Publications: Prof David Lee

Heywood HK, Thorpe SD, Jeropoulos RM, Caton PW, Lee DA ( 2023 ) . Modulation of sirtuins during monolayer chondrocyte culture influences cartilage regeneration upon transfer to a 3D culture environment . Frontiers in Bioengineering and Biotechnology vol. 10 ,

Heywood HK, Gardner L, Knight MM, Lee DA ( 2022 ) . Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems . In vitro models1 - 8 .

Brookes O, Thorpe SD, Evans OR, Keeling MC, Lee DA ( 2022 ) . Covariation of Pluripotency Markers and Biomechanical Properties in Mouse Embryonic Stem Cells . Frontiers in Cell and Developmental Biology vol. 10 ,

Lachowski D, Cortes E, Matellan C, Rice A, Lee DA, Thorpe SD, del Río Hernández AE ( 2021 ) . G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization . Frontiers in Cell and Developmental Biology vol. 8 , 592628 - 592628 .

Rice A, Cortes E, Lachowski D, Oertle P, Matellan C, Thorpe SD, Ghose R, Wang H et al. ( 2020 ) . GPER activation inhibits cancer cell mechanotransduction and basement membrane invasion via RhoA . Cancers vol. 12 , ( 2 )

Thorpe S, Chronopoulos A, Cortes E, Lachowski D, Rice A, Mykuliak V, Róg T, Lee D et al. ( 2020 ) . Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway . Nature Materials

Cortes E, Lachowski D, Rice A, THORPE SD, Robinson B, Yeldag G, LEE DA, Ghemtio L et al. ( 2018 ) . Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor . Oncogene

Cortes E, Lachowski D, Robinson B, Sarper M, Teppo JS, Thorpe SD, Lieberthal TJ, Iwamoto K et al. ( 2018 ) . Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival . EMBO Reports vol. 20 , ( 1 )

Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe SD, Lee DA, Hernández AER ( 2018 ) . GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment . EMBO Reports vol. 20 , ( 1 )

Cortes E, Lachowski D, Rice A, Chronopoulos A, Robinson B, THORPE SD, LEE DA, Possamai LA et al. ( 2018 ) . RAR‐β is downregulated in HCC & cirrhosis and its expression inhibits myosin‐driven activation and durotaxis in hepatic stellate cells . Hepatology

Bader DL, Lee DA, Knight MM ( 2017 ) . Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2) . The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME vol. 2005.18 , ( 0 ) 2 - 3 .

Elyasigomari V, Lee DA, Screen HRC, SHAHEED MH ( 2017 ) . Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification . Journal of Biomedical Informatics vol. 67 , ( 2017 ) 11 - 20 .

THORPE SD, Lee DA ( 2017 ) . Dynamic regulation of nuclear architecture and mechanics—a rheostatic role for the nucleus in tailoring cellular mechanosensitivity . Nucleus vol. 8 , ( 3 ) 287 - 300 .

Eraifej J, Thorpe SD, Martins RP, Lee DA ( 2017 ) . Does lamin A/C play a role in neuronal differentiation? . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 98 , A12 - A12 .

Heywood HK, Thorpe SD, Jeropoulos RM, Lee DA ( 2017 ) . Small molecule activators of SIRT1 augment the regenerative potential of chondrocytes for cell-based cartilage repair techniques . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 98 , A14 - A14 .

Thorpe SD, Oti A, Mauck RL, Lee DA ( 2017 ) . Stem cell differentiation state modulates Lamin AC localization and phosphorylation in response to cyclic tensile strain . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 98 , A13 - A14 .

Panesar KS, Thorpe SD, Lee DA ( 2017 ) . Uniaxial tensile strain modulates mesenchymal stem cell nuclear structure and histone methylation in a differentiation dependent manner . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 98 , A11 - A12 .

Heo S-J, Driscoll TP, Thorpe SD, Nerurkar NL, Baker BM, Yang MT, Chen CS, Lee DA et al. ( 2016 ) . Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity . eLife vol. 5 ,

Tilwani RK, Vessillier S, Pingguan-Murphy B, Lee DA, Bader DL, Chowdhury TT ( 2016 ) . Oxygen tension modulates the effects of TNFα in compressed chondrocytes . Inflamm Res

Heo SJ, Han WM, Szczesny SE, Cosgrove BD, Elliott DM, Lee DA, Duncan RL, Mauck RL ( 2016 ) . Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells . Biophysical Journal vol. 111 , ( 4 ) 864 - 874 .

Lee D ( 2016 ) . A Tour through through . Journal of English Linguistics vol. 26 , ( 4 ) 333 - 351 .

Lee D ( 2016 ) . States rights and Australia’s adoption of the statute of Westminster, 1931–1942 . History Australia vol. 13 , ( 2 ) 258 - 274 .

Lee D, Recce M ( 2016 ) . Quantitative Evaluation of the Exploration Strategies of a Mobile Robot . The International Journal of Robotics Research vol. 16 , ( 4 ) 413 - 447 .

Heywood HK, Lee DA ( 2016 ) . Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen . Journal of Tissue Engineering and Regenerative Medicine vol. 11 , ( 8 ) 2286 - 2294 .

Sliogeryte K, Botto L, Lee DA, Knight MM ( 2016 ) . Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion . Osteoarthritis and Cartilage vol. 24 , ( 5 ) 912 - 920 .

Lee D ( 2016 ) . Reluctant relaxation . History Australia vol. 10 , ( 3 ) 149 - 170 .

Heywood HK, Caton PW, Lee DA ( 2016 ) . SIRT1, an enzyme vital to cartilage homeostasis, is regulated by osmolarity and glucose levels . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 97 , A2 - A2 .

Theocharidis G, Drymoussi Z, Kao AP, Barber AH, Lee DA, Braun KM, Connelly JT ( 2016 ) . Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility . Journal of Investigative Dermatology vol. 136 , ( 1 ) 74 - 83 .

Theocharidis G, Drymoussi Z, Kao AP, Barber AH, Lee DA, Braun KM, Connelly JT ( 2016 ) . Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility . J Invest Dermatol vol. 136 , ( 1 ) 74 - 83 .

Heo S-J, Thorpe SD, Driscoll TP, Duncan RL, Lee DA, Mauck RL ( 2015 ) . Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells . Scientific Reports vol. 5 , ( 1 )

CHEN J, BADER DL, LEE DA, KNIGHT MM ( 2015 ) . FINITE ELEMENT ANALYSIS OF MECHANICAL DEFORMATION OF CHONDROCYTE TO 2D SUBSTRATE AND 3D SCAFFOLD . Journal of Mechanics in Medicine and Biology vol. 15 , ( 05 )

Sliogeryte K, Thorpe SD, Lee DA, Botto L, Knight MM ( 2014 ) . Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics . Scientific Reports vol. 4 , ( 1 )

Irianto J, Lee DA, Knight MM ( 2014 ) . Quantification of chromatin condensation level by image processing . Med Eng Phys vol. 36 , ( 3 ) 412 - 417 .

Heywood HK, Nalesso G, Lee DA, Dell'accio F ( 2014 ) . Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture . Biores Open Access vol. 3 , ( 1 ) 9 - 18 .

Tilwani RK, Lee DA, Pingguan-Murphy B, Abas WABW, Chowdhury TT ( 2014 ) . Hypoxia amplified catabolic effects induced by TNFα in chondrocytes - response reduced with biomechanical signals . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 95 , A33 - A34 .

Thorpe SD, Lee DA ( 2014 ) . Mesenchymal stem cell nuclear architecture is differentially regulated by lineage commitment and mechanical stimulation . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 95 , A33 - A33 .

Heywood HK, Lee DA ( 2014 ) . Reactive oxygen species drive the transformation to an oxidative energy metabolism in cultured articular chondrocytes . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 95 , A15 - A16 .

Huang J, Hing KA, Best SM, Lee DA, Silvio LD, Bonfield W ( 1999 ) . A COMPARATIVE STUDY OF VARIOUS ASSAYS FOR IN VITRO BIOCOMPATIBILITY ASSESSMENT OF EXPERIMENTAL ZIRCONIA . Conference: Bioceramics199 - 202 .

Irianto J, Swift J, Martins RP, McPhail GD, Knight MM, Discher DE, Lee DA ( 2013 ) . Osmotic challenge drives rapid and reversible chromatin condensation in chondrocytes . Biophys J vol. 104 , ( 4 ) 759 - 769 .

Pattappa G, Thorpe SD, Jegard NC, Heywood HK, de Bruijn JD, Lee DA ( 2013 ) . Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells . TISSUE ENGINEERING PART C-METHODS vol. 19 , ( 1 )

Sillitoe I, Cuff AL, Dessailly BH, Dawson NL, Furnham N, Lee D, Lees JG, Lewis TE et al. ( 2012 ) . New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures . Nucleic Acids Research vol. 41 , ( D1 ) d490 - d498 .

Chen J, Irianto J, Inamdar S, Pravincumar P, Lee DA, Bader DL, Knight MM ( 2012 ) . Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment . Biophys J vol. 103 , ( 6 ) 1188 - 1197 .

Bonzani IC, Campbell JJ, Knight MM, Williams A, Lee DA, Bader DL, Stevens MM ( 2012 ) . Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: a case study . J Mech Behav Biomed Mater vol. 11 , 72 - 81 .

Branford OA, Lee DA, Rolfe KJ, Grobbelaar AO ( 2012 ) . The attachment of intrinsic and extrinsic, mobilized and immobilized adhesion cells to collagen and fibronectin . Journal of Hand Surgery: European Volume vol. 37 , ( 6 ) 564 - 572 .

Branford OA, Lee DA, Bader DL, Grobbelaar AO ( 2012 ) . The mechanics of flexor tendon adhesions . Journal of Hand Surgery: European Volume vol. 37 , ( 6 ) 555 - 563 .

Lee D, Smallbone K, Dunn WB, Murabito E, Winder CL, Kell DB, Mendes P, Swainston N ( 2012 ) . Improving metabolic flux predictions using absolute gene expression data . BMC Systems Biology vol. 6 , ( 1 )

Figliolini A, Archuletta M, LeClaire J, Brinkley D, Doerr D, White R, Bozak R, Lee DA ( 2012 ) . Through pellicle management of haze formation in a wafer fabrication environment . Proceedings of SPIE--the International Society for Optical Engineering . Conference: 28th European Mask and Lithography Conference vol. 8352 ,

Maeda E, Ye S, Wang W, Bader DL, Knight MM, Lee DA ( 2012 ) . Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading . Biomechanics and Modeling in Mechanobiology vol. 11 , ( 3-4 ) 439 - 447 .

Lee D ( 2012 ) . Stanley Melbourne Bruce in London, 1938–41 . The Journal of Imperial & Commonwealth History vol. 40 , ( 1 ) 45 - 65 .

Gutowski IA, Lee D, de Bruyn JR, Frisken BJ ( 2012 ) . Scaling and mesostructure of Carbopol dispersions . Rheologica Acta vol. 51 , ( 5 ) 441 - 450 .

Martins RP, Finan JD, Guilak F, Lee DA ( 2012 ) . Mechanical regulation of nuclear structure and function . Annu Rev Biomed Eng vol. 14 , 431 - 455 .

Hosny NA, Lee DA, Knight MM ( 2012 ) . Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations . J Biomed Opt vol. 17 , ( 1 )

Jaimes N, Scope A, Welzel J, Wang KX, Lee DA, Siegel DM, Marghoob AA ( 2011 ) . White Globules in Melanocytic Neoplasms: In Vivo and Ex Vivo Characteristics . Dermatologic Surgery vol. 38 , ( 1 ) 128 - 132 .

Robinson T, Yi D, Brinkley D, Roessler K, White R, Bozak R, Archuletta M, Lee D ( 2011 ) . Clean and repair of EUV photomasks . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask Technology 2011 vol. 8166 ,

Pattappa G, Heywood HK, de Bruijn JD, Lee DA ( 2011 ) . The metabolism of human mesenchymal stem cells during proliferation and differentiation . J Cell Physiol vol. 226 , ( 10 ) 2562 - 2570 .

Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH, Screen HRC ( 2011 ) . Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment . Proc Inst Mech Eng H vol. 225 , ( 8 ) 821 - 830 .

Moses SE, Osborne W, Valappil M, Collin M, Lee D, Waugh S, Jackson G, Parry CM et al. ( 2011 ) . Extensive oral herpes simplex virus type 1 infection in a haematopoietic stem cell transplant recipient not responding to aciclovir . Journal of Clinical Virology vol. 52 , ( 2 ) 67 - 69 .

Lee D, Gutowski IA, Bailey AE, Rubatat L, de Bruyn JR, Frisken BJ ( 2011 ) . Investigating the microstructure of a yield-stress fluid by light scattering . Physical Review E vol. 83 , ( 3 )

Lee D, de Beer TA, Laskowski RA, Thornton JM, Orengo CA ( 2011 ) . 1,000 structures and more from the MCSG . BMC Molecular and Cell Biology vol. 11 , ( 1 )

Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH, Screen HRC ( 2011 ) . Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment . P I MECH ENG H vol. 225 , ( H8 ) 821 - 830 .

Martyn SV, Heywood HK, Rockett P, Paine MD, Wang MJ, Dobson PJ, Sheard SJ, Lee DA et al. ( 2011 ) . Electrospray deposited fibronectin retains the ability to promote cell adhesion . Journal of Biomedical Materials Research - Part B Applied Biomaterials vol. 96 B , ( 1 ) 110 - 118 .

Chen J, Bader DL, Lee DA, Knight MM ( 2011 ) . Finite Element Modeling of Cell Deformation When Chondrocyte Seeded Agarose Is Subjected to Compression . 8TH INTERNATIONAL CONFERENCE ON CELL & STEM CELL ENGINEERING (ICCE) . vol. 30 , 17 - 20 .

Maeda E, Ye S, Wang W, Bader DL, Knight MM, Lee DA ( 2011 ) . Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading . Biomechanics and Modeling in Mechanobiology1 - 9 .

Lee DA, Siegel DM ( 2011 ) . Novel devices for diagnosis and treatment . Journal of Drugs in Dermatology vol. 10 , ( 1 ) 21 - 22 .

Lee DA, Brand J, Salter D, Akanji O-O, Chowdhury TT ( 2011 ) . Quantification of mRNA using real-time PCR and Western blot analysis of MAPK events in chondrocyte/agarose constructs . Methods Mol Biol vol. 695 , 77 - 97 .

Lee DA, Knight MM, Campbell JJ, Bader DL ( 2011 ) . Stem cell mechanobiology . J Cell Biochem vol. 112 , ( 1 ) 1 - 9 .

Pattappa G, Heywood HK, de Bruijn JD, Lee DA ( 2010 ) . The metabolism of human mesenchymal stem cells during proliferation and differentiation . J Cell Physiol

Lee DA, Randall F, Beattie G, Bentall RP ( 2010 ) . Delusional discourse: An investigation comparing the spontaneous causal attributions of paranoid and non‐paranoid individuals . Psychology and Psychotherapy Theory Research and Practice vol. 77 , ( 4 ) 525 - 540 .

Lee D, Schroeder J ( 2010 ) . Phenotypic analysis of Arabidopsis mutants: heavy metal stress . Cold Spring Harbor Protocols vol. 2008 , ( 9 )

Maeda E, Fleischmann C, Mein CA, Shelton JC, Bader DL, Lee DA ( 2010 ) . Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain . Connective Tissue Research vol. 51 , ( 6 ) 434 - 444 .

Heywood HK, Knight MM, Lee DA ( 2010 ) . Both superficial and deep zone articular chondrocyte subpopulations exhibit the crabtree effect but have different basal oxygen consumption rates . Journal of Cellular Physiology vol. 223 , ( 3 ) 630 - 639 .

Lee D ( 2010 ) . Giving something back . Twist ( 22 ) 28 - 30 .

Robinson T, Yi D, White R, Bozak R, Archuletta M, Lee D ( 2010 ) . Nanomachining of non-orthogonal mask patterns . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask and Next-Generation Lithography Mask Technology XVII vol. 7748 ,

Robinson T, White R, Bozak R, LeClaire J, Archuletta M, Lee D ( 2010 ) . Through-pellicle defect repair for advanced photomasks . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask and Next-Generation Lithography Mask Technology XVII vol. 7748 ,

Ye S, Maeda E, Knight M, Lee D, Bader D, Wang W ( 2010 ) . A compartment model to evaluate the permeability of gap junctions between tenocytes in tendon fascicles . The FASEB Journal vol. 24 , ( S1 ) 975.9 - 975.9 .

Ku T, LeClaire J, Tan SK, Chua GS, Bozak R, White R, Robinson T, Archuletta M et al. ( 2010 ) . Preliminary results for photomask haze mitigation in a fab environment . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Metrology, Inspection, and Process Control for Microlithography XXIV vol. 7638 ,

Hosny NA, Lee DA, Knight MM ( 2010 ) . Extracellular oxygen concentration mapping with confocal multiphoton laser scanning microscope and TCSPC card . MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES X . Editors: Periasamy, A, So, PTC, Konig, K , vol. 7569 ,

Heywood HK, Lee DA ( 2010 ) . Low oxygen reduces the modulation to an oxidative phenotype in monolayer-expanded chondrocytes . J Cell Physiol vol. 222 , ( 1 ) 248 - 253 .

Maeda E, Shelton JC, Bader DL, Lee DA ( 2009 ) . Effect of intermittent cyclic tensile strain on collagen synthesis by tenocytes in isolated fascicles . Journal of Biomechanical Science and Engineering vol. 4 , ( 4 ) 510 - 517 .

Lee DA, Rentzsch R, Orengo C ( 2009 ) . GeMMA: functional subfamily classification within superfamilies of predicted protein structural domains . Nucleic Acids Research vol. 38 , ( 3 ) 720 - 737 .

Robinson T, White R, Bozak R, Roessler K, Arruza B, Hogle D, Archuletta M, Lee D ( 2009 ) . New tools to enable photomask repair to the 32nm node . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask Technology 2009 vol. 7488 ,

Pattappa G, Jegard NC, Lee DA, de Bruijn JD ( 2009 ) . The effect of oxygen tension on the proliferation and differentiation of human mesenchymal stem cells . European Cells and Materials vol. 18 , ( SUPPL. 1 )

Mcleod R, Pattappa G, Irianto J, Awan M, Knight MM, Lee DA ( 2009 ) . Graded hydrogel constructs for cartilage tissue engineering . European Cells and Materials . vol. 18 ,

Campbell JJ, Maeda E, Ye SJ, Wang W, Lee DA ( 2009 ) . Osteogenic differentiation of human mesenchymal stem cells within a perfused bioreactor system . European Cells and Materials vol. 18 , ( SUPPL. 2 )

Pattappa G, Jegard NC, de Bruijn JD, Lee DA ( 2009 ) . The influence of oxygen tension on the colony formation and proliferation of human mesenchymal stem cells . European Cells and Materials vol. 18 , ( SUPPL. 2 )

Robinson T, Bozak R, White R, Archuletta M, Lee D ( 2009 ) . Selective removal of persistent particles with no photomask damage . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask and Next-Generation Lithography Mask Technology XVI vol. 7379 ,

Pearl FMG, Lee D, Bray JE, Buchan DWA, Shepherd AJ, Orengo CA ( 2009 ) . The CATH extended protein‐family database: Providing structural annotations for genome sequences . Protein Science vol. 11 , ( 2 ) 233 - 244 .

Maeda E, Shelton JC, Bader DL, Lee DA ( 2009 ) . Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro . Journal of Applied Physiology vol. 106 , ( 2 ) 506 - 512 .

Berry CC, Shelton JC, Lee DA ( 2009 ) . Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs . J Tissue Eng Regen Med vol. 3 , ( 1 ) 43 - 53 .

Eniwumide JO, Lee DA, Bader DL ( 2009 ) . The development of a bioreactor to perfuse radially-confined hydrogel constructs: design and characterization of mass transport properties . Biorheology vol. 46 , ( 5 ) 417 - 437 .

Pattappa G, A. Lee D, De Bruijn JD ( 2008 ) . Metabolic characteristics of human mesenchymal stem cells expanded under normoxic conditions . 8th World Biomaterials Congress 2008 vol. 1 ,

Lee S-Y, Kim G-B, Sim H-S, Lee S-H, Kim H-S, Lee J-H, Seo H-S, Han H-S et al. ( 2008 ) . Analysis of process margin in EUV mask repair with nano-machining . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask Technology 2008 vol. 7122 ,

Heywood HK, Lee DA ( 2008 ) . Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes . Biochem Biophys Res Commun vol. 373 , ( 2 ) 224 - 229 .

Maeda E, Shelton JC, Bader DL, Lee DA ( 2008 ) . Collagen synthesis by tenocytes in fascicles subjected to intermittent cyclic strain . European Cells and Materials vol. 16 , ( SUPPL. 3 )

Chowdhury TT, Salter DM, Bader DL, Lee DA ( 2008 ) . Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression . INFLAMM RES vol. 57 , ( 7 ) 306 - 313 .

Heywood HK, Lee DA ( 2008 ) . The effect of oxygen supply on chondrocyte metabolic phenotype during monolayer culture . European Cells and Materials vol. 16 , ( SUPPL. 3 )

Hughes D, Whitaker Y, Lee D, Eckhause J ( 2008 ) . Advantages, Disadvantages, and Uses of Generalized Activity Networks for Schedule Estimation . Military Operations Research vol. 13 , ( 3 ) 27 - 40 .

Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM, Lee DA ( 2008 ) . Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs . Arthritis Res Ther vol. 10 , ( 2 )

Chowdhury TT, Akanji OO, Salter DM, Bader DL, Lee DA ( 2008 ) . Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression . BIORHEOLOGY vol. 45 , ( 3-4 ) 257 - 274 .

Campbell JJ, Bader DL, Lee DA ( 2008 ) . Mechanical loading modulates intracellular calcium signaling in human mesenchymal stem cells . J APPL BIOMATER BIOM vol. 6 , ( 1 ) 9 - 15 .

Lee DA ( 2008 ) . Surgeons carry out first implant of pulmonary human heart valve . Biomedical Materials ( MAY )

Akanji OO, Lee DA, Bader DA ( 2008 ) . The effects of direct current stimulation on isolated chondrocytes seeded in 3D agarose constructs . BIORHEOLOGY . vol. 45 , 229 - 243 .

Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL, Lee DA ( 2007 ) . 52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION . Osteoarthritis and Cartilage vol. 15 , c42 - c43 .

Lee D, Redfern O, Orengo C ( 2007 ) . Predicting protein function from sequence and structure . Nature Reviews Molecular Cell Biology vol. 8 , ( 12 ) 995 - 1005 .

Chen Y-H, Chang H-H, Chen Y-J, Lee D, Chiang H-H, Jane Yao C-C ( 2007 ) . Root contact during insertion of miniscrews for orthodontic anchorage increases the failure rate: an animal study . Clinical Oral Implants Research vol. 0 , ( 0 ) 071025001541005 - ??? .

Maeda E, Shelton JC, Bader DL, Lee DA ( 2007 ) . Time dependence of cyclic tensile strain on collagen production in tendon fascicles . BIOCHEM BIOPH RES CO vol. 362 , ( 2 ) 399 - 404 .

White R, Dinsdale A, Robinson T, Brinkley D, Csuy J, Lee D ( 2007 ) . Repairing 45 nm node defects through nano-machining . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask Technology 2007 vol. 6730 ,

Bonzani IC, Knight MM, Lee DA, Bader DL, Williams A, Stevens MM ( 2007 ) . A model for studying the influence of mechanical loading on human periosteal stem cells . TISSUE ENGINEERING . vol. 13 , 1636 - 1636 .

Heywood HK, Lee DA ( 2007 ) . Development of an immunoassay for determination of adsorbed fibronectin levels on bio-functionalised substrates . TISSUE ENGINEERING . vol. 13 , 1669 - 1670 .

Chowdhury TT, Akanji OO, Arghandawi, Salter DM, Bader DL, Lee DA ( 2007 ) . Dynamic compression counteracts IL-1 beta b induced iNOS and COX-2 expression in chondrocytes cultured in agarose constructs . TISSUE ENGINEERING . vol. 13 , 1677 - 1677 .

Maeda E, Shelton JC, Bader DL, Lee DA ( 2007 ) . Gene expressions in tendon fascicles subjected to cyclic tensile strain . TISSUE ENGINEERING . vol. 13 , 1701 - 1701 .

Campbell JJ, Bader DL, Lee DA ( 2007 ) . Mechanical loading modulates calcium signalling within mesenchymal stem cells . TISSUE ENGINEERING . vol. 13 , 1722 - 1723 .

Pattappa G, De Bruijn JD, Lee DA ( 2007 ) . Mesenchymal stem cells maintain a glycolytic metabolism under normoxic conditions . TISSUE ENGINEERING . vol. 13 , 1725 - 1725 .

Mcleod R, Pattappa G, Irianto J, Knight MM, Lee DA ( 2007 ) . The development and characterisation of chondrocyte-seeded gradient hydrogel constructs for cartilage tissue engineering . TISSUE ENGINEERING . vol. 13 , 1763 - 1763 .

Lee DA ( 2007 ) . Industry news: CryoLife signs Irish distribution deal with Proxy Biomedical . Biomedical Materials ( NOV. ) 6 - 7 .

Lee DA ( 2007 ) . Products: CryoLife wins US patent for foam wound sealant . Biomedical Materials ( JULY )

Lee DA, Hall J ( 2007 ) . Products: CryoLife wins rights to distribute replacement pericardium . Biomedical Materials ( MAR. )

Heywood HK, Bader DL, Lee DA ( 2006 ) . Glucose concentration and medium volume influence cell viability and glycosaminoglycan synthesis in chondrocyte-seeded alginate constructs . Tissue Eng . vol. 12 , 3487 - 3496 .

Lee DA, Herbiet R ( 2006 ) . New aluminum hydroxide and magnesium hydroxide grades with enhanced flame retardancy . Society of Petroleum Engineers International Conference on Polyolefins 2006: From Reserves to Retailers - The Changes Confronting the Polyolefins Business Worldwide . vol. 2 , 842 - 878 .

Heywood HK, Bader DL, Lee DA ( 2006 ) . Glucose Concentration and Medium Volume Influences Cell Viability and Glycosaminoglycan Synthesis in Chondrocyte-Seeded Alginate Constructs . Tissue Engineering vol. 0 , ( 0 )

Robinson T, Lewellen J, Lee DA, Brooker P ( 2006 ) . Impact of AFM scan artifacts on photolithographic simulation . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask Technology 2006 vol. 6349 ,

White R, LeClaire J, Robinson T, Dinsdale A, Bozak R, Lee DA ( 2006 ) . Precise and high-throughput femtopulse laser mask repair of large defects . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask Technology 2006 vol. 6349 ,

Gao J, Yang Y, Lee D, Holdcroft S, Frisken BJ ( 2006 ) . Self-Assembly of Latex Particles into Proton-Conductive Membranes . Macromolecules vol. 39 , ( 23 ) 8060 - 8066 .

Screen HRC, Chhaya VH, Greenwald SE, Bader DL, Lee DA, Shelton JC ( 2006 ) . The influence of swelling and matrix degradation on the microstructural integrity of tendon . Acta Biomater vol. 2 , ( 5 ) 505 - 513 .

BRANFORD O, LEE D, BADER D, GROBBELAAR A ( 2006 ) . 1.3 The quantitative assessment of flexor tendon adhesion – a novel use of confocal microscopy to evaluate local strain, orientation and organisation . Journal of Hand Surgery (European Volume) vol. 31 , 3 - 3 .

Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA, Bader DL ( 2006 ) . Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields . BIOMECH MODEL MECHAN vol. 5 , ( 2-3 ) 180 - 191 .

Akanji OO, Bader DL, Lee DA ( 2006 ) . Direct current influences Ca ²⁺ signalling in chondrocytes . European Cells and Materials vol. 11 , ( SUPPL.2 )

Chowdhury TT, Appleby RN, Salter DM, Bader DA, Lee DA ( 2006 ) . Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes . Biomech Model Mechanobiol vol. 5 , ( 2-3 ) 192 - 201 .

Robinson T, Lewellen J, Bozak R, Lee DA, Brooker P ( 2006 ) . Application of photolithographic simulation and a mask repair system in a production environment . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask and Next-Generation Lithography Mask Technology XIII vol. 6283 ,

Ghadiali F, Tolani V, Nagpal R, Robinson T, LeClaire J, Bozak R, Lee DA, White R ( 2006 ) . Femtopulse laser-based mask repair in the DUV wavelength regime . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask and Next-Generation Lithography Mask Technology XIII vol. 6283 ,

Lee D ( 2006 ) . Ground plans [13] . Professional Engineering vol. 19 , ( 6 )

Marsden RL, Lee D, Maibaum M, Yeats C, Orengo CA ( 2006 ) . Comprehensive genome analysis of 203 genomes provides structural genomics with new insights into protein family space . Nucleic Acids Research vol. 34 , ( 3 ) 1066 - 1080 .

Marsden RL, Ranea JAG, Sillero A, Redfern O, Yeats C, Maibaum M, Lee D, Addou S et al. ( 2006 ) . Exploiting protein structure data to explore the evolution of protein function and biological complexity . Philosophical Transactions of the Royal Society B Biological Sciences vol. 361 , ( 1467 ) 425 - 440 .

Heywood HK, Bader DL, Lee DA ( 2006 ) . Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration . Journal of Cellular Physiology vol. 206 , ( 2 ) 402 - 410 .

Chowdhury TT, Bader DL, Lee DA ( 2006 ) . Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes . Biochem Biophys Res Commun vol. 339 , ( 1 ) 241 - 247 .

Enobakhare B, Bader DL, Lee DA ( 2006 ) . Concentration and M/G ratio influence the physiochemical and mechanical properties of alginate constructs for tissue engineering . J Appl Biomater Biomech vol. 4 , ( 2 ) 87 - 96 .

Chowdhury TT, Bader DL, Lee DA ( 2006 ) . Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs . Biorheology vol. 43 , ( 3,4 ) 413 - 429 .

Campbell JJ, Lee DA, Bader DL ( 2006 ) . Dynamic compressive strain influences chondrogenic gene expression in human mesenchymal stem cells . BIORHEOLOGY . vol. 43 , 455 - 470 .

Lee DA ( 2006 ) . Government: US law ensures funding for protein hydrogel development . Biomedical Materials ( DEC. )

Lee DA, Gridley A ( 2006 ) . Industry news: CryoLife, BioForm sign glue deal . Biomedical Materials ( DEC. ) 7 - 8 .

Knight MM, Toyoda T, Lee DA, Bader DL ( 2006 ) . Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose . J Biomech vol. 39 , ( 8 ) 1547 - 1551 .

Chowdhury TT, Raveenthiran SP, Bader DL, Lee DA ( 2006 ) . P140 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN FRAGMENT INDUCED UPREGULATION OF NITRIC OXIDE . Osteoarthritis and Cartilage vol. 14 ,

Lee DA ( 2006 ) . Products: Spinal implant looks good so far . Biomedical Materials ( JUNE ) 4 - 5 .

Lee DA ( 2006 ) . Spinal implants: CryoLife's spinal disc repair study completes enrolment . Biomedical Materials ( SEP. ) 9 - 10 .

Yeats C, Maibaum M, Marsden R, Dibley M, Lee D, Addou S, Orengo CA ( 2005 ) . Gene3D: modelling protein structure, function and evolution . Nucleic Acids Research vol. 34 , ( suppl_1 ) d281 - d284 .

Pingguan-Murphy B, Lee DA, Bader DL, Knight MM ( 2005 ) . Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles . Arch Biochem Biophys vol. 444 , ( 1 ) 45 - 51 .

Screen HRC, Bader DL, Shelton JC, Lee DA ( 2005 ) . Cyclic mechanical conditioning of isolated tendon fascicles results in an upregulation of collagen production . Proceedings of the 2005 Summer Bioengineering Conference vol. 2005 , 193 - 194 .

Pingguan B, Lee DA, Bader DL, Knight MM ( 2005 ) . Dynamic compression activates chondrocyte calcium signaling in a cycle dependent manner involving the release of ATP . Proceedings of the 2005 Summer Bioengineering Conference . vol. 2005 , 223 - 224 .

Chowdhury TT, Bader DL, Lee DA ( 2005 ) . Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs . Proceedings of the 2005 Summer Bioengineering Conference vol. 2005 , 251 - 252 .

Wang MJ, Heywood HK, Bader DL, Paine MD, Stark JPW, Lee DA ( 2005 ) . Identification and characterization of deposited fibronectin on biocompatible materials: Comparison of electrospray and wetting methods . Proceedings of the 2005 Summer Bioengineering Conference vol. 2005 , 439 - 440 .

Chowdhury TT, Appleby RN, Salter DA, Bader DL, Lee DA ( 2005 ) . Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs . Proceedings of the 2005 Summer Bioengineering Conference vol. 2005 , 545 - 546 .

Bader DL, Lee DA ( 2005 ) . Mechanical conditioning of cell-seeded constructs for soft tissue repair - Are optimisation strategies possible? . 165 - 192 .

Robinson T, Brooker P, Bozak R, Lee DA ( 2005 ) . Integration of photolithographic simulation and a mask repair system into a single concurrent work cell . Proceedings of SPIE--the International Society for Optical Engineering . Conference: 25th Annual BACUS Symposium on Photomask Technology vol. 5992 ,

Robinson T, Dinsdale A, Bozak R, White R, Lee DA, Roessler K ( 2005 ) . Mask repair for the 65-nm technology node . Proceedings of SPIE--the International Society for Optical Engineering . Conference: 25th Annual BACUS Symposium on Photomask Technology vol. 5992 ,

Screen HRC, Shelton JC, Bader DL, Lee DA ( 2005 ) . Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles . Biochem Biophys Res Commun vol. 336 , ( 2 ) 424 - 429 .

Sengers BG, Heywood HK, Lee DA, Oomens CWJ, Bader DL ( 2005 ) . Nutrient utilization by bovine articular chondrocytes: a combined experimental and theoretical approach . J Biomech Eng vol. 127 , ( 5 ) 758 - 766 .

Screen HRC, Shelton JC, Chhaya VH, Kayser MV, Bader DL, Lee DA ( 2005 ) . The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles . Ann Biomed Eng vol. 33 , ( 8 ) 1090 - 1099 .

Chowdhury TT, Bader DL, Lee DA ( 2005 ) . Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs . European Cells and Materials vol. 10 , ( SUPPL.2 )

Catuogno C, Chowdhury TT, Bader DL, Lee DA ( 2005 ) . Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs . European Cells and Materials vol. 10 , ( SUPPL.2 )

Pingguna B, Lee DA, Bader DL, Knight MM ( 2005 ) . Mechanical compression activates chondrocyte Calcium signalling in a cycle dependent Manner Involving the release of ATP . European Cells and Materials . vol. 10 ,

Campbell JJ, Lee DA, Bader DL ( 2005 ) . Mechanical conditioning Influences Mesenchymal stem cell chondrogenesis . European Cells and Materials vol. 10 , ( SUPPL.2 )

Eniwumide JO, Lee DA, Bader DL ( 2005 ) . Perfusion-Enhancement of molecular transport within 3D scaffolds . European Cells and Materials vol. 10 , ( SUPPL.2 )

Heywood HK, Bader DL, Lee DA ( 2005 ) . Superficial and deep chondrocyte subpopulations both express the crabtree effect but exhibit differences in oxygen consumption rate . European Cells and Materials vol. 10 , ( SUPPL.2 )

Brooker P, Robinson T, Lewellen J, Naber B, Bozak R, Lee DA ( 2005 ) . Improved cycle time of mask repair by optimizing nanomachining with photolithographic imaging simulation . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photomask and Next-Generation Lithography Mask Technology XII vol. 5853 , 1009 - 1020 .

Gao J, Lee D, Yang Y, Holdcroft S, Frisken BJ ( 2005 ) . Self-Assembly of Surface-Charged Latex Nanoparticles: A New Route to the Creation of Continuous Channels for Ion Conduction . Macromolecules vol. 38 , ( 14 ) 5854 - 5856 .

Sudre L, Cheung F, Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S et al. ( 2005 ) . British society for matrix biology autumn meeting . International Journal of Experimental Pathology vol. 86 , ( 3 )

Sharma A, Bomzon Z, Lee DA, Kimmel E, Bader DL, Knight MM ( 2005 ) . Compression-induced reorganization of cytoplasmic networks in bovine chondrocytes using mitochondria as markers . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 86 , A34 - A34 .

Screen HRC, Shelton JC, Bader DL, Lee DA ( 2005 ) . Cyclic tensile strain upregulates collagen production in isolated tendon fascicles . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 86 , A8 - A9 .

Heywood HK, Bader DL, Lee DA ( 2005 ) . Glucose metabolism of chondrocytes in tissue-engineered alginate constructs . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 86 , A13 - A14 .

Appleby RN, Chowdhury TT, Salter DM, Bader DL, Lee DA ( 2005 ) . Integrin-mediated mechanotransduction in IL-1 beta-stimulated chondrocytes . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 86 , A38 - A39 .

Baria KE, Bader DL, Screen HRC, Lee DA ( 2005 ) . The effect of substrate and medium composition on the response of human dermal fibroblasts to cyclic tensile strain in vitro . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 86 , A32 - A33 .

Rugg EL, Al-Rawi H, Lee D, McNeill AM ( 2005 ) . Trimethylamine N-oxide reduces the effects of osmotic stress in EBS keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 124 , A76 - A76 .

Lee D, Grant A, Marsden RL, Orengo C ( 2005 ) . Identification and distribution of protein families in 120 completed genomes using Gene3D . Proteins Structure Function and Bioinformatics vol. 59 , ( 3 ) 603 - 615 .

Goldberg AJ, Lee DA, Bader DL, Bentley G ( 2005 ) . Autologous chondrocyte implantation. Culture in a TGF-beta-containing medium enhances the re-expression of a chondrocytic phenotype in passaged human chondrocytes in pellet culture . J Bone Joint Surg Br vol. 87 , ( 1 ) 128 - 134 .

Wang Y-N, Bouten CVC, Lee DA, Bader DL ( 2005 ) . Compression-induced damage in a muscle cell model in vitro . Proc Inst Mech Eng H vol. 219 , ( 1 ) 1 - 12 .

Pearl F, Todd A, Sillitoe I, Dibley M, Redfern O, Lewis T, Bennett C, Marsden R et al. ( 2004 ) . The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis . Nucleic Acids Research vol. 33 , ( suppl_1 ) d247 - d251 .

Dauksher WJ, Nordquist KJ, Le NV, Gehoski KA, Mancini DP, Resnick DJ, Casoose L, Bozak R et al. ( 2004 ) . Repair of step and flash imprint lithography templates . Journal of Vacuum Science & Technology B Nanotechnology and Microelectronics Materials Processing Measurement and Phenomena . vol. 22 , 3306 - 3311 .

Nordquist KJ, Dauksher WJ, Mancini DP, Resnick DJ, Hess HF, Pettibone DW, Adler D, Bertsche K et al. ( 2004 ) . Inspection and repair issues for Step-and-Flash Imprint Lithography templates . Proceedings of SPIE--the International Society for Optical Engineering . Conference: 24th Annual BACUS Symposium on Photomask Technology vol. 5567 ,

Screen HRC, Bader DL, Lee DA, Shelton JC ( 2004 ) . Local strain measurement within tendon . STRAIN vol. 40 , ( 4 ) 157 - 163 .

Bryant SJ, Anseth KS, Lee DA, Bader DL ( 2004 ) . Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain . J Orthop Res vol. 22 , ( 5 ) 1143 - 1149 .

Chowdhury TT, Salter DM, Bader DL, Lee DA ( 2004 ) . Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes . Biochem Biophys Res Commun vol. 318 , ( 4 ) 873 - 881 .

Grant A, Lee D, Orengo C ( 2004 ) . Progress towards mapping the universe of protein folds . Genome Biology vol. 5 , ( 5 )

Lee D ( 2004 ) . Debt crisis looms [10] . Professional Engineering vol. 17 , ( 8 )

Kim B-C, van Gelder H, Kim TA, Lee H-J, Baik KG, Chun HH, Lee DA, Choi KS et al. ( 2004 ) . Activin Receptor-like Kinase-7 Induces Apoptosis through Activation of MAPKs in a Smad3-dependent Mechanism in Hepatoma Cells* . Journal of Biological Chemistry vol. 279 , ( 27 ) 28458 - 28465 .

Bryant SJ, Chowdhury TT, Lee DA, Bader DL, Anseth KS ( 2004 ) . Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels . Ann Biomed Eng vol. 32 , ( 3 ) 407 - 417 .

Lee D, Grant A, Sillitoe I, Dibley M, Ranea JG, Orengo C ( 2004 ) . A structural perspective on genome evolution . Conference: Proceedings of the eighth annual international conference on Computational molecular biology - RECOMB '04336 - 336 .

Screen HRC, Lee DA, Bader DL, Shelton JC ( 2004 ) . An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties . Proc Inst Mech Eng H vol. 218 , ( 2 ) 109 - 119 .

Lee DA, Martin I ( 2004 ) . Bioreactor Culture Techniques for Cartilage-Tissue Engineering . Biopolymer Methods in Tissue Engineering , vol. 238 , Springer Nature

Heywood HK, Sembi PK, Lee DA, Bader DL ( 2004 ) . Cellular utilization determines viability and matrix distribution profiles in chondrocyte-seeded alginate constructs . Tissue Eng vol. 10 , ( 9-10 ) 1467 - 1479 .

Chowdhury TT, Bader DL, LEE DA ( 2004 ) . Combined anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated bovine chondrocytes cultured in agarose constructs . Trans. Orthop. Res. Soc. . Conference: 50th Annual Meeting of the Orthopaedic Research Society vol. 29 , 144 - 144 .

Knight MM, Hibbs K, Roberts SR, LEE DA, Bader DL ( 2004 ) . Cyclic preconditioning mediates chondrocytes calcium signaling in unstrained and compressed agarose constructs . Trans. Orthop. Res. Soc. . Conference: 50th Annual Meeting of the Orthopaedic Research Society vol. 29 , 829 - 829 .

Chowdhury TT, Bader DL, Lee DA ( 2004 ) . Dynamic compression counteracts IL-1 beta-induced iNOS and COX-2 activity in human chondrocytes cultured in agarose constructs . OSTEOARTHRITIS AND CARTILAGE . vol. 12 , S19 - S19 .

LEE DA, van Osch G, Verhaar JAN, Mandl EW, van der Linden JC, van der Breevaart Bravenboer J, Weinans H ( 2004 ) . Extracellular matrix influences the response of chondrocytes to dynamic compression . Trans. Orthop.Rev. Soc vol. 29 , 839 - 839 .

Lee DA, Fefeu S, Edo‐Ukeh AA, Orengo CA, Slingsby C ( 2004 ) . EyeSite: a semi‐automated database of protein families in the eye . Nucleic Acids Research vol. 32 , ( suppl_1 ) d148 - d152 .

Heywood HK, Bader DL, Bongers M, LEE DA ( 2004 ) . Glucose depletion induces an upregulation of oxygen utilisation by chondrocytes . Trans. Orthop. Res. Soc. . Conference: 50th Annual Meeting of the Orthopaedic Research Society vol. 29 , 261 - 261 .

Knight MM, Bonzom Z, Sharma AM, LEE DA, Kimmel E, Bader DL ( 2004 ) . Heterogeneity of deformation of cytoplasmic networks in compressed chondrocytes . Trans. Orthops. Res. Soc. . Conference: 50th Annual Meeting of the Orthopaedic Research Society vol. 29 , 544 - 544 .

Bader DL, KNIGHT MM, Bentley G, Kayser M, Holloway I ( 2004 ) . Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage . Osteoarthritis Cartilage vol. 12 , ( 1 ) 17 - 24 .

Holloway I, Kayser M, Lee DA, Bader DL, Bentley G, Knight MM ( 2004 ) . Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage . Osteoarthritis Cartilage vol. 12 , ( 1 ) 17 - 24 .

Chowdhury TT, Appleby RN, Salter DM, Bader DL, Lee DA ( 2004 ) . Integrin-mediated mechanotransduction in IL-1β stimulated chondrocytes . OSTEOARTHRITIS AND CARTILAGE . vol. 12 , S102 - S102 .

Lee DA, Knight MM ( 2004 ) . Mechanical Loading of Chondrocytes Embedded in 3D Constructs . Cartilage and Osteoarthritis , vol. 100 , Springer Nature

Lee DA, Knight MM ( 2004 ) . Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain . Methods Mol Med vol. 100 , 307 - 324 .

Heywood HK, DeRosa E, LEE DA, Bader DL, Netti P ( 2004 ) . Non-invasive monitoring of molecular diffusion in neo-cartilage using FRAP technique . Trans. Orthop. Res. Soc. . Conference: 50th Annual Meeting of the Orthopaedic Research Society vol. 29 , 531 - 531 .

Wiseman M, Bader DL, Reisler T, Lee DA ( 2004 ) . Passage in monolayer influences the response of chondrocytes to dynamic compression . Biorheology vol. 41 , ( 3-4 ) 283 - 298 .

Chowdhry TT, Salter DM, Bader DL, LEE DA ( 2004 ) . alpha 5 beta 1 integrin mediates mechanotransduction processes in TGF-beta stimulated human chondrocytes seeded in agarose constructs and subjected to dynamic compression . Trans. Orthop. Res. Soc. . Conference: 50th Annual Meeting of the Orthopaedic Research Society vol. 29 , 338 - 338 .

Chowdhury TT, Bader DL, Lee DA ( 2003 ) . Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs . Osteoarthritis Cartilage vol. 11 , ( 9 ) 688 - 696 .

Chowdhury TT, Bader DL, Shelton JC, Lee DA ( 2003 ) . Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression . Arch Biochem Biophys vol. 417 , ( 1 ) 105 - 111 .

Berry CC, Shelton JC, Bader DL, Lee DA ( 2003 ) . Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels . Tissue Eng vol. 9 , ( 4 ) 613 - 624 .

Wiseman M, Henson F, Lee DA, Bader DL ( 2003 ) . Dynamic compressive strain inhibits nitric oxide synthesis by equine chondrocytes isolated from different areas of the cartilage surface . Equine Vet J vol. 35 , ( 5 ) 451 - 456 .

Lee D, Grant A, Buchan D, Orengo C ( 2003 ) . A structural perspective on genome evolution . Current Opinion in Structural Biology vol. 13 , ( 3 ) 359 - 369 .

Knight MM, Roberts SR, Lee DA, Bader DL ( 2003 ) . Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death . American Journal of Physiology - Cell Physiology . vol. 284 ,

Knight MM, Roberts SR, Lee DA, Bader DL ( 2003 ) . Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death . Am J Physiol Cell Physiol vol. 284 , ( 4 ) C1083 - C1089 .

Lee DA, Reisler T, Bader DL ( 2003 ) . Expansion of chondrocytes for tissue engineering in alginate beads enhances chondrocytic phenotype compared to conventional monolayer techniques . Acta Orthop Scand vol. 74 , ( 1 ) 6 - 15 .

Chowdhury TT, Shelton JC, Bader DL, LEE DA ( 2003 ) . Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs . Internat. J. Artificial Organs vol. 26 , ( 9 ) 858 - 858 .

Berry CC, Cacou C, Lee DA, Bader DL, Shelton JC ( 2003 ) . Dermal fibroblasts respond to mechanical conditioning in a strain profile dependent manner . Biorheology vol. 40 , ( 1-3 ) 337 - 345 .

Screen HRC, Lee DA, Bader DL, Shelton JC ( 2003 ) . Development of a technique to determine strains in tendons using the cell nuclei . Biorheology vol. 40 , ( 1-3 ) 361 - 368 .

LEE DA, Heywood HK, Baaijens FPT, Oomens CWJ, Sengers BG ( 2003 ) . Experimental and theoretical analysis of glucose dependent oxygen utilization by bovine articular chondrocytes . Internat. J. Artificial Organs vol. 26 , 875 - 875 .

Shelton JC, Bader DL, Lee DA ( 2003 ) . Mechanical conditioning influences the metabolic response of cell-seeded constructs . Cells Tissues Organs vol. 175 , ( 3 ) 140 - 150 .

SCREEN HRC, Shelton JC, Bader DL, Lee DA ( 2003 ) . The effects on non-collagenous matrix components on tendon fascicle micromechanics . Trans. Orthop. Res. Soc. . Conference: 49th Annual Meeting of the Orthopaedic Research Society vol. 28 , 806 - 806 .

Hernandez D, Addou S, Lee D, Orengo C, Shephard EA, Phillips IR ( 2003 ) . Trimethylaminuria and a human FMO3 mutation database . HUM MUTAT vol. 22 , ( 3 ) 209 - 213 .

Chowdhury TT, LEE DA, Salter DM, Shelton JC, Bader DL ( 2003 ) . alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression . Osteoarthritis Cartilage vol. 11 , ( Suppl 1 ) S2 - S3 .

Chowdhury TT, LEE DA, Salter DM, Shelton JC, Bader DL ( 2003 ) . alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta3-stimulated human chondrocytes seeded in agarose constructs and subjected to dynamic compression . Tissue Engineering . Conference: ETES vol. 9 , 792 - 792 .

Knight MM, Roberts SR, Lee DA, Bader DL ( 2002 ) . Light-induced calcium signalling in chondrocytes . European Cells and Materials . vol. 4 , 7 - 8 .

Knight MM, Toyoda T, Bader DL, Lee DA ( 2002 ) . Mechanical strain and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose . Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products .

Lee DA ( 2002 ) . The design of bioreactor systems for cartilage tissue engineering . Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products

Berry CC, Shelton JC, Bader DL, Lee DA ( 2002 ) . The influence of uniaxial cyclic strain on orientated fibroblast seeded collagen gels . Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products

Lee DA, Chowdhury TT, Roberts SR, Knight MM, Bader DL ( 2002 ) . An in vitro investigation of cartilage mechanotransduction . INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS . vol. 25 , 617 - 618 .

Lee D, Allington‐Smith JR ( 2002 ) . An experimental investigation of immersed gratings . Monthly Notices of the Royal Astronomical Society vol. 312 , ( 1 ) 57 - 69 .

Lee D, Haynes R, Skeen DJ ( 2002 ) . Properties of optical fibres at cryogenic temperatures . Monthly Notices of the Royal Astronomical Society vol. 326 , ( 2 ) 774 - 780 .

Ziegler BL, Bower RG, Smail I, Davies RL, Lee D ( 2002 ) . The early‐type galaxy population in Abell 2218 . Monthly Notices of the Royal Astronomical Society vol. 325 , ( 4 ) 1571 - 1590 .

Turner JEH, Allington‐Smith J, Chapman S, Content R, Done C, Haynes R, Lee D, Morris S ( 2002 ) . The origin of [Fe ii] emission in NGC 4151 . Monthly Notices of the Royal Astronomical Society vol. 331 , ( 2 ) 284 - 292 .

Knight MM, van de Breevaart Bravenboer J, Lee DA, van Osch GJVM, Weinans H, Bader DL ( 2002 ) . Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus . Biochim Biophys Acta vol. 1570 , ( 1 ) 1 - 8 .

Orengo CA, Bray JE, Buchan DWA, Harrison A, Lee D, Pearl FMG, Sillitoe I, Todd AE et al. ( 2002 ) . The CATH protein family database: A resource for structural and functional annotation of genomes . Proteomics . vol. 2 , 11 - 21 .

Holloway I, Knight MM, LEE DA, Bader DL, Bentley G ( 2002 ) . Changes in cell morphology and cytoskeletal organisation in osteoarthritic cartilage . Eur Cell Mater . Conference: ECM III Cartilage & Joint repair Tutorials, Basic Research & Clinical Methods ( Davos, Switzerland ) from: 01/07/2002 to: 03/07/2002 , vol. 4 suppl 1 , 52 - 53 .

Holloway I, Knight MM, LEE DA, Bader DL, Bentley G ( 2002 ) . Characterisation of cell morphology, cytoskeletal organization and apoptosis in human osteoarthritic cartilage . Trans. Orthop. Res. Soc . Conference: 48th Annual Meeting of the Orthopaedic Research Society vol. 27 ,

Bader DL, Ohashi T, Knight MM, Lee DA, Sato M ( 2002 ) . Deformation properties of articular chondrocytes: a critique of three separate techniques . Biorheology . vol. 39 , 69 - 78 .

BADER DL, Shelton JC, Lee DA, Screen HRC ( 2002 ) . Development of a technique to determine strains in tendons using the cell nuclei . Biorheology vol. 40 , 361 - 368 .

Knight MM, Roberts SR, LEE DA, Bader DL ( 2002 ) . Light-induced calcium signalling in chondrocytes . Eur. Cells Materials . Conference: TCES 2002 Annual meeting of the UK Tissue and Cell Engineering Society ( University of Glasgow, Scotland ) from: 19/09/2002 to: 20/09/2002 , vol. 4 , 7 - 8 .

Knight MM, Toyoda T, LEE DA, Bader DL ( 2002 ) . Mechanical strain and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose . Trans. Orthop. Res. Soc. . Conference: 48th Annual Meeting of the Orthopaedic Research Society vol. 27 , 35 - 35 .

Heywood HK, LEE DA, Bader DL ( 2002 ) . Monitoring neo-cartilage formation in cell seeded alginate constructs of clinically relevant dimensions . Eur. Cells Materials . Conference: TCES 2002 Annual meeting of the UK Tissue and Cell Engineering Society ( Glasgow, Scotland ) from: 19/09/2002 to: 20/09/2002 , vol. 4 suppl 2 , 1 - 2 .

Bader DL, Shelton JC, Lee DA, SCREEN HRC ( 2002 ) . Non-collagenous matrix components influence the micromechanical environment of tenocytes within tendon fascicles subjected to tensile strain . Eur. Cells Mat. vol. 4:S1 , 41 - 42 .

SCREEN HRC, Lee DA, Bader DL, Shelton JC ( 2002 ) . The strain behaviour of tendon under tensile load, using cell nuclei as strain markers . Trans. Orthop. Res. Soc. . Conference: 48th Annual Meeting of the Orthopaedic Research Society vol. 27 , 604 - 604 .

Lee D, Haynes R, Ren D, Allington‐Smith J ( 2001 ) . Characterization of Lenslet Arrays for Astronomical Spectroscopy . Publications of the Astronomical Society of the Pacific vol. 113 , ( 789 ) 1406 - 1419 .

Bader D, Lee D ( 2001 ) . Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine (2000) Edited by Johnny Huard and Freddie H. Fu, ISBN 0-8176-4071-1, Birkhauser: Boston pages 1–286 . Medical Engineering & Physics vol. 23 , ( 8 )

Chowdhury TT, Bader DL, Lee DA ( 2001 ) . Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1beta-stimulated chondrocytes cultured in agarose constructs . Biochem Biophys Res Commun vol. 285 , ( 5 ) 1168 - 1174 .

Antonyak MA, Singh US, Lee DA, Boehm JE, Combs C, Zgola MM, Page RL, Cerione RA ( 2001 ) . Effects of Tissue Transglutaminase on Retinoic Acid-induced Cellular Differentiation and Protection against Apoptosis* . Journal of Biological Chemistry vol. 276 , ( 36 ) 33582 - 33587 .

Knight MM, Ross JM, Sherwin AF, Lee DA, Bader DL, Poole CA ( 2001 ) . Chondrocyte deformation within mechanically and enzymatically extracted chondrons compressed in agarose . Biochim Biophys Acta vol. 1526 , ( 2 ) 141 - 146 .

Knight MM, Idowu BD, Lee DA, Bader DL ( 2001 ) . Temporal changes in cytoskeletal organisation within isolated chondrocytes quantified using a novel image analysis technique . Med Biol Eng Comput vol. 39 , ( 3 ) 397 - 404 .

Roberts SR, Knight MM, Lee DA, Bader DL ( 2001 ) . Mechanical compression influences intracellular Ca2+ signaling in chondrocytes seeded in agarose constructs . J Appl Physiol (1985) vol. 90 , ( 4 ) 1385 - 1391 .

Bouten CV, Knight MM, Lee DA, Bade DL ( 2001 ) . Compressive deformation and damage of muscle cell subpopulations in a model system . Ann Biomed Eng vol. 29 , ( 2 ) 153 - 163 .

Pearl FM, Martin N, Bray JE, Buchan DW, Harrison AP, Lee D, Reeves GA, Shepherd AJ et al. ( 2001 ) . A rapid classification protocol for the CATH Domain Database to support structural genomics . Nucleic Acids Research vol. 29 , ( 1 ) 223 - 227 .

Bader DL, KNIGHT MM, Lee DA, Bouten CV ( 2001 ) . Compressive deformation and damage of muscle cell subpopulaltions in a model system . Ann. Biomed. Eng. vol. 29 , ( 2 ) 153 - 163 .

Chowdhury T, Bader DL, LEE DA ( 2001 ) . Dynamic compression influences the synthesis of nitric oxide by IL-1beta stimulated chondrocyte sub-populations cultured in agarose constructs . Trans. Orthop. Res. Soc . Conference: 47th Annual Meeting, Orthopaedic Research Society ( San Francisco, California ) from: 25/02/2001 to: 28/02/2001 , vol. 26 , 604 - 604 .

Lee DA ( 2001 ) . Embryonic stem cells: scientific possibilities, ethical considerations, and regulation in the UK . INTERDISCIPL SCI REV vol. 26 , ( 2 ) 112 - 124 .

LEE DA, Idowu BD, Knight MM, Bader DL ( 2001 ) . Mechanical compression influences cytoskeletal oragnisation within chondrocytes seeded in agarose constructs . Trans. Orthop. Res. Soc. . Conference: 47th Annual Meeting, Orthopaedic Research Society ( San Francisco, California ) from: 25/02/2001 to: 28/02/2001 , vol. 26 , 263 - 263 .

Enobakhare B, Bader DL, LEE DA ( 2001 ) . Physiochemical, biochemical and mechanical characterisation of chondrocyte-alginate constructs . Trans. Orthop. Res. Soc . Conference: 47th Annual Meeting, Orthopaedic Research Society ( San Francisco, California ) from: 25/02/2001 to: 28/02/2001 , vol. 26 , 638 - 638 .

Knight MM, van de Breevaart Brevenboer J, van Osch G, Weinans H, LEE DA, Bader DL ( 2001 ) . Temporal changes in cell and nucleus deformation in isolated chondrocytes compressed in alginate scaffolds . Trans. Orthop. Res. Soc. . Conference: 47th Annual Meeting, Orthopaedic Research Society ( San Francisco, California ) from: 25/02/2001 to: 28/02/2001 , vol. 26 , 611 - 611 .

Albà MM, Lee D, Pearl FMG, Shepherd AJ, Martin N, Orengo CA, Kellam P ( 2001 ) . VIDA: a virus database system for the organization of animal virus genome open reading frames . Nucleic Acids Research vol. 29 , ( 1 ) 133 - 136 .

Haynes R, Baldry IK, Taylor K, Lee D ( 2000 ) . Characterisation of cooled infrared fibres for the Gemini IRMOS . Proceedings of SPIE - The International Society for Optical Engineering . vol. 4008 ,

Lee D, Taylor K ( 2000 ) . Fibre developments at the Anglo-Australian Observatory for SPIRAL and AUSTRALIS . Proceedings of SPIE - The International Society for Optical Engineering . vol. 4008 ,

Berry CC, Cacou C, Shelton JC, Bader DL, Lee DA ( 2000 ) . Biological response of cyclic strain on developed cell seeded collagen gel model . Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling

Knight MM, Van De Breevaart Bravenboer J, Bader DL, Lee DA ( 2000 ) . Compression induced cell and nucleus deformation in chondrocyte-alginate constructs . Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling .

Chowdhury TT, Bader DL, Lee DA ( 2000 ) . Dynamic compression inhibits the synthesis of nitric oxide by IL-1β stimulated chondrocytes cultured in agarose constructs . Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling

Roberts SR, Knight MM, Lee DA, Bader DL ( 2000 ) . Intracellular - CA2+ signalling in compressed chondrocyte agarose constructs . Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling .

Enobakhare BO, Bader DL, Lee DA ( 2000 ) . Physiochemical, biochemical and mechanical characterisation of chondrocyte-alginate constructs . Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling

Cacou C, Palmer D, Lee DA, Bader DL, Shelton JC ( 2000 ) . A system for monitoring the response of uniaxial strain on cell seeded collagen gels . MED ENG PHYS vol. 22 , ( 5 ) 327 - 333 .

Idowu BD, Knight MM, Bader DL, Lee DA ( 2000 ) . Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose . Histochem J vol. 32 , ( 3 ) 165 - 174 .

Roberts SR, Knight MM, Lee DA, Bader DL ( 2000 ) . Intracellular calcium signalling in compressed chondrocyte agarose constructs . J PHYSIOL-LONDON . vol. 523 , 12P - 12P .

Pearl FM, Lee D, Bray JE, Sillitoe I, Todd AE, Harrison AP, Thornton JM, Orengo CA ( 2000 ) . Assigning genomic sequences to CATH . Nucleic Acids Research vol. 28 , ( 1 ) 277 - 282 .

Bader D, Lee D ( 2000 ) . Chapter 4 Structure – Properties of Soft Tissues Articular Cartilage . Structural Biological Materials - Design and Structure-Property Relationships , vol. 4 , Elsevier

Lee DA, Knight MM, Bolton JF, Idowu BD, Kayser MV, Bader DL ( 2000 ) . Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels . J Biomech vol. 33 , ( 1 ) 81 - 95 .

Lee DA, Noguchi T, Frean SP, Lees P, Bader DL ( 2000 ) . The influence of mechanical loading on isolated chondrocytes seeded in agarose constructs . Biorheology vol. 37 , ( 1-2 ) 149 - 161 .

Kang SH, Bang Y-J, Im Y-H, Yang H-K, Lee DA, Lee HY, Lee HS, Kim NK et al. ( 1999 ) . Transcriptional repression of the transforming growth factor-β type I receptor gene by DNA methylation results in the development of TGF-β resistance in human gastric cancer . Oncogene vol. 18 , ( 51 ) 7280 - 7286 .

Lee DA ( 1999 ) . Models of government regulation of privatized transit systems in five Latin American cities . Transportation Quarterly vol. 53 , ( 1 ) 21 - 39 .

Haynes R, Lee D, Allington‐Smith J, Content R, Dodsworth G, Lewis I, Sharples R, Turner J et al. ( 1999 ) . Multiple‐Object and Integral Field Near‐Infrared Spectroscopy Using Fibers . Publications of the Astronomical Society of the Pacific vol. 111 , ( 765 ) 1451 - 1468 .

White AET, Bentley G, Stephens MD, Bader DL, Giddins GEB, Lee DA ( 1999 ) . The effects of storage temperature on the composition, metabolism acid biomechanical properties of human articular cartilage . KNEE vol. 6 , ( 3 ) 197 - 205 .

Lee DA ( 1999 ) . Introducing Fare Simplification and New Convenience Fares at Connecticut Transit . Transportation Research Record Journal of the Transportation Research Board vol. 1669 , ( 1 ) 109 - 112 .

O'Neil C, Lee D, Clewley G, Johnson MA, Emery VC ( 1998 ) . Prevalence of anti‐Vif antibodies in HIV‐1 infected individuals assessed using recombinant baculovirus expressed Vif protein . Journal of Medical Virology vol. 51 , ( 3 ) 139 - 144 .

Lao WC, Lee D, Burroughs AK, Lanzini G, Rolles K, Emery VC, Griffiths PD ( 1998 ) . Use of polymerase chain reaction to provide prognostic information on human cytomegalovirus disease after liver transplantation . Journal of Medical Virology vol. 51 , ( 3 ) 152 - 158 .

Haynes R, Doei AP, Content R, Allington-Smith J, Lee D ( 1998 ) . TEIFU: A thousand element integral field unit for the WHT fed by the ELECTRA AO system . Proceedings of SPIE - The International Society for Optical Engineering . vol. 3355 , 786 - 797 .

Lee DA, Noguchi T, Knight MM, O'Donnell L, Bentley G, Bader DL ( 1998 ) . Response of chondrocyte subpopulations cultured within unloaded and loaded agarose . J Orthop Res vol. 16 , ( 6 ) 726 - 733 .

Knight MM, Lee DA, Bader DL ( 1998 ) . The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose . Biochim Biophys Acta vol. 1405 , ( 1-3 ) 67 - 77 .

Lee DA, Frean SP, Lees P, Bader DL ( 1998 ) . Dynamic mechanical compression influences nitric oxide production by articular chondrocytes seeded in agarose . BIOCHEM BIOPH RES CO vol. 251 , ( 2 ) 580 - 585 .

Haynes R, Content R, Turner JE, Allington-Smith JR, Lee D ( 1998 ) . SMIRFS-II: multiobject and integral-field near-IR spectroscopy at UKIRT . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Infrared Astronomical Instrumentation vol. 3354 , 419 - 430 .

Lee D, Allington-Smith JR, Content R, Haynes R ( 1998 ) . Characterization of microlens arrays for integral field spectroscopy . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Optical Astronomical Instrumentation vol. 3355 , 810 - 820 .

Murowinski RG, Bond T, Crampton D, Davidge TJ, Fletcher JM, Leckie B, Morbey CL, Roberts SC et al. ( 1998 ) . Gemini multiobject spectrographs . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Optical Astronomical Instrumentation vol. 3355 , 188 - 195 .

Lee DA, Goodfellow JM ( 1998 ) . The pH-Induced Release of Iron from Transferrin Investigated with a Continuum Electrostatic Model . Biophysical Journal vol. 74 , ( 6 ) 2747 - 2759 .

Lee DA, Assoku E, Doyle V ( 1998 ) . A specific quantitative assay for collagen synthesis by cells seeded in collagen-based biomaterials using sirius red F3B precipitation . J MATER SCI-MATER M vol. 9 , ( 1 ) 47 - 51 .

Lao WC, Lee D, Burroughs AK, Lanzani G, Rolles K, Emery VC, Griffiths PD ( 1998 ) . Erratum: Use of polymerase chain reaction to provide prognostic information on human cytomegalovirus disease after liver transplantation. (Journal of Medical Virology 51 (152-158)) . Journal of Medical Virology vol. 54 , ( 1 )

Knight MM, Ghori SA, Lee DA, Bader DL ( 1998 ) . Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression . Med Eng Phys vol. 20 , ( 9 ) 684 - 688 .

Davies RL, Allington-Smith JR, Bettess P, Chadwick E, Content R, Dodsworth GN, Haynes R, Lee D et al. ( 1997 ) . GMOS: the GEMINI Multiple Object Spectrographs . Proceedings of SPIE - The International Society for Optical Engineering . vol. 2871 , 1099 - 1106 .

Lee DA, Salih V, Stockton EF, Stanton JS, Bentley G ( 1997 ) . Effect of Normal Synovial Fluid on the Metabolism of Articular Chondrocytes In Vitro . Clinical Orthopaedics and Related Research® vol. 342 , ( &NA; ) 228 - 238 .

Lee DA, Bader DL ( 1997 ) . Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose . J ORTHOP RES vol. 15 , ( 2 ) 181 - 188 .

Lee DA ( 1997 ) . Frame conflicts and competing construals in family argument . Journal of Pragmatics vol. 27 , ( 3 ) 339 - 360 .

( 1996 ) . Preliminary Results From the Cancer Research Campaign Trial Evaluating Tamoxifen Duration in Women Aged Fifty Years or Older With Breast Cancer . Journal of the National Cancer Institute vol. 88 , ( 24 ) 1834 - 1839 .

Pearson RG, Lee DA, Doyle V, Bader DL ( 1996 ) . Cellular responses to poly-L-lactic acid degradation products . Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium . vol. 1 ,

Gor D, Lee D, Emery VC ( 1996 ) . J. Virol. Methods Erratum to “Detection of human cytomegalovirus polymerase chain reaction products using oligonucleotide probes directly conjugated to alkaline phosphatase” [61 (1996) 145] . Journal of Virological Methods vol. 62 , ( 2 )

Lee DA, Bader DL ( 1996 ) . Mechanical strain influences the metabolism of chondrocytes cultured in an artificial matrix . Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium . vol. 1 ,

Enobakhare B, Bader D, Lee DA ( 1996 ) . Novel system for the production of chondrocyte seeded alginate constructs . Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium . vol. 1 ,

Enobakhare BO, Bader DL, Lee DA ( 1996 ) . Quantification of sulfated glycosaminoglycans in chondrocyte/alginate cultures, by use of 1,9-dimethylmethylene blue . ANAL BIOCHEM vol. 243 , ( 1 ) 189 - 191 .

Johnson SC, Rovinsky RB, Chin DK, Kostiuk PF, Lee DA, Hemm RV, Wingrove ER ( 1996 ) . Reduction of weather-related terminal area delays in the free-flight era . AIAA/IEEE Digital Avionics Systems Conference - Proceedings . 185 - 190 .

Doyle V, Pearson RG, Lee DA ( 1996 ) . Specific quantitative assay to determine the rate of collagen synthesis in a collagen gel system . Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium . vol. 2 ,

Gor D, Lee D, Emery VC ( 1996 ) . Detection of human cytomegalovirus polymerase chain reaction products using oligonucleotide probes directly conjugated to alkaline phosphatase . Journal of Virological Methods vol. 61 , ( 1-2 ) 145 - 150 .

Doyle V, Pearson R, Lee D, Wolowacz S, Mc Taggart S ( 1996 ) . An investigation of the growth of human dermal fibroblasts on poly-L-lactic acid in vitro . Journal of Materials Science: Materials in Medicine vol. 7 , ( 6 ) 381 - 385 .

Gorinsky B, Laskowski RA, Lee DA, Bomford A ( 1996 ) . Conformational analysis of pentapeptide sequences matching a proposed recognition motif for lysosomal degradation . Biochimica et Biophysica Acta vol. 1293 , ( 2 ) 243 - 253 .

Lee D, Sanders M ( 1996 ) . Implementing a Visioning and Strategic Planning Process at CTTransit . Transportation Research Record Journal of the Transportation Research Board vol. 1521 , 58 - 61 .

Lee DA, Bader DL ( 1995 ) . The development and characterization of an in vitro system to study strain-induced cell deformation in isolated chondrocytes . IN VITRO CELL DEV-AN vol. 31 , ( 11 ) 828 - 835 .

Lee D, Recce M ( 1994 ) . Quantitative evaluation of the exploration strategies of a mobile robot . Proceedings of the National Conference on Artificial Intelligence . vol. 2 ,

Lee D, Recce M ( 1994 ) . Quantitative evaluation of the exploration strategies of an intelligent vehicle . Intelligent Vehicles Symposium, Proceedings . 538 - 543 .

Lee DA, Bentley G, Archer CW ( 1994 ) . Proteoglycan depletion alone is not sufficient to stimulate proteoglycan synthesis in cultured bovine cartilage explants . Osteoarthritis and Cartilage vol. 2 , ( 3 ) 175 - 185 .

Reissis N, Downes S, Kayser M, Lee D, Bentley G ( 1994 ) . Characterization of the repair tissue in articular cartilage defects using silver-enhanced colloidal gold immunostaining . Journal of Materials Science: Materials in Medicine vol. 5 , ( 6-7 ) 402 - 406 .

Lee DA, Bentley G, Archer CW ( 1993 ) . The control of cell division in articular chondrocytes . Osteoarthritis and Cartilage vol. 1 , ( 2 ) 137 - 145 .

Lee DA ( 1991 ) . Categories in the description of just . Lingua vol. 83 , ( 1 ) 43 - 66 .

Archer CW, Cottrill CP, Lee D ( 1990 ) . Effects of ascorbate on myogenesis in micromass culture . In Vitro Cellular & Developmental Biology vol. 26 , ( 3 ) 259 - 264 .

Lee DA ( 1990 ) . Digitization of the AT&T worldwide intelligent network . AT&T technology vol. 5 , ( 1 ) 14 - 19 .

Haupert D, Chen FG, Lee D ( 1989 ) . VLSI package reliability risk due to accelerated environmental testing .

Jones BM, Evans PM, Lee DA ( 1989 ) . Relation between the rate of cell movement under agarose and the positioning of cells in heterotypic aggregates . Experimental Cell Research vol. 180 , ( 1 ) 287 - 296 .

Lee D ( 1988 ) . INTEGRATED SERVICES DIGITAL NETWORK . British Telecommunications Engineering vol. 7 , ( pt 2 ) 2 - 12 .

Lee DA ( 1988 ) . Moth Density and Oviposition Patterns of the European Corn Borer, Ostrinia nubilalis (Lepidoptera: Pyralidae), in Alberta . Environmental Entomology vol. 17 , ( 2 ) 220 - 224 .

Lee DA, Spence JR ( 1987 ) . Reproductive patterns of the European corn borer (Ostrinia nubilalis) in Alberta . Canadian Journal of Zoology vol. 65 , ( 7 ) 1733 - 1740 .

Lee D ( 1987 ) . The semantics of just . Journal of Pragmatics vol. 11 , ( 3 ) 377 - 398 .

Lee DA ( 1985 ) . MECHANICAL CONVEYING SELECTION CONSIDERATIONS . Proceedings of the Technical Program - Powder & Bulk Solids Conference/Exhibition . 435 - 441 .

Lee DA ( 1984 ) . GUIDELINES FOR SELECTING PNEUMATIC CONVEYING SYSTEMS . Proceedings of the Technical Program - International Powder and Bulk Solids Handling and Processin . 95 - 106 .

Lee DA, Winslow NR, Speight AN, Hey EN ( 1983 ) . Prevalence and spectrum of asthma in childhood . The BMJ vol. 286 , ( 6373 )

Speight AN, Lee DA, Hey EN ( 1983 ) . Underdiagnosis and undertreatment of asthma in childhood . The BMJ vol. 286 , ( 6373 )

Angelini P, Bond WD, Caputo AJ, Mack JE, Lackey WJ, Lee DA, Stinton DP ( 1981 ) . Sol-Gel Technology Applied to Crystalline Ceramic Nuclear Waste Forms . 173 - 180 .