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Publications:  Dr Emanuela Carlotti

Murray-Brown W, Carlotti E, Floyd J, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Mehr R et al. (2016). Next-generation sequencing demonstrates dynamic recirculation of B cell clones in ectopic lymphoid structures of Sjogren's syndrome. EUROPEAN JOURNAL OF IMMUNOLOGY. Conference: European League Against Rheumatism vol. 46, 939-940.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16266
Corsiero E, Carlotti E, Prediletto E, Jagemann L, Pitzalis C, Bombardieri M (2016). The role of somatic hypermutation and N-glycosylation in the anti-NET immunoreactivity of RA synovial monoclonal antibodies. EUROPEAN JOURNAL OF IMMUNOLOGY. vol. 46, 116-117.
Carlotti E, Wrench D, Rosignoli G, Marzec J, Sangaralingam A, Hazanov L, Michaeli M, Hallam S et al.(2015). High throughput sequencing analysis of the immunoglobulin heavy chain gene from flow-sorted B cell sub-populations define the dynamics of follicular lymphoma clonal evolution. PLoS ONE vol. 10, (9)
10.1371/journal.pone.0134833
Murray-Brown W, Carlotti E, Floyd J, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Mehr R et al. (2015). Next-Generation Sequencing Demonstrates Dynamic Recirculation of B Cell Clones in Ectopic Lymphoid Structures of Sjogren's Syndrome. SCANDINAVIAN JOURNAL OF IMMUNOLOGY. vol. 81, 401-402.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7753
Corsiero E, Bombardieri M, Carlotti E, Pratesi F, Robinson W, Migliorini P, Pitzalis C(2014). Citrullinated histones from neutrophil extracellular traps (NETs) fuel ectopic germinal centre responses and ACPA production in rheumatoid joints. IMMUNOLOGY vol. 143, 43-43.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6576
Corsiero E, Carlotti E, Pratesi F, Wardemann H, Robinson W, Migliorini P, Pitzalis C, Bombardieri M (2014). MONOCLONAL ANTIBODIES DERIVED FROM SINGLE CD19+SYNOVIAL B CELLS OF RA PATIENTS WITH TERTIARY LYMPHOID STRUCTURES DISPLAY PREFERENTIAL IMMUNOREACTIVITY TOWARDS CITRULLINATED PROTEINS OF NETS. ANNALS OF THE RHEUMATIC DISEASES. vol. 73, 162-162.
10.1136/annrheumdis-2014-eular.4422
Corsiero E, Carlotti E, Wardemann H, Robinson W, Migliorini P, Pratesi F, Pitzalis C, Bombardieri M (2014). MONOCLONAL ANTIBODIES FROM CD19(+) SYNOVIAL B CELLS OF RA PATIENTS WITH TERTIARY LYMPHOID STRUCTURES DISPLAY A STRONG IMMUNOREACTIVITY TOWARDS CITRULLINATED HISTONES FROM NEUTROPHILS NETS. ANNALS OF THE RHEUMATIC DISEASES. vol. 73, A13-A13.
10.1136/annrheumdis-2013-205124.30
Okosun J, Bödör C, Wang J, Araf S, Yang C-Y, Pan C, Boller S, Cittaro D et al.(2014). Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nat Genet vol. 46, (2) 176-181.
10.1038/ng.2856
Corsiero E, Bombardieri M, Carlotti E, Wardemann H, Robinson WH, Pitzalis C (2013). Recombinant Monoclonal Antibodies Derived From Single CD19+Synovial B Cells Of RA Patients With Tertiary Lymphoid Structures Display a Strong Immunoreactivity Towards Citrullinated Histones. ARTHRITIS AND RHEUMATISM. vol. 65, S1127-S1128.
Okosun J, Boedoer C, Wang J, Araf S, Marzec J, Iqbal S, Matthews J, Calaminici M et al. (2012). Whole Genome Sequencing in Sequential Biopsies Reveals the Genetic Evolution of Follicular Lymphoma to Transformed Follicular Lymphoma. BLOOD. vol. 120,
10.1182/blood.V120.21.145.145
Wrench D, Leighton P, Skibola CF, Conde L, Cazier J-B, Matthews J, Iqbal S, Carlotti E et al.(2011). SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma. Blood vol. 117, (11) 3147-3150.
10.1182/blood-2010-10-315382
Wrench D, Sangaralingam A, Tayyib H, Kang MK, Riain C, Gupta M, Carlotti E, Bodor C et al. (2010). TNERSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenviroment In Transformed Follicular Lymphoma. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 349-349.
Wrench D, Sangaralingam A, Tayyib H, Kang MK, Riain C, Gupta M, Carlotti E, Bodor C et al. (2010). TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma. BLOOD. vol. 116, 349-349.
Wrench J, Skibola C, Matthews J, Cazier JB, Iqbal S, Carlotti E, Calaminici M, Davies A et al. (2010). SNP RS6457327 ON CHROMOSOME 6P PREDICTS TRANSFORMATION OF FOLLICULAR LYMPHOMA. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 170-171.
Carlotti E, Gribben JG(2009). Stem cell mimicry: key to transformation?. Blood vol. 114, (15) 3133-3134.
10.1182/blood-2009-08-236786
Carlotti E, Wrench D, Matthews J, Iqbal S, Davies A, Norton A, Hart J, Lai R et al.(2009). Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone. Blood vol. 113, (15) 3553-3557.
10.1182/blood-2008-08-174839
Wrench D, Waters R, Carlotti E, Iqbal S, Matthews J, Calaminici M, Gribben J, Lister TA et al.(2009). Clinical relevance of MDM2 SNP 309 and TP53 Arg72Pro in follicular lymphoma. Haematologica vol. 94, (1) 148-150.
10.3324/haematol.13533
O'Shea D, O'Riain C, Taylor C, Waters R, Carlotti E, MacDougall F, Gribben J, Rosenwald A et al.(2008). The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival. BLOOD vol. 112, (8) 3126-3129.
10.1182/blood-2008-05-154013
Wrench D, Waters R, Matthews J, Calaminici M, Carlotti E, Iqbal S, Gribben J, Lister A et al. (2008). MDM2 309 and TP53 ARG72PRO SNP genotypes do not predict clinical outcome of follicular lymphoma. ANNALS OF ONCOLOGY. vol. 19, 178-178.
Pulsoni A, Della Starza I, Frattarelli N, Carlotti E, Cavalieri E, Ghia E, Matturro A, De Angelis F et al. (2008). PCR for BCL-2/IGH+ cells in stage I/II follicular lymphoma identifies positive cells in bone marrow and peripheral blood of the majority of patients, that can be cleared by lymph node irradiation. ANNALS OF ONCOLOGY. vol. 19, 179-179.
O'Shea D, O'Riain C, Taylor C, Waters R, Carlotti E, MacDougall F, Gribben J, Rosenwald A et al. (2008). TP53 MUTATION IDENTIFIES A HIGH RISK GROUP OF PATIENTS AT DIAGNOSIS OF FOLLICULAR LYMPHOMA AND IS ASSOCIATED WITH SHORTER TIME TO DISEASE PROGRESSION AND OVERALL SURVIVAL. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 93, 356-356.
Carlotti E, Wrench D, Iqbal S, O'Shea D, Davies A, Virappane P, Hart J, Lai R et al. (2007). Determining the mechanism of transformation of follicular lymphoma into diffuse large B cell lymphoma. BLOOD. vol. 110, 61A-61A.
Carlotti E, Salmoiraghi S, Palumbo GA, Oldani E, Tibullo D, Rossi A, Golay J, Pulsoni A et al. (2007). Fc alpha RIIIA and Fc Gamma RIIA polymorphisms do not predict the clinical outcome of follicular non Hodgkin's lymphoma patients treated with sequential CHOP and Rituximab. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 49-49.
Carlotti E, Palumbo GA, Oldani E, Tibullo D, Salmoiraghi S, Rossi A, Golay J, Pulsoni A et al.(2007). FcgammaRIIIA and FcgammaRIIA polymorphisms do not predict clinical outcome of follicular non-Hodgkin's lymphoma patients treated with sequential CHOP and rituximab. Haematologica vol. 92, (8) 1127-1130.
10.3324/haematol.11288
Fitzgibbon J, Iqbal S, Davies A, O'shea D, Carlotti E, Chaplin T, Matthews J, Raghavan M et al.(2007). Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma. Leukemia vol. 21, (7) 1514-1520.
10.1038/sj.leu.2404696
Pulsoni A, Della Starza I, Frattarelli N, Ghia E, Carlotti E, Cavalieri E, Matturro A, Tempera S et al. (2007). Localized follicular lymphoma: Spread of BCL-2/IgH+ cells in the blood and bone marrow from the primary site of disease and possibility of clearance after involved field radiotherapy. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 103-103.
O'Shea D, Iqbal S, Carlotti E, Davies A, Chaplin T, Matthews J, Manoj M, Norton A et al. (2007). SNP array profiling of follicular lymphoma reveals novel regions of acquired UPD. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 62-62.
Pulsoni A, Della Starza I, Frattarelli N, Ghia E, Carlotti E, Cavalieri E, Matturro A, Tempera S et al.(2007). Stage I/II follicular lymphoma: spread of bcl-2/IgH+ cells in blood and bone marrow from primary site of disease and possibility of clearance after involved field radiotherapy. BRIT J HAEMATOL vol. 137, (3) 216-220.
10.1111/j.1365-2141.2007.06545.x
O'Shea D, Iqbal S, Carlotti E, Davies A, Chaplin T, Matthews J, Raghavan M, Norton A et al. (2006). aUPD in the clonal evolution of follicular lymphoma. BLOOD. vol. 108, 585A-585A.
10.1182/blood.v108.11.2065.2065
Carlotti E, Palumbo GA, Oldani E, Acerboni S, Di Raimondo F, Cortelazzo S, Pulsoni A, Barbui T et al. (2005). Bone marrow BCL2/IgH+ cells at diagnosis and not FCGRIIIA polymorphism predict response in follicular non-Hodgkin's lymphoma patients treated with sequential CHOP and rituximab. BLOOD. vol. 106, 289A-290A.
Cortelazzo S, Rossi A, Carlotti E, Viero P, Rambaldi A, Barbui T (2005). The addition of Rituximab to high dose sequential chemotherapy (HDS) programs with autologous transplantation significantly improves the outcome of patients with refractory or relapsed B-cell non Hogkin's lymphoma. BLOOD. vol. 106, 589A-590A.
10.1182/blood.V106.11.2084.2084
Rambaldi A, Carlotti E, Oldani E, Della Starza I, Baccarani M, Cortelazzo S, Lauria F, Arcaini L et al.(2005). Quantitative PCR of bone marrow BCL2/IgH+ cells at diagnosis predicts treatment response and long-term outcome in follicular non-Hodgkin lymphoma. Blood vol. 105, (9) 3428-3433.
10.1182/blood-2004-06-2490
Rambaldi A, Carlotti E, Baccarani M, Barbui T, Lauria F, Lazzarino M, Mandelli F, Morra E et al. (2003). Long term improvement of clinical outcome of follicular lymphoma patients achieving a molecular response after sequential CHOP and rituximab treatment: Predictive value of real time quantitative PCR to identify responding patients. BLOOD. vol. 102, 409A-409A.
Carlotti E, Pettenella F, Amaru R, Slater S, Lister TA, Barbui T, Basso G, Cazzaniga G et al.(2002). Molecular characterization of a new recombination of the SIL/TAL-1 locus in a child with T-cell acute lymphoblastic leukaemia. BRIT J HAEMATOL vol. 118, (4) 1011-1018.
10.1046/j.1365-2141.2002.03747.x
Rambaldi A, Lazzari M, Manzoni C, Carlotti E, Arcaini L, Baccarani M, Barbui T, Bernasconi C et al.(2002). Monitoring of minimal residual disease after CHOP and rituximab in previously untreated patients with follicular lymphoma. BLOOD vol. 99, (3) 856-862.
10.1182/blood.v99.3.856
Rambaldi A, Carlotti E, Baccarani M, Barbui T, Dastoli G, Lauria F, Lazzarino M, Mandelli F et al.(2001). Monitoring of minimal residual disease after CHOP and Rituximab in previously untreated follicular lymphoma patients. BLOOD vol. 98, (11) 603A-603A.
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