Publications:  Prof Peter Heathcote

Yokoyama K, Lord JS, Murahari P, Wang K, Dunstan D, Waller SP, McPhail DJ, Hillier AD et al.(2016). The new high field photoexcitation muon spectrometer at the ISIS pulsed neutron and muon source. Review of Scientific Instruments

DREW AJ, wang K, Murahari P, Yokoyama, Misquitta, Dunstan, Heathcote(2016). Temporal mapping of photochemical reactions and molecular excited states with carbon specificity. Nature Materials

Yokoyama K, Murahari P, Heathcote P, Nuccio L, Lord JS, Morley NA, Drew AJ(2013). Future directions of mu SR-laser excitation. PHYSICA SCRIPTA vol. 88, (6) Article ARTN 068511,

Berthold T, von Gromoff ED, Santabarbara S, Stehle P, Link G, Poluektov OG, Heathcote P, Beck CF et al.(2012). Exploring the Electron Transfer Pathways in Photosystem I by High-Time-Resolution Electron Paramagnetic Resonance: Observation of the B-Side Radical Pair P(700)(+)A(1B)(-) in Whole Cells of the Deuterated Green Alga Chlamydomonas reinhardtii at Cryogenic Temperatures. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY vol. 134, (12) 5563-5576.

Holden-Dye K, Crouch LI, Williams CM, Bone RA, Cheng JD, Bohles F, Heathcote P, Jones MR(2011). Opposing structural changes in two symmetrical polypeptides bring about opposing changes to the thermal stability of a complex integral membrane protein. ARCH BIOCHEM BIOPHYS vol. 505, (2) 160-170.

Marinoni I, Nonnis S, Monteferrante C, Heathcote P, Hartig E, Bottger LH, Trautwein AX, Negri A et al.(2008). Characterization of L-aspartate oxidase and quinolinate synthase from Bacillus subtilis. FEBS J vol. 275, (20) 5090-5107.

Brocker MJ, Virus S, Ganskow S, Heathcote P, Heinz DW, Schubert WD, Jahn D, Moser J(2008). ATP-driven reduction by dark-operative protochlorophyllide oxidoreductase from Chlorobium tepidum mechanistically resembles nitrogenase catalysis. J BIOL CHEM vol. 283, (16) 10559-10567.

Moore AL, Carre JE, Affourtit C, Albury MS, Crichton PG, Kita K, Heathcote P(2008). Compelling EPR evidence that the alternative oxidase is a diiron carboxylate protein. BBA-BIOENERGETICS vol. 1777, (4) 327-330.

Heathcote P, Nugent J(2008). Michael Charles Whitmore Evans (September 24, 1940 february 21, 2007). PHOTOSYNTH RES vol. 96, (1) 1-4.

Frank S, Deery E, Brindley AA, Leech HK, Lawrence A, Heathcote P, Schubert HL, Brocklehurst K et al.(2007). Elucidation of substrate specificity in the cobalamin (vitamin B-12) biosynthetic methyltransferases - Structure and function of the C20 methyltransferase (Cbil) from methanothermobacter thermautotrophicus. J BIOL CHEM vol. 282, (33) 23957-23969.

Santabarbara S, Agostini G, Casazza AP, Syme CD, Heathcote P, Bohles F, Evans MCW, Jennings RC et al.(2007). Chlorophyll triplet states associated with Photosystem I and Photosystem II in thylakoids of the green alga Chlamydomonas reinhardtii. BBA-BIOENERGETICS vol. 1767, (1) 88-105.

Santabarbara S, Bombelli P, Purton S, Russell C, Casazza A, Evans M, Heathcote P(2007). The physiological relevance of electron transfer involving redox-active centres bound to the PsaA and PsaB subunits of Photosystem I. PHOTOSYNTHESIS RESEARCH vol. 91, (2-3) 155-156.

Ali K, Santabarbara S, Heathcote P, Evans MCW, Purton S(2006). Bidirectional electron transfer in photosystem I: Replacement of the symmetry-breaking tryptophan close to the PsaB-bound phylloquinone (A(1B))with a glycine residue alters the redox properties of A(1B) and blocks forward electron transfer at cryogenic temperatures. BBA-BIOENERGETICS vol. 1757, (12) 1623-1633.

Byrdin M, Santabarbara S, Gu FF, Fairclough WV, Heathcote P, Redding K, Rappaport F(2006). Assignment of a kinetic component to electron transfer between iron-sulfur clusters F-X and F-A/B of Photosystem I. BBA-BIOENERGETICS vol. 1757, (11) 1529-1538.

Heyes DJ, Heathcote P, Rigby SEJ, Palacios MA, van Grondelle R, Hunter CN(2006). The first catalytic step of the light-driven enzyme protochlorophyllide oxidoreductase proceeds via a charge transfer complex. J BIOL CHEM vol. 281, (37) 26847-26853.

Santabarbara S, Kuprov I, Hore PJ, Casal A, Heathcote P, Evans MCW(2006). Analysis of the spin-polarized electron spin echo of the [P(700)(+)A(1)(-)] radical pair of photosystem I indicates that both reaction center Subunits are competent in electron transfer in cyanobacteria, green algae, and higher plants. BIOCHEMISTRY-US vol. 45, (23) 7389-7403.

Layer G, Pierik AJ, Trost M, Rigby SE, Leech HK, Grage K, Breckau D, Astner I et al.(2006). The substrate radical of Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN. J BIOL CHEM vol. 281, (23) 15727-15734.

Reents H, Gruner I, Harmening U, Bottger LH, Layer G, Heathcote P, Trautwein AX, Jahn D et al.(2006). Bacillus subtilis Fnr senses oxygen via a [4Fe-4S] cluster coordinated by three cysteine residues without change in the oligomeric state. MOL MICROBIOL vol. 60, (6) 1432-1445.

Hughes AV, Rees P, Heathcote P, Jones MR(2006). Kinetic analysis of the thermal stability of the photosynthetic reaction center from Rhodobacter sphaeroides. BIOPHYS J vol. 90, (11) 4155-4166.

Santabarbara S, Agostini G, Heathcote P, Carbonera D(2005). A fluorescence detected magnetic resonance investigation of the carotenoid triplet states associated with photosystem II of isolated spinach thylakoid membranes. Photosynth Res vol. 86, (1-2) 283-296.

Watson AJ, Hughes AV, Fyfe PK, Wakeham MC, Holden-Dye K, Heathcote P, Jones MR (2005). On the role of basic residues in adapting the reaction centre - LH1 complex for growth at elevated temperatures in purple bacteria. PHOTOSYNTHESIS RESEARCH. vol. 86, 81-100.

Layer G, Grage K, Teschner T, Schunemann V, Breckau D, Masoumi A, Jahn M, Heathcote P et al.(2005). Radical S-adenosylmethionine enzyme coproporphyrinogen III oxidase HemN - Functional features of the [4Fe-4S] cluster and the two bound S-adenosyl-L-methionines. J BIOL CHEM vol. 280, (32) 29038-29046.

Heldt D, Lawrence AD, Lindenmeyer M, Deery E, Heathcote P, Rigby SE, Warren MJ (2005). Aerobic synthesis of vitamin B12: ring contraction and cobalt chelation. Biochem Soc Trans. vol. 33, 815-819.

Frank S, Brindley AA, Deery E, Heathcote P, Lawrence AD, Leech HK, Pickersgill RW, Warren MJ(2005). Anaerobic synthesis of vitamin B12: characterization of the early steps in the pathway. Biochem Soc Trans vol. 33, (Pt 4) 811-814.

Santabarbara S, Heathcote P, Evans MCW(2005). Modelling of the electron transfer reactions in Photosystem I by electron tunnelling theory: the phylloquinones bound to the PsaA and the PsaB reaction centre subunits of PS I are almost isoenergetic to the iron-sulfur cluster F(X). Biochim Biophys Acta vol. 1708, (3) 283-310.

Fyfe PK, Hughes AV, Heathcote P, Jones MR(2005). Proteins, chlorophylls and lipids: X-ray analysis of a three-way relationship. TRENDS PLANT SCI vol. 10, (6) 275-282.

Santabarbara S, Kuprov I, Fairclough WV, Purton S, Hore PJ, Heathcote P, Evans MCW(2005). Bidirectional electron transfer in photosystem I: Determination of two distances between P-700(+) and A(1)(-) in spin-correlated radical pairs. BIOCHEMISTRY-US vol. 44, (6) 2119-2128.

Raux-Deery E, Leech HK, Nakrieko K-A, McLean KJ, Munro AW, Heathcote P, Rigby SEJ, Smith AG et al.(2005). Identification and characterization of the terminal enzyme of siroheme biosynthesis from Arabidopsis thaliana: a plastid-located sirohydrochlorin ferrochelatase containing a 2FE-2S center. J Biol Chem vol. 280, (6) 4713-4721.

McGoldrick HM, Roessner CA, Raux E, Lawrence AD, McLean KJ, Munro AW, Santabarbara S, Rigby SEJ et al.(2005). Identification and characterization of a novel vitamin B12 (cobalamin) biosynthetic enzyme (CobZ) from Rhodobacter capsulatus, containing flavin, heme, and Fe-S cofactors. J Biol Chem vol. 280, (2) 1086-1094.

Bratt PJ, Heathcote P, Hassan A, van Tol J, Brunel LC, Schrier J, Angerhofer A(2003). EPR at 24 T of the primary donor radical cation from Blastochloris viridis. CHEM PHYS vol. 294, (3) 277-284.

Rigby SEJ, Muhiuddin IP, Santabarbara S, Evans MCW, Heathcote P(2003). Proton ENDOR spectroscopy of the anion radicals of the chlorophyll primary electron acceptors in type I photosynthetic reaction centres. CHEM PHYS vol. 294, (3) 319-328.

Leech HK, Raux E, McLean KJ, Munro AW, Robinson NJ, Borrelly GPM, Malten M, Jahn D et al.(2003). Characterization of the cobaltochelatase CbiXL: evidence for a 4Fe-4S center housed within an MXCXXC motif. J Biol Chem vol. 278, (43) 41900-41907.

Fairclough WV, Forsyth A, Evans MCW, Rigby SEJ, Purton S, Heathcote P(2003). Bidirectional electron transfer in photosystem I: electron transfer on the PsaA side is not essential for phototrophic growth in Chlamydomonas. BBA-BIOENERGETICS vol. 1606, (1-3) 43-55.

Heathcote P, Jones MR, Fyfe PK (2003). Type I photosynthetic reaction centres: structure and function. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES. vol. 358, 231-243.

Fyfe PK, Jones MR, Heathcote P(2002). Insights into the evolution of the antenna domains of Type-I and Type-II photosynthetic reaction centres through homology modelling. FEBS LETT vol. 530, (1-3) 117-123.

Rigby SEJ, Muhiuddin IP, Evans MCW, Purton S, Heathcote P(2002). Photoaccumulation of the PsaB phyllosemiquinone in Photosystem I of Chlamydomonas reinhardtii. BBA-BIOENERGETICS vol. 1556, (1) 13-20.

McGoldrick H, Deery E, Warren M, Heathcote P (2002). Cobalamin (vitamin B(12)) biosynthesis in Rhodobacter capsulatus. Biochem Soc Trans. vol. 30, 646-648.

Carbonera D, Burzomato V, Bordignon E, Giacometti G, Agostini G, Heathcote P, Leech HK(2002). Fluorescence and absorption detected magnetic resonance of membranes from the green sulfur bacterium Chlorobium limicola. Full assignment of detected triplet states. J PHYS CHEM B vol. 106, (30) 7560-7568.

Leech HK, Raux-Deery E, Heathcote P, Warren MJ (2002). Production of cobalamin and sirohaem in Bacillus megaterium: an investigation into the role of the branchpoint chelatases sirohydrochlorin ferrochelatase (SirB) and sirohydrochlorin cobalt chelatase (CbiX). Biochem Soc Trans. vol. 30, 610-613.

Rich PR, Rigby SEJ, Heathcote P(2002). Radicals associated with the catalytic intermediates of bovine cytochrome c oxidase. BBA-BIOENERGETICS vol. 1554, (3) 137-146.

Heathcote P, Fyfe PK, Jones MR(2002). Reaction centres: the structure and evolution of biological solar power. TRENDS BIOCHEM SCI vol. 27, (2) 79-87.

Fairclough WV, Evans MCW, Purton S, Rigby SEJ, HEATHCOTE P (2002). Site-directed mutagenesis of PsaA:M684 in Chlamydomonas reinhardtii. Conference: PS2001 Proceedings: 12th International Congress on Photosynthesis. (CSIRO Publishing: Melbourne, Australia) from: 18/08/2001 to: 23/08/2001,

Rigby SEJ, Evans MCW, Heathcote P(2001). Electron nuclear double resonance (ENDOR) spectroscopy of radicals in photosystem I and related Type 1 photosynthetic reaction centres. BBA-BIOENERGETICS vol. 1507, (1-3) 247-259.

Heathcote P(2001). Type I photosynthetic reaction centres. Biochim Biophys Acta vol. 1507, (1-3) 1-2.

Muhiuddin IP, Heathcote P, Carter S, Purton S, Rigby SEJ, Evans MCW(2001). Evidence from time resolved studies of the P700(center dot+)/A(1)(center dot-)radical pair for photosynthetic electron transfer on both the PsaA and PsaB branches of the photosystem I reaction centre. FEBS LETT vol. 503, (1) 56-60.

HEATHCOTE P, Muhiuddin IP, Rigby SEJ, Carter S, Purton S, Gu F, Redding K, Evans MCW (2001). Evidence for two functional phylloquinones in Photosystem I from Chlamydomonas reinhardtii. PS2001 proceedings 12th International Congress on Photosynthesis. Conference: 12th International Congress on Photosynthesis. (Brisbane Convention & Exhibition Centre, Queensland, Australia) from: 18/08/2001 to: 23/08/2001,

Purton S, Stevens DR, Muhiuddin IP, Evans MCW, Carter S, Rigby SEJ, Heathcote P(2001). Site-directed mutagenesis of PsaA residue W693 affects phylloquinone binding and function in the photosystem I reaction center of Chlamydomonas reinhardtii. BIOCHEMISTRY-US vol. 40, (7) 2167-2175.