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Research

Publications: Prof Yongjie Lu

Gao J-H, He A-D, Liu L-M, Zhou Y-J, Guo Y-W, Lu M, Zeng X-B, Gong X et al. ( 2024 ) . Direct interaction of platelet with tumor cell aggravates hepatocellular carcinoma metastasis by activating TLR4/ADAM10/CX3cl1 axis . Cancer Letters vol. 585 ,
Watts EL, Gonzales TI, Strain T, Saint-Maurice PF, Bishop DT, Chanock SJ, Johansson M, Keku TO et al. ( 2023 ) . Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study . British Journal of Cancer vol. 130 , ( 1 ) 114 - 124 .
Wang A, Shen J, Rodriguez AA, Saunders EJ, Chen F, Janivara R, Darst BF, Sheng X et al. ( 2023 ) . Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants . Nature Genetics vol. 55 , ( 12 ) 2065 - 2074 .
Al-Hammouri T, Almeida-Magana R, Lawrence R, Duffy T, White L, Burke E, Kudahetti S, Collins J et al. ( 2023 ) . Protocol for a prospective study evaluating circulating tumour cells status to predict radical prostatectomy treatment failure in localised prostate cancer patients (C-ProMeta-1) . BMC Cancer vol. 23 , ( 1 )
Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T et al. ( 2023 ) . Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry . American Journal of Human Genetics vol. 110 , ( 7 ) 1200 - 1206 .
Lawrence R, Watters M, Davies CR, Pantel K, Lu Y-J ( 2023 ) . Circulating tumour cells for early detection of clinically relevant cancer . Nature Reviews Clinical Oncology vol. 20 , ( 7 ) 487 - 500 .
Yarmolinsky J, Bouras E, Constantinescu A, Burrows K, Bull CJ, Vincent EE, Martin RM, Dimopoulou O et al. ( 2023 ) . Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis . Diabetologia vol. 66 , ( 8 ) 1481 - 1500 .
Davies CR, Guo T, Burke E, Stankiewicz E, Xu L, Mao X, Scandura G, Rajan P et al. ( 2023 ) . The potential of using circulating tumour cells and their gene expression to predict docetaxel response in metastatic prostate cancer . Frontiers in Oncology vol. 12 ,
Zhang Y, Wang K, Yang D, Liu F, Xu X, Feng Y, Wang Y, Zhu S et al. ( 2022 ) . Hsa_circ_0094606 promotes malignant progression of prostate cancer by inducing M2 polarization of macrophages through PRMT1-mediated arginine methylation of ILF3 . Carcinogenesis vol. 44 , ( 1 ) 15 - 28 .
Chang Q, Chen P, Yin J, Liang G, Dai Y, Guan Y, Chen Y, Zhao Y et al. ( 2022 ) . Discovery and validation of bladder cancer related excreted nucleosides biomarkers by dilution approach in cell culture supernatant and urine using UHPLC-MS/MS . Journal of Proteomics vol. 270 ,
Buhigas C, Warren AY, Leung W-K, Whitaker HC, Luxton HJ, Hawkins S, Kay J, Butler A et al. ( 2022 ) . The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates . Molecular Cancer vol. 21 , ( 1 )
Burns D, Anokian E, Saunders EJ, Bristow RG, Fraser M, Reimand J, Schlomm T, Sauter G et al. ( 2022 ) . Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study . European Urology vol. 82 , ( 2 ) 201 - 211 .
Xue X, Dong L, Burke E, Xue L, Lu Y-J ( 2022 ) . The interaction of p53 and DNA repair gene mutations and their impact on tumor mutation burden and immune response in human malignancies . American Journal of Cancer Research vol. 12 , ( 4 ) 1866 - 1883 .
Berstein FM, McCartney DL, Lu AT, Tsilidis KK, Bouras E, Haycock P, Burrows K, Phipps AI et al. ( 2022 ) . Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study . eLife vol. 11 ,
Zhang Y, Hollis D, Ross R, Snow T, Terrill NJ, Lu Y, Wang W, Connelly J et al. ( 2022 ) . Investigating the Fibrillar Ultrastructure and Mechanics in Keloid Scars Using In Situ Synchrotron X-ray Nanomechanical Imaging . Materials (Basel) vol. 15 , ( 5 )
Huynh-Le M-P, Karunamuni R, Fan CC, Asona L, Thompson WK, Martinez ME, Eeles RA, Kote-Jarai Z et al. ( 2022 ) . Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score . Prostate Cancer and Prostatic Diseases vol. 25 , ( 4 ) 755 - 761 .
Guo Y, Yin J, Dai Y, Guan Y, Chen P, Chen Y, Huang C, Lu Y-J et al. ( 2021 ) . A Novel CpG Methylation Risk Indicator for Predicting Prognosis in Bladder Cancer . Frontiers in Cell and Developmental Biology vol. 9 ,
Martin K, Zhang T, Lin T-T, Habowski AN, Zhao R, Tsai C-F, Chrisler WB, Sontag RL et al. ( 2021 ) . Facile One-Pot Nanoproteomics for Label-Free Proteome Profiling of 50–1000 Mammalian Cells . Journal of Proteome Research vol. 20 , ( 9 ) 4452 - 4461 .
Huynh-Le M-P, Fan CC, Karunamuni R, Thompson WK, Martinez ME, Eeles RA, Kote-Jarai Z, Muir K et al. ( 2021 ) . Polygenic hazard score is associated with prostate cancer in multi-ethnic populations . Nature Communications vol. 12 , ( 1 )
Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA et al. ( 2021 ) . Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction . Nature Genetics vol. 53 , ( 3 ) 413 - 413 .
Marzec J, Ross-Adams H, Pirrò S, Wang J, Zhu Y, Mao X, Gadaleta E, Ahmad AS et al. ( 2021 ) . The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis . Cancers vol. 13 , ( 2 )
Guo T, Wang Y, Jia J, Mao X, Stankiewicz E, Scandura G, Burke E, Xu L et al. ( 2021 ) . The Identification of Plasma Exosomal miR-423-3p as a Potential Predictive Biomarker for Prostate Cancer Castration-Resistance Development by Plasma Exosomal miRNA Sequencing . Frontiers in Cell and Developmental Biology vol. 8 ,
Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA et al. ( 2021 ) . Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction . Nature Genetics vol. 53 , ( 1 ) 65 - 75 .
Bailey MH, Meyerson WU, Dursi LJ, Wang L-B, Dong G, Liang W-W, Weerasinghe A, Li S et al. ( 2020 ) . Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples . Nature Communications vol. 11 , ( 1 )
Bailey MH, Meyerson WU, Dursi LJ, Wang L-B, Dong G, Liang W-W, Weerasinghe A, Li S et al. ( 2020 ) . Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples . Nature Communications vol. 11 , ( 1 )
Li CH, Prokopec SD, Sun RX, Yousif F, Schmitz N, Boutros PC ( 2020 ) . Sex differences in oncogenic mutational processes . Nature Communications vol. 11 , ( 1 )
Wu L, Yang Y, Guo X, Shu X-O, Cai Q, Shu X, Li B, Tao R et al. ( 2020 ) . An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk . Nature Communications vol. 11 , ( 1 )
Tilley W, Risbridger GP, Clements J, Horvath L, Taylor R, Hayes V, Butler L, Yeadon T et al. ( 2020 ) . Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan . Nature Communications vol. 11 , ( 1 )
( 2020 ) . Pan-cancer analysis of whole genomes . Nature vol. 578 , ( 7793 ) 82 - 93 .
Xu L, Mao X, Grey A, Scandura G, Guo T, Burke E, Marzec J, Abdu S et al. ( 2020 ) . Reply by Authors . The Journal of urology vol. 203 , ( 1 ) 81 - 82 .
Stankiewicz E, Guo T, Mao X, Lu YJ ( 2019 ) . Fluorescence in situ hybridization and rehybridization using bacterial artificial chromosome probes . Methods in Molecular Biology vol. 2054 , 243 - 261 .
Guo T, Stankiewicz E, Mao X, Lu YJ ( 2019 ) . The isolation and analysis of circulating tumor cells . Methods in Molecular Biology vol. 2054 , 115 - 128 .
Xu L, Mao X, Grey A, Scandura G, Guo T, Burke E, Marzec J, Abdu S et al. ( 2019 ) . Noninvasive Detection of Clinically Significant Prostate Cancer Using Circulating Tumor Cells . The Journal of Urology vol. 203 , 101097JU000000000000 - 101097JU000000000000 .
Loveday C, Sud A, Litchfield K, Levy M, Holroyd A, Broderick P, Kote‐Jarai Z, Dunning AM et al. ( 2019 ) . Runs of homozygosity and testicular cancer risk . Andrology vol. 7 , ( 4 ) 555 - 564 .
Guo T, Wang Y, Mao X, Xu L, Marzec J, Burke E, Scandura G, Stankiewicz E et al. ( 2019 ) . Abstract 2580: Investigation of plasma exosomal miRNA as a biomarker and its potential function in prostate cancer castration resistant development . Conference: Molecular and Cellular Biology / Genetics2580 - 2580 .
Wu L, Wang J, Cai Q, Cavazos TB, Emami NC, Long J, Shu X-O, Lu Y et al. ( 2019 ) . Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants . Cancer Research vol. 79 , ( 13 ) 3192 - 3204 .
Song D, Powles T, Shi L, Zhang L, Ingersoll MA, Lu Y ( 2019 ) . Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approaches . The Journal of Pathology vol. 249 , ( 2 ) 151 - 165 .
Law PJ, Timofeeva M, Fernandez-Rozadilla C, Broderick P, Studd J, Fernandez-Tajes J, Farrington S, Svinti V et al. ( 2019 ) . Association analyses identify 31 new risk loci for colorectal cancer susceptibility . Nature Communications vol. 10 , ( 1 )
Yeste-Velasco M, Guo T, Mao X, Stankiewicz E, Scandura G, Li H, Wang CS, Kudahetti S et al. ( 2019 ) . The potential of brentuximab vedotin, alone or in combination with current clinical therapies, in the treatment of testicular germ cell tumors . American Journal of Cancer Research vol. 9 , ( 5 ) 855 - 871 .
Matejcic M, Saunders EJ, Dadaev T, Brook MN, Wang K, Sheng X, Olama AAA, Schumacher FR et al. ( 2019 ) . Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry . Nature Communications vol. 10 , ( 1 )
Schumacher FR, Olama AAA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D et al. ( 2019 ) . Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci . Nature Genetics vol. 51 , ( 2 ) 363 - 363 .
Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Kote-Jarai Z, Eeles R, Freedman M et al. ( 2019 ) . Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions . Nature Communications vol. 10 , ( 1 )
Adams C, Richmond RC, Ferreira DLS, Spiller W, Tan VY, Zheng J, Wurtz P, Donovan JL et al. ( 2019 ) . Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study . Cancer Epidemiology Biomarkers & Prevention vol. 28 , ( 1 )
Xu L, Bastus NC, Lu Y-J ( 2019 ) . Chapter 15 Sequencing a Single Circulating Tumor Cell for Genomic Assessment . Oncogenomics , Elsevier
Xue X, Shi F, Dong L, Rong L, Li L, Zheng B, Liu X, Liu W et al. ( 2019 ) . Predisposition of Adrenocortical Carcinoma by Loss of Function of Mismatch Repair Genes and The Role of TP53 In Cancer Development . LABORATORY INVESTIGATION . vol. 99 ,
Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM et al. ( 2018 ) . Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia . Nature Communications vol. 9 , ( 1 )
Guo T, Wang Y, Mao X, Xu L, Marzec J, Burke E, Shaw G, Hines J et al. ( 2018 ) . Investigation of exosomal miRNA as biomarker for prostate cancer castration resistance development . BRITISH JOURNAL OF CANCER . Conference: NCRI Cancer Conferences vol. 119 , 32 - 32 .
Matejcic M, Saunders EJ, Dadaev T, Brook MN, Wang K, Sheng X, Olama AAA, Schumacher FR et al. ( 2018 ) . Germline variation at 8q24 and prostate cancer risk in men of European ancestry . Nature Communications vol. 9 , ( 1 )
Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Kote-Jarai Z, Eeles R, Freedman M et al. ( 2018 ) . Large-scale transcriptome-wide association study identifies new prostate cancer risk regions . Nature Communications vol. 9 , ( 1 )
Went M, Sud A, Försti A, Halvarsson B-M, Weinhold N, Kimber S, van Duin M, Thorleifsson G et al. ( 2018 ) . Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma . Nature Communications vol. 9 , ( 1 )
Adimonye A, Stankiewicz E, Touche SL, Kudahetti S, Tinwell B, Corbishley C, Lu Y-J, Watkin N et al. ( 2018 ) . The Prognostic Value of PIK3CA Copy Number Gain in Penile Cancer . Urology
Matejcic M, Saunders EJ, Dadaev T, Brook M, Olama AAA, Schumacher FR, Berndt SI, Benlloch S et al. ( 2018 ) . Abstract 227: Germline variation at 8q24 and prostate cancer risk in men of European ancestry . Cancer Research . vol. 78 , 227 - 227 .
Adimonye A, Stankiewicz E, La-Touche S, Kudahetti S, Trevisan G, Tinwell B, Corbishley C, Lu Y-J et al. ( 2018 ) . PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in varied disease states of penile cancer . PLoS ONE vol. 13 , ( 6 ) e0198905 - e0198905 .
Schumacher FR, Al Olama AA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D et al. ( 2018 ) . Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci . Nature Genetics vol. 50 , ( 7 ) 928 - 936 .
Dadaev T, Saunders EJ, Newcombe PJ, Anokian E, Leongamornlert DA, Brook MN, Cieza-Borrella C, Mijuskovic M et al. ( 2018 ) . Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants . Nature Communications vol. 9 , ( 1 )
Lin H-Y, Huang P-Y, Chen D-T, Tung H-Y, Sellers TA, Pow-Sang JM, Eeles R, Easton D et al. ( 2018 ) . AA9int: SNP interaction pattern search using non-hierarchical additive model set . Bioinformatics vol. 34 , ( 24 ) 4141 - 4150 .
Wedge DC, Gundem G, Mitchell T, Woodcock DJ, Martincorena I, Ghori M, Zamora J, Butler A et al. ( 2018 ) . Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets . Nature Genetics vol. 50 , ( 5 ) 682 - 692 .
Adimonye A, Stankiewicz E, Kudahetti S, Trevisan G, Tinwell B, Corbishley C, Lu Y-J, Watkin N et al. ( 2018 ) . Analysis of the PI3K-AKT-mTOR pathway in penile cancer: evaluation of a therapeutically targetable pathway . Oncotarget vol. 9 , ( 22 ) 16074 - 16086 .
Aguirre-Hernández C, Maya-Pineda H, Millán JS, Man YKS, Lu Y-J, Halldén G ( 2018 ) . Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus Ad∆∆ through Bcl-2-dependent attenuation of autophagy . Oncogenesis vol. 7 , ( 1 )
Xu L, Bastus NC, Lu YJ ( 2018 ) . Sequencing a single circulating tumor cell for genomic assessment . Oncogenomics: From Basic Research to Precision Medicine ,
Sud A, Thomsen H, Law PJ, Försti A, Filho MIDS, Holroyd A, Broderick P, Orlando G et al. ( 2017 ) . Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility . Nature Communications vol. 8 , ( 1 )
Aguirre-Hernandez C, Maya-Pineda H, Millan JS, Man YKS, Lu YJ, Hallden G ( 2017 ) . Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus Ad Delta Delta through Bcl-2-dependent attenuation of autophagy . HUMAN GENE THERAPY . Conference: ESGCT workshop Croatia vol. 28 , A26 - A26 .
Camacho N, Van Loo P, Edwards S, Kay JD, Matthews L, Haase K, Clark J, Dennis N et al. ( 2017 ) . Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data . PLoS Genet vol. 13 , ( 9 ) e1007001 - e1007001 .
Stankiewicz E, Xueying M, Mangham DC, Xu L, Yeste-Velasco M, Fisher G, North B, Chaplin T et al. ( 2017 ) . Identification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer . Scientific Reports Article 5124 ,
Xu L, Mao X, Guo T, Chan PY, Shaw G, Hines J, Stankiewicz E, Wang Y et al. ( 2017 ) . The novel association of circulating tumor cells and circulating megakaryocytes with prostate cancer prognosis . Clin Cancer Res
Adimonye A, Stankiewicz E, Nicholson S, Hall E, Kudahetti S, Rajab R, Corbishley C, Lu Y-J et al. ( 2017 ) . 709 PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in evolving disease states of penile cancer . European Urology Open Science vol. 16 , ( 3 ) e1228 - e1229 .
Lin H-Y, Chen D-T, Huang P-Y, Liu Y-H, Ochoa A, Zabaleta J, Mercante DE, Fang Z et al. ( 2016 ) . SNP interaction pattern identifier (SIPI): an intensive search for SNP–SNP interaction patterns . Bioinformatics vol. 33 , ( 6 ) 822 - 833 .
Berney DM, Lu Y, Shamash J, Idrees M ( 2016 ) . Postchemotherapy changes in testicular germ cell tumours: biology and morphology . Histopathology vol. 70 , ( 1 ) 26 - 39 .
Behjati S, Gundem G, Wedge DC, Roberts ND, Tarpey PS, Cooke SL, Van Loo P, Alexandrov LB et al. ( 2016 ) . Mutational signatures of ionizing radiation in second malignancies . Nature Communications vol. 7 , Article 12605 , 1 - 8 .
Mao X, Luo F, Boyd LK, Zhou B, Zhang Y, Stankiewicz E, Marzec J, Vasiljevic N et al. ( 2016 ) . NKAIN2 functions as a novel tumor suppressor in prostate cancer . Oncotarget
Imrali A, Mao X, Yeste-Velasco M, Shamash J, Lu Y ( 2016 ) . Rapamycin inhibits prostate cancer cell growth through cyclin D1 and enhances the cytotoxic efficacy of cisplatin . American Journal of Cancer Research vol. 6 , ( 8 ) 1772 - 1784 .
Jiang H, Mao X, Huang X, Zhao J, Wang L, Xu J, Zhang H, Lu Y et al. ( 2016 ) . Erratum to: TMPRSS2:ERG fusion gene occurs less frequently in Chinese patients with prostate cancer . Tumour Biol vol. 37 , ( 10 ) 14331 - 14331 .
Stankiewicz E, Mao X, Mangham DC, Xu L, Fisher G, North B, Moller H, Scardino P et al. ( 2016 ) . Identification of FBXL4 as a bone metastasis-associated gene in prostate cancer . Scientific Reports vol. 7 ,
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T et al. ( 2016 ) . Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study . PLoS Genet vol. 12 , ( 6 ) e1006166 - e1006166 .
Jiang H, Mao X, Huang X, Zhao J, Wang L, Xu J, Zhang H, Lu Y et al. ( 2016 ) . TMPRSS2:ERG fusion gene occurs less frequently in Chinese patients with prostate cancer . Tumor Biology vol. 37 , ( 9 ) 12397 - 12402 .
Wang Y, Shao N, Mao X, Zhu M, Fan W, Shen Z, Xiao R, Wang C et al. ( 2016 ) . MiR-4638-5p inhibits castration resistance of prostate cancer through repressing kidins220 expression and PI3K/AKT pathway activity . Oncotarget vol. 7 , ( 30 ) 47444 - 47464 .
Adimonve A, Stankiewicz E, Kudahetti S, Rajab R, Corbishley C, Lu Y-J, Watkin N, Berney D ( 2016 ) . 238 PIK3CA gene copy number and mRNA expression in invasive penile cancer . European Urology Open Science vol. 15 , ( 3 )
Marzec J, Mao X, Li M, Wang M, Feng N, Gou X, Wang G, Sun Z et al. ( 2016 ) . A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population . Oncotarget vol. 7 , ( 16 ) 21393 - 21403 .
Xu L, Mao X, Chan PY, Shamash J, Lu Y-J ( 2016 ) . Analysis of prostate cancer circulating tumour cells isolated with a novel size-based system . The Lancet . vol. 387 ,
Zhao S-C, Zhou B-W, Luo F, Mao X, Lu Y-J ( 2015 ) . The structure and function of NKAIN2-a candidate tumor suppressor . International Journal of Clinical and Experimental Medicine vol. 8 , ( 10 ) 17072 - 17079 .
Xu L, Mao X, Imrali A, Syed F, Mutsvangwa K, Berney D, Cathcart P, Hines J et al. ( 2015 ) . Optimization and Evaluation of a Novel Size Based Circulating Tumor Cell Isolation System . PLOS ONE vol. 10 , ( 9 )
Zhang Y, Mao X-Y, Liu X, Song R-R, Berney D, Lu Y-J, Ren G ( 2015 ) . High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer . International Journal of Clinical and Experimental Medicine vol. 8 , ( 9 ) 15127 - 15136 .
Olama AAA, Benlloch S, Antoniou AC, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL et al. ( 2015 ) . Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci . Cancer Epidemiology Biomarkers & Prevention vol. 24 , ( 7 ) 1121 - 1129 .
Yeste-Velasco M, Linder ME, Lu Y-J ( 2015 ) . Protein S-palmitoylation and cancer . Biochimica et Biophysica Acta vol. 1856 , ( 1 ) 107 - 120 .
Bao J-M, He M-Y, Liu Y-W, Lu Y-J, Hong Y-Q, Luo H-H, Ren Z-L, Zhao S-C et al. ( 2015 ) . AGE/RAGE/Akt pathway contributes to prostate cancer cell proliferation by promoting Rb phosphorylation and degradation . American Journal of Cancer Research vol. 5 , ( 5 ) 1741 - 1750 .
Coll-Bastus N, Mao X, Young BD, Sheer D, Lu Y-J ( 2015 ) . DNA replication-dependent induction of gene proximity by androgen . Hum Mol Genet vol. 24 , ( 4 ) 963 - 971 .
Lian W-Q, Luo F, Song X-L, Lu Y-J, Zhao S-C ( 2015 ) . Gonorrhea and Prostate Cancer Incidence: An Updated Meta-Analysis of 21 Epidemiologic Studies . Medical Science Monitor vol. 21 , 1895 - 1903 .
Mao X, Li J, Xu X, Boyd LK, He W, Stankiewicz E, Kudahetti SC, Cao G et al. ( 2014 ) . Involvement of different mechanisms for the association of CAG repeat length polymorphism in androgen receptor gene with prostate cancer . American Journal of Cancer Research vol. 4 , ( 6 ) 886 - 896 .
Ren G, Zhang Y, Mao X, Liu X, Mercer E, Marzec J, Ding D, Jiao Y et al. ( 2014 ) . Transcription-mediated chimeric RNAs in prostate cancer: time to revisit old hypothesis? . OMICS vol. 18 , ( 10 ) 615 - 624 .
Mercer EJ, Imrali A, Sharpe K, Hallden G, Lu Y-J ( 2014 ) . Abstract 713: Utilizing a potent and selective nonreplicating adenoviral mutant (Ad5-TV-CU), with gene expression controlled by androgen receptor-dependent activation domains in the TMPRSS2 gene, as a novel prodrug-converting enzyme therapy for prostate cancer . Conference: Experimental and Molecular Therapeutics713 - 713 .
( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol 2014; 232: 566–577 . The Journal of Pathology vol. 234 , ( 1 ) 134 - 134 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljević N, Chaplin T et al. ( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor gene . J Pathol vol. 232 , ( 5 ) 566 - 577 .
Allen MD, Luong P, Hudson C, Leyton J, Delage B, Ghazaly E, Cutts R, Yuan M et al. ( 2014 ) . Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging . Cancer Res vol. 74 , ( 3 ) 896 - 907 .
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell Death & Disease . vol. 5 , e1028 - e1028 .
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell Death Dis vol. 5 , ( 1 )
Zhang H, Fan Y, Ge N, Wang X, Sun W, Mao R, Bu W, Creighton CJ et al. ( 2014 ) . Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells . Journal of Pathology vol. 232 , ( 1 ) 75 - 86 .
Zhao C-B, Bao J-M, Lu Y-J, Zhao T, Zhou X-H, Zheng D-Y, Zhao S-C ( 2014 ) . Co-expression of RAGE and HMGB1 is associated with cancer progression and poor patient outcome of prostate cancer . Am J Cancer Res vol. 4 , ( 4 ) 369 - 377 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Marzec J, Vasiljevic N, Chaplin T, Foster JM et al. ( 2014 ) . Identification of <i>ZDHHC14</i> as a novel human tumour suppressor: gene . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S90 - S90 .
Bastus NC, Mao X, Young BD, Sheer D, Lu Y-J ( 2014 ) . Novel function of androgen receptor-the regulation of DNA replication and genomic movement . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .
Mao X, Marzec J, Li M, Zhang Z, Feng N, Gou X, Sun Z, Xu J et al. ( 2014 ) . Population differences in the genetic risk of prostate cancer and predisposition loci in the Chinese population . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .
Xu L, Irrami A, Shamash J, Lu Y-J ( 2014 ) . Size-based isolation of circulating tumour cells and its application in advanced prostate cancer . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .
Sharpe K, Stewart GD, Mackay A, Van Neste C, Rofe C, Berney D, Kayani I, Bex A et al. ( 2013 ) . The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer . Clin Cancer Res vol. 19 , ( 24 ) 6924 - 6934 .
Vasiljević N, Ahmad AS, Beesley C, Thorat MA, Fisher G, Berney DM, Møller H, Yu Y et al. ( 2013 ) . Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer . Prostate Cancer Prostatic Dis vol. 16 , ( 1 ) 35 - 40 .
Al Olama AA, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, Giles GG, Severi G et al. ( 2013 ) . A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease . HUMAN MOLECULAR GENETICS vol. 22 , ( 2 ) 408 - 415 .
Li J, Mercer E, Gou X, Lu Y-J ( 2013 ) . Ethnical disparities of prostate cancer predisposition: genetic polymorphisms in androgen-related genes . Am J Cancer Res vol. 3 , ( 2 ) 127 - 151 .
Ren G, Liu X, Mao X, Zhang Y, Stankiewicz E, Hylands L, Song R, Berney DM et al. ( 2012 ) . Identification of frequent BRAF copy number gain and alterations of RAF genes in chinese prostate cancer . Genes Chromosomes and Cancer vol. 51 , ( 11 ) 1014 - 1023 .
Boyd LK, Mao X, Lu Y-J ( 2012 ) . The complexity of prostate cancer: genomic alterations and heterogeneity . Nat Rev Urol vol. 9 , ( 11 ) 652 - 664 .
Boyd LK, Mao X, Xue L, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E, Yu Y et al. ( 2012 ) . High-resolution genome-wide copy-number analysis suggests a monoclonal origin of multifocal prostate cancer . Genes Chromosomes Cancer vol. 51 , ( 6 ) 579 - 589 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Chaplin T, Xue L, Xu M et al. ( 2012 ) . Abstract 4858: Identification of ZDHHC14 as a novel tumor suppressor gene commonly downregulated in human cancers . Cancer Research vol. 72 , ( 8_Supplement ) 4858 - 4858 .
Mao X, Coll Bastus N, Boyd L, Yu Y, Ren G, Beltran L, Oliver R, Young BD et al. ( 2012 ) . The different genetic alterations between Western and Chinese prostate cancers and the underlying mechanisms . J Clin Oncol vol. 30 , ( 5_suppl )
Lu YJ, Liu X, Mao X, Hylands L, Clark J, Cooper C, Ren G ( 2012 ) . Truncation of BRAF and Raf1 in prostate cancer in China . J Clin Oncol vol. 30 , ( 5_suppl )
Xue L, Mao X, Ren G, Stankiewicz E, Kudahetti SC, Lin D, Beltran L, Berney DM et al. ( 2012 ) . Chinese and Western prostate cancers show alternate pathogenetic pathways in association with ERG status . Am J Cancer Res vol. 2 , ( 6 ) 736 - 744 .
Ren G, Liu X, Mao X, Zhang Y, Stankiewicz E, Hylands L, Song R, Berney DM et al. ( 2012 ) . Identification of frequent BRAF copy number gain and alterations of RAF genes in chinese prostate cancer . Genes Chromosomes and Cancer
Mao X, Bastus NC, Boyd L, Yu Y, Ren G, Beltran L, Oliver R, Young BD et al. ( 2012 ) . The different genetic alterations between Western and Chinese prostate cancers and the underlying mechanisms . JOURNAL OF CLINICAL ONCOLOGY vol. 30 , ( 5 )
Lu Y-J, Liu X, Mao X, Hylands L, Clark J, Cooper C, Ren G ( 2012 ) . Truncation of BRAF and Raf1 in prostate cancer in China . JOURNAL OF CLINICAL ONCOLOGY vol. 30 , ( 5 )
Kote-Jarai Z, Al Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, Campa D, Riboli E et al. ( 2011 ) . Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study . NAT GENET vol. 43 , ( 8 ) 785 - U96 .
Lu YJ, Mao X, Yu Y, Boyd LK, Oliver RTD, Berney DM ( 2011 ) . Distinct genomic differences in prostate cancer between western countries and china . BRITISH JOURNAL OF SURGERY . vol. 98 , E3 - E3 .
Bastus NC, Lu Y-J, Boyd LK, Mao X, Stankiewicz E, Kudahetti SC, Oliver TD, Berney DM ( 2011 ) . Abstract 3048: Enhanced androgen signalling pathway increases the risk of prostate cancer through induction of TMPRSS2:ERG fusion . Cancer Research vol. 71 , ( 8_Supplement ) 3048 - 3048 .
Lu Y-J, Mao X, Xue L, Boyd LK, Kudahetti SC, Yu Y, Ren G, Lin D et al. ( 2011 ) . Abstract 3878: The different genetic alterations between Western and Chinese samples indicate alternate pathways of prostate cancer development . Cancer Research vol. 71 , ( 8_Supplement ) 3878 - 3878 .
Boyd LK, Xue L, Mao X, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E, Bisson I et al. ( 2011 ) . Abstract 4831: Monoclonal origin of multifocal cancer and the step-wise genetic events of prostate carcinogenesis . Cancer Research vol. 71 , ( 8_Supplement ) 4831 - 4831 .
Allen M, Syed N, Luong F, Howarth K, Gorman P, Tomlinson I, Roylance R, Lu Y-J et al. ( 2011 ) . Abstract 76: Epigenetic silencing of argininosuccinate synthetase renders human bladder cancer cells sensitive to pegylated arginine deiminase . Cancer Research vol. 71 , ( 8_Supplement ) 76 - 76 .
Stankiewicz E, Prowse DM, Ng M, Cuzick J, Mesher D, Hiscock F, Lu Y-J, Watkin N et al. ( 2011 ) . Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas . PLoS One vol. 6 , ( 3 )
Stankiewicz E, Mesher D, Ng M, Cuzick J, Prowse D, Hiscock F, Lu YJ, Lam W et al. ( 2011 ) . Alternative Pathways of Akt Pathway Activation in HPV Positive and Negative Penile Carcinomas . MODERN PATHOLOGY . vol. 24 , 225A - 226A .
Vasiljević N, Wu K, Brentnall AR, Kim DC, Thorat MA, Kudahetti SC, Mao X, Xue L et al. ( 2011 ) . Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing . Dis Markers vol. 30 , ( 4 ) 151 - 161 .
Mao X, Boyd LK, Yáñez-Muñoz RJ, Chaplin T, Xue L, Lin D, Shan L, Berney DM et al. ( 2011 ) . Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer . Am J Cancer Res vol. 1 , ( 5 ) 604 - 617 .
Bastus NC, Boyd LK, Mao X, Stankiewicz E, Kudahetti SC, Oliver RTD, Berney DM, Lu Y-J ( 2010 ) . Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells . Cancer Res vol. 70 , ( 23 ) 9544 - 9548 .
Lu Y-J, Noel EE, Yeste-Velasco M, Mao X, Perry J, Kudahetti SC, Li NF, Chaplin T et al. ( 2010 ) . CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other human cancers . Cancer Genetics vol. 203 , ( 1 )
Mao X, Yu Y, Boyd LK, Xue L, Ren G, Lin D, Chaplin T, Kudahetti S et al. ( 2010 ) . Distinct genomic differences in prostate cancer between Western countries and China . Cancer Genetics vol. 203 , ( 1 )
Boyd L, Mao X, Xue L, Chaplin T, Kudahetti S, Stankiewicz E, Berney D, Young B et al. ( 2010 ) . High-resolution genome-wide SNP analysis suggests a monoclonal origin of multiple prostate cancer foci . Cancer Genetics vol. 203 , ( 1 )
Mao X, Yu Y, Boyd LK, Ren G, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E et al. ( 2010 ) . Distinct genomic alterations in prostate cancers in Chinese and Western populations suggest alternative pathways of prostate carcinogenesis . Cancer Res vol. 70 , ( 13 ) 5207 - 5212 .
Noel EE, Yeste-Velasco M, Mao X, Perry J, Kudahetti SC, Li NF, Sharp S, Chaplin T et al. ( 2010 ) . The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers . Am J Pathol vol. 176 , ( 6 ) 2607 - 2615 .
Shan L, Ambroisine L, Clark J, Yáñez-Muñoz RJ, Fisher G, Kudahetti SC, Yang J, Kia S et al. ( 2010 ) . The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer . Prostate Cancer Prostatic Dis vol. 13 , ( 2 ) 117 - 125 .
Pantazi E, Trigiante G, Warnes G, Gemenetzidis E, Teh MT, Ikram M, Shan L, Lu YJ et al. ( 2010 ) . Overexpression of GLI2 in human keratinocytes results in resistance to ultraviolet B-induced apoptosis and increased chromosomal instability . BRITISH JOURNAL OF DERMATOLOGY . vol. 162 , 948 - 948 .
Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL et al. ( 2009 ) . Identification of seven new prostate cancer susceptibility loci through a genome-wide association study . NAT GENET vol. 41 , ( 10 ) 1116 - U97 .
Shan L, Ambroisine L, Clark J, Yanez-Munoz R, Fisher G, Kudahetti S, Foster C, Reuter V et al. ( 2009 ) . POD-04.07: A New Recurrent Chromosomal Translocation, T(4;6)(q22;q15), in Prostate Cancer . Urology vol. 74 , ( 4 )
Perry J, Powles T, Shamash J, Veerupillai A, McGrowder E, Noel E, Lu Y-J, Oliver T et al. ( 2009 ) . The relative activity of cisplatin, oxaliplatin and satraplatin in testicular germ cell tumour sensitive and resistant cell lines . Cancer Chemother Pharmacol vol. 64 , ( 5 ) 925 - 933 .
Cai X, Xiao T, James SY, Da J, Lin D, Liu Y, Zheng Y, Zou S et al. ( 2009 ) . Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2 . Lung Cancer vol. 65 , ( 3 ) 299 - 305 .
Boyd LK, Mao X, Lu YJ ( 2009 ) . Use of SNPs in cancer predisposition analysis, diagnosis and prognosis: Tools and prospects . Expert Opinion on Medical Diagnostics vol. 3 , ( 3 ) 313 - 326 .
Mao X, Young BD, Chaplin T, Shipley J, Lu Y-J ( 2008 ) . Subtle genomic alterations and genomic instability revealed in diploid cancer cell lines . Cancer Lett vol. 267 , ( 1 ) 49 - 54 .
Noel EE, Perry J, Chaplin T, Mao X, Cazier J-B, Joel SP, Oliver RTD, Young BD et al. ( 2008 ) . Identification of genomic changes associated with cisplatin resistance in testicular germ cell tumor cell lines . Genes Chromosomes Cancer vol. 47 , ( 7 ) 604 - 613 .
Mao X, Shaw G, James SY, Purkis P, Kudahetti SC, Tsigani T, Kia S, Young BD et al. ( 2008 ) . Detection of TMPRSS2:ERG fusion gene in circulating prostate cancer cells . Asian J Androl vol. 10 , ( 3 ) 467 - 473 .
Lane T, Hines J, Strefford J, Lu YJ, Yanez-Munoz R, Oliver T ( 2008 ) . The t(4;6) chromosomal translocation is a recurrent event in prostate cancer . EUR UROL SUPPL vol. 7 , ( 3 ) 272 - 272 .
Noel EE, Ragavan N, Walsh MJ, James SY, Matanhelia SS, Nicholson CM, Lu Y-J, Martin FL ( 2008 ) . Differential gene expression in the peripheral zone compared to the transition zone of the human prostate gland . Prostate Cancer Prostatic Dis vol. 11 , ( 2 ) 173 - 180 .
McIntyre A, Summersgill B, Lu YJ, Missiaglia E, Kitazawa S, Oosterhuis JW, Looijenga LH, Shipley J ( 2007 ) . Genomic copy number and expression patterns in testicular germ cell tumours . BRIT J CANCER vol. 97 , ( 12 ) 1707 - 1712 .
Li NF, Broad S, Lu YJ, Yang JS, Watson R, Hagemann T, Wilbanks G, Jacobs I et al. ( 2007 ) . Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression . Cell Prolif vol. 40 , ( 5 ) 780 - 794 .
Mao X, James SY, Yáñez-Muñoz RJ, Chaplin T, Molloy G, Oliver RTD, Young BD, Lu Y-J ( 2007 ) . Rapid high-resolution karyotyping with precise identification of chromosome breakpoints . Genes Chromosomes Cancer vol. 46 , ( 7 ) 675 - 683 .
Zhou YP, Ye HT, Martin-Subero JI, Gesk S, Hamoudi R, Lu YJ, Wang R, Shipley J et al. ( 2007 ) . The pattern of genomic gains in salivary gland MALT lymphomas . HAEMATOL-HEMATOL J vol. 92 , ( 7 ) 921 - 927 .
Mao X, Young BD, Lu Y-J ( 2007 ) . The application of single nucleotide polymorphism microarrays in cancer research . Curr Genomics vol. 8 , ( 4 ) 219 - 228 .
Lane TM, Strefford JC, Yáñez-Muñoz RJ, Purkis P, Forsythe E, Nia T, Hines J, Lu Y-J et al. ( 2007 ) . Identification of a recurrent t(4;6) chromosomal translocation in prostate cancer . J Urol vol. 177 , ( 5 ) 1907 - 1912 .
Williamson D, Selfe J, Gordon T, Lu YJ, Pritchard-Jones K, Murai K, Jones P, Workman P et al. ( 2007 ) . Role for amplification and expression of Glypican-5 in rhabdomyosarcoma . CANCER RES vol. 67 , ( 1 ) 57 - 65 .
Williamson D, Lu YJ, Fang C, Pritchard-Jones K, Shipley J ( 2006 ) . Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma . GENE CHROMOSOME CANC vol. 45 , ( 9 ) 839 - 845 .
Ma J, Gao M, Lu Y, Feng X, Zhang J, Lin D, Xiao T, Hu Z et al. ( 2006 ) . Gain of 1q25–32, 12q23–24.3, and 17q12–22 facilitates tumorigenesis and progression of human squamous cell lung cancer . The Journal of Pathology vol. 210 , ( 2 ) 205 - 213 .
Wilson C, Yang J, Strefford JC, Summersgill B, Young BD, Shipley J, Oliver T, Lu Y-J ( 2006 ) . Overexpression of Genes on 16q Associated With Cisplatin Resistance of Testicular Germ Cell Tumor Cell Lines . Investigative Urology vol. 175 , ( 5 ) 1708 - 1709 .
Zhou YP, Ye HT, Martin-Subero JI, Hamoudi R, Lu YJ, Wang R, Siebert R, Shipley J et al. ( 2006 ) . Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21) . BRIT J HAEMATOL vol. 133 , ( 1 ) 35 - 42 .
Kote-Jarai Z, Salmon A, Mengitsu T, Copeland M, Ardern-Jones A, Locke I, Shanley S, Summersgill B et al. ( 2006 ) . Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers . BRIT J CANCER vol. 94 , ( 2 ) 308 - 310 .
Noel EE, Perry J, Li NF, Chaplin T, Young BD, Oliver T, Joel SP, Lu Y-J ( 2006 ) . Identification of genes leading to cisplatin-resistance in testicular germ cell tumours . CANCER RESEARCH . vol. 66 ,
Lu Y-J, Yang J, Noel E, Mao X, Skoulakis S, Chaplin T, Raghavan M, Purkis T et al. ( 2006 ) . Large scale genomic homozygosity and non-seminomatous testicular germ tumour development . CANCER RESEARCH . vol. 66 ,
Strefford JC, Lane TM, Hill A, LeRoux L, Foot NJ, Shipley J, Oliver RTD, Lu Y-J et al. ( 2006 ) . Molecular characterisation of the t(1;15)(p22;q22) translocation in the prostate cancer cell line LNCaP . Cytogenet Genome Res vol. 112 , ( 1-2 ) 45 - 52 .
Lu Y-J, Yang J, Noel E, Skoulakis S, Chaplin T, Raghavan M, Purkis T, McIntyre A et al. ( 2005 ) . Association between large-scale genomic homozygosity without chromosomal loss and nonseminomatous germ cell tumor development . Cancer Res vol. 65 , ( 20 ) 9137 - 9141 .
Wilson C, Yang J, Strefford JC, Summersgill B, Young BD, Shipley J, Oliver T, Lu Y-J ( 2005 ) . Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines . Genes Chromosomes Cancer vol. 43 , ( 2 ) 211 - 216 .
Strefford JC, Stasevich I, Lane TM, Lu Y-J, Oliver T, Young BD ( 2005 ) . A combination of molecular cytogenetic analyses reveals complex genetic alterations in conventional renal cell carcinoma . Cancer Genet Cytogenet vol. 159 , ( 1 ) 1 - 9 .
Williamson D, Lu YJ, Gordon T, Sciot R, Kelsey A, Fisher C, Poremba C, Anderson J et al. ( 2005 ) . Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype . J CLIN ONCOL vol. 23 , ( 4 ) 880 - 888 .
Williamson D, Lu YJ, McIntyre A, Summersgill B, Wang RB, Selfe J, Cooper C, Clark J et al. ( 2004 ) . Comparative genomic hybridisation and comparative expressed sequence hybridisation as complements to microarray analyses of tumours . MUTAGENESIS vol. 19 , ( 6 ) 509 - 509 .
Lu YJ, Williamson D, Wang R, Summersgill B, Rodriguez S, Rogers S, Pritchard-Jones K, Campbell C et al. ( 2003 ) . Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior . GENE CHROMOSOME CANC vol. 38 , ( 3 ) 207 - 214 .
Wang R, Titley JC, Lu YJ, Summersgill BM, Bridge JA, Fisher C, Shipley J ( 2003 ) . Loss of 13q14-q21 and gain of 5p14-pter in the progression of leiomyosarcoma . MODERN PATHOL vol. 16 , ( 8 ) 778 - 785 .
Osin P, Lu YJ, Stone J, Crook T, Houlston RS, Gasco M, Gusterson BA, Shipley J ( 2003 ) . Distinct genetic and epigenetic changes in medullary breast cancer . INT J SURG PATHOL vol. 11 , ( 3 ) 153 - 158 .
Rodriguez S, Jafer O, Goker H, Summersgill BM, Zafarana G, Gillis AJM, van Gurp RJHLM, Oosterhuis JW et al. ( 2003 ) . Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2-p12.1 . ONCOGENE vol. 22 , ( 12 ) 1880 - 1891 .
Barker KT, Bevan S, Wang R, Lu YJ, Flanagan AM, Bridge JA, Fisher C, Finlayson CJ et al. ( 2002 ) . Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas . BRIT J CANCER vol. 87 , ( 4 ) 446 - 448 .
Lu YJ, Hing S, Williams R, Pinkerton R, Shipley J, Pritchard-Jones K, UK Childrens Canc Study Grp ( 2002 ) . Chromosome 1q expression profiling and relapse in Wilms' tumour . LANCET vol. 360 , ( 9330 ) 385 - 386 .
Lu YJ, Williamson D, Clark J, Wang R, Tiffin N, Skelton L, Gordon T, Williams R et al. ( 2001 ) . Comparative expressed sequence hybridization to chromosomes for tumor classification and identification of genomic regions of differential gene expression . P NATL ACAD SCI USA vol. 98 , ( 16 ) 9197 - 9202 .
Summersgill B, Osin P, Lu YJ, Huddart R, Shipley J ( 2001 ) . Chromosomal imbalances associated with carcinoma in situ and associated testicular germ cell tumours of adolescents and adults . Br J Cancer vol. 85 , ( 2 ) 213 - 220 .
Wang R, Lu YJ, Fisher C, Bridge JA, Shipley J ( 2001 ) . Characterization of chromosome aberrations associated with soft-tissue leiomyosarcomas by twenty-four-color karyotyping and comparative genomic hybridization analysis . GENE CHROMOSOME CANC vol. 31 , ( 1 ) 54 - 64 .
Lu YJ, Condie A, Bennett JD, Fry MJ, Yuille MR, Shipley J ( 2001 ) . Disruption of the ATM gene in breast cancer . CANCER GENET CYTOGEN vol. 126 , ( 2 ) 97 - 101 .
Hing S, Lu YJ, Summersgill B, King-Underwood L, Nicholson J, Grundy P, Grundy R, Gessler M et al. ( 2001 ) . Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors . Am J Pathol vol. 158 , ( 2 ) 393 - 398 .
Cheng S, Gao Y, Dong X, Lu Y, An Q, Tong T, Wang Y ( 2001 ) . Molecular and cytogenetic alterations in early stage of carcinogenesis of human lung . Cancer Lett vol. 162 Suppl , S5 - S10 .
Jones C, Foschini MP, Chaggar R, Lu Y-J, Wells D, Shipley JM, Eusebi V, Lakhani SR ( 2000 ) . Comparative Genomic Hybridization Analysis of Myoepithelial Carcinoma of the Breast . Laboratory Investigation vol. 80 , ( 6 ) 831 - 836 .
Jones C, Foschini M, Chaggar R, Lu Y-J, Wells D, Shipley J, Eusebi V, Lakhani S ( 2000 ) . Comparative genomic hybridisation analysis of myoepithelial carcinoma of the breast . Breast Cancer Research vol. 2 , ( Suppl 1 )
Lu Y-J, Morris JS, Edwards PAW, Shipley J ( 2000 ) . Evaluation of 24-color Multifluor-Fluorescence In-situ Hybridization (M-FISH) Karyotyping by Comparison with Reverse Chromosome Painting of the Human Breast Cancer Cell Line T-47D . Chromosome Research vol. 8 , ( 2 ) 127 - 132 .
Birdsall S, Osin P, Lu Y, Fisher C, Shipley J ( 1999 ) . Synovial sarcoma specific translocation associated with both epithelial and spindle cell components . International Journal of Cancer vol. 82 , ( 4 ) 605 - 608 .
Lu Y, Birdsall S, Summersgill B, Smedley D, Osin P, Fisher C, Shipley J ( 1999 ) . Dual colour fluorescence in situ hybridization to paraffin‐embedded samples to deduce the presence of the der(X)t(X;18)(p11.2;q11.2) and involvement of either the SSX1 or SSX2 gene: a diagnostic and prognostic aid for synovial sarcoma . The Journal of Pathology vol. 187 , ( 4 ) 490 - 496 .
Smedley D, Hamoudi R, Lu Y-J, Cooper C, Shipley J ( 1999 ) . Cloning and Mapping of Members of the MYM Family . Genomics vol. 60 , ( 2 ) 244 - 247 .
Lu Y-J, Dong X-Y, Shipley J, Zhang R-G, Cheng S-J ( 1999 ) . Chromosome 3 imbalances are the most frequent aberration found in non-small cell lung carcinoma . Lung Cancer vol. 23 , ( 1 ) 61 - 66 .
Lu Y, Birdsall S, Osin P, Gusterson B, Shipley J ( 1998 ) . Phyllodes tumors of the breast analyzed by comparative genomic hybridization and association of increased 1q copy number with stromal overgrowth and recurrence . Genes Chromosomes and Cancer vol. 20 , ( 3 ) 275 - 281 .
Rozycka M, Lu Y-J, Brown RA, Lau MR, Shipley JM, Fry MJ ( 1998 ) . cDNA Cloning of a Third Human C2-Domain-Containing Class II Phosphoinositide 3-Kinase, PI3K-C2γ, and Chromosomal Assignment of This Gene (PIK3C2G) to 12p12 . Genomics vol. 54 , ( 3 ) 569 - 574 .
Lu Y ( 1998 ) . Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia . Cancer Research vol. 58 , ( 20 ) 4721 - 4727 .
Lu Y-J, Guo S-P, Tong T, Xu L-H, Dong X-Y, Hana N-J, Cheng S-J ( 1998 ) . Establishment and characterization of a SV40T-transformed human bronchial epithelial cell line . Lung Cancer vol. 19 , ( 1 ) 15 - 24 .
Osin P, Shipley J, Lu YJ, Crook T, Gusterson BA ( 1998 ) . Experimental Pathology and Breast Cancer Genetics: New Technologies . vol. 152 , 35 - 48 .
Clark J, Lu Y-J, Sidhar SK, Parker C, Gill S, Smedley D, Hamoudi R, Linehan WM et al. ( 1997 ) . Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma . Oncogene vol. 15 , ( 18 ) 2233 - 2239 .
Lu Y-J, Lakhani SR, Summersgill B, Sloane JP, Gusterson BA, Shipley JM ( 1997 ) . Gains and losses of genomic material in fibroadenenoma, carcinoma in situ and atypical hyperplasia of the breast analyzed by comparative genomic hybridization . Cancer Genetics . vol. 98 ,
Lu Y-J, Cheng S-J, Ning J, Dong X-Y ( 1997 ) . An accelerated in situ hybridization procedure using microwave irradiation . Chromosome Research vol. 5 , ( 2 ) 147 - 149 .
Dong X, Lu Y, Tong T, Wang Y, Guo S, Bai J, Han N, Cheng S ( 1997 ) . Molecular cytogenetic alterations in the early stage at human bronchial epithelial cell carcinogenesis . Journal of cellular biochemistry. Abstracts supplement vol. 67 , ( S28‒29 ) 74 - 80 .
Smith PD, Barker KT, Wang J, Lu Y-J, Shipley J, Crompton MR ( 1996 ) . ICAAR, a Novel Member of a New Family of Transmembrane, Tyrosine Phosphatase-like Proteins . Biochemical and Biophysical Research Communications vol. 229 , ( 2 ) 402 - 411 .
Lu YJ, Dong XY, Guo SP, Ke Y, Cheng SJ ( 1996 ) . Integration of SV40 at 12q23 in SV40-immortalized human bronchial epithelial cells . Carcinogenesis vol. 17 , ( 9 ) 2089 - 2091 .
Lu Y-J, Dong X-Y, Guo S-P, Zhang R-G, Ke Y, Zhang L-Z, Xu L-H, Cheng S-J ( 1996 ) . 2q-, a non-random chromosomal abnormality in human non-small-cell lung cancer . Carcinogenesis vol. 17 , ( 8 ) 1589 - 1593 .
Lu Y, Cheng S, Guo S ( 1996 ) . [C-myc activation by translocation in human primary non-small cell lung cancer] . National Medical Journal of China vol. 76 , ( 4 ) 275 - 277 .
Lu Y, Cheng S, Guo S ( 1995 ) . [Detection of c-myc translocation in human lung cancer cells by fluorescence in situ hybridization (FISH)] . National Medical Journal of China vol. 75 , ( 4 ) 214 - 255 .
Lu Y-J, Xiao S, Yan Y-S, Fu S-B, Liu Q-Z, Li P ( 1993 ) . Direct chromosome analysis of 50 primary breast carcinomas . Cancer Genetics vol. 69 , ( 2 ) 91 - 99 .