Publications:  Dr Xuenong Bo

Guijarro-Belmar A, Viskontas M, Wei Y, Bo X, Shewan D, Huang W(2019). Epac2 elevation reverses inhibition by chondroitin sulfate proteoglycans in vitro and transforms post-lesion inhibitory environment to promote axonal outgrowth in an ex vivo model of spinal cord injury. J Neurosci

Bo X(2018). Is ATP a key player in conditioning neurons to support axonal regeneration?. Neural Regen Res vol. 13, (12) 2077-2079.

BO X, GUSHCHINA S, PRYCE G, YIP P, Wu D, PALLIER P, GIOVANNONI G, BAKER D(2018). Increased expression of colony-stimulating factor-1 in mouse spinal cord with experimental autoimmune encephalomyelitis correlates with microglial activation and neuronal loss. Glia

BO XUENONG, GUSHCHINA S, PRYCE G, YIP P, WU D, PALLIER P, GIOVANNONI G, BAKER D(2018). Increased expression of colony‐stimulating factor‐1 in mouse spinal cord with experimental autoimmune encephalomyelitis correlates with microglial activation and neuronal loss. Glia vol. 66, (10) 2108-2125.

Wu D, Lee S, Luo J, Xia H, Gushchina S, Richardson PM, Yeh J, Krügel U et al.(2017). Intraneural injection of ATP stimulates regeneration of primary sensory axons in the spinal cord. Journal of Neuroscience vol. 38, (6) 1351-1365.

BO X, Verhaagen J(2015). Gene Delivery and Therapy for Neurological Disorders. Gene Delivery and Therapy for Neurological Disorders, Editors: BO, X, vol. 98, Humana Press

Luo J, Lee S, Wu D, Yeh J, Ellamushi H, Wheeler AP, Warnes G, Zhang Y et al.(2013). P2X7 purinoceptors contribute to the death of Schwann cells transplanted into the spinal cord. Cell Death Dis vol. 4,

Zhang Y, Gao F, Wu D, Moshayedi P, Zhang X, Ellamushi H, Yeh J, Priestley JV et al.(2013). Lentiviral mediated expression of a NGF-soluble Nogo receptor 1 fusion protein promotes axonal regeneration. Neurobiol Dis vol. 58, 270-280.

Bo X, Wu D, Yeh J, Zhang Y(2011). Gene therapy approaches for neuroprotection and axonal regeneration after spinal cord and spinal root injury. Curr Gene Ther vol. 11, (2) 101-115.

Miao T, Wu D, Wheeler A, Wang P, Zhang Y, Bo X, Yeh JS, Subang MC et al.(2011). Two cytokine signaling molecules co-operate to promote axonal transport and growth. Exp Neurol vol. 228, (2) 165-172.

Luo JA, Bo XN, Wu DS, Yeh J, Richardson PM, Zhang Y(2011). Promoting Survival, Migration, and Integration of Transplanted Schwann Cells by Over-Expressing Polysialic Acid. GLIA vol. 59, (3) 424-434.

Luo J, Bo X, Wu D, Yeh J, Richardson PM, Zhang Y(2011). Promoting Survival, Migration, and Integration of Transplanted Schwann Cells by Over-expressing Polysialic Acid. Glia

Luo J, Bo X, Wu D, Yeh J, Richardson PM, Zhang Y(2010). Promoting survival, migration, and integration of transplanted Schwann cells by over-expressing polysialic acid. Glia

Wu DS, Yang P, Zhang XY, Luo J, Haque ME, Yeh J, Richardson PM, Zhang Y et al.(2009). Targeting a Dominant Negative Rho Kinase to Neurons Promotes Axonal Outgrowth and Partial Functional Recovery After Rat Rubrospinal Tract Lesion. MOL THER vol. 17, (12) 2020-2030.

Richardson PM, Miao TZ, Wu DS, Zhang Y, Yeh J, Bo XN(2009). RESPONSES OF THE NERVE CELL BODY TO AXOTOMY. NEUROSURGERY vol. 65, (4) A74-A79.

Richardson PM, Miao T, Wu D, Zhang Y, Yeh J, Bo X(2009). Responses of the Nerve Cell Body to Axotomy. Neurosurgery vol. 65, (suppl_4) A74-A79.

Zhang Y, Yeh J, Richardson PM, Bo X(2008). Cell adhesion molecules of the immunoglobulin superfamily in axonal regeneration and neural repair. Restorative Neurology and Neuroscience vol. 26, (2-3 AXONAL REGENERATO) 81-96.

Miao TZ, Wu DS, Zhang Y, Bo XN, Xiao F, Zhang XY, Magoulas C, Subang MC et al.(2008). SOCS3 suppresses AP-1 transcriptional activity in neuroblastoma cells through inhibition of c-Jun N-terminal kinase. MOL CELL NEUROSCI vol. 37, (2) 367-375.

Zhang Y, Yeh J, Richardson PM, Bo XN(2008). Cell adhesion molecules of the immunoglobulin superfamily in axonal regeneration and neural repair. RESTOR NEUROL NEUROS vol. 26, (2-3) 81-96.

Zhang Y, Zhang XY, Wu DS, Verhaagen J, Richardson PM, Yeh J, Bo XN(2007). Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory Axons into spinal cord. MOL THER vol. 15, (10) 1796-1804.

Zhang Y, Ghadiri-Sani M, Zhang XY, Richardson PM, Yeh J, Bo XN(2007). Induced expression of polysialic acid in the spinal cord promotes regeneration of sensory axons. MOL CELL NEUROSCI vol. 35, (1) 109-119.

Wu DS, Zhang Y, Bo XN, Huang WL, Xiao F, Zhang XY, Miao TZ, Magoulas C et al.(2007). Actions of neuropoietic cytokines and cyclic AMP in regenerative conditioning of rat primary sensory neurons. EXP NEUROL vol. 204, (1) 66-76.

Zhang Y, Zhang X, Yeh J, Richardson P, Bo X(2007). Engineered expression of polysialic acid enhances Purkinje cell axonal regeneration in L1/GAP-43 double transgenic mice. Eur J Neurosci vol. 25, (2) 351-361.

Miao T, Wu DS, Zhang Y, Bo XN, Subang MC, Wang P, Richardson PM(2006). Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons. J NEUROSCI vol. 26, (37) 9512-9519.

Zhang XY, Bo XN, Anderson PN, Lieberman AR, Zhang Y(2006). Distribution and expression of tissue inhibitors of metalloproteinase in dorsal root entry zone and dorsal column after dorsal root injury. J NEUROSCI RES vol. 84, (2) 278-290.

Zhang Y, Bo XN, Schoepfer R, Holtmaat AJDG, Verhaagen J, Emson PC, Lieberman AR, Anderson PN(2005). Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo. P NATL ACAD SCI USA vol. 102, (41) 14883-14888.

Zhang Y, Bo X, Schoepfer R, Holtmaat AJDG, Verhaagen J, Emson PC, Lieberman AR, Anderson PN(2005). Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo. Proc Natl Acad Sci U S A vol. 102, (41) 14883-14888.

Jiang LH, Kim M, Spelta V, Bo XN, Surprenant A, North RA(2003). Subunit arrangement in P2X receptors. J NEUROSCI vol. 23, (26) 8903-8910.

Bo XN, Jiang LH, Wilson HL, Kim M, Burnstock G, Surprenant A, North RA(2003). Pharmacological and biophysical properties of the human P2X(5) receptor. MOL PHARMACOL vol. 63, (6) 1407-1416.

Bo XN, Kim M, Nori SL, Schoepfer R, Burnstock G, North RA(2003). Tissue distribution of P2X(4) receptors studied with an ectodomain antibody. CELL TISSUE RES vol. 313, (2) 159-165.

BO X, Liu M, Burnstock G, Schoepfer R(2001). Characterization and expression of ATP P2X(4) receptor from embryonic chick skeletal muscle. Drug Develop Res. vol. 53, 22-28.

Bo X, Burnstock G(2001). Localization of ATP P2X Receptors. Ion Channel Localization Methods and Protocols, Editors: Lopatin, A, Nichols, C, The Humana Press Inc (Totowa),

Bo XN, Schoepfer R, Burnstock G(2000). Molecular cloning and characterization of a novel ATP P2X receptor subtype from embryonic chick skeletal muscle. J BIOL CHEM vol. 275, (19) 14401-14407.

Bo X, Alavi A, Xiang Z, Oglesby I, Ford A, Burnstock G(1999). Localization of ATP-gated P2X2 and P2X3 receptor immunoreactive nerves in rat taste buds. NeuroReport vol. 10, (5) 1107-1111.

Xiang Z, Bo X, Burnstock G(1999). P2X receptor immunoreactivity in the rat cochlea, vestibular ganglion and cochlear nucleus. vol. 128, (1-2) 190-196.

Nori S, Fumagalli L, Bo X, Bogdanov Y, Burnstock G(1998). Coexpression of mRNAs for P2X1, P2X2 and P2X4 receptors in rat vascular smooth muscle: an in situ hybridization and RT-PCR study. J Vasc Res vol. 35, (3) 179-185.

Xiang Z, Bo X, Burnstock G(1998). Localization of ATP-gated P2X receptor immunoreactivity in rat sensory and sympathetic ganglia. Neuroscience Letters vol. 256, (2) 105-108.

Xiang Z, Bo X, Oglesby I, Ford A, Burnstock G(1998). Localization of ATP-gated P2X2 receptor immunoreactivity in the rat hypothalamus. Brain Research vol. 813, (2) 390-397.

Bo X, Karoon P, Nori SL, Bardini M, Burnstock G(1998). P2X purinoceptors in postmortem human cerebral arteries. Journal of Cardiovascular Pharmacology vol. 31, (5) 794-799.

Bo X, Sexton A, Xiang Z, Nori SL, Burnstock G(1998). Pharmacological and histochemical evidence for P2X receptors in human umbilical vessels. European Journal of Pharmacology vol. 353, (1) 59-65.

Zhong Y, Dunn PM, Xiang Z, Bo X, Burnstock G(1998). Pharmacological and molecular characterization of P2X receptors in rat pelvic ganglion neurons. British Journal of Pharmacology vol. 125, (4) 771-781.

Vallejo AI, Bo XN, Burnstock G(1996). P2Y purinoceptors in gastric gland plasma membranes. EUR J PHARMACOL vol. 312, (2) 209-214.

Lambrecht G, Ardanuy U, Bäumert HG, Bo X, Hoyle CHV, Nickel P, Pfaff O, Ralevic V et al.(1996). Design and pharmacological characterization of selective P2-purinoceptor antagonists. Perspectives in Receptor Research, Editors: Giardinà, D, Piergentili, A, Pigini, M, Elsevier (Amsterdam),

Zhao M, Bo X, Burnstock G(1996). Distribution of [3H] alpha, beta-methylene ATP binding sites in pulmonary blood vessels of different species. Pulm Pharmacol vol. 9, (3) 167-174.

Neely CF, Matot I, Batra VK, Bo XN, Burnstock G(1996). P-2X purinoceptors in the feline pulmonary vascular bed: Distribution and selective in vivo pharmacological probes. AM J PHYSIOL-LUNG C vol. 14, (6) L889-L897.

Zhao M, Bo XN, Neely CF, Burnstock G(1996). Characterization and autoradiographic localization of [H-3]alpha,beta-methylene ATP binding sites in cat urinary bladder. GEN PHARMACOL vol. 27, (3) 509-512.

BO XN, ZHANG Y, NASSAR M, BURNSTOCK G, SCHOEPFER R(1995). A P2X PURINOCEPTOR CDNA CONFERRING A NOVEL PHARMACOLOGICAL PROFILE. FEBS LETT vol. 375, (1-2) 129-133.

Bo X, Burnstock G(1995). Characterization and autoradiographic localization of [3H] alpha, beta-methylene adenosine 5'-triphosphate binding sites in human urinary bladder. Br J Urol vol. 76, (3) 297-302.

MOCKETT BG, BO XN, HOUSLEY GD, THORNE PR, BURNSTOCK G(1995). AUTORADIOGRAPHIC LABELING OF P-2 PURINOCEPTORS IN THE GUINEA-PIG COCHLEA. HEARING RES vol. 84, (1-2) 177-193.

BO XN, BURNSTOCK G(1994). DISTRIBUTION OF [H-3] ALPHA,BETA-METHYLENE ATP BINDING-SITES IN RAT-BRAIN AND SPINAL-CORD. NEUROREPORT vol. 5, (13) 1601-1604.

BO XN, FISCHER B, MAILLARD M, JACOBSON KA, BURNSTOCK G(1994). COMPARATIVE-STUDIES ON THE AFFINITIES OF ATP DERIVATIVES FOR P-2X-PURINOCEPTORS IN RAT URINARY-BLADDER. BRIT J PHARMACOL vol. 112, (4) 1151-1159.

ZIGANSHIN AU, HOYLE CHV, BO XN, LAMBRECHT G, MUTSCHLER E, BAUMERT HG, BURNSTOCK G(1993). PPADS SELECTIVELY ANTAGONIZES P(2X)-PURINOCEPTOR-MEDIATED RESPONSES IN THE RABBIT URINARY-BLADDER. BRIT J PHARMACOL vol. 110, (4) 1491-1495.

BO XN, BURNSTOCK G(1993). TRIPHOSPHATE, THE KEY STRUCTURE OF THE ATP MOLECULE RESPONSIBLE FOR INTERACTION WITH P(2X)-PURINOCEPTORS. GEN PHARMACOL vol. 24, (3) 637-640.

BO XN, BURNSTOCK G(1993). HETEROGENEOUS DISTRIBUTION OF [H-3] ALPHA,BETA-METHYLENE ATP BINDING-SITES IN BLOOD-VESSELS. J VASC RES vol. 30, (2) 87-101.

BO XN, SIMON J, BURNSTOCK G, BARNARD EA(1992). SOLUBILIZATION AND MOLECULAR-SIZE DETERMINATION OF THE P(2X) PURINOCEPTOR FROM RAT VAS-DEFERENS. J BIOL CHEM vol. 267, (25) 17581-17587.

BO XN, BURNSTOCK G(1992). SPECIES-DIFFERENCES IN CHARACTERISTICS AND DISTRIBUTION OF [H-3] ALPHA,BETA-METHYLENE ATP BINDING-SITES IN URINARY-BLADDER AND URETHRA OF RAT, GUINEA-PIG AND RABBIT. EUR J PHARMACOL vol. 216, (1) 59-66.

BO XN, NEELY CF, BURNSTOCK G(1992). AUTORADIOGRAPHIC LOCALIZATION OF P2-PURINOCEPTORS IN CAT AND HUMAN PULMONARY VESSELS WITH [H-3] ALPHA,BETA-MEATP. FASEB J vol. 6, (4) A1555-A1555.

Bo XN, Burnstock G(1990). High- and low-affinity binding sites for [3H]-alpha, beta-methylene ATP in rat urinary bladder membranes. Br J Pharmacol vol. 101, (2) 291-296.

Bo XN, Burnstock G(1990). The effects of Bay K 8644 and nifedipine on the responses of rat urinary bladder to electrical field stimulation, beta,gamma-methylene ATP and acetylcholine. Br J Pharmacol vol. 101, (2) 494-498.

Bo X, Burnstock G(1989). [3H]-alpha, beta-methylene ATP, a radioligand labelling P2-purinoceptors. Journal of Autonomic Nervous System vol. 28, (1) 85-88.