Publications: Prof Hemant Kocher

Gupta P, Bermejo‐Rodriguez C, Kocher H, Pérez‐Mancera PA, Velliou EG ( 2024 ) . Chemotherapy Assessment in Advanced Multicellular 3D Models of Pancreatic Cancer: Unravelling the Importance of Spatiotemporal Mimicry of the Tumor Microenvironment . Advanced Biology

Nowinski S, Balarajah V, Baker A-M, Katainen R, Hughes C, Guo Q, Zapata L, Lakatos E et al. ( 2024 ) . Abstract B011: Lower incidence of small intestinal adenocarcinomas may be due to constrained copy number karyotype and increased immune surveillance . Cancer Research vol. 84 , ( 3_Supplement_2 ) b011 - b011 .

Aguirre GA, Goulart MR, Bank BPT, Dalli J, Kocher HM ( 2024 ) . Corrigendum: Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion . Frontiers in Immunology vol. 15 ,

Ang A, Michaelides A, Bank BPT, Kocher H ( 2024 ) . Prognostication for Patterns of Recurrence After Surgical Resection for Pancreatic Adenocarcinoma . European Journal of Surgical Oncology vol. 50 , ( 1 )

Ang A, Michaelides A, Bank BPT, Kocher H ( 2023 ) . HPB P27 Prognostication for Patterns of Recurrence After Surgical Resection for Pancreatic Adenocarcinoma . British Journal of Surgery vol. 110 , ( Supplement_8 )

Aguirre GA, Goulart MR, Bank BPT, Dalli J, Kocher HM ( 2023 ) . Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion . Frontiers in Immunology vol. 14 ,

Fusai GK, Raptis DA, Abu Hilal M, Bassi C, Besselink M, Conlon K, Davidson B, Del Chiaro M et al. ( 2023 ) . Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries . British Journal of Surgery vol. 111 , ( 1 )

Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, KohIhammer L et al. ( 2023 ) . CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells . Science Advances vol. 9 , ( 42 )

Ang A, Michaelides A, Bank BPT, Kocher H ( 2023 ) . 795 Predictors and Timing of Recurrence After Surgical Resection of Pancreatic Adenocarcinoma . British Journal of Surgery vol. 110 , ( Supplement_7 )

Borakati A, Hughes F, Kocher H, Malik H ( 2023 ) . SP9.5 Outcomes after Emergency Cholecystectomy: A Multicentre Retrospective Cohort Study . British Journal of Surgery vol. 110 , ( Supplement_6 )

Okail MH, Kocher H, Cameron A ( 2023 ) . Investigating the Role of Protein Kinase N2 (PKN2) in Pancreatic Ductal Adenocarcinoma . Pancreatology vol. 23 , ( 4 )

Kocher H ( 2023 ) . Paget Lecture: an introduction . Pancreatology vol. 23 , ( 4 )

Ang A, Michaelides A, Bank BPT, Kocher H ( 2023 ) . Patterns and Predictors of Recurrence After Surgical Resection of Pancreatic Adenocarcinoma . Pancreatology vol. 23 , ( 4 )

Roy M, Kocher HM ( 2023 ) . Pancreatitis sepsis: Evolution and principles in the management of necrotizing pancreatitis . Surgery vol. 174 , ( 2 ) 406 - 409 .

Passman AM, Haughey MJ, Carlotti E, Williams MJ, Cereser B, Lin M-L, Devkumar S, Gabriel JP et al. ( 2023 ) . Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver . Journal of Hepatology vol. 79 , ( 2 ) 417 - 432 .

Goodburn L, Hughes T, Perry R, Walters M, Acharya R, Binnersly T, Brown SJ, Everitt R et al. ( 2023 ) . The impact of the COVID-19 pandemic upon pancreatic cancer treatment (CONTACT Study): a UK national observational cohort study . British Journal of Cancer vol. 128 , ( 10 ) 1922 - 1932 .

Bort ET, Joseph MD, Wang Q, Carter EP, Roth NJ, Gibson J, Samadi A, Kocher HM et al. ( 2023 ) . Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion . eLife vol. 12 ,

Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C et al. ( 2023 ) . Correction: Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1 . Oncogene vol. 42 , ( 7 ) 545 - 545 .

Gupta P, Kocher H, Singh B, Wilkinson JM, Mancera PAP, Velliou EG ( 2023 ) . Chemotherapeutic Screening on a Scaffold based Dynamic <i>In Vitro</i> Multicellular Models Pancreatic Cancer . TISSUE ENGINEERING PART A . vol. 29 ,

Gupta P, Kataki AD, Cheema U, Nisbet A, Wang Y, Kocher H, Mancer PAP, Velliou EG ( 2023 ) . Modelling the Extracellular Matrix Complexity in a Multi-Compartmental Biomaterial based Multicellular 3D Pancreatic Cancer Model . TISSUE ENGINEERING PART A . vol. 29 ,

Gupta P, Kataki AD, Perez-Mancer PA, Kocher H, Nisbet A, Schettino G, Velliou E ( 2023 ) . ON THE OPTIMISATION AND TAILORING OF THE ECM COMPLEXITY TO THE CANCER AND STROMAL CELLULAR COMPARTMENTS OF A BIOMATERIAL BASED NOVEL 3D MODEL OF PANCREATIC CANCER TISSUE . TISSUE ENGINEERING PART A . vol. 29 , 983 - 984 .

Zardab M, Balarajah V, Banerjee A, Stasinos K, Saad A, Imrali A, Hughes C, Roberts R et al. ( 2022 ) . Differentiating Ductal Adenocarcinoma of the Pancreas from Benign Conditions Using Routine Health Records: A Prospective Case-Control Study . Cancers vol. 15 , ( 1 )

Usman OH, Zhang L, Xie G, Kocher HM, Hwang C-I, Wang YJ, Mallory X, Irianto J . Genomic heterogeneity in pancreatic cancer organoids and its stability with culture . npj Genomic Medicine . vol. 7 ,

Usman OH, Zhang L, Xie G, Kocher HM, Hwang CI, Wang YJ, Mallory X, Irianto J ( 2022 ) . Genomic heterogeneity in pancreatic cancer organoids and its stability with culture . npj Genomic Medicine vol. 7 , ( 1 )

Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C et al. ( 2022 ) . Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1 . Oncogene vol. 42 , ( 7 ) 491 - 500 .

Neuzillet C, Nicolle R, Raffenne J, Tijeras‐Raballand A, Brunel A, Astorgues‐Xerri L, Vacher S, Arbateraz F et al. ( 2022 ) . Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma . The Journal of Pathology vol. 258 , ( 4 ) 408 - 425 .

Lawrence PV, Desai K, Wadsworth C, Mangal N, Kocher HM, Habib N, Sadanandam A, Sodergren MH ( 2022 ) . A Case Report on Longitudinal Collection of Tumour Biopsies for Gene Expression-Based Tumour Microenvironment Analysis from Pancreatic Cancer Patients Treated with Endoscopic Ultrasound Guided Radiofrequency Ablation . Current Oncology vol. 29 , ( 10 ) 6754 - 6763 .

Auwercx J, Kischel P, Lefebvre T, Jonckheere N, Vanlaeys A, Guénin S, Radoslavova S, Van Seuningen I et al. ( 2022 ) . TRPM7 Modulates Human Pancreatic Stellate Cell Activation . Cells vol. 11 , ( 14 )

Sivapalan L, Kocher HM, Ross-Adams H, Chelala C ( 2022 ) . The molecular landscape of pancreatic ductal adenocarcinoma . Pancreatology vol. 22 , ( 7 ) 925 - 936 .

Fotopoulou C, Khan T, Bracinik J, Glasbey J, Abu-Rustum N, Chiva L, Fagotti A, Fujiwara K et al. ( 2022 ) . Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study . American Journal of Obstetrics and Gynecology vol. 227 , ( 5 ) 735.e1 - 735.e25 .

Menezes S, Okail MH, Jalil SMA, Kocher HM, Cameron AJM ( 2022 ) . Cancer‐associated fibroblasts in pancreatic cancer: new subtypes, new markers, new targets . The Journal of Pathology vol. 257 , ( 4 ) 526 - 544 .

Lamarca A, Roberts K, Graham J, Kocher H, Chang D, Ghaneh P, Jamieson N, Propper D et al. ( 2022 ) . P-85 Pre-surgical staging and surveillance after curative treatment for pancreatic ductal adenocarcinoma (PDAC): Survey of practice in the United Kingdom (UK) . Annals of Oncology vol. 33 , s278 - s279 .

Baleeiro RB, Bouwens CJ, Liu P, Di Gioia C, Dunmall LSC, Nagano A, Gangeswaran R, Chelala C et al. ( 2022 ) . MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy . OncoImmunology vol. 11 , ( 1 )

Ang A, Michaelides A, Hallworth S, Kocher HM ( 2022 ) . Intraoperative acute compartment syndrome of the upper limb secondary to extravasation . BMJ Case Reports vol. 15 , ( 5 )

Sivapalan L, Thorn GJ, Gadaleta E, Kocher HM, Ross-Adams H, Chelala C ( 2022 ) . Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer . BMC Cancer vol. 22 , ( 1 )

Delvecchio FR, Goulart MR, Fincham REA, Bombadieri M, Kocher HM ( 2022 ) . B cells in pancreatic cancer stroma . World Journal of Gastroenterology vol. 28 , ( 11 ) 1088 - 1101 .

Kartal E, Schmidt TSB, Molina-Montes E, Rodríguez-Perales S, Wirbel J, Maistrenko OM, Akanni WA, Alhamwe BA et al. ( 2022 ) . A faecal microbiota signature with high specificity for pancreatic cancer . Gut vol. 71 , ( 7 ) 1359 - 1372 .

Michaelides A, Ang A, ChinAleong J, Kocher HM ( 2022 ) . Large desmoid tumour of the small bowel mesentery . BMJ Case Reports vol. 15 , ( 3 )

Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A et al. ( 2022 ) . Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion . Cell Reports vol. 38 , ( 4 )

Zardab M, Stasinos K, Grose RP, Kocher HM ( 2022 ) . The Obscure Potential of AHNAK2 . Cancers vol. 14 , ( 3 )

Collaborative CS ( 2022 ) . Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection . BJS Open vol. 5 , ( 6 )

Roy M, Banerjee A, Simpfendorfer C, Kocher H, Wexner S, Ogunbayo OA ( 2022 ) . Prognostic Role of Circulating Tumor Cells in Resectable Colorectal Liver Metastases . Hepato Pancreato Biliary vol. 24 ,

Gupta P, Perez-Mancera P, Kocher H, Nisbet A, Schettino G, Velliou E ( 2022 ) . TOWARDS A BIOINSPIRED CONTROL OF THE PANCREATIC TUMOUR MICROENVIRONMENT: INCORPORATION OF INTERSTITIAL FLOW ON A MULTICELLULAR SCAFFOLD BASED PANCREATIC CANCER MODEL . TISSUE ENGINEERING PART A . vol. 28 , S17 - S17 .

Goulart MR, Stasinos K, Fincham REA, Delvecchio FR, Kocher HM ( 2021 ) . T cells in pancreatic cancer stroma . World Journal of Gastroenterology vol. 27 , ( 46 ) 7956 - 7968 .

Hitchman L, Machin M ( 2021 ) . Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data . The Journal of Cardiovascular Surgery vol. 62 , ( 6 ) 558 - 570 .

Dayem Ullah AZM, Stasinos K, Chelala C, Kocher HM ( 2021 ) . Temporality of clinical factors associated with pancreatic cancer: a case-control study using linked electronic health records . BMC Cancer vol. 21 , ( 1 )

McLean KA, Kamarajah SK, Chaudhry D, Gujjuri RR, Raubenheimer K, Trout I, Ameer EA, Creagh-Brown B et al. ( 2021 ) . Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic . British Journal of Surgery vol. 108 , ( 12 ) 1448 - 1464 .

Glasbey J, Ademuyiwa A, Adisa A, AlAmeer E, Arnaud AP, Ayasra F, Azevedo J, Minaya-Bravo A et al. ( 2021 ) . Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study . The Lancet Oncology vol. 22 , ( 11 ) 1507 - 1517 .

Nepogodiev D, Simoes JF, Li E, Picciochi M, Glasbey JC, Baiocchi G, Blanco‐Colino R, Chaudhry D et al. ( 2021 ) . SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study . Anaesthesia vol. 77 , ( 1 ) 28 - 39 .

Collaborative C, Collaborative G ( 2021 ) . Effects of pre‐operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study . Anaesthesia vol. 76 , ( 11 ) 1454 - 1464 .

Koenis DS, Beegun I, Jouvene CC, Aguirre GA, Souza PR, Gonzalez-Nunez M, Ly L, Pistorius K et al. ( 2021 ) . Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19 . Circulation ResearchE54 - E71 .

Delvecchio FR, Fincham REA, Spear S, Clear A, Roy-Luzarraga M, Balkwill FR, Gribben JG, Bombardieri M et al. ( 2021 ) . Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice . Cellular and Molecular Gastroenterology and Hepatology vol. 12 , ( 5 ) 1543 - 1565 .

Dajti I, Valenzuela JI, Boccalatte LA, Gemelli NA, Smith DE, Dudi-Venkata NN, Kroon HM, Sammour T et al. ( 2021 ) . Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score . British Journal of Surgery vol. 108 , ( 11 ) 1274 - 1292 .

Goulart MR, Watt J, Siddiqui I, Lawlor RT, Imrali A, Hughes C, Saad A, ChinAleong J et al. ( 2021 ) . Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma . npj Precision Oncology vol. 5 , ( 1 )

Fincham REA, Delvecchio FR, Goulart MR, Yeong JPS, Kocher HM ( 2021 ) . Natural killer cells in pancreatic cancer stroma . World Journal of Gastroenterology vol. 27 , ( 24 ) 3483 - 3501 .

Dayem Ullah AZM, Sivapalan L, Kocher HM, Chelala C ( 2021 ) . COVID-19 in patients with hepatobiliary and pancreatic diseases: a single-centre cross-sectional study in East London . BMJ Open vol. 11 , ( 4 )

Carter EP, Coetzee AS, Tomas Bort E, Wang Q, Kocher HM, Grose RP ( 2021 ) . Dissecting FGF Signalling to Target Cellular Crosstalk in Pancreatic Cancer . Cells vol. 10 , ( 4 )

Mortoglou M, Tabin ZK, Arisan ED, Kocher HM, Uysal-Onganer P ( 2021 ) . Non-coding RNAs in pancreatic ductal adenocarcinoma: New approaches for better diagnosis and therapy . Translational Oncology vol. 14 , ( 7 )

Akowuah E, Benson RA, Caruana EJ, Chetty G, Edwards J, Forlani S, Gradinariu G, Murphy GJ et al. ( 2021 ) . Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study . Journal of Thoracic and Cardiovascular Surgery vol. 162 , ( 2 ) e355 - e372 .

Collaborative GCC ( 2021 ) . SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study . British Journal of Surgery vol. 108 , ( 9 )

Pinato DJ, Cortellini A, Sukumaran A, Cole T, Pai M, Habib N, Spalding D, Sodergren MH et al. ( 2021 ) . PRIME-HCC: phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma . BMC Cancer vol. 21 , ( 1 )

McKay SC, Pathak S, Wilkin RJW, Kamarajah SK, Wigmore SJ, Rees J, Dunne DFJ, Garcea G et al. ( 2021 ) . Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience . Hepato Pancreato Biliary vol. 23 , ( 11 ) 1656 - 1665 .

Collaborative C, Collaborative G ( 2021 ) . Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study . Anaesthesia vol. 76 , ( 6 ) 748 - 758 .

Raj D, Nikolaidi M, Garces I, Lorizio D, Castro NM, Caiafa SG, Moore K, Brown NF et al. ( 2021 ) . CEACAM7 Is an Effective Target for CAR T-cell Therapy of Pancreatic Ductal Adenocarcinoma . Clinical Cancer Research vol. 27 , ( 5 ) 1538 - 1552 .

Adams SD, Csere J, D’angelo G, Carter EP, Romao M, Arnandis T, Dodel M, Kocher HM et al. ( 2021 ) . Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption . Current Biology vol. 31 , ( 7 ) 1403 - 1416.e7 .

Sivapalan L, Thorn G, Gadaleta E, Kocher H, Ross-Adams H, Chelala C ( 2021 ) . Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer .

Borakati A, Stasinos K, Ullah D, Chelala C, Kocher H ( 2021 ) . Effect of Diabetes Mellitus on Survival in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-analysis . Hepato Pancreato Biliary vol. 23 , s682 - s683 .

Ilyas M, Stasinos K, Zardab M, Taha A, Banerjee A, Kocher H ( 2021 ) . Study of a rare benign gangliocytic paraganglioma within the ampulla of vater . Hepato Pancreato Biliary vol. 23 , s332 - s333 .

Sivapalan L, Kocher HM, Ross-Adams H, Chelala C ( 2020 ) . Molecular profiling of ctDNA in pancreatic cancer: Opportunities and challenges for clinical application . Pancreatology vol. 21 , ( 2 ) 363 - 378 .

Dutton J, Zardab M, De Braal VJF, Hariharan D, MacDonald N, Hallworth S, Hutchins R, Bhattacharya S et al. ( 2021 ) . The accuracy of pre-operative (P)-POSSUM scoring and cardiopulmonary exercise testing in predicting morbidity and mortality after pancreatic and liver surgery: A systematic review . Annals of Medicine and Surgery . vol. 62 , 1 - 9 .

Debernardi S, O’Brien H, Algahmdi AS, Malats N, Stewart GD, Plješa-Ercegovac M, Costello E, Greenhalf W et al. ( 2020 ) . A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case–control study . PLOS Medicine vol. 17 , ( 12 )

Abu Dayem Ullah, Kocher H, Chelala C ( 2020 ) . COVID-19 in patients with hepatobiliary and pancreatic diseases in East London: a single-centre cohort study . Pancreatology vol. 20 , ( 8 )

Ullah D, Kocher H, Chelala C ( 2020 ) . Data integration for patient benefit . Pancreatology vol. 20 , ( 8 )

Gupta P, Pérez-Mancera PA, Kocher H, Nisbet A, Schettino G, Velliou EG ( 2020 ) . ON THE DEVELOPMENT OF A BIOINSPIRED, BIOMIMETIC PANCREATIC CANCER MODEL: ENGINEERING A HYBRID SCAFFOLD ASSISTED IN VITRO MULTICELLULAR MODEL OF PANCREATIC CANCER . Pancreatology vol. 20 , ( 8 )

Basu B, Gopinathan A, Bax L, Machin A, Qian W, Godfrey E, Brais R, Whitley S et al. ( 2020 ) . Pancreatic Resectability in Cancers with Known Limited Extension (PRICKLE) – a single-arm phase 2a study of gemcitabine (Gem) plus Nab-paclitaxel (NabP) for borderline (un)resectable pancreatic ductal adenocarcinoma (BrPDAC) . Pancreatology vol. 20 , ( 8 ) e3 - e4 .

Kocher HM, Basu B, Froeling FE, Sarker D, Slater S, Carlin D, deSouza NM, De Paepe KN et al. ( 2020 ) . STARPAC clinical trial . Pancreatology vol. 20 , ( 8 )

Imrali A, Hughes CS, Coetzee AS, Delvecchio FR, Saad A, Roberts R, Chelala C, ChinAleong J et al. ( 2020 ) . Validation of a Novel, Flash‐Freezing Method: Aluminum Platform . Current Protocols Essential Laboratory Techniques vol. 21 , ( 1 )

Coetzee AS, Carter EP, Milton CI, Heward JA, Uluyur F, Miao J, Mardakheh FK, Wang Y et al. ( 2020 ) . Targeting FGFR signalling to disrupt cellular cross-talk in pancreatic cancer . Pancreatology vol. 20 , ( 8 ) e19 - e19 .

Glasbey JC, Omar O, Nepogodiev D, Minaya-Bravo A, Bankhead-Kendall BK, Fiore M, Futaba K, Gabre-Kidan A et al. ( 2020 ) . Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic . British Journal of Surgery vol. 108 , ( 1 ) 88 - 96 .

Nowinski S, Cross W, Mossner M, Cresswell G, Banerjee A, Williams M, Gay L, Baker A-M et al. ( 2020 ) . Abstract PR06: Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer . Cancer Research . vol. 80 , pr06 - pr06 .

Kocher HM, Yip VS, Abraham AT ( 2020 ) . Biliary Tract Cancer . Treatment of Cancer , Taylor & Francis

Glasbey JC, Nepogodiev D, Simoes J, Omar O, Li E, Venn ML, CovidSurg Collaborative ( 2020 ) . Elective cancer surgery in COVID-19 free surgical pathways during the SARS-CoV-2 pandemic: An international, multi-centre, comparative cohort study . Journal of Clinical Oncology vol. 38 ,

Glasbey JC, Nepogodiev D, Omar O, Simoes JFF, Ademuyiwa A, Fiore M, Minaya-Bravo A, Shaw R et al. ( 2020 ) . Delaying surgery for patients with a previous SARS-CoV-2 infection . British Journal of Surgery

Kocher HM, Basu B, Froeling FEM, Sarker D, Slater S, Carlin D, deSouza NM, De Paepe KN et al. ( 2020 ) . Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer . Nature Communications vol. 11 , ( 1 )

Abu Z M Dayem Ullah, Sivapalan L, Kocher HM, Chelala C ( 2020 ) . COVID-19 in patients with hepatobiliary and pancreatic diseases: A single-centre cross-sectional study in East London .

Daulton E, Wicaksono AN, Tiele A, Kocher HM, Debernardi S, Crnogorac-Jurcevic T, Covington JA ( 2020 ) . Volatile organic compounds (VOCs) for the non-invasive detection of pancreatic cancer from urine . Talanta vol. 221 ,

Adams SD, Csere J, D’angelo G, Carter EP, Arnandis T, Dodel M, Kocher H, Grose R et al. ( 2020 ) . Centrosome amplification mediates small extracellular vesicles secretion via lysosome disruption .

Hughes CS, ChinAleong J-A, Kocher HM ( 2020 ) . CRABP2 and FABP5 expression levels in diseased and normal pancreas . Annals of Diagnostic Pathology vol. 47 ,

Passman AM, Haughey MJ, Carlotti E, Williams M, Cereser B, Russo FP, Hoare M, Kocher H et al. ( 2020 ) . 450 CLONAL DYNAMICS AND CELL-OF-ORIGIN OF NORMAL HEPATOCYTE EXPANSIONS IN HOMEOSTATIC HUMAN LIVERS AND THEIR ASSOCIATION WITH THE BILIARY EPITHELIUM . Gastroenterology vol. 158 , ( 6 ) s - 1276 .

Passman AM, Haughey MJ, Carlotti E, Williams M, Cereser B, Russo FP, Hoare M, Kocher H et al. ( 2020 ) . CLONAL DYNAMICS AND CELL-OF-ORIGIN OF NORMAL HEPATOCYTE EXPANSIONS IN HOMEOSTATIC HUMAN LIVERS AND THEIR ASSOCIATION WITH THE BILIARY EPITHELIUM . GASTROENTEROLOGY . Conference: AACR vol. 158 , S1276 - S1276 .

Gupta P, Pérez-Mancera PA, Kocher H, Nisbet A, Schettino G, Velliou EG ( 2020 ) . A Novel Scaffold-Based Hybrid Multicellular Model for Pancreatic Ductal Adenocarcinoma—Toward a Better Mimicry of the in vivo Tumor Microenvironment . Frontiers in Bioengineering and Biotechnology vol. 8 ,

Cross W, Mossner M, Nowinski S, Cresswell G, Banerjee A, Williams M, Gay L, Baker A-M et al. ( 2020 ) . Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer .

Schilling K, Larner F, Saad A, Roberts R, Kocher HM, Blyuss O, Halliday AN, Crnogorac-Jurcevic T ( 2020 ) . Urine metallomics signature as an indicator of pancreatic cancer . Metallomics: integrated biometal science

Steins A, van Mackelenbergh MG, van der Zalm AP, Klaassen R, Serrels B, Goris SG, Kocher HM, Waasdorp C et al. ( 2020 ) . High‐grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF‐1 . EMBO Reports vol. 21 , ( 5 )

Munasinghe A, Malik K, Mohamedi F, Moaraf S, Kocher H, Jones L, Hill NJ ( 2020 ) . Fibronectin acts as a molecular switch to determine SPARC function in pancreatic cancer . Cancer Letters vol. 477 , 88 - 96 .

Coetzee A ( 2019 ) . Targeting FGFR signalling to disrupt cellular cross-talk in pancreatic cancer .

Dominguez-Munoz JE, Drewes AM, Lindkvist B, Ewald N, Czakó L, Rosendahl J, Löhr JM, Löhr M et al. ( 2019 ) . Corrigendum to “Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis” [Pancreatology 18(8) (2018) 847–854] . Pancreatology vol. 20 , ( 1 )

Kocher HM, Basu B, Froeling FEM, Sarker D, Slater S, Carlin D, Coetzee C, de Souza N et al. ( 2019 ) . 700P STAR-PAC: Phase I clinical trial repurposing all trans retinoic acid (ATRA) as stromal targeting agent in a novel drug combination for pancreatic cancer . Annals of Oncology vol. 30 ,

Brodie B, Kocher HM ( 2019 ) . Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection . BJS Open vol. 3 , ( 6 ) 735 - 742 .

Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB et al. ( 2019 ) . The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy . The Journal of Pathology vol. 249 , ( 3 ) 332 - 342 .

Poudel P, Neuzillet C, Kocher H, Sadanandam A ( 2019 ) . Abstract 3094: Reclassification of pancreatic adenocarcinoma with distinct fibroblast and immune characteristics and therapeutic targets . Conference: Clinical Research (Excluding Clinical Trials)3094 - 3094 .

Goulart MR, Watt J, Siddique I, Lawor R, Dowe T, Bhattacharya S, Crnogorac-Jurcevic T, Allavena P et al. ( 2019 ) . Abstract 4892: Pentraxin 3: A stromal derived diagnostic biomarker for pancreatic ductal adenocarcinoma . Cancer Research . vol. 79 , 4892 - 4892 .

Coetzee A, Carter E, Heward J, Mardakheh F, Grose R, Kocher H ( 2019 ) . Abstract 5170: Targeting FGFR signaling to disrupt cellular cross-talk in pancreatic cancer . Cancer Research . vol. 79 , 5170 - 5170 .

North B, Kocher HM, Sasieni P ( 2019 ) . A new pragmatic design for dose escalation in phase 1 clinical trials using an adaptive continual reassessment method . BMC Cancer vol. 19 , ( 1 )

Neuzillet C, Nicolle R, Tijeras-Raballand A, Hilmi M, Richon S, Brunel A, Samain R, Sadanandam A et al. ( 2019 ) . Heterogeneity of human pancreatic adenocarcinoma (PDAC) cancer-associated fibroblasts (CAF): subtype-A (periostin-positive) CAF is associated with aggressive tumor features and is an early CAF . Pancreatology vol. 19 ,

Roy M, Tun JK, Banerjee A, Mohandas S, Abraham AT, Hutchins RR, Bhattacharya S, Renfrew I et al. ( 2019 ) . Factors affecting length of stay after percutaneous biliary interventions . British Journal of Radiology vol. 92 , ( 1096 )

Neuzillet C, Tijeras‐Raballand A, Ragulan C, Cros J, Patil Y, Martinet M, Erkan M, Kleeff J et al. ( 2019 ) . Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma . The Journal of Pathology vol. 248 , ( 1 ) 51 - 65 .

Coetzee A, Grose R, Kocher H ( 2019 ) . Pancreatic Cancer Organotypic Models . vol. 430 , 183 - 198 .

Househam J, Heide T, Spiteri I, Kimberley C, Nichol D, Lakatos E, Cross WC, Cresswell G et al. ( 2019 ) . Clonal Evolution of Alternative Splicing in Colorectal Cancer at Single Gland Resolution . JOURNAL OF PATHOLOGY . vol. 248 , S14 - S14 .

Spear S, Candido JB, McDermott JR, Ghirelli C, Maniati E, Beers SA, Balkwill FR, Kocher HM et al. ( 2019 ) . Discrepancies in the tumor microenvironment of spontaneous and orthotopic murine models of pancreatic cancer uncover a new immunostimulatory phenotype for B cells . Frontiers in Immunology vol. 10 , ( MAR )

Kocher HM, Basu B, Froeling FEM, Sarker D, Slater S, Carlin D, Coetzee C, de Souza N et al. ( 2019 ) . STAR-PAC: Phase I clinical trial repurposing all trans retinoic acid (ATRA) as stromal targeting agent in a novel drug combination for pancreatic cancer . ANNALS OF ONCOLOGY . vol. 30 ,

Passman A, Williams M, Carlotti E, Cereser B, Hoare M, Russo F, Kocher HM, Chin-Aleong J et al. ( 2019 ) . The Cell of Origin of Normal Human Hepatocytes has a Common Ancestor with Biliary Epithelium and Hepatocyte Clonal Expansions Arise from the Portal Tract and Drift to the Central Vein . JOURNAL OF PATHOLOGY . vol. 249 , S16 - S16 .

de Braal V, Dutton J, Hariharan D, MacDonald N, Hallworth S, Kocher H, Hutchins R, Imtiaz H et al. ( 2019 ) . The use of POSSUM scoring and Cardiopulmonary exercise test are limited in predicting major complications after liver and pancreas surgery . BRITISH JOURNAL OF SURGERY . vol. 106 , 21 - 21 .

Veenstra VL, Damhofer H, Waasdorp C, van Rijssen LB, van de Vijver MJ, Dijk F, Wilmink HW, Besselink MG et al. ( 2018 ) . ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy . Oncogenesis vol. 7 , ( 11 )

McCluney S, Jhumka N, Hutchins R, Abraham A, Bhattacharya S, Kocher H ( 2018 ) . 16. The Prognostic Significance of the Neutrophil:lymphocyte Ratio in Predicting Complications Following Hepatic Resection for Cholangiocarcinoma and Gallbladder Cancer . European Journal of Surgical Oncology vol. 44 , ( 11 )

Roy M, Ban EJ, Mohandas S, Mownah O, Banerjee A, Kocher H, Bhattacharya S, Hutchins R ( 2018 ) . Re: Comparison of lipase and amylase for diagnosing post‐operative pancreatic fistulae . ANZ Journal of Surgery vol. 88 , ( 11 ) 1213 - 1214 .

Dominguez-Munoz JE, Drewes AM, Lindkvist B, Ewald N, Czakó L, Rosendahl J, Löhr JM, Löhr M et al. ( 2018 ) . Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis . Pancreatology vol. 18 , ( 8 ) 847 - 854 .

Roy M, Ban E, Mohandas S, Mownah O, Banerjee A, Valente R, Abraham A, Kocher H et al. ( 2018 ) . Comparison of drain fluid lipase with drain fluid amylase in the context of post-operative pancreatic fistula . Hepato Pancreato Biliary vol. 20 ,

Raj D, Yang M-H, Rodgers D, Hampton EN, Begum J, Mustafa A, Lorizio D, Garces I et al. ( 2018 ) . Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma . Gut vol. 68 , ( 6 )

McCluney SJ, Giakoustidis AA, Segler A, Bissel J, Miller RL, Valente R, Hutchins RR, Abraham A et al. ( 2018 ) . Predicting complications in hepatic resection for colorectal liver metastasis: the lymphocyte‐to‐monocyte ratio . ANZ Journal of Surgery vol. 88 , ( 11 ) e782 - e786 .

McCluney S, Giakoustidis A, Segler A, Bissel J, Valente R, Hutchins R, Abraham A, Bhattacharya S et al. ( 2018 ) . Neutrophil:Lymphocyte ratio: Can we predict complications following hepatic resection for colorectal liver metastasis? . European Journal of Surgical Oncology vol. 44 , s2 - s3 .

McCluney SJ, Giakoustidis A, Segler A, Bissel J, Valente R, Hutchins RR, Abraham AT, Bhattacharya S et al. ( 2018 ) . Neutrophil: Lymphocyte ratio as a method of predicting complications following hepatic resection for colorectal liver metastasis . Journal of Surgical Oncology vol. 117 , ( 5 ) 1058 - 1065 .

Ghaneh P, Hanson R, Titman A, Lancaster G, Plumpton C, Lloyd-Williams H, Yeo ST, Edwards RT et al. ( 2018 ) . PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer . Health Technology Assessment vol. 22 , ( 7 ) 1 - 114 .

McCluney S, Wijesuriya N, Sheshappanavar V, Chin‐Aleong J, Feakins R, Hutchins R, Abraham A, Bhattacharya S et al. ( 2018 ) . Solid pseudopapillary tumour of the pancreas: clinicopathological analysis . ANZ Journal of Surgery vol. 88 , ( 9 ) 891 - 895 .

Roy M, Tun J, Banerjee A, Mohandas S, Fottheringham T, Kocher H ( 2018 ) . Factors affecting length of stay and mortality after percutaneous transhepatic biliary intervention . BRITISH JOURNAL OF SURGERY . vol. 105 , 133 - 133 .

McCluney S, Giakoustidis A, Segler A, Bissel J, Miller R, Valente R, Hutchins R, Abraham A et al. ( 2018 ) . The utility of the Lymphocyte: Monocyte ratio in predicting complications following hepatic resection for colorectal liver metastasis . BRITISH JOURNAL OF SURGERY . vol. 105 , 11 - 12 .

Arumugam P, Bhattacharya S, Chin-Aleong J, Capaso M, Hemant MK ( 2017 ) . Corrigendum to “Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma” [Pancreatology 17 (2017) 295–302] . Pancreatology vol. 18 , ( 1 )

Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al. ( 2017 ) . Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers . Cancer Discov

CRNOGORAC-JURCEVIC T ( 2017 ) . Non-invasive Diagnosis of Pancreatic Cancer Through Detection of Volatile Organic Compounds in Urine . Gastroenterology

McCluney S, Giakoustidis A, Segler A, Bissel J, Valente R, Hutchins R, Abraham A, Bhattacharya S et al. ( 2017 ) . 901. Neutrophil:Lymphocyte ratio: Can we predict complications following hepatic resection for colorectal liver metastasis? . European Journal of Surgical Oncology vol. 43 , ( 11 ) 2203 - 2204 .

Marzec J, Dayem Ullah AZ, Pirrò S, Gadaleta E, Crnogorac-Jurcevic T, Lemoine NR, Kocher HM, Chelala C ( 2017 ) . The Pancreatic Expression Database: 2018 update . Nucleic Acids Res vol. 46 , ( D1 ) D1107 - D1110 .

Neuzillet C, de Mestier L, Rousseau B, Mir O, Hebbar M, Kocher HM, Ruszniewski P, Tournigand C ( 2017 ) . Unravelling the pharmacologic opportunities and future directions for targeted therapies in gastro-intestinal cancers part 2: Neuroendocrine tumours, hepatocellular carcinoma, and gastro-intestinal stromal tumours . Pharmacology & Therapeutics vol. 181 , 49 - 75 .

Veenstra VL, Damhofer H, Waasdorp C, Steins A, Kocher HM, Medema JP, van Laarhoven HW, Bijlsma MF ( 2017 ) . Stromal SPOCK1 supports invasive pancreatic cancer growth . Mol Oncol vol. 11 , ( 8 ) 1050 - 1064 .

Löhr JM, Dominguez‐Munoz E, Rosendahl J, Besselink M, Mayerle J, Lerch MM, Haas S, Akisik F et al. ( 2017 ) . United European Gastroenterology evidence‐based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU) . United European Gastroenterology Journal vol. 5 , ( 2 ) 153 - 199 .

King H, Thillai K, Whale A, Arumugam P, Eldaly H, Kocher HM, Wells CM ( 2017 ) . PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration . Sci Rep vol. 7 , 42575 - 42575 .

Neuzillet C, Rousseau B, Kocher H, Bourget P, Tournigand C ( 2017 ) . Unravelling the pharmacologic opportunities and future directions for targeted therapies in gastro-intestinal cancers Part 1: GI carcinomas . Pharmacology & Therapeutics vol. 174 , 145 - 172 .

Arumugam P, Bhattacharya S, Chin-Aleong J, Capaso M, Kocher HM ( 2017 ) . Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma . Pancreatology vol. 17 , ( 2 ) 295 - 302 .

McCluney S, Giakoustidis A, Segler A, Bissel J, Valente R, Hutchins R, Abraham A, Bhattacharya S et al. ( 2017 ) . Hepatic resection for colorectal liver metastasis: can we predict complications using the neutrophil: lymphocyte ratio? . BRITISH JOURNAL OF SURGERY . vol. 104 , 21 - 21 .

Phadnis S, Neuzillet C, Vernerey D, Jeyarajah A, Kocher H, Brockbank E ( 2017 ) . SURGICAL CYTOREDUCTION OF THE UPPER ABDOMEN IN GYNAECOLOGICAL CANCER: AN EXPERIENCE OF ADDITIONAL SKILL ACQUISITION BY THE GYNAECOLOGY ONCOLOGY TEAM FROM COLLABORATION WITH HEPATOBILIARY SURGEONS . INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER . vol. 27 , 1630 - 1630 .

McCluney SJ, Jamalfar A, Abraham AT, Kocher HM ( 2017 ) . Surgical referrals at a major trauma centre: an unsustainable future? . BRITISH JOURNAL OF SURGERY . vol. 104 , 41 - 41 .

Vallath S, Reader C, Morton J, Sansom O, Evans J, Biankin A, Barry ST, Kocher H et al. ( 2016 ) . Abstract B53: The integrin αvβ6 is a promising therapeutic target for treating PDAC . Cancer Research . vol. 76 , b53 - b53 .

McCluney SJ, Balarajah V, Giakoustidis A, Chin-Aleong J, Lovett B, Kocher HM ( 2016 ) . Intussuscepting Ampullary Adenoma: An Unusual Cause of Gastric Outlet Obstruction Leading to Cavitating Lung Lesions . Case Reports in Gastroenterology vol. 10 , ( 3 ) 545 - 552 .

Solaini L, Atmaja BT, Arumugam P, Hutchins RR, Abraham AT, Bhattacharya S, Kocher HM ( 2016 ) . The role of perioperative inflammatory-based prognostic systems in patients with colorectal liver metastases undergoing surgery. A cohort study . International Journal of Surgery vol. 36 , ( Pt A ) 8 - 12 .

Balarajah V, Neuzillet C, Kocher HM ( 2016 ) . Targeting pancreatic stellate cells to improve pancreatic cancer radiosensitivity . Translational Cancer Research vol. 5 , ( S4 ) s730 - s737 .

Kadaba RS, Bowers KA, Khorsandi S, Hutchins RR, Abraham AT, Sarker S-J, Bhattacharya S, Kocher HM ( 2016 ) . Complications of biliary-enteric anastomoses . Annals of The Royal College of Surgeons of England vol. 99 , ( 3 ) 210 - 215 .

Balarajah V, Ambily A, Dayem Ullah AZ, Imrali A, Dowe T, Al-Sarireh B, Abu Hilal M, Davidson BR et al. ( 2016 ) . Pancreatic cancer tissue banks: where are we heading? . Future Oncol vol. 12 , ( 23 ) 2661 - 2663 .

Arumugam P, Balarajah V, Watt J, Abraham AT, Bhattacharya S, Kocher HM ( 2016 ) . Role of laparoscopy in hepatobiliary malignancies . Indian J Med Res vol. 143 , ( 4 ) 414 - 419 .

GROSE RP, Dawkins JBN, Wang J, maniati, heward, koniali, kocher, martin et al. ( 2016 ) . Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma . Cancer Research

Carapuça EF, Gemenetzidis E, Feig C, Bapiro TE, Williams MD, Wilson AS, Delvecchio FR, Arumugam P et al. ( 2016 ) . Developing drug combinations to co-target pancreatic cancer and its supporting stroma . Pancreatology vol. 16 , ( 3 )

Man YKS, Pantelidou C, Blázquez-Moreno A, Coughlan L, Marshall J, Kocher H, Halldén G ( 2016 ) . Modifying oncolytic viral therapy for pancreatic cancer . Pancreatology vol. 16 , ( 3 )

Ghaneh P, Wong WL, Titman A, Plumpton C, Vinjamuri S, Johnson C, Abu Hilal M, Higginson A et al. ( 2016 ) . PET-PANC: Multi-centre prospective diagnostic accuracy and clinical value study of PET/CT in the diagnosis and management of pancreatic cancer . Pancreatology vol. 16 , ( 3 )

Di Maggio F, Arumugam P, Delvecchio FR, Batista S, Lechertier T, Hodivala-Dilke K, Kocher HM ( 2016 ) . Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma . Pancreatology

Kocher H, Propper DJ, Alabaf S, Mousa K, North B, Papoutsaki V, Smith D-M, Ambily A et al. ( 2016 ) . STAR_PAC: A Phase 1B study repurposing ATRA as stromal targeting agent along with gemcitabine and nab¬Paclitaxel for pancreatic cancer . Pancreatology vol. 16 , ( 3 ) s4 - s5 .

Marshall J, Vallath S, Reader C, Morton J, Sansom O, Evans TRJ, Biankin A, Kocher HM ( 2016 ) . The integrin αvβ6 is a promising therapeutic target for treating PDAC . Pancreatology vol. 16 , ( 3 )

Hariharan D, Junaid H, Bhattacharya S, Abraham A, Hutchins R, Preston S, Woodland P, Aleong JC et al. ( 2016 ) . The role of EUS guided sampling in the management of solid, cystic and mixed lesions affecting the pancreas . Pancreatology vol. 16 , ( 3 )

Hariharan D, Junaid H, Renfrew I, Low D, Fotheringham T, Bhattacharya S, Abraham A, Hutchins R et al. ( 2016 ) . The role of EUS sampling in the management of all lesions affecting the pancreas . Pancreatology vol. 16 , ( 3 ) s7 - s8 .

Hariharan D, Junaid H, Renfrew I, Low D, Fotheringham T, Bhattacharya S, Abraham A, Hutchins R et al. ( 2016 ) . The role of image guided sampling in the management of solid, cystic and mixed lesions affecting the pancreas . Pancreatology vol. 16 , ( 3 )

Carapuça EF, Gemenetzidis E, Feig C, Bapiro TE, Williams MD, Wilson AS, Delvecchio FR, Arumugam P et al. ( 2016 ) . Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma . Journal of Pathology vol. 239 , ( 3 ) 286 - 296 .

Ghaneh P, Wong WL, Titman A, Plumpton C, Vinjamuri S, Johnson C, Abu Hilal M, Higginson A et al. ( 2016 ) . PET-PANC: Multi-centre prospective diagnostic accuracy and clinical value trial of FDG PET/CT in the diagnosis and management of suspected pancreatic cancer . Journal of Clinical Oncology . vol. 34 , 4008 - 4008 .

Arumugam P, Fletcher N, Kyriakides C, Mears L, Kocher HM ( 2016 ) . Lymphoepithelial Cyst of the Pancreas . Case Reports in Gastroenterology vol. 10 , ( 1 ) 186 - 197 .

Gani MA, Watt J, Solaini L, Arumugam P, Hutchins R, Abraham A, Bhattacharya S, Kocher H ( 2016 ) . Low serum albumin and positive lymph nodes predict poor outcome in cholangiocarcinoma . Hepato Pancreato Biliary vol. 18 , e672 - e673 .

Hariharan D, Junaid H, Bhattacharya S, Abraham A, Hutchins R, Preston S, Woodland P, Chin-Aleong J et al. ( 2016 ) . Accuracy of EUS/FNAC in the management of solid, cystic and mixed lesions affecting the pancreas . BRITISH JOURNAL OF SURGERY . vol. 103 , 8 - 8 .

Pantelidou C, Man YKS, Coughlan L, Marshall J, Kocher H, Hallden G ( 2016 ) . Oncolytic adenoviral mutants deleted in the anti-apoptotic E1B19K gene sensitize pancreatic cancer cells to drug-induced DNA damage . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 38 , S58 - S58 .

Hartmann S, Kocher H ( 2015 ) . Application of Mechanistic Pharmacokinetic– Pharmacodynamic Modeling toward the Development of Biologics . Developability of Biotherapeutics , Taylor & Francis

Coupland VH, Konfortion J, Jack RH, Allum W, Kocher HM, Riaz SP, Lüchtenborg M, Møller H ( 2015 ) . Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005–2009 . European Journal of Surgical Oncology vol. 42 , ( 2 ) 190 - 196 .

Debernardi S, Massat NJ, Radon TP, Sangaralingam A, Banissi A, Ennis DP, Dowe T, Chelala C et al. ( 2015 ) . Noninvasive urinary miRNA biomarkers for early detection of pancreatic adenocarcinoma . American Journal of Cancer Research vol. 5 , ( 11 ) 3455 - 3466 .

Radon TP, Massat NJ, Jones R, Alrawashdeh W, Dumartin L, Ennis D, Duffy SW, Kocher HM et al. ( 2015 ) . Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma . Clinical Cancer Research vol. 21 , ( 15 ) 3512 - 3521 .

Watt J, Siddique I, Dowe T, Crnogorac-Jurcevic T, Bhattacharya S, Allavena P, Kocher HM ( 2015 ) . Abstract A56: The role of Pentraxin 3 (PTX3) in pancreatic ductal adenocarcinoma . Conference: Inflammation/Stromaa56 - a56 .

Carapuça EF, Gemenetzidis E, Feig C, Tuveson D, Kocher H ( 2015 ) . Abstract B72: Developing drug combinations to co-target pancreatic cancer and its supporting stroma . Conference: New Therapiesb72 - b72 .

Reader CS, Vallath S, Morton J, Steele C, Kocher HM, Keyse SM, Sansom O, Marshall JF ( 2015 ) . Abstract B87: Cell lines generated from PDAC transgenic mice reveal integrin αvβ6 modifies the invasive phenotype of pancreatic cancer . Conference: New Therapiesb87 - b87 .

Viloria K, Ryall C, Dandagama A, Asher S, Lhaf F, King A, Jones P, Kocher H et al. ( 2015 ) . Creating a 3D matricellular environment to promote islet expansion for diabetes therapy – the role of SPARC family proteins . The FASEB Journal . vol. 29 ,

Solaini L, Jamieson NB, Metcalfe M, Abu Hilal M, Soonawalla Z, Davidson BR, McKay C, Kocher HM et al. ( 2015 ) . Outcome after surgical resection for duodenal adenocarcinoma in the UK . British Journal of Surgery vol. 102 , ( 6 ) 676 - 681 .

Solaini L, Atmaja BT, Watt J, Arumugam P, Hutchins RR, Abraham AT, Bhattacharya S, Kocher HM ( 2015 ) . Limited utility of inflammatory markers in the early detection of postoperative inflammatory complications after pancreatic resection: Cohort study and meta-analyses . International Journal of Surgery vol. 17 , 41 - 47 .

Froeling FEM, Kocher HM ( 2015 ) . Homeostatic Restoration of Desmoplastic Stroma Rather Than Its Ablation Slows Pancreatic Cancer Progression . Gastroenterology vol. 148 , ( 4 ) 849 - 850 .

Alison M, Cereser B, Kocher H, McDonald SA ( 2015 ) . Clonal analysis of the human liver reveals adaptable stem cell dynamics . HEPATOLOGY . vol. 62 , 260A - 260A .

Wong P-P, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford MRL, Scudamore CL, Cereser B, Crnogorac-Jurcevic T et al. ( 2015 ) . Dual-Action Combination Therapy Enhances Angiogenesis while Reducing Tumor Growth and Spread . Cancer Cell vol. 27 , ( 1 ) 123 - 137 .

Wong P-P, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford M, Scudamore C, Cereser B, Crnogorac-Jurcevic T et al. ( 2015 ) . NOVEL DUAL-ACTION COMBINATION THERAPY ENHANCES ANGIOGENESIS WHILST REDUCING TUMOR GROWTH AND SPREAD . JOURNAL OF VASCULAR RESEARCH . vol. 52 , 6 - 6 .

Haider S, Wang J, Nagano A, Desai A, Arumugam P, Dumartin L, Fitzgibbon J, Hagemann T et al. ( 2014 ) . A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma . Genome Medicine vol. 6 , ( 12 )

Ryall CL, Viloria K, Lhaf F, Walker AJ, King A, Jones P, Mackintosh D, McNeice R et al. ( 2014 ) . Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling . J Biol Chem vol. 289 , ( 44 ) 30614 - 30624 .

Kocher HM, Abraham AT, Bhattacharya S ( 2014 ) . Biliary tract cancer . Treatment of Cancer , Taylor & Francis

Petty RD, Brand G, Nanthakumuran S ( 2014 ) . Gastric cancer . Treatment of Cancer , Taylor & Francis

Sunkel-Laing B, Kalam A, Renfrew I, Mears L, Kocher HM ( 2014 ) . Repeated Negative Biopsies in Isolated High-Grade Cystic Duct Dysplasia with Progression to Adenocarcinoma . Case Reports in Gastroenterology vol. 8 , ( 3 ) 304 - 309 .

Coleman SJ, Bruce C, Chioni A-M, Kocher HM, Grose RP ( 2014 ) . The ins and outs of fibroblast growth factor receptor signalling . Clin Sci (Lond) vol. 127 , ( 4 ) 217 - 231 .

Konfortion J, Coupland VH, Kocher HM, Allum W, Grocock MJ, Jack RH ( 2014 ) . Time and deprivation trends in incidence of primary liver cancer subtypes in England . J Eval Clin Pract vol. 20 , ( 4 ) 498 - 504 .

Coleman SJ, Watt J, Arumugam P, Solaini L, Carapuca E, Ghallab M, Grose RP, Kocher HM ( 2014 ) . Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation . World J Gastroenterol vol. 20 , ( 26 ) 8471 - 8481 .

Gill RMS, Michael A, Westley L, Kocher HM, Murphy JI, Dhoot GK ( 2014 ) . SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression . Experimental Cell Research vol. 324 , ( 2 ) 157 - 171 .

Gill RMS, Michael A, Westley L, Kocher HM, Murphy JI, Dhoot GK ( 2014 ) . SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression . Exp Cell Res vol. 324 , ( 2 ) 157 - 171 .

Carapuca E, Gemenetzidis E, Feig C, Tuveson D, Kocher H ( 2014 ) . Developing drug combinations to co-target pancreatic cancer and its supporting stroma . Pancreatology vol. 14 , ( 3 )

Siddiqui I, Marchesi F, Erreni M, Pesce S, Mantovani A, Kocher H, Allavena P ( 2014 ) . Inflammation triggered by oncogenic KRasG12V in pancreatic tumor cells . Pancreatology vol. 14 , ( 3 )

Solaini L, Sharma A, Watt J, Iosifidou S, Chin Aleong J-A, Kocher HM ( 2014 ) . Predictive factors for incidental gallbladder dysplasia and carcinoma . J Surg Res vol. 189 , ( 1 ) 17 - 21 .

Watt J, Siddique I, Dowe T, Crnogorac-Jurcevic T, Bhattacharya S, Allavena P, Kocher H ( 2014 ) . The role of pentraxin 3 in pancreatic ductal adenocarcinoma . Pancreatology vol. 14 , ( 3 )

Coleman SJ, Grose RP, Kocher HM ( 2014 ) . Fibroblast growth factor family as a potential target in the treatment of hepatocellular carcinoma . Journal of Hepatocellular Carcinoma vol. Volume 1 , 43 - 54 .

Watt J, Siddiqui I, Radon T, Dowe T, Crnogorac-Jurcevic T, Allavena P, Kocher H ( 2014 ) . Sa1371 Pentraxin3 Is a Stromal Biomarker in Pancreatic Ductal Adenocarcinoma . Gastroenterology vol. 146 , ( 5 ) s - 276 .

Carapuça E, Gemenetzidis E, Feig C, Tuveson DA, Kocher H ( 2014 ) . Su1907 Developing Drug Combinations to Co-Target Pancreatic Cancer and Its Supporting Stroma . Gastroenterology vol. 146 , ( 5 ) s - 498 .

Kadaba R, Birke H, DiMaggio F, Wang J, Chelala C, Sasieni P, Kocher HM ( 2012 ) . Abstract B100: The proportion of pancreatic stellate cells plays a critical role in modulating pancreatic cancer cell behavior . Conference: Tumor Biologyb100 - b100 .

Vallath S, Gadaletta E, Chelala C, Scarpa A, Hart IR, Kocher HM, Marshall JF ( 2012 ) . Abstract B42: Toward targeting integrin αvβ6 for the therapy of pancreatic cancer . Conference: Therapyb42 - b42 .

Coleman S, Kocher H, Grose R ( 2012 ) . Abstract B65: Investigating the role of nuclear FGF2 signaling in pancreatic cancer . Conference: Tumor Biologyb65 - b65 .

Ghallab MA, Guglielmo R, Escrig IS, Hart IR, Bhattacharya S, Kocher HM ( 2012 ) . Abstract B80: Targeting pancreatic cancer stroma with histone deacetylase inhibitors . Conference: Tumor Biologyb80 - b80 .

Coleman SJ, Chioni A-M, Ghallab M, Anderson RK, Lemoine NR, Kocher HM, Grose RP ( 2014 ) . Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion . EMBO Mol Med vol. 6 , ( 4 ) 467 - 481 .

Coleman S, Chioni A-M, Ghallab M, Anderson R, Lemoine N, Kocher H, Grose R ( 2014 ) . Nuclear FGFR signalling as a driving force in pancreatic cancer . Pancreatology vol. 14 , ( 2 )

Kocher HM ( 2014 ) . Paget Lecture: Introduction . Pancreatology vol. 14 , ( 2 )

Vyas S, Markar S, Partelli S, Fotheringham T, Low D, Imber C, Malago M, Kocher HM ( 2014 ) . Portal vein embolization and ligation for extended hepatectomy . Indian J Surg Oncol vol. 5 , ( 1 ) 30 - 42 .

Vallath S, Scarpa A, Weinreb P, Violette S, Steele C, Morton J, Sansom O, Davies J et al. ( 2014 ) . The integrin αvβ6 is a promising target for the therapy of PDAC: toward phase I trials . Pancreatology vol. 14 , ( 2 )

Milne R, La Vecchia C, Van Steen K, Hahn S, Buchholz M, Costello E, Esposito I, Hoheisel JD et al. ( 2014 ) . EU Pancreas: An Integrated European Platform for Pancreas Cancer Research - from Basic Science to Clinical and Public Health Interventions for a Rare Disease . Public Health Genomics vol. 16 , ( 6 ) 305 - 312 .

Watt J, Siddique I, Dowe T, Crnogorac-Jurcevic T, Allavena P, Kocher H ( 2014 ) . Role of PTX3 in pancreatic cancer . The Lancet vol. 383 ,

Carapuca E, Gemenetzidis E, Feig C, Tuveson DA, Kocher H ( 2014 ) . Developing Drug Combinations to Co-Target Pancreatic Cancer and Its Supporting Stroma . GASTROENTEROLOGY . vol. 146 , S498 - S498 .

Watt J, Siddiqui I, Radon T, Dowe T, Crnogorac-Jurcevic T, Allavena P, Kocher H ( 2014 ) . Pentraxin3 Is a Stromal Biomarker in Pancreatic Ductal Adenocarcinoma . GASTROENTEROLOGY . vol. 146 , S276 - S276 .

Solaini L, Jamieson NB, Tamburrini R, Spoletini G, Abu Hilal M, Johnson CD, Soonawalla Z, Davidson B et al. ( 2014 ) . UK Multicentre Surgical Experience With Primary Duodenal Adenocarcinoma . GASTROENTEROLOGY . vol. 146 , S334 - S334 .

Arumugam P, Partelli S, Coleman SJ, Cataldo I, Beghelli S, Bassi C, Wijesuriya N, Aleong J-AC et al. ( 2013 ) . Ezrin expression is an independent prognostic factor in gastro-intestinal cancers . J Gastrointest Surg vol. 17 , ( 12 ) 2082 - 2091 .

Gourgiotis S, Gemenetzis G, Kocher HM, Aloizos S, Salemis NS, Grammenos S ( 2013 ) . Permissive hypotension in bleeding trauma patients: helpful or not and when? . Crit Care Nurse vol. 33 , ( 6 ) 18 - 24 .

Watt J, Kocher HM ( 2013 ) . The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltration . Oncoimmunology vol. 2 , ( 12 )

Ene-Obong A, Clear AJ, Watt J, Wang J, Fatah R, Riches JC, Marshall JF, Chin-Aleong J et al. ( 2013 ) . Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma . Gastroenterology vol. 145 , ( 5 ) 1121 - 1132 .

Sharma A, Iosifidou S, Qureishi A, Solaini L, Chin Aloeng JA, Kocher H ( 2013 ) . Incidental gall bladder dysplasia and neoplasia in 21st century . Int J Surg vol. 11 , ( 8 )

Coleman S, Chioni A-M, Ghallab M, Lemoine N, Grose RP, Kocher H ( 2013 ) . 538 Nuclear Translocation of FGFR1 and FGF2 in Pancreatic Stellate Cells Is Necessary for Pancreatic Cancer Cell Invasion . Gastroenterology vol. 144 , ( 5 ) s - 98 .

Kadaba R, Birke H, Wang J, Hooper S, Andl CD, Di Maggio F, Soylu E, Ghallab M et al. ( 2013 ) . Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes . J Pathol vol. 230 , ( 1 ) 107 - 117 .

Ghallab M, Rosignoli G, Escrig IS, Bhattacharya S, Kocher H ( 2013 ) . Sa1713 Targeting Pancreatic Cancer Stroma by HDAC Inhibitors . Gastroenterology vol. 144 , ( 5 )

Jack RH, Konfortion J, Coupland VH, Kocher HM, Berry DP, Allum W, Linklater KM, Møller H ( 2013 ) . Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007 . Cancer Epidemiol vol. 37 , ( 1 ) 34 - 38 .

Ene-Obong A, Clear AJ, Ramsay AG, Kocher HM ( 2013 ) . Activated pancreatic stellate cells inhibit CD8+ infiltrate in pancreatic ductal adenocarcinoma via CXCL12 . Pancreatology vol. 13 , ( 1 )

Gabriel J, Graham TA, Kocher H, Wright NA, Alison M, McDonald SAC ( 2013 ) . Methylation Patterns of Clonally-Related Hepatocytes Provide Evidence of a Periportal Stem Cell Niche in the Normal Human Liver . JOURNAL OF PATHOLOGY . vol. 231 , 15 - 15 .

Coleman S, Chioni A-M, Ghallab M, Lemoine N, Grose RP, Kocher H ( 2013 ) . Nuclear Translocation of FGFR1 and FGF2 in Pancreatic Stellate Cells Is Necessary for Pancreatic Cancer Cell Invasion . GASTROENTEROLOGY . vol. 144 , S98 - S98 .

Coleman SJ, Chioni A-M, Ghallab M, Anderson RK, Lemoine NR, Grose RP, Kocher HM ( 2013 ) . Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells is necessary for pancreatic cancer cell invasion . Pancreatology vol. 13 , ( 1 ) e10 - e11 .

Li NF, Gemenetzidis E, Marshall FJ, Davies D, Yu Y, Frese K, Froeling FEM, Woolf AK et al. ( 2013 ) . RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells . PLoS One vol. 8 , ( 12 )

Ghallab M, Rosignoli G, Escrig IS, Bhattacharya S, Kocher H ( 2013 ) . Targeting Pancreatic Cancer Stroma by HDAC Inhibitors . GASTROENTEROLOGY . vol. 144 , S289 - S290 .

Ghallab MA, Rosignoli G, Escrig IS, Hurst HC, Hart IR, Bhattacharya S, Kocher HM ( 2013 ) . Targeting pancreatic cancer stroma by HDAC inhibitors . BRITISH JOURNAL OF SURGERY . vol. 100 , 4 - 4 .

Coward JIG, Ding N-L, Feakins R, Kocher H, Popat S, Szlosarek PW ( 2012 ) . Chemotherapy-induced bowel obstruction in small cell lung cancer: a case report . Med Oncol vol. 29 , ( 4 ) 2623 - 2625 .

Vyas S, Bent C, Partelli S, Abraham AT, Hutchins RR, Bhattacharya S, Low D, Fotheringham T et al. ( 2012 ) . Portal vein embolisation for extended hepatectomy: single-centre experience . J Gastrointest Cancer vol. 43 , ( 3 ) 413 - 419 .

Coupland VH, Kocher HM, Berry DP, Allum W, Linklater KM, Konfortion J, Møller H, Davies EA ( 2012 ) . Incidence and survival for hepatic, pancreatic and biliary cancers in England between 1998 and 2007 . Cancer Epidemiol vol. 36 , ( 4 ) e207 - e214 .

Guppy NJ, El-Bahrawy ME, Kocher HM, Fritsch K, Qureshi YA, Poulsom R, Jeffery RE, Wright NA et al. ( 2012 ) . Trefoil factor family peptides in normal and diseased human pancreas . Pancreas vol. 41 , ( 6 ) 888 - 896 .

Hariharan D, Constantinides V, Kocher HM, Tekkis PP ( 2012 ) . The role of laparoscopy and laparoscopic ultrasound in the preoperative staging of patients with resectable colorectal liver metastases: a meta-analysis . Am J Surg vol. 204 , ( 1 ) 84 - 92 .

Naidoo K, Jones R, Dmitrovic B, Wijesuriya N, Kocher H, Hart IR, Crnogorac-Jurcevic T ( 2012 ) . Proteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinoma and lymph node metastases . J Pathol vol. 226 , ( 5 ) 756 - 763 .

Lines KE, Chelala C, Dmitrovic B, Wijesuriya N, Kocher HM, Marshall JF, Crnogorac-Jurcevic T ( 2012 ) . S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells . Am J Pathol vol. 180 , ( 4 ) 1485 - 1494 .

Menne H, Köcher H ( 2012 ) . HRAC Classification of Herbicides and Resistance Development . Modern Crop Protection Compounds , Wiley

Kocher HM, Kadaba R ( 2011 ) . Chronic pancreatitis . BMJ Clin Evid vol. 2011 ,

Gadaleta E, Cutts RJ, Kelly GP, Crnogorac-Jurcevic T, Kocher HM, Lemoine NR, Chelala C ( 2011 ) . A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws . Nucleic Acids Res vol. 39 , ( 18 ) 7900 - 7907 .

Froeling FEM, Feig C, Chelala C, Dobson R, Mein CE, Tuveson DA, Clevers H, Hart IR et al. ( 2011 ) . Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression . Gastroenterology vol. 141 , ( 4 ) 1486 - 1497.14 .

Coleman SJ, Myrto-Chioni A, Grose RP, Kocher H ( 2011 ) . Investigating the Role of FGF Signaling in Pancreatic Cancer . GASTROENTEROLOGY . vol. 140 , S714 - S714 .

Froeling F, Chelala C, Clevers H, Hart I, Kocher H ( 2011 ) . Retinoic Acid-Induced Stellate Cell Quiescence Results in Sfrp4 Secretion Which Abrogates Wnt-beta-Catenin Signalling Pathway Modulating Human Pancreatic Tumour Cell Behaviour . GASTROENTEROLOGY . vol. 140 , S156 - S157 .

Kadaba R, Froeling F, Soylu E, Bhattacharya S, Hart I, Kocher H ( 2011 ) . The Ratio of Pancreatic Stellate Cells to Pancreatic Cancer Cells Plays a Critical Role in Modulating Carcinoma Cell Behaviour . GASTROENTEROLOGY . vol. 140 , S713 - S713 .

Lines KE, Audi N, Chelala C, Wijesuriya N, Kocher H, Hurst H, Crnogorac-Jurcevic T ( 2011 ) . Abstract 1537: Role of S100PBP in pancreatic adenocarcinoma . Cancer Research vol. 71 , ( 8_Supplement ) 1537 - 1537 .

Kadaba R, Bowers KA, Wijesuriya N, Preston SL, Bray GB, Kocher HM ( 2011 ) . An unusual cause of gastrointestinal bleeding: duodenal lipoma . Case Rep Gastroenterol vol. 5 , ( 1 ) 183 - 188 .

Naidoo K, Al-Rawashdeh W, Hart IR, Crnogorac-Jurcevic T, Jones R, Wijesuriya N, Kocher HM ( 2011 ) . The role of S100P expression in metastatic pancreatic ductal adenocarcinoma . CLIN EXP METASTAS vol. 28 , ( 2 ) 165 - 165 .

Soylu E, Junnarkar S, Kocher HM ( 2010 ) . Recurrent indigestion in a young adult . Case Rep Gastroenterol vol. 4 , ( 3 ) 518 - 523 .

Edling CE, Selvaggi F, Buus R, Maffucci T, Di Sebastiano P, Friess H, Innocenti P, Kocher HM et al. ( 2010 ) . Key role of phosphoinositide 3-kinase class IB in pancreatic cancer . Clin Cancer Res vol. 16 , ( 20 ) 4928 - 4937 .

Hariharan D, Constantinides VA, Froeling FEM, Tekkis PP, Kocher HM ( 2010 ) . The role of laparoscopy and laparoscopic ultrasound in the preoperative staging of pancreatico-biliary cancers--A meta-analysis . Eur J Surg Oncol vol. 36 , ( 10 ) 941 - 948 .

Froeling FEM, Marshall JF, Kocher HM ( 2010 ) . Pancreatic cancer organotypic cultures . J Biotechnol vol. 148 , ( 1 ) 16 - 23 .

Kocher HM, Alrawashdeh W ( 2010 ) . Pancreatic cancer . BMJ Clin Evid vol. 2010 ,

Lines KE, Audi N, Chelala C, Kocher H, Wijesuriya N, Hurst H, Crnogorac-Jurcevic T ( 2010 ) . Abstract 5288: S100PBP is ubiquitously expressed and modulates the function of S100 calcium-binding proteins in pancreatic cancer . Cancer Research . vol. 70 , 5288 - 5288 .

Ahmed I, Fotiadis NI, Dilks P, Kocher HM, Fotheringham T, Matson M ( 2010 ) . Multiple intrahepatic artery aneurysms in a patient with Behçet's disease: use of transcatheter embolization for rupture . Cardiovasc Intervent Radiol vol. 33 , ( 2 ) 398 - 401 .

Lin W-R, Lim S-N, McDonald SAC, Graham T, Wright VL, Peplow CL, Humphries A, Kocher HM et al. ( 2010 ) . The histogenesis of regenerative nodules in human liver cirrhosis . Hepatology vol. 51 , ( 3 ) 1017 - 1026 .

Smith M, Kocher HM, Hunt BJ ( 2010 ) . Aprotinin in severe acute pancreatitis . Int J Clin Pract vol. 64 , ( 1 ) 84 - 92 .

Partelli S, Mukherjee S, Mawire K, Hutchins RR, Abraham AT, Bhattacharya S, Kocher HM ( 2010 ) . Larger hepatic metastases are more frequent with N0 colorectal tumours and are associated with poor prognosis: implications for surveillance . Int J Surg vol. 8 , ( 6 ) 453 - 457 .

Kocher HM, Dervenis C, Olah A, Murray WR, Clements B, Imrie CW ( 2010 ) . Nutrition in Acute Pancreatitis . PANCREATIC DISEASE: PROTOCOLS AND CLINICAL RESEARCH . Editors: Johnson, CD, Imrie, CW , 31 - 40 .

Jawad N, Woolf AK, Chin-Aleong J-A, Greaves R, Kocher HM ( 2009 ) . Biliary Cystadenoma Causing Obstructive Jaundice: Case Report and Literature Review . Case Rep Gastroenterol vol. 3 , ( 3 ) 269 - 274 .

Froeling FEM, Mirza TA, Feakins RM, Seedhar A, Elia G, Hart IR, Kocher HM ( 2009 ) . Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells . Am J Pathol vol. 175 , ( 2 ) 636 - 648 .

Mukherjee S, Kocher HM, Hutchins RR, Bhattacharya S, Abraham AT ( 2009 ) . Impact of hospital volume on outcomes for pancreaticoduodenectomy: a single UK HPB centre experience . Eur J Surg Oncol vol. 35 , ( 7 ) 734 - 738 .

Partelli S, Beg S, Brown J, Vyas S, Kocher HM ( 2009 ) . Alteration in emergency theatre prioritisation does not alter outcome for acute appendicitis: comparative cohort study . World J Emerg Surg vol. 4 ,

Fellous TG, McDonald SAC, Burkert J, Humphries A, Islam S, De-Alwis NMW, Gutierrez-Gonzalez L, Tadrous PJ et al. ( 2009 ) . A methodological approach to tracing cell lineage in human epithelial tissues . Stem Cells vol. 27 , ( 6 ) 1410 - 1420 .

Fellous TG, Islam S, Tadrous PJ, Elia G, Kocher HM, Bhattacharya S, Mears L, Turnbull DM et al. ( 2009 ) . Locating the stem cell niche and tracing hepatocyte lineages in human liver . Hepatology vol. 49 , ( 5 ) 1655 - 1663 .

Iype S, Mirza TA, Propper DJ, Bhattacharya S, Feakins RM, Kocher HM ( 2009 ) . Neuroendocrine tumours of the gallbladder: three cases and a review of the literature . Postgrad Med J vol. 85 , ( 1002 ) 213 - 218 .

Li NF, Kocher HM, Salako MA, Obermueller E, Sandle J, Balkwill F ( 2009 ) . A novel function of colony-stimulating factor 1 receptor in hTERT immortalization of human epithelial cells . Oncogene vol. 28 , ( 5 ) 773 - 780 .

Kocher HM, Sandle J, Mirza TA, Li NF, Hart IR ( 2009 ) . Ezrin interacts with cortactin to form podosomal rosettes in pancreatic cancer cells . Gut vol. 58 , ( 2 ) 271 - 284 .

Iqbal N, Lovegrove RE, Tilney HS, Abraham AT, Bhattacharya S, Tekkis PP, Kocher HM ( 2009 ) . A comparison of pancreaticoduodenectomy with extended pancreaticoduodenectomy: a meta-analysis of 1909 patients . Eur J Surg Oncol vol. 35 , ( 1 ) 79 - 86 .

Kocher HM, Froeling FE ( 2008 ) . Chronic pancreatitis . BMJ Clin Evid vol. 2008 ,

Iqbal N, Lovegrove RE, Tilney HS, Abraham AT, Bhattacharya S, Tekkis PP, Kocher HM ( 2008 ) . A comparison of pancreaticoduodenectomy with pylorus preserving pancreaticoduodenectomy: A meta-analysis of 2822 patients . EJSO-EUR J SURG ONC vol. 34 , ( 11 ) 1237 - 1245 .

Mohamedali A, Lea NC, Feakins RM, Raj K, Mufti GJ, Kocher HM ( 2008 ) . AKT1 (E17K) mutation in pancreatic cancer . TECHNOL CANCER RES T vol. 7 , ( 5 ) 407 - 408 .

Gourgiotis S, Kocher HM, Solaini L, Yarollahi A, Tsiambas E, Salemis NS ( 2008 ) . Gallbladder cancer . Am J Surg vol. 196 , ( 2 ) 252 - 264 .

Weeks ME, Hariharan D, Petronijevic L, Radon TR, Whiteman HJ, Kocher HM, Timms JF, Lemoine NR et al. ( 2008 ) . Analysis of the urine proteome in patients with pancreatic ductal adenocarcinoma . PROTEOM CLIN APPL vol. 2 , ( 7-8 ) 1047 - 1057 .

POTTER VA, THATCHER N, WOLL PJ ( 2008 ) . Bronchus Vanessa A Potter, Nicholas Thatcher, Penella J Woll . Treatment of Cancer , Taylor & Francis

Mai-Phan TA, Patel B, Walsh M, Abraham AT, Kocher HM ( 2008 ) . Emergency room surgical workload in an inner city UK teaching hospital . World J Emerg Surg vol. 3 ,

Kocher H, Sandle J, Mirza TA, Li NF, Hart IR ( 2008 ) . A novel interaction of ezrin with cortactin in podosomal rosette assembly in pancreatic cancer cells . GASTROENTEROLOGY vol. 134 , ( 4 ) A288 - A288 .

Froeling FE, Mirza TA, Li NF, Hart IR, Kocher H ( 2008 ) . Organotypic culture modelling of pancreatic cancer . GASTROENTEROLOGY vol. 134 , ( 4 ) A586 - A586 .

Li NF, Froeling FE, Hart IR, Kocher H ( 2008 ) . RhoC enhances pancreatic carcinoma cell migration by mediating integrin signaling and podosome formation . GASTROENTEROLOGY vol. 134 , ( 4 ) A288 - A288 .

Kocher H, Sandle J, Mirza TA, Li NF, Hart IR ( 2008 ) . S1890 A Novel Interaction of Ezrin with Cortactin in Podosomal Rosette Assembly in Pancreatic Cancer Cells . Gastroenterology vol. 134 , ( 4 ) a - 288 .

Li NF, Froeling FE, Hart IR, Kocher H ( 2008 ) . S1891 RhoC Enhances Pancreatic Carcinoma Cell Migration By Mediating Integrin Signaling and Podosome Formation . Gastroenterology vol. 134 , ( 4 ) a - 288 .

Al-Ghnaniem R, Camprodon RAM, Kocher HM, Portmann B, Al-Nawab M, Shaikh H, Sohail M, Patel AG ( 2008 ) . Strategy to reduce the risk of positive pancreatic resection margin at pancreatico-duodenectomy . ANZ J Surg vol. 78 , ( 4 ) 237 - 239 .

Froeling FE, Mirza TA, Li NF, Hart IR, Kocher H ( 2008 ) . T1898 Organotypic Culture Modelling of Pancreatic Cancer . Gastroenterology vol. 134 , ( 4 ) a - 586 .

Kocher HM ( 2008 ) . Chronic pancreatitis . Am Fam Physician vol. 77 , ( 5 ) 661 - 662 .

Hariharan D, Saied A, Kocher HM ( 2008 ) . Analysis of mortality rates for gallbladder cancer across the world . HPB (Oxford) vol. 10 , ( 5 ) 327 - 331 .

Hariharan D, Saied A, Kocher HM ( 2008 ) . Analysis of mortality rates for pancreatic cancer across the world . HPB (Oxford) vol. 10 , ( 1 ) 58 - 62 .

Kocher HM, Abraham AT, Bhattacharya S ( 2008 ) . Biliary tract . Treatment of Cancer, Fifth Edition ,

O'Sullivan A, Kocher HM ( 2007 ) . Pancreatic cancer . BMJ Clin Evid vol. 2007 ,

Kocher HM, Sohail M, Benjamin IS, Patel AG ( 2007 ) . Technical limitations of lymph node mapping in pancreatic cancer . EJSO-EUR J SURG ONC vol. 33 , ( 7 ) 887 - 891 .

Kocher HM, Mears L, Lea NC, Raj K, Mufti GJ ( 2007 ) . JAK V617F missense mutation is absent in pancreatic cancer . Gut vol. 56 , ( 8 ) 1174 - 1175 .

Wong NSC, Kocher HP, Yap MGS ( 2007 ) . Meeting Report: Second Singapore Biologics Manufacturing Conference . Biotechnology Journal vol. 2 , ( 6 ) 657 - 658 .

Germanos S, Gourgiotis S, Kocher HM ( 2007 ) . Clinical update: early surgery for acute cholecystitis . Lancet vol. 369 , ( 9575 ) 1774 - 1776 .

Fellous TG, Britian M, Kocher H, Bhattacharya S, Tadrous PJ, Taylor GA, Greaves LC, Mcdonald SA et al. ( 2007 ) . Mitochondrial DNA mutations to investigate cell lineage relations in human liver . GASTROENTEROLOGY . vol. 132 , A830 - A830 .

Baril P, Gangeswaran R, Mahon PC, Caulee K, Kocher HM, Harada T, Zhu M, Kalthoff H et al. ( 2007 ) . Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway . Oncogene vol. 26 , ( 14 ) 2082 - 2094 .

Mukherjee S, Kocher HM, Hutchins RR, Bhattacharya S, Abraham AT ( 2007 ) . Palliative surgical bypass for pancreatic and peri-ampullary cancers . J Gastrointest Cancer vol. 38 , ( 2-4 ) 102 - 107 .

Kocher HM, Warwick J, Al-Ghnaniem R, Patel AG ( 2006 ) . Surgical dexterity after a 'night out on the town' . ANZ J SURG vol. 76 , ( 3 ) 110 - 112 .

Kocher HM, Senkus R, Al-Nawab M, Hendry BM ( 2005 ) . Subcellular distribution of Ras GTPase isoforms in normal human kidney . NEPHROL DIAL TRANSPL vol. 20 , ( 5 ) 886 - 891 .

Kocher HM, Tekkis PP, Gopal P, Patel AG, Cottam S, Benjamin IS ( 2005 ) . Risk-adjustment in hepatobiliary pancreatic surgery . World J Gastroenterol vol. 11 , ( 16 ) 2450 - 2455 .

Loong TPF, Kocher HM ( 2005 ) . Clinical presentation and operative repair of hernia of Morgagni . POSTGRAD MED J vol. 81 , ( 951 ) 41 - 44 .

Kocher HM, Senkus R, Moorhead J, Al-Nawab M, Patel AG, Benjamin IS, Hendry BM ( 2005 ) . Expression of Ras GTPase isoforms in normal and diseased pancreas . Pancreatology vol. 5 , ( 2-3 ) 205 - 214 .

Tekkis PP, Prytherch DR, Kocher HM, Senapati A, Poloniecki JD, Stamatakis JD, Windsor ACJ ( 2004 ) . Development of a dedicated risk-adjustment scoring system for colorectal surgery (colorectal POSSUM) . Br J Surg vol. 91 , ( 9 ) 1174 - 1182 .

Kocher HM, Moorhead J, Sharpe CC, Dockrell MEC, Al-Nawab M, Hendry BM ( 2003 ) . Expression of Ras GTPases in normal kidney and in glomerulonephritis . Nephrol Dial Transplant vol. 18 , ( 11 ) 2284 - 2292 .

Tekkis PP, Kessaris N, Kocher HM, Poloniecki JD, Lyttle J, Windsor ACJ ( 2003 ) . Author's reply: Evaluation of POSSUM and P-POSSUM scoring systems in patients undergoing colorectal surgery (Br J Surg 2003; 90 : 340-345) . BRIT J SURG vol. 90 , ( 8 ) 1021 - 1021 .

Khoury G ( 2003 ) . Evaluation of POSSUM and P‐POSSUM scoring systems in patients undergoing colorectal surgery (Br J Surg 2003; 90: 340‐345) . British Journal of Surgery vol. 90 , ( 8 ) 1021 - 1021 .

Kocher HM, Mohamed SA, Tekkis PP, Patel AG, Benjamin IS ( 2003 ) . Prediction of mortality and morbidity in hepatopancreaticobiliary surgery . BRITISH JOURNAL OF SURGERY . vol. 90 , 92 - 92 .

Clarke HC, Kocher HM, Khwaja A, Kloog Y, Cook HT, Hendry BM ( 2003 ) . Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis . J Am Soc Nephrol vol. 14 , ( 4 ) 848 - 854 .

Kocher HM, Tekkis PP ( 2003 ) . Surgical treatment of esophageal cancer . N Engl J Med vol. 348 , ( 12 ) 1177 - 1179 .

Tekkis PP, Kessaris N, Kocher HM, Poloniecki JD, Lyttle J, Windsor ACJ ( 2003 ) . Evaluation of POSSUM and P-POSSUM scoring systems in patients undergoing colorectal surgery . Br J Surg vol. 90 , ( 3 ) 340 - 345 .

Kocher HM, Tekkis PP, Payne JG ( 2003 ) . Abscess after appendicectomy in children: the role of conservative management . British Journal of Surgery vol. 86 , ( 1 ) 138 - 139 .

Kocher HM, Patel S, Linklater K, Ellul JPM ( 2002 ) . Increase in the incidence of oesophagogastric carcinoma in the South Thames region: an epidemiological study . British Journal of Surgery vol. 87 , ( 3 ) 362 - 363 .

Kocher HM, Steward M, Leather AJM, Cullen PT ( 2002 ) . Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17) - Reply . BRIT J SURG vol. 89 , ( 9 ) 1193 - 1194 .

Acheson AG, Griffin N, Scholefield JH ( 2002 ) . Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17) . Br J Surg vol. 89 , ( 9 )

Kocher HM, Al-Ghnaniem R, Patel AG ( 2002 ) . Surgical dexterity after a night out on the town . BRIT J SURG vol. 89 , 17 - 17 .

Kocher HMK, Codd J, Al-Nawab M, Benjamin IS, Patel AG, Hendry BM ( 2002 ) . Differential expression of RAS isoforms in normal and malignant human pancreas: An in vivo immunohistochemical analysis . GASTROENTEROLOGY vol. 122 , ( 4 ) A495 - A495 .

Al-Ghnaniem R, Kocher HMK, Portmann B, Al-Nawab M, Sheik H, Sohail M, Patel AG ( 2002 ) . Improving diagnostic accuracy of frozen section of the pancreatic resection margin at pancreatico-duodenectomy by concurrent examination of the suspected pancreatic lesion . GASTROENTEROLOGY vol. 122 , ( 4 ) A566 - A566 .

Kocher HMK, Sohail M, Benjamin IS, Patel AG ( 2002 ) . Lymph node mapping in pancreatic cancer: A feasibility study . GASTROENTEROLOGY vol. 122 , ( 4 ) A495 - A495 .

Kocher HM, Steward M, Leather AJM, Cullen PT ( 2002 ) . Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure . Br J Surg vol. 89 , ( 4 ) 413 - 417 .

Kocher HMK, Patel AG, Benjamin IS ( 2002 ) . World-wide trends in biliary tract cancer . GASTROENTEROLOGY vol. 122 , ( 4 ) A569 - A569 .

Tekkis PP, Kocher HM, Kessaris N, Poloniecki J, Prytherch D, Somers SS, Mcculloch P, Ellut JPM et al. ( 2002 ) . Risk adjustment in oesophagogastric surgery: a comparison of Bayesian analysis and logistic regression . BRIT J SURG vol. 89 , ( 3 ) 381 - 381 .

Al-Ghnaniem R, Kocher HM, Patel AG ( 2002 ) . Prediction of inflammation of the appendix at open and laparoscopic appendicectomy: findings and consequences . Eur J Surg vol. 168 , ( 1 ) 4 - 7 .

Kocher, Saunders ( 2001 ) . Complacency or ignorance about rectal bleeding? . Colorectal Disease vol. 1 , ( 6 ) 332 - 333 .

Kua KB, Kocher HM, Kelkar A, Patel AG ( 2001 ) . Effect of topical glyceryl trinitrate on anodermal blood flow in patients with chronic anal fissures . ANZ J Surg vol. 71 , ( 9 ) 548 - 550 .

Kocher HM, Linklater Y, Patel S, Ellul JPM ( 2001 ) . Epidemiological study of oesophageal and gastric cancer in south-east England . BRIT J SURG vol. 88 , ( 9 ) 1249 - 1257 .

Kocher HM, Al-Ghnaniem R, Patel AG ( 2001 ) . Major intra-abdominal pathology missed at laparoscopic cholecystectomy (Br J Surg 2000; 87: 1434-5) . Br J Surg vol. 88 , ( 6 )

Tekkis PP, Kocher HM, Kessaris N, Harrison TA, Slater N, Leather AJM, Windsor ACJ ( 2001 ) . How accurate is POSSUM and p-POSSUM in predicting mortality in emergency surgery and in old age? . BRIT J SURG vol. 88 , 42 - 43 .

Kelkar AP, Kocher HM, Makar AA, Patel AG ( 2001 ) . Extraction of retained gallstones from an abscess cavity: a percutaneous endoscopic technique . Surg Laparosc Endosc Percutan Tech vol. 11 , ( 2 ) 129 - 130 .

Kocher HM, Steward M, Leather AJ, Cullen PT ( 2001 ) . Topical Glyceryl Tri-Nitrate [GTN] (0.2%) vs topical diltiazem (2%) in the treatment of chronic fissure-in-ano: A prospective double-blind randomised trial . GASTROENTEROLOGY vol. 120 , ( 5 ) A130 - A130 .

KOCHER H, STEWARD M, LEATHER A, CULLEN P ( 2001 ) . Topical glyceryl Tri-Nitrate [GTN] (0.2%) vs topical diltiazem (2%) in the treatment of chronic fissure-in-ano: A prespective double-blind randomised trial . Gastroenterology vol. 120 , ( 5 ) a130 - a130 .

Kocher HM, Codd J, Al-Nawab M, Benjamin IS, Patel AG, Hendry BM ( 2001 ) . Differential expression of Ras isoforms in normal human pancreas: An in vivo immuno-histochemical analysis . GUT vol. 48 , A70 - A70 .

Wong T, Kocher H, Kane P, Karani J, Patel A, Devlin J ( 2001 ) . Evaluation of endoscopic ultrasound versus helical computed tomography in the assessment of pancreatic masses: Results from a UK centre . GUT vol. 48 , A65 - A65 .

Raj K, Shah S, Kocher HM ( 2000 ) . Consultant cover in intensive-care units . The Lancet vol. 356 , ( 9243 ) 1773 - 1774 .

Sagar P, Tekkis PP, Bentley AJE, South LM, Trotter GA, Ellul JPM, Kocher HM, Cullen PT ( 2000 ) . Invited editorial . Diseases of the Colon & Rectum vol. 43 , ( 11 ) 1532 - 1534 .

Tekkis PP, Kocher HM, Bentley AJE, Cullen PT, South LM, Trotter GA, Ellul JPM ( 2000 ) . Operative mortality rates among surgeons . Diseases of the Colon & Rectum . vol. 43 , 1528 - 1532 .

Kocher HM, Gupta S ( 2000 ) . Safety of pancreatic surgery in a small DGH . Annals of The Royal College of Surgeons of England vol. 82 , ( 1 )

Tekkis PP, Kocher HM, Payne JG ( 1999 ) . Parastomal hernia repair . Diseases of the Colon & Rectum vol. 42 , ( 11 ) 1505 - 1508 .

Tekkis PP, Bentley AJ, Kocher HM, South LM, Trotter GA ( 1999 ) . Risk scoring in surgical patients . British Journal of Surgery vol. 86 , ( 9 )

Tekkis PP, Kocher HM, Payne JG ( 1999 ) . The continuing challenge of parastomal hernia: failure of a novel polypropylene mesh repair . Annals of The Royal College of Surgeons of England vol. 81 , ( 2 ) 140 - 141 .

Tekkis PP, Bentley AJE, Kocher HM, South LM, Trotter GA ( 1999 ) . Erratum: Risk scoring in surgical patients (British Journal of Surgery (1999) 86 (1225)) . British Journal of Surgery vol. 86 , ( 11 )

Kocher H, Bapat R, Joshi A ( 1997 ) . Experimental model of obstructive jaundice in mongrel dog: study of subsequent pathological changes in liver . Indian Journal of Gastroenterology vol. 16 , ( 1 ) 6 - 9 .

Bapat RD, Supe AN, Patwardhan A, Kocher HM, Parab S, Sathe MJ ( 1996 ) . Biliary sepsis: an ascending infection . Indian Journal of Gastroenterology vol. 15 , ( 4 ) 126 - 128 .

Vijay KT, Kocher HH, Koti RS, Bapat RD ( 1996 ) . Agenesis of gall bladder--a diagnostic dilemma . Journal of Postgraduate Medicine vol. 42 , ( 3 ) 80 - 82 .

Kocher HM, Pandya SV, Rohandia OS, Pwadhwa R, Bhatia SJ, Joshi AS, Bapat RD ( 1995 ) . Adult Hirschsprung's disease . Indian Journal of Gastroenterology vol. 14 , ( 3 ) 108 - 109 .

Kocher HM, Vijaykumar T, Koti RS, Bapat RD ( 1995 ) . Lymphangioma of the chest wall . Journal of Postgraduate Medicine vol. 41 , ( 3 ) 89 - 90 .