Publications: Dr Dianne Cooper

Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L et al. ( 2024 ) . Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues . EMBO Reports vol. 25 , ( 9 ) 3842 - 3869 .

Hussain MT, Austin-Williams S, Wright TD, Dhawan UK, Pinto AL, Cooper D, Norling LV ( 2024 ) . β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis . International Journal of Molecular Sciences vol. 25 , ( 9 )

Fu H, Vuononvirta J, Fanti S, Bonacina F, D’Amati A, Wang G, Poobalasingam T, Fankhaenel M et al. ( 2023 ) . The Glucose Transporter 2 regulates CD8+ T cell function via environment sensing . Nature Metabolism

Sabatucci A, Girella A, Di Bartolomeo M, Pucci M, Vismara M, Benatti B, Blacksell IA, Cooper D et al. ( 2023 ) . A possible role for G-quadruplexes formation and DNA methylation at IMOOD gene promoter in Obsessive Compulsive Disorder . Advances in Biological Regulation vol. 89 ,

Norling LV, Cooper D ( 2023 ) . Being old and female is an inflammatory combination . Journal of Leukocyte Biology vol. 114 , ( 4 ) 299 - 300 .

D'Acquisto F, D'Addario C, Cooper D, Pallanti S, Blacksell I ( 2023 ) . Peripheral control of psychiatric disorders: Focus on OCD. Are we there yet? . Comprehensive Psychiatry vol. 123 ,

Poston RN, Chughtai J, Ujkaj D, Louis H, Leake DS, Cooper D ( 2022 ) . Monocytic Cell Adhesion to Oxidised Ligands: Relevance to Cardiovascular Disease . Biomedicines vol. 10 , ( 12 )

Krautter F, Hussain MT, Zhi Z, Lezama DR, Manning JE, Brown E, Marigliano N, Raucci F et al. ( 2022 ) . Galectin-9: A novel promoter of atherosclerosis progression . Atherosclerosis vol. 363 , 57 - 68 .

Law HL, Cooper D ( 2022 ) . Methods for Assessing the Effects of Galectins on Leukocyte Trafficking and Clearance . Galectins , vol. 2442 , Springer Nature

Hamilton A, Rizzo R, Brod S, Ono M, Perretti M, Cooper D, D'Acquisto F ( 2022 ) . The immunomodulatory effects of social isolation in mice are linked to temperature control . Brain Behavior and Immunity vol. 102 , 179 - 194 .

Iqbal AJ, Krautter F, Blacksell IA, Wright RD, Austin‐Williams SN, Voisin M, Hussain MT, Law HL et al. ( 2021 ) . Galectin‐9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin‐dependent manner . The FASEB Journal vol. 36 , ( 1 )

Chen J, Norling LV, Mesa JG, Silva MDP, Burton SE, Reutelingsperger C, Perretti M, Cooper D ( 2021 ) . Annexin A1 attenuates cardiac diastolic dysfunction in mice with inflammatory arthritis . Proceedings of the National Academy of Sciences of the United States of America vol. 118 , ( 38 )

Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS et al. ( 2021 ) . Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation . Immunity vol. 54 , ( 9 ) 1989 - 2004.e9 .

Oggero S, de Gaetano M, Marcone S, Fitzsimons S, Pinto AL, Ikramova D, Barry M, Burke D et al. ( 2021 ) . Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity . Journal of Extracellular Vesicles vol. 10 , ( 6 )

Chen J, Norling LV, Cooper D ( 2021 ) . Cardiac Dysfunction in Rheumatoid Arthritis: The Role of Inflammation . Cells vol. 10 , ( 4 )

Gilbert SG, Krautter F, Cooper D, Chimen M, Iqbal AJ, Spill F ( 2020 ) . CASTLE: cell adhesion with supervised training and learning environment . Journal of Physics D: Applied Physics vol. 53 , ( 42 ) 424002 - 424002 .

Norling L, Cooper D, Law H, Wright R, Iqbal A ( 2020 ) . A pro-resolving role for Galectin-1 in acute inflammation . Frontiers in Pharmacology vol. 11 , ( 274 )

Goldberg R, Scotta C, Cooper D, Nissim-Eliraz E, Nir E, Tasker S, Irving PM, Sanderson J et al. ( 2019 ) . Correction of Defective T-Regulatory Cells From Patients With Crohn’s Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α . Gastroenterology vol. 156 , ( 6 ) 1775 - 1787 .

Oggero S, Van Gorp R, Cooper D, Norling L, Schurgers L, Reutelinsperger C, Perretti M ( 2019 ) . Monocyte and not Neutrophil derived microvesicles are able to activate endothelial cells and smooth muscle cells and to enhance recruitment of PMN in a Flow Chamber based assay . EUROPEAN JOURNAL OF CLINICAL INVESTIGATION . vol. 49 , 198 - 199 .

Goldberg R, Scotta C, Cooper D, Irving P, Sanderson J, Shpigel N, Marelli-Berg F, Lombardi G et al. ( 2017 ) . OC-066 Gut specific regulatory t cells – a new frontier for crohn’s disease therapy . Gut . vol. 66 ,

Gittens BR, Bodkin JV, Nourshargh S, Perretti M, Cooper D ( 2017 ) . Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation . The Journal of Immunology vol. 198 , ( 11 ) 4458 - 4469 .

Piovezan AP, Batisti AP, Benevides MLACS, Turnes BL, Martins DF, Kanis L, Duarte ECW, Cavalheiro AJ et al. ( 2017 ) . Hydroalcoholic crude extract of Casearia sylvestris Sw. reduces chronic post-ischemic pain by activation of pro-resolving pathways . Journal of Ethnopharmacology vol. 204 , 179 - 188 .

Goldberg R, Scotta C, Cooper D, Eliraz E, Nir E, Irving P, Sanderson J, Shpigel N et al. ( 2017 ) . OP028 Gut specific regulatory T cells – a new frontier for Crohn's disease therapy . Journal of Crohn's and Colitis vol. 11 , ( suppl_1 ) s17 - s17 .

Perretti M, Cooper D, Dalli J, Norling LV ( 2017 ) . Immune resolution mechanisms in inflammatory arthritis . Nat Rev Rheumatol vol. 13 , ( 2 ) 87 - 99 .

Goldberg R, Scotta C, Cooper D, Eliraz E, Nir E, Irving P, Sanderson J, Shpigel N et al. ( 2017 ) . Gut specific regulatory T cells - a new frontier for Crohn's disease therapy . JOURNAL OF CROHNS & COLITIS . vol. 11 , S17 - S17 .

Boardman DA, Philippeos C, Fruhwirth GO, Ibrahim MA, Hannen RF, Cooper D, Marelli-Berg FM, Watt FM et al. ( 2016 ) . Expression of a chimeric antigen receptor specific for donor HLA class I enhances the potency of human regulatory T cells in preventing human skin transplant rejection . Am J Transplant

Wright RD, Souza PR, Flak MB, Thedchanamoorthy P, Norling LV, Cooper D ( 2016 ) . Galectin-3-null mice display defective neutrophil clearance during acute inflammation . J Leukoc Biol

Iqbal AJ, Barrett TJ, Taylor L, McNeill E, Manmadhan A, Recio C, Carmineri A, Brodermann MH et al. ( 2016 ) . Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo . ELIFE vol. 5 , Article ARTN e15190 ,

Barrett TJ, Iqbal AJ, Taylor L, McNeill E, Manmadhan A, White GE, Cooper D, DiDonato JA et al. ( 2016 ) . Abstract 575: Acute Exposure to Apolipoprotein AI Inhibits Macrophage and Macrophage Chemotaxis i n vitro and Recruitment i n vivo . Arteriosclerosis Thrombosis and Vascular Biology vol. 36 , ( suppl_1 )

Holloway PM, Durrenberger PF, Trutschl M, Cvek U, Cooper D, Orr AW, Perretti M, Getting SJ et al. ( 2015 ) . Both MC1 and MC3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion–Induced Neutrophil Recruitment . Arteriosclerosis Thrombosis and Vascular Biology vol. 35 , ( 9 ) 1936 - 1944 .

Komarowska I, Coe D, Wang G, Haas R, Mauro C, Kishore M, Cooper D, Nadkarni S et al. ( 2015 ) . Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release . Immunity vol. 42 , ( 6 ) 1087 - 1099 .

Wright RD, Cooper D ( 2014 ) . Glycobiology of leukocyte trafficking in inflammation . Glycobiology vol. 24 , ( 12 ) 1242 - 1251 .

Gittens BR, Wright RD, Cooper D ( 2014 ) . Methods for Assessing the Effects of Galectins on Leukocyte Trafficking . Methods in Molecular Biology vol. 1207 , 133 - 151 .

Ahmed TJ, Kaneva MK, Pitzalis C, Cooper D, Perretti M ( 2014 ) . Resolution of inflammation: examples of peptidergic players and pathways . Drug Discov Today vol. 19 , ( 8 ) 1166 - 1171 .

Ayoub SS, Norling LV, Leoni G, Cooper D, Perretti M ( 2014 ) . Cell Adhesion Molecules . Fundamentals of Inflammation , Cambridge University Press (CUP)

Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ et al. ( 2014 ) . Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation . Nat Commun vol. 5 ,

Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ et al. ( 2014 ) . Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation . IMMUNOLOGY vol. 143 , 124 - 124 .

Curciarello R, Steele A, Cooper D, MacDonald TT, Kruidenier L, Kudo T ( 2014 ) . The role of Galectin-1 and Galectin-3 in the mucosal immune response to Citrobacter rodentium infection . PLoS One vol. 9 , ( 9 )

Iqbal AJ, Cooper D, Vugler A, Gittens BR, Moore A, Perretti M ( 2013 ) . Endogenous galectin-1 exerts tonic inhibition on experimental arthritis . J Immunol vol. 191 , ( 1 ) 171 - 177 .

Rhodes DH, Pini M, Castellanos KJ, Montero-Melendez T, Cooper D, Perretti M, Fantuzzi G ( 2013 ) . Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function . Obesity (Silver Spring) vol. 21 , ( 2 ) 310 - 319 .

Pang J, Rhodes DH, Pini M, Akasheh RT, Castellanos KJ, Cabay RJ, Cooper D, Perretti M et al. ( 2013 ) . Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice . PLoS One vol. 8 , ( 2 )

Gittens B, Perretti M, Cooper D ( 2013 ) . Investigating Novel Roles for Exogenous and Endogenous Galectin-3 in Controlling Vascular Inflammation . FASEB JOURNAL . vol. 27 ,

Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D et al. ( 2012 ) . The peritoneal tumour microenvironment of high-grade serous ovarian cancer . J Pathol vol. 227 , ( 2 ) 136 - 145 .

Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M ( 2012 ) . A role for Galectin‐9 in neutrophil trafficking . The FASEB Journal . vol. 26 , 136.7 - 136.7 .

Cooper D, Iqbal AJ, Gittens BR, Cervone C, Perretti M ( 2012 ) . The effect of galectins on leukocyte trafficking in inflammation: sweet or sour? . Ann N Y Acad Sci vol. 1253 , 181 - 192 .

Cooper D ( 2012 ) . A Therapeutic Role for Galectins in Acute Inflammation? . GALECTINS AND DISEASE IMPLICATIONS FOR TARGETED THERAPEUTICS . vol. 1115 , 325 - 342 .

Nadkarni S, Cooper D, Brancaleone V, Bena S, Perretti M ( 2011 ) . Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes . Arterioscler Thromb Vasc Biol vol. 31 , ( 11 ) 2749 - 2759 .

Iqbal AJ, Cooper D, Vugler AD, Moore A, Perretti M ( 2011 ) . ENDOGENOUS GALECTIN-1 INHIBITS EXPERIMENTAL ARTHRITIS: A POTENTIAL SWEET THERAPEUTIC TARGET? . INFLAMMATION RESEARCH . vol. 60 , 186 - 187 .

Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M ( 2011 ) . GALECTIN-9: SWEETENING LEUKOCYTE RECRUITMENT . INFLAMMATION RESEARCH . vol. 60 , 87 - 88 .

Roviezzo F, Brancaleone V, De Gruttola L, Vellecco V, Bucci M, D'Agostino B, Cooper D, Sorrentino R et al. ( 2011 ) . Sphingosine-1-phosphate modulates vascular permeability and cell recruitment in acute inflammation in vivo . J Pharmacol Exp Ther vol. 337 , ( 3 ) 830 - 837 .

Iqbal AJ, Sampaio ALF, Maione F, Greco KV, Niki T, Hirashima M, Perretti M, Cooper D ( 2011 ) . Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect . Am J Pathol vol. 178 , ( 3 ) 1201 - 1209 .

Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M ( 2010 ) . Human RCAN3 gene expression and cell growth in endothelial cells . INT J MOL MED vol. 26 , ( 6 ) 913 - 918 .

Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F ( 2010 ) . Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature . Blood vol. 116 , ( 20 ) 4288 - 4296 .

Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M ( 2010 ) . Human RCAN3 gene expression and cell growth in endothelial cells . International Journal of Molecular Medicine vol. 26 , ( 6 ) 913 - 918 .

Yazid S, Leoni G, Getting SJ, Cooper D, Solito E, Perretti M, Flower RJ ( 2010 ) . Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization . Arterioscler Thromb Vasc Biol vol. 30 , ( 9 ) 1718 - 1724 .

Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M ( 2010 ) . A role for Galectin-9 in neutrophil trafficking . FASEB JOURNAL vol. 24 ,

Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M ( 2010 ) . Human RCAN3 gene expression and cell growth in endothelial cells . International Journal of Molecular Medicine vol. 26 , ( 6 ) 913 - 918 .

Cooper D, Ilarregui JM, Pesoa SA, Croci DO, Perretti M, Rabinovich GA ( 2010 ) . Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate . vol. 480 ,

Hunter C, Kadakia TB, Cooper D, Perretti M, Schwartz RC, Brown SB ( 2010 ) . Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands . THESCIENTIFICWORLDJOURNAL vol. 10 , 1580 - 1596 .

Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M et al. ( 2009 ) . Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis . NATURE vol. 461 , ( 7268 ) 1287 - U125 .

Norling LV, Perretti M, Cooper D ( 2009 ) . Endogenous galectins and the control of the host inflammatory response . J Endocrinol vol. 201 , ( 2 ) 169 - 184 .

Perretti M, Iqbal A, Cooper D ( 2009 ) . Galectin 1 Controls Cell Trafficking in Inflammation . GLYCOBIOLOGY . vol. 19 , 1310 - 1310 .

Dalli J, Norling LV, Renshaw D, Cooper D, Leung KY, Perretti M ( 2008 ) . Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles . BLOOD vol. 112 , ( 6 ) 2512 - 2519 .

Cooper D, Norling LV, Perretti M ( 2008 ) . Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow . J Leukoc Biol vol. 83 , ( 6 ) 1459 - 1466 .

Norling LV, Sampaio ALF, Cooper D, Perretti M ( 2008 ) . Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking . FASEB J vol. 22 , ( 3 ) 682 - 690 .

Urquhart P, Rosignoli G, Cooper D, Motterlini R, Perretti M ( 2007 ) . Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow . J PHARMACOL EXP THER vol. 321 , ( 2 ) 656 - 662 .

Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ, Solito E, Perretti M ( 2006 ) . Antiflammin-2 activates the human formyl-peptide receptor like 1 . ScientificWorldJournal vol. 6 , 1375 - 1384 .

Urquhart P, Cooper D, Motterlini R, Perretti M ( 2006 ) . CO-releasing molecules modulate leukocyte/endothelial cell adhesion: under static and flow studies . FASEB JOURNAL . vol. 20 , A1321 - A1321 .

Norling LV, Cooper D, Perretti M ( 2006 ) . Endogenous Galectn-1 inhibits lymphocyte-endothelial cell interactions as determined by small interference RNA . FASEB JOURNAL . vol. 20 , A647 - A647 .

Hayhoe RPG, Cooper D, Perretti M ( 2006 ) . The anti-adhesive effects of Annexin 1 on neutrophil-endothelial interactions under flow . FASEB JOURNAL . vol. 20 , A646 - A646 .

Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D, Perretti M ( 2006 ) . Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement . BLOOD vol. 107 , ( 5 ) 2123 - 2130 .

COOPER D, Stokes KY, Wood KC, Russell J, Granger DN, Petnehazy T ( 2006 ) . Angiotensin II type I receptors and the intestinal microvascular dysfunction induced by ischemia and reperfusion . Am J Physiol Gastrointest Liver Physiol vol. 290 , ( 6 ) G1203 - G1210 .

Perretti M, COOPER D, Gil CD, Oliani SM, Rosignoli G ( 2006 ) . Inflammation-induced modulation of cellular galectin-1 and –3 expression in a model of rat peritonitis . inflammation Research vol. 55 , ( 3 ) 99 - 107 .

Cooper D, Hayhoe RPG, Perretti M ( 2005 ) . Effect of annexin 1 in an in vitro model of human neutrophil-endothelial interaction under flow . FASEB JOURNAL . vol. 19 , A1522 - A1522 .

Cooper D, Perretti M ( 2005 ) . Galectin-1 inhibits neutrophil rolling in a carbohydrate-dependent manner . FASEB JOURNAL . vol. 19 , A1512 - A1512 .

COOPER D, Granger DN, Tailor A ( 2005 ) . Platelet-vessel wall interactions in the microcirculation . Microcirculation vol. 12 , ( 3 ) 275 - 285 .

Paul-Clark MJ, Van Cao T, Moradi-Bidhendi N, Cooper D, Gilroy DW ( 2004 ) . 15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation . J Exp Med vol. 200 , ( 1 ) 69 - 78 .

COOPER D, Granger DN, Williams M, Chitman KC ( 2004 ) . Leukocyte dependence of platelet adhesion in postcapillary venules . AJP Heart and Circulatory Physiology vol. 286 , ( 5 ) H1895 - H1900 .

Ishikawa M, Cooper D, Arumugam TV, Zhang JH, Nanda A, Granger DN ( 2004 ) . Platelet-leukocyte-endothelial cell interactions following midline cerebral artery occlusion and reperfusion . Journal of Cerebral Blood Flow and Metabolism vol. 24 , ( 8 ) 907 - 915 .

COOPER D, Williams M, Granger DN, Chitman KC ( 2003 ) . Time-dependent platelet-vessel wall interactions induced by intestinal ischemia-reperfusion . Am J Physiol Gastrointest Liver Physiol vol. 284 , ( 6 ) G1027 - G1033 .

COOPER D, Ishikawa M, Russell J, Zhang JH, Granger DN, Nanda A, Salter JW ( 2003 ) . Molecular determinants of the prothrombogenic and inflammatory phenotype assumed by the postischemic cerebral microcirculation . Stroke vol. 34 , 1777 - 1782 .

COOPER D, Granger DN, McCord JM, Cerwinka WH, Krieglstein CF, Ross CR ( 2003 ) . Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules . Am J Physiol vol. 284 , H535 - H541 .

COOPER D, Stokes KY, Granger DN, Tailor A ( 2002 ) . Hypercholesterolemia promotes inflammation and microvascular dysfunction: role of nitric oxide and superoxide . Free Radic Biol Med vol. 33 , ( 8 ) 1026 - 1036 .

COOPER D, Granger DN, Stokes KY, Tailor A, Russell JM ( 2002 ) . Low venular shear rates promote leukocyte dependent recruitment of adherent platelets . Am J Physiol vol. 284 , G123 - G129 .

COOPER D, Granger DN, Feelisch M, Cernwinka WH, Krieglstein CF ( 2002 ) . Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules . Am J Physiol vol. 282 , H1111 - H1117 .

COOPER D, Granger DN, Stokes KY, Tailor A ( 2002 ) . Oxidative stress promotes blood cell-endothelial cell interactions in the microcirculation . Cardiovasc Toxicol vol. 2 , 165 - 180 .

Marshall NA, Howe JG, Formica R, Krause D, Wagner JE, Berliner N, Crouch J, Pilip I et al. ( 2000 ) . Rapid reconstitution of Epstein-Barr virus-specific T lymphocytes following allogeneic stem cell transplantation . Blood vol. 96 , ( 8 ) 2814 - 2821 .

Yazici ZA, Behrendt M, Cooper D, Goodfield M, Partridge L, Lindsey NJ ( 2000 ) . The Identification of Endothelial Cell Autoantigens . Journal of Autoimmunity vol. 15 , ( 1 ) 41 - 49 .