Publications:  Dr Anissa Chikh

Issitt T, Bosseboeuf E, De Winter N, Dufton N, Gestri G, Senatore V, Chikh A, Randi AM et al.(2019). Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress. iScience vol. 11, 205-223.

Arcidiacono P, Webb CM, Brooke MA, Zhou H, Delaney PJ, Ng K-E, Blaydon DC, Tinker A et al.(2018). p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response. Nat Commun vol. 9, (1)

Arcidiacono P, Webb CM, Blaydon D, Chikh A, Kelsell DP (2017). iRHOM2-p63 pathway mediates survival and redox balance in keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 137, S207-S207.

Raimondi C, Chikh A, Wheeler AP, Maffucci T, Falasca M(2017). Correction: A novel regulatory mechanism links PLCγ1 to PDK1. J Cell Sci vol. 130, (5)

Maruthappu T, Chikh A, Fell B, Delaney PJ, Brooke MA, Levet C, Moncada-Pazos A, Ishida-Yamamoto A et al.(2017). Rhomboid family member 2 Regulates cytoskeletal stress associated Keratin 16. Nature Communications vol. 8, 14174-14174.

Chikh A, Maruthappu T, Kelsell DP (2016). iRHOM2 regulates Keratin 16, a Major Cytoskeletal Stress Keratin. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S182-S182.

Arcidiacono P, Chikh A, Kelsell DP (2016). p63 regulation of the iRHOM2/ADAM17 pathway in keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S257-S257.

Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP et al.(2016). Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol vol. 136, (7) 1460-1470.

Arcidiacono P, Chikh A, Kelsell D (2016). Regulation of the iRhom2/ADAM17 pathway in keratinocytes. BRITISH JOURNAL OF DERMATOLOGY. vol. 174, E44-E45.

Chikh A, Ferro R, Abbott JJ, Piñeiro R, Buus R, Iezzi M, Ricci F, Bergamaschi D et al.(2016). Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression. Oncotarget vol. 7, (14) 18325-18345.

Fell B, Maruthappu T, Chikh A, Kelsell D (2015). In vitro Organotypic Wound Healing Model: the Role of iRHOM2 in Tylosis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S45-S45.

Maruthappu T, Chikh A, Kelsell D (2015). iRhom2: a novel regulator of wound healing and cancer. BRITISH JOURNAL OF DERMATOLOGY. vol. 172, E39-E40.

Maruthappu T, Chikh A, Kelsell D (2014). iRhom2: a novel regulator of wound healing. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S98-S98.

Raimondi C, Fantin A, Lampropoulou A, Denti L, Chikh A, Ruhrberg C(2014). Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. J Exp Med vol. 211, (6) 1167-1183.

Chikh A, Sanza P, Raimondi C, Akinduro O, Warnes G, Chiorino G, Byrne C, Harwood CA et al.(2014). IASPP is a novel autophagy mudulator in keratinocytes. J Cell Science (advance online edition)

Chikh A, Brooke M, Etheridge S, Kelsell D (2014). Dissecting the regulation of the inactive rhomboid protein 2/ADAM17 pathway in keratinocyte differentiation and barrier function. BRITISH JOURNAL OF DERMATOLOGY. vol. 170, E39-E40.

Akinduro O, Sully K, Chikh A, O'shaughnessy RF, Bergamaschi D, Harwood CA, Philpott MP, Byrne C (2013). Constitutive autophagy as a terminal differentiation mechanism. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S127-S127.

Chikh A, Harwood C, Bergamaschi D (2013). IASPP is a novel autophagy inhibitor in keratinocytes. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S126-S126.

Matin RN, Chikh A, Chong SLP, Mesher D, Graf M, Sanza' P, Senatore V, Scatolini M et al.(2013). p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis. J Exp Med vol. 210, (3) 581-603.

Matin RN, Chikh A, Chong SLP, Harwood C, Bergamaschi D (2012). p63, a p53 repressor in melanoma which confers chemoresistance and a poor prognosis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S127-S127.

Raimondi C, Chikh A, Wheeler AP, Maffucci T, Falasca M(2012). A novel regulatory mechanism links PLCγ1 to PDK1. J Cell Sci vol. 125, (Pt 13) 3153-3163.

Matin RN, Chikh A, Law S, Harwood CA, Bergamaschi D (2012). p63, an alternative p53 repressor in melanoma which confers chemoresistance and a poor prognosis. BRITISH JOURNAL OF DERMATOLOGY. vol. 167, 11-12.

Matin RN, Chikh A, Law S, Harwood CA, Bergamaschi D (2012). p63, an alternative p53 repressor in melanoma which confers chemoresistance and a poor prognosis. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e15-e15.

Chikh A, Matin RNH, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M et al.(2011). iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia. EMBO J vol. 30, (20) 4261-4273.

Chikh A, Bergamaschi D (2011). iASPP mediates regulation of autophagy in keratinocytes. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 914-914.

Chikh A, Bergamaschi D (2011). iASPP/p63 auto-regulatory feedback loop is essential for epithelial integrity and autophagy. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 131, S56-S56.

Chikh A, Matin R, Harwood CA, Bergamaschi D (2010). iASPP: a novel and essential key regulator of skin homeostasis. BRITISH JOURNAL OF DERMATOLOGY. vol. 162, 914-914.

Matin RN, Chikh A, Warnes G, Proby CM, Leigh IM, Harwood CA, Bergamaschi D (2010). p63 is implicated in apoptotic dysregulation in melanoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 162, 921-921.

Chikh A, Bergamaschi D (2009). A novel Role of iASPP, a key regulator in skin development. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 129, S57-S57.

Matin R, Hajji N, Chikh A, Harwood CA, Bergamaschi D (2008). P63 is implicated in apoptotic deregulation in melanoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 158, 911-912.

Chikh A, Sayan E, Thibaut S, Lena AM, DiGiorgi S, Bernard BA, Melino G, Candi E(2007). Expression of GATA-3 in epidermis and hair follicle: relationship to p63. Biochem Biophys Res Commun vol. 361, (1) 1-6.

Ponassi R, Terrinoni A, Chikh A, Rufini A, Lena AM, Sayan BS, Melino G, Candi E(2006). p63 and p73, members of the p53 gene family, transactivate PKCdelta. Biochem Pharmacol vol. 72, (11) 1417-1422.

Candi E, Terrinoni A, Rufini A, Chikh A, Lena AM, Suzuki Y, Sayan BS, Knight RA et al.(2006). p63 is upstream of IKK alpha in epidermal development. J Cell Sci vol. 119, (Pt 22) 4617-4622.

Belfield H, Chikh A, Ramadan S(2005). Apoptosis methods and protocols (vol 12, pg 834, 2005). CELL DEATH DIFFER vol. 12, (10) 1361-1361.

MARUTHAPPU T, CHIKH A, FELL B, DELANEY PJ, BROOKE MA, LEVET C, MONCADA-PAZOS A, ISHIDA-YAMAMOTO A et al.. Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16. Nature Communications