypertension. Journal of Human Hypertension. vol. 9, 669-670.
McInnes LA, Freimer NB(1995). Mapping genes for psychiatric disorders and behavioral traits. Current Opinion in Genetics and Development vol. 5, (3) 376-381.
10.1016/0959-437X(95)80054-9
Garza JC, Slatkin M, Freimer NB(1995). Microsatellite allele frequencies in humans and chimpanzees, with implications for constraints on allele size. Molecular Biology and Evolution vol. 12, (4) 594-603.
10.1093/oxfordjournals.molbev.a040239
JäRvelä IE, Mitchison HM, O¿Rawe AM, Munroe PB, Taschner PEM, Devos N, Lerner TJ, D¿Arigo KL et al.(1995). YAC and cosmid contigs spanning the batten disease (CLN3) region at 16p12.1-p11.2. Genomics vol. 29, (2) 478-489.
10.1006/geno.1995.9978
Caulfield M, Lavender P, Farrall M, Munroe P, Lawson M, Turner P, Clark AJL(1994). Linkage of the angiotensinogen gene to essential hypertension. New England Journal of Medicine vol. 330, (23) 1629-1633.
10.1056/NEJM199406093302301
Di Rienzo A, Peterson AC, Garza JC, Valdes AM, Slatkin M, Freimer NB(1994). Mutational processes of simple-sequence repeat loci in human populations. Proceedings of the National Academy of Sciences of the United States of America vol. 91, (8) 3166-3170.
10.1073/pnas.91.8.3166
Kamdar S, Daniel H, Fogarty P, Lawson M, Munroe P, Caulfield M (1994). ACE insertion/deletion (I/D) polymorphism in Vincentian African Caribbeans with essential hypertension. Journal of Human Hypertension. vol. 8,
Houwen RHJ, Baharloo S, Blankenship K, Raeymaekers P, Juyn J, Sandkuijl LA, Freimer NB(1994). Genome screening by searching for shared segments: Mapping a gene for benign recurrent intrahepatic cholestasis. Nature Genetics vol. 8, (4) 380-386.
10.1038/ng1294-380
Dooley TP, Probst P, Munroe PB, Mole SE, Liu Z, Doggett NA(1994). Genomic organization and DNA sequence of the human catecholamine-sulfating phenol sulfotransferase gene (STM). Biochemical and Biophysical Research Communications vol. 205, (2) 1325-1332.
10.1006/bbrc.1994.2810
Munroe PB, Johnston A, Duke VM, Daniel HI, Bouloux PM, Lawson M, Caulfield MJ (1994). Investigation of lipoprotein lipase (LPL) as a candidate gene for dyslipidaemic hypertension. Journal of Human Hypertension. vol. 8, 613-614.
Daniel HI, Munroe PB, Lawson M, Fogarty P, Kamdar SM, Caulfield MJ (1994). Investigation of the renin gene as a putative locus for essential hypertension (EH) in Vincentian African Caribbeans. Journal of Human Hypertension. vol. 8, 609-610.
Dooley TP, Mitchison HM, Munroe PB, Probst P, Neal M, Siciliano MJ, Deng ZM, Doggett NA et al.(1994). Mapping of Two Phenol Sulfotransferase Genes, STP and STM, to 16p: Candidate Genes for Batten Disease. Biochemical and Biophysical Research Communications vol. 205, (1) 482-489.
10.1006/bbrc.1994.2691
Di Rienzo A, Peterson A, Das S, Freimer NB(1993). Genome mapping by arbitrary amplification of yeast artificial chromosomes. Mammalian Genome vol. 4, (7) 359-363.
10.1007/BF00360585
Valdes AM, Slatkin M, Freimer NB(1993). Allele frequencies at microsatellite loci: The stepwise mutation model revisited. Genetics vol. 133, (3) 737-749.
Munroe PB, Caulfield M, Daniel H, Lawson M, Bouloux PMG, Turner P (1993). Analysis of the insulin receptor RsaI polymorphism in essential hypertension. British Journal of Clinical Pharmacology. vol. 35,
Bouloux PG, Kirk J, Munroe P, Duke V, Meindl A, Hilson A, Grant D, Carter N et al.(1993). Deletion analysis maps ocular albinism proximal to the steroid sulphatase locus. Clinical Genetics vol. 43, (4) 169-173.
10.1111/j.1399-0004.1993.tb04442.x
Freimer NB, Sandkuijl LA, Blower SM(1993). Incorrect specification of marker allele frequencies: Effects on linkage analysis. American Journal of Human Genetics vol. 52, (6) 1102-1110.
Scanlon TJ, Luben RN, Scanlon FL, Singleton N(1993). Is Friday the 13th bad for your health?. British Medical Journal vol. 307, (6919) 1584-1586.
10.1136/bmj.307.6919.1584
Consalez GG, Stayton CL, Freimer NB, Goonewardena P, Brown WT, Gilliam TC, Warren ST(1992). Isolation and characterization of a highly polymorphic human locus (DXS455) in proximal Xq28. Genomics vol. 12, (4) 710-714.
10.1016/0888-7543(92)90299-8
Bouloux PMG, Munroe P, Kirk J, Besser GM(1992). Sex and smell - An enigma resolved. Journal of Endocrinology vol. 133, (3) 323-326.
10.1677/joe.0.1330323
Bouloux PMG, Hardelin JP, Munroe P, Kirk JMW, Legouis R, Levilliers J, Hazan J, Weissenbach J et al.(1991). A dinucleotide repeat polymorphism at the kallmann locus (Xp22.3). Nucleic Acids Research vol. 19, (19)
10.1093/nar/19.19.5453
Kleyn PW, Brzustowicz LM, Wilhelmsen KA, Freimer NB, Miller JM, Munsat TL, Gilliam TC(1991). Spinal muscular atrophy is not the result of mutations at the beta–hexosaminidase or GM<inf>2</inf>–activator locus. Neurology vol. 41, (9) 1418-1422.
10.1212/wnl.41.9.1418
Gilliam TC, Freimer NB, Kaufmann CA, Powchik PP, Bassett AS, Bengtsson U, Wasmuth JJ(1989). Deletion mapping of DNA markers to a region of chromosome 5 that cosegregates with schizophrenia. Genomics vol. 5, (4) 940-944.
10.1016/0888-7543(89)90138-9
Freimer N, Lu F, Chen J(1989). Posttraumatic stress and conversion disorders in a Laotian Refugee veteran: Use of Amobarbital interviews. Journal of Nervous and Mental Disease vol. 177, (7) 432-433.
10.1097/00005053-198907000-00008
Return to top