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Publications:  Prof David Griffiths

Awais RO, Duncanson P, Mills B, Luckett JC, Griffiths DV, Hill P, Williams P, Perkins AC (2014). Tc-99m and In-111 labelled benzyl pyrimidine derivatives for targeting SNAP or CLIP protein sites on a genetically modified Gram positive bacterium. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. vol. 41, S431-S431.
Mills B, Luckett J, Awais R, Duncanson P, Griffiths D, Perkins A, Williams P, Hill P (2014). Validation and applications for SNAP-tag imaging of bacterial infection. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. vol. 41, S639-S639.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6967
Awais R, Mills B, Luckett J, Williams P, Hill P, Perkins A, Duncanson P, Griffiths V(2014). Tc-99m-labelling of surface localised SNAP-tag sites on a Gram positive bacterium. NUCLEAR MEDICINE AND BIOLOGY vol. 41, (7) 615-615.
10.1016/j.nucmedbio.2014.05.046
Griffiths DV, Benoit DM, Cheong Y-K, Duncanson P, Han X(2014). Novel Ylidic Phosphoryl Compounds from Halogenated Furan-2,5-Diones with Trivalent Phosphorus Esters: Application of this Approach to New Trisphosphonates Containing a Geminal Bisphosphonate Unit. Phosphorus, Sulfur and Silicon and the Related Elements
10.1080/10426507.2014.905570
Vaughan Griffiths D, Benoit DM, Cheong YK, Duncanson P, Han X(2014). Novel ylidic phosphoryl compounds from halogenated furan-2,5-diones with trivalent phosphorus esters: Application of this approach to new trisphosphonates containing a geminal bisphosphonate unit. Phosphorus, Sulfur and Silicon and the Related Elements vol. 189, 1013-1027.
10.1080/10426507.2014.905570
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6933
Awais RO, Mills B, Luckett JCA, Duncanson P, Griffiths V, Williams P, Hill P, Perkins AC (2013). Radiosynthesis of 99mTc-HYNIC-NH-BG: A new Tc-99m radiotracer to visualise specific cells in vivo via SNAP-tag. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. vol. 40, S129-S129.
Mills B, Steele V, Luckett JCA, Awais RO, Duncanson P, Griffiths V, Cockayne A, Xu M et al. (2013). Surface displayed SNAP-tag as a novel tool for study of Grampositive bacterial infections. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. vol. 40, S178-S178.
Duncanson P, Cheong YK, Motevalli M, Griffiths DV(2012). A novel approach to isoindolo[2,1-a]indol-6-ones. Org Biomol Chem vol. 10, (21) 4266-4279.
10.1039/c2ob25314c
GRIFFITHS D, Cheong Y-K, Duncanson P, Motevalli M(2011). Studies of the reactions of tripodal pyridine-containing ligands with Re(CO)5Br leading to rheniumtricarbonyl complexes with potential biomedical applications. Dalton Transactions vol. 40, (39) 10215-10228.
10.1039/C1DT11020A
Cheong Y-K, Duncanson P, Griffiths DV, Motevalli M (2010). The impact of ligand structure on the rheniumtricarbonyl complexes from tripodal pyridine-containing chelators. Nuclear Medicine and Biology. Conference: International symposium on Technetium and Other Radiometals in Chemistry and Medicine (Bressanone, Italy) from: 08/09/2010 to: 11/09/2010, vol. 37, 677-678.
10.1016/j.nucmedbio.2010.04.079
Cheong Y-K, Duncanson P, Griffiths DV (2010). Isoindolo[2,1a]indol-6-one formation via the reaction of a phthaloylamino-substituted benzoylphosphonates with trialkyl phosphites involving phosphonate group migration and β-ketophosphonate formation. Book of Abstracts. Conference: 18th International Conference on Phosphorus Chemistry (Wroclaw, Poland) from: 11/07/2010 to: 15/07/2010, 164-164.
Cheong Y-K, Duncanson P, Griffiths DV, Awais RO (2010). Novel products from the reactions of nitro-substituted benzoylphosphonates with trialkyl phosphites including the formation of reactive ylidic-phosphates. Book of Abstracts. Conference: 18th International Conference on Phosphorus Chemistry (Wroclaw, Poland) from: 11/07/2010 to: 15/07/2010, 158-158.
GRIFFITHS D, Al-Jeboori MJ, Arnold PJ, Cheong Y-K, Duncanson P, Motevalli M(2010). Studies of rheniumtricarbonyl complexes of tripodal pyridyl-based ligands. Inorganica Chimica Acta vol. 363, 1186-1194.
10.1016/j.ica.2009.11.039
Cheong Y-K, Duncanson P, Griffiths DV, Motevalli M (2010). The impact of ligand structure on the rheniumtricarbonyl complexes from tripodal pyridine-containing chelators. Technetium and Other Radiometals in Chemistry and Medicine. Editors: Mazzi, U, Eckelman, WC, Conference: International symposium on Technetium and Other Radiometals in Chemistry and Medicine (Bressanone, Italy) from: 08/09/2010 to: 11/09/2010, 37-40.
Griffiths DV, Cheong Y-K, Duncanson P, Taylor HV (2009). Novel products from the reactions of aroyl chlorides with trialkyl phosphites. Book of Abstracts. Conference: IIIrd Aminophosphorus and Phosphapeptide Meeting (Vitoria-Gasteiz, Spain) from: 17/09/2009 to: 18/09/2009, 10-10.
Cheong YK, Duncanson P, Griffiths DV(2008). Cyclisation reactions of 2-substituted benzoylphosphonates with trialkyl phosphites via nucleophilic attack on a carbonyl-containing ortho substituent. TETRAHEDRON vol. 64, (10) 2329-2338.
10.1016/j.tet.2008.01.012
Griffiths DV, Al-Jeboori MJ, Cheong Y-K, Duncanson P, Harris JE, Salt MC, Taylor HV(2008). Electron-rich heteroaroylphosphonates and their reaction with trimethyl phosphite. Org Biomol Chem vol. 6, (3) 577-585.
10.1039/b717130g
Griffiths DV, Groombridge HJ, Salt MC (2008). Investigations into the oxidative stability of hydroxymethyl- and bis(hydroxymethyl)-phosphines. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS. vol. 183, 473-478.
10.1080/10426500701761417
Cheong Y-K, Duncanson P, Han X (2008). Synthesis and reactions of phosphorylated maleimides. Conference: 15th International conferences on Chemistry of Phosphorus compounds (St Petersburg, Russia) from: 25/05/2008 to: 30/05/2008, 128-128.
Cheong Y-K, Duncanson P (2008). The reaction of trivalent phosphorus compounds with halogenated pyrrole- and furan-2,5-diones. Conference: 15th International conferences on Chemistry of Phosphorus compounds (St Petersburg, Russia) from: 25/05/2008 to: 30/05/2010, 124-124.
GRIFFITHS DV, Groombridge HJ, Salt MC (2006). Investigations into the Inherent Oxidative Stability of the Hydroxymethylphosphine Centre in Chelates for 99mTc-Based Radiopharmaceuticals. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine. Conference: 7th International Symposium on Technetium , Rhenium and Other Metals in Chemistry and Nuclear Medicine (Bresannone, Italy) from: 05/09/2006 to: 09/09/2006, vol. 7, 163-164.
GRIFFITHS DV, Groombridge HJ, Motevalli M, Salt MC (2006). Nucleophilic Addition to Vinyl- and Divinyl-Phosphine Sulfides as a Convenient Approach for the Synthesis of Phosphine-Containing Chelates for Rhenium and Technetium. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine. Editors: Mazzi, U, Conference: 7th International Symposium on Technetium , Rhenium and Other Metals in Chemistry and Nuclear Medicine (Bresannone, Italy) from: 05/09/2006 to: 09/09/2006, vol. 7, 105-106.
GRIFFITHS DV, Duncanson P, Bhalla R, Iveson PB, Powell NA, O'Shea D, Wadsworth H (2006). Synthesis of Bifunctional Tetraamine Chelates. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine. Conference: 7th International Symposium on Technetium , Rhenium and Other Metals in Chemistry and Nuclear Medicine (Bresannone, Italy) from: 05/09/2006 to: 09/09/2006, vol. 7, 161-162.
GRIFFITHS DV, Duncanson P, Arnold PJ, Motevalli M, Bhalla R (2006). Tris-Pyridyl Chelates for the Preparation of Lipophilic Cationic Complexes with Potential Radiopharmaceutical Applications. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine. Conference: 7th International Symposium on Technetium , Rhenium and Other Metals in Chemistry and Nuclear Medicine (Bresannone, Italy) from: 05/09/2006 to: 09/09/2006, vol. 7, 165-166.
Phillips MJ, Duncanson P, Darr JA, Wilson K, GRIFFITHS DV, Rehman I(2005). Surface modification of bioceramics by grafting of tailored allyl phosphonic acid. Advances in Applied Ceramics vol. 104, (5) 261-267.
10.1179/174367605X62436
Griffiths DV, Groornbridge HJ, Mahoney PM, Swetnam SP, Walton G, York DC(2005). Nucleophilic addition to dimethylvinylphosphine sulfide as a convenient route to polydentate ligands containing the 2-dimethylphosphinoethyl unit. TETRAHEDRON vol. 61, (19) 4595-4600.
10.1016/j.tet.2005.03.012
GRIFFITHS DV, Cheong Y-K, Imirniyaz T, Duncanson P, Salt MJ (2004). Cyclisation reaction of aroylphosphonates with trialkyl phosphites via anionic intermediates. Conference: ICPC2004, Birmingham International Conference Centre, July 2004.
GRIFFITHS DV, Duncanson P (2004). Novel ylides from the reaction of halogeno-substituted furan-2,5-diones with trivalent phosphorus compounds. Conference: ICPC2004, Birmingham International Conference Centre, July 2004.
GRIFFITHS DV, Groombridge HJ (2004). Nucleophilic addition to dimethylvinylphosphine sulfide as a convenient route to polydentate ligands containing the 2-dimethylphosphinoethyl unit. Conference: ICPC2004, Birmingham International Conference Centre, July 2004
10.1016/j.tet.2005.03.012
GRIFFITHS DV, Taylor HV, Salt M (2004). The reaction of heteroaroylphosphonates with trialkyl phosphites. Conference: ICPC2004, Birmingham International Conference Centre, July 2004
Arnold PJ, Davies SC, Durrant MC, Griffiths DV, Hughes DL, Sharpe PC(2003). Copper(II) nitrite complexes of tripodal ligands derived from 1,1,1-tris(2-pyridyl)methylamine. INORG CHIM ACTA vol. 348, 143-149.
10.1016/S0020-1693(02)01487-1
Griffiths DV, Duncanson P (2002). The reactions of trialkylsilyl-containing phosphites with electrophilic organic compounds. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS. vol. 177, 2213-2214.
10.1080/10426500290095458
Scheuermann JEW, Ilyashenko G, Griffiths DV, WATKINSON M(2002). Solvent-mediated selective single and double ring-opening of N-tosyl-activated aziridines using benzylamine. Tetrahedron Asymmetry vol. 13, (3) 269-272.
10.1016/S0957-4166(02)00102-7
GRIFFITHS DV, Mahoney PM, Higley B, Caesar JC, Burke JF, Tonkinson DJ (2002). Synthesis and Biodistribution Studies of the 99mTechnetium Oxo-Complexes of a Series of Substituted Bis(aminoethanethiol) Ligands incorporating N-Alkylated-piperidin-4-yl Ring Systems. Editors: Nicolini, M, Mazzi, U, 535-537.
Scheuermann JEW, Ronketti F, Motevalli M, Griffiths DV, Watkinson M(2002). The synthesis of C-2-symmetric 1,4,7-triazacyclononane ligands derived from chiral aziridines. NEW J CHEM vol. 26, (8) 1054-1059.
10.1039/b204818c
Gibson AM, Mendizabal M, Pither R, Pullan SE, Griffiths V, Duncanson P (2001). Radiolabelled bisphosphonates and method. no. PCT/EP00/07490,
Arnold PJ, Davies SC, Dilworth JR, Durrant MC, Griffiths DV, Hughes DL, Richards RL, Sharpe PC(2001). Copper complexes of the functionalised tripodal ligand tris(2-pyridyl)methylamine and its derivatives. J CHEM SOC DALTON (5) 736-746.
10.1039/b008476j
Dilworth JR, Zheng Y, Griffiths DV(1999). Binuclear complexes with ligands based on the 2,6-bis(diphenylphosphinomethyl)benzene framework. Syntheses and crystal structures of [Ir<inf>2</inf>Cl<inf>2</inf>(μ-CO){2,6-(Ph<inf>2</inf>PH<inf>2</inf>) <inf>2</inf>C<inf>6</inf>H<inf>3</inf>S}<inf>2</inf>]·2CH <inf>2</inf>Cl<inf>2</inf>, [Ni<inf>2</inf>{2,6-(Ph<inf>2</inf>PCH<inf>2</inf>)<inf>2</inf>C <inf>6</inf>H<inf>4</inf>S} ... Journal of the Chemical Society - Dalton Transactions (11) 1877-1881.
10.1039/a901291e
Ahmed LS, Clegg W, Davies DA, Dilworth JR, Elsegood MRJ, Griffiths DV, Horsburgh L, Miller JR et al.(1998). The preparation and coordination chemistry of substituted benzenethiols. Triphenylphosphine gold(I) complexes of sterically demanding and nondemanding arenethiols. The absence of gold(I)-gold(I) interactions. Polyhedron vol. 18, (3-4) 593-600.
10.1016/S0277-5387(98)00339-8
Davies HO, Dilworth JR, Griffiths DV, Miller JR, Zheng Y(1998). The synthesis and crystal structures of the amide NS<inf>3</inf> macrocycle L<inf>1</inf>, and the silver complexes [Ag(L<inf>1</inf>)] <inf>n</inf>[CF<inf>3</inf>so<inf>3</inf>]<inf>n</inf> and of [Ag(L<inf>2</inf>)] <inf>2</inf>[CF<inf>3</inf>so<inf>3</inf>]<inf>2</inf> (see abstract). Polyhedron vol. 18, (3-4) 459-467.
10.1016/S0277-5387(98)00318-0
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