Publications:  Prof Atholl Johnston

Green L, Roberts N, Cooper J, Chang I, Gill R, Klein A, Agarwal S, Rossi A et al. (2020). Prothrombin complex concentrate versus fresh frozen plasma in adults undergoing heart surgery (PROPHESY) - a pragmatic pilot randomized controlled trial. BRITISH JOURNAL OF HAEMATOLOGY. vol. 189, 152-153.

Green L, Roberts N, Cooper J, Field J, Gill R, Klein A, Agarwal S, Stanworth S et al.(2019). A pragmatic pilot phase II randomised controlled trial of prothrombin complex concentrates (PCC) versus fresh frozen plasma (FFP) in adult patients who are undergoing heart surgery (PROPHESY). Trials vol. 20, (1) 684-684.

Rahman M, Couchman L, Povstyan V, Bainbridge V, Kipper K, El-Nahhas T, Johnston A, Holt D(2019). Rapid Quantitation of Flecainide in Human Plasma for Therapeutic Drug Monitoring Using Liquid Chromatography and Time-of-Flight Mass Spectrometry. Therapeutic Drug Monitoring vol. 41, (3) 391-395.

Couchman L, Slaughter JA, Coombes G, Johnston A, Ogoti E, Holt DW(2019). The Smell of Death: An Unusual Case of Poisoning with the Organophosphorus Pesticide Chlorfenvinphos. Therapeutic Drug Monitoring vol. 41, (2) 250-252.

Odor PM, Cavalier AG, Reynolds ND, Ang KS, Parrington SJ, Xu H, Johnston A, Sage FJ(2019). Safety and Pharmacokinetics of Levobupivacaine Following Fascia Iliaca Compartment Block in Elderly Patients. Drugs Aging vol. 36, (6) 541-548.

Couchman L, Frinculescu A, Sobreira C, Shine T, Ramsey J, Hecht M, Kipper K, Holt D et al.(2019). Variability in content and dissolution profiles of MDMA tablets collected in the UK between 2001 and 2018 – A potential risk to users?. Drug Testing and Analysis vol. 11, (8) 1172-1182.

JOHNSTON A, Adeloye T, Sahgal O, Puri A, Warrington S, Endo T, Dennison J(2018). Amenamevir: Studies of Potential CYP3A-Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers. Clinical Pharmacology in Drug Development

JOHNSTON A, Hecht M, Veigure R, Couchman L, Barker CIS, Standing J, Takkis K, Evard H et al.(2018). Utilisation of data below the analytical limit of quantitation in pharmacokinetic analysis and modelling: promoting interdisciplinary debate. Bionalysis

Edmonds ME, Bodansky HJ, Boulton AJM, Chadwick PJ, Dang CN, D'Costa R, Johnston A, Kennon B et al.(2018). Multicenter, randomized controlled, observer-blinded study of a nitric oxide generating treatment in foot ulcers of patients with diabetes-ProNOx1 study. Wound Repair Regen vol. 26, (2) 228-237.

Dennison J, Puri A, Warrington S, Endo T, Adeloye T, Johnston A(2018). Amenamevir: Studies of Potential CYP2C8- and CYP2B6-Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers. Clinical Pharmacology in Drug Development

Sawhney V, Brouilette S, Campbell N, Coppen S, Baker V, Hunter R, Dhinoja M, Johnston A et al.(2018). Association of genetic variation in telomere-related SNP and telomerase with ventricular arrhythmias in ischemic cardiomyopathy. PACE - Pacing and Clinical Electrophysiology vol. 41, (3) 261-266.

Kipper K, Barker CIS, Standing JF, Sharland M, Johnston A(2018). Development of a novel multipenicillin assay and assessment of the impact of analyte degradation: Lessons for scavenged sampling in antimicrobial pharmacokinetic study design. Antimicrobial Agents and Chemotherapy vol. 62, (1)

JOHNSTON A(2017). On the use of substandard medicines in hematology: an emerging concern in the Middle East and North Africa region. European Journal of Internal Medicine

Stathopoulou T-R, Kouki M, Pypendop BH, Johnston A, Papadimitriou S, Pelligand L(2017). Evaluation of analgesic effect and absorption of buprenorphine after buccal administration in cats with oral disease. J Feline Med Surg1098612X17727234-1098612X17727234.

JOHNSTON A, Wolff K, Agombar R, Clatworthy A, Cowan D, Forrest R, Osselton D, Scott Ham M (2017). Expert Panel Review of alternative biological matrices for use as an evidential sample for drug driving. The United Kingdom Department for Transport (Online), report no. RM4825 SB-2988,

Fisher DL, Plange-Rhule J, Moreton M, Eastwood JB, Kerry SM, Micah F, Johnston A, Cappuccio FP et al.(2016). CYP3A5 as a candidate gene for hypertension: No support from an unselected indigenous West African population. Journal of Human Hypertension vol. 30, (12) 778-782.

Brixner D, Maniadakis N, Kalo Z, Hu S, Johnston A, Shen J, Wijaya KE (2016). APPLICATION OF MULTI-CRITERIA DECISION ANALYSIS (MCDA) SCORING AS AN HTA METHODOLOGY FOR OFF-PATENT PHARMACEUTICALS (OPP) IN EMERGING MARKETS. vol. 19, is. 7, pp. A815-A815.

Sawhney V, Campbell NG, Brouilette SW, Coppen SR, Harbo M, Baker V, Ikebe C, Shintani Y et al.(2016). Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients - Potential markers of ventricular arrhythmia. International Journal of Cardiology vol. 207, 157-163.

De Palma R, Sotto I, Wood EG, Khan NQ, Butler J, Johnston A, Rothman MT, Corder R(2015). Cocoa flavanols reduce N-terminal pro-B-type natriuretic peptide in patients with chronic heart failure. ESC Heart Fail vol. 3, (2) 97-106.

El-Nahhas T, Moreton M, Popoola J, Abat S, Johnston A, MacPhee I (2015). Conversion from Immediate to Prolonged Release Tacrolimus Did Not Change Intra-Patient Variability in Renal Transplant Patients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 15,

Elnahhas T, Lee T, Moreton M, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2015). Influence of CYP3A5 and ABCB1 Genotypes on Pharmacokinetics of Immediate and Prolonged Release Tacrolimus Preparations. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 15,

Elnahhas T, de Jonge E, Lee T, van Zelst B, Popoola J, Ramkhelawon R, van Schaik R, Johnston A et al. (2015). Plasma 4 beta-Hydroxycholesterol Measurement as a Potential Biomarker for CYP3A5 Activity in Informing Tacrolimus Dosing. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 15,

Rull G, Mohd-Zain Z, Shiel J, Lundberg MH, Collier DJ, Johnston A, Warner TD, Corder R(2015). Effects of High Flavanol Dark Chocolate on Cardiovascular Function and Platelet Aggregation. Vascular pharmacology

Johnston A, Holt DW(2014). Substandard drugs: a potential crisis for public health. Br J Clin Pharmacol vol. 78, (2) 218-243.

Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). CYP3A5/ABCB1 Combined Genotype Has Similar Influence On Pharmacokinetics of Immediate and Prolonged Release Tacrolimus in Renal Transplant Recipients. TRANSPLANTATION. vol. 98, 548-548.

Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). Impact of CYP3A5 and ABCB1 Genotype On The Pharmacokinetics of Prednisolone in Renal Transplant Recipients. TRANSPLANTATION. vol. 98, 548-549.

Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). CYP3A5/ABCB1 Combined Genotype Has Similar Influence On Pharmacokinetics of Immediate and Prolonged Release Tacrolimus in Renal Transplant Recipients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 14, 548-548.

Al-Otaibi F, Ghazaly E, Johnston A, Perrett D(2014). Development of HPLC-UV method for rapid and sensitive analysis of topically applied tetracaine: its comparison with a CZE method. Biomed Chromatogr vol. 28, (6) 826-830.

Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). Impact of CYP3A5 and ABCB1 Genotype On The Pharmacokinetics of Prednisolone in Renal Transplant Recipients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 14, 548-549.

Payne-James JJ, Rivers E, Green P, Johnston A(2014). Trends in less-lethal use of force techniques by police services within England and Wales: 2007-2011. Forensic Sci Med Pathol vol. 10, (1) 50-55.

Wolff K, Johnston A(2014). Cannabis use: a perspective in relation to the proposed UK drug-driving legislation. DRUG TESTING AND ANALYSIS vol. 6, (1-2) 143-154.

Archer JRH, Dargan PI, Hudson S, Davies S, Puchnarewicz M, Kicman AT, Ramsey J, Measham F et al.(2014). Taking the Pissoir - a novel and reliable way of knowing what drugs are being used in nightclubs. JOURNAL OF SUBSTANCE USE vol. 19, (1-2) 103-107.

Jawad H, Bain DS, Dawson H, Crawford K, Johnston A, Tucker A(2014). The effectiveness of a novel neuromuscular electrostimulation method versus intermittent pneumatic compression in enhancing lower limb blood flow. Journal of Vascular Surgery: Venous and Lymphatic Disorders vol. 2, (2) 160-165.

Lane K, Dixon JJ, McKeown D, Johnston A, Van Schaik RHN, Van Fessem M, MacPhee IAM, Philips BJ(2014). Using tramadol to measure CYP2D6 metabolism in critically ill adults. Intensive Care Medicine vol. 40, (8) 1177-1178.

Johnston A(2013). Equivalence and interchangeability of narrow therapeutic index drugs in organ transplantation. EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE vol. 20, (5) 302-307.

Al Ameri M, Tucker A, Johnston A(2013). ECONOMIC EVALUATION OF USING BRANDED TAXOTERE (R) VERSUS. GENERIC DOCETAXEL: BASED ON DECISION TREE MODEL. VALUE IN HEALTH vol. 16, (3) A187-A187.

Al Ameri MN, Mohamed W, Makramalla E, Shalhoub B, Tucker A, Johnston A(2013). Renal patients' views on generic prescribing and substitution: example from the United Arab Emirates. EASTERN MEDITERRANEAN HEALTH JOURNAL vol. 19, (4) 373-381.

Dargan PI, Davies S, Puchnarewicz M, Johnston A, Wood DM(2013). First reported case in the UK of acute prolonged neuropsychiatric toxicity associated with analytically confirmed recreational use of phenazepam. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY vol. 69, (3) 361-363.

Poulton PR, Johnston AE, White RP(2013). Plant-available soil phosphorus. Part I: The response of winter wheat and spring barley to Olsen P on a silty clay loam. Soil Use and Management vol. 29, (1) 4-11.

Johnston AE, Poulton PR, White RP(2013). Plant-available soil phosphorus. Part II: The response of arable crops to Olsen P on a sandy clay loam and a silty clay loam. Soil Use and Management vol. 29, (1) 12-21.

Handley R, Zelaya FO, Reinders AATS, Marques TR, Mehta MA, O'Gorman R, Alsop DC, Taylor H et al.(2013). Acute effects of single-dose aripiprazole and haloperidol on resting cerebral blood flow (rCBF) in the human brain. HUMAN BRAIN MAPPING vol. 34, (2) 272-282.

de Palma R, Sotto I, Khan NQ, Wood EG, Butler J, Johnston A, Rothman MT, Corder R(2012). High Flavanol Dark Chocolate Reduces NT-proBNP in Patients with Chronic Heart Failure. CIRCULATION vol. 126, (21)

Al Ameri MN, Tucker A, Johnston A(2012). ECONOMIC EVALUATION OF USING BRANDED TAXOTERE (R) VERSUS GENERIC DOCETAXEL: BASED ON DECISION TREE MODEL. VALUE IN HEALTH vol. 15, (7) A416-A417.

White PJ, Broadley MR, Thompson JA, McNicol JW, Crawley MJ, Poulton PR, Johnston AE(2012). Testing the distinctness of shoot ionomes of angiosperm families using the rothamsted park grass continuous hay experiment. New Phytologist vol. 196, (1) 101-109.

Boyce M, David O, Darwin K, Mitchell T, Johnston A, Warrington S(2012). Single oral doses of netazepide (YF476), a gastrin receptor antagonist, cause dose-dependent, sustained increases in gastric pH compared with placebo and ranitidine in healthy subjects. Alimentary Pharmacology and Therapeutics vol. 36, (2) 181-189.

Aljohani B, Al Otaibi F, Ghazaly E, Perrett D, Johnston A (2012). Development and validation of a h.p.l.c. method for ciclosporin: its application to measurement of brand and generic versions from different countries. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 1007-1007.

Al Ameri MN, Nayuni N, Kumar A, Perrett D, Tucker A, Johnston A (2012). Differences between the branded and generic solid dosage form medicines: in vitro dissolution testing. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 984-984.

Mendis SVG, Perrett D, Johnston A (2012). Factors influencing ethanol elimination in 20 to 30-year-old European males. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 987-988.

Johnston A, Schick L, van Gelder T(2012). Integrating narrow therapeutic index drug formulations in transplantation. EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE vol. 19, (3) 318-319.

Sathiyayogan N, Watts J, Ravi N, Johnston A (2012). NHS R&D offices - Research and Development or Retard and Delay?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 988-988.

Al Ameri MN, Whittaker C, Mohamed W, Makramalla E, Shalhoub B, Yaqoob M, Tucker A, Johnston A (2012). Patients' views on generic substitution in the United Arab Emirates (UAE): focus on renal patients. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 994-994.

Wood DM, Davies S, Puchnarewicz M, Johnston A, Dargan PI(2012). Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY vol. 68, (5) 853-856.

Wood DM, Puchnarewicz M, Johnston A, Dargan PI(2012). A case series of individuals with analytically confirmed acute diphenyl-2-pyrrolidinemethanol (D2PM) toxicity. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY vol. 68, (4) 349-353.

Baker TM, Goh J, Johnston A, Falvey H, Brede Y, Brown RE(2012). Cost-effectiveness analysis of valsartan versus losartan and the effect of switching. Journal of Medical Economics vol. 15, (2) 253-260.

Dargan PI, Davies S, Puchnarewicz M, Johnston A, Wood DM(2012). First Reported Case of Acute Prolonged Neuropsychiatric Toxicity Associated With Analytically Confirmed Recreational Use of Phenazepam. CLINICAL TOXICOLOGY vol. 50, (4) 324-324.

Wood DM, Davies S, Puchnarewicz M, Johnston A, Dargan PI(2012). Methoxetamine: A Ketamine Analogue Associated with Both Ketamine-like Dissociative Effects and Sympathomimetic Toxicity. CLINICAL TOXICOLOGY vol. 50, (4) 342-342.

Kassim S, Hawash A, Johnston A, Croucher R(2012). Validation of self-reported khat chewing amongst khat chewers: an exploratory study. J Ethnopharmacol vol. 140, (1) 193-196.

Murray DB, Potts S, Haxton C, Jackson G, Sandilands EA, Ramsey J, Puchnarewicz M, Holt DW et al.(2012). 'Ivory wave' toxicity in recreational drug users; Integration of clinical and poisons information services to manage legal high poisoning. Clinical Toxicology vol. 50, (2) 108-113.

Johnston A(2012). The relevance of factor VIII (FVIII) pharmacokinetics to TDM and hemophilia a treatment: is B domain-deleted FVIII equivalent to full-length FVIII?. Ther Drug Monit vol. 34, (1) 110-117.

Ameri MNA, Nayuni N, Anil Kumar KG, Perrett D, Tucker A, Johnston A(2012). The differences between the branded and generic medicines using solid dosage forms: In-vitro dissolution testing. Results in Pharma Sciences vol. 2, (1) 1-8.

Al Ameri MN, Epstein M, Johnston A(2011). Generic and therapeutic substitution: a response to our critic. Int J Clin Pharm vol. 33, (6)

Levine DM, Maine GT, Armbruster DA, Mussell C, Buchholz C, O'Connor G, Tuck V, Johnston A et al.(2011). The need for standardization of tacrolimus assays. Clinical Chemistry vol. 57, (12) 1739-1747.

Johnston A, Asmar R, Dahlöf B, Hill K, Jones DA, Jordan J, Livingston M, Macgregor G et al.(2011). Generic and therapeutic substitution: a viewpoint on achieving best practice in Europe. Br J Clin Pharmacol vol. 72, (5) 727-730.

Al Ameri MN, Whittaker C, Tucker A, Yaqoob M, Johnston A(2011). A survey to determine the views of renal transplant patients on generic substitution in the UK. Transpl Int vol. 24, (8) 770-779.

Grossman SE, Johnston A, Vanezis P, Perrett D(2011). Can we assess the age of bruises? An attempt to develop an objective technique. Med Sci Law vol. 51, (3) 170-176.

Moore J, He X, Shabir S, HanvesakulPhd R, Benavente D, Cockwell P, Little MA, Ball S et al.(2011). Development and Evaluation of a Composite Risk Score to Predict Kidney Transplant Failure. AM J KIDNEY DIS vol. 57, (5) 744-751.

Chew AL, Bashir SJ, Johnston A, Barker JNWN, Smith CH(2011). The value of monitoring ciclosporin concentration 2 hours post-dose (C2) in dermatology: A prospective cohort study. J DERMATOL TREAT vol. 22, (2) 79-85.

Moore J, He XA, Liu XA, Shabir S, Ball S, Cockwell P, Inston N, Little MA et al.(2011). Mortality Prediction After Kidney Transplantation: Comparative Clinical Use of 7 Comorbidity Indices. EXP CLIN TRANSPLANT vol. 9, (1) 32-41.

Chik Z, Tucker AT, Shiel JI, Collier DJ, Perrett D, Lee TD, Johnston A(2010). Comparative Pharmacokinetic Assessments of Topical Drugs: Evaluation by Dermatopharmacokinetics, Microdialysis, and Systemic Measurement. J INVEST DERMATOL vol. 130, (12) 2828-2830.

AlAmeri M, Epstein M, Johnston A(2010). Generic and therapeutic substitutions: are they always ethical in their own terms?. Pharm World Sci vol. 32, (6) 691-695.

Couchman L, Morgan PE, Spencer EP, Johnston A, Flanagan RJ(2010). Plasma clozapine and norclozapine in patients prescribed different brands of clozapine (Clozaril, Denzapine, and Zaponex). Ther Drug Monit vol. 32, (5) 624-627.

Johnston A, Stafylas P, Stergiou GS(2010). Effectiveness, safety and cost of drug substitution in hypertension. Br J Clin Pharmacol vol. 70, (3) 320-334.

Wood D, Panayi P, Davies S, Collignon U, Button J, Ramsey J, Johnston A, Holt D et al. (2010). Analysis of recreational drug samples obtained from/left by patients presenting to a busy inner-city Emergency Department. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 70, 289-290.

Powlson DS, Jenkinson DS, Johnston AE, Poulton PR, Glendining MJ, Goulding KWT(2010). Reply to additional comments on "Synthetic nitrogen fertilizers deplete soil nitrogen: A global dilemma for sustainable cereal production," by R.L. Mulvaney, S.A. Khan, and T.R. Ellsworth in the Journal of Environmental Quality 2009 38:2295-2314. Journal of Environmental Quality vol. 39, (4) 1528-1529.

Johnston A(2010). Challenges of therapeutic substitution of drugs for economic reasons: focus on CVD prevention. Curr Med Res Opin vol. 26, (4) 871-878.

Al Ameri M, Johnston A, Epstein M(2010). Ethical issues in generic and therapeutic substitution. PHARM WORLD SCI vol. 32, (2) 269-269.

Pilling ML, Vanezis P, Perrett D, Johnston A(2010). Visual assessment of the timing of bruising by forensic experts. J Forensic Leg Med vol. 17, (3) 143-149.

Powlson DS, Jenkinson DS, Johnston AE, Poulton PR, Glendining MJ, Goulding KWT(2010). Comments on "Synthetic nitrogen fertilizers deplete soil nitrogen: A global dilemma for sustainable cereal production," by R.L. Mulvaney, S.A. Khan, and T.R. Ellsworth in the Journal of Environmental Quality 2009 38:2295-2314. Journal of Environmental Quality vol. 39, (2) 749-752.

Tucker A, Maass A, Bain D, Chen L-H, Azzam M, Dawson H, Johnston A(2010). Augmentation of venous, arterial and microvascular blood supply in the leg by isometric neuromuscular stimulation via the peroneal nerve. Int J Angiol vol. 19, (1) e31-e37.

EPSTEIN AM, Al Ameri MN, Johnston A (2009). Ethical issues in generic and therapeutic substitution. Presented at: William Harvey Research Institute, Barts and The London School of Medicine and Dentistry,

Al-Otaibi F, Ghazaly EA, Tucker AT, Johnston A, Perrett D (2009). Development of High Performance Liquid Chromatograph Method for Analysis of Tetracaine for a Tape Stripping Pharmacokinetic Study: A Comparison with Capillary Zone Electrophoresis (CE). THERAPEUTIC DRUG MONITORING. vol. 31, 656-656.

Al-Otaibi F, Tucker AT, Johnston A, Perrett D (2009). Rapid Analysis of Tetracaine for a Tape Stripping Pharmacokinetic Study Using Short-end Capillary Electrophoresis. THERAPEUTIC DRUG MONITORING. vol. 31, 655-655.

Al-Otaibi F, Johnston A, Tucker AT, Lee T, Langford R, Ratcliffe S, Kirby K, Alam C (2009). Systemic Measurement of TDS (R)-Diazepam, Compared with Rectal Diazepam, a Pharmacokinetic Study in Healthy Adult Subjects. THERAPEUTIC DRUG MONITORING. vol. 31, 655-655.

Jones AE, Wilson HK, Meath P, Meng XL, Holt DW, Johnston A, Oellerich M, Armstrong VW et al.(2009). Convenient syntheses of the in vivo carbohydrate metabolites of mycophenolic acid: reactivity of the acyl glucuronide. TETRAHEDRON LETT vol. 50, (35) 4973-4977.

Al-Otaibi F, Tucker A, Johnston A, Perrett D (2009). Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 68, 299-300.

Jorns TP, Johnston A, Zakrzewska JM(2009). Pilot study to evaluate the efficacy and tolerability of levetiracetam (Keppra((R))) in treatment of patients with trigeminal neuralgia. EUR J NEUROL vol. 16, (6) 740-744.

Payne-James JJ, Anderson WR, Green PG, Johnston A(2009). Provision of forensic medical services to police custody suites in England and Wales: current practice. J Forensic Leg Med vol. 16, (4) 189-195.

Al-Otaibi F, Tucker AT, Johnston A, Perrett D(2009). Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis. Biomed Chromatogr vol. 23, (5) 488-491.

Chik Z, Johnston A, Tucker AT, Kirby K, Alam CA(2009). Correcting endogenous concentrations of testosterone influences bioequivalence and shows the superiority of TDS (R)-testosterone versus Androgel (R). INT J CLIN PHARM TH vol. 47, (4) 262-268.

Wallemacq P, Armstrong VW, Brunet M, Haufroid V, Holt DW, Johnston A, Kuypers D, Le Meur Y et al.(2009). Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. Ther Drug Monit vol. 31, (2) 139-152.

Johnston AE, Poulton PR, Coleman K(2009). Chapter 1 Soil Organic Matter. Its Importance in Sustainable Agriculture and Carbon Dioxide Fluxes. Advances in Agronomy vol. 101, 1-57.

He X, Moore J, Shabir S, Little MA, Cockwell P, Ball S, Liu X, Johnston A et al.(2009). Comparison of the Predictive Performance of eGFR Formulae for Mortality and Graft Failure in Renal Transplant Recipients. TRANSPLANTATION vol. 87, (3) 384-392.

He X, Moore J, Liu X, Shabir S, Cockwell P, Little MA, Ball S, Inston N et al. (2009). A Simple "Kidney Risk Score" (KRS) and "Mortality Risk Score" (MRS) for Renal Transplant Recipients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 9, 428-428.

Moore J, Liu X, He X, Shabir S, Ball S, Cockwell P, Inston N, Little MA et al. (2009). Impact of Comorbidity on Mortality Following Renal Transplantation: Comparative Clinical Utility of Seven Scoring Systems. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 9, 593-593.

Moore J, He X, Cockwell P, Little MA, Johnston A, Borrows R(2008). The impact of hemoglobin levels on patient and graft survival in renal transplant recipients. TRANSPLANTATION vol. 86, (4) 564-570.

Al-Otaibi F, Johnston A, Tucker A, Lee T, Langford R, Ratcliffe S, Alam C (2008). A randomized, single-dose, two-period, cross-over pharmacokinetic study to compare TDS (R)-diazepam with rectal diazepam in healthy adult subjects. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 65, 1002-1002.

He X, MacPhee I, Johnston A (2008). Cardiovascular risk factors and their management in renal transplant recipients. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 65, 998-999.

Ghazaly E, Joel S, Johnston A (2008). Etoposide catechol, is it an important metabolite?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 65, 984-985.

Mehta V, Johnston A, Cheung R, Bello A, Langford RM(2008). Intravenous parecoxib rapidly leads to COX-2 inhibitory concentration of valdecoxib in the central nervous system. Clin Pharmacol Ther vol. 83, (3) 430-435.

Cattran DC, Alexopoulos E, Heering P, Hoyer PF, Johnston A, Meyrier A, Ponticelli C, Saito T et al.(2007). Cyclosporin in idiopathic glomerular disease associated with the nephrotic syndrome : Workshop recommendations. KIDNEY INT vol. 72, (12) 1429-1447.

Galanello R, Forni G, Jones A, Kelly A, Willemsen A, He X, Johnston A, Fuller D et al. (2007). A dose escalation study of the pharmacokinetics, safety & efficacy of deferitrin an oral iron chelator in beta thalassaemia patients. BLOOD. vol. 110, 784A-785A.

Marlowe SNS, Leekassa R, Bizuneh E, Knuutilla J, Ale P, Bhattarai B, Sigdel H, Anderson A et al.(2007). Response to ciclosporin treatment in Ethiopian and Nepali patients with severe leprosy Type 1 reactions. Transactions of the Royal Society of Tropical Medicine and Hygiene vol. 101, (10) 1004-1012.

He X, Holt DW, Johnston A(2007). An algorithm to predict individual MPA AUC for de novo renal transplant patients receiving EC-MPS. TRANSPL INT vol. 20, 115-115.

He X, Holt DW, Johnston A (2007). Predicting MPA AUC for de novo renal transplant patients receiving EC-MPS. THERAPEUTIC DRUG MONITORING. vol. 29, 473-473.

Chik Z, Johnston A, Tucker AT, Burn RT, Perrett D(2007). Validation and application of capillary electrophoresis for the analysis of lidocaine in a skin tape stripping study. BIOMED CHROMATOGR vol. 21, (8) 775-779.

Ravic N, Tucker AT, Wareham DW, Johnston A, Hinds CJ (2007). A study of novel oxides of nitrogen generating solution to prevent microbial colonization and ventilator associated pneumonia (VAP). BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 781-781.

Chik Z, Tucker AT, Shiel JI, Collier DJ, Perrett D, Lee TD, Johnston A (2007). Comparative pharmacokinetic assessments of topically applied drugs: evaluation by dermatopharmacokinetic, microdialysis and systemic measurement. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 775-776.

Collier D, Arunachalam G, Johnston A, Richards S, Shiel J, Wells Z, David C, Caulfield M (2007). Continuing reduction of microalbuminuria and proteinuria during follow-up for the Anglo-Scandinavian Cardiac Outcomes Trial dominance of duration and blood pressure over other effects. JOURNAL OF HYPERTENSION. vol. 25, S150-S150.

Tucker AT, Barnes NC, Johnston A, Elston WJ, Watson D, Wilks M, Rahman R, Rehman I (2007). Formulation and validation of a novel solution of nitric oxide for delivery to the respiratory tract. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 781-781.

El-Safa EA, Fredericks S, MacPhee I, Johnston A, Holt DW (2007). Interindividual variation in response to tacrolimus assessed by IL-2 gene expression in renal transplant patients. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 789-790.

Jorns TP, Johnston A, Zakrzewska JM (2007). Pilot study to evaluate the efficacy and tolerability of levetiracetam in the treatment of patients with trigeminal neuralgia. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 785-786.

Ghazaly EA, Johnston A, Joel SP (2007). Simultaneous determination of 6 beta-hydroxycortisol and cortisol in human urine by high performance liquid chromatography using ultraviolet detector for CYP3A4 phenotyping. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 790-790.

Fredericks S, Jorga A, MacPhee IAM, Reboux S, Shiferaw E, Moreton M, Carter ND, Holt DW et al.(2007). Multi-drug resistance gene-1 (MDR-1) haplotypes and the CYP3A5*1 genotype have no influence on ciclosporin dose requirements as assessed by C0 or C2 measurements. CLIN TRANSPLANT vol. 21, (2) 252-257.

Brown KM, Kondeatis E, Vaughan RW, Kon SP, Farmer CKT, Taylor JD, He X, Johnston A et al. (2007). Influence of donor C3 allotype on late renal transplantation outcome. MOLECULAR IMMUNOLOGY. vol. 44, 157-158.

Johnston A, He X, Holt DW(2006). Bioequivalence of enteric-coated mycophenolate sodium and mycophenolate mofetil: a meta-analysis of three studies in stable renal transplant recipients. Transplantation vol. 82, (11) 1413-1418.

El-Safa EA, Fredericks S, MacPhee I, Holt DW, Johnston A (2006). Paradoxical response to tacrolimus assessed by interleukin-2 gene expression. Transplant Proc. vol. 38, 3327-3330.

Hassanin A, Lee RGM, Johnston AE, Jones KC(2006). Reductions and changing patterns of ambient PCDD/Fs in the UK: Evidence and implications. Chemosphere vol. 65, (3) 530-539.

Griffiths CEM, Katsambas A, Dijkmans BAC, Finlay AY, Ho VC, Johnston A, Luger TA, Mrowietz U et al. (2006). Update on the use of ciclosporin in immune-mediated dermatoses. BRITISH JOURNAL OF DERMATOLOGY. vol. 155, 1-16.

Brown KM, Kondeatis E, Vaughan RW, Kon SP, Farmer CKT, Taylor JD, He X, Johnston A et al.(2006). Influence of donor C3 allotype on late renal-transplantation outcome. NEW ENGL J MED vol. 354, (19) 2014-2023.

Chik Z, Lee TD, Holt DW, Johnston A, Tucker AT(2006). Validation of high-performance liquid chromatographic-mass spectrometric method for the analysis of lidocaine in human plasma. J Chromatogr Sci vol. 44, (5) 262-265.

Dooldeniya MD, Dupont PJ, He X, Johnson RJ, Joshi T, Basra R, Johnston A, Warrens AN(2006). Renal transplantation in indo-asian patients in the UK. AM J TRANSPLANT vol. 6, (4) 761-769.

Chik Z, Johnston A, Tucker AT, Chew SL, Michaels L, Alam CAS(2006). Pharmacokinetics of a new testosterone transdermal delivery system, TDS-testosterone in healthy males. Br J Clin Pharmacol vol. 61, (3) 275-279.

Tucker AT, Chik Z, Michaels L, Kirby K, Seed MP, Johnston A, Alam CAS(2006). Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture. Anaesthesia vol. 61, (2) 123-126.

Kenyon SL, Ramsey JD, Lee T, Johnston A, Holt DW(2005). Analysis for identification in amnesty bin samples from dance venues. THER DRUG MONIT vol. 27, (6) 793-798.

Scott BF, Spencer C, Martin JW, Barra R, Bootsma HA, Jones KC, Johnston AE, Muir DCG(2005). Comparison of haloacetic acids in the environment of the Northern and Southern Hemispheres. Environmental Science and Technology vol. 39, (22) 8664-8670.

Moreton M, Fredericks S, McKeown DA, Shiferaw EW, MacPhee LAM, Johnston A, Holt DW(2005). CYP3A5 genotype does not influence the blood concentration of tacrolimus measured with the Abbott immunoassay. CLIN CHEM vol. 51, (11) 2214-2215.

Rocks SA, Davies CA, Hicks SL, Webb AJ, Klocke R, Timmins GS, Johnston A, Jawad ASM et al.(2005). Measurement of S-nitrosothiols in extracellular fluids from healthy human volunteers and rheumatoid arthritis patients, using electron paramagnetic resonance spectrometry. Free Radic Biol Med vol. 39, (7) 937-948.

Turner M, McCrory P, Johnston A(2005). Time for tea, anyone?. BRIT J SPORT MED vol. 39, (10) Article e37,

Fredericks S, Moreton M, MacPhee IAM, Mohamed M, Marlowe S, Jorga AM, Johnston A, Carter ND et al.(2005). Genotyping cytochrome P450 3A5 using the light cycler. ANN CLIN BIOCHEM vol. 42, 376-381.

Chew AL, Johnston A, Barker JNWN, Smith CH (2005). The value of ciclosporin C2 monitoring in dermatology: a pilot study. BRITISH JOURNAL OF DERMATOLOGY. vol. 153, 39-39.

Nashan B, Bock A, Bosmans JL, Budde K, de Fijter H, Jaques B, Johnston A, Luck R et al.(2005). Use of neoral C-2 monitoring: a European consensus. TRANSPL INT vol. 18, (7) 768-778.

Perrie JA, Harding JR, Holt DW, Johnston A, Meath P, Stachulski AV(2005). Effective synthesis of 1,beta-acyl glucuronides by selective acylation. ORG LETT vol. 7, (13) 2591-2594.

Chik Z, Johnston A, Tucker AT, Chew SL, Alam CAS(2005). Pharmacokinetic study of the transdermal delivery system, TDS (c)-testosterone in healthy subjects. BRIT J CLIN PHARMACO vol. 59, (5) 636-636.

He X, Johnston A(2005). Risk factors for allograft failure in United kingdom renal transplant recipients treated with cyclosporine A. Transplantation vol. 79, (8) 953-957.

Hassanin A, Johnston AE, Thomas GO, Jones KC(2005). Time trends of atmospheric PBDEs inferred from archived U.K. herbage. Environmental Science and Technology vol. 39, (8) 2436-2441.

Jorga A, Johnston A(2005). Novel therapies in transplantation. Expert Opin Investig Drugs vol. 14, (3) 295-304.

MacPhee IAM, Fredericks S, Mohamed M, Moreton M, Carter ND, Johnston A, Goldberg L, Holt DW(2005). Tacrolimus pharmacogenetics: The CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and south Asians. TRANSPLANTATION vol. 79, (4) 499-502.

Crawley MJ, Johnston AE, Silvertown J, Dodd M, De Mazancourt C, Heard MS, Henman DF, Edwards GR(2005). Determinants of species richness in the park grass experiment. American Naturalist vol. 165, (2) 179-192.

Buchler M, Johnston A (2005). Seeking optimal prescription of cyclosporine ME. THERAPEUTIC DRUG MONITORING. vol. 27, 3-6.

Holt DW, Moreton M, Laamanen K, Johnston A (2005). A microparticle enzyme immunoassay to measure sirolimus. TRANSPLANTATION PROCEEDINGS. vol. 37, 182-184.

Wolff CB, Checkley SK, Bhageerutty G, Bhatt H, Johnston A, Collier DJ, Tachtsidis I, Garvie N et al. (2005). Circulation time in man from lung to periphery as an indirect index of cardiac output. Adv Exp Med Biol. vol. 566, 311-316.

Stewart WM, Dibb DW, Johnston AE, Smyth TJ(2005). The contribution of commercial fertilizer nutrients to food production. Agronomy Journal vol. 97, (1) 1-6.

Rocks S, Davies C, Hicks S, Webb A, Klocke R, Timmins G, Johnston A, Jawad A et al. (2005). Validation and clinical applications of a new EPR assay for plasma S-nitrosothiols. FREE RADICAL BIOLOGY AND MEDICINE. vol. 39, S56-S56.

Jorga A, Holt DW, Yaqoob M, Whittaker C, Johnston A(2004). A survey to determine the blood concentration of cyclosporine 2 hours postdose in stable renal transplant patients. Transplant Proc vol. 36, (10) 3239-3241.

He X, Johnston A(2004). Early acute rejection does not affect chronic allograft nephropathy and death censored graft failure. Transplant Proc vol. 36, (10) 2993-2996.

Holt DW, McKeown DA, Lee TD, Hicks D, Cal P, Johnston A(2004). The relative proportions of sirolimus metabolites in blood using HPLC with mass-spectrometric detection. Transplant Proc vol. 36, (10) 3223-3225.

Ravic M, Warrington S, Boyce M, Dunn K, Johnston A(2004). Repeated dosing with donepezil does not affect the safety, tolerability or pharmacokinetics of single-dose thioridazine in young volunteers. Br J Clin Pharmacol vol. 58 Suppl 1, 34-40.

Zacharowski P, Zacharowski K, Donnellan C, Johnston A, Vojnovic I, Forte P, Del Soldato P, Benjamin N et al.(2004). The effects and metabolic fate of nitroflurbiprofen in healthy volunteers. Clin Pharmacol Ther vol. 76, (4) 350-358.

Johnston A, Belitsky P, Frei U, Horvath J, Hoyer P, Helderman JH, Oellerich M, Pollard S et al.(2004). Potential clinical implications of substitution of generic cyclosporine formulations for cyclosporine microemulsion (Neoral) in transplant recipients. Eur J Clin Pharmacol vol. 60, (6) 389-395.

Holt DW, Johnston A(2004). Monitoring immunosuppressive drugs - Has it a future?. THER DRUG MONIT vol. 26, (3) 244-247.

MacPhee IAM, Fredericks S, Tai T, Syrris P, Carter ND, Johnston A, Goldberg L, Holt DW(2004). The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation. AM J TRANSPLANT vol. 4, (6) 914-919.

He X, Johnston A(2004). Variable cyclosporine exposure: a risk factor for chronic allograft nephropathy and graft loss?. Transplant Proc vol. 36, (5) 1321-1326.

Griffiths CEM, Dubertret L, Ellis CN, Finlay AY, Finzi AF, Ho VC, Johnston A, Katsambas A et al.(2004). Ciclosporin in psoriasis clinical practice: an international consensus statement. BRIT J DERMATOL vol. 150, 11-23.

Jenkinson DS, Poulton PR, Johnston AE, Powlson DS(2004). Turnover of nitrogen-15-labeled fertilizer in old grassland. Soil Science Society of America Journal vol. 68, (3) 865-875.

Jorga A, Holt DW, Johnston A(2004). Therapeutic drug monitoring of cyclosporine. Transplant Proc vol. 36, (2 Suppl) 396S-403S.

Green NJL, Hassanin A, Johnston AE, Jones KC(2004). Observations on Historical, Contemporary, and Natural PCDD/Fs. Environmental Science and Technology vol. 38, (3) 715-723.

Jorga A, Johnston A, Holt DW(2004). Patient management by cyclosporine C2 monitoring. TRANSPLANTATION vol. 77, (2) 323-324.

Holt DW, Johnston A(2004). Chapter 11 monitoring immunosuppressive drugs. vol. 5, 273-296.

Wilson S, Johnston A, Robson J, Murchie P, Mann DM, Natarajan S(2004). Cholesterol screening in people aged > 50 years effectively identifies people at high risk of coronary disease. Evidence-Based Healthcare vol. 8, (1) 15-17.

Johnston AJ, Steiner LA, O'Connell M, Chatfield DA, Gupta AK, Menon DK(2004). Pharmacokinetics and pharmacodynamics of dopamine and norepinephrine in critically ill head-injured patients. Intensive Care Med vol. 30, (1) 45-50.

He X, Johnston A (2004). Pre-transplant risk factors for UK renal transplant patient with ciclosporin. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 4, 489-489.

DiDomenico RJ, Eyrich HM, Baker CSR, Johnston A, Baker LRI, Knight CJ(2003). Did Contrast Nephropathy in RAPPID Really Occur? [1] (multiple letters). Journal of the American College of Cardiology vol. 42, (12) 2167-2169.

Huxtable L, Raney CRK, Khera GS, Baker CSR, Johnston A, Baker LRI, Knight CJ(2003). Should Intravenous n-Acetylcysteine Be Considered Standard of Care for Prevention of Radio-Contrast-Induced Nephropathy? [2] (multiple letters). Journal of the American College of Cardiology vol. 42, (12) 2169-2170.

Johnston AJ, Steiner LA, Chatfield DA, Coleman MR, Coles JP, Al-Rawi PG, Menon DK, Gupta AK(2003). Effects of propofol on cerebral oxygenation and metabolism after head injury. Br J Anaesth vol. 91, (6) 781-786.

Johnston A(2003). The pharmacokinetics of voriconazole. Br J Clin Pharmacol vol. 56 Suppl 1,

Clarke A, Johnson ES, Mallard N, Corn TH, Johnston A, Boyce M, Warrington S, MacMahon DG(2003). A new low-dose formulation of selegiline: clinical efficacy, patient preference and selectivity for MAO-B inhibition. J NEURAL TRANSM vol. 110, (11) 1257-1271.

Steiner LA, Coles JP, Johnston AJ, Czosnyka M, Fryer TD, Smielewski P, Chatfield DA, Salvador R et al.(2003). Responses of posttraumatic pericontusional cerebral blood flow and blood volume to an increase in cerebral perfusion pressure. J Cereb Blood Flow Metab vol. 23, (11) 1371-1377.

Steiner LA, Coles JP, Johnston AJ, Chatfield DA, Smielewski P, Fryer TD, Aigbirhio FI, Clark JC et al.(2003). Assessment of cerebrovascular autoregulation in head-injured patients: a validation study. Stroke vol. 34, (10) 2404-2409.

Charmandari E, Pincus SM, Matthews DR, Johnston A, Brook CGD, Hindmarsh PC(2003). Sexual dimorphism in the synchrony of joint growth hormone and cortisol dynamics in children with classic 21-hydroxylase deficiency. J PEDIATR ENDOCR MET vol. 16, (8) 1119-1130.

Wilson S, Johnston A, Robson J(2003). Methods to identify increased risk of coronary disease in the general population - Conclusion is oversimplification - Authors' reply. BRIT MED J vol. 327, (7415) 619-619.

He S, Johnston A (2003). Fluctuating ciclosporin exposure - A risk factor for graft loss?. THERAPEUTIC DRUG MONITORING. vol. 25, 511-511.

Trompeter R, Fitzpatrick M, Hutchinson C, Johnston A(2003). Longitudinal evaluation of the pharmacokinetics of cyclosporin microemulsion (Neoral((R))) in pediatric renal transplant recipients and assessment of C-2 level as a marker for absorption. PEDIATR TRANSPLANT vol. 7, (4) 282-288.

Steiner LA, Johnston AJ, Chatfield DA, Czosnyka M, Coleman MR, Coles JP, Gupta AK, Pickard JD et al.(2003). The effects of large-dose propofol on cerebrovascular pressure autoregulation in head-injured patients. Anesth Analg vol. 97, (2) 572-576.

Blake L, Johnston AE, Poulton PR, Goulding KWT(2003). Changes in soil phosphorus fractions following positive and negative phosphorus balances for long periods. Plant and Soil vol. 254, (2) 245-261.

Wilson S, Johnston A, Robson J, Poulter N, Collier D, Feder G, Caulfield MJ(2003). Comparison of methods to identify individuals at increased risk of coronary disease from the general population. BMJ vol. 326, (7404)

Pollard S, Nashan B, Johnston A, Hoyer P, Belitsky P, Keown P, Helderman H(2003). A pharmacokinetic and clinical review of the potential clinical impact of using different formulations of cyclosporin A. CLIN THER vol. 25, (6) 1654-1669.

Johnston A, Ramsey J(2003). Re: Drugs, driving and sobriety tests. J Clin Forensic Med vol. 10, (2) 126-127.

Johnston AE, Richards IR(2003). Effectiveness of the water-insoluble component of triple superphosphate for yield and phosphorus uptake by plants. Journal of Agricultural Science vol. 140, (3) 267-274.

Holt DW, Denny K, Lee TD, Johnston A(2003). Therapeutic monitoring of sirolimus: Its contribution to optimal prescription. TRANSPLANT P vol. 35, (3A) 157S-161S.

Jorga A, Collier D, Priston B, Clavel D, Johnston A (2003). Adults' reactions to inhaled denatonium benzoate (Bitrex (R)). BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 447-447.

Wilson S, Johnston A, Collier DJ, Caulfield M (2003). Feasibility of enrolling patients to hypertension outcome trials based on an assessment of their cardiovascular risk. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 425-426.

Johnston A, Chusney G, Schütz E, Oellerich M, Lee TD, Holt DW(2003). Monitoring cyclosporin in blood: between-assay differences at trough and 2 hours post-dose (C2). Ther Drug Monit vol. 25, (2) 167-173.

Wilson S, Johnston A, Robson J, Poulter NR, Collier DJ, Feder GS, Caulfield MJ(2003). Predicting coronary risk in the general population--is it necessary to measure high-density lipoprotein cholesterol?. J Cardiovasc Risk vol. 10, (2) 137-141.

Johnston A, Holt D, Lee T, Clark E, Dunn K, Boyce M (2003). Urinary 6 beta-hydroxycortisol: cortisol ratio as an in vivo marker of CYP3A4 activity - spot vs 24 h collections. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 440-440.

He S, Johnston A (2003). Variable ciclosporin exposure: a risk factor for chronic rejection and graft loss?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 434-434.

Johnston AE, Richards IR(2003). Effectiveness of different precipitated phosphates as phosphorus sources for plants. Soil Use and Management vol. 19, (1) 45-49.

Johnston A, Levy GA(2003). The TMC study. LANCET vol. 361, (9354) 346-347.

Mukherjee S, Davies MH, Millson CE, Breslin NP, Johnston A, Levy GA, O'Grady JG, Burroughs A et al.(2003). The TMC study [2] (multiple letters). Lancet vol. 361, (9354) 345-346.

Macphee IAM, Fredericks S, Tai T, Syrris P, Carter ND, Johnston A, Goldberg L, Holt DW(2002). Tacrolimus pharmacogenetics: Polymorphisms associated with expression of cytochrome P4503A5 and P-glycoprotein correlate with dose requirement. TRANSPLANTATION vol. 74, (11) 1486-1489.

Banner NR, David OJ, Leaver N, Davis J, Breen J, Johnston A, Yacoub MH(2002). Pharmacokinetics of oral cyclosporine (Neoral) in heart transplant recipients during the immediate period after surgery. TRANSPLANT INT vol. 15, (12) 649-654.

Wolff CB, Checkley SK, Bhageerutty G, Bhatt H, Johnston A, Collier DJ, Garvie N, Rosenberg ME et al. (2002). Circulation time in man from lung to periphery - pulse and non-pulse oximetry. JOURNAL OF PHYSIOLOGY-LONDON. vol. 543, 41P-41P.

Mcdowell RW, Brookes PC, Mahieu N, Poulton PR, Johnston AE, Sharpley AN(2002). The effect of soil acidity on potentially mobile phosphorus in a grassland soil. Journal of Agricultural Science vol. 139, (1) 27-36.

Wilson S, Johnston A, Robson J, Poulter N, Collier D, Feder G, Caulfield M (2002). Should we measure high density lipoprotein cholesterol in people with hypertension?. JOURNAL OF HYPERTENSION. vol. 20, S150-S150.

Cole E, Midtvedt K, Johnston A, Pattison J, O'Grady C(2002). Recommendations for the implementation of Neoral C-2 monitoring in clinical practice. TRANSPLANTATION vol. 73, (9) S19-S22.

Charmandari E, Pincus SM, Matthews DR, Johnston A, Brook CGD, Hindmarsh PC(2002). Oral hydrocortisone administration in children with classic 21-hydroxylase deficiency leads to more synchronous joint GH and cortisol secretion. J CLIN ENDOCR METAB vol. 87, (5) 2238-2244.

Charmandari E, Johnston A, Honour JW, Brook CGD, Hindmarsh PC(2002). Treatment with flutamide decreases cortisol clearance: Implications for therapy in congenital adrenal hyperplasia. J PEDIATR ENDOCR MET vol. 15, (4) 435-439.

Levy G, Burra P, Cavallari A, Duvoux C, Lake J, Mayer AD, Mies S, Pollard SG et al.(2002). Improved clinical outcomes for liver transplant recipients using cyclosporine monitoring based on 2-hr post-dose levels (C-2). TRANSPLANTATION vol. 73, (6) 953-959.

Trull A, Hughes V, Cooper D, Wilkins M, Gimson A, Friend P, Johnston A, Sharples L et al.(2002). Influence of albumin supplementation on tacrolimus and cyclosporine therapy early after liver transplantation. LIVER TRANSPLANT vol. 8, (3) 224-232.

Kahan BD, Keown P, Levy GA, Johnston A(2002). Therapeutic drug monitoring of inununosuppressant drugs in clinical practice. CLIN THER vol. 24, (3) 330-350.

Ramsey JD, Holt DW, Johnston A(2002). New method to monitor drugs at dance venues - Perhaps results of testing tablets should be made public - Reply. BRIT MED J vol. 324, (7332) 299-300.

Cole J, Ramsey JD, Holt DW, Johnston A(2002). New method to monitor drugs at dance venues [10] (multiple letters). British Medical Journal vol. 324, (7332) 299-300.

Price CP (2002). Biomarkers in renal disease. BIOMARKERS OF DISEASE: AN EVIDENCE-BASED APPROACH. Editors: Trull, A, Demers, LM, Holt, DW, Johnston, A et al., 45-55.

Timms PM, Campbell S, Srikanthan V, Price CP (2002). Matrix metalloproteinases and their tissue inhibitors. BIOMARKERS OF DISEASE: AN EVIDENCE-BASED APPROACH. Editors: Trull, A, Demers, LM, Holt, DW, Johnston, A et al., 379-388.

Johnston AJ, Ascher J, Leadbetter R, Schmith VD, Patel DK, Durcan M, Bentley B(2002). Pharmacokinetic optimisation of sustained-release bupropion for smoking cessation. Drugs vol. 62 Suppl 2, 11-24.

Kirchmann H, Johnston AEJ, Bergström LF(2002). Possibilities for reducing nitrate leaching from agricultural land. Ambio vol. 31, (5) 404-408.

Johnston A (2002). The use of biomarkers for monitoring the response to immunosuppressive drug therapy. BIOMARKERS OF DISEASE: AN EVIDENCE-BASED APPROACH. Editors: Trull, A, Demers, LM, Holt, DW, Johnston, A et al., 451-460.

Meijer SN, Harner T, Helm PA, Halsall CJ, Johnston AE, Jones KC(2001). Polychlorinated naphthalenes in U.K. soils: Time trends, markers of source, and equilibrium status. Environmental Science and Technology vol. 35, (21) 4205-4213.

Charmandari E, Matthews DR, Johnston A, Brook CGD, Hindmarsh PC(2001). Serum cortisol and 17-hydroxyprogesgterone interrelation in classic 21-hydroxylase deficiency: Is current replacement therapy satisfactory?. J CLIN ENDOCR METAB vol. 86, (10) 4679-4685.

Ramsey JD, Butcher MA, Murphy MF, Lee T, Johnston A, Holt DW(2001). A new method to monitor drugs at dance venues. BRIT MED J vol. 323, (7313) 603-603.

Holt DW, Denny K, Lee T, Johnston A (2001). Cyclosporin Measurement - who cares about inaccuracy.?. ACCREDITATION AND QUALITY ASSURANCE. vol. 6, 405-408.

Wilson S, Collier D, Johnston A, Poulter N, Feder G, Robson J, Caulfield M, Anglo-Scandinavian Cardiac Outcomes Trial(2001). Evaluation of cardiovascular risk equations using the ASCOT cohort. J Hum Hypertens vol. 15 Suppl 1, S31-S33.

Charmandari E, Lichtarowicz-Krynska EJ, Hindmarsh PC, Johnston A, Aynsley-Green A, Brook CGD(2001). Congenital adrenal hyperplasia: management during critical illness. ARCH DIS CHILD vol. 85, (1) 26-28.

Shaw G, Johnston A, Holt DW(2001). NHS laboratories can provide a service to the pharmaceutical industry: a personal experience. Ann Clin Biochem vol. 38, (Pt 4) 411-412.

Charmandari E, Hindmarsh PC, Johnston A, Brook CGD(2001). Congenital adrenal hyperplasia due to 21-hydroxylase deficiency: Alterations in cortisol pharmacokinetics at puberty. J CLIN ENDOCR METAB vol. 86, (6) 2701-2708.

Gopaul NK, Manraj MD, Hébé A, Lee Kwai Yan S, Johnston A, Carrier MJ, Anggård EE(2001). Oxidative stress could precede endothelial dysfunction and insulin resistance in Indian Mauritians with impaired glucose metabolism. Diabetologia vol. 44, (6) 706-712.

Green NJL, Jones JL, Johnston AE, Jones KC(2001). Further evidence for the existence of PCDD/Fs in the environment prior to 1900. Environmental Science and Technology vol. 35, (10) 1974-1981.

Meijer SN, Halsall CJ, Harner T, Peters AJ, Ockenden WA, Johnston AE, Jones KC(2001). Organochlorine pesticide residues in archived UK soil. Environmental Science and Technology vol. 35, (10) 1989-1995.

Hardwick JB, Tucker AT, Wilks M, Johnston A, Benjamin N(2001). A novel method for the delivery of nitric oxide therapy to the skin of human subjects using a semi-permeable membrane. Clin Sci (Lond) vol. 100, (4) 395-400.

Charmandari E, Johnston A, Brook CG, Hindmarsh PC(2001). Bioavailability of oral hydrocortisone in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Endocrinol vol. 169, (1) 65-70.

David OJ, Johnston A(2001). Limited sampling strategies for estimating cyclosporin area under the concentration-time curve: review of current algorithms. Ther Drug Monit vol. 23, (2) 100-114.

Charmandari E, Meadows N, Patel M, Johnston A, Benjamin N(2001). Plasma nitrate concentrations in children with infectious and noninfectious diarrhea. J Pediatr Gastroenterol Nutr vol. 32, (4) 423-427.

Farrand P, Rowe RM, Johnston A, Murdoch H(2001). Prevalence, age of onset and demographic relationships of different areca nut habits amongst children in Tower Hamlets, London. Br Dent J vol. 190, (3) 150-154.

Cooney GF, Johnston A(2001). Neoral C-2 monitoring in cardiac transplant patients. Transplant Proc vol. 33, (1-2) 1572-1575.

Cooney GF, Johnston A (2001). Noeral C-2 monitoring in cardiac transplant patients. TRANSPLANTATION PROCEEDINGS. vol. 33, 1572-1575.

Johnston A, Holt DW(2001). Immunosuppressant drugs--the role of therapeutic drug monitoring. Br J Clin Pharmacol vol. 52 Suppl 1, 61S-73S.

Virtanen R, Johnston AE, Crawley MJ, Edwards GR(2000). Bryophyte biomass and species richness on the park grass experiment, Rothamsted, UK. Plant Ecology vol. 151, (2) 129-141.

Holt DW, Johnston A (2000). The impact of cyclosporin formulation on clinical outcomes. TRANSPLANTATION PROCEEDINGS. vol. 32, 1552-1555.

Merton G, Jones K, Lee M, Johnston A, Holt DW(2000). Accuracy of cyclosporin measurements made in capillary blood samples obtained by skin puncture. Therapeutic Drug Monitoring vol. 22, (5) 594-598.

Jones K, Saadat-Lajevardi S, Lee T, Horwatt R, Hicks D, Johnston A, Holt DW(2000). An immunoassay for the measurement of sirolimus. Clinical Therapeutics vol. 22, (SUPPL. B)

Boyce M, Warrington S, Johnston A, Harris A (2000). Effect on gastric pH of repeated doses of YF476, a new gastrin antagonist, compared with omeprazole and placebo. British Journal of Clinical Pharmacology. vol. 50, 383-384.

Johnston AE (2000). Efficient use of nutrients in agricultural production systems. Communications in Soil Science and Plant Analysis. vol. 31, 1599-1620.

Belitsky P, Dunn S, Johnston A, Levy G(2000). Impact of absorption profiling on efficacy and safety of cyclosporin therapy in transplant recipients. Clinical Pharmacokinetics vol. 39, (2) 117-125.

David O, Johnston A, Dumont RJ, Ensom MHH(2000). Limited sampling strategies (multiple letters). Clinical Pharmacokinetics vol. 39, (4)

Holt DW, Lee T, Johnston A(2000). Measurement of sirolimus in whole blood using high-performance liquid chromatography with ultraviolet detection. Clinical Therapeutics vol. 22, (SUPPL. B)

Belitsky P, Levy GA, Johnston A(2000). Neoral absorption profiling: An evolution in effectiveness. Transplantation Proceedings vol. 32, (3) 45S-52S.

Holt DW, Johnston A, Kahan BD, Morris RG, Oellerich M, Shaw LM(2000). New approaches to cyclosporine monitoring raise further concerns about analytical techniques. Clinical Chemistry vol. 46, (6) 872-874.

O'Byrne S, Forte P, Roberts LJ, Morrow JD, Johnston A, Änggård E, Leslie RDG, Benjamin N(2000). Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion. Diabetes vol. 49, (5) 857-862.

Johnston A, David OJ, Cooney GF(2000). Pharmacokinetic validation of neoral absorption profiling. Transplantation Proceedings vol. 32, (3 SUPPL. 1) S53-S56.

Machee IAM, Spreafico S, Bewick M, Davis C, Eastwood JB, Johnston A, Lee T, Holt DW(2000). Pharmacokinetics of mycophenolate mofetil in patients with end-stage renal failure. Kidney International vol. 57, (3) 1164-1168.

Jones K, Johnston A, Holt DW(2000). Proficiency-testing issues relating to sirolimus. Clinical Therapeutics vol. 22, (SUPPL. B)

Higgs B, Johnston AE, Salter JL, Dawson CJ (2000). Some aspects of achieving sustainable phosphorus use in agriculture. Journal of Environmental Quality. vol. 29, 80-87.

Holt DW, Lee T, Jones K, Johnston A(2000). Validation of an assay for routine monitoring of sirolimus using HPLC with mass spectrometric detection. Clinical Chemistry vol. 46, (8 I) 1179-1183.

Ramsey JD, Johnston A, Holt DW, Lind J, Oyefeso A, Pollard M, Baldacchino A, Ghodse H(1999). Death rate from use of ecstasy or heroin (multiple letters) [6]. Lancet vol. 354, (9196) 2166-2167.

Camacho-Hübner C, Woods KA, Miraki-Moud F, Hindmarsh PC, Clark AJ, Hansson Y, Johnston A, Baxter RC et al.(1999). Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion. Journal of Clinical Endocrinology and Metabolism vol. 84, (5) 1611-1616.

Marquet P, Perrin A, Billaud E, Méninat F, Johnston A, Holt DW, Vassault A(1999). Programme de contrôle externe de qualité des dosages de ciclosporine : Synthèse et analyse des résultats des laboratoires français. Annales de Biologie Clinique vol. 57, (3) 360-363.

Johnston A, Holt DW(1999). Bioequivalence criteria for cyclosporine. Transplantation Proceedings vol. 31, (3) 1649-1653.

Johnston A, Holt DW(1999). Therapeutic drug monitoring of immunosuppressant drugs. British Journal of Clinical Pharmacology vol. 47, (4) 339-350.

Zoccali C, Tripepi G, Tucker B, Johnston A, Baker LRI(1999). Ambulatory monitoring and clinic BP measurements for predicting left ventricular mass in patients with chronic renal diseases (multiple letters) [2]. Nephrology Dialysis Transplantation vol. 14, (1) 240-241.

Tilman EA, Tilman D, Crawley MJ, Johnston AE(1999). Biological weed control via nutrient competition: Potassium limitation of dandelions. Ecological Applications vol. 9, (1) 103-111.

Blake L, Goulding KWT, Mott CJB, Johnston AE(1999). Changes in soil chemistry accompanying acidification over more than 100 years under woodland and grass at Rothamsted Experimental Station, UK. European Journal of Soil Science vol. 50, (3) 401-412.

Baker JI, Hites RA, Alcock RE, Jones KC, McLachlan MS, Johnston AE(1999). Comment on 'Evidence for the presence of PCDD/Fs in the environment prior to 1900 and further studies on their temporal trends' [2] (multiple letters). Environmental Science and Technology vol. 33, (1) 205-207.

Holt DW, Johnston A(1999). Delivering quality for the measurement of immunosuppressive drugs: Current performance and future needs. Accreditation and Quality Assurance vol. 4, (9-10) 427-430.

Tucker B, Fabbian F, Giles M, Johnston A, Baker LRI(1999). Reduction of left ventricular mass index with blood pressure reduction in chronic renal failure. Clinical Nephrology vol. 52, (6) 377-382.

Johnston A, Holt DW(1998). Generic substitution for cyclosporine: What should we be looking for in new formulations. Transplantation Proceedings vol. 30, (5) 1652-1653.

Keown P, Kahan BD, Johnston A, Levy G, Dünn SP, Cittero F, Grino JM, Hoyer PF et al.(1998). Optimization of cyclosporine therapy with new therapeutic drug monitoring strategies: Report from the International Neoral® TDM Advisory Consensus Meeting (Vancouver, November 1997). Transplantation Proceedings vol. 30, (5) 1645-1649.

Alcock RE, Mclachlan MS, Johnston AE, Jones KC(1998). Evidence for the presence of PCDD/Fs in the environment prior to 1900 and further studies on their temporal trends. Environmental Science and Technology vol. 32, (11) 1580-1587.

Forte P, Kneale BJ, Milne E, Chowienczyk PJ, Johnston A, Benjamin N, Ritter JM(1998). Evidence for a difference in nitric oxide biosynthesis between healthy women and men. Hypertension vol. 32, (4) 730-734.

Christensen BT, Johnston AE(1997). Chapter 18 Soil organic matter and soil quality-Lessons learned from long-term experiments at Askov and Rothamsted. Developments in Soil Science vol. 25, (C) 399-430.

Holt DW, Johnston A(1997). Tacrolimus quality assessment [1]. Therapeutic Drug Monitoring vol. 19, (2)

Johnston A, Keown PA, Holt DW(1997). Simple bioequivalence criteria: Are they relevant to critical dose drugs? Experience gained from cyclosporine. Therapeutic Drug Monitoring vol. 19, (4) 375-381.

Holt DW, Johnston A(1997). Cyclosporin microemulsion. A guide to usage and monitoring. BioDrugs vol. 7, (3) 175-197.

Holt DW, Johnston A (1997). Monitoring new immunosuppressive agents: Are the methods adequate?. Drug Metabolism and Drug Interactions. vol. 14, 5-15.

Johnston AE(1997). The Value of Long-Term Field Experiments in Agricultural, Ecological, and Environmental Research. vol. 59, (C) 291-333.

Johnston A, Kovarik JM, Mueller EA, Holt DW(1996). Predicting patients' exposure to cyclosporin. Transplant International vol. 9, (SUPPL. 1)

Johnston A(1996). Estrogens - Pharmacokinetics and pharmacodynamics with special reference to vaginal administration and the new estradiol formulation - Estring®. Acta Obstetricia et Gynecologica Scandinavica, Supplement vol. 75, (163) 16-25.

Dalrymple-Hay M, Meara M, Reynolds L, Backhouse L, Wright D, Holt D, Johnston A, Madden B et al. (1996). Changing stable heart transplant recipients from sandimmune to neoral. Transplantation Proceedings. vol. 28, 2285-2286.

Holt DW, Jones K, Lee T, Stadler P, Johnston A (1996). Quality assessment issues of new immunosuppressive drugs and experimental experience. Therapeutic Drug Monitoring. vol. 18, 362-367.

Puthrasingam S, Heybroek WM, Johnston A, Maskrey V, Swift CG, Turner P, Abrams SML, Jackson SHD(1996). Aspartame pharmacokinetics - The effect of ageing. Age and Ageing vol. 25, (3) 217-220.

Holt DW, Johnston A(1996). Immunotherapy in organ transplantation. British journal of hospital medicine vol. 55, (7)

Kjeller LO, Jones KC, Johnston AE, Rappe C(1996). Evidence for a decline in atmospheric emissions of PCDD/Fs in the U.K. Environmental Science and Technology vol. 30, (4) 1398-1403.

Bacon JR, Jones KC, Mcgrath SP, Johnston AE(1996). Isotopic character of lead deposited from the atmosphere at a grassland site in the United Kingdom since 1860. Environmental Science and Technology vol. 30, (8) 2511-2518.

Beck AJ, Harris GL, Howse KR, Johnston AE, Jones KC(1996). Spatial and temporal variation of isoproturon residues and associated sorption/desorption parameters at the field scale. Chemosphere vol. 33, (7) 1283-1295.

Johnston A, Holt DW, Pollard S, Bennett WM, Filler G, Ehrich J, Gennery A, O'Sullivan J et al.(1996). Which cyclosporin formulation? [10]. Lancet vol. 348, (9035) 1175-1177.

Johnston A, Holt DW(1995). Cyclosporine dosing. Transplantation vol. 60, (11) 1376-1377.

Holt DW, Johnston A, Camm AJ, Wolff FW(1995). Fraud in medical science. The Lancet vol. 346, (8971)

Johnston A, Holt DW, Hollander AAMJ, van der Woude FJ, Cohen AF, Yee GC, Lowenthal DT(1995). Effect of grapefruit juice on blood cyclosporin concentration. The Lancet vol. 346, (8967) 122-124.

Beck AJ, Harris GL, Howse KR, Johnston AEJ, Jones KC(1995). Effect of Crop Residue Management and Drainage on the Persistence and Movement of Isoproturon in a Structured Clay Soil over the Growing Season of a Winter Barley Crop. Journal of Agricultural and Food Chemistry vol. 43, (5) 1368-1376.

Jones KC, Johnston AE, McGrath SP(1995). The importance of long- and short-term air-soil exchanges of organic contaminants. International Journal of Environmental Analytical Chemistry vol. 59, (2-4) 167-178.

Holt DW, Johnston A(1995). Commentary on the publication of the study by Plavsić et al., "Bioequivalence of two oral cyclosporine preparations" in Arzneim.-Forsch./Drug Res. 45 (II), No.8, p. 914-917 (1995). Arzneimittel-Forschung vol. 45, (11) 1242-1244.

Johnston A, Holt DW(1995). Concentration-Controlled Trials: What Does the Future Hold?. Clinical Pharmacokinetics vol. 28, (2) 93-99.

Holt DW, Johnston A (1995). Cyclosporin A: Analytical methodology and factors affecting therapeutic drug monitoring. Therapeutic Drug Monitoring. vol. 17, 625-630.

Sardina M, Warrington SJ, Boyce M, Johnston A, Bianchini C(1995). Hemodynamic and humoral effects at rest and after head-up tilt tests during 24-hour infusion of a new nitrate ester, ITF 296, compared with ISDN and placebo in healthy volunteers: A double-blind, randomized, within-subject study. Journal of Cardiovascular Pharmacology vol. 26, (4) S80-S90.

Flückiger SS, Schmidt C, Meyer A, Kallay Z, Johnston A, Kutz K(1995). Pharmacokinetics of Orally Administered Cyclosporine in Patients with Crohn's Disease. The Journal of Clinical Pharmacology vol. 35, (7) 681-687.

Nicholson FA, Jones KC, Johnston AE(1995). The significance of the retention of atmospherically deposited cadmium on plant surfaces to the cadmium content of herbage. Chemosphere vol. 31, (4) 3043-3049.

Nicholson FA, Jones KC, Johnston AE(1994). Effect of Phosphate Fertilizers and Atmospheric Deposition on Long-Term Changes in the Cadmium Content of Soils and Crops. Environmental Science and Technology vol. 28, (12) 2170-2175.

Holt DW, Johnston A, Ramsey JD(1994). Breath pentane and heart rejection [4]. Journal of Heart and Lung Transplantation vol. 13, (6) 1147-1148.

Colin Long C, Hill SA, Thomas RC, Johnston A, Smith SG, Kendall F, Finlay AY(1994). Effect of terbinafine on the pharmacokinetics of cyclosporin in humans. Journal of Investigative Dermatology vol. 102, (5) 740-743.

Johnston AE, Mcewen J, Lane PW, Hewitt MV, Poulton PR, Yeoman DP(1994). Effects of One to Six Year Old Ryegrass—Clover Leys on Soil Nitrogen and on the Subsequent Yields and Fertilizer Nitrogen Requirements of the Arable Sequence Winter Wheat, Potatoes, Winter Wheat, Winter Beans (Vicia Faba) Grown on a Sandy Loam Soil. The Journal of Agricultural Science vol. 122, (1) 73-89.

Munroe PB, Johnston A, Duke VM, Daniel HI, Bouloux PM, Lawson M, Caulfield MJ (1994). Investigation of lipoprotein lipase (LPL) as a candidate gene for dyslipidaemic hypertension. Journal of Human Hypertension. vol. 8, 613-614.

Seymour MT, Patel N, Johnston A, Joel SP, Slevin ML(1994). Lack of effect of interferon α2a upon fluorouracil pharmacokinetics. British Journal of Cancer vol. 70, (4) 724-728.

Holt DW, Johnston A, Roberts NB, Tredger JM, Trull AK(1994). Methodological and clinical aspects of cyclosporin monitoring: Report of the Association of Clinical Biochemists task force. Annals of Clinical Biochemistry vol. 31, (5) 420-446.

Blake L, Johnston AE, Goulding KWT(1994). Mobilization of aluminium in soil by acid deposition and its uptake by grass cut for hay – a Chemical Time Bomb. Soil Use and Management vol. 10, (2) 51-55.

Farthing MJG, Alstead EM, Abrams SML, Haug G, Johnston A, Hermann R, Niebch G, Ruus P et al.(1994). Pharmacokinetics of naftopidil, a novel anti-hypertensive drug, in patients with hepatic dysfunction. Postgraduate Medical Journal vol. 70, (823) 363-366.

Johnston AE(1994). The role of nitrogen in crop production and losses of nitrate by leaching from agricultural soil. Marine Pollution Bulletin vol. 29, (6-12) 414-419.

Jenkinson DS, Potts JM, Perry JN, Barnett V, Coleman K, Johnston AE(1994). Trends in Herbage Yields Over the Last Century on the Rothamsted Long-Term Continuous Hay Experiment. The Journal of Agricultural Science vol. 122, (3) 365-374.

Johnston A, Holt DW, Jensen T(1993). Calibration of the CYCLO-Trac SP cyclosporine radioimmunoassay [5]. Clinical Chemistry vol. 39, (12) 2532-2533.

Hart PBS, Powlson DS, Poulton PR, Johnston AE, Jenkinson DS(1993). The availability of the nitrogen in the crop residues of winter wheat to subsequent crops. The Journal of Agricultural Science vol. 121, (3) 355-362.

Ravic M, Salas-Herrera I, Johnston A, Turner P, Foley K, Rosenow DE(1993). A pharmacokinetic interaction between cimetidine or ranitidine and lornoxicam. Postgraduate Medical Journal vol. 69, (817) 865-866.

Kovarik JM, Mueller EA, Johnston A, Hitzenberger G, Kutz K(1993). Bioequivalence of Soft Gelatin Capsules and Oral Solution of a New Cyclosporine Formulation. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy vol. 13, (6) 613-617.

Johnston A, Abrams SML, Patel M, Shah G, Berti C, Dubini A, Strolin-Benedetti M, Turner P (1993). Bioequivalence of controlled release nicergoline 60 mg once daily vs the plain form 30 mg twice daily in 24 male subjects. British Journal of Clinical Pharmacology. vol. 35,

Lledó P, Johnston A, Pearson RM, Turner P(1993). Determination of Oxidation Phenotype by Measurement of Propafenone Urinary Metabolic Ratios. Human & Experimental Toxicology vol. 12, (2) 161-163.

Johnston A, Holt DW(1993). External quality assessment scheme for cyclosporin in body fluids. Scandinavian Journal of Clinical and Laboratory Investigation vol. 53, (S212) 48-53.

Lledó P, Abrams SML, Johnston A, Patel M, Pearson RM, Turner P(1993). Influence of debrisoquine hydroxylation phenotype on the pharmacokinetics of mexiletine. European Journal of Clinical Pharmacology vol. 44, (1) 63-67.

Ravic M, Salas¿Herrera I, Johnston A, Turner P, Foley K, Rosenow D(1993). Influence of lornoxicam a new non‐steroidal antiinflammatory drug on lithium pharmacokinetics. Human Psychopharmacology: Clinical and Experimental vol. 8, (4) 289-292.

Alcock RE, Johnston AE, McGrath SP, Berrow ML, Jones KC(1993). Long-Term Changes in the Polychlorinated Biphenyl Content of United Kingdom Soils. Environmental Science and Technology vol. 27, (9) 1918-1923.

Haygarth PM, Cooke AI, Jones KC, Harrison AF, Johnston AE(1993). Long-term change in the biogeochemical cycling of atmospheric selenium: deposition to plants and soil. Journal of Geophysical Research vol. 98, (D9)

Mueller EA, Kovarik JM, Koelle EU, Merdjan H, Johnston A, Hitzenberger G(1993). Pharmacokinetics of Cyclosporine and Multiple‐Dose Diclofenac During Coadministration. The Journal of Clinical Pharmacology vol. 33, (10) 936-943.

Kovarik JM, Mueller EA, Gaber M, Johnston A, Jähnchen E(1993). Pharmacokinetics of Cyclosporine and Steady‐State Aspirin During Coadministration. The Journal of Clinical Pharmacology vol. 33, (6) 513-521.

Holt DW, Marwaha G, Jones K, Johnston A (1993). Quality assurance programs for immunosuppressive drugs: Cyclosporine and beyond. Therapeutic Drug Monitoring. vol. 15, 472-477.

Jones KC, Andrew J, Johnston AE(1992). Evidence for an Increase in the Cadmium Content of Herbage Since the 1860s. Environmental Science and Technology vol. 26, (4) 834-836.

Griffiths E, Patel P, Johnston A, Abrams SML (1992). Avena sativa compound: A herbal sedative?. British Journal of Clinical Pharmacology. vol. 33,

Holt DW, Johnston A (1992). Cyclosporin monitoring: Its role in autoimmune indications. Journal of Autoimmunity. vol. 5, 177-182.

Ravic M, Johnston A, Turner P, Foley K, Rosenow D(1992). Does Bismuth Chelate Influence Lornoxicam Absorption?. Human & Experimental Toxicology vol. 11, (1) 59-60.

Jones KC, Sanders G, Wild SR, Burnett V, Johnston AE(1992). Evidence for a decline of PCBs and PAHs in rural vegetation and air in the United Kingdom. Nature vol. 356, (6365) 137-140.

Powlson DS, Poulton PR, Johnston AE, Jenkinson DS(1992). Influence of soil type, crop management and weather on the recovery of 15N-labelled fertilizer applied to winter wheat in spring. The Journal of Agricultural Science vol. 118, (1) 83-100.

Wild SR, Jones KC, Johnston AE(1992). The polynuclear aromatic hydrocarbon (PAH) content of herbage from a long-term grassland experiment. Atmospheric Environment Part A, General Topics vol. 26, (7) 1299-1307.

Conlon D, Johnston A, Turner P, O'Malley K, Kilfeather S(1991). Hepatic β-adrenoceptor adaptation during propranolol administration is impaired in ageing rats. European Journal of Pharmacology: Molecular Pharmacology vol. 208, (4) 323-330.

Hossein-Nia M, Devlin JJ, Fagbohun M, Tredger JM, Williams R, Johnston A, Holt DW (1991). Urinary proteins as a marker of drug-induced renal damage following treatment with cyclosporine or FK 506. Transplantation Proceedings. vol. 23, 3150-3152.

Holt DW, Johnston A(1991). Cyclosporin and vitamin E. The Lancet vol. 338, (8768)

Johnston A, Holt DW, Wilkie M, Berth-Jones J, Sowden JM, Feehally J, Graham-Brown R, Madeley P(1991). Treatment of severe refractory atopic dermatitis with cyclosporin. The Lancet vol. 338, (8767) 643-644.

Kjeller LO, Rappe C, Jones KC, Johnston AE(1991). Increases in the Polychlorinated Dibenzo-p-dioxin and -furan Content of Soils and Vegetation since the 1840s. Environmental Science and Technology vol. 25, (9) 1619-1627.

Salas-herrera IG, Pearson RM, Jhonston A, Turner P(1991). Concentration of metronidazole in cenical mucus and serum after single and repeated oral doses. Journal of Antimicrobial Chemotherapy vol. 28, (2) 283-289.

Jones KC, Johnston AE(1991). Significance of Atmospheric Inputs of Lead to Grassland at One Site in the United Kingdom since 1860. Environmental Science and Technology vol. 25, (6) 1174-1178.

Johnston AE(1991). Benefits from long-term ecosystem research: some examples from Rothamsted. Long-term ecological research89-113.

Fashola TOA, Johnston A, Counihan P, Pepper JR, Holt DW (1991). Blood cyclosporin absorption profiles and renal function in heart transplant recipients. British Journal of Clinical Pharmacology. vol. 31,

Walker S, Johnston A(1991). Laboratory screening of body fluids in self poisoning and drug abuse. Annals of the Academy of Medicine, Singapore vol. 20, (1) 91-94.

Holt DW, Fashola TOA, Johnston A (1991). Monitoring cyclosporin: is it still important?. Immunology Letters. vol. 29, 99-103.

Salas¿Herrera I, Lawson M, Johnston A, Turner P, Gott D, Dennis M(1991). Plasma metronidazole concentrations after single and repeated vaginal pessary administration. British Journal of Clinical Pharmacology vol. 32, (5) 621-623.

Johnston A, Cullen G, Holt DW(1991). Quality assurance for cyclosporin in body fluids. Annals of the Academy of Medicine Singapore vol. 20, (1) 3-8.

Ravic M, Johnston A, Turner P, Takacs F, Rosenow DE(1991). The Effect of Repeated Oral Doses of Lornoxicam on Antipyrine Elimination in Normal Human Volunteers. Human & Experimental Toxicology vol. 10, (5) 375-377.

Holt DW, Walker S, Johnston A, Jones RW, Howse NL, Darragh A, Caffrey E(1991). The effect of age on the pharmacokinetics of pentisomide. Biopharmaceutics & Drug Disposition vol. 12, (8) 627-631.

Edeki T, Johnston A, Turner P(1990). An examination of a possible pharmacokinetic interaction between nifedipine and antipyrine. European Journal of Clinical Pharmacology vol. 39, (4) 405-407.

Kahan BD, Shaw LM, Holt D, Grevel J, Johnston A(1990). Consensus document: Hawk's Cay Meeting on therapeutic drug monitoring of cyclosporine. Clinical Chemistry vol. 36, (8 I) 1510-1516.

Saleh S, Johnston A, Turner P(1990). Medifoxamine: Oral tolerance and pharmacokinetic study in healthy human volunteers. European Journal of Clinical Pharmacology vol. 39, (2) 169-171.

Robinson K, Johnston A, Walker S, Mulrow J, Holt D, McKenna W(1990). Stability of plasma amiodarone levels during chronic oral therapy. Cardiovascular Drugs and Therapy vol. 4, (2) 529-530.

Ravic M, Johnston A, Turner P, Ferber HP(1990). A Study of the Interaction between Lornoxicam and Warfarin in Healthy Volunteers. Human & Experimental Toxicology vol. 9, (6) 413-414.

Johnston A, Sketris I, Marsden JT, Galustian CG, Fashola T, Taube D, Pepper J, Holt DW(1990). A limited samping strategy for the measurement of cyclosporine AUC. Transplantation Proceedings vol. 22, (3) 1345-1346.

Saleh S, Johnston A, Turner P(1990). Absolute bioavailability and pharmacokinetics of medifoxamine in healthy humans. British Journal of Clinical Pharmacology vol. 30, (4) 621-624.

Saleh S, Johnston A, Turner P (1990). Absolute bioavailability of medifoxamine in healthy human volunteers. British Journal of Clinical Pharmacology. vol. 29,

Heybroek WM, Caulfield M, Johnston A, Turner P(1990). Automatic on-line extraction coupled with electrochemical detection as an improved method for the HPLC co-analysis of codeine and morphine in plasma and gastric juice. Journal of Pharmaceutical and Biomedical Analysis vol. 8, (8-12) 1021-1027.

Warrington SJ, Johnston A, Lewis Y, Murphy M(1990). Bisoprolol: Studies of potential interactions with theophylline and warfarin in healthy volunteers. Journal of Cardiovascular Pharmacology vol. 16, S164-S168.

Turner P, Johnston A (1990). Clinical pharmacokinetic studies with lornoxicam. Postgraduate Medical Journal. vol. 66,

Ravic M, Johnston A, Turner P (1990). Clinical pharmacological studies of some possible interactions of lornoxicam with other drugs. Postgraduate Medical Journal. vol. 66,

Holt DW, Johnston A(1990). Cyclosporin assay techniques. Accuracy and reproducibility variables impacting on measurements. International Journal of Radiation Applications and Instrumentation. vol. 17, (7) 733-736.

Saleh S, Caulfield M, Lledo P, Johnston A, Turner P (1990). Debrisoquine-type genetic polymorphism differences in medifloxamine pharmacokinetics. European Journal of Pharmacology. vol. 183,

Warrington SJ, Sinclair AJ, Johnston A(1990). Effects of single doses of a 20 mg frusemide/2.5 mg amiloride combination, 20 mg frusemide and placebo on plasma and urine electrolytes in healthy men. Journal of International Medical Research vol. 18, (SUPPL. 2)

Warrington SJ, Debbas NMG, Farthing M, Horton M, Johnston A, Thillainayagam A, Turner P, Ferber H(1990). Lornoxicam, indomethacin and placebo: Comparison of effects on faecal blood loss and upper gastrointestinal endoscopic appearances in healthy men. Postgraduate Medical Journal vol. 66, (778) 622-626.

Saleh S, Johnston A, Turner P(1990). Measurement of medifoxamine metabolites in urine by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications vol. 528, (C) 531-536.

Lledo P, Abrams SML, Johnston A, Pearson RM (1990). Mexiletine pharmacokinetics and debrisoquine hydroxylator status. European Journal of Pharmacology. vol. 183,

Holt DW, Marsden JT, Fashola TOA, Johnston A(1990). Performance of the Sandoz radioimmunoassays for cyclosporine. Transplantation Proceedings vol. 22, (3) 1155-1159.

Holt DW, Marsden JT, Johnston A (1990). Quality assessment of cyclosporine measurements: Comparison of current methods. Transplantation Proceedings. vol. 22, 1234-1239.

Warrington SJ, Lewis Y, Dawnay A, Johnston A, Kovacs IB, Lamb E, Ravic M (1990). Renal and gastrointestinal tolerability of lornoxicam, and effects on haemostasis and hepatic microsomal oxidation. Postgraduate Medical Journal. vol. 66,

Saleh S, Johnston A, Edeki T, Turner P(1990). Tolerability and kinetics of intravenous medifoxamine in healthy volunteers. International Clinical Psychopharmacology vol. 5, (2) 97-102.

Taube D, Marsden J, Palmer A, Cairns T, Johnston A, Holt DW(1990). Value of cyclosporine measurements in renal transplant recipients immunosuppressed with triple therapy. Transplantation Proceedings vol. 22, (3) 1251-1252.

Robinson K, Johnston A, Walker S, Holt DW, McKenna WJ(1989). Effects of amiodarone on the kinetics of antipyrine. The American Journal of Cardiology vol. 63, (13) 991-992.

Jones KC, Johnston AE(1989). Cadmium in cereal grain and herbage from long-term experimental plots at Rothamsted, UK. Environmental Pollution vol. 57, (3) 199-216.

Jones KC, Grimmer G, Jacob J, Johnston AE(1989). Changes in the polynuclear aromatic hydrocarbon content of wheat grain and pasture grassland over the last century from one site in the U.K. Science of the Total Environment, The vol. 78, (C) 117-130.

Warrington SJ, Dawnay A, Johnston A, Saul S, Turner P, Ferber HP(1989). Chlortenoxicam and renal function of normal human volunteers. Human & Experimental Toxicology vol. 8, (1) 53-54.

Holt DW, Marsden JT, Johnston A, Taube DH(1989). Cyclosporine monitoring with polyclonal and specific monoclonal antibodies during episodes of renal allograft dysfunction. Transplantation Proceedings vol. 21, (1 II) 1482-1484.

Saleh S, Johnston A, Chanon M, Turner P(1989). Determination of medifoxamine in plasma and urine by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications vol. 496, (C) 223-227.

OMAR OA, HOSKIN PJ, JOHNSTON A, HANKS GW, TURNER P(1989). Diamorphine stability in aqueous solution for subcutaneous infusion. Journal of Pharmacy and Pharmacology vol. 41, (4) 275-277.

Jones KC, Stratford JA, Waterhouse KS, Furlong ET, Giger W, Hites RA, Schaffner C, Johnston AE(1989). Increases in the Polynuclear Aromatic Hydrocarbon Content of an Agricultural Soil over the Last Century. Environmental Science and Technology vol. 23, (1) 95-101.

Abrams SML, Pierce DM, Johnston A, Hedges A, Franklin RA, Turner P(1989). Pharmacokinetic Interaction Between Indoramin and Ethanol. Human & Experimental Toxicology vol. 8, (3) 237-241.

Flanagan R, Johnston A, White A, Crome P(1989). Pharmacokinetics of dextropropoxyphene and nordextropropoxyphene in young and elderly volunteers after single and multiple dextropropoxyphene dosage. British Journal of Clinical Pharmacology vol. 28, (4) 463-469.

Jones KC, Stratford JA, Tidridge P, Waterhouse KS, Johnston AE(1989). Polynuclear aromatic hydrocarbons in an agricultural soil: Long-term changes in profile distribution. Environmental Pollution vol. 56, (4) 337-351.

Goulding KWT, McGrath SP, Johnston AE(1989). Predicting the lime requirement of soils under permanent grassland and arable crops. Soil Use and Management vol. 5, (2) 54-58.

Johnston A, Marsden JT, Holt DW(1989). The continuing need for quality assessment of cyclosporine measurement. Clinical Chemistry vol. 35, (7) 1309-1312.

Robinson K, Johnston A, Walker S, Mulrow JP, McKenna WJ, Holt DW(1989). The digoxin-amiodarone interaction. Cardiovascular Drugs and Therapy vol. 3, (1) 25-28.

Edeki T, Johnston A, Turner P(1989). The effect of nifedipine on hepatic drug oxidizing enzymes (Abstract). Postgraduate Medical Journal vol. 65, (SUPPL. 1)

Hoskin PJ, Alsayed-Omar O, Hanks GW, Johnston A, Turner P(1989). The influence of blood sample preparation on measured levels of morphine and its major metabolites. Annals of Clinical Biochemistry vol. 26, (2) 182-184.

Jackson SHD, Johnston A, Woollard R, Turner P(1989). The relationship between theophylline clearance and age in adult life. European Journal of Clinical Pharmacology vol. 36, (1) 29-34.

Holt DW, Johnston A(1989). The relevance of pharmacokinetics to monitoring new antiarrhythmics. Clinical Chemistry vol. 35, (7) 1332-1336.

Johnston A, Holt DW, Kirk AJB, Bateman DN, Dark JH(1988). CYCLOSPORIN RADIOIMMUNOASSAY AND CARDIAC TRANSPLANTATION. The Lancet vol. 332, (8608)

Johnston A, Hedges A, Turner P(1988). A Study of the Interaction between Oxytetracycline and Pyridostigmine. Human & Experimental Toxicology vol. 7, (3) 263-266.

Lewis R, Maclean D, Ioannides C, Johnston A, McDevitt D(1988). A comparison of bisoprolol and atenolol in the treatment of mild to moderate hypertension. British Journal of Clinical Pharmacology vol. 26, (1) 53-59.

Randhawa MA, Hedges A, Johnston A, Turner P(1988). A psychopharmacological study to assess anti‐muscarinic and central nervous effects of medifoxamine in normal volunteers. Human Psychopharmacology: Clinical and Experimental vol. 3, (3) 195-200.

Ankier SI, Brimelow AE, Crome P, Johnston A, Warrington SJ, Turner P, Ferber HP(1988). Chlortenoxicam pharmacokinetics in young and elderly human volunteers. Postgraduate Medical Journal vol. 64, (756) 752-754.

Jackson S, Johnston A, Woollard R, Abrams S, Turner P(1988). Circadian variation in theophylline absorption during chronic dosing with a slow release theophylline preparation and the effect of clock time of dosing. British Journal of Clinical Pharmacology vol. 26, (1) 73-77.

Jackson SHD, Johnston A(1988). Intraindividual variation in theophylline pharmacokinetics - The application of repeatability analysis. British Journal of Clinical Pharmacology vol. 25, (5)

Holt DW, Johnston A, Marsden JT, Vernillet L, Keown PA, Rosano TG, Shaw LM, Rosenthaler J(1988). Monoclonal antibodies for radioimmunoassay of cyclosporine: A multicenter comparison of their performance with the Sandoz polyclonal radioimmunoassay kit. Clinical Chemistry vol. 34, (6) 1091-1096.

Marsden JT, Johnston A, Holt DW(1988). Monoclonal antibodies for the radioimmunoassay of cyclosporine. Transplantation Proceedings vol. 20, (2 SUPPL. 2) 319-322.

Abrams SML, Baker LRI, Crome P, White AST, Johnston A, Ankier SI, Warrington SJ, Turner P et al.(1988). Pharmacokinetics of flupirtine in elderly volunteers and in patients with moderate renal impairment. Postgraduate Medical Journal vol. 64, (751) 361-363.

Johnston A, Marsden JT, Holt DW(1988). Recent developments in ciclosporin measurements. Bibliotheca cardiologica (43) 60-62.

Poulain P, Hoskin PJ, Hanks GW, A-omar O, Walker VA, Johnston A, Turner P, Aherne GW(1988). Relative bioavailability of controlled release morphine tablets (mst continus) in cancer patients. British Journal of Anaesthesia vol. 61, (5) 569-574.

JOHNSTON A, WARRINGTON SJ, TURNER P, AURLCH R(1988). The effect of repeated oral doses of azelastine hydrochloride on antipyrine half‐life in normal volunteers. Journal of Pharmacy and Pharmacology vol. 40, (3) 225-225.

Johnston A, Marsden J, Holt D(1988). The influence of haematocrit on blood cyclosporin measurements in vivo. British Journal of Clinical Pharmacology vol. 25, (4) 509-513.

Payton CD, Fox JG, Pauleau NF, Boulton-Jones JM, Ioannides C, Johnston A, Thomas P(1987). The single dose pharmacokinetics of bisoprolol (10 mg) in renal insufficiency: The clinical significance of balanced clearance. European Heart Journal vol. 8, (SUPPL. M) 15-22.

Johnston A, Warrington SJ, Turner P, Riethmuller-Winzen H(1987). Comparison of flupirtine and indomethacin on frusemideinduced diuresis. Postgraduate Medical Journal vol. 63, (745) 959-961.

Al¿Sayed¿Omar O, Johnston A, Turner P(1987). Influence of pH on the buccal absorption of morphine sulphate and its major metabolite, morphine‐3‐glucuronide. Journal of Pharmacy and Pharmacology vol. 39, (11) 934-935.

Ong ML, Jackson G, Johnston A, Bhamra R, Holt DW(1987). Plasma flecainide concentrations following acute myocardial infarction. International Journal of Cardiology vol. 15, (3) 341-346.

Jones KC, Symon CJ, Johnston AE(1987). Retrospective analysis of an archived soil collection I. Metals. Science of the Total Environment, The vol. 61, (C) 131-144.

Jones KC, Symon CJ, Johnston AE(1987). Retrospective analysis of an archived soil collection II. Cadmium. Science of the Total Environment, The vol. 67, (1) 75-89.

Johnston A, Marsden JT, Holt DW(1987). Sample pretreatment to minimize interference from whole blood in the radioimmunoassay for cyclosporine. Transplantation vol. 44, (2)

Johnston AE(1987). Saxmundham Experimental Station 1899-1986. A review of the achievements during 1965-1986 ( UK). Rothamsted Experimental Station, report for 1986, (Lawes Agricultural Trust)265-279.

Hayes PC, Jenkins D, Vavianos P, Dagap K, Johnston A, Ioannides C, Thomas P, Williams R(1987). Single oral dose pharmacokinetics of bisoprolol 10 mg in liver disease. European Heart Journal vol. 8, (SUPPL. M) 23-29.

Harvey VJ, Slevin ML, Aherne GW, Littleton P, Johnston A, Wrigley PF(1987). Subcutaneous infusion of bleomycin - A practical alternative to intravenous infusion. Journal of Clinical Oncology vol. 5, (4) 648-650.

Jackson S, Jamieson M, Johnston A, Shepherd A(1987). The analysis of dose‐response curves‐a practical approach. British Journal of Clinical Pharmacology vol. 23, (2) 199-205.

Pasic J, Jackson SHD, Johnston A, Peverel-Cooper CA, Turner P, Downey K, De Saintonge DMC(1987). The interaction between chronic oral slow-release theophylline and single-dose intravenous erythromycin. Xenobiotica vol. 17, (4) 493-497.

Holt DW, Marsden JT, Johnston A(1986). Measurement of cyclosporine: Methodological problems. Transplantation Proceedings vol. 18, (6 SUPPL. 5) 101-110.

Harvey VJ, Slevin ML, Joel SP, Johnston A, Wrigley PFM(1986). The effect of dose on the bioavailability of oral etoposide. Cancer Chemotherapy And Pharmacology vol. 16, (2) 178-181.

ROTHBAUM HP, GOGUEL RL, JOHNSTON AE, MATTINGLY GEG(1986). Cadmium accumulation in soils from long‐continued applications of superphosphate. Journal of Soil Science vol. 37, (1) 99-107.

Johnston AE, Goulding KWT, Poulton PR(1986). Soil acidification during more than 100 years under permanent grassland and woodland at Rothamsted. Soil Use and Management vol. 2, (1) 3-10.

Johnston AE(1986). Soil organic matter, effects on soils and crops. Soil Use and Management vol. 2, (3) 97-105.

Debbas N, Jackson S, Shah K, Abrams S, Johnston A, Turner P(1986). The bioavailability and pharmacokinetics of slow release nifedipine during chronic dosing in volunteers. British Journal of Clinical Pharmacology vol. 21, (4) 385-388.

Johnston A, Marsden J, Hla K, Henry J, Holt D(1986). The effect of vehicle on the oral absorption of cyclosporin. British Journal of Clinical Pharmacology vol. 21, (3) 331-333.

Jackson S, Shah K, Debbas N, Johnston A, Peverel¿Cooper C, Turner P(1986). The interaction between i.v. theophylline and chronic oral dosing with slow release nifedipine in volunteers. British Journal of Clinical Pharmacology vol. 21, (4) 389-392.

Powlson DS, Pruden G, Johnston AE, Jenkinson DS(1986). The nitrogen cycle in the Broadbalk Wheat Experiment: Recovery and losses of¹⁵N-labelled fertilizer applied in spring and inputs of nitrogen from the atmosphere. The Journal of Agricultural Science vol. 107, (3) 591-609.

Johnston A, Marsden JT, Holt DW(1986). The united kingdom cyclosporin quality assessment scheme. Therapeutic Drug Monitoring vol. 8, (2) 200-204.

Caplin JL, Johnston A, Hamer J, Camm AJ(1985). The acute changes in serum binding of disopyramide and flecainide after myocardial infarction. European Journal of Clinical Pharmacology vol. 28, (3) 253-255.

Pearson RM, Ridgway EJ, Johnston A, Vadukul J(1985). Concentration of d-propranolol in cervico-vaginal mucus: targeting of a novel spermicide. Advances in Contraception vol. 1, (1) 103-108.

Jackson SHD, Wiffen JK, Johnston A, Peverel-Cooper CA(1985). The relationship between clearance of theophylline and age within the adult age range. European Journal of Clinical Pharmacology vol. 29, (2) 177-179.

Johnston A, Warrington S, Turner P(1985). An attempt to estimate the absolute bioavailability of flecainide without reference to a parenteral dose. Pharmaceutical Medicine vol. 1, (2) 105-109.

Johnston A, Warrington S, Turner P(1985). Flecainide pharmacokinetics in healthy volunteers: the influence of urinary pH. British Journal of Clinical Pharmacology vol. 20, (4) 333-338.

Harvey VJ, Joel SP, Johnston A, Slevin ML(1985). High-performance liquid chromatography of etoposide in plasma and urine. Journal of Chromatography B: Biomedical Sciences and Applications vol. 339, (C) 419-423.

Johnston AE, Powlson DS(1985). Straw incorporation - what about nitrogen?. Soil & Water (Banbury) vol. 13, (2) 12-13.

Harvey VJ, Slevin ML, Joel SP, Johnston A, Wrigley PFM(1985). The effect of food and concurrent chemotherapy on the bioavailability of oral etoposide. British Journal of Cancer vol. 52, (3) 363-367.

Powlson DS, Jenkinson DS, Pruden G, Johnston AE(1985). The effect of straw incorporation on the uptake of nitrogen by winter wheat. Journal of the Science of Food and Agriculture vol. 36, (1) 26-30.

Harvey VJ, Slevin ML, Joel SP, Smythe MM, Johnston A, Wrigley PFM(1985). Variable bioavailability following repeated oral doses of etoposide. European Journal of Cancer and Clinical Oncology vol. 21, (11) 1315-1319.

Johnston A(1985). simp: A computer program in basic for nonlinear curve fitting. Journal of Pharmacological Methods vol. 14, (4) 323-329.

Pearson RM, Ridgway EJ, Johnston A, Vadukul J(1984). CONCENTRATION OF D-PROPRANOLOL IN CERVICOVAGINAL MUCUS. The Lancet vol. 324, (8417-8418)

Jackson SHD, Wiffen JK, Johnston A, Peverel-Cooper CA(1984). The disposition of inhaled lysine theophylline in volunteers. European Journal of Clinical Pharmacology vol. 26, (5) 635-637.

Slevin ML, Piall EM, Johnston A, Levison DA, Aherne GW, Tree SB, Lister TA(1984). The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension. Investigational New Drugs vol. 2, (3) 271-276.

Harvey VJ, Slevin ML, Woollard RC, Johnston A, Barnett MJ, Wrigley PFM, Turner P(1984). The bioavailability of oral intermediate-dose methotrexate - Effect of dose subdivision, formulation, and timing in the chemotherapy cycle. Cancer Chemotherapy and Pharmacology vol. 13, (2) 91-94.

Slevin ML, Harvey VJ, Aherne GW, Burton NK, Johnston A, Wrigley PFM(1984). Delayed-release bleomycin - Comparative pharmacology of bleomycin oil suspension and bleomycin in saline. Cancer Chemotherapy and Pharmacology vol. 13, (1) 19-21.

Slevin ML, Ang LM, Johnston A, Turner P(1984). The efficiency of protective gloves used in the handling of cytotoxic drugs. Cancer Chemotherapy and Pharmacology vol. 12, (3) 151-153.

Taylor RH, Carter P, Johnston A(1984). ENHANCEMENT OF AEROSOL ABSORPTION IN MAN. The Lancet vol. 323, (8377)

Jackson SH, Wiffen JK, Smythe MM, Johnston A(1984). Is circadian variation in theophylline trough levels determined by time of dosing?. British journal of clinical practice. Supplement vol. 32, 7-9.

Jackson S, Wiffen J, Smythe M, Johnston A(1984). Is circadian variation in theophylline trough serum concentrations determined by time of dosing?. British Journal of Clinical Pharmacology vol. 17, (6) 777-779.

Patel L, Johnston A, Turner P(1984). Nadolol binding to human serum proteins. Journal of Pharmacy and Pharmacology vol. 36, (6) 414-415.

Matheson I, Plowman PN, Johnston A(1984). Pharmacokinetic considerations of misonidazole in therapeutics. Human Toxicology vol. 3, (1) 29-36.

Warrington S, Holt D, Johnston A, Fitzsimons T(1984). Pharmacokinetics and pharmacodynamics of verapamil in combination with atenolol, metoprolol and propranolol. British Journal of Clinical Pharmacology vol. 17, (1 S) 37S-44S.

Harvey V, Slevin M, Dilloway M, Clark P, Johnston A, Lant A(1984). The influence of cimetidine on the pharmacokinetics of 5‐fluorouracil. British Journal of Clinical Pharmacology vol. 18, (3) 421-430.

Muhiddin K, Johnston A, Turner P(1984). The influence of urinary pH on flecainide excretion and its serum pharmacokinetics. British Journal of Clinical Pharmacology vol. 17, (4) 447-451.

Slevin ML, Johnston A, Woollard RC, Piall EM, Lister TA, Turner P(1983). Relationship between protein binding and extravascular drug concentrations of a water-soluble drug, cytosine arabinoside. Journal of the Royal Society of Medicine vol. 76, (5) 365-368.

Johnston A, Woollard RC(1983). STRIPE: An interactive computer program for the analysis of drug pharmacokinetics. Journal of Pharmacological Methods vol. 9, (3) 193-199.

Slevin ML, Piall EM, Aherne GW, Johnston A, Lister TA(1983). Subcutaneous infusion of cytosine arabinoside - A practical alternative to intravenous infusion. Cancer Chemotherapy and Pharmacology vol. 10, (2) 112-114.

Slevin ML, Piall EM, Aherne GW, Johnston A, Lister TA(1983). The clinical pharmacology of cytosine arabinoside. Hamatologie und Bluttransfusion vol. 28, 70-75.

Johnston A, ALDHOUS ME, Hedges A, Weerasuriya K, Freedman A, Turner P(1983). The pharmacokinetics of lysine theophylline, a new soluble theophylline, in human volunteers. Postgraduate Medical Journal vol. 59, (688) 86-87.

Al-Damluji S, Nathan AW, Johnston A, Banim SO, Spurrell RAJ, Camm AJ(1982). Oral theophylline in chronic heart failure. Postgraduate Medical Journal vol. 58, (678) 216-221.

Iliopoulou A, Aldhous M, Johnston A, Turner P(1982). Pharmacokinetic interaction between theophylline and erythromycin. British Journal of Clinical Pharmacology vol. 14, (4) 495-499.

Culig J, Johnston A, Turner P(1982). Saliva theophylline concentrations after a single oral dose. British Journal of Clinical Pharmacology vol. 13, (2) 243-245.

Johnston AE(1982). The effects of farming systems on the amount of soil organic matter and its effect of yield at Rothamsted and Woburn. Soil degradation. Proc. seminar, Wageningen, 1980187-202.

Slevin ML, Piall EM, Aherne GW, Johnston A, Lister TA(1982). The pharmacokinetics of cytosine arabinoside in the plasma and cerebrospinal fluid during conventional and high‐dose therapy. Medical and Pediatric Oncology vol. 10, (1 S) 157-168.

Cole SCJ, Flanagan RJ, Johnston A, Holt DW(1981). Rapid high-performance liquid chromatographic method for the measurement of verapamil and norverapamil in blood plasma or serum. Journal of Chromatography A vol. 218, (C) 621-629.

Sharma JN, Blackett A, Johnston A, Hathway NR(1981). A single-dose comparison of four slow-release theophylline preparations in normal subjects. Postgraduate Medical Journal vol. 57, (665) 153-155.

Sharma JN, Johnston A, Blackett AN, Hathway NR(1981). Comparative bioavailability of some sustained release theophylline preparations in normal volunteers. British Journal of Clinical Pharmacology vol. 11, (4)

Johnston A, Hamer J(1981). Gas chromatography and enzyme immunoassay compared for analysis of disopyramide in plasma. Clinical Chemistry vol. 27, (2)

Johnston A, Burgess CD, Henry JA(1981). Mexiletine elimination: Influence of urinary pH and volume. British Journal of Pharmacology vol. 72, (1)

Lewis AM, Johnston A, Patel L, Turner P(1981). Mexiletine in human blood and breast milk. Postgraduate Medical Journal vol. 57, (671) 546-547.

Slevin ML, Piall EM, Aherne GW, Johnston A, Sweatman MC, Lister TA(1981). Pharmacokinetics of subcutaneous cytosine arabinoside in patients with acute myeloblastic leukaemia. British Journal of Cancer vol. 44, (2)

Johnston A, Culig J, Turner P(1981). Salivary and urine theophylline levels in management of childhood asthma. Journal of the Royal Society of Medicine vol. 74, (10) 776-777.

Mudhiddin KA, Johnston A(1981). Spectrofluorimetric assay and buccal absorption of flecainide (R-818). British Journal of Clinical Pharmacology vol. 12, (2)

Johnston A, Burgess C, Hamer J(1981). Systemic availability of oral verapamil and effect on PR interval in man. British Journal of Clinical Pharmacology vol. 12, (3) 397-400.

Slevin M, Piall E, Aherne G, Johnston A, Sweatman M, Lister T(1981). The pharmacokinetics of subcutaneous cytosine arabinoside in patients with acute myelogenous leukaemia. British Journal of Clinical Pharmacology vol. 12, (4) 507-510.

Cooke ED, Johnston A(1980). Gas-powered jet injection compared with conventional methods of injection using lignocaine and technetium-99m. British Medical Journal vol. 281, (6241) 643-644.

Johnston A, Henry J, Warrington S, Hamer N(1980). Pharmacokinetics of oral disopyramide phosphate in patients with renal impairment. British Journal of Clinical Pharmacology vol. 10, (3) 245-248.

Johnston A, Warrington SJ, Turner P(1979). TIQUINAMIDE. The Lancet vol. 314, (8153)

Davis BJ, Johnston A(1979). Buccal absorption of verapamil - evidence for membrane storage. British Journal of Clinical Pharmacology vol. 7, (4)

Henry J, Johnston A, Warrington S, Hamer N (1979). Influence of renal failure on disopyramide pharmacokinetics [proceedings]. British Journal of Clinical Pharmacology. vol. 7, 427P-428P.

Burgess C, Hamer J, Johnston A(1979). Pharmacodynamic studies of verapamil after oral and i.v. administration in man [proceedings]. British Journal of Clinical Pharmacology vol. 8, (4) 397P-398P.

Johnston A, Burgess C, Warrington S, Wadsworth J, Hamer N(1979). The effect of spontaneous changes in urinary pH on mexiletine plasma concentrations and excretion during chronic administration to healthy volunteers. British Journal of Clinical Pharmacology vol. 8, (4) 349-352.

Jain S, Johnston A(1979). The measurement of lignocaine at low concentrations in plasma, a comparison of gas liquid chromatography with enzyme immunoassay. British Journal of Clinical Pharmacology vol. 8, (6) 598-599.

Johnston A, McHaffie D(1978). Gas-liquid chromatographic method for the routine estimation of disopyramide in plasma or serum. Journal of Chromatography A vol. 152, (2) 501-506.

Beckett A, Burgess C, Johnston A, Warrington S(1978). The systemic availability of a slow release rectal preparation of lignocaine [proceedings]. British Journal of Clinical Pharmacology vol. 6, (5) 442P-443P.

Mchaffie DJ, Guz A, Johnston A(1977). IMPOTENCE IN PATIENT ON DISOPYRAMIDE. The Lancet vol. 309, (8016)