Publications: Prof Claude Chelala
Barclay NL, Burn E, Delmestri A, Duarte-Salles T, Golozar A, Man WY, Tan EH, Tietzova I et al.
(
2024
)
.
Trends in incidence, prevalence, and survival of breast cancer in the United Kingdom from 2000 to 2021
.
Scientific Reports
vol.
14
,
(
1
)
Ang A, Michaelides A, Chelala C, Ullah D, Kocher HM, Bank BPT
(
2024
)
.
Prognostication for recurrence patterns after curative resection for pancreatic ductal adenocarcinoma
.
Annals of Hepato-Biliary-Pancreatic Surgery
vol.
0
,
(
0
)
248
-
261
.
Ahmad TA, Dayem Ullah AZ, Chelala C, Gopal DP, Eto F, Henkin R, Samuel M, Finer S et al.
(
2024
)
.
Prevalence of multimorbidity in survivors of 28 cancer sites: an English nationwide cross-sectional study
.
American Journal of Cancer Research
vol.
14
,
(
2
)
880
-
896
.
Ahmad TA, Gopal DP, Chelala C, Dayem Ullah AZ, Taylor SJ
(
2023
)
.
Multimorbidity in people living with and beyond cancer: a scoping review
.
American Journal of Cancer Research
vol.
13
,
(
9
)
4346
-
4365
.
Baleeiro RB, Liu P, Dunmall LSC, Di Gioia C, Nagano A, Cutmore L, Wang J, Chelala C et al.
(
2023
)
.
Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancer
.
Journal for ImmunoTherapy of Cancer
vol.
11
,
(
8
)
Pires MAF, Chelala CMDSCF, Chelala CA
(
2023
)
.
Desestruturação da produção de soja na fronteira amazônica: o caso do estado do Amapá
.
Revista de Gestão e Secretariado (Management and Administrative Professional Review)
vol.
14
,
(
6
)
9700
-
9716
.
Chelala C, Costello-Goldring E
(
2023
)
.
Chairwomen: Diagnostic studies for pancreatic cancer
.
Pancreatology
vol.
23
,
(
4
)
Phillips MM, Pavlyk I, Allen M, Ghazaly E, Cutts R, Carpentier J, Berry JS, Nattress C et al.
(
2023
)
.
Correction: A role for macrophages under cytokine control in mediating resistance to ADI-PEG20 (pegargiminase) in ASS1-deficient mesothelioma
.
Pharmacological Reports
vol.
75
,
(
3
)
753
-
753
.
Chelala CMDSCF, Chelala CA
(
2023
)
.
AGRONEGÓCIOS E MUDANÇAS CLIMÁTICAS: REFLEXÕES SOBRE OS CONFLITOS SOCIOAMBIENTAIS BRASILEIROS
.
Terceira Margem Amazônia
vol.
8
,
(
19
)
35
-
55
.
Latreille J, Thorn G, Jdid R, Gendronneau G, Tabara Y, Harada Y, Forestier S, Chelala C et al.
(
2023
)
.
541 Gene set enrichment analysis identifies biological networks associated with skin aging in a large Japanese population: Data from the Nagahama cohort
.
Journal of Investigative Dermatology
vol.
143
,
(
5
)
Oscanoa J, Latreille J, Le Clerc S, Muther C, Thorn G, Gendronneau G, Matsuda F, Forestier S et al.
(
2023
)
.
902 Development of a web-based platform to facilitate research to uncover the skin ageing mechanism
.
Journal of Investigative Dermatology
vol.
143
,
(
5
)
Phillips MM, Pavlyk I, Allen M, Ghazaly E, Cutts R, Carpentier J, Berry JS, Nattress C et al.
(
2023
)
.
A role for macrophages under cytokine control in mediating resistance to ADI-PEG20 (pegargiminase) in ASS1-deficient mesothelioma
.
Pharmacological Reports
vol.
75
,
(
3
)
570
-
584
.
Abdollahyan M, Gadaleta E, Asif M, Oscanoa J, Barrow-McGee R, Jones S, Jones LJ, Chelala C
(
2023
)
.
Dynamic Biobanking for Advancing Breast Cancer Research
.
Journal of Personalized Medicine
vol.
13
,
(
2
)
Oscanoa J, Latreille J, Le Clerc S, Muther C, Thorn G, Gendronneau G, Matsuda F, Forestier S et al.
(
2023
)
.
Development of a web-based platform to facilitate research to uncover the skin ageing mechanism
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
S154
-
S154
.
Latreille J, Thorn G, Jdid R, Gendronneau G, Tabara Y, Harada Y, Forestier S, Chelala C et al.
(
2023
)
.
Gene set enrichment analysis identifies biological networks associated with skin aging in a large Japanese population: Data from the Nagahama cohort
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
S93
-
S93
.
Zardab M, Balarajah V, Banerjee A, Stasinos K, Saad A, Imrali A, Hughes C, Roberts R et al.
(
2022
)
.
Differentiating Ductal Adenocarcinoma of the Pancreas from Benign Conditions Using Routine Health Records: A Prospective Case-Control Study
.
Cancers
vol.
15
,
(
1
)
Wu H, Wang M, Wu J, Francis F, Chang Y-H, Shavick A, Dong H, Poon MTC et al.
(
2022
)
.
A survey on clinical natural language processing in the United Kingdom from 2007 to 2022
.
npj Digital Medicine
vol.
5
,
(
1
)
Sivapalan L, Kocher HM, Ross-Adams H, Chelala C
(
2022
)
.
The molecular landscape of pancreatic ductal adenocarcinoma
.
Pancreatology
vol.
22
,
(
7
)
925
-
936
.
Baleeiro RB, Bouwens CJ, Liu P, Di Gioia C, Dunmall LSC, Nagano A, Gangeswaran R, Chelala C et al.
(
2022
)
.
MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy
.
OncoImmunology
vol.
11
,
(
1
)
Gadaleta E, Thorn GJ, Ross‐Adams H, Jones LJ, Chelala C
(
2022
)
.
Field cancerization in breast cancer
.
The Journal of Pathology
vol.
257
,
(
4
)
561
-
574
.
Speirs V, Cox A, Chelala C, James JA, Adams RA, Jones JL
(
2022
)
.
A biobank perspective on use of tissue samples donated by trial participants
.
The Lancet Oncology
vol.
23
,
(
5
)
Dawoud MM, Jones DT, Chelala C, Abdou AG, Dreger SA, Asaad N, El-Wahed MA, Jones L
(
2022
)
.
Expression Profile of Myoepithelial Cells in DCIS: Do They Change From Protective Angels to Wicked Witches?
.
Applied Immunohistochemistry & Molecular Morphology
vol.
30
,
(
6
)
397
-
409
.
Sivapalan L, Thorn GJ, Gadaleta E, Kocher HM, Ross-Adams H, Chelala C
(
2022
)
.
Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer
.
BMC Cancer
vol.
22
,
(
1
)
Dayem Ullah AZM, Stasinos K, Chelala C, Kocher HM
(
2021
)
.
Temporality of clinical factors associated with pancreatic cancer: a case-control study using linked electronic health records
.
BMC Cancer
vol.
21
,
(
1
)
Keane L, Antignano I, Riechers S-P, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J et al.
(
2021
)
.
mTOR-dependent translation amplifies microglia priming in aging mice
.
Journal of Clinical Investigation
vol.
131
,
(
20
)
Lu S, Zhang Z, Du P, Chard LS, Yan W, El Khouri M, Wang Z, Zhang Z et al.
(
2021
)
.
Correction: A Virus-infected, Reprogrammed Somatic Cell–derived Tumor Cell (VIReST) Vaccination Regime can Prevent Initiation and Progression of Pancreatic Cancer
.
Clinical Cancer Research
vol.
27
,
(
9
)
2663
-
2663
.
Allen N, Allen M, Gomm J, Nelan R, Nagano A, Chelala C, Jones L
(
2021
)
.
P020. Defining molecular signatures to personalise management of patients with early breast cancer
.
European Journal of Surgical Oncology
.
vol.
47
,
Ullah AZMD, Sivapalan L, Kocher HM, Chelala C
(
2021
)
.
COVID-19 in patients with hepatobiliary and pancreatic diseases: a single-centre cross-sectional study in East London
.
BMJ Open
vol.
11
,
(
4
)
Marzec J, Ross-Adams H, Pirrò S, Wang J, Zhu Y, Mao X, Gadaleta E, Ahmad AS et al.
(
2021
)
.
The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis
.
Cancers
vol.
13
,
(
2
)
Sivapalan L, Thorn G, Gadaleta E, Kocher H, Ross-Adams H, Chelala C
(
2021
)
.
Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer
.
Borakati A, Stasinos K, Ullah D, Chelala C, Kocher H
(
2021
)
.
Effect of Diabetes Mellitus on Survival in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-analysis
.
Hepato Pancreato Biliary
vol.
23
,
s682
-
s683
.
Oscanoa J, Sivapalan L, Abdollahyan M, Gadaleta E, Chelala C
(
2021
)
.
SNPnexus COVID: Facilitating the Analysis of COVID-19 Host Genetics
.
Archives of Clinical and Biomedical Research
vol.
05
,
(
05
)
Sivapalan L, Kocher HM, Ross-Adams H, Chelala C
(
2020
)
.
Molecular profiling of ctDNA in pancreatic cancer: Opportunities and challenges for clinical application
.
Pancreatology
vol.
21
,
(
2
)
363
-
378
.
Ullah AD, Kocher H, Chelala C
(
2020
)
.
COVID-19 in patients with hepatobiliary and pancreatic diseases in East London: a single-centre cohort study
.
Pancreatology
vol.
20
,
(
8
)
Ullah D, Kocher H, Chelala C
(
2020
)
.
Data integration for patient benefit
.
Pancreatology
vol.
20
,
(
8
)
Imrali A, Hughes CS, Coetzee AS, Delvecchio FR, Saad A, Roberts R, Chelala C, ChinAleong J et al.
(
2020
)
.
Validation of a Novel, Flash‐Freezing Method: Aluminum Platform
.
Current Protocols Essential Laboratory Techniques
vol.
21
,
(
1
)
Ullah AZMD, Sivapalan L, Kocher HM, Chelala C
(
2020
)
.
COVID-19 in patients with hepatobiliary and pancreatic diseases: A single-centre cross-sectional study in East London
.
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al.
(
2020
)
.
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer
.
npj Breast Cancer
vol.
6
,
(
1
)
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al.
(
2020
)
.
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer
.
NPJ Breast Cancer
vol.
6
,
(
1
)
Xu R, Jones W, Wilcz‐Villega E, Costa AS, Rajeeve V, Bentham RB, Bryson K, Nagano A et al.
(
2020
)
.
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism
.
EMBO Reports
vol.
21
,
(
9
)
Oscanoa J, Sivapalan L, Gadaleta E, Ullah AZD, Lemoine NR, Chelala C
(
2020
)
.
SNPnexus: a web server for functional annotation of human genome sequence variation (2020 update)
.
Nucleic Acids Research
vol.
48
,
(
W1
)
Montero Melendez T, Nagano A, Chelala C, Filer A, Buckley CD, Perretti M
(
2020
)
.
Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
.
Nature Communications
vol.
11
,
(
1
)
Article
745
,
Lu S, Zhang Z, Du P, Chard LS, Yan W, Khouri ME, Wang Z, Zhang Z et al.
(
2020
)
.
A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer
.
Clinical Cancer Research
vol.
26
,
(
2
)
465
-
476
.
Pirrò S, Spada F, Gadaleta E, Ferrentino F, Thorn GJ, Cesareni G, Chelala C
(
2019
)
.
HiPPO and PANDA: Two Bioinformatics Tools to Support Analysis of Mass Cytometry Data
.
J Comput Biol
Martin S
(
2019
)
.
MLH1 deficiency leads to deregulated mitochondrial metabolism
.
Cell Death and Disease
vol.
10
,
795
-
795
.
Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB et al.
(
2019
)
.
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy
.
The Journal of Pathology
vol.
249
,
(
3
)
332
-
342
.
Pirrò S, Gadaleta E, Galgani A, Colizzi V, Chelala C
(
2019
)
.
SMAC, a computational system to link literature, biomedical and expression data
.
Scientific Reports
vol.
9
,
(
1
)
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.
(
2019
)
.
Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma
.
Leukemia
vol.
33
,
(
6
)
1540
-
1540
.
Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C et al.
(
2019
)
.
Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors
.
Oncogene
vol.
38
,
(
27
)
5381
-
5395
.
Allen N, Allen M, Ahmed K, Gomm J, Nelan R, Nagano A, Chelala C, Gadaleta E et al.
(
2019
)
.
Defining molecular signatures to personalise management of patients with early breast cancer
.
CANCER RESEARCH
.
Conference:
2018 San Antonio Breast Cancer Symposium
from:
04/12/2019
to:
08/12/2019
,
vol.
79
,
Inman GJ, Wang J, Nagano A, Alexandrov LB, Purdie KJ, Taylor RG, Sherwood V, Thomson J et al.
(
2018
)
.
The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature
.
Nature Communications
vol.
9
,
(
1
)
Arnandis T, Monteiro P, Adams SD, Bridgeman VL, Rajeeve V, Gadaleta E, Marzec J, Chelala C et al.
(
2018
)
.
Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion
.
Developmental Cell
vol.
47
,
(
4
)
409
-
424.e9
.
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A et al.
(
2018
)
.
A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia
.
EMBO Mol Med
Bladen JC, Wang J, Sangaralingam A, Moosajee M, Fitchett C, Chelala C, Beaconsfield M, O’Toole EA et al.
(
2018
)
.
MicroRNA and transcriptome analysis in periocular Sebaceous Gland Carcinoma
.
Scientific Reports
vol.
8
,
(
1
)
Dayem Ullah AZ, Oscanoa J, Wang J, Nagano A, Lemoine NR, Chelala C
(
2018
)
.
SNPnexus: assessing the functional relevance of genetic variation to facilitate the promise of precision medicine
.
Nucleic Acids Research
vol.
46
,
(
W1
)
w109
-
w113
.
Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker A-M, Kapitonova E, Bakhouche BA, Tanner Y et al.
(
2018
)
.
PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer
.
Cell Reports
vol.
22
,
(
9
)
2469
-
2481
.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.
(
2018
)
.
Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma
.
Leukemia
vol.
32
,
(
5
)
1261
-
1265
.
WANG Y, Dayem Ullah AZ, Chelala C
(
2018
)
.
IW-Scoring: an Integrative Weighted Scoring framework for annotating and prioritising genetic variations in the noncoding genome. Nucleic Acids Research
.
Nucleic Acids Research
vol.
46
,
(
8
)
e47
-
e47
.
Wang J, Dayem Ullah AZ, Chelala C
(
2018
)
.
IW-Scoring: an Integrative Weighted Scoring framework for annotating and prioritizing genetic variations in the noncoding genome
.
Nucleic Acids Research
vol.
46
,
(
8
)
e47
-
e47
.
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al.
(
2017
)
.
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers
.
Cancer Discov
Barry S, Solomou A, Vignola L, Collier D, Carlsen E, Gadaleta E, Berney DM, Chelala C et al.
(
2017
)
.
A comprehensive analysis of the AIP mutation positive pituitary tumour microenvironment: role of stromal cells and the pro-inflammatory cytokine network
.
Endocrine Abstracts
Marzec J, Dayem Ullah AZ, Pirrò S, Gadaleta E, Crnogorac-Jurcevic T, Lemoine NR, Kocher HM, Chelala C
(
2017
)
.
The Pancreatic Expression Database: 2018 update
.
Nucleic Acids Res
vol.
46
,
(
D1
)
D1107
-
D1110
.
Gadaleta E, Pirrò S, Ullah AZD, Marzec J, Chelala C
(
2017
)
.
BCNTB bioinformatics: the next evolutionary step in the bioinformatics of breast cancer tissue banking
.
Nucleic Acids Research
vol.
46
,
(
Database issue
)
Sangaralingam A, Dayem Ullah AZ, Marzec J, Gadaleta E, Nagano A, Ross-Adams H, Wang J, Lemoine NR et al.
(
2017
)
.
'Multi-omic' data analysis using O-miner
.
Brief Bioinform
Chupin J, Nagano A, Haley V, Lenihan C, Cavicchioli F, O’Leary K, Sahgal N, Nigro CL et al.
(
2017
)
.
Abstract 104: miRNAs in the 14q32 cluster are involved in lapatinib resistance
.
Cancer Research
.
vol.
77
,
104
-
104
.
Wang J, Dumartin L, Mafficini A, Ulug P, Sangaralingam A, Alamiry NA, Radon TP, Salvia R et al.
(
2017
)
.
Splice variants as novel targets in pancreatic ductal adenocarcinoma
.
Scientific Reports
vol.
7
,
(
1
)
Tawana K, Wang J, Király PA, Kállay K, Benyó G, Zombori M, Csomor J, Al Seraihi A et al.
(
2017
)
.
Recurrent somatic JAK-STAT pathway variants within a RUNX1-mutated pedigree
.
European Journal of Human Genetics
vol.
25
,
(
8
)
1020
-
1024
.
Ironside A, Hawkesford K, Gomm J, Haywood L, Goulding I, Wang J, Lamaziere A, Poirot M et al.
(
2017
)
.
Molecular mediators of mammographic density
.
CANCER RESEARCH
.
Conference:
2016 San Antonio Breast Cancer Symposium
from:
06/12/2016
to:
10/12/2016
,
vol.
77
,
Morrissey B, Blyth K, Carter P, Chelala C, Jones L, Holen I, Speirs V
(
2017
)
.
The Sharing Experimental Animal Resources, Coordinating Holdings (SEARCH) Framework: Encouraging Reduction, Replacement, and Refinement in Animal Research
.
PLoS Biol
vol.
15
,
(
1
)
e2000719
-
e2000719
.
Moniz LS, Surinova S, Ghazaly E, Velasco LG, Haider S, Rodríguez-Prados JC, Berenjeno IM, Chelala C et al.
(
2017
)
.
Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate
.
Scientific Reports
vol.
7
,
(
1
)
Besley C, Kotsiou E, Petty R, Sangaralingam A, Chelala C, Ghazaly E, LeDieu R, Gribben J et al.
(
2017
)
.
ALLORESPONSES OF HUMAN T-CELLS FROM ADULT PERIPHERAL BLOOD AND UMBILICAL CORD BLOOD ARE DIFFERENTIALLY IMPACTED BY LENALIDOMIDE - IMPLICATIONS FOR AHSCT
.
HAEMATOLOGICA
.
vol.
102
,
638
-
638
.
Harwood C, Proby C, Wang J, Nagano A, Alexandrov L, Purdie K, Chelala C, Inman G et al.
(
2017
)
.
Chronic azathioprine treatment is causal in cutaneous squamous cell carcinoma development and is associated with a novel mutational signature
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
177
,
9
-
10
.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward JA et al.
(
2017
)
.
Genomic Profiling Reveals Spatial Intra-Tumor Heterogeneity in Follicular Lymphoma
.
BLOOD
.
vol.
130
,
Thomson J, Wang A, Nagano A, Chelala C, Purdie K, Har C, Proby C, Inman G et al.
(
2017
)
.
Understanding actinic keratosis and squamous cell carcinoma in the era of whole-exome and -genome sequencing
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
177
,
15
-
16
.
Besley C, Kotsiou E, Petty R, Ajanthah S, Chelala C, Ghazaly E, Le Dieu R, Davies J et al.
(
2016
)
.
Alloresponses of Human T-Cells from Adult Peripheral Blood and Umbilical Cord Blood Are Differentially Impacted By Lenalidomide
.
Blood
.
vol.
128
,
Makoukji J, Makhoul NJ, Khalil M, El-Sitt S, Aldin ES, Jabbour M, Boulos F, Gadaleta E et al.
(
2016
)
.
Gene expression profiling of breast cancer in Lebanese women
.
Scientific Reports
vol.
6
,
36639
-
36639
.
Ghayad SE, Rammal G, Ghamloush F, Basma H, Nasr R, Diab-Assaf M, Chelala C, Saab R
(
2016
)
.
Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts
.
Scientific Reports
vol.
6
,
Article
37088
,
Parker H, Rose-Zerilli MJJ, Larrayoz M, Clifford R, Edelmann J, Blakemore S, Gibson J, Wang J et al.
(
2016
)
.
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
.
LEUKEMIA
vol.
30
,
(
11
)
2179
-
2186
.
Shaid M, Barry S, Gadaleta E, Chelala C, Korbonits M
(
2016
)
.
The clinical, pathological and molecular differences between sparsely and densely granulated somatotroph adenomas
.
Endocrine Abstracts
Barry S, Carlsen E, Gadaleta E, Berney D, Chelala C, Crnogorac-Jurcevic T, Korbonits M
(
2016
)
.
The role of the microenvironment in the invasive phenotype of familial pituitary tumours
.
Endocrine Abstracts
Speirs V, Morrisey B, Holen I, Blyth K, Carter P, Chelala C, Jones L
(
2016
)
.
SEARCHBreast: An online resource designed to increase the efficiency of using materials derived from breast cancer studies in animals
.
Journal of Pathology
vol.
240
,
(
1
)
120
-
120
.
Mao X, Luo F, Boyd LK, Zhou B, Zhang Y, Stankiewicz E, Marzec J, Vasiljevic N et al.
(
2016
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