Publications:  Prof Joost de Bruijn

Holthof LC, Van Der Horst HJ, Van Hal-Van Veen SE, Ruiter RWJ, Li F, Buijze M, Andersen MN, Yuan H et al.(2020). Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma. Haematologica vol. 105, (2) E80-E83.

Li M, Guo X, Qi W, Wu Z, de Bruijn JD, Xiao Y, Bao C, Yuan H(2020). Macrophage polarization plays roles in bone formation instructed by calcium phosphate ceramics. Journal of Materials Chemistry B

van Dijk LA, Barrère-de Groot F, Rosenberg AJWP, Pelletier M, Christou C, de Bruijn JD, Walsh WR(2020). MagnetOs, Vitoss, and Novabone in a Multi-endpoint Study of Posterolateral Fusion: A True Fusion or Not?. Clinical Spine Surgery

Westhrin M, Holien T, Zahoor M, Moen SH, Buene G, Størdal B, Hella H, Yuan H et al.(2019). Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone. JBMR Plus vol. 4, (1) e10247-e10247.

Das R, Roosloot R, van Pel M, Schepers K, Driessen M, Fibbe WE, de Bruijn JD, Roelofs H(2019). Preparing for cell culture scale-out: establishing parity of bioreactor- and flask-expanded mesenchymal stromal cell cultures. J Transl Med vol. 17, (1) 241-241.

Drent E, Poels R, Ruiter R, van de Donk NWCJ, Zweegman S, Yuan H, de Bruijn J, Sadelain M et al.(2019). Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor-engineered T Cells. Clin Cancer Res vol. 25, (13) 4014-4025.

Naik J, Themeli M, de Jong-Korlaar R, Ruiter RWJ, Poddighe PJ, Yuan H, de Bruijn JD, Ossenkoppele GJ et al.(2019). CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia. Haematologica vol. 104, (3) e100-e103.

Duan R, van Dijk LA, Barbieri D, de Groot F, Yuan H, de Bruijn JD(2019). Accelerated bone formation by biphasic calcium phosphate with a novel sub-micron surface topography. Eur Cell Mater vol. 37, 60-73.

van Dijk LA, Barbieri D, Barrère-de Groot F, Yuan H, Oliver R, Christou C, Walsh WR, de Bruijn JD(2019). Efficacy of a synthetic calcium phosphate with submicron surface topography as autograft extender in lapine posterolateral spinal fusion. J Biomed Mater Res B Appl Biomater

Holien T, Westhrin M, Moen SH, Zahoor M, Buene G, Stordal B, Hella H, Yuan H et al. (2018). BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone. BLOOD. vol. 132,

van Dijk LA, Duan R, Luo X, Barbieri D, Pelletier M, Christou C, Rosenberg AJWP, Yuan H et al.(2018). Biphasic calcium phosphate with submicron surface topography in an Ovine model of instrumented posterolateral spinal fusion. JOR Spine vol. 1, (4) e1039-e1039.

Duan R, Barbieri D, De Groot F, De Bruijn JD, Yuan H(2018). Modulating Bone Regeneration in Rabbit Condyle Defects with Three Surface-Structured Tricalcium Phosphate Ceramics. ACS Biomaterials Science and Engineering vol. 4, (9) 3347-3355.

Das R, Roosloot R, Driessen M, Tra W, Burer S, de Bruijn J (2018). A SINGLE-STEP EXPANSION SYSTEM FOR LARGE-FOLD EXPANSION OF BONE MARROW-DERIVED MSCS. CYTOTHERAPY. vol. 20, S34-S34.

Tra W, Prange J, Burer S, Mohr D, Das R, de Bruijn J (2018). MICROCARRIER CULTURE OF MUSCLE PRECURSOR CELLS FOR CLINICAL APPLICATION. CYTOTHERAPY. vol. 20, S90-S91.

Driessen M, Roosloot R, Tra W, Das R, de Bruijn J (2018). SINGLE-STEP EXPANSION OF ADIPOSE-DERIVED STEM CELLS WITH PLATELET LYSATE IN SCINUS BIOREACTOR. CYTOTHERAPY. vol. 20, S34-S35.

Barrère-De Groot F, Yuan H, De Bruijn JD (2018). Clinical relevance of sub-micron textured calcium phosphates for bone tissue regeneration. Materials Today: Proceedings. vol. 5, 15501-15505.

Carretta M, de Boer B, Jaques J, Antonelli A, Horton SJ, Yuan H, de Bruijn JD, Groen RWJ et al.(2017). Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models. Experimental Hematology vol. 51, 36-46.

Drent E, Themeli M, Poels R, de Jong-Korlaar R, Yuan H, de Bruijn J, Martens ACM, Zweegman S et al.(2017). A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization. Molecular Therapy vol. 25, (8) 1946-1958.

Tra W, Das R, Roosloot R, Driessen M, van Santen P, de Bruijn J (2017). CULTURE OF ADIPOSE-DERIVED STEM CELLS USING CLOSED BIOREACTOR TECHNOLOGY. CYTOTHERAPY. vol. 19, S51-S52.

Zhang J, Dalbay M, Luo X, Vrij E, Barbieri D, Moroni L, de Bruijn JD, van Blitterswijk CA et al.(2017). Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis. Acta Biomaterialia

Barbieri D, Yuan H, Ismailo¿lu AS, de Bruijn JD(2017). * Comparison of Two Moldable Calcium Phosphate-Based Bone Graft Materials in a Noninstrumented Canine Interspinous Implantation Model. Tissue Eng Part A vol. 23, (23-24) 1310-1320.

Zhang J, Sun L, Luo X, Barbieri D, de Bruijn JD, van Blitterswijk CA, Moroni L, Yuan H(2017). Cells responding to surface structure of calcium phosphate ceramics for bone regeneration. J Tissue Eng Regen Med

DE BRUIJN JD(2016). Establishing human leukemia xenograft mouse models by implanting human bone marrow-2 like scaffold-based niches. Blood

de Haart SJ, Holthof L, Noort WA, Minnema MC, Emmelot ME, Aarts-Riemens T, Doshi P, Sasser K et al.(2016). Sepantronium bromide (YM155) improves daratumumab-mediated cellular lysis of multiple myeloma cells by abrogation of bone marrow stromal cell-induced resistance. Haematologica vol. 101, (8) e339-e342.

Das R, Roosloot R, Burer J, Driessen M, Tra W, van Santen P, de Bruijn J(2016). COST-EFFICIENT, CLOSED-SYSTEM MSC CULTURE TO THERAPEUTICALLY RELEVANT QUANTITIES. CYTOTHERAPY vol. 18, (6) S81-S82.

Das R, Roosloot R, Burer J, Zuijderduijn R, Roelofs H, van Santen P, de Bruijn J(2016). ONE-STEP BONE MARROW-DERIVED MSC CULTURE USING NOVEL BIOREACTOR TECHNOLOGY. CYTOTHERAPY vol. 18, (6) S80-S81.

Sontakke P, Carretta M, Jaques J, Brouwers-Vos AZ, Lubbers-Aalders L, Yuan H, de Bruijn JD, Martens ACM et al.(2016). Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model. Leukemia

Drent E, Groen RWJ, Noort WA, Themeli M, van Bueren JJL, Parren PWHI, Kuball J, Sebestyen Z et al.(2016). Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma. Haematologica vol. 101, (5) 616-625.

Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE et al.(2015). International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials. Cytotherapy vol. 18, (2) 151-159.

Tra W, Das R, Driessen M, van Santen P, de Bruijn J(2015). CULTURE OF ADIPOSE-DERIVED STEM CELLS IN A CLOSED BIOREACTOR SYSTEM FOR CELL THERAPY. CYTOTHERAPY vol. 17, (6) S44-S44.

Wang L, Barbieri D, Zhou H, De Bruijn JD, Bao C, Yuan H(2015). Effect of particle size on osteoinductive potential of microstructured biphasic calcium phosphate ceramic. Journal of Biomedical Materials Research - Part A vol. 103, (6) 1919-1929.

Luo X, Barbieri D, Passanisi G, Yuan H, De Bruijn JD(2015). Influence of fluoride in poly(d, l -lactide)/apatite composites on bone formation. Journal of Biomedical Materials Research - Part B Applied Biomaterials vol. 103, (4) 841-852.

Eglin D, Alini M, de Bruijn J, Gautrot J, Grijpma DW, Kamer L, Lai Y, Lu S et al.(2015). The RAPIDOS project-European and Chinese collaborative research on biomaterials. J Orthop Translat vol. 3, (2) 78-84.

Zhang J, Barbieri D, Ten Hoopen H, De Bruijn JD, Van Blitterswijk CA, Yuan H(2015). Microporous calcium phosphate ceramics driving osteogenesis through surface architecture. Journal of Biomedical Materials Research - Part A vol. 103, (3) 1188-1199.

Davison NL, Su J, Yuan H, van den Beucken JJJP, de Bruijn JD, de Groot FB(2015). Influence of surface microstructure and chemistry on osteoinduction and osteoclastogenesis by biphasic calcium phosphate discs. European Cells and Materials vol. 29, 314-329.

Zhang J, Luo X, Barbieri D, Barradas AMC, de Bruijn JD, van Blitterswijk CA, Yuan H(2014). The size of surface microstructures as an osteogenic factor in calcium phosphate ceramics. Acta Biomater vol. 10, (7) 3254-3263.

Davison NL, Luo X, Schoenmaker T, Everts V, Yuan H, Barrère-de Groot F, de Bruijn JD(2014). Submicron-scale surface architecture of tricalcium phosphate directs osteogenesis in vitro and in vivo. European Cells and Materials vol. 27, 281-297.

Das R, Roosloot R, Tra W, Roelofs H, van Santen P, de Bruijn J(2014). CONTROLLED CULTURE OF ADHERENT CELLS IN A NOVEL, CLOSED BIOREACTOR SYSTEM FOR CELL THERAPY PRODUCTION. CYTOTHERAPY vol. 16, (4) S102-S103.

van Leeuwen AC, Yuan H, Passanisi G, van der Meer JW, de Bruijn JD, van Kooten TG, Grijpma DW, Bos RRM(2014). Poly(trimethylene carbonate) and biphasic calcium phosphate composites for orbital floor reconstruction: A feasibility study in sheep. European Cells and Materials vol. 27, 81-97.

Wang L, Barbieri D, Zhou H, de Bruijn JD, Bao C, Yuan H(2014). Effect of particle size on osteoinductive potential of microstructured biphasic calcium phosphate ceramic. Journal of Biomedical Materials Research - Part A

Davison NL, Gamblin AL, Layrolle P, Yuan H, de Bruijn JD, Barrère-de Groot F(2014). Liposomal clodronate inhibition of osteoclastogenesis and osteoinduction by submicrostructured beta-tricalcium phosphate. Biomaterials vol. 35, (19) 5088-5097.

Zhang J, Barbieri D, ten Hoopen H, de Bruijn JD, van Blitterswijk CA, Yuan H(2014). Microporous calcium phosphate ceramics driving osteogenesis through surface architecture. Journal of Biomedical Materials Research - Part A

Davison NL, ten Harkel B, Schoenmaker T, Luo X, Yuan H, Everts V, Barrère-de Groot F, de Bruijn JD(2014). Osteoclast resorption of beta-tricalcium phosphate controlled by surface architecture. Biomaterials vol. 35, (26) 7441-7451.

van Leeuwen AC, Yuan H, Passanisi G, van der Meer JW, de Bruijn JD, van Kooten TG, Grijpma DW, Bos RRM(2014). Poly(trimethylene carbonate) and biphasic calcium phosphate composites for orbital floor reconstruction: A feasibility study in sheep. European Cells and Materials vol. 27, 81-97.

Eniwumide JO, Tanaka M, Nagai N, Morita Y, de Bruijn J, Yamamoto S, Onodera S, Kondo E et al.(2014). The morphology and functions of articular chondrocytes on a honeycomb-patterned surface. Biomed Res Int vol. 2014,

Luo X, Barbieri D, Davison N, Yan Y, De Bruijn JD, Yuan H(2014). Zinc in calcium phosphate mediates bone induction: In vitro and in vivo model. Acta Biomaterialia vol. 10, (1) 477-485.

Barbieri D, Yuan H, Luo X, Farè S, Grijpma DW, De Bruijn JD(2013). Influence of polymer molecular weight in osteoinductive composites for bone tissue regeneration. Acta Biomaterialia vol. 9, (12) 9401-9413.

Delawi D, Kruyt MC, Huipin Y, Vincken KL, De Bruijn JD, Oner FC, Dhert WJA(2013). Comparing autograft, allograft, and tricalcium phosphate ceramic in a goat instrumented posterolateral fusion model. Tissue Engineering - Part C: Methods vol. 19, (11) 821-828.

Barbieri D, de Bruijn JD, Luo X, Farè S, Grijpma DW, Yuan H(2013). Controlling dynamic mechanical properties and degradation of composites for bone regeneration by means of filler content. Journal of the Mechanical Behavior of Biomedical Materials vol. 20, 162-172.

Pattappa G, Thorpe SD, Jegard NC, Heywood HK, de Bruijn JD, Lee DA(2013). Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells. Tissue Eng Part C Methods vol. 19, (1) 68-79.

Barbieri D, Yuan H, Luo X, Farè S, Grijpma DW, de Bruijn JD(2013). Influence of polymer molecular weight in osteoinductive composites for bone tissue regeneration. Acta Biomaterialia

Luo X, Barbieri D, Davison N, Yan Y, de Bruijn JD, Yuan H(2013). Zinc in calcium phosphate mediates bone induction: In vitro and in vivo model. Acta Biomaterialia

Groen RWJ, Noort WA, Raymakers RA, Prins HJ, Aalders L, Hofhuis FM, Moerer P, Van Velzen JF et al.(2012). Reconstructing the human hematopoietic niche in immunodeficient mice: Opportunities for studying primary multiple myeloma. Blood vol. 120, (3)

Noort W, Groen R, Raymakers R, Prins H, Aalders L, Hofhuis F, van Kessel B, Moerer P et al. (2012). TOWARDS PERSONALIZED MEDICINE USING A NOVEL PRECLINICAL MODEL: IDENTIFYING DARATUMUMAB AS EFFECTIVE TREATMENT FOR MULTIPLE MYELOMA. HAEMATOLOGICA. vol. 97, 438-438.

Davison N, Yuan H, de Bruijn JD, Barrere-de Groot F(2012). In vivo performance of microstructured calcium phosphate formulated in novel water-free carriers. ACTA BIOMATERIALIA vol. 8, (7) 2759-2769.

Higuera GA, Schop D, Spitters TWGM, van Dijkhuizen-Radersma R, Bracke M, de Bruijn JD, Martens D, Karperien M et al.(2012). Patterns of Amino Acid Metabolism by Proliferating Human Mesenchymal Stem Cells. TISSUE ENGINEERING PART A vol. 18, (5-6) 654-664.

Barbieri D, Altomare L, Xu Q, Farè S, Grijpma DW, De Bruijn JD, Yuan H(2011). Load-bearing composite for bone regeneration. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials

de Ruiter A, Meijer G, Dormaar T, Janssen N, van der Bilt A, Slootweg P, de Bruijn J, van Rijn L et al.(2011). beta-TCP Versus Autologous Bone for Repair of Alveolar Clefts in a Goat Model. CLEFT PALATE-CRANIOFACIAL JOURNAL vol. 48, (6) 654-662.

De Ruiter A, Meijer G, Dormaar T, Janssen N, Van Der Bilt A, Slootweg P, De Bruijn J, Van Rijn L et al.(2011). β-TCP versus autologous bone for repair of alveolar clefts in a goat model. Cleft Palate-Craniofacial Journal vol. 48, (6) 654-662.

Yuan H, Barbieri D, Van Blitterswijk CA, De Bruijn JD(2011). Calcium phosphates and bone induction. vol. 5, 269-280.

Pattappa G, Heywood HK, de Bruijn JD, Lee DA(2011). The metabolism of human mesenchymal stem cells during proliferation and differentiation. J Cell Physiol vol. 226, (10) 2562-2570.

Barbieri D, Yuan H, de Groot F, Walsh WR, de Bruijn JD(2011). Influence of different polymeric gels on the ectopic bone forming ability of an osteoinductive biphasic calcium phosphate ceramic. Acta Biomater vol. 7, (5) 2007-2014.

Yuan HP, Fernandes H, Habibovic P, de Boer J, Barradas AMC, de Ruiter A, Walsh WR, van Blitterswijk CA et al.(2011). 'Smart' biomaterials and osteoinductivity. NAT REV RHEUMATOL vol. 7, (4) 1-1.

Yuan H, Fernandes H, Habibovic P, De Boer J, Barradas AMC, De Ruiter A, Walsh WR, Van Blitterswijk CA et al.(2011). Correspondence: 'Smart' biomaterials and osteoinductivity. Nature Reviews Rheumatology vol. 7, (4)

Wilson CE, van Blitterswijk CA, Verbout AJ, Dhert WJA, de Bruijn JD(2011). Scaffolds with a standardized macro-architecture fabricated from several calcium phosphate ceramics using an indirect rapid prototyping technique. J MATER SCI-MATER M vol. 22, (1) 97-105.

Pattappa G, Heywood HK, de Bruijn JD, Lee DA(2010). The metabolism of human mesenchymal stem cells during proliferation and differentiation. J Cell Physiol

Yuan H, Fernandes H, Habibovic P, De Boer J, Barradas AMC, De Ruiter A, Walsh WR, Van Blitterswijk CA et al.(2010). Osteoinductive ceramics as a synthetic alternative to autologous bone grafting. Proceedings of the National Academy of Sciences of the United States of America vol. 107, (31) 13614-13619.

Xiao Y, Peperzak V, van Rijn L, Borst J, de Bruijn JD(2010). Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells. J Tissue Eng Regen Med vol. 4, (5) 374-386.

Ahmadi R, Burns AJ, de Bruijn JD(2010). Chitosan-based hydrogels do not induce angiogenesis. J Tissue Eng Regen Med vol. 4, (4) 309-315.

van Gaalen SM, Kruyt MC, Geuze RE, de Bruijn JD, Alblas J, Dhert WJA(2010). Use of Fluorochrome Labels in In Vivo Bone Tissue Engineering Research. TISSUE ENG PART B-RE vol. 16, (2) 209-217.

Schop D, van Dijkhuizen-Radersma R, Borgart E, Janssen FW, Rozemuller H, Prins HJ, de Bruijn JD(2010). Expansion of human mesenchymal stromal cells on microcarriers: growth and metabolism. J TISSUE ENG REGEN M vol. 4, (2) 131-140.

van Gaalen SM, Dhert WJA, Kruyt MC, Yuan HP, Oner FC, van Blitterswijk CA, Verbout AJ, de Bruijn JD(2010). Goat Bone Tissue Engineering: Comparing an Intramuscular with a Posterolateral Lumbar Spine Location. TISSUE ENG PT A vol. 16, (2) 685-693.

Barbieri D, Renard AJS, de Bruijn JD, Yuan H(2010). Heterotopic bone formation by nano-apatite containing poly(D,Llactide) composites. European Cells and Materials vol. 19, 252-261.

Janssen FW, van Dijkhuizen-Radersma R, Van Oorschot A, Oostra J, de Bruijn JD, Van Blitterswijk CA(2010). Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study. J TISSUE ENG REGEN M vol. 4, (1) 12-24.

van Gaalen SM, de Bruijn JD, Wilson CE, van Blitterswijk CA, Verbout AJ, Alblas J, Dhert WJA(2010). Relating cell proliferation to in vivo bone formation in porous Ca/P scaffolds. J BIOMED MATER RES A vol. 92A, (1) 303-310.

Brittijn SA, Duivesteijn SJ, Belmamoune M, Bertens LFM, Bitter W, De Bruijn JD, Champagne DL, Cuppen E et al.(2009). Zebrafish development and regeneration: New tools for biomedical research. International Journal of Developmental Biology vol. 53, (5-6) 835-850.

Schop D, Janssen FW, Van Rijn LDS, Fernandes H, Bloem RM, De Bruijn JD, Van Dijkhuizen-Radersma R(2009). Growth, metabolism, and growth inhibitors of mesenchymal stem cells. Tissue Engineering - Part A vol. 15, (8) 1877-1886.

Pattappa G, Jegard NC, Lee DA, de Bruijn JD(2009). The effect of oxygen tension on the proliferation and differentiation of human mesenchymal stem cells. European Cells and Materials vol. 18, (SUPPL. 1)

Pattappa G, Jegard NC, de Bruijn JD, Lee DA(2009). The influence of oxygen tension on the colony formation and proliferation of human mesenchymal stem cells. European Cells and Materials vol. 18, (SUPPL. 2)

Wilkop T, Ramlogan AS, Alberts IL, de Bruijn JD, Ray AK (2009). Surface Plasmon Resonance Imaging for Medical and Biosensing. 2009 IEEE SENSORS, VOLS 1-3. 1493-1496.

Ahmadi R, Burns A, De Bruijn JD(2008). Angiogenesis is stimulated in chitosan-based injectable systems containing human mesenchymal stem cells. 8th World Biomaterials Congress 2008 vol. 3,

Yuan H, De Groot K, Van Blitterswijk CA, De Bruijn JD(2008). Calcium release and/or grain size play a role in cap-induced bone formation. 8th World Biomaterials Congress 2008 vol. 2,

Delawi D, Oner FC, Kruyt MC, Alblas J, Yuan H, Vincken KL, De Bruijn JD, Dhert WJA(2008). Comparing autograft, allograft, and tricalcium phosphate in instrumented posterolateral fusions. 8th World Biomaterials Congress 2008 vol. 1,

Shankar K, De Bruijn JD(2008). Factors secreted by macrophages in response to microstructured calcium phosphates enhance osteogenic differentiation of stem cells. 8th World Biomaterials Congress 2008 vol. 2,

Schop D, Janssen FW, De Bruijn JD, Van Dijkhuizen-Radersma R(2008). Human mesenchymal stem cell proliferation on microcarriers by controlling pH and dissolved oxygen concentration. 8th World Biomaterials Congress 2008 vol. 1,

Yuan H, Hasnath T, De Groot K, Van Blitterswijk CA, De Bruijn JD(2008). Improve bone forming ability of calcium phosphates with zinc chloride (ZnCl2). 8th World Biomaterials Congress 2008 vol. 2,

Barbieri D, Far S, Bao C, Van Blitterswijk C, De Bruijn J, Yuan H(2008). Influence of nano-ha on biological properties of PLA-based composites. 8th World Biomaterials Congress 2008 vol. 2,

Shankar K, De Bruijn JD(2008). Interaction of platelets with osteoinductive materials in comparison to non-osteoinductive materials. 8th World Biomaterials Congress 2008 vol. 2,

Yuan H, De Groot K, Van Blitterswijk CA, De Bruijn JD(2008). Manipulating bone formation in calcium phosphates with microstructures. 8th World Biomaterials Congress 2008 vol. 2,

Ramlogan AS, De Bruijn JD(2008). Mesenchymal stem cell expansion on microspheres: The effect of surface microstructure. 8th World Biomaterials Congress 2008 vol. 3,

Pattappa G, A. Lee D, De Bruijn JD(2008). Metabolic characteristics of human mesenchymal stem cells expanded under normoxic conditions. 8th World Biomaterials Congress 2008 vol. 1,

Ahmadi R, De Bruijn JD(2008). Osteogenesis of MC3T3-E1 cells is enhanced by chitosan-based polymeric systems. 8th World Biomaterials Congress 2008 vol. 4,

Yuan H, De Groot K, Van Blitterswijk CA, De Bruijn JD(2008). Preparation of a resorbable osteoinductive TRi-calcium phosphate ceramic. 8th World Biomaterials Congress 2008 vol. 2,

van Blitterswijk C, Thomsen P, Hubbell J, Cancedda R, de Bruijn JD, Lindahl A, Sohier J, Williams D(2008). Tissue Engineering. Tissue Engineering

Ahmadi R, de Bruijn JD(2008). Biocompatibility and gelation of chitosan-glycerol phosphate hydrogels. J Biomed Mater Res A vol. 86, (3) 824-832.

Xiao YL, Peperzak V, van Rijn L, Borst J, de Bruijn J(2008). Dexamethasone treatment during the expansion phase sustains stemness of mesenchymal stem cells from human bone marrow. CELL RES vol. 18,

Meijer GJ, de Bruijn JD, Koole R, van Blitterswijk CA(2008). Cell based bone tissue engineering in jaw defects. Biomaterials vol. 29, (21) 3053-3061.

Yuan H, de Groot K, van Blitterswijk CA, de Bruijn JD(2008). Preparation of a resorbable osteoinductive tricalcium phosphate ceramic. European Cells and Materials vol. 16, (SUPPL.2)

Kruyt M, De Bruijn J, Rouwkema J, Van Bliterswijk C, Oner C, Verbout A, Dhert W(2008). Analysis of the dynamics of bone formation, effect of cell seeding density, and potential of allogeneic cells in cell-based bone tissue engineering in goats. TISSUE ENG PT A vol. 14, (6) 1081-1088.

Schop D, Janssen FW, Borgart E, de Bruijn JD, van Dijkhuizen-Radersma R(2008). Expansion of mesenchymal stem cells using a microcarrier-based cultivation system: growth and metabolism. J TISSUE ENG REGEN M vol. 2, (2-3) 126-135.

De Bruijn JD, Shankar K, Yuan H, Habibovic P(2008). Osteoinduction and its evaluation. 199-219.

van Blitterswijk C, Thomsen P, Hubbell J, Cancedda R, de Bruijn JD, Lindahl A, Sohier J, Williams D(2008). Tissue Engineering.

de Bruijn JD, Shankar K, Yuan H(2007). Application of osteoconductive materials in bone surgery. European Cells and Materials vol. 14, (SUPPL.1)

Eniwumide JO, Yuan H, Cartmell SH, Meijer GJ, de Bruijn JD(2007). Ectopic bone formation in bone marrow stem cell seeded calcium phosphate scaffolds as compared to autograft and (cell seeded) allograft. Eur Cell Mater vol. 14, 30-38.

Ahmadi R, De Bruijn JD (2007). Chitosan based delivery systems for injectable tissue engineered bone: Human mesenchymal stem cell survival, proliferation and osteogenic differentiation. TISSUE ENGINEERING. vol. 13, 1655-1655.

Eniwumide JO, Yuan H, Cartmell SH, Meijer GJ, de Bruijn JD(2007). Ectopic bone formation in bone marrow stem cell seeded calcium phosphate scaffolds as compared to autograft and (cell seeded) allograft - Discussion with reviewers. EUR CELLS MATER vol. 14, 39-39.

Claase MB, de Bruijn JD, Grijpma DW, Feijen J(2007). Ectopic bone formation in cell-seeded poly(ethylene oxide)/poly(butylene terephthalate) copolymer scaffolds of varying porosity. J Mater Sci Mater Med vol. 18, (7) 1299-1307.

Pattappa G, De Bruijn JD, Lee DA (2007). Mesenchymal stem cells maintain a glycolytic metabolism under normoxic conditions. TISSUE ENGINEERING. vol. 13, 1725-1725.

Ramlogan AS, De Bruijn JD (2007). PHBV, PCL and PLGA microsphere support the attachment and proliferation of goat and human mesenchymal stem cells. TISSUE ENGINEERING. vol. 13, 1741-1741.

Schop D, Janssen FW, Borgart E, De Bruijn JD, Van Dijkhuizen-Radersma R (2007). Successful 3D proliferation of human mesenchymal stem cells on microcarriers. TISSUE ENGINEERING. vol. 13, 1759-1759.

Kruyt MC, Dhert WJA, Oner FC, van Blitterswijk CA, Verbout AJ, de Bruijn JD(2007). Analysis of ectopic and orthotopic bone formation in cell-based tissue-engineered constructs in goats. Biomaterials vol. 28, (10) 1798-1805.

Meijer GJ, De Bruijn JD, Koole R, Van Blitterswijk CA(2007). Cell-based bone tissue engineering. PLoS Medicine vol. 4, (2) 0260-0264.

Meijer GJ, de Bruijn JD, Koole R, van Blitterswijk CA(2007). Cell-based bone tissue engineering. PLoS Med vol. 4, (2)

Both SK, Van der Muijsenberg AJC, Van Blitterswijk CA, De Boer J, De Bruijn JD(2007). A rapid and efficient method for expansion of human mesenchymal stem cells. TISSUE ENG vol. 13, (1) 3-9.

Kruyt MC, Wilson CE, de Bruijn JD, van Blitterswijk CA, Oner CF, Verbout AJ, Dhert WJA(2006). The effect of cell-based bone tissue engineering in a goat transverse process model. BIOMATERIALS vol. 27, (29) 5099-5106.

Yuan H, van Blitterswijk CA, de Groot K, de Bruijn JD(2006). A comparison of bone formation in biphasic calcium phosphate (BCP) and hydroxyapatite (HA) implanted in muscle and bone of dogs at different time periods. J Biomed Mater Res A vol. 78, (1) 139-147.

Yuan H, van Blitterswijk CA, de Groot K, de Bruijn JD(2006). Cross-species comparison of ectopic bone formation in biphasic calcium phosphate (BCP) and hydroxyapatite (HA) scaffolds. Tissue Eng vol. 12, (6) 1607-1615.

Kruyt MC, Persson C, Johansson G, Dhert WJA, de Bruijn JD(2006). Towards injectable cell-based tissue-engineered bone: the effect of different calcium phosphate microparticles and pre-culturing. Tissue Eng vol. 12, (2) 309-317.

Wilson CE, Kruyt MC, de Bruijn JD, van Blitterswijk CA, Oner FC, Verbout AJ, Dhert WJA(2006). A new in vivo screening model for posterior spinal bone formation: comparison of ten calcium phosphate ceramic material treatments. Biomaterials vol. 27, (3) 302-314.

Dekker RJ, de Bruijn JD, Stigter M, Barrere F, Layrolle P, van Blitterswijk CA(2005). Bone tissue engineering on amorphous carbonated apatite and crystalline octacalcium phosphate-coated titanium discs. Biomaterials vol. 26, (25) 5231-5239.

Ahmadi R, Zhou M, de Bruijn JD(2005). The use of thermo-sensitive chitosan as an injectable carrier for bone tissue engineering. European Cells and Materials vol. 10, (SUPPL.2)

van Apeldoorn AA, Aksenov Y, Stigter M, Hofland I, de Bruijn JD, Koerten HK, Otto C, Greve J et al.(2005). Parallel high-resolution confocal Raman SEM analysis of inorganic and organic bone matrix constituents. J R Soc Interface vol. 2, (2) 39-45.

Kruyt MC, De Bruijn JD, Yuan H, Dhert WJA(2004). A simple method for cell-based bone tissue engineering to create osteogenic constructs that show localized bone formation in ceramic scaffolds. Transactions - 7th World Biomaterials Congress

Wilson CE, Kruyt MC, De Bruijn JD, Van Blitterswijk CA, Verbout AJ, Dhert WJA(2004). An in vivo screening model for the parallel assessment of multiple parameters on orthotopic bone formation. Transactions - 7th World Biomaterials Congress

Van Apeldoorn AA, Aksenov Y, Stigter M, Hofland I, De Bruijn JD, Koerten HK, Greve J, Otto C et al.(2004). Confocal Raman scanning electron microscopy a method for parallel non-invasive high resolution analysis of bone samples. Transactions - 7th World Biomaterials Congress

Van Gaalen SM, Dhert WJA, Kruyt MC, Yuan H, Oner FC, Van Blitterswijk CA, Verbout AJ, De Bruijn JD(2004). Goat bone tissue engineering: The effect of implant location. Transactions - 7th World Biomaterials Congress

Yuan H, De Bruijn JD, Zhang X, Van Blitterswijk CA, De Groot K(2004). Influence of sintering temperature on the properties of calcium phosphate ceramics. Transactions - 7th World Biomaterials Congress

Yuan H, Kruyt M, Van Den Doel M, Van Blitterswijk CA, De Groot K, De Bruijn JD(2004). Repair of a critical size bone defect in goat with an osteoinductive calcium phosphate ceramic. Transactions - 7th World Biomaterials Congress

Yuan H, De Bruijn JD, Van Den Doel M, De Groot K, Van Blitterswijk CA(2004). Seeking for a good bone tissue engineering scaffold. Transactions - 7th World Biomaterials Congress

Yuan H, Van Den Doel M, De Groot K, Van Blitterswijk CA, De Bruijn JD(2004). The limitation of implant size in bone tissue engineering. Transactions - 7th World Biomaterials Congress

van Apeldoorn AA, van Manen H-J, Bezemer JM, de Bruijn JD, van Blitterswijk CA, Otto C(2004). Raman imaging of PLGA microsphere degradation inside macrophages. J Am Chem Soc vol. 126, (41) 13226-13227.

de Bruijn JD(2004). A 1-year study of osteoinduction in hydroxyapatite-derived biomaterials in an adult sheep model: Part II. Bioengineering implants to optimize bone replacement in reconstruction of cranial defects - Discussion. PLAST RECONSTR SURG vol. 114, (5) 1164-1165.

Mendes SC, Tibbe JM, Veenhof M, Both S, Oner FC, van Blitterswijk CA, de Bruijn JD(2004). Relation between in vitro and in vivo osteogenic potential of cultured human bone marrow stromal cells. J Mater Sci Mater Med vol. 15, (10) 1123-1128.

Kruyt MC, Stijns MMC, Fedorovich NE, De Bruijn JD, Van Blitterswijk CA, Verbout AJ, Rozemuller H, Hagenbeek A et al.(2004). Genetic marking with the DeltaLNGFR-gene for tracing goat cells in bone tissue engineering. J Orthop Res vol. 22, (4) 697-702.

Kruyt MC, Dhert WJA, Oner C, van Blitterswijk CA, Verbout AJ, de Bruijn JD(2004). Optimization of bone-tissue engineering in goats. J Biomed Mater Res B Appl Biomater vol. 69, (2) 113-120.

Kruyt MC, Dhert WJA, Yuan H, Wilson CE, van Blitterswijk CA, Verbout AJ, de Bruijn JD(2004). Bone tissue engineering in a critical size defect compared to ectopic implantations in the goat. J Orthop Res vol. 22, (3) 544-551.

Kruyt MC, van Gaalen SM, Oner FC, Verbout AJ, de Bruijn JD, Dhert WJA(2004). Bone tissue engineering and spinal fusion: the potential of hybrid constructs by combining osteoprogenitor cells and scaffolds. Biomaterials vol. 25, (9) 1463-1473.

Kruyt MC, Dhert WJA, Oner C, van Blitterswijk CA, Verbout AJ, de Bruijn JD(2004). Osteogenicity of autologous bone transplants in the goat. Transplantation vol. 77, (4) 504-509.

Kruyt MC, de Bruijn JD, Yuan H, van Blitterswijk CA, Verbout AJ, Oner FC, Dhert WJA(2004). Optimization of bone tissue engineering in goats: a peroperative seeding method using cryopreserved cells and localized bone formation in calcium phosphate scaffolds. Transplantation vol. 77, (3) 359-365.

Liu Y, Hunziker EB, Layrolle P, De Bruijn JD, De Groot K(2004). Bone morphogenetic protein 2 incorporated into biomimetic coatings retains its biological activity. Tissue Eng vol. 10, (1-2) 101-108.

van Gaalen SM, Dhert WJA, van den Muysenberg A, Oner FC, van Blitterswijk C, verbout AJ, de Bruijn JD(2004). Bone tissue engineering for spine fusion: an experimental study on ectopic and orthotopic implants in rats. Tissue Eng vol. 10, (1-2) 231-239.

Wilson CE, de Bruijn JD, van Blitterswijk CA, Verbout AJ, Dhert WJA(2004). Design and fabrication of standardized hydroxyapatite scaffolds with a defined macro-architecture by rapid prototyping for bone-tissue-engineering research. J Biomed Mater Res A vol. 68, (1) 123-132.

Deschamps AA, van Apeldoorn AA, Hayen H, de Bruijn JD, Karst U, Grijpma DW, Feijen J(2004). In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate). Biomaterials vol. 25, (2) 247-258.

Fischer EM, Layrolle P, Van Blitterswijk CA, De Bruijn JD(2003). Bone formation by mesenchymal progenitor cells cultured on dense and microporous hydroxyapatite particles. Tissue Eng vol. 9, (6) 1179-1188.

Deschamps AA, van Apeldoorn AA, de Bruijn JD, Grijpma DW, Feijen J(2003). Poly(ether ester amide)s for tissue engineering. Biomaterials vol. 24, (15) 2643-2652.

de Bruijn JD, Fischer EM, Layrolle PJF (2003). Injectable calcium salt bone filler comprising cells. no. PCT/NL2002/000633,

Kruyt MC, de Bruijn JD, Wilson CE, Oner FC, van Blitterswijk CA, Verbout AJ, Dhert WJA(2003). Viable osteogenic cells are obligatory for tissue-engineered ectopic bone formation in goats. Tissue Eng vol. 9, (2) 327-336.

Claase MB, Riekerink MBO, Grijpma DW, Feijen J, Mendes SC, de Bruijn JD (2003). Surface modifications of PEOT/PBT copolymers for the improvement of bone marrow stromal cell attachment. JOURNAL OF CONTROLLED RELEASE. vol. 87, 298-301.

Kruyt MC, De Bruijn J, Veenhof M, Oner FC, Van Blitterswijk CA, Verbout AJ, Dhert WJA(2003). Application and limitations of chloromethyl-benzamidodialkylcarbocyanine for tracing cells used in bone tissue engineering. TISSUE ENG vol. 9, (1) 105-115.

Claase MB, Grijpma DW, Mendes SC, De Bruijn JD, Feijen J(2003). Porous PEOT/PBT scaffolds for bone tissue engineering: preparation, characterization, and in vitro bone marrow cell culturing. J Biomed Mater Res A vol. 64, (2) 291-300.

Claase MB, Olde Riekerink MB, de Bruijn JD, Grijpma DW, Engbers GHM, Feijen J(2003). Enhanced bone marrow stromal cell adhesion and growth on segmented poly(ether ester)s based on poly(ethylene oxide) and poly(butylene terephthalate). Biomacromolecules vol. 4, (1) 57-63.

Mendes SC, Bezemer J, Claase MB, Grijpma DW, Bellia G, Degli-Innocenti F, Reis RL, de Groot K et al.(2003). Evaluation of two biodegradable polymeric systems as substrates for bone tissue engineering. Tissue Eng vol. 9 Suppl 1, S91-101.

Meijer MG, BRUIJN JD, van Blitterswijk CA, Dekker R, Mendes SC(2003). Kweken van een bottransplantaat. Het tandheelkundig jaar, Editors: al, VSE, Bohn Stafleu van Loghum (Houten / Mechelen),

Dekker RJ, van Blitterswijk CA, Hofland I, Engelberts PJ, Li J, de Bruijn JD(2003). Studying the effect of different macrostructures on in vitro cell behaviour and in vivo bone formation using a tissue engineering approach. Novartis Found Symp vol. 249, 148-167.

BRUIJN JD, da Silva Madureira Mendes SC, van Blitterswijk CA (2002). Assay for predeicting cell activity. no. PCT/NL2002/000371,

Yuan H, Van Den Doel M, Li S, Van Blitterswijk CA, De Groot K, De Bruijn JD(2002). A comparison of the osteoinductive potential of two calcium phosphate ceramics implanted intramuscularly in goats. J Mater Sci Mater Med vol. 13, (12) 1271-1275.

Mendes SC, Tibbe JM, Veenhof M, Bakker K, Both S, Platenburg PP, Oner FC, de Bruijn JD et al.(2002). Bone tissue-engineered implants using human bone marrow stromal cells: effect of culture conditions and donor age. Tissue Eng vol. 8, (6) 911-920.

Wilson CE, Dhert WJA, Van Blitterswijk CA, Verbout AJ, De Bruijn JD(2002). Evaluating 3D bone tissue engineered constructs with different seeding densities using the alamarBlue assay and the effect on in vivo bone formation. J Mater Sci Mater Med vol. 13, (12) 1265-1269.

Mendes SC, Sleijster M, Van Den Muysenberg A, De Bruijn JD, Van Blitterswijk CA(2002). A cultured living bone equivalent enhances bone formation when compared to a cell seeding approach. J Mater Sci Mater Med vol. 13, (6) 575-581.

Havenga MJE, Lemckert AAC, Ophorst OJAE, van Meijer M, Germeraad WTV, Grimbergen J, van Den Doel MA, Vogels R et al.(2002). Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease. J Virol vol. 76, (9) 4612-4620.

Deschamps AA, Claase MB, Sleijster WJ, de Bruijn JD, Grijpma DW, Feijen J (2002). Design of segmented poly(ether ester) materials and structures for the tissue engineering of bone. JOURNAL OF CONTROLLED RELEASE. vol. 78, 175-186.

Aksenov Y, Van Apeldoorn AA, De Bruijn JC, Van Blitterswijk CA, Greve J, Otto C(2002). Combined confocal raman microscope with scanning electron microscope; A parallel analysis of inorganic and organic materials. Microscopy and Microanalysis vol. 8, (SUPPL. 2) 1386-1387.

van Apeldoorn AA, Askenov Y, Stigter M, Hofland I, BRUIJN JD, Otto C, Greve J, van Blitterswijk CA (2002). Confocal Raman scanning electron microscopy; a parallel analysis of inorganic and organic constituents synthesized by tissue engineered osteoprogenitor cells. ICEM-15 : proceedings of the 15th International Congress on Electron Microscopy, 1-6 September 2002, Durban, South Africa. Editors: JAA, E, Conference: ICEM 15: The 15th International Congress on Electron Microscopy (Durban, South Africa) from: 01/09/2002 to: 06/09/2002, vol. Vol 2 : Biology and , 357-358.

Mendes SC, De Bruijn JD, Van Blitterswijk CA (2002). Cultured bone on biomaterial substrates - A tissue engineering approach to treat bone defects. POLYMER BASED SYSTEMS ON TISSUE ENGINEERING, REPLACEMENT AND REGENERATION. Editors: Reis, RL, Cohn, D, vol. 86, 265-298.

Mendes SC, Sleijster M, van den Muysenberg A, van Blitterswijk CA, de Bruijn JD (2002). Cultured living bone equivalents enhance bone formation when compared to a cell seeding approach. BIOCERAMICS 14. Editors: Brown, S, Clarke, I, Williams, P, vol. 218-2, 227-231.

Liu Y, Layrolle P, de Bruijn J, van Blitterswijk C, de Groot K(2001). Biomimetic coprecipitation of calcium phosphate and bovine serum albumin on titanium alloy. J Biomed Mater Res vol. 57, (3) 327-335.

Yuan H, Yang Z, De Bruij JD, De Groot K, Zhang X(2001). Material-dependent bone induction by calcium phosphate ceramics: a 2.5-year study in dog. Biomaterials vol. 22, (19) 2617-2623.

Yuan H, De Bruijn JD, Zhang X, Van Blitterswijk CA, De Groot K(2001). Use of an osteoinductive biomaterial as a bone morphogenetic protein carrier. J Mater Sci Mater Med vol. 12, (9) 761-766.

Leeuwenburgh S, Layrolle P, Barrere F, de Bruijn J, Schoonman J, van Blitterswijk CA, de Groot K(2001). Osteoplastic resorption of biomimetic calcium phosphate coatings in vitro. J BIOMED MATER RES vol. 56, (2) 208-215.

BRUIJN JD, Tibbe JM, da Silva Madureira Mendes SC (2001). Cell culture medium containing growth factors and L-glutamine. no. PCT/NL2000/000958,

Mendes SC, Reis RL, Bovell YP, Cunha AM, van Blitterswijk CA, de Bruijn JD(2001). Biocompatibility testing of novel starch-based materials with potential application in orthopaedic surgery: a preliminary study. Biomaterials vol. 22, (14) 2057-2064.

Gomes ME, Reis RL, Cunha AM, Blitterswijk CA, de Bruijn JD(2001). Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions. Biomaterials vol. 22, (13) 1911-1917.

Yuan H, de Bruijn JD, Zhang X, van Blitterswijk CA, de Groot K(2001). Bone induction by porous glass ceramic made from Bioglass (45S5). J Biomed Mater Res vol. 58, (3) 270-276.

Yuan H, De Bruijn JD, Li Y, Feng J, Yang Z, De Groot K, Zhang X(2001). Bone formation induced by calcium phosphate ceramics in soft tissue of dogs: a comparative study between porous alpha-TCP and beta-TCP. J Mater Sci Mater Med vol. 12, (1) 7-13.

Yuan H, Li Y, de Bruijn JD, de Groot K, Zhang X(2000). Tissue responses of calcium phosphate cement: a study in dogs. Biomaterials vol. 21, (12) 1283-1290.

Yuan H, Kurashina K, de Bruijn JD, Li Y, de Groot K, Zhang X(1999). A preliminary study on osteoinduction of two kinds of calcium phosphate ceramics. Biomaterials vol. 20, (19) 1799-1806.

Anderson MLC, Dhert WJA, de Bruijn JD, Dalmeijer RAJ, Leenders H, van Blitterswijk CA, Verbout AJ(1999). Critical size defect in the goat's os ilium - A model to evaluate bone grafts and substitutes. CLIN ORTHOP RELAT R (364) 231-239.

de Bruijn JD, van den Brink I, Mendes S, Dekker R, Bovell YP, van Blitterswijk CA(1999). Bone induction by implants coated with cultured osteogenic bone marrow cells. Adv Dent Res vol. 13, 74-81.

Yuan H, Zou P, Yang Z, Zhang X, De Bruijn JD, De Groot K(1998). Bone morphogenetic protein and ceramic-induced osteogenesis. J Mater Sci Mater Med vol. 9, (12) 717-721.

Dekker RJ, De Bruijn JD, Van Den Brink I, Bovell YP, Layrolle P, Van Blitterswijk CA(1998). Bone tissue engineering on calcium phosphate-coated titanium plates utilizing cultured rat bone marrow cells: a preliminary study. J Mater Sci Mater Med vol. 9, (12) 859-863.

Pypen CMJM, Dessein K, Helsen JA, Gomes M, Leenders H, De Bruijn JD(1998). Comparison of the cytotoxicity of molybdenum as powder and as alloying element in a niobium-molybdenum alloy. J MATER SCI-MATER M vol. 9, (12) 761-765.

Mendes SC, Van Den Brink I, De Bruijn JD, Van Blitterswijk CA(1998). In vivo bone formation by human bone marrow cells: effect of osteogenic culture supplements and cell densities. J Mater Sci Mater Med vol. 9, (12) 855-858.

Yuan H, Yang Z, Li Y, Zhang X, De Bruijn JD, De Groot K(1998). Osteoinduction by calcium phosphate biomaterials. J Mater Sci Mater Med vol. 9, (12) 723-726.

Morais S, Sousa JP, Fernandes MH, Carvalho GS, de Bruijn JD, van Blitterswijk CA(1998). Decreased consumption of Ca and P during in vitro biomineralization and biologically induced deposition of Ni and Cr in presence of stainless steel corrosion products. J BIOMED MATER RES vol. 42, (2) 199-212.

Morais S, Sousa JP, Fernandes MH, Carvalho GS, De Bruijn JD, Van Blitterswijk CA(1998). Effects of AISI 316L corrosion products in in vitro bone formation. Biomaterials vol. 19, (11-12) 999-1007.

De Grauw CJ, De Bruijn JD, Otto C, Greve J, De Grauw K(1996). Investigation of bone and calcium phosphate coatings and crystallinity determination using raman microspectroscopy. Cells and Materials vol. 6, (1-3) 57-62.

de Bruijn JD, vd Brink I, Leenders HL, Bovell YP(1996). Mineralizing human bone marrow cell culture system to evaluate bone replacement materials. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium vol. 1,

de Bruijn JD, Brink IV, Bovell YP(1996). Osteoclast and macrophage responses to artificially produced carbonate-apatite layers and dentin. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium vol. 1,

de Bruijn JD, Bovell YP, Planell JA, Driessens FCM(1996). Osteoclast responses to two types of experimental calcium phosphate bone cements. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium vol. 2,

de Bruijn JD, van Blitterswijk CA, Davies JE(1995). Initial bone matrix formation at the hydroxyapatite interface in vivo. J Biomed Mater Res vol. 29, (1) 89-99.

de Bruijn JD, Bovell YP, van Blitterswijk CA(1994). Structural arrangements at the interface between plasma sprayed calcium phosphates and bone. Biomaterials vol. 15, (7) 543-550.

DEBRUIJN JD, BOVELL YP, VANBLITTERSWIJK CA (1994). Bone-bonding and biodegradation of bioceramic implant materials (Invited). ELECTRON MICROSCOPY 1994, VOLS 3A AND 3B. Editors: Jouffrey, B, Colliex, C, 877-880.

BALDAN N, DEBRUIJN JD, CHERNECKY R, DAVIES JE(1994). CEMENT LINE FORMATION AT THE SURFACES OF BIOACTIVE IMPLANTS. J DENT RES vol. 73, 110-110.

deBruijn JD, Bovell YP, vanBlitterswijk CA (1994). Osteoblast and osteoclast responses to calcium phosphates. BIOCERAMICS, VOL 7. Editors: Andersson, OH, Happonen, RP, YliUrpo, A, 293-298.

de Bruijn JD, Bovell YP, Davies JE, van Blitterswijk CA(1994). Osteoclastic resorption of calcium phosphates is potentiated in postosteogenic culture conditions. J Biomed Mater Res vol. 28, (1) 105-112.

DEBRUIJN JD, FLACH JS, DEGROOT K, VANBLITTERSWIJK CA, DAVIES JE, JONES DB, DOTY SB, DACULSI G et al.(1993). ANALYSIS OF THE BONY INTERFACE WITH VARIOUS TYPES OF HYDROXYAPATITE IN-VITRO. CELL MATER vol. 3, (2) 115-127.

DEBRUIJN JD, KLEIN CPAT, DEGROOT K, VANBLITTERSWIJK CA(1993). INFLUENCE OF CRYSTAL-STRUCTURE ON THE ESTABLISHMENT OF THE BONE-CALCIUM PHOSPHATE INTERFACE IN-VITRO. CELL MATER vol. 3, (4) 407-417.

GOMI K, DEBRUIJN JD, OGURA M, DAVIES JE, JONES S, MULLERMAI C, MILLER SC, OSDOBY P(1993). THE EFFECT OF SUBSTRATUM ROUGHNESS ON OSTEOCLAST-LIKE CELLS IN-VITRO. CELL MATER vol. 3, (2) 151-160.

de Bruijn JD, Klein CP, de Groot K, van Blitterswijk CA(1992). The ultrastructure of the bone-hydroxyapatite interface in vitro. J Biomed Mater Res vol. 26, (10) 1365-1382.

DEBRUIJN JD, VANSLIEDREGT A, DUIVENVOORDEN AM, VANBLITTERSWIJK CA(1992). INVITRO BONE-FORMATION ASSOCIATED WITH APATITE COATED POLYLACTIDE. CELL MATER vol. 2, (4) 329-337.

ORR RD, DEBRUIJN JD, DAVIES JE(1992). SCANNING ELECTRON-MICROSCOPY OF THE BONE INTERFACE WITH TITANIUM, TITANIUM-ALLOY AND HYDROXYAPATITE. CELL MATER vol. 2, (3) 241-251.

Koerten HK, de Bruijn JD, Daems WT(1990). The formation of asbestos bodies by mouse peritoneal macrophages. An in vitro study. Am J Pathol vol. 137, (1) 121-134.