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Publications:  Mr Andrew Clear

Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O et al.(2020). Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells. Cell vol. 181, (6) 1346-1363.e21.
10.1016/j.cell.2020.02.003
Taylor JG, Clear AJ, Truelove E, Calaminici M, Gribben JG (2019). Beyond Exhaustion: The PDL1-PD1 Axis Shapes the Classical Hodgkin Lymphoma Microenvironment. BLOOD. vol. 134,
10.1182/blood-2019-125247
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.(2019). Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma (Leukemia, (2018), 32, 5, (1261-1265), 10.1038/s41375-018-0043-y). Leukemia vol. 33, (6)
10.1038/s41375-019-0425-9
Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X et al.(2019). Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation. Cell Reports vol. 27, (5) 1461-1471.e4.
10.1016/j.celrep.2019.04.014
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57415
Taylor JG, Clear A, Calaminici M, Gribben JG(2019). Programmed cell death protein-1 (PD1) expression in the microenvironment of classical hodgkin lymphoma is similar between favorable and adverse outcome and does not enrich over serial relapses with conventional chemotherapy. Haematologica vol. 104, (1) e42-e44.
10.3324/haematol.2018.204818
Clear AJ, D'Avola A, Agrawal SG, Rassenti LZ, Kipps TJ, Gribben JG, Riches J (2018). B-Cell Receptor Signaling Drives Glycolysis in Chronic Lymphocytic Leukemia Cells. BLOOD. vol. 132,
10.1182/blood-2018-99-112860
Taylor JG, Clear AJ, Matthews J, Calaminici M, Gribben JG (2018). The Treg/Th17 Axis Is Skewed in Classical Hodgkin Lymphoma By PDL1+Ve but Not PDL1-Ve Lymphoma Cells and By Lymphoma MHC Class 2 Expression. BLOOD. vol. 132,
10.1182/blood-2018-99-119126
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.(2018). Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma. Leukemia vol. 32, (5) 1258-1263.
10.1038/s41375-018-0043-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36269
Dürr C, Hanna BS, Schulz A, Lucas F, Zucknick M, Benner A, Clear A, Ohl S et al.(2018). Tumor necrosis factor receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin. Haematologica vol. 103, (4) 688-697.
10.3324/haematol.2017.177808
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward JA et al. (2017). Genomic Profiling Reveals Spatial Intra-Tumor Heterogeneity in Follicular Lymphoma. BLOOD. vol. 130,
Ball JA, Clear AJ, Calaminici M, Stagg A, Lindsay J, Gribben JG, Davies J (2017). Human Gastro-Intestinal Graft-VersusHost Disease Is Mediated By Retinoic Acid-Responsive CD8(+)Effector T-Cells Under IL-23 Polarising Conditions. BLOOD. vol. 130,
Zhang J, Reddy A, Davis N, Moffitt A, Love C, Waldrop A, Leppa S, Pasanen A et al. (2017). Integrative Analysis of 1001 Diffuse Large B Cell Lymphoma Identifies Novel Oncogenic Roles for Rhoa. BLOOD. vol. 130,
Araf S, Korfi K, Nagano A, Cummin TEC, Bentley M, Thorner AR, Ashton-Key M, Calaminici M et al. (2017). Longitudinal Analyses of the Genomic, Transcriptomic, and T Cell Repertoire in Diffuse Large B Cell Lymphoma Demonstrates Changes in Signaling and Immune Recognition at Relapse. BLOOD. vol. 130,
Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A et al.(2017). Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell vol. 171, (2) 481-494.e15.
10.1016/j.cell.2017.09.027
Stevens WBC, Mendeville M, Redd R, Clear AJ, Bladergroen R, Calaminici M, Rosenwald A, Hoster E et al.(2017). Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium. Haematologica vol. 102, (8) 1413-1423.
10.3324/haematol.2017.165415
Zhang J, Reddy A, Love C, Moffitt AB, Rajagopalan D, Leppa S, Pasanen A, Meriranta L et al. (2016). Integrative Genetic and Clinical Analysis through Whole Exome Sequencing in 1001 Diffuse Large B Cell Lymphoma (DLBCL) Patients Reveals Novel Disease Drivers and Risk Groups. BLOOD. vol. 128,
10.1182/blood.V128.22.1087.1087
Smith K, Sheaff M, Elia G, Clear A, Trevisan G, Foxler D, Bridge K, Shepherd S et al. (2016). Loss of LIM-domain proteins LIMD1, Ajuba and WTIP as a novel molecular mechanism for disease aetiology in clear cell renal cell carcinoma (ccRCC). EUROPEAN JOURNAL OF CANCER. vol. 61, S206-S206.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al.(2016). Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma (vol 48, pg 183, 2016). NATURE GENETICS vol. 48, (6) 700-700.
10.1038/ng0616-700b
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Seraihi AFA et al.(2016). Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet vol. 48, (6) 700-700.
10.1038/ng0616-700b
Iyengar S, Ariza-Mcnaughton L, Clear A, Taussig D, Auer R, Roe A, Lillington D, Iqbal S et al.(2016). Characteristics of human primary mantle cell lymphoma engraftment in NSG mice. British Journal of Haematology vol. 173, (1) 165-169.
10.1111/bjh.13581
BALKWILL F, Anne Montfort, Oliver Pearce(2016). Neoadjuvant chemotherapy modulates the immune microenvironment in metastases of tubo-ovarian high-grade serous carcinoma. Clinical Cancer Research
10.1158/1078-0432.CCR-15-2657
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13991
Iacovazzo D, Carlsen E, Lugli F, Chiloiro S, Piacentini S, Bianchi A, Giampietro A, Mormando M et al.(2016). Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: An immunohistochemical study. European Journal of Endocrinology vol. 174, (2) 241-250.
10.1530/EJE-15-0832
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45784
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al.(2016). Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nature Genetics vol. 48, (2) 183-188.
10.1038/ng.3473
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al. (2015). Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nature Genetics.
10.1038/ng.3473
Norster F, Clear AJ, Matthews J, Hoxha E, Gribben J, Jia L (2015). Overexpression of HMGB1 Receptor RAGE Is Associated with Worse Clinical Outcome in Patients with Chronic Lymphocytic Leukemia. BLOOD. vol. 126,
McClanahan F, Hanna B, Miller S, Clear AJ, Lichter P, Gribben JG, Seiffert M(2015). PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia. Blood vol. 126, (2) 203-211.
10.1182/blood-2015-01-622936
Miraki-Moud F, Ghazaly E, Ariza-McNaughton L, Hodby KA, Clear A, Anjos-Afonso F, Liapis K, Grantham M et al.(2015). Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo. Blood vol. 125, (26) 4060-4068.
10.1182/blood-2014-10-608133
Ferguson M, Tysome J, Burns E, Whitehead M, Aksoy E, Clear A, Alusi G, Hiley C et al. (2015). Targeting Innate Host Immunity Through PI3K Delta for Enhancement of Systemic Delivery of Oncolytic Vaccinia Virus. MOLECULAR THERAPY. vol. 23, S258-S259.
10.1016/S1525-0016(16)34258-7
Coutinho R, Clear AJ, Mazzola E, Owen A, Greaves P, Wilson A, Matthews J, Lee A et al.(2015). Revisiting the immune microenvironment of diffuse large B-cell lymphoma using a tissue microarray and immunohistochemistry: Robust semi-automated analysis reveals CD3 and FoxP3 as potential predictors of response to R-CHOP. Haematologica vol. 100, (3) 363-369.
10.3324/haematol.2014.110189
Hanna B, McClanahan F, Clear AJ, Miller S, Lichter P, Seiffert M, Gribben JG(2014). Immune Checkpoint Blockade with Anti-PD-L1 Prevents Immune Dysfuntion and CLL Development in the TCL1 Adoptive Transfer Mouse Model. BLOOD vol. 124, (21)
McCarthy A, Clear AJ, Marzec J, Coutinho R, Petty RD, Matthews J, Wilson A, Iqbal S et al. (2014). Overexpression of BCL-2 Does Not Inhibit Autophagy in Human Follicular and Diffuse Large B-Cell Lymphomas. BLOOD. vol. 124,
Kotsiou E, Okosun J, Clear AJ, Iqbal S, Fitzgibbon J, Gribben JG, Davies JK (2014). TNFRSF14 aberrations in Follicular Lymphoma B Cells Result in Increased Alloresponses in Vitro and in Vivo. BLOOD. vol. 124,
10.1182/blood.v124.21.2426.2426
Duerr C, Hanna B, McClanahan F, Clear AJ, Zenz T, Stilgenbauer S, Gribben JG, Lichter P et al. (2014). The Flavonoid Wogonin Reduces CLL Cell Survival in Vitro and Leukemia Development in E mu-TCL1 Mice By Targeting Aberrant TNF Receptor Signaling. BLOOD. vol. 124,
Tavora B, Reynolds LE, Batista S, Demircioglu F, Fernandez I, Lechertier T, Lees DM, Wong P-P et al.(2014). Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy. Nature vol. 514, (7520) 112-116.
10.1038/nature13541
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6577
JIA L(2014). Dysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2. Oncotarget11653-11668.
10.18632/oncotarget.2605
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12767
Riches JC, O'Donovan CJ, Kingdon SJ, McClanahan F, Clear AJ, Neuberg DS, Werner L, Croce CM et al.(2014). Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations. BLOOD vol. 123, (26) 4101-4110.
10.1182/blood-2014-01-552307
Riches JC, O'Donovan C, Kingdon SJ, McClanahan F, Clear AJ, Neuberg DS, Croce CM, Ramsay AG et al. (2014). Trisomy 12 chronic lymphocytic leukaemia cells exhibit functional upregulation of integrin signalling that is modulated by NOTCH1 mutations. BRITISH JOURNAL OF HAEMATOLOGY. vol. 165, 20-20.
10.1182/blood-2014-01-552307
Jia L, Clear A, Liu F-T, Matthews J, Uddin N, McCarthy A, Hoxha E, Durance C et al.(2014). Extracellular HMGB1 promotes differentiation of nurse-like cells in chronic lymphocytic leukemia. Blood vol. 123, (11) 1709-1719.
10.1182/blood-2013-10-529610
McCarthy A, Marzec J, Clear A, Petty RD, Coutinho R, Matthews J, Wilson A, Iqbal S et al.(2014). Dysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2. Oncotarget vol. 5, (22) 11653-11668.
10.18632/oncotarget.2605
Coutinho R, Clear AJ, Owen A, Wilson A, Matthews J, Lee A, Alvarez R, Gomes da Silva M et al.(2013). Poor concordance among nine immunohistochemistry classifiers of cell-of-origin for diffuse large B-cell lymphoma: implications for therapeutic strategies. Clin Cancer Res vol. 19, (24) 6686-6695.
10.1158/1078-0432.CCR-13-1482
Miraki-Moud F, Ariza-McNaughton L, Ghazaly EA, Hodby KA, Luong P, Clear A, Sohrabi F, Bomalaski J et al. (2013). Arginine Deprivation With Pegylated Arginine Deiminase Induces Death Of Acute Myeloid Leukaemia Cells In Vivo. BLOOD. vol. 122,
10.1182/blood.V122.21.1458.1458
Ene-Obong A, Clear AJ, Watt J, Wang J, Fatah R, Riches JC, Marshall JF, Chin-Aleong J et al.(2013). Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma. Gastroenterology vol. 145, (5) 1121-1132.
10.1053/j.gastro.2013.07.025
Bödör C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S et al.(2013). EZH2 mutations are frequent and represent an early event in follicular lymphoma. Blood vol. 122, (18) 3165-3168.
10.1182/blood-2013-04-496893
Greaves P, Clear A, Owen A, Iqbal S, Lee A, Matthews J, Wilson A, Calaminici M et al.(2013). Defining characteristics of classical Hodgkin lymphoma microenvironment T-helper cells. Blood vol. 122, (16) 2856-2863.
10.1182/blood-2013-06-508044
Kiaii S, Clear AJ, Ramsay AG, Davies D, Sangaralingam A, Lee A, Calaminici M, Neuberg DS et al.(2013). Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation. J Clin Oncol vol. 31, (21) 2654-2661.
10.1200/JCO.2012.44.2137
Liapis K, Clear A, Owen A, Coutinho R, Greaves P, Lee AM, Montoto S, Calaminici M et al.(2013). The microenvironment of AIDS-related diffuse large B-cell lymphoma provides insight into the pathophysiology and indicates possible therapeutic strategies. Blood vol. 122, (3) 424-433.
10.1182/blood-2013-03-488171
Marafioti T, Copie-Bergman C, Calaminici M, Paterson JC, Shende VH, Liu H, Baia M, Ramsay AD et al.(2013). Another look at follicular lymphoma: immunophenotypic and molecular analyses identify distinct follicular lymphoma subgroups. HISTOPATHOLOGY vol. 62, (6) 860-875.
10.1111/his.12076
Okosun J, Clear A, Iqbal S, Matthews J, Gribben J, Fitzgibbon J, Davies J (2013). TNFRSF14 aberrations are associated with death from acute GvHD after reduced-intensity conditioned allogeneic haematopoietic stem cell transplantation for follicular lymphoma. BONE MARROW TRANSPLANTATION. vol. 48, S169-S169.
Iyengar S, Clear A, Bödör C, Maharaj L, Lee A, Calaminici M, Matthews J, Iqbal S et al.(2013). P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse. Blood vol. 121, (12) 2274-2284.
10.1182/blood-2012-10-460832
Greaves P, Clear A, Coutinho R, Wilson A, Matthews J, Owen A, Shanyinde M, Lister TA et al.(2013). Expression of FOXP3, CD68, and CD20 at diagnosis in the microenvironment of classical Hodgkin lymphoma is predictive of outcome. J Clin Oncol vol. 31, (2) 256-262.
10.1200/JCO.2011.39.9881
Butler T, Montoya A, Clear AJ, Coutinho R, Taussig DC, Cutillas P, Gribben JG (2012). Anergic Response to B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia: The Differing Roles of IgD and IgM in the Microenvironment and Peripheral Blood. BLOOD. vol. 120,
10.1182/blood.V120.21.2889.2889
Iyengar S, Ariza-McNaughton L, Clear AJ, Roe A, Lillington D, Taussig DC, Gribben JG, Joel S et al. (2012). Human Primary Mantle Cell Lymphoma Can Be Established in NOD/SCID/IL2R gamma-Null Mice. BLOOD. vol. 120,
10.1182/blood.V120.21.1565.1565
Kiaii S, Clear AJ, Gribben JG (2012). Impact of Tumor Infiltrating T Cells in Patients with Diffuse Large B-Cell Lymphoma. BLOOD. vol. 120,
10.1182/blood.V120.21.1572.1572
Iyengar S, Clear AJ, Boedor C, Maharaj L, Matthews J, Auer R, Iqbal S, Gribben JG et al. (2012). Increased Tonic PI3K Signaling Through p110 alpha Can Limit the Efficacy of P110 delta -Selective Inhibition in Mantle Cell Lymphoma, Particularly with Multiple Relapse. BLOOD. vol. 120,
10.1182/blood.V120.21.1652.1652
Ramsay AG, Clear AJ, Fatah R, Gribben JG(2012). Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood vol. 120, (7) 1412-1421.
10.1182/blood-2012-02-411678
Ramsay G, Clear A, Fatah R, Gribben J (2012). MULTIPLE INHIBITORY LIGANDS INDUCE T CELL IMMUNOLOGICAL SYNAPSE DYSFUNCTION IN HEMATOLOGIC MALIGNANCY THAT CAN BE BLOCKED WITH LENALIDOMIDE - DEFINING A REVERSIBLE IMMUNE EVASION MECHANISM IN CANCER. HAEMATOLOGICA. vol. 97, 230-230.
Greaves P, Clear A, Owen A, Wilson A, Matthews J, Calaminici M, Gribben J (2012). THE MICROENVIRONMENT IN CLASSICAL HODGKIN LYMPHOMA SHOWS EVIDENCE OF A TH1 AND NOT TH2 RESPONSE WITH TBET EXPRESSION BEING ASSOCIATED WITH IMPROVED SURVIVAL AND EBV STATUS. HAEMATOLOGICA. vol. 97, 455-455.
Ramsay AG, Clear AJ, Davenport A, Fatah R, Gribben JG (2011). Chronic Lymphocytic Leukemia Cells Co-Opt CD200,.CD270, CD274 and CD276 to Induce Impaired Actin Polarization At the T Cell Immune Synapse. BLOOD. vol. 118, 364-365.
Coutinho R, Clear AJ, Owen DA, Greaves P, Hallam SL, Wilson A, Matthews J, Calaminici M et al. (2011). Exploring the Immune Microenvironment of Diffuse Large B Cell Lymphoma in a Tissue Microarray: Predicting Survival with a Score That Incorporates Macrophages, Cytotoxic and Regulatory T Cells. BLOOD. vol. 118, 434-435.
Kiaii S, Clear AJ, Sangaralingam A, Gribben JG (2011). Impact of Tumor Infiltrating T Cells in Patients with Follicular Lymphoma At Diagnosis. BLOOD. vol. 118, 349-349.
Iyengar S, Clear AJ, Owen A, Maharaj L, Matthews J, Calaminici M, Auer R, Ghazaly E et al. (2011). PI3K Inhibition with GDC-0941 Has Greater Efficacy Compared to p110 delta-Selective Inhibition with CAL-101 in Mantle Cell Lymphoma and May Be Particularly Advantageous in Multiply Relapsed Patients. BLOOD. vol. 118, 719-719.
Greaves P, Clear AJ, Owen A, Wilson A, Matthews J, Calaminici M, Gribben JG (2011). The PD1/PD-L1 Axis in the Classical Hodgkin Lymphoma Microenvironment: PD-1 Is Rarely Expressed but Identifies Patients with High-Risk Disease. BLOOD. vol. 118, 678-678.
Kiaii S, Clear AJ, Davis D, Ramsay AG, Sangaralingam A, Gribben JG (2011). DEFECTS AND ABNORMALITIES IN INFILTRATING T CELLS IN PATIENTS WITH FOLLICULAR LYMPHOMA AT DIAGNOSIS. ANNALS OF ONCOLOGY. vol. 22, 84-84.
Greaves P, Clear A, Owen A, Matthews J, Macdougall F, Wilson A, Lister A, Calaminici M et al. (2011). TOTAL NUMBER OF B CELLS, BUT NOT T CELLS AT DIAGNOSIS IN THE CLASSICAL HODGKIN LYMPHOMA MICROENVIRONMENT IS PREDICTIVE OF SURVIVAL. ANNALS OF ONCOLOGY. vol. 22, 153-153.
Szlosarek PW, Luong F, Clear A, Taussig D, Joel S, Calaminici M, Debernardi S, Fitzgibbon J et al.(2011). Pegylated arginine deiminase (ADI-PEG20) as a potential novel therapy for argininosuccinate synthetase-deficient acute myeloid leukemia. CANCER RESEARCH vol. 71,
Bödör C, O'Riain C, Wrench D, Matthews J, Iyengar S, Tayyib H, Calaminici M, Clear A et al.(2011). EZH2 Y641 mutations in follicular lymphoma. Leukemia vol. 25, (4) 726-729.
10.1038/leu.2010.311
Greaves P, Clear AJ, Owen DA, Macdougall F, Wilson A, Lister A, Calaminici M, Gribben JG (2010). An Immunohistochemical Score Based On CD68 and FOXP3 Expression In the Tumour Microenvironment at Diagnosis Defines Prognostic Groups In Both Early and Advanced Stage Classical Hodgkin Lymphoma. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 330-330.
Kiaii S, Clear AJ, Ramsay AG, Sangaralingam A, Gribben JG (2010). Differential Gene Expression Profile Identifies Defects and Abnormalities In Infiltrating T Cells In Patients With Follicular Lymphoma at Diagnosis. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 66-67.
Kiaii S, Clear AJ, Ramsay AG, Sangaralingam A, Gribben JG (2010). Differential Gene Expression Profile Identifies Defects and Abnormalities In Infiltrating T Cells In Patients with Follicular Lymphoma at Diagnosis. BLOOD. vol. 116, 66-67.
Ramsay AG, Clear AJ, Davenport A, Fatah R, Gribben JG (2010). Functional Screening Studies Identify Combinational Activity of PD L1 and CD200 In Mediating Dysfunctional T Cell Immunological Synapse Formation In Chronic Lymphocytic Leukemia. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 306-307.
Ramsay AG, Clear AJ, Davenport A, Fatah R, Gribben JG (2010). Functional Screening Studies Identify Combinational Activity of PD-L1 and CD200 In Mediating Dysfunctional T Cell Immunological Synapse Formation In Chronic Lymphocytic Leukemia. BLOOD. vol. 116, 306-307.
Wrench D, Sangaralingam A, Tayyib H, Kang MK, Riain C, Gupta M, Carlotti E, Bodor C et al. (2010). TNERSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenviroment In Transformed Follicular Lymphoma. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 349-349.
Wrench D, Sangaralingam A, Tayyib H, Kang MK, Riain C, Gupta M, Carlotti E, Bodor C et al. (2010). TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma. BLOOD. vol. 116, 349-349.
Clear AJ, Lee AM, Calaminici M, Ramsay AG, Morris KJ, Hallam S, Kelly G, Macdougall F et al.(2010). Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment. Blood vol. 115, (24) 5053-5056.
10.1182/blood-2009-11-253260
O'Riain C, Smith P, Clear A, Wrench D, Gupta M, Bodor C, Matolcsy A, Calaminici M et al. (2010). EZH2 MUTATION IN FOLLICULAR LYMPHOMA. HAEMATOLOGICA. vol. 95, 167-167.
O' Riain C, Smith P, Clear A, Wrench D, Gupta M, Bodor C, Matolcsy A, Calaminici M et al. (2010). EZH2 MUTATION IN FOLLICULAR LYMPHOMA. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 167-167.
Masir N, Jones M, Lee AM, Goff LK, Clear AJ, Lister A, Marafioti T, Mason DY(2010). The expression of Bcl-2 by proliferating cells varies in different categories of B-cell lymphoma. HISTOPATHOLOGY vol. 56, (5) 617-626.
10.1111/j.1365-2559.2010.03524.x
O'Riain C, Calaminici M, Clear A, Braziel RM, Gascoyne RD, Rosenwald A, Campo E, Smeland EB et al. (2010). DNA Methylation and Polycomb Repression in Follicular Lymphoma. MODERN PATHOLOGY. vol. 23, 315A-315A.
Ramsay AG, Clear AJ, Kelly G, Fatah R, Matthews J, Macdougall F, Lister TA, Lee AM et al.(2009). Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy. Blood vol. 114, (21) 4713-4720.
10.1182/blood-2009-04-217687
Masir N, Campbell LJ, Goff LK, Jones M, Marafioti T, Cordell J, Clear AJ, Lister TA et al.(2009). BCL2 protein expression in follicular lymphomas with t(14;18) chromosomal translocations. BRIT J HAEMATOL vol. 144, (5) 716-725.
10.1111/j.1365-2141.2008.07528.x
Ramsay AG, Clear AJ, Fatah R, Gribben JG (2008). Co-Treatment with Panobinostat Enhances Bortezomib-Induced Unfolded Protein Response, Endoplasmic Reticulum Stress and Apoptosis of Human Mantle Cell Lymphoma Cells. BLOOD. vol. 112, 327-327.
Ramsay AG, Xing D-X, Decker WK, Burks JK, Wierda WG, Gribben JG, Shpall EJ (2008). Compared to Adult Peripheral Blood T Cells, Cord Blood T Cells Show Enhanced Immunological Recognition of Chronic Lymphocytic Leukemia Tumor Cells. BLOOD. vol. 112, 813-813.
10.1182/blood.V112.11.885.885
Clear AJ, Lee AM, Morris KJ, Calaminici M, Macdougall F, Goff LK, Lister TA, Gribben JG (2008). Extended Focal Imaging Reveals An Improved Gauge of Angiogenic Activity and Highlights the Role of Angiogenesis in Survival and Time to Transformation in Follicular Lymphoma. BLOOD. vol. 112, 975-975.
Ramsay AG, Clear AJ, Fatah R, Gribben JG (2008). Lenalidomide Repairs Suppressed T Cell Immunological Synapse Formation in Follicular Lymphoma. Conference: 50th Annual Meeting of the American- Society-of-Hematology (San Francisco, CA) from: 06/12/2008 to: 09/12/2008,
Proto-Siqueira R, Panepucci RA, Careta FP, Lee A, Clear A, Morris K, Owen C, Rizzatti EG et al.(2008). SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL. BLOOD vol. 112, (2) 394-397.
10.1182/blood-2007-11-124065
Lee AM, Clear AJ, Morris KJ, Calaminici MR, Matthews J, Gribben JG, Lister TA (2008). Examination of changes in tumour microenvironment of follicular lymphoma using serial sample tissue microarrays. ANNALS OF ONCOLOGY. vol. 19, 179-179.
Lee AM, Clear AJ, Morris KJ, Calaminici MR, Matthews J, Gribben JG, Lister TA (2008). The impact of tumour microenvironment in diagnostic follicular lymphoma samples using tissue microarrays. ANNALS OF ONCOLOGY. vol. 19, 126-126.
Clear AJ, Lee AM, Morris KJ, Calaminici M, Macdougall F, Proto-Siqueira R, Goff LK, Lister TA et al. (2007). Angiogenesis assessed in tissue microarrays of diagnostic follicular lymphoma correlates with outcome. BLOOD. vol. 110, 768A-768A.
Proto-Siqueira R, Panepucci RA, Careta FP, Rizzatti EG, Lee A, Clear A, Morris K, Falcao RP et al. (2007). SAGE analysis demonstrates increased expression of TOSO contributing to Fas mediated resistance in CLL. BLOOD. vol. 110, 340A-340A.
10.1182/blood.V110.11.1121.1121
Lee AM, Clear A, Calaminici M, Macdougall F, Goff L, Gribben JG (2006). Increased CD69 and decreased CD4 expressing cells in tissue microarray (TMA) in diagnostic lymph node biopsies are associated with poor outcome in CLL/SLL. BLOOD. vol. 108, 787A-787A.
10.1182/blood.V108.11.2781.2781
Lee AM, Clear AJ, Calaminici M, Davies AJ, Jordan S, MacDougall F, Matthews J, Norton AJ et al. (2006). Number of CD4(+) cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome. JOURNAL OF CLINICAL ONCOLOGY. vol. 24, 5052-5059.
10.1200/JCO.2006.06.4642
Davies AJ, Lee AM, Taylor C, Clear AJ, Goff LK, Iqbal S, Cuthbert-Heavens D, Calaminici M et al.(2005). A limited role for TP53 mutation in the transformation of follicular lymphoma to diffuse large B-cell lymphoma. LEUKEMIA vol. 19, (8) 1459-1465.
10.1038/sj.leu.2403802
Berney DM, Argyle K, Clear A, Oliver RTD (2005). Tissue micro array of a historical archive: The British Testicular Tumour Panel series. JOURNAL OF PATHOLOGY. vol. 205, 15-15.
Lee A, Davies AJ, Clear A, Calaminici M, Matthews J, Norton A, Wright G, Staudt MLM et al. (2005). Tissue microarray is a useful tool in the evaluation of genes implicated in transformation of follicular lymphoma. JOURNAL OF PATHOLOGY. vol. 205, 11-11.
Berney DM, Argyle K, Clear A, Oliver RTD (2005). Tissue Microarray of the British testicular tumour panel series: Mining a historical archive. LABORATORY INVESTIGATION. vol. 85, 129A-129A.
Berney DM, Argyle K, Clear A, Oliver RTD (2005). Tissue microarray of the British testicular tumour panel series: Mining a historical archive. MODERN PATHOLOGY. vol. 18, 129A-129A.
Davies AJ, Lee AM, Taylor C, Clear AJ, Goff LK, Iqbal S, Cuthbert-Heavens D, Calaminici M et al. (2004). Sequential time-point mutational analysis of TP53 in follicular lymphoma undergoing transformation to large B-cell lymphoma. BLOOD. vol. 104, 382A-382A.
Lee A, Davies A, Clear A, Calaminici M, Matthews J, Norton A, Wright G, Staudt LM et al. (2004). Tissue microarray is a useful tool in the evaluation of genes implicated in transformation of follicular lymphoma. BLOOD. vol. 104, 624A-624A.
10.1182/blood.v104.11.2267.2267
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