Publications:  Prof Marta Korbonits

Marques P, Caimari F, Hernández-Ramírez LC, Collier A, Iacovazzo D, Ronaldson A, Magid K, Lim CT et al.(2020). Significant benefits of AIP testing and clinical screening in familial isolated and young-onset pituitary tumors. Journal of Clinical Endocrinology and Metabolism vol. 105, (6)

Pinto EM, Figueiredo BC, Chen W, Galvao HCR, Formiga MN, Fragoso MCBV, Ashton-Prolla P, Ribeiro EMSF et al.(2020). XAF1 as a modifier of p53 function and cancer susceptibility. Science Advances vol. 6, (26)

Iacovazzo D, Chiloiro S, Carlsen E, Bianchi A, Giampietro A, Tartaglione T, Bima C, Bracaccia ME et al.(2020). Tumour-infiltrating cytotoxic T lymphocytes in somatotroph pituitary neuroendocrine tumours. Endocrine vol. 67, (3) 651-658.

Pernicova I, Kelly S, Ajodha S, Sahdev A, Bestwick JP, Gabrovska P, Akanle O, Ajjan R et al.(2020). Metformin to reduce metabolic complications and inflammation in patients on systemic glucocorticoid therapy: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial. Lancet Diabetes and Endocrinology

Marques P, Stelmachowska-Banas M, Collier D, Wernig F, Korbonits M(2020). Pachydermoperiostosis mimicking the acral abnormalities of acromegaly. Endocrine vol. 67, (2) 499-500.

Dal J, Nielsen EH, Klose M, Feldt-Rasmussen U, Andersen M, Vang S, Korbonits M, Jørgensen JOL(2020). Phenotypic and genotypic features of a large kindred with a germline AIP variant. Clinical Endocrinology

Marques P, Barry S, Carlsen E, Collier D, Ronaldson A, Awad S, Dorward N, Grieve J et al.(2019). Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours. Acta neuropathologica communications vol. 7, (1)

Manou-Stathopoulou V, Korbonits M, Ackland GL(2019). Redefining the perioperative stress response: a narrative review. British Journal of Anaesthesia vol. 123, (5) 570-583.

Pofi R, Prete A, Thornton-Jones V, Bryce J, Ali SR, Faisal Ahmed S, Balsamo A, Baronio F et al.(2019). Plasma Renin Measurements are Unrelated to Mineralocorticoid Replacement Dose in Patients With Primary Adrenal Insufficiency. Journal of Clinical Endocrinology and Metabolism vol. 105, (1) 314-326.

Dutta A, Pal R, Jain N, Dutta P, Rai A, Bhansali A, Behera A, Saikia UN et al.(2019). Pediatric Parathyroid Carcinoma: A Case Report and Review of the Literature. Journal of the Endocrine Society vol. 3, (12) 2224-2235.

Hebenstreit D, Ahmed F, Springer A, Krall C, Krone N, Birkebaek N, Milenkovic T, Koehler B et al. (2019). Contemporary surgical approach in CAH 46XX-Results from the I-DSD/I-CAH Registries. HORMONE RESEARCH IN PAEDIATRICS. vol. 91, 96-97.

Ali S, Daniel E, Bryce J, Ikiroma A, Lewsey J, Ross R, Krone R, Acerini C et al. (2019). Development Of An International Benchmark For Sick Day Episodes As A Core Clinical Outcome In People With Congenital Adrenal Hyperplasia. HORMONE RESEARCH IN PAEDIATRICS. vol. 91, 209-210.

Bacila I-A, Blankenstein O, Neumann U, Claahsen-van der Grinten HL, Krone R, Acerini C, Bachega TSS, Miranda MC et al. (2019). Global Practice of Glucocorticoid and Mineralocorticoid Treatment in Children and Adults with Congenital Adrenal Hyperplasia - Insights from the I-CAH Registry. HORMONE RESEARCH IN PAEDIATRICS. vol. 91, 132-133.

Neumann U, van der Linde A, Krone R, Guven A, Guran T, Elsedfy H, Darendeliler F, Bachega T et al. (2019). Influence of salt supplementation on drug therapy in children with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency aged 0-3 years: Update on a retrospective multicentre analysis using the I-CAH registry. HORMONE RESEARCH IN PAEDIATRICS. vol. 91, 204-205.

Gan H-W, Morillon P, Albanese A, Aquilina K, Barkas K, Chandler C, Chang Y-C, Daousi C et al. (2019). National United Kingdom evidence- and consensus-based guidelines for the investigation, treatment and long-term follow-up of paediatric craniopharyngioma. HORMONE RESEARCH IN PAEDIATRICS. vol. 91, 99-100.

Dutta P, Reddy KS, Rai A, Madugundu AK, Solanki HS, Bhansali A, Radotra BD, Kumar N et al.(2019). Surgery, Octreotide, Temozolomide, Bevacizumab, Radiotherapy, and Pegvisomant Treatment of an AIP Mutation-Positive Child. Journal of Clinical Endocrinology and Metabolism vol. 104, (8) 3539-3544.

Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C et al.(2019). Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors. Oncogene vol. 38, (27) 5381-5395.

Ribeiro-Oliveira A, Korbonits M, V Freire C(2019). Assessment of Cardiavascular Changes following Trans-sphenoidal Surgery in Acromegalic Patients. Neurology India vol. 67, (4) 1170-1171.

Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X et al.(2019). Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation. Cell Reports vol. 27, (5) 1461-1471.e4.

Drummond J, Roncaroli F, Grossman AB, Korbonits M(2019). Clinical and Pathological Aspects of Silent Pituitary Adenomas. Journal of Clinical Endocrinology and Metabolism vol. 104, (7) 2473-2489.

Castinetti F, Waguespack SG, Machens A, Uchino S, Hasse-Lazar K, Sanso G, Else T, Dvorakova S et al.(2019). Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study. The Lancet Diabetes and Endocrinology vol. 7, (3) 213-220.

Pepe S, Korbonits M, Iacovazzo D(2019). Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects. Journal of Endocrinology vol. 240, (2) R21-R45.

Jawiarczyk-Przyby¿owska A, Wojtczak B, Whitworth J, Sutkowski K, Bidlingmaier M, Korbonits M, Bolanowski M(2019). Acromegaly associated with GIST, non-small cell lung carcinoma, clear cell renal carcinoma, multiple myeloma, medulla oblongata tumour, adrenal adenoma, and follicular thyroid nodules. Endokrynologia Polska vol. 70, (2) 213-218.

Stojanovic M, Wu Z, Stiles CE, Miljic D, Soldatovic I, Pekic S, Doknic M, Petakov M et al.(2019). Circulating aryl hydrocarbon receptor-interacting protein (Aip) is independent of gh secretion. Endocrine Connections vol. 8, (4) 326-337.

Loughrey PB, Korbonits M(2019). Genetics of Pituitary Tumours. Genetics of Endocrine Diseases and Syndromes vol. 111, 171-211.

Bizzi MF, Bolger GB, Korbonits M, Ribeiro-Oliveira A(2019). Phosphodiesterases and cAMP pathway in pituitary diseases. Frontiers in Endocrinology vol. 10, (MAR)

Marques P, Barry S, Carlsen E, Collier D, Ronaldson A, Awad S, Dorward N, Grieve J et al.(2019). Pituitary tumour fibroblast-derived cytokines influence tumour aggressiveness. Endocrine-Related Cancer vol. 26, (12) 853-865.

Marques P, Korbonits M(2019). Pseudoacromegaly. Frontiers in Neuroendocrinology vol. 52, 113-143.

Ali SR, Bryce J, Cools M, Korbonits M, Beun JG, Taruscio D, Danne T, Dattani M et al.(2019). The current landscape of European registries for rare endocrine conditions. European journal of endocrinology vol. 180, (1) 89-98.

Marques P, Collier D, Barkan A, Korbonits M(2018). Coexisting pituitary and non-pituitary gigantism in the same family. Clinical Endocrinology vol. 89, (6) 887-888.

Scudder CJ, Mirczuk SM, Richardson KM, Crossley VJ, Regan JTC, Gostelow R, Forcada Y, Hazuchova K et al.(2018). Pituitary pathology and gene expression in acromegalic cats. Journal of the Endocrine Society vol. 3, (1) 181-200.

Günther T, Tulipano G, Dournaud P, Bousquet C, Csaba Z, Kreienkamp HJ, Lupp A, Korbonits M et al.(2018). International union of basic and clinical pharmacology. CV. somatostatin receptors: Structure, function, ligands, and new nomenclature. Pharmacological Reviews vol. 70, (4) 763-835.

Aflorei ED, Klapholz B, Chen C, Radian S, Dragu AN, Moderau N, Prodromou C, Ribeiro PS et al.(2018). In vivo bioassay to test the pathogenicity of missense human AIP variants. Journal of Medical Genetics vol. 55, (8) 522-529.

Caimari F, Kumar AV, Kurzawinski T, Butler G, Sabbaghian N, Foulkes WD, KORBONITS M(2018). A novel DICER1 mutation in familial multinodular goitre. Clinical Endocrinology vol. 89, (1) 110-112.

Németh K, Szücs N, Czirják S, Reiniger L, Szabó B, Barna G, Karászi K, Igaz P et al.(2018). Survivin as a potential therapeutic target of acetylsalicylic acid in pituitary adenomas. Oncotarget vol. 9, (49) 29180-29192.

Blair J, Korbonits M, Ronaldson A, Dang M, Spoudeas H (2018). A NATIONAL UK GUIDELINE FOR MANAGING PITUITARY ADENOMAS IN CHILDREN AND YOUNG PEOPLE UNDER 19 YEARS DEVELOPED ACCORDING TO THE AGREE II FRAMEWORK. NEURO-ONCOLOGY. vol. 20, 44-45.

Gan H-W, Aquilina K, Morillon P, Albanese A, Barkas K, Chandler C, Chang Y-C, Daousi C et al. (2018). NATIONAL UK GUIDELINES FOR THE INVESTIGATION, TREATMENT AND LONG-TERM FOLLOW-UP OF PAEDIATRIC CRANIOPHARYNGIOMA. NEURO-ONCOLOGY. vol. 20, 38-38.

Bizzi MF, Pinheiro SVB, Bolger GB, Schweizer JRDOL, Giannetti AV, Dang MN, Ribeiro-Oliveira A, Korbonits M(2018). Reduced protein expression of the phosphodiesterases PDE4A4 and PDE4A8 in AIP mutation positive somatotroph adenomas. Molecular and Cellular Endocrinology

Prete FP, Abdel-Aziz T, Morkane C, Brain C, Kurzawinski TR, Hindmarsh P, Dattani M, Spoudeas H et al.(2018). Prophylactic thyroidectomy in children with multiple endocrine neoplasia type 2. British Journal of Surgery vol. 105, (10) 1319-1327.

Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N et al.(2018). Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target. Acta Neuropathologica vol. 135, (5) 757-777.

Lim CT, Korbonits M(2018). UPDATE ON THE CLINICOPATHOLOGY OF PITUITARY ADENOMAS. Endocr Pract vol. 24, (5) 473-488.

Marques P, Barry S, Ronaldson A, Ogilvie A, Storr HL, Goadsby PJ, Powell M, Dang MN et al.(2018). Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members' View in an AIP Mutation-Positive Family. Int J Endocrinol vol. 2018, 8581626-8581626.

Korbonits M, Caimari F, Hernández-Ramírez LC, Dang MN, Gabrovska P, Iacovazzo D, Stals K, Ellard S(2018). Risk category system to identify pituitary adenoma patients with AIP mutations. Journal of Medical Genetics vol. 55, (4) 254-260.

Stiles CE, Thuraisingham R, Bockenhauer D, Platts L, Kumar AV, Korbonits M(2018). De novo HNF1 homeobox B mutation as a cause for chronic, treatment-resistant hypomagnesaemia. Endocrinol Diabetes Metab Case Rep vol. 2018,

Iacovazzo D, Flanagan SE, Walker E, Quezado R, de Sousa Barros FA, Caswell R, Johnson MB, Wakeling M et al.(2018). MAFA missense mutation causes familial insulinomatosis and diabetes mellitus. Proc Natl Acad Sci U S A vol. 115, (5) 1027-1032.

Marques P, Spencer R, Morrison PJ, Carr IM, Dang MN, Bonthron DT, Hunter S, Korbonits M(2018). Cantú syndrome with coexisting familial pituitary adenoma. Endocrine1-8.

Blair J, Korbonits M, Ronaldson A, Dang MN, Spoudeas H (2018). A National UK Guideline for Managing Pituitary Adenomas in Children and Young People Under 19 Years Developed According to The AGREE II Framework. HORMONE RESEARCH IN PAEDIATRICS. vol. 90, 499-499.

Ali SR, Bryce J, Cools M, Korbonits M, Beun JG, Taruscio D, Beuschlein F, Danne T et al. (2018). Awareness & Participation in Rare Disease Registries Within the European Reference Network on Rare Endocrine Conditions (Endo-ERN). HORMONE RESEARCH IN PAEDIATRICS. vol. 90, 70-70.

Ilie I, Korbonits M(2018). Clinical features of acromegaly. Encyclopedia of Endocrine Diseases,

Ilie I, Korbonits M(2018). Diagnosis of acromegaly. Encyclopedia of Endocrine Diseases,

Costa MM, Korbonits M(2018). Genetic causes of familial pituitary tumors. Encyclopedia of Endocrine Diseases,

Garcia JM, Biller BMK, Korbonits M, Popovic V, Luger A, Strasburger CJ, Chanson P, Medic-Stojanoska M et al.(2018). Macimorelin as a diagnostic test for adult GH deficiency. Journal of Clinical Endocrinology and Metabolism vol. 103, (8) 3083-3093.

Ferraù F, Korbonits M(2018). Metabolic syndrome in cushing's syndrome patients. Frontiers of Hormone Research vol. 49, 85-103.

Hernández-Ramírez LC, Morgan RML, Barry S, D'Acquisto F, Prodromou C, Korbonits M(2018). Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland. Oncotarget vol. 9, (10) 9177-9198.

Yelamanchi SD, Tyagi A, Mohanty V, Dutta P, Korbonits M, Chavan S, Advani J, Madugundu AK et al.(2018). Proteomic Analysis of the Human Anterior Pituitary Gland. OMICS A Journal of Integrative Biology vol. 22, (12) 759-769.

Pérez-Rivas LG, Theodoropoulou M, Puar TH, Fazel J, Stieg MR, Ferraù F, Assié G, Gadelha MR et al.(2018). Somatic USP8 mutations are frequent events in corticotroph tumor progression causing Nelson's tumor. European Journal of Endocrinology vol. 178, (1) 57-63.

Araujo PB, Kasuki L, de Azeredo Lima CH, Ogino L, Camacho AHS, Chimelli L, Korbonits M, Gadelha MR(2017). AIP mutations in brazilian patients with sporadic pituitary adenomas: A single-center evaluation. Endocrine Connections vol. 6, (8) 914-925.

Ribeiro-Oliveira A, Korbonits M, Freire C(2017). Echocardiographic improvements following transsphenoidal surgery for acromegaly. Neurology India vol. 65, (6) 1225-1226.

Koehler VF, Jungheim K, Groß U, Iacovazzo D, Mann A, Korbonits M(2017). Novel Germline p.Gly42Val MEN1 Mutation in a Family with Multiple Endocrine Neoplasia Type 1 - Excellent Response of Prolactinoma to Cabergoline. Ann Clin Lab Sci vol. 47, (5) 606-610.

Ibáñez-Costa A, Korbonits M(2017). AIP and the somatostatin system in pituitary tumours. Journal of Endocrinology vol. 235, (3) R101-R116.

Ibáñez-Costa A, Korbonits M(2017). AIP and the somatostatin system in pituitary tumours. J Endocrinol vol. 235, (3) R101-R116.

Kiefer FW, Winhofer Y, Iacovazzo D, Korbonits M, Wolfsberger S, Knosp E, Trautinger F, Höftberger R et al.(2017). PRKAR1A mutation causing pituitary-dependent Cushing disease in a patient with Carney complex. Eur J Endocrinol vol. 177, (2) K7-K12.

Dahlqvist P, Spencer R, Marques P, Dang MN, Glad CAM, Johannsson G, Korbonits M(2017). Pseudoacromegaly: A differential diagnostic problem for acromegaly with a genetic solution. Journal of the Endocrine Society vol. 1, (8) 1104-1109.

Butz H, Németh K, Czenke D, Likó I, Czirják S, Zivkovic V, Baghy K, Korbonits M et al.(2017). Systematic Investigation of Expression of G2/M Transition Genes Reveals CDC25 Alteration in Nonfunctioning Pituitary Adenomas. Pathology and Oncology Research vol. 23, (3) 633-641.

Salvatori R, Radian S, Diekmann Y, Iacovazzo D, David A, Gabrovska P, Grassi G, Bussell A-M et al.(2017). In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism. Eur J Endocrinol vol. 177, (3) 257-266.

Marques P, Korbonits M(2017). Genetic Aspects of Pituitary Adenomas. Endocrinol Metab Clin North Am vol. 46, (2) 335-374.

Shaid M, Korbonits M(2017). Genetics of pituitary adenomas. Neurology India vol. 65, (3) 577-587.

Doleschall M, Luczay A, Koncz K, Hadzsiev K, Erhardt É, Szilágyi Á, Doleschall Z, Németh K et al.(2017). A unique haplotype of RCCX copy number variation: from the clinics of congenital adrenal hyperplasia to evolutionary genetics. Eur J Hum Genet vol. 25, (6) 702-710.

Asa SL, Casar-Borota O, Chanson P, Delgrange E, Earls P, Ezzat S, Grossman A, Ikeda H et al.(2017). From pituitary adenoma to pituitary neuroendocrine tumor (pitnet): An international pituitary pathology club proposal. Endocrine-Related Cancer vol. 24, (4) C5-C8.

Bulwer C, Conn R, Shankar A, Ferrau F, Kapur S, Ederies A, Korbonits M, Spoudeas HA(2017). Cabergoline-related impulse control disorder in an adolescent with a giant prolactinoma. Clinical Endocrinology

Iacovazzo D, Hernández-Ramírez LC, Korbonits M(2017). Sporadic pituitary adenomas: the role of germline mutations and recommendations for genetic screening. Expert Review of Endocrinology and Metabolism vol. 12, (2) 143-153.

Tufton N, Roncaroli F, Hadjidemetriou I, Dang MN, Dénes J, Guasti L, Thom M, Powell M et al.(2017). Pituitary Carcinoma in a Patient with an SDHB Mutation. Endocr Pathol vol. 28, (4) 320-325.

Thomas JDJ, Dattani A, Zemrak F, Burchell T, Akker SA, Kaplan FJL, Khoo B, Aylwin S et al.(2017). Renin-Angiotensin System Blockade Improves Cardiac Indices in Acromegaly Patients. Experimental and Clinical Endocrinology and Diabetes

Mitra MT, Jönsson P, Åkerblad AC, Clayton P, Ko¿towska-Häggström M, Korbonits M, Toogood A, Gleeson H(2017). Social, educational and vocational outcomes in patients with childhood-onset and young-adult-onset growth hormone deficiency. Clinical Endocrinology

Roncaroli F, Iacovazzo D, Rodd C, Gurlek A, Dutta P, Ellard S, Sampson J, Trouillas J et al. (2017). Distinct pathological features of pituitary adenomas in patients with X-linked acrogigantism (XLAG). NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. Conference: 118th Meeting of the British-Neuropathological-Society vol. 43, 20-20.

Tufton N, Shapiro L, Srirangalingam U, Richards P, Sahdev A, Kumar AV, McAndrew L, Martin L et al.(2017). Outcomes of annual surveillance imaging in an adult and paediatric cohort of succinate dehydrogenase B mutation carriers. Clinical Endocrinology vol. 86, (2) 286-296.

Roncaroli F, Tufton N, Hadjidemetriou I, Dang MD, Guasti L, Powell M, Baldeweg E, Fersht N et al. (2017). Pituitary carcinoma in a patient with germline Succinate Dehydrogenase B mutation. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. Conference: 118th Meeting of the British-Neuropathological-Society vol. 43, 46-46.

Srirangalingam U, Banerjee A, Patki P, Peters J, George E, Chew SL, Kumar VKA, Korbonits M et al.(2017). Succinate Dehydrogenase B (SDHB)-Associated Bladder Paragangliomas. Clinical Genitourinary Cancer vol. 15, (1) e131-e136.

Gadelha MR, Kasuki L, Korbonits M(2017). The genetic background of acromegaly. Pituitary vol. 20, (1) 10-21.

Karimova MM, Halimova ZY, Urmanova YM, Korbonits M, Cranston T, Grossman AB(2017). Pachydermoperiostosis masquerading as acromegaly. Journal of the Endocrine Society vol. 1, (2) 109-112.

Seelig E, Meyer S, Timper K, Nigro N, Bally M, Pernicova I, Schuetz P, Müller B et al.(2017). Metformin prevents metabolic side effects during systemic glucocorticoid treatment. Eur J Endocrinol vol. 176, (3) 349-358.

Stelmachowska-Banás M, Zgliczy¿ski W, Tutka P, Aidan Carney J, Korbonits M(2017). Fatal carney complex in siblings due to de novo large gene deletion. Journal of Clinical Endocrinology and Metabolism vol. 102, (11) 3924-3927.

Radian S, Diekmann Y, Gabrovska P, Holland B, Bradley L, Wallace H, Stals K, Bussell AM et al.(2017). Increased Population Risk of AIP-Related Acromegaly and Gigantism in Ireland. Human Mutation vol. 38, (1) 78-85.

Marques P, Pereira C, Korbonits M(2017). Langerhans cell histiocytosis: Pathophysiology, diagnosis, and management. The Art of Neuroendocrinology: A Case-Based Approach to Medical Decision-Making,

Gan H-W, Albanese A, Morillon P, Aquilina K, Barkas K, Chandler C, Chang Y-C, Daousi C et al. (2017). NATIONAL UK GUIDELINES FOR THE INVESTIGATION, TREATMENT AND LONG-TERM FOLLOW-UP OF PAEDIATRIC CRANIOPHARYNGIOMA. HORMONE RESEARCH IN PAEDIATRICS. vol. 88, 510-511.

Caimari F, Korbonits M(2016). Novel genetic causes of pituitary adenomas. Clinical Cancer Research vol. 22, (20) 5030-5042.

Iacovazzo D, Korbonits M(2016). Gigantism: X-linked acrogigantism and GPR101 mutations. Growth Horm IGF Res vol. 30-31, 64-69.

Thomas JDJ, Dattani A, Zemrak F, Burchell T, Akker SA, Gurnell M, Grossman AB, Davies LC et al.(2016). Characterisation of myocardial structure and function in adult-onset growth hormone deficiency using cardiac magnetic resonance. Endocrine

Ramírez-Rentería C, Hernández-Ramírez LC, Portocarrero-Ortiz L, Vargas G, Melgar V, Espinosa E, Espinosa-de-los-Monteros AL, Sosa E et al.(2016). AIP mutations in young patients with acromegaly and the Tampico Giant: the Mexican experience. Endocrine vol. 53, (2) 402-411.

Yelamanchi SD, Solanki HS, Radhakrishnan A, Balakrishnan L, Advani J, Raja R, Sahasrabuddhe NA, Mathur PP et al.(2016). Signaling network map of the aryl hydrocarbon receptor. Journal of Cell Communication and Signaling

Bolger GB, Bizzi MF, Pinheiro SV, Trivellin G, Smoot L, Accavitti M-A, Korbonits M, Ribeiro-Oliveira A(2016). cAMP-specific PDE4 phosphodiesterases and AIP in the pathogenesis of pituitary tumors. Endocrine-Related Cancer vol. 23, (5) 419-431.

Hernández-Ramírez LC, Martucci F, Morgan RML, Trivellin G, Tilley D, Ramos-Guajardo N, Iacovazzo D, D'Acquisto F et al.(2016). Rapid Proteasomal Degradation of Mutant Proteins Is the Primary Mechanism Leading to Tumorigenesis in Patients With Missense AIP Mutations. Journal of Clinical Endocrinology and Metabolism vol. 101, (8) 3144-3154.

Iacovazzo D, Caswell R, Bunce B, Jose S, Yuan B, Hernández-Ramírez LC, Kapur S, Caimari F et al.(2016). Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study. Acta Neuropathologica Communications vol. 4, (1)

Ferreira VM, Marcelino M, Piechnik SK, Marini C, Karamitsos TD, Ntusi NAB, Francis JM, Robson MD et al.(2016). Pheochromocytoma is characterized by catecholamine-mediated myocarditis, focal and diffuse myocardial fibrosis, and myocardial dysfunction. Journal of the American College of Cardiology vol. 67, (20) 2364-2374.

Vujovic S, Vujosevic S, Kavaric S, Sopta J, Ivovic M, Saveanu A, Brue T, Korbonits M et al.(2016). Cancerous leptomeningitis and familial congenital hypopituitarism. Endocrine vol. 52, (2) 231-235.

Rodd C, Millette M, Iacovazzo D, Stiles CE, Barry S, Evanson J, Albrecht S, Caswell R et al.(2016). Somatic GPR101 Duplication Causing X-Linked Acrogigantism (XLAG)—Diagnosis and Management. The Journal of Clinical Endocrinology & Metabolism vol. 101, (5) 1927-1930.

Koehler VF, Jungheim K, Gross U, Iacovazzo D, Korbonits M, Mann WA (2016). Novel germline p.Gly42Val MEN1 mutation in a family with multiple endocrine neoplasia type 1.

Dutta P, Korbonits M, Sachdeva N, Gupta P, Srinivasan A, Devgun JS, Bajaj A, Mukherjee KK(2016). Can immediate postoperative random growth hormone levels predict long-term cure in patients with acromegaly?. Neurology India vol. 64, (2) 252-258.

Syro LV, Rotondo F, Kovacs K, Korbonits M(2016). Clinicopathologic features of familial pituitary adenomas. Diagnostic Histopathology vol. 22, (3) 85-91.

Strasburger CJ, Karavitaki N, Stormann S, Trainer PJ, Kreitschmann-Andermahr I, Droste M, Korbonits M, Feldmann B et al.(2016). Patient-reported outcomes of parenteral somatostatin analogue injections in 195 patients with acromegaly. European Journal of Endocrinology vol. 174, (3) 355-362.

Iacovazzo D, Carlsen E, Lugli F, Chiloiro S, Piacentini S, Bianchi A, Giampietro A, Mormando M et al.(2016). Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: An immunohistochemical study. European Journal of Endocrinology vol. 174, (2) 241-250.

Scagliotti V, Avagliano L, Gualtieri A, Graziola F, Doi P, Chalker J, Righini A, Korbonits M et al.(2016). Histopathology and molecular characterisation of intrauterine-diagnosed congenital craniopharyngioma. Pituitary vol. 19, (1) 50-56.

Hernandez-Ramirez LC, Morgan RML, Chrisostomos Prodromou C, Korbonits M (2016). A Proteomic Approach to Unveil the Pituitary-Specific Tumour Suppressor Mechanisms of AIP. Conference: Endocr. RevSUN-505.

Portocarrero-Ortiz L, Martinez-Gigena MP, Alcocer-Barradas V, Korbonits M, Iacovazzo D, Dang MN, Ramirez C, Mercado M (2016). Clinical Case : Gigantism Due to AIP Mutation in a 9 Years-Old Identical Twin. Conference: Endocr. RevSUN-566.

Caimari F, Dang MN, Hernandez-Ramirez LC, Iacovazzo D, Korbonits M, Consortium TIFIPA (2016). Clinical Characteristics Predicting AIP Mutation Status in Pituitary Adenoma Patients. Conference: Endocr. RevOR42-OR45.

Korbonits M, Dutta P, Reddy KS, Bhansali A, Gupta P, Rai A, Radotra BD, Mukherjee KK (2016). Exome Sequencing Reveals Double Hit By AIP Gene Mutation and Copy Loss of Chromosome 11 but Negative X-LAG in a Pituitary Adenoma of a 4 Yrs Child with Gigantism Treated with Multimodal Therapy. Conference: Endocr. RevLBSat-27.

Scudder CJ, Mirczuk SM, Richardson KM, Gostelow R, Forcada Y, McGonnell IM, Church D, Lamb C et al. (2016). Feline Hypersomatotropism As a Spontaneous Animal Model of Acromegaly: Molecular Analyses of Somatostatin and Dopamine Receptor Expression in GH-Secreting Adenomas in the Cat (Felis catus). Conference: Endocr. RevLBSat-29.

Iacovazzo D, Kapur S, Bunce B, Ferrau F, Gabrovska P, Caswell R, Larkin SJ, Ansorge O et al. (2016). GPR101 Variants in Acromegaly: Results from a Large Series of Patients. Conference: Endocr. RevSUN-534.

Anandhakrishnan A, Korbonits M(2016). Glucagon-like peptide 1 in the pathophysiology and pharmacotherapy of clinical obesity. World Journal of Diabetes vol. 7, (20) 572-598.

Dworakowska D, Paulina Szyszka P, Diaz-Cano SJ, Weitsman G, Korbonits M, Grossman AB, Bornstein SR, Ng T (2016). Metformin Alters an Anti-Proliferative Effect of Mitotane in a Human Adrenocortical Cancer (H295R) Cell Line: Preliminary Results. Conference: Endocr. RevSAT-411.

Korbonits M, Millette M, Iacovazzo D, Stiles CE, Barry S, Evanson J, Albrecht S, Caswell R et al. (2016). Somatic Xq26.3 Microduplication Causing X-Linked Acrogigantism (X-LAG). Conference: Endocr. RevLBSat-28.

Iacovazzo D, Jose S, Bunce B, Caswell R, Kapur S, Hernandez-Ramirez LC, Caimari F, Dang MN et al. (2016). X-Linked Acrogigantism (X-LAG): Novel Histopathological and Clinical Characterisation. Conference: Endocr. RevOR42-OR44.

Nölting S, Maurer J, Spöttl G, Prada ETA, Reuther C, Young K, Korbonits M, Göke B et al.(2015). Additive Anti-Tumor Effects of Lovastatin and Everolimus in Vitro through Simultaneous Inhibition of Signaling Pathways. PLoS ONE vol. 10, (12)

Renukanthan A, Quinton R, Turner B, MacCallum P, Seal L, Davies A, Green R, Evanson J et al.(2015). Kallmann syndrome patient with gender dysphoria, multiple sclerosis, and thrombophilia. Endocrine vol. 50, (2) 496-503.

Agustsson TT, Baldvinsdottir T, Jonasson JG, Olafsdottir E, Steinthorsdottir V, Sigurdsson G, Thorsson AV, Carroll PV et al.(2015). The epidemiology of pituitary adenomas in Iceland, 1955-2012: A nationwide population-based study. European Journal of Endocrinology vol. 173, (5) 655-664.

Ribeiro-Oliveira A, Marques MB, Vilas-Boas WW, Guimarães J, Coimbra CC, Anjos AP, Fóscolo RB, Santos R et al.(2015). The effects of chronic candesartan treatment on cardiac and hepatic adenosine monophosphate-activated protein kinase in rats submitted to surgical stress. JRAAS - Journal of the Renin-Angiotensin-Aldosterone System vol. 16, (3) 481-487.

Perez-Rivas LG, Theodoropoulou M, Ferraù F, Nusser C, Kawaguchi K, Stratakis CA, Rueda Faucz F, Wildemberg LE et al.(2015). The gene of the ubiquitin-specific protease 8 is frequently mutated in adenomas causing cushing's disease. Journal of Clinical Endocrinology and Metabolism vol. 100, (7) E997-E1004.

Niessen SJM, Forcada Y, Mantis P, Lamb CR, Harrington N, Fowkes R, Korbonits M, Smith K et al.(2015). Studying cat (Felis catus) diabetes: Beware of the acromegalic imposter. PLoS ONE vol. 10, (5)

Melmed S, Popovic V, Bidlingmaier M, Mercado M, Van Der Lely AJ, Biermasz N, Bolanowski M, Coculescu M et al.(2015). Safety and efficacy of oral octreotide in acromegaly: Results of a multicenter phase III trial. Journal of Clinical Endocrinology and Metabolism vol. 100, (4) 1699-1708.

Dénes J, Kasuki L, Trivellin G, Colli LM, Takiya CM, Stiles CE, Barry S, De Castro M et al.(2015). Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas. PLoS ONE vol. 10, (2)

Ferreira VM, Marcelino M, Piechnik SK, Marini C, Karamitsos TD, Francis JM, Arnold JR, Mihai R et al.(2015). Multi-parametric cardiovascular magnetic resonance imaging detects subclinical myocardial involvement in patients diagnosed with phaeochromocytoma. Journal of Cardiovascular Magnetic Resonance1-2.

Diaz-Cano S, Szyszka P, Weitsman G, Dudka D, King P, Korbonits M, Grossman A, Schulte K-M et al. (2015). Effect of Erlotinib on Proliferation and Steriodogenesis in Primary Cultures of Adrenocortical Carcinoma. LABORATORY INVESTIGATION. vol. 95, 133A-133A.

Glynn NGL, Korbonits M(2015). A 25-year-old woman with headache and joint pain. Endocrinology and Diabetes: Case Studies, Questions and Commentaries,

Iacovazzo D, Piacentini S, Lugli F, Bianchi A, Gabrovska P, Persiani R, Rindi G, Ellard S et al. (2015). A Novel MEN1 Gene Variant in a Sporadic Case of Multiple Endocrine Neoplasia Type 1. NEUROENDOCRINOLOGY. vol. 102, 150-150.

Dutta P, Hajela A, Pathak A, Bhansali A, Radotra BD, Vashishta RK, Korbonits M, Khandelwal N et al.(2015). Clinical profile and outcome of patients with acromegaly according to the 2014 consensus guidelines: Impact of a multi-disciplinary team. Neurology India vol. 63, (3) 360-368.

Soh LM, Druce M, Grossman AB, Differ AM, Rajput L, Bitner-Glindzicz M, Korbonits M(2015). Evaluation of genotype-phenotype relationships in patients referred for endocrine assessment in suspected Pendred syndrome. European Journal of Endocrinology vol. 172, (2) 217-226.

Lim SV, Marenzana M, Hopkinson M, List EO, Kopchick JJ, Pereira M, Javaheri B, Roux JP et al.(2015). Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength. Endocrinology vol. 156, (4) 1362-1371.

Gardner CJ, Mattsson AF, Daousi C, Korbonits M, Koltowska-Haggstrom M, Cuthbertson DJ(2015). GH deficiency after traumatic brain injury: Improvement in quality of life with GH therapy: Analysis of the KIMS database. European Journal of Endocrinology vol. 172, (4) 371-381.

Müller TD, Nogueiras R, Andermann ML, Andrews ZB, Anker SD, Argente J, Batterham RL, Benoit SC et al.(2015). Ghrelin. Molecular Metabolism vol. 4, (6) 437-460.

Dénes J, Swords F, Rattenberry E, Stals K, Owens M, Cranston T, Xekouki P, Moran L et al.(2015). Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: Results from a large patient cohort. Journal of Clinical Endocrinology and Metabolism vol. 100, (3) E531-E541.

Hernández-Ramírez LC, Gabrovska P, Dénes J, Stals K, Trivellin G, Tilley D, Ferraù F, Evanson J et al.(2015). Landscape of familial isolated and young-onset pituitary adenomas: Prospective diagnosis in AIP mutation carriers. Journal of Clinical Endocrinology and Metabolism vol. 100, (9) E1242-E1254.

Ferraù F, Korbonits M (2015). Metabolic comorbidities in Cushing's syndrome. European Journal of Endocrinology. vol. 173, M133-M157.

Kumar S, Yadav RN, Gupta P, Gaspar BL, Kakkar N, Verma A, Parthan G, Bhansali A et al.(2015). Prostatic hyperplasia in acromegaly, a myth or reality: A case-control study. European Journal of Endocrinology vol. 173, (2)

O'Toole SM, Dénes J, Robledo M, Stratakis CA, Korbonits M(2015). The association of pituitary adenomas and phaeochromocytomas or paragangliomas. Endocrine-Related Cancer vol. 22, (4) T105-T122.

Solomou S, Korbonits M(2014). The role of ghrelin in weight-regulation disorders: Implications in clinical practice. Hormones vol. 13, (4) 458-475.

Doleschall M, Szabó JA, Pázmándi J, Szilágyi Á, Koncz K, Farkas H, Tóth M, Igaz P et al.(2014). Common genetic variants of the human steroid 21-hydroxylase gene (CYP21A2) are related to differences in circulating hormone levels. PLoS ONE vol. 9, (9)

Iacovazzo D, Sampson JR, Morrison PJ, Foulkes W, Alevizaki M, Lugli F, Gabrovska P, Lucci-Cordisco E et al.(2014). Five families with RET-mutation negative familial medullary thyroid carcinoma: what lies beyond RET?. WIENER KLINISCHE WOCHENSCHRIFT vol. 126, S141-S142.

Ferreira V, Marcelino M, Piechnik S, Marini C, Karamitsos T, Francis J, Arnold JR, Mihai R et al. (2014). CARDIAC ABNORMALITIES ARE COMMON IN PATIENTS DIAGNOSED WITH PHAEOCHROMOCYTOMA AS DETECTED BY CARDIOVASCULAR MAGNETIC RESONANCE IMAGING. HEART. vol. 100, A70-A70.

Salvatori R, Gabrovska P, Weber A, Quinton R, Crowne EC, Corazzini V, Radian S, Sinha K et al. (2014). Founder Effect in Recurring AIP Mutation Causing Familial Isolated Pituitary Adenoma Syndrome. ENDOCRINE REVIEWS. vol. 35,

Iacovazzo D, Morrison PJ, Foulkes W, Ross DS, Lugli F, Gabrovska P, Lucci-Cordisco E, De Marinis L et al.(2014). Four Families with RET-Mutation Negative Familial Medullary Thyroid Carcinoma: What Lies Beyond RET?. ENDOCRINE REVIEWS vol. 35, (3)

Butz H, Szabo PM, Igaz P, Czirjak S, Barry S, Liko I, Korbonits M, Racz K et al. (2014). Integrative Analysis of Chromosomal, Trancriptome, Proteomic and Mirnome Data Reveals Involvement of Impaired Developmental Processes in Clinically Non-Functional Pituitary Adenoma Formation. ENDOCRINE REVIEWS. vol. 35,

Schernthaner-Reiter MH, Trivellin G, Nesterova MV, Hernandez-Ramirez LC, Aflorei ED, Sierra MDLL, Stratakis CA, Korbonits M (2014). Interaction of AIP with the cAMP-Dependent Protein Kinase (PKA) Pathway and Its Role in Pituitary Tumor Formation. ENDOCRINE REVIEWS. vol. 35,

Hernandez-Ramirez LC, Gabrovska P, Denes J, Trivellin G, Radian S, Tilley D, Ferrau F, Akkers SA et al. (2014). Pituitary Adenomas Harboring AIP Mutations Exhibit Phenotype-Genotype Correlation, but No Association with the Germline FGFR4 G388R Variant or Somatic GNAS1 Mutations. ENDOCRINE REVIEWS. vol. 35,

Radian S, Gabrovska P, Holland B, Wallace H, Ryan AW, McGurren K, Stals K, Bussell A-M et al. (2014). Population Screening for the Irish Founder AIP Mutation R304*Reveals a Prevalence of 1/500 in the Local Population, While High Mutation Frequency Is Present Among Irish Familial and Sporadic Somatotropinoma Patients. ENDOCRINE REVIEWS. vol. 35,

Dworakowska D, Dudka D, Weitsman G, King PJ, Diaz-Cano SJ, Korbonits M, Grossman AB, Aylwin SJB et al.(2014). Simultaneous Targeting PI3K/Akt/mTOR and MEK/RAF/ERK Pathways Results in a Synergistic Anti-Proliferative Effect in an Adrenocortical Carcinoma Model. ENDOCRINE REVIEWS vol. 35, (3)

Soh LM, Druce M, Grossman AB, Differ A-M, Rajput L, Bitner-Glindzicz M, Korbonits M (2014). Strong Genotype-Phenotype Correlation in Pendred Syndrome Allows Reduced Endocrine Follow-up in Suitable Patients. ENDOCRINE REVIEWS. vol. 35,

Pernicova I, Korbonits M(2014). Metformin--mode of action and clinical implications for diabetes and cancer. Nat Rev Endocrinol vol. 10, (3) 143-156.

Stadler M, Tomann L, Storka A, Wolzt M, Peric S, Bieglmayer C, Pacini G, Dickson SL et al.(2014). Effects of smoking cessation on b-cell function, insulin sensitivity, body weight, and appetite. European Journal of Endocrinology vol. 170, (2) 219-227.

Stadler M, Krššák M, Jankovic D, Göbl C, Winhofer Y, Pacini G, Bischof M, Haidinger M et al.(2014). Fasting and postprandial liver glycogen content in patients with type 1 diabetes mellitus after successful pancreas-kidney transplantation with systemic venous insulin delivery. Clin Endocrinol (Oxf) vol. 80, (2) 208-213.

Nölting S, Giubellino A, Tayem Y, Young K, Lauseker M, Bullova P, Schovanek J, Anver M et al.(2014). Combination of 13-Cis retinoic acid and lovastatin: Marked antitumor potential in vivo in a pheochromocytoma allograft model in female athymic nude mice. Endocrinology vol. 155, (7) 2377-2390.

Tritos NA, Johannsson G, Korbonits M, Miller KK, Feldt-Rasmussen U, Yuen KCJ, King D, Mattsson AF et al.(2014). Effects of long-term growth hormone replacement in adults with growth hormone deficiency following cure of acromegaly: A KIMS analysis. Journal of Clinical Endocrinology and Metabolism vol. 99, (6) 2018-2029.

Aflorei ED, Korbonits M(2014). Epidemiology and etiopathogenesis of pituitary adenomas. Journal of Neuro-Oncology vol. 117, (3) 379-394.

Alband N, Korbonits M(2014). Familial pituitary tumors. vol. 124, 339-360.

Preda V, Korbonits M, Cudlip S, Karavitaki N, Grossman AB(2014). Low rate of germline AIP mutations in patients with apparently sporadic pituitary adenomas before the age of 40: A single-centre adult cohort. European Journal of Endocrinology vol. 171, (5) 659-666.

De Kock L, Sabbaghian N, Plourde F, Srivastava A, Weber E, Bouron-Dal Soglio D, Hamel N, Choi JH et al.(2014). Pituitary blastoma: A pathognomonic feature of germ-line DICER1 mutations. Acta Neuropathologica vol. 128, (1) 111-122.

Larkin SJ, Ferraù F, Karavitaki N, Hernández-Ramírez LC, Ansorge O, Grossman AB, Korbonits M(2014). Sequence analysis of the catalytic subunit of PKA in somatotroph adenomas. European Journal of Endocrinology vol. 171, (6) 705-710.

García EA, Trivellin G, Aflorei ED, Powell M, Grieve J, Alusi G, Pobereskin L, Shariati B et al.(2013). Characterization of snare proteins in human pituitary adenomas: Targeted secretion inhibitors as a new strategy for the treatment of acromegaly?. Journal of Clinical Endocrinology and Metabolism vol. 98, (12)

Kola B, Wittman G, Bodnár I, Amin F, Lim CT, Oláh M, Christ-Crain M, Lolli F et al.(2013). The CB1 receptor mediates the peripheral effects of ghrelin on AMPK activity but not on growth hormone release. FASEB J vol. 27, (12) 5112-5121.

Scerif M, Füzesi T, Thomas JD, Kola B, Grossman AB, Fekete C, Korbonits M(2013). CB1 receptor mediates the effects of glucocorticoids on AMPK activity in the hypothalamus. J Endocrinol vol. 219, (1) 79-88.

Rattenberry E, Vialard L, Yeung A, Bair H, McKay K, Jafri M, Canham N, Cole TR et al.(2013). A Comprehensive Next Generation Sequencing-Based Genetic Testing Strategy To Improve Diagnosis of Inherited Pheochromocytoma and Paraganglioma. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM vol. 98, (7) E1248-E1256.

Gadelha MR, Kasuki L, Korbonits M(2013). Novel pathway for somatostatin analogs in patients with acromegaly. TRENDS IN ENDOCRINOLOGY AND METABOLISM vol. 24, (5) 238-246.

Hernández-Ramírez LC, Korbonits M(2013). Familial Pituitary Adenomas. Pituitary Disorders: Diagnosis and Management,

Occhi G, Regazzo D, Trivellin G, Boaretto F, Ciato D, Bobisse S, Ferasin S, Cetani F et al.(2013). A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype. PLOS GENETICS vol. 9, (3) Article ARTN e1003350,

Javaid MR, Stone I, Grossman A, Korbonits M, Thomas J, Petersen S, Davies C (2013). CARDIAC MAGNETIC RESONANCE MYOCARDIAL FEATURE TRACKING: THE EFFECT OF TREATMENT IN PATIENTS WITH ADULT-ONSET GROWTH HORMONE DEFICIENCY AND ACROMEGALY. INTERNATIONAL JOURNAL OF CARDIOLOGY. vol. 163, S60-S60.

Lim CT, Kola B, Feltrin D, Perez-Tilve D, Tschöp MH, Grossman AB, Korbonits M(2013). Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism. Mol Cell Endocrinol vol. 365, (2) 303-308.

Kovács GL, Góth M, Rotondo F, Scheithauer BW, Carlsen E, Saadia A, Hubina E, Kovács L et al.(2013). ACTH-secreting Crooke cell carcinoma of the pituitary. Eur J Clin Invest vol. 43, (1) 20-26.

Williams F, Hunter S, Bradley L, Chahal HS, STORR HL, Akker SA, Kumar AV, Orme SM et al.(2013). Clinical experience in the screening and management of a large kindred with familial isolated pituitary adenoma due to an aryl hydrocarbon receptor interacting protein (AIP) mutation. Journal of Clinical Endocrinology and Metabolism vol. 99, (4) 1122-1131.

Gadelha MR, Trivellin G, Hernandez-Ramirez LC, Korbonits M(2013). Genetics of Pituitary Adenomas. ENDOCRINE TUMOR SYNDROMES AND THEIR GENETICS vol. 41, 111-140.

Gueorguiev M, Korbonits M(2013). Genetics of the ghrelin system. Endocr Dev vol. 25, 25-40.

Gadelha MR, Kasuki L, Dénes J, Trivellin G, Korbonits M(2013). MicroRNAs: Suggested role in pituitary adenoma pathogenesis. Journal of Endocrinological Investigation vol. 36, (10) 889-895.

Martucci F, Trivellin G, Korbonits M(2012). Familial isolated pituitary adenomas: an emerging clinical entity. J Endocrinol Invest vol. 35, (11) 1003-1014.

Guaraldi F, Corazzini V, Gallia GL, Grottoli S, Stals K, Dalantaeva N, Frohman LA, Korbonits M et al.(2012). Genetic analysis in a patient presenting with meningioma and familial isolated pituitary adenoma (FIPA) reveals selective involvement of the R81X mutation of the AIP gene in the pathogenesis of the pituitary tumor. Pituitary vol. 15, (1 SUPPL.)

Boguszewski CL, Fighera TM, Bornschein A, Marques FM, Denes J, Rattenbery E, Maher ER, Stals K et al.(2012). Genetic studies in a coexistence of acromegaly, pheochromocytoma, gastrointestinal stromal tumor (GIST) and thyroid follicular adenoma. ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA vol. 56, (8) 507-512.

Nölting S, Garcia E, Alusi G, Giubellino A, Pacak K, Korbonits M, Grossman AB(2012). Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines. J Mol Endocrinol vol. 49, (2) 79-96.

Trivellin G, Butz H, Delhove J, Igreja S, Chahal HS, Zivkovic V, McKay T, Patócs A et al.(2012). MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitro. Am J Physiol Endocrinol Metab vol. 303, (6) E708-E719.

Korbonits M, Storr H, Kumar AV(2012). Familial pituitary adenomas - who should be tested for AIP mutations?. Clin Endocrinol (Oxf) vol. 77, (3) 351-356.

Jeyabalan J, Shah M, Viollet B, Roux JP, Chavassieux P, Korbonits M, Chenu C(2012). Mice lacking AMP-activated protein kinase α1 catalytic subunit have increased bone remodelling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment. J Endocrinol vol. 214, (3) 349-358.

Marques MB, Jr R-OA, Guimaraes J, Nascimento GF, Anjos AP, Vilas-Boas WW, Santos RAS, Thomas JD et al.(2012). Modifications in basal and stress-induced hypothalamic AMP-activated protein kinase (AMPK) activity in rats chronically treated with an angiotensin II receptor blocker. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS vol. 15, (5) 554-561.

Thompson IR, Chand AN, King PJ, Ansorge O, Karavitaki N, Jones CA, Rahmutula D, Gardner DG et al.(2012). Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a role for C-type natriuretic peptide. Endocr Relat Cancer vol. 19, (4) 497-508.

Diggle CP, Parry DA, Logan CV, Laissue P, Rivera C, Martin Restrepo C, Fonseca DJ, Morgan JE et al.(2012). Prostaglandin transporter mutations cause pachydermoperiostosis with myelofibrosis. HUMAN MUTATION vol. 33, (8) 1175-1181.

Chahal HS, Trivellin G, Leontiou CA, Alband N, Fowkes RC, Tahir A, Igreja SC, Chapple JP et al.(2012). Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway. J Clin Endocrinol Metab vol. 97, (8) E1411-E1420.

Alexandraki KI, Munayem Khan M, Chahal HS, Dalantaeva NS, Trivellin G, Berney DM, Caron P, Popovic V et al.(2012). Oncogene-induced senescence in pituitary adenomas and carcinomas. Hormones (Athens) vol. 11, (3) 297-307.

Korbonits M(2012). Molecular biology of pituitary tumours. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION vol. 42, 49-50.

Butz H, Liko I, Czirjak S, Korbonits M, Racz K, Patocs A(2012). miR expression profile reveals alterations of G2/M transition of cell cycle in pituitary adenomas. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION vol. 42, 50-50.

Lim CT, Korbonits M(2012). Paediatric endocrine aspects of ghrelin. Pediatr Endocrinol Rev vol. 9, (3) 628-638.

Zemrak F, Thomas J, Dattani A, Burchell TR, Petersen SE, Grossman A, Korbonits M, Davies C (2012). Cardiovascular changes in patients with acromegaly assessed by CMR. J Cardiovasc Magn Reson. vol. 14 Suppl 1,

Dattani A, Thomas J, Zemrak F, Burchell TR, Petersen SE, Grossman A, Korbonits M, Davies C (2012). Cardiovascular changes in patients with adult-onset growth hormone deficiency assessed by CMR. J Cardiovasc Magn Reson. vol. 14 Suppl 1,

Noelting S, Garcia E, Alusi G, Korbonits M, Grossman A (2012). Combined Blockade of Several Signalling Pathways Shows Marked Anti-Tumor Potential in Two Novel Mouse Phaeochromocytoma Cell Lines. NEUROENDOCRINOLOGY. vol. 96, 10-11.

Scerif M, Kola B, Korbonits M(2012). Ghrelin regulation of AMPK in the hypothalamus and peripheral tissues. Ghrelin in Health and Disease,

Lim CT, Lolli F, Thomas JD, Kola B, Korbonits M(2012). Measurement of AMP-activated protein kinase activity and expression in response to ghrelin. Methods Enzymol vol. 514, 271-287.

Miljic P, Miljic D, Cain JW, Korbonits M, Popovic V(2012). Pathogenesis of vascular complications in Cushing's syndrome. HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM vol. 11, (1) 21-30.

Morgan RML, Hernández-Ramírez LC, Trivellin G, Zhou L, Roe SM, Korbonits M, Prodromou C(2012). Structure of the TPR domain of AIP: lack of client protein interaction with the C-terminal α-7 helix of the TPR domain of AIP is sufficient for pituitary adenoma predisposition. PLoS One vol. 7, (12)

Liu B, Garcia EA, Korbonits M(2011). Genetic studies on the ghrelin, growth hormone secretagogue receptor (GHSR) and ghrelin O-acyl transferase (GOAT) genes. Peptides vol. 32, (11) 2191-2207.

Cai W, Kramarova TV, Berg P, Korbonits M, Pongratz I(2011). The Immunophilin-Like Protein XAP2 Is a Negative Regulator of Estrogen Signaling through Interaction with Estrogen Receptor alpha. PLOS ONE vol. 6, (10) Article e25201,

Lim CT, Kola B, Korbonits M(2011). The ghrelin/GOAT/GHS-R system and energy metabolism. Rev Endocr Metab Disord vol. 12, (3) 173-186.

Trivellin G, Korbonits M(2011). AIP and its interacting partners. J Endocrinol vol. 210, (2) 137-155.

Scerif M, Goldstone AP, Korbonits M(2011). Ghrelin in obesity and endocrine diseases. Mol Cell Endocrinol vol. 340, (1) 15-25.

Butz H, Likó I, Czirják S, Igaz P, Korbonits M, Rácz K, Patócs A(2011). MicroRNA profile indicates downregulation of the TGFβ pathway in sporadic non-functioning pituitary adenomas. Pituitary vol. 14, (2) 112-124.

Stals K, Trivellin G, Korbonits M(2011). AIP Mutation in Pituitary Adenomas REPLY. NEW ENGL J MED vol. 364, (20) 1974-1975.

Stals K, Trivellin G, Korbonits M(2011). The authors and a colleague reply. New England Journal of Medicine vol. 364, (20) 1974-1975.

Shah M, Viollet B, Korbonits M, Chenu C (2011). Deletion of Amp-activated Protein Kinase (AMPK)-Alpha 1 catalytic subunit in mice impairs the in vivo response of bones to hormonal challenges. BONE. vol. 48, S96-S96.

Butz H, Liko I, Czirjak S, Igaz P, Beko G, Korbonits M, Racz K, Patocs A(2011). EXPRESSION OF A SUBSET OF MICRORNAS IN CLINICALLY NON-FUNCTIONING PITUITARY ADENOMAS CORRELATES WITH TUMOR SIZE. CLIN CHEM LAB MED vol. 49, S416-S416.

Alexandraki KI, Kaltsas GA, Vouliotis A-I, Papaioannou TG, Trisk L, Zilos A, Korbonits M, Besser GM et al.(2011). Specific electrocardiographic features associated with Cushing's disease. Clin Endocrinol (Oxf) vol. 74, (5) 558-564.

Dénes J, Korbonits M, Hubina E, Kovács GL, Kovács L, Görömbey Z, Czirják S, Góth M(2011). [Familial isolated pituitary adenoma syndrome]. Orv Hetil vol. 152, (18) 722-730.

Scerif M, Goldstone AP, Korbonits M(2011). Ghrelin in Obesity and Endocrine Diseases. Mol Cell Endocrinol

Chahal HS, Stals K, Unterländer M, Balding DJ, Thomas MG, Kumar AV, Besser GM, Atkinson AB et al.(2011). AIP mutation in pituitary adenomas in the 18th century and today. N Engl J Med vol. 364, (1) 43-50.

Chahal HS, Stals K, Unterlander M, Balding DJ, Thomas MG, Kumar AV, Besser GM, Atkinson AB et al.(2011). Brief Report: AIP Mutation in Pituitary Adenomas in the 18th Century and Today. NEW ENGL J MED vol. 364, (1) 43-50.

Chahal HS, Ansorge O, Karavitaki N, Leontiou CA, Carlsen E, Wass JA, Grossman AB, Korbonits M(2011). Somatostatin Analogue Treatment Increases AIP Protein Expression in Somatotroph Tumours from Patients with Acromegaly and in GH3 Cells in vitro. Horm Res Paediatr vol. 76 Suppl 1, 111-112.

Lim CT, Kola B, Grossman A, Korbonits M(2011). The expression of ghrelin O-acyltransferase (GOAT) in human tissues. Endocr J vol. 58, (8) 707-710.

Dworakowska D, Korbonits M, Aylwin S, McGregor A, Grossman AB(2011). The pathology of pituitary adenomas from a clinical perspective. Frontiers in Bioscience - Scholar vol. 3 S, (1) 105-116.

Dworakowska D, Korbonits M, Aylwin S, McGregor A, Grossman AB(2011). The pathology of pituitary adenomas from a clinical perspective. Front Biosci (Schol Ed) vol. 3, 105-116.

Grisouard J, Timper K, Radimerski TM, Frey DM, Peterli R, Kola B, Korbonits M, Herrmann P et al.(2010). Mechanisms of metformin action on glucose transport and metabolism in human adipocytes. BIOCHEM PHARMACOL vol. 80, (11) 1736-1745.

de Pinho LKJ, Neto LV, Wildemberg LEA, Moraes AB, Takiya CM, Frohman LA, Korbonits M, Gadelha MR(2010). Familial isolated pituitary adenomas experience at a single center: clinical importance of AIP mutation screening. ARQ BRAS ENDOCRINOL vol. 54, (8) 698-704.

Butz H, Likó I, Czirják S, Igaz P, Khan MM, Zivkovic V, Bálint K, Korbonits M et al.(2010). Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomas. J Clin Endocrinol Metab vol. 95, (10) E181-E191.

Ozfirat Z, Korbonits M(2010). AIP gene and familial isolated pituitary adenomas. Mol Cell Endocrinol vol. 326, (1-2) 71-79.

Musat M, Morris DG, Korbonits M, Grossman AB(2010). Cyclins and their related proteins in pituitary tumourigenesis. MOL CELL ENDOCRINOL vol. 326, (1-2) 25-29.

Cain JW, Miljic D, Popovic V, Korbonits M(2010). Role of the aryl hydrocarbon receptor-interacting protein in familial isolated pituitary adenoma. Expert Review of Endocrinology and Metabolism vol. 5, (5) 681-695.

Dénes J, Korbonits M, Hubina E, Góth M(2010). [Treatment of acromegaly]. Orv Hetil vol. 151, (34) 1384-1393.

Langouche L, Vander Perre S, Thiessen S, Gunst J, Hermans G, D'Hoore A, Kola B, Korbonits M et al.(2010). Alterations in Adipose Tissue during Critical Illness An Adaptive and Protective Response?. AM J RESP CRIT CARE vol. 182, (4) 507-516.

Shah M, Kola B, Bataveljic A, Arnett TR, Viollet B, Saxon L, Korbonits M, Chenu C(2010). AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass. BONE vol. 47, (2) 309-319.

Igreja S, Chahal HS, King P, Bolger GB, Srirangalingam U, Guasti L, Chapple JP, Trivellin G et al.(2010). Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families. Hum Mutat vol. 31, (8) 950-960.

Stilling G, Sun ZF, Zhang SY, Jin L, Righi A, Gabor K, Korbonits M, Scheithauer BW et al.(2010). MicroRNA expression in ACTH-producing pituitary tumors: up-regulation of microRNA-122 and-493 in pituitary carcinomas. ENDOCRINE vol. 38, (1) 67-75.

Chahal HS, Chapple JP, Frohman LA, Grossman AB, Korbonits M(2010). Clinical, genetic and molecular characterization of patients with familial isolated pituitary adenomas (FIPA). Trends Endocrinol Metab vol. 21, (7) 419-427.

Chahal HS, Alband N, Ansorge O, Karavitaki N, Carlsen E, Wass JAH, Grossman AB, Korbonits M (2010). AIP Mediates the Effects of Somatostatin Analogues in Acromegaly - Evidence from Clinical and Experimental Studies. ENDOCRINE REVIEWS. vol. 31,

Righi A, Zhang SY, Jin L, Scheithauer BW, Kovacs K, Kovacs G, Goth MI, Korbonits M et al.(2010). Analysis of IMP3 Expression in Normal and Neoplastic Human Pituitary Tissues. ENDOCR PATHOL vol. 21, (1) 25-31.

Gadelha MR, Kasuki L, Neto LV, Wildemberg LEA, Gasparetto EL, Marcondes J, Takiya CM, Korbonits M et al.(2010). Pathogenesis of GH-secreting adenomas. ENDOCR J vol. 57, S282-S282.

Lim CT, Kola B, Korbonits M(2010). AMPK as a mediator of hormonal signalling. J Mol Endocrinol vol. 44, (2) 87-97.

Lim CT, Kola B, Korbonits M, Grossman AB(2010). Ghrelin's role as a major regulator of appetite and its other functions in neuroendocrinology. Prog Brain Res vol. 182, 189-205.

Tahir A, Chahal HS, Korbonits M(2010). Molecular genetics of the aip gene in familial pituitary tumorigenesis. Prog Brain Res vol. 182, 229-253.

Dworakowska D, Wlodek E, Leontiou CA, Igreja S, Cakir M, Teng M, Prodromou N, Góth MI et al.(2009). Activation of RAF/MEK/ERK and PI3K/AKT/mTOR pathways in pituitary adenomas and their effects on downstream effectors. Endocr Relat Cancer vol. 16, (4) 1329-1338.

Chahal HS, Ajith Kumar VA, Korbonits M(2009). Familial isolated pituitary adenomas. US Endocrinology vol. 5, 104-107.

Butler H, Korbonits M(2009). Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists. Eur J Endocrinol vol. 161, (5) 655-662.

Grisouard J, Kinter DS, Radimerski T, Timper K, Frey DM, Kola B, Korbonits M, Zulewski H et al. (2009). AMP-activated protein kinase (AMPK) modulates lipopolysaccharide (LPS)-induced cytokine expression and lipolysis in human adipocytes. DIABETOLOGIA. vol. 52, S253-S253.

Kola B, Korbonits M(2009). Shedding light on the intricate puzzle of ghrelin's effects on appetite regulation. J Endocrinol vol. 202, (2) 191-198.

Garcia EA, King P, Sidhu K, Ohgusu H, Walley A, Lecoeur C, Gueorguiev M, Khalaf S et al.(2009). The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes. Eur J Endocrinol vol. 161, (2) 307-315.

Gueorguiev M, Lecoeur C, Meyre D, Benzinou M, Mein CA, Hinney A, Vatin V, Weill J et al.(2009). Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity. Obesity (Silver Spring) vol. 17, (4) 745-754.

Korbonits M, Carlsen E (2009). Recent clinical and pathophysiological advances in non-functioning pituitary adenomas. Horm Res. vol. 71 Suppl 2, 123-130.

Igreja S, Chahal HS, Akker SA, Gueorguiev M, Popovic V, Damjanovic S, Burman P, Wass JA et al.(2009). Assessment of p27 (cyclin-dependent kinase inhibitor 1B) and aryl hydrocarbon receptor-interacting protein (AIP) genes in multiple endocrine neoplasia (MEN1) syndrome patients without any detectable MEN1 gene mutations. Clin Endocrinol (Oxf) vol. 70, (2) 259-264.

Gueorguiev M, Lecoeur C, Benzinou M, Mein CA, Meyre D, Vatin V, Weill J, Heude B et al.(2009). A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature. Ann Hum Genet vol. 73, (1) 1-9.

Leontiou CA, Gueorguiev M, Hassan S, van der Spuy J, Lolli F, Stolbrink M, Christian HC, Wray J et al. (2009). AIP, a Protein Mutated in Familial Acromegaly, Plays a Role in the Regulation of Cell Proliferation and Shows Cell-Type Specific Subcellular Localisation. HORMONE RESEARCH. vol. 71, 149-150.

Musat M, Korbonits M, Grossman A(2009). STOP AKTING TO TREAT ENDOCRINE TUMOURS. ACTA ENDOCRINOL vol. 5, (1) 131-142.

Kola B, Christ-Crain M, Lolli F, Arnaldi G, Giacchetti G, Boscaro M, Grossman AB, Korbonits M(2008). Changes in Adenosine 5 '-Monophosphate-Activated Protein Kinase as a Mechanism of Visceral Obesity in Cushing's Syndrome. J CLIN ENDOCR METAB vol. 93, (12) 4969-4973.

Ribeiro-Oliveira A, Franchi G, Kola B, Dalino P, Pinheiro SVB, Salahuddin N, Musat M, Góth MI et al.(2008). Protein western array analysis in human pituitary tumours: insights and limitations. Endocr Relat Cancer vol. 15, (4) 1099-1114.

Gibson C, Korbonits M(2008). The Yin and Yang of the Ghrelin gene products. Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry vol. 8, (4) 292-302.

Ribeiro-Oliveira A, Korbonits M, Grossman AB(2008). The potential role of D-2 dopamine receptors as a target in the management of neuroendocrine tumors. CANCER BIOL THER vol. 7, (12) 1979-1981.

Garcia EA, Heude B, Petry CJ, Gueorguiev M, Hassan-Smith ZK, Spanou A, Ring SM, Dunger DB et al.(2008). Ghrelin receptor gene polymorphisms and body size in children and adults. J CLIN ENDOCR METAB vol. 93, (10) 4158-4161.

Grisouard J, Radimerski T, Kinter DS, Zulewski H, Kola B, Korbonits M, Muller B, Keller U et al.(2008). Effects of the AMPK activators AICAR and metformin on basal and insulin-induced glucose-uptake in human adipocytes. DIABETOLOGIA vol. 51, S313-S314.

Shah M, Kola B, Sunters A, Korbonits M, Chenu CC (2008). Neuroendocrine Activation of AMP-activated Protein Kinase (AMPK) in Osteoblasts. JOURNAL OF BONE AND MINERAL RESEARCH. vol. 23, S251-S251.

Grozinsky-Glasberg S, Shimon I, Korbonits M, Grossman AB(2008). Somatostatin analogues in the control of neuroendocrine tumours: efficacy and mechanisms. ENDOCR-RELAT CANCER vol. 15, (3) 701-720.

Varga M, Rajczy K, Telkes G, Hídvégi M, Péter A, Remport A, Korbonits M, Fazakas J et al.(2008). HLA-DQ3 is a probable risk factor for CMV infection in high-risk kidney transplant patients. Nephrol Dial Transplant vol. 23, (8) 2673-2678.

Christ-Crain M, Kola B, Lolli F, Fekete C, Seboek D, Wittmann G, Feltrin D, Igreja SC et al.(2008). AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing's syndrome. FASEB J vol. 22, (6) 1672-1683.

Leontiou CA, Gueorguiev M, van der Spuy J, Quinton R, Lolli F, Hassan S, Chahal HS, Igreja SC et al.(2008). The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas. J Clin Endocrinol Metab vol. 93, (6) 2390-2401.

Grozinsky-Glasberg S, Grossman AB, Korbonits M(2008). The role of somatostatin analogues in the treatment of neuroendocrine tumours. Mol Cell Endocrinol vol. 286, (1-2) 238-250.

Zavarella S, Petrone A, Zampetti S, Gueorguiev M, Spoletini M, Mein CA, Leto G, Korbonits M et al.(2008). A new variation in the promoter region, the -604 C > T, and the Leu72Met polymorphism of the ghrelin gene are associated with protection to insulin resistance. INT J OBESITY vol. 32, (4) 663-668.

Kola B, Farkas I, Christ-Crain M, Wittmann G, Lolli F, Amin F, Harvey-White J, Liposits Z et al.(2008). The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system. PLoS One vol. 3, (3)

Shah M, Kola B, Sunters A, Korbonits M, Chenu C(2008). AMP-activated protein kinase (AMPK) plays a role in osteoblast function. CALCIFIED TISSUE INT vol. 82, S117-S117.

van Thuijl H, Kola B, Korbonits M(2008). Appetite and metabolic effects of ghrelin and cannabinoids: involvement of AMP-activated protein kinase. Vitam Horm vol. 77, 121-148.

Korbonits M(2008). Obesity and metabolism. Preface. Front Horm Res vol. 36,

Grozinsky-Glasberg S, Franchi G, Teng M, Leontiou CA, Ribeiro de Oliveira A, Dalino P, Salahuddin N, Korbonits M et al.(2008). Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line. Neuroendocrinology vol. 87, (3) 168-181.

Kola B, Grossman AB, Korbonits M(2008). The role of AMP-activated protein kinase in obesity. Front Horm Res vol. 36, 198-211.

Samsuddin S, Glyn M, Kola B, Korbonits M, Holness MJ, Sugden MC (2007). A direct effect of ghrelin to augment cardiac AMPK activity is compromised by hyperglycaemia following ischaemia/reperfusion. DIABETOLOGIA. vol. 50, S490-S490.

Radimerski T, Seboek D, Kola B, Linscheid P, Zulewski H, Grossman A, Keller U, Muller B et al. (2007). Differential effects of 5AMP-activated protein kinase (AMPK) activation by metformin and AICAR on glucose uptake and lipolysis in human adipocytes. DIABETOLOGIA. vol. 50, S232-S232.

Christ-Crain M, Kola B, Lolli F, Grossman AB, Korbonits M(2007). The role of AMP-activated protein kinase in the metabolic syndrome. OBES METAB-MILAN vol. 3, (3) 143-154.

Korbonits M, Blaine D, Elia M, Powell-Tuck J(2007). Metabolic and hormonal changes during the refeeding period of prolonged fasting. EUR J ENDOCRINOL vol. 157, (2) 157-166.

Gueorguiev M, Wiltshire S, Garcia EA, Mein C, Lecoeur C, Kristen B, Allotey R, Hattersley AT et al.(2007). Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes. J CLIN ENDOCR METAB vol. 92, (6) 2201-2204.

Ewing I, Pedder-Smith S, Franchi G, Ruscica M, Emery M, Vax V, Garcia E, Czirják S et al.(2007). A mutation and expression analysis of the oncogene BRAF in pituitary adenomas. Clin Endocrinol (Oxf) vol. 66, (3) 348-352.

Leontiou CA, Franchi G, Korbonits M(2007). Ghrelin in neuroendocrine organs and tumours. Pituitary vol. 10, (3) 213-225.

Higgins SC, Gueorguiev M, Korbonits M(2007). Ghrelin, the peripheral hunger hormone. Ann Med vol. 39, (2) 116-136.

Swales KE, Korbonits M, Carpenter R, Walsh DT, Warner TD, Bishop-Bailey D(2006). The farnesoid X receptor is expressed in breast cancer and regulates apoptosis and aromatase expression. Cancer Res vol. 66, (20) 10120-10126.

Christ-Crain M, Stoeckli R, Ernst A, Morgenthaler NG, Bilz S, Korbonits M, Struck J, Bergmann A et al.(2006). Effect of gastric bypass and gastric banding on proneurotensin levels in morbidly obese patients. J Clin Endocrinol Metab vol. 91, (9) 3544-3547.

Jackson JM, Blaine D, Powell-Tuck J, Korbonits M, Carey A, Elia M(2006). Macro- and micronutrient losses and nutritional status resulting from 44 days of total fasting in a non-obese man. NUTRITION vol. 22, (9) 889-897.

Emery MN, Leontiou C, Bonner SE, Merulli C, Nanzer AM, Musat M, Galloway M, Powell M et al.(2006). PPAR-gamma expression in pituitary tumours and the functional activity of the glitazones: evidence that any anti-proliferative effect of the glitazones is independent of the PPAR-gamma receptor. CLIN ENDOCRINOL vol. 65, (3) 389-395.

Zampetti S, Zavarella S, Petrone A, Spoletini M, Gueorguiev M, Garcia E, Leto G, Potenziani S et al. (2006). The role of Leu72Met and-604 C > T polymorphisms of the ghrelin gene on insulin resistance in Italian population. DIABETOLOGIA. vol. 49, 225-226.

Hubina E, Nanzer AM, Hanson MR, Ciccarelli E, Losa M, Gaia D, Papotti M, Terreni MR et al.(2006). Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours. Eur J Endocrinol vol. 155, (2) 371-379.

Kola B, Boscaro M, Rutter GA, Grossman AB, Korbonits M(2006). Expanding role of AMPK in endocrinology. TRENDS ENDOCRIN MET vol. 17, (5) 205-215.

García EA, Korbonits M(2006). Ghrelin and cardiovascular health. Curr Opin Pharmacol vol. 6, (2) 142-147.

Góth M, Hubina E, Korbonits M(2005). Relationship between the hypothalamo-pituitary-adrenal axis and the metabolic syndrome. Orvosi Hetilap vol. 146, (2) 51-55.

Korbonits M, Blaine D, Elia M, Powell-Tuck J(2005). Refeeding David Blaine--studies after a 44-day fast. N Engl J Med vol. 353, (21) 2306-2307.

Bonner SE, Morris DG, Korbonits M, Laban CA, McCarthy K, Al-Mufti R (2005). The roles of CyclinE, Jab1 and archipelago in breast cancer cell cycle dysregulation. BRITISH JOURNAL OF SURGERY. vol. 92, 1309-1309.

Dahia PLM, Ross KN, Wright ME, Hayashida CY, Santagata S, Barontini M, Kung AL, Sanso G et al.(2005). A HIF1 alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. PLOS GENET vol. 1, (1) Article e8, 72-80.

Kola B, Hubina E, Tucci SA, Kirkham TC, Garcia EA, Mitchell SE, Williams LM, Hawley SA et al.(2005). Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J BIOL CHEM vol. 280, (26) 25196-25201.

Morris DG, Musat M, Czirják S, Hanzély Z, Lillington DM, Korbonits M, Grossman AB(2005). Differential gene expression in pituitary adenomas by oligonucleotide array analysis. Eur J Endocrinol vol. 153, (1) 143-151.

Hubina E, Góth M, Korbonits M(2005). [Ghrelin--a hormone with multiple functions]. Orv Hetil vol. 146, (25) 1345-1351.

Musat M, Korbonits M, Kola B, Borboli N, Hanson MR, Nanzer AM, Grigson J, Jordan S et al.(2005). Enhanced protein kinase B/Akt signalling in pituitary tumours. ENDOCR-RELAT CANCER vol. 12, (2) 423-433.

Goldstone AP, Patterson M, Kalingag N, Ghatei MA, Brynes AE, Bloom SR, Grossman AB, Korbonits M(2005). Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma. J Clin Endocrinol Metab vol. 90, (5) 2681-2690.

Góth M, Hubina E, Korbonits M(2005). [Correlations between the hypothalamo-pituitary-adrenal axis and the metabolic syndrome]. Orv Hetil vol. 146, (2) 51-55.

KORBONITS MJ, Thorner MO, Gaylinn BD, Nass R(2005). Growth Hormone–Releasing Hormone, Ghrelin and Growth Hormone Secretagogues: Basic Physiology and Clinical Implications. De Groot Clinical Endocrinology Elsevier

Korbonits M, GROSSMAN AB, Hubina E, Khalaf S, Gaia D, Nagy G, Czirjak S, Papotti M et al.(2005). Investigation of the intracellular effects of somatostatin analogs in pituitary adenomas. J Clin Endocrinol Metab

Hubina E, Ruscica M, Nanzer AM, Czirják S, Góth MI, Grossman AB, Korbonits M(2005). Novel molecular aspects of pituitary adenomas. J Endocrinol Invest vol. 28, (11 Suppl International) 87-92.

KORBONITS MJ, Barnes PJ, Korbonits D, Crispino N, Patel HJ, Birrell MA, Belvisi MG, Usmani OS(2005). Theobromine inhibits sensory nerve activation and cough. FASEB J vol. 19, 231-233`.

Korbonits M, Kipnes M, Grossman AB(2004). Striant (TM) SR: a novel, effective and convenient testosterone therapy for male hypogonadism. INT J CLIN PRACT vol. 58, (11) 1073-1080.

Tucci SA, Rogers EK, Korbonits M, Kirkham TC(2004). The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin. BRIT J PHARMACOL vol. 143, (5) 520-523.

Usmani OS, Belvisi MG, Patel HJ, Crispino N, Birrell MA, Korbonits M, Korbonits D, Barnes PJ(2004). Theobromine inhibits sensory nerve activation and cough. FASEB J vol. 18, (14) 231-+.

Nanzer AM, Khalaf S, Mozid AM, Fowkes RC, Patel MV, Burrin JM, Grossman AB, Korbonits M(2004). Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway. Eur J Endocrinol vol. 151, (2) 233-240.

Korbonits M, Grossman AB(2004). Ghrelin: update on a novel hormonal system. EUR J ENDOCRINOL vol. 151, S67-S70.

Gueorguiev M, Lecoeur C, Froguel R, Grossman AB, Korbonits M (2004). Mutational analysis of ghrelin and the growth hormone secretagogue receptor. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. vol. 7, S56-S56.

Korbonits M, Slawik M, Cullen D, Ross RJ, Stalla G, Schneider H, Reincke M, Bouloux PM et al.(2004). A comparison of a novel testosterone bioadhesive buccal system, striant, with a testosterone adhesive patch in hypogonadal males. J Clin Endocrinol Metab vol. 89, (5) 2039-2043.

Góth M, Korbonits M(2004). [Therapy in acromegaly]. Orv Hetil vol. 145, (16) 867-871.

Goldstone AP, Thomas EL, Brynes AE, Castroman G, Edwards R, Ghatei MA, Frost G, Holland AJ et al.(2004). Elevated fasting plasma ghrelin in prader-willi syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance. J Clin Endocrinol Metab vol. 89, (4) 1718-1726.

Korbonits M, Goldstone AP, Gueorguiev M, Grossman AB(2004). Ghrelin - a hormone with multiple functions. FRONT NEUROENDOCRIN vol. 25, (1) 27-68.

KORBONITS MJ, Hubina E, Goth MI(2004). Aetiology and demography of patients with GH deficiency in KIMS. Growth hormone deficiency in Adults - KIMS 10 years Anonymous

Grossman AB, Korbonits M(2004). Akting and cycling: a tale of the pituitary. Horm Res vol. 62 Suppl 3, 117-123.

Bonner SE, Morris DG, Korbonits M, Laban CA, McCarthy K, Al-Mufti R, Grossman AB, Carpenter R (2004). Cell cycle dysregulation in breast cancer - the roles of Jab1 and Archipelago. BREAST CANCER RESEARCH AND TREATMENT. vol. 88, S180-S180.

Musat M, Vax VV, Borboli N, Gueorguiev M, Bonner S, Korbonits M, Grossman AB(2004). Cell cycle dysregulation in pituitary oncogenesis. FRONT HORM RES vol. 32, 34-62.

Vax V, Goncharov N, Kadashev B, Kasumova S, Marova E, Dedov I, Korbonits M, Grossman AB et al. (2004). Gonadotropinomas & non-functioning pituitary tumours in males. PROCEEDINGS OF THE 12TH INTERNATIONAL CONGRESS OF ENDOCRINOLOGY. 413-419.

KORBONITS MJ, Grossman AB(2004). Non-growth hormone endocrine actions of ghrelin. Ghrelin and growth hormone secretagogues73-88.

Korbonits M, Morris DG, Nanzer A, Kola B, Grossman AB(2004). Role of regulatory factors in pituitary tumour formation. Front Horm Res vol. 32, 63-95.

Morris DG, Kola B, Borboli N, Kaltsas GA, Gueorguiev M, McNicol AM, Ferrier R, Jones TH et al.(2003). Identification of adrenocorticotropin receptor messenger ribonucleic acid in the human pituitary and its loss of expression in pituitary adenomas. J Clin Endocrinol Metab vol. 88, (12) 6080-6087.

Kola B, Korbonits M, Diaz-Cano S, Kaltsas G, Morris DG, Jordan S, Metherell L, Powell M et al.(2003). Reduced expression of the growth hormone and type 1 insulin-like growth factor receptors in human somatotroph tumours and an analysis of possible mutations of the growth hormone receptor. Clin Endocrinol (Oxf) vol. 59, (3) 328-338.

Vax VV, Gueorguiev M, Dedov II, Grossman AB, Korbonits M(2003). The Krüppel-like transcription factor 6 gene in sporadic pituitary tumours. Endocr Relat Cancer vol. 10, (3) 397-402.

Vax VV, Bibi R, Diaz-Cano S, Gueorguiev M, Kola B, Borboli N, Bressac-de Paillerets B, Walker GJ et al.(2003). Activating point mutations in cyclin-dependent kinase 4 are not seen in sporadic pituitary adenomas, insulinomas or Leydig cell tumours. J Endocrinol vol. 178, (2) 301-310.

Mozid AM, Tringali G, Forsling ML, Hendricks MS, Ajodha S, Edwards R, Navarra P, Grossman AB et al.(2003). Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin. Horm Metab Res vol. 35, (8) 455-459.

Orkin RD, New DI, Norman D, Chew SL, Clark AJL, Grossman AB, Korbonits M(2003). Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro. J ENDOCRINOL INVEST vol. 26, (8) 743-747.

Svensson J, Monson JP, Vetter T, Hansen TK, Savine R, Kann P, Bex M, Reincke M et al.(2003). Oral administration of the growth hormone secretagogue NN703 in adult patients with growth hormone deficiency. CLIN ENDOCRINOL vol. 58, (5) 572-580.

KORBONITS MJ, Grossman AB, Kola B, Gueorguiev M, Musat M, Poiana C, Dumitrache C, Pyle M(2003). Expression of the F-box protein Skp-2 in normal and tumorous pituitary. Pituitary vol. 5, 235-242.

KORBONITS MJ, Grossman AB, Bandeira F, Guimaraes AC(2003). Hyperprolactinaemia. Endocrinology and Diabetes105-116.

Pyle ME, Korbonits M, Gueorguiev M, Jordan S, Kola B, Morris DG, Meinhardt A, Powell MP et al.(2003). Macrophage migration inhibitory factor expression is increased in pituitary adenoma cell nuclei. J Endocrinol vol. 176, (1) 103-110.

Kaltsas GA, Kola B, Borboli N, Morris DG, Gueorguiev M, Swords FM, Czirják S, Kirschner LS et al.(2002). Sequence analysis of the PRKAR1A gene in sporadic somatotroph and other pituitary tumours. Clin Endocrinol (Oxf) vol. 57, (4) 443-448.

Korbonits M, Gueorguiev M, O'Grady E, Lecoeur C, Swan DC, Mein CA, Weill J, Grossman AB et al.(2002). A variation in the ghrelin gene increases weight and decreases insulin secretion in tall, obese children. J Clin Endocrinol Metab vol. 87, (8) 4005-4008.

Gueorguiev M, Korbonits M, O'Grady E, Lecoeur C, Grossman AB, Froguel P (2002). Mutation in the ghrelin gene associated with increase in body weight and reduction of insulin secretion in tall, obese children. DIABETOLOGIA. vol. 45, A176-A176.

Korbonits M, Chahal HS, Kaltsas G, Jordan S, Urmanova Y, Khalimova Z, Harris PE, Farrell WE et al.(2002). Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors. J Clin Endocrinol Metab vol. 87, (6) 2635-2643.

Gnanapavan S, Kola B, Bustin SA, Morris DG, McGee P, Fairclough P, Bhattacharya S, Carpenter R et al.(2002). The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J CLIN ENDOCR METAB vol. 87, (6) 2988-2991.

Newell-Price J, Morris DG, Drake WM, Korbonits M, Monson JP, Besser GM, Grossman AB(2002). Optimal response criteria for the human CRH test in the differential diagnosis of ACTH-dependent Cushing's syndrome. J CLIN ENDOCR METAB vol. 87, (4) 1640-1645.

Isidori AM, Kaltsas GA, Korbonits M, Pyle M, Gueorguiev M, Meinhardt A, Metz C, Petrovsky N et al.(2002). Response of serum macrophage migration inhibitory factor levels to stimulation or suppression of the hypothalamo-pituitary-adrenal axis in normal subjects and patients with Cushing's disease. J Clin Endocrinol Metab vol. 87, (4) 1834-1840.

Musat M, Korbonits M, Pyle M, Gueorguiev M, Kola B, Morris DG, Powell M, Dumitrache C et al.(2002). The expression of the F-box protein Skp2 is negatively associated with p27 expression in human pituitary tumors. Pituitary vol. 5, (4) 235-242.

KORBONITS MJ(2002). Tumours and Humors. Central and Peripheral Mechanisms in Pituitary Disease vol. 87, 201-218.

Korbonits M, Bujalska I, Shimojo M, Nobes J, Jordan S, Grossman AB, Stewart PM(2001). Expression of 11 beta-hydroxysteroid dehydrogenase isoenzymes in the human pituitary: Induction of the type 2 enzyme in corticotropinomas and other pituitary tumors. J CLIN ENDOCR METAB vol. 86, (6) 2728-2733.

Korbonits M, Chitnis MM, Gueorguiev M, Norman D, Rosenfelder N, Suliman M, Jones TH, Noonan K et al.(2001). The release of leptin and its effect on hormone release from human pituitary adenomas. Clin Endocrinol (Oxf) vol. 54, (6) 781-789.

Kaltsas G, Korbonits M, Heintz E, Mukherjee JJ, Jenkins PJ, Chew SL, Reznek R, Monson JP et al.(2001). Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors. J CLIN ENDOCR METAB vol. 86, (2) 895-902.

Korbonits M, Kojima M, Kangawa K, Grossman AB(2001). Presence of ghrelin in normal and adenomatous human pituitary. Endocrine vol. 14, (1) 101-104.

Korbonits M, Bustin SA, Kojima M, Jordan S, Adams EF, Lowe DG, Kangawa K, Grossman AB(2001). The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors. J Clin Endocrinol Metab vol. 86, (2) 881-887.

KORBONITS MJ, Grossman AB, Bonthron DT, Barlier A, Jacquet P, Enjalbert A, Hayward BE(2001). Imprinting of the G(s)alpha gene GNAS1 in the pathogenesis of acromegaly. J Clin Invest vol. 107, R31-R36.

KORBONITS MJ, Gueorguiev M, Goth MI(2001). Leptin and puberty - a review. Pituitary vol. 4, (1-2) 79-86.

Korbonits M, Chitnis MM, Gueorguiev M, Jordan S, Norman D, Kaltsas G, Burrin JM, Grossman AB(2001). Leptin in pituitary adenomas--a novel paracrine regulatory system. Pituitary vol. 4, (1-2) 49-55.

Skelly RH, Korbonits M, Grossman A, Besser GM, Monson JP, Geddes JF, Burrin JM(2000). Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased α-subunit secretion. Journal of Clinical Endocrinology and Metabolism vol. 85, (7) 2537-2542.

Kaltsas GA, Korbonits M, Isidori AM, Webb JAW, Trainer PJ, Monson JP, Besser GM, Grossman AB(2000). How common are polycystic ovaries and the polycystic ovarian syndrome in women with Cushing's syndrome?. Clinical Endocrinology vol. 53, (4) 493-500.

Putignano P, Kaltsas GA, Korbonits M, Jenkins PJ, Monson JP, Besser GM, Grossman AB(2000). Alterations in serum protein levels in patients with Cushing's syndrome before and after successful treatment. Journal of Clinical Endocrinology and Metabolism vol. 85, (9) 3309-3312.

Jordan S, Lidhar K, Korbonits M, Lowe DG, Grossman AB(2000). Cyclin D and cyclin E expression in normal and adenomatous pituitary. European Journal of Endocrinology vol. 143, (1)

Korbonits M, Grossman AB(2000). Drug-induced hyperprolactinaemia. Prescribers' Journal vol. 40, (2) 157-164.

Korbonits M, Kaltsas G, Perry LA, Grossman AB, Monson JP, Besser GM, Trainer PJ(1999). Hexarelin as a test of pituitary reserve in patients with pituitary disease. Clinical Endocrinology vol. 51, (3) 369-375.

Korbonits M, Little JA, Forsling ML, Tringali G, Costa A, Navarra P, Trainer PJ, Grossman AB(1999). The effect of growth hormone secretagogues and neuropeptide Y on hypothalamic hormone release from acute rat hypothalamic explants. Journal of Neuroendocrinology vol. 11, (7) 521-528.

Satta MA, Korbonits M, Jacobs RA, Bolden-Dwinfour DA, Kaltsas GA, Vangeli V, Adams E, Fahlbusch R et al.(1999). Expression of menin gene mRNA in pituitary tumours. European Journal of Endocrinology vol. 140, (4) 358-361.

Lidhar K, Korbonits M, Jordan S, Khalimova Z, Kaltsas G, Lu X, Clayton RN, Jenkins PJ et al.(1999). Low expression of the cell cycle inhibitor p27(kip1) in normal corticotroph cells, corticotroph tumors, and malignant pituitary tumors. Journal of Clinical Endocrinology and Metabolism vol. 84, (10) 3823-3830.

Korbonits M, Kaltsas G, Perry LA, Putignano P, Grossman AB, Besser GM, Trainer PJ(1999). The growth hormone secretagogue hexarelin stimulates the hypothalamo-pituitary-adrenal axis via arginine vasopressin. Journal of Clinical Endocrinology and Metabolism vol. 84, (7) 2489-2495.

Korbonits M, Ciccarelli E, Ghigo E, Grossman AB (1999). The growth hormone secretagogue receptor. Growth Hormone and IGF Research. vol. 9, 93-99.

Korbonits M(1998). Leptin and the thyroid - A puzzle with missing pieces. Clinical Endocrinology vol. 49, (5) 569-572.

Korbonits M, Jacobs RA, Aylwin SJB, Burrin JM, Dahia PLM, Monson JP, Honegger J, Fahlbush R et al.(1998). Expression of the growth hormone secretagogue receptor in pituitary adenomas and other neuroendocrine tumors. Journal of Clinical Endocrinology and Metabolism vol. 83, (10) 3624-3630.

Trainer PJ, Woods RJ, Korbonits M, Popovic V, Stewart PM, Lowry PJ, Grossman AB(1998). The pathophysiology of circulating corticotropin-releasing hormone- binding protein levels in the human. Journal of Clinical Endocrinology and Metabolism vol. 83, (5) 1611-1614.

Korbonits M, Trainer PJ, Little JA, Edwards R, Kopelman PG, Besser GM, Svec F, Grossman AB(1997). Leptin levels do not change acutely with food administration in normal or obese subjects, but are negatively correlated with pituitary-adrenal activity. Clinical Endocrinology vol. 46, (6) 751-757.

Savage MO, Korbonits M, Grossman AB(1996). Intérêt clinique des neuropeptides GHRH et GHRP. Archives de Pediatrie vol. 3, (SUPPL. 1)

Korbonits M, Little JA, Camacho-Hubner C, Trainer PJ, Besser GM, Grossman AB(1996). Insulin-like growth factor-I and -II in combination inhibit the release of growth hormone-releasing hormone from the rat hypothalamus in vitro. Growth Regulation vol. 6, (2) 110-120.

Korbonits M, Besser M(1996). Diagnosis of growth hormone deficiency in adults. Hormone Research in Paediatrics vol. 46, (4-5) 174-182.

Korbonits M, Trainer PJ, Nelson ML, Howse I, Kopelman PG, Besser GM, Grossman AB, Svec F(1996). Differential stimulation of cortisol and dehydroepiandrosterone levels by food in obese and normal subjects: Relation to body fat distribution. Clinical Endocrinology vol. 45, (6) 699-706.

Korbonits M, Grossman AB(1996). Growth hormone-releasing peptides (GHRP) and their analogues. Orvosi hetilap vol. 137, (45) 2503-2509.

Korbonits M, Trainer PJ, Fanciulli G, Oliva O, Pala A, Dettori A, Besser M, Delitala G et al.(1996). L-Arginine is unlikely to exert neuroendocrine effects in humans via the generation of nitric oxide. European Journal of Endocrinology vol. 135, (5) 543-547.

Korbonits M, Trainer PJ, Edwards R, Besser GM, Grossman AB(1995). Benzodiazepines attenuate the pituitary-adrenal responses to corticotrophin-releasing hormone in healthy volunteers, but not in patients with Cushing's syndrome. Clinical Endocrinology vol. 43, (1) 29-35.

Korbonits M, Grossman AB(1995). Growth hormone-releasing peptide and its analogues. Novel stimuli to growth hormone release. Trends in Endocrinology and Metabolism vol. 6, (2) 43-49.

Korbonits M, Trainer PJ, Besser CM(1995). The effect of an opiate antagonist on the hormonal changes induced by hexarelin. Clinical Endocrinology vol. 43, (3) 365-371.