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Publications: Prof Michele Bombardieri

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Lendrem D, Mitchell S, McMeekin P, Gompels L, Hackett K, Bowman S, Price E, Pease CT et al. ( 2015 ) . Do the EULAR Sjögren's syndrome outcome measures correlate with health status in primary Sjögren's syndrome? . Rheumatology (Oxford) vol. 54 , ( 4 ) 655 - 659 .
Kelly S, Bombardieri M, Humby F, Ng N, Marrelli A, Riahi S, DiCicco M, Mahto A et al. ( 2015 ) . Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study . Arthritis Res Ther vol. 17 , ( 1 )
Kelly S, Bombardieri M, Humby F, Ng N, Marrelli A, Riahi S, DiCicco M, Mahto A et al. ( 2015 ) . Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early rheumatoid arthritis: an observational study . Arthritis Research & Therapy vol. 17 , ( 1 )
Kelly S, Humby F, Filer A, Ng N, Di Cicco M, Hands RE, Rocher V, Bombardieri M et al. ( 2015 ) . Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients . Ann Rheum Dis vol. 74 , ( 3 ) 611 - 617 .
Nayar S, Campos J, Cloake T, Bowman S, Bombardieri M, Pitzalis C, Luther S, Buckley C et al. ( 2015 ) . IL22 Regulates Autoantibody Production by Inducing Lymphoid Chemokine Expression in Tertiary Lymphoid Organs . SCANDINAVIAN JOURNAL OF IMMUNOLOGY . vol. 81 , 425 - 425 .
Murray-Brown W, Carlotti E, Floyd J, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Mehr R et al. ( 2015 ) . Next-Generation Sequencing Demonstrates Dynamic Recirculation of B Cell Clones in Ectopic Lymphoid Structures of Sjogren's Syndrome . SCANDINAVIAN JOURNAL OF IMMUNOLOGY . vol. 81 , 401 - 402 .
Astorri E, Croia C, Picarelli G, Sutcliffe N, Tappuni A, Bombardieri M, Priori R ( 2015 ) . Routine Investigations for Circulating IgG4 and/or IgG4+Salivary Gland Histopathology Fail to Reveal Undiagnosed Cases of IgG4 Related Disease in Sicca Patients not Fulfilling the Diagnosis of Sjogren's Syndrome . SCANDINAVIAN JOURNAL OF IMMUNOLOGY . vol. 81 , 341 - 341 .
Astorri E, Nerviani A, Bombardieri M, Pitzalis C ( 2015 ) . Towards a stratified targeted approach with biologic treatments in rheumatoid arthritis: role of synovial pathobiology . Current Pharmaceutical Design vol. 21 , ( 17 ) 2216 - 2224 .
Fisher B, Jonsson R, Daniels T, Bombardieri M, Morgan P, Brown R, Bowman S, Barone F ( 2015 ) . Towards the Standardisation of Salivary Gland Histopathology for Use in the Diagnosis of Primary Sjogren's Syndrome and in Clinical Trials. Report of a Preliminary Workshop . SCANDINAVIAN JOURNAL OF IMMUNOLOGY . vol. 81 , 333 - 334 .
VARTOUKIAN SR, Tilakaratne W, Seoudi N, Bombardieri M, Bergmeier L, Tappuni A, Fortune F ( 2014 ) . Dysregulation of the SOCS3-STAT3 pathway in the aetio-pathogenesis of Sjögren’s syndrome . Clinical and Experimental Immunology vol. 177 , ( 3 ) 618 - 629 .
Croia C, Astorri E, Murray-Brown W, Willis A, Brokstad KA, Sutcliffe N, Piper K, Jonsson R et al. ( 2014 ) . Implication of Epstein-Barr virus infection in disease-specific autoreactive B cell activation in ectopic lymphoid structures of Sjögren's syndrome . Arthritis Rheumatol vol. 66 , ( 9 ) 2545 - 2557 .
Pitzalis C, Jones GW, Bombardieri M, Jones SA ( 2014 ) . Ectopic lymphoid-like structures in infection, cancer and autoimmunity . Nat Rev Immunol vol. 14 , ( 7 ) 447 - 462 .
Ng N, Kelly S, Humby F, DiCicco M, Rocher V, Hands R, Bombardieri M, Pitzalis C ( 2014 ) . OP0054 Ultrasound Synovitis Reflects Synovial Inflammation at A Histopathological Level . Annals of the Rheumatic Diseases . vol. 73 ,
Corsiero E, Carlotti E, Pratesi F, Wardemann H, Robinson W, Migliorini P, Pitzalis C, Bombardieri M ( 2014 ) . OP0266 Monoclonal Antibodies Derived from Single CD19+ Synovial B Cells of RA Patients with Tertiary Lymphoid Structures Display Preferential Immunoreactivity towards Citrullinated Proteins of Nets . Annals of the Rheumatic Diseases . vol. 73 ,
Di Cicco M, Kelly S, Humby F, Ng N, Nerviani A, Rocher V, Hands R, Bombardieri M et al. ( 2014 ) . SAT0048 Synovial Lymphocytic Aggregates Predict Clinical Response to Certolizumab Pegol in Rheumatoid Arthritis (Clinical and Pathological Response to Certolizumab-Pegol (Clip-Cert) Study) . Annals of the Rheumatic Diseases . vol. 73 ,
Lucchesi D, Pitzalis C, Bombardieri M ( 2014 ) . EBV and other viruses as triggers of tertiary lymphoid structures in primary Sjögren's syndrome . Expert Rev Clin Immunol vol. 10 , ( 4 ) 445 - 455 .
Corsiero E, Carlotti E, Wardemann H, Robinson W, Migliorini P, Pratesi F, Pitzalis C, Bombardieri M ( 2014 ) . A1.31 Monoclonal antibodies from CD19+ synovial B cells of RA patients with tertiary lymphoid structures display a strong immunoreactivity towards citrullinated histones from neutrophils NETs . Annals of the Rheumatic Diseases . vol. 73 ,
Corsiero E, Bombardieri M, Carlotti E, Pratesi F, Robinson W, Migliorini P, Pitzalis C ( 2014 ) . Citrullinated histones from neutrophil extracellular traps (NETs) fuel ectopic germinal centre responses and ACPA production in rheumatoid joints . IMMUNOLOGY vol. 143 , 43 - 43 .
Pontarini E, Lucchesi D, Bombardieri M, Mavilio D ( 2014 ) . Recruitment and activation of NK cells regulates early immune responses to viral infection in the salivary glands of an inducible murine model of Sjogren-like disease . IMMUNOLOGY vol. 143 , 93 - 93 .
Brown S, Coy NN, Pitzalis C, Emery P, Pavitt S, Gray J, Hulme C, Hall F et al. ( 2014 ) . The TRACTISS Protocol: a randomised double blind placebo controlled clinical TRial of Anti-B-Cell Therapy In patients with primary Sjogren's Syndrome . BMC MUSCULOSKELETAL DISORDERS vol. 15 , Article ARTN 21 ,
Croia C, Serafini B, Bombardieri M, Kelly S, Humby F, Severa M, Rizzo F, Coccia EM et al. ( 2013 ) . Epstein-Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis . Ann Rheum Dis vol. 72 , ( 9 ) 1559 - 1568 .
Strollo R, Ponchel F, Malmström V, Rizzo P, Bombardieri M, Wenham CY, Landy R, Perret D et al. ( 2013 ) . Autoantibodies to posttranslationally modified type II collagen as potential biomarkers for rheumatoid arthritis . Arthritis Rheum vol. 65 , ( 7 ) 1702 - 1712 .
Lendrem D, Mitchell S, McMeekin P, Bowman S, Price E, Pease CT, Emery P, Andrews J et al. ( 2013 ) . Health-related utility values of patients with primary Sjögren's syndrome and its predictors . Annals of the Rheumatic Diseases
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M ( 2013 ) . ACCUMULATION OF CIRCULATING AUTOREACTIVE NAIVE B CELLS REVEALS DEFECTS OF EARLY B-CELL TOLERANCE CHECKPOINTS IN PATIENTS WITH SJOGREN'S SYNDROME . RHEUMATOLOGY . vol. 52 , 159 - 159 .
Ng N, Humby F, Bombardieri M, Kelly S, Di Cicco M, Dadoun S, Hands R, Rocher V et al. ( 2013 ) . CLINICAL, IMAGING AND HISTOLOGICAL CHARACTERISTICS OF PATIENTS WITH RHEUMATOID ARTHRITIS AT DIFFERENT STAGES OF DISEASE PROGRESSION . RHEUMATOLOGY . vol. 52 , 71 - 71 .
Kam NW, Filter A, Buckley C, Pitzalis C, Bombardieri M ( 2013 ) . MEMBRANE-BOUND AND SOLUBLE BAFF EXPRESSION BY HUMAN RHEUMATOID FIBROBLAST-LIKE SYNOVIOCYTES IN RESPONSE TO TLR STIMULATION . RHEUMATOLOGY . vol. 52 , 80 - 80 .
Di Cicco M, Humby F, Kelly S, Ng N, Hands R, Dadoun S, Buckley C, McInnes IB et al. ( 2013 ) . SYNOVIAL LYMPHOCYTE AGGREGATES IN EARLY INFLAMMATORY ARTHRITIS: CORRELATION WITH DIAGNOSIS, DISEASE ACTIVITY AND ANTIBODY STATUS . RHEUMATOLOGY . vol. 52 , 29 - 29 .
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M ( 2013 ) . ACCUMULATION OF CIRCULATING AUTOREACTIVE NAIVE B CELLS REVEAL DEFECTS OF EARLY B CELL TOLERANCE CHECKPOINTS IN PATIENTS WITH SJOGREN'S SYNDROME . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 792 - 792 .
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M ( 2013 ) . Accumulation of Circulating Autoreactive Naive B Cells Reveal Defects of Early B Cell Tolerance Checkpoints in Patients with Sjogren's Syndrome . ANNALS OF THE RHEUMATIC DISEASES . vol. 72 , A30 - A31 .
Patel HB, Bombardieri M, Pitzalis C, Perretti M ( 2013 ) . Activation of Melanocortin Receptor 3 as a new strategy to control experimental and rheumatoid arthritis . FASEB JOURNAL . vol. 27 ,
Croia C, Serafini B, Tappuni A, Aloisi F, Sutcliffe N, Pitzalis C, Bombardieri M ( 2013 ) . ECTOPIC LYMPHOID STRUCTURES SUPPORT EPSTEIN-BARR VIRUS PERSISTENCE AND AUTOREACTIVE PLASMA CELL INFECTION IN SJOGREN'S SYNDROME SALIVARY GLANDS . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 462 - 462 .
Ng W-F, Lendrem D, Mitchell S, Bowman S, Price E, Pease C, Emery P, Andrews J et al. ( 2013 ) . EVALUATING HEALTH STATUS OF 620 PATIENTS WITH PRIMARY SJOGREN'S SYNDROME USING EQ-5D . ANNALS OF THE RHEUMATIC DISEASES vol. 71 , 466 - 466 .
Astorri E, Scrivo R, Bombardieri M, Picarelli G, Pecorella I, Porzia A, Valesini G, Priori R ( 2013 ) . EXPRESSION OF FRACTALKINE IN SJOGREN'S SYNDROME PATIENTS: CELLULAR AND MOLECULAR CHARACTERIZATION OF CX3CL1 AND CX3CR1 IN SERA AND SALIVARY GLANDS . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 78 - 78 .
Ng W-F, Mitchell S, Lendrem D, Bowman S, Price E, Pease C, Emery P, Andrews J et al. ( 2013 ) . HOW GOOD ARE THE EULAR SJOGREN'S SYNDROME DISEASE ACTIVITY INDEX (ESSDAI), AND EULAR SJOGREN'S SYNDROME PATIENTS REPORTED INDEX (ESSPRI) IN PREDICTING HEALTH STATUS IN PRIMARY SJOGREN'S SYNDROME? . ANNALS OF THE RHEUMATIC DISEASES vol. 71 , 553 - 554 .
Lucchesi D, Bombardieri M, Barone F, Nayar S, Proctor G, Buckley CD, Pitzalis C ( 2013 ) . INDUCIBLE TERTIARY LYMPHOID STRUCTURES AND AUTOIMMUNITY IN A NOVEL MODEL OF SIALOADENITIS IN WILD-TYPE MICE . ANNALS OF THE RHEUMATIC DISEASES . vol. 72 , A42 - A42 .
Jones GW, Bombardieri M, Greenhill CJ, McLeod L, Rocher V, Williams AS, Pitzalis C, Jenkins BJ et al. ( 2013 ) . Interleukin-27 as a novel antagonist of ectopic lymphoid-like structure development in early inflammatory arthritis . CYTOKINE . vol. 63 , 274 - 274 .
Murray-Brown W, Croia C, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Pitzalis C, Bombardieri M ( 2013 ) . LESIONAL IL-21 EXPRESSION CORRELATES WITH FUNCTIONAL GERMINAL CENTER FORMATION AND T FOLLICULAR HELPER CELL INFILTRATION IN THE SALIVARY GLANDS OF SJOGREN'S SYNDROME . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 77 - 77 .
Ng W-F, Miller A, Bowman S, Price E, Kitas G, Pease C, Emery P, Lanyon P et al. ( 2013 ) . LEVEL OF PHYSICAL ACTIVITY IN PRIMARY SJOGREN'S SYNDROME AND ITS PREDICTORS . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 483 - 484 .
Murray-Brown W, Croia C, Sutcliffe N, Tappuni A, Pitzalis C, Bombardieri M ( 2013 ) . Lesional Intereukin-21 Expression Correlates With Functional Germinal Center Formation and T Follicular Helper Cell Infiltration In The Salivary Glands Of Sjogren's Syndrome . ARTHRITIS AND RHEUMATISM . vol. 65 , S634 - S634 .
Bombardieri M, Rocher V, Mittereder N, Carlesso G, Herbst R, Sleeman M, Pitzalis C ( 2013 ) . MAVRILIMUMAB REDUCES PRO-INFLAMMATORY CYTOKINES AND CD68 POSITIVE MACROPHAGES IN SYNOVIAL EXPLANTS FROM RHEUMATOID ARTHRITIS SUBJECTS ENGRAFTED INTO SCID/BEIGE MICE . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 156 - 157 .
Ng N, Humby F, Kelly S, Di Cicco M, Dadoun S, Bombardieri M, Hands R, Rocher V et al. ( 2013 ) . RHEUMATOID ARTHRITIS PATIENT CHARACTERISTICS AT DIFFERENT THERAPEUTIC TIMEPOINTS . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 862 - 862 .
Corsiero E, Bombardieri M, Carlotti E, Wardemann H, Robinson WH, Pitzalis C ( 2013 ) . Recombinant Monoclonal Antibodies Derived From Single CD19+Synovial B Cells Of RA Patients With Tertiary Lymphoid Structures Display a Strong Immunoreactivity Towards Citrullinated Histones . ARTHRITIS AND RHEUMATISM . vol. 65 , S1127 - S1128 .
Tarn J, Mitchell S, Bowman S, Price E, Pease C, Sutcliffe N, Emery P, Andrews J et al. ( 2013 ) . SERUM CYTOKINE AND CHEMOKINE PROFILING IN PRIMARY SJOGREN'S SYNDROME . ANNALS OF THE RHEUMATIC DISEASES vol. 71 , 527 - 528 .
Di Cicco M, Dadoun S, Humby F, Kelly S, Ng N, Hands RE, Buckley C, McInnes I et al. ( 2013 ) . SYNOVIAL ECTOPIC LYMPHOID-LIKE STRUCTURES ARE ASSOCIATED WITH DIAGNOSIS OF RHEUMATOID ARTHRITIS, DISEASE ACTIVITY AND ANTIBODY STATUS IN EARLY ARTHRITIS PATIENTS . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 192 - 192 .
Croia C, Serafini B, Bombardieri M, Kelly S, Humby F, Severa M, Rizzo F, Coccia EM et al. ( 2013 ) . SYNOVIAL LYMPHOID STRUCTURES SUPPORT EPSTEIN-BARR VIRUS PERSISTENCE AND AUTOREACTIVE PLASMA CELL INFECTION IN RHEUMATOID ARTHRITIS . ANNALS OF THE RHEUMATIC DISEASES . vol. 72 , A43 - A44 .
Deidda S, Humby F, Kelly S, Di Cicco M, Ng N, Hands R, Bombardieri M, Pitzalis C ( 2013 ) . SYNOVIAL SUBLINING MACROPHAGES: A SENSITIVE BIOMARKER FOR RESPONSE TO TREATMENT IN EARLY RA PATIENTS . ANNALS OF THE RHEUMATIC DISEASES vol. 72 , 583 - 584 .
Kam YNW, Filer A, Buckley CD, Pitzalis C, Bombardieri M ( 2013 ) . Secretory Leukocyte Protease Inhibitor Released By Rheumatoid Synovial Fibroblasts Exerts a Negative Control Of BAFF-Dependent B Cell Activation In Vitro and In Vivo In The Collagen-Induced and Chimeric RA/SCID Arthritis Models . ARTHRITIS AND RHEUMATISM . vol. 65 , S1029 - S1029 .
Di Cicco M, Kelly S, Humby F, Ng N, Dadoun S, Hands R, Rocher V, Nerviani A et al. ( 2013 ) . Synovial Ectopic Lymphoneogenesis Predicts Clinical Response To Certolizumab Pegol In Patients With Rheumatoid Arthritis . ARTHRITIS AND RHEUMATISM . vol. 65 , S556 - S556 .
Ciccia F, Rizzo A, Accardo-Palumbo A, Giardina A, Bombardieri M, Guggino G, Taverna S, Leo GD et al. ( 2012 ) . Increased expression of interleukin-32 in the inflamed ileum of ankylosing spondylitis patients . Rheumatology (Oxford) vol. 51 , ( 11 ) 1966 - 1972 .
Bombardieri M, Barone F, Lucchesi D, Nayar S, van den Berg WB, Proctor G, Buckley CD, Pitzalis C ( 2012 ) . Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice . J Immunol vol. 189 , ( 7 ) 3767 - 3776 .
Croia C, Bombardieri M, Francesca A, Serafini B, Humby F, Kelly S, Migliorini P, Pitzalis C ( 2012 ) . ANTI-VCA AND EBNA1 ANTIBODIES ARE PRODUCED IN THE RHEUMATOID SYNOVIUM IN THE PRESENCE OF ECTOPIC LYMPHOID STRUCTURES AND CORRELATE WITH ACPA PRODUCTION . RHEUMATOLOGY . vol. 51 , 43 - 43 .
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M ( 2012 ) . Accumulation of circulating autoreactive naive B cells reveal defects of early B cell tolerance checkpoints in patients with Sjogren's syndrome . IMMUNOLOGY . vol. 137 , 327 - 327 .
Newton JL, Frith J, Powell D, Hackett K, Wilton K, Bowman S, Price E, Pease C et al. ( 2012 ) . Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjogren's syndrome . ANNALS OF THE RHEUMATIC DISEASES vol. 71 , ( 12 ) 1973 - 1979 .
Nayar S, Cloake T, Bombardieri M, Pitzalis C, Buckley C, Barone F ( 2012 ) . ECTOPIC LYMPHONEOGENESIS IN A NOVEL MURINE MODEL OF SALIVARY GLANDS SIALOADENITIS IS CHARACTERIZED BY ASYNCHRONY IN THE LYMPHANGIOGENETIC AND ANGIOGENETIC PROGRAM . RHEUMATOLOGY . vol. 51 , 143 - 144 .
Lendrem D, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M et al. ( 2012 ) . EVALUATING HEALTH STATUS OF 620 PATIENTS WITH PRIMARY SJOGREN'S SYNDROME USING EQ-5D . RHEUMATOLOGY . vol. 51 , 171 - 171 .
Lendrem D, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M et al. ( 2012 ) . HOW GOOD ARE THE EULAR SJOGREN'S SYNDROME DISEASE ACTIVITY INDEX, AND EULAR SJOGREN'S SYNDROME PATIENTS REPORTED INDEX IN PREDICTING HEALTH STATUS IN PRIMARY SJOGREN'S SYNDROME? . RHEUMATOLOGY . vol. 51 , 176 - 176 .
Jones GW, Greenhill CJ, Williams AS, Nowell MA, Bombardieri M, Pitzalis C, Jenkins BJ, Jones SA ( 2012 ) . IL-27 control of ectopic lymphoid structures in inflammatory arthritis . IMMUNOLOGY . vol. 137 , 44 - 44 .
Lucchesi D, Bombardieri M, Barone F, Nayar S, Proctor G, Buckley CD, Pitzalis C ( 2012 ) . Inducible tertiary lymphoid structures formation in a novel model of sialoadenitis in wild-type mice is preceded by ectopic expression of lymphoid chemokines . IMMUNOLOGY . vol. 137 , 189 - 189 .
Murray-Brown W, Croia C, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Pitzalis C, Bombardieri M ( 2012 ) . Lesional IL-21 expression correlates with functional germinal center formation and T follicular helper cell infiltration in the salivary glands of Sjogren's syndrome . IMMUNOLOGY . vol. 137 , 491 - 491 .
Murray-Brown W, Priori R, Tappuni T, Vartoukian S, Seoudi N, Picarelli G, Fortune F, Valesini G et al. ( 2012 ) . MONOCYTE-DERIVED IL-32 EXPRESSION CORRELATES WITH THE LEVEL OF INFLAMMATION IN SALIVARY GLANDS OF SJOGREN'S SYNDROME . RHEUMATOLOGY . vol. 51 , 176 - 176 .
Kam NW, Filer A, Buckley C, Bombardieri M, Pitzalis C ( 2012 ) . Membrane-bound and soluble BAFF expression by human rheumatoid fibroblast-like synoviocytes in response to TLR stimulation . IMMUNOLOGY . vol. 137 , 583 - 584 .
Vila J, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M et al. ( 2012 ) . THE CLINICAL RELEVANCE OF ANTI-RO52 AND ANTI-RO60 IN PATIENTS IN THE UNITED KINGDOM PRIMARY SJOGREN'S SYNDROME REGISTRY (UKPSSR) . RHEUMATOLOGY . vol. 51 , 35 - 35 .
DiCicco M, Humby F, Kelly S, Hands R, Buckley C, McInnes I, Taylor P, Bombardieri M et al. ( 2012 ) . THE PATHOBIOLOGY OF EARLY ARTHRITIS COHORT: A PRELIMINARY ANALYSIS CORRELATING HISTOMORPHOLOGY AND DISEASE ACTIVITY . RHEUMATOLOGY . vol. 51 , 149 - 149 .
Marrelli A, Bombardieri M, Kelly S, Cipriani P, Giacomelli R, Pitzalis C ( 2011 ) . DIGITAL IMAGE ANALYSIS FOR THE EVALUATION OF BLOOD VESSEL DENSITY IN RHEUMATOID SYNOVIUM: CORRELATION WITH QUANTITATIVE REAL-TIME PCR EXPRESSION OF ENDOTHELIAL ANTIGEN AND ANGIOGENIC GROWTH FACTORS . RHEUMATOLOGY . vol. 50 , 75 - 75 .
Croia C, Serafini B, Bombardieri M, Kelly S, Coccia EM, Severa M, Francesca A, Pitzalis C ( 2011 ) . EBV INFECTION IN THE RHEUMATOID ARTHRITIS SYNOVIUM: RELATIONSHIP TO ECTOPIC LYMPHOID STRUCTURES AND CD8 T CELL ACTIVATION . RHEUMATOLOGY . vol. 50 , 75 - 75 .
Bombardieri M ( 2011 ) . HOW WILL B-CELL BASIC SCIENCE RESEARCH DRIVE TREATMENT IN SJOGREN'S SYNDROME? . RHEUMATOLOGY . vol. 50 , 12 - 13 .
Astorri E, Bombardieri M, Gabba S, Peakman M, Pozzilli P, Pitzalis C ( 2011 ) . EVOLUTION OF ECTOPIC LYMPHOID NEOGENESIS AND IN SITU AUTOANTIBODIES PRODUCTION IN AUTOIMMUNE DIABETIC NOD MICE: CELLULAR AND MOLECULAR CHARACTERISATION OF TERTIARY LYMPHOID STRUCTURES IN PANCREATIC ISLETS . ANNALS OF THE RHEUMATIC DISEASES . vol. 70 ,
Bombardieri M, Kam YNW, Filer A, Buckley CD, Pitzalis C ( 2011 ) . Aberrant Basal and TLR-Stimulated Expression of TSLP in Rheumatoid Synovial Fibroblasts . ARTHRITIS AND RHEUMATISM . vol. 63 , S140 - S140 .
Kam NW, Bombardieri M, Filer A, Buckley C, Pitzalis C ( 2011 ) . Aberrant basal and TLR-stimulated expression of TSLP in rheumatoid synovial fibroblasts . IMMUNOLOGY . vol. 135 , 125 - 125 .
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M ( 2011 ) . Analysis of recombinant monoclonal antibodies from single B cells reveals early defects of B cell tolerance checkpoints in patients with Sjogren's syndrome . IMMUNOLOGY . vol. 135 , 72 - 72 .
Croia C, Bombardieri M, Serafini B, Coccia EM, Severa M, Kelly S, Aloisi F, Pitzalis C ( 2011 ) . EBV Infection In the Rheumatoid Synovium: Relationship with Ectopic Lymphoid Structures, In Situ Autoantobody Production and CD8 T Cell Activation . ARTHRITIS AND RHEUMATISM . vol. 63 , S140 - S140 .
Nayar S, Barone F, Choy P, Chang M-M, Bombardieri M, Lucchesi D, Pitzalis C, Buckley C ( 2011 ) . Ectopic lymphoneogenesis in a novel murine model of salivary glands sialoadenitis is characterized by asynchrony in the lymphangiogenetic and angiogenetic program . IMMUNOLOGY . vol. 135 , 49 - 49 .
Bombardieri M, Lucchesi D, Barone F, Nayar S, Proctor G, Buckley CD, Pitzalis C ( 2011 ) . Inducible functional tertiary lymphoid structures, autoimmunity and exocrine dysfunction in wild-type mouse salivary glands via local adenoviral delivery . IMMUNOLOGY . vol. 135 , 167 - 167 .
Bugatti S, Manzo A, Bombardieri M, Vitolo B, Humby F, Kelly S, Montecucco C, Pitzalis C ( 2011 ) . Synovial Tissue Heterogeneity and Peripheral Blood Biomarkers . CURRENT RHEUMATOLOGY REPORTS vol. 13 , ( 5 ) 440 - 448 .
Patel HB, Bombardieri M, Sampaio ALF, D'Acquisto F, Gray M, Grieco P, Getting SJ, Pitzalis C et al. ( 2010 ) . Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis . FASEB J vol. 24 , ( 12 ) 4835 - 4843 .
Corsiero E, Bombardieri M, Humby F, Manzo A, Kelly S, Pitzalis C ( 2010 ) . Characterization of inter follicular large B cells, a new subpopulation of B lymphocytes, in tertiary lymphoid organs in rheumatic autoimmune diseases . IMMUNOLOGY . vol. 131 , 33 - 33 .
Astorri E, Guglielmi C, Bombardieri M, Alessandri C, Buzzetti R, Maggi D, Valesini G, Pitzalis C et al. ( 2010 ) . Circulating Reg1α proteins and autoantibodies to Reg1α proteins as biomarkers of β-cell regeneration and damage in type 1 diabetes . Horm Metab Res vol. 42 , ( 13 ) 955 - 960 .
Croia C, Serafini B, Bombardieri M, Kelly S, Coccia EM, Severa M, Aloisi F, Pitzalis C ( 2010 ) . EBV infection in the rheumatoid arthritis synovium: relationship to tertiary lymphoid structures and CD8 T cell activation . IMMUNOLOGY . vol. 131 , 124 - 124 .
Astorri E, Bombardieri M, Gabba S, Peakman M, Pozzilli P, Pitzalis C ( 2010 ) . Evolution of ectopic lymphoid neogenesis and in-situ autoantibodies production in autoimmune diabetic NOD mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islet . IMMUNOLOGY . vol. 131 , 63 - 63 .
Ciccia F, Accardo-Palumbo A, Giardina A, Di Maggio P, Principato A, Bombardieri M, Rizzo A, Alessandro R et al. ( 2010 ) . Expansion of Intestinal CD4+CD25(high) Treg Cells in Patients With Ankylosing Spondylitis A Putative Role for Interleukin-10 in Preventing Intestinal Th17 Response . ARTHRITIS RHEUM-US vol. 62 , ( 12 ) 3625 - 3634 .
Lucchesi D, Astorri E, Bombardieri M, Corsiero E, Barone F, Proctor G, Pitzalis C ( 2010 ) . Molecular and cellular evolution of functional tertiary lymphoid structures in salivary glands of NOD mice . IMMUNOLOGY . vol. 131 , 59 - 59 .
Kam NW, Bombardieri M, Brentano F, Choi K, Kyburz D, Gay S, Mclnnes IB, Pitzalis C ( 2010 ) . Rheumatoid synovial fibroblasts support AID expression and Ig class-switching in B cells via a Baff-dependent TLR3-stimulated pathway . IMMUNOLOGY . vol. 131 , 71 - 71 .
Ciccia F, Bombardieri M, Rizzo A, Principato A, Giardina AR, Raiata F, Peralta S, Ferrante A et al. ( 2010 ) . Over-expression of paneth cell-derived anti-microbial peptides in the gut of patients with ankylosing spondylitis and subclinical intestinal inflammation . Rheumatology (Oxford) vol. 49 , ( 11 ) 2076 - 2083 .
Astorri E, Bombardieri M, Gabba S, Peakman M, Pozzilli P, Pitzalis C ( 2010 ) . Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets . J Immunol vol. 185 , ( 6 ) 3359 - 3368 .
Astorri E, Bombardieri M, Corsiero E, Gabba S, Barone F, Proctor G, Pitzalis C ( 2010 ) . MOLECULAR AND CELLULAR EVOLUTION OF FUNCTIONAL TERTIARY LYMPHOID STRUCTURES IN SALIVARY GLANDS OF NOD MICE . RHEUMATOLOGY . vol. 49 , I28 - I28 .
Bombardieri M, Kam YNW, Brentano F, Choi K, Kyburz D, Gay S, McInnes IB, Pitzalis C ( 2010 ) . RHEUMATOID SYNOVIAL FIBROBLASTS SUPPORT AID EXPRESSION AND IG CLASS-SWITCHING IN B CELLS VIA A BAFF-DEPENDENT TLR3-STIMULATED PATHWAY . RHEUMATOLOGY . vol. 49 , I26 - I27 .
Swales C, Mahoney DJ, Athanasou NA, Bombardieri M, Pitzalis C, Sharif O, Day AJ, Milner CM et al. ( 2010 ) . TSG-6: AN AUTOCRINE REGULATOR OF INFLAMMATORY JOINT DISEASE? . RHEUMATOLOGY . vol. 49 , I27 - I27 .
Bombardieri M, Astorri E, Corsiero E, Gabba S, Barone F, Proctor G, Pitzalis C ( 2010 ) . MOLECULAR AND CELLULAR EVOLUTION OF FUNCTIONAL TERTIARY LYMPHOID STRUCTURES IN SALIVARY GLANDS OF NOD MICE . ANNALS OF THE RHEUMATIC DISEASES . vol. 69 ,
Manzo A, Bombardieri M, Humby F, Pitzalis C ( 2010 ) . Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling . IMMUNOL REV vol. 233 , 267 - 285 .
Patel HB, Bombardieri M, Pitzalis C, Perretti M ( 2009 ) . Activation of melanocortin receptor type 3 as a new strategy to control experimental and rheumatoid arthritis . EUR J CLIN INVEST vol. 39 , 29 - 29 .
Bombardieri M, Ciccia F, Principato A, Tripodo C, Peralta S, Triolo G, Pitzalis C ( 2009 ) . IL-23 OVEREXPRESSION AS IMMUNOLOGICAL SIGNATURE OF SUBCLINICAL INTESTINAL INFLAMMATION IN ANKYLOSING SPONDYLITIS . RHEUMATOLOGY . vol. 48 , I6 - I6 .
Humby F, Bombardieri M, Manzo A, Kelly S, Blades MC, Kirkham B, Spencer J, Pitzalis C ( 2009 ) . Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium . PLoS Med vol. 6 , ( 1 )
Guglielmi C, Astorri E, Portuesi R, Bombardieri M, Valorani M, Pozzilli P ( 2008 ) . A diet rich in protein and poor in starch with reduced food intake prevents diabetes in the NOD moose: the significance of Reg gene expression in the pancreas . DIABETOLOGIA vol. 51 , S229 - S229 .
Humby F, Bombardieri M, Antonio M, Blades M, Bruce K, Spencer J, Pitzalis C ( 2008 ) . Ectopic lymphoid structures expressing AID drive self sustained in situ prodction of autoantibodies in rheumatoid synovium . ARTHRITIS AND RHEUMATISM . vol. 58 , S633 - S634 .
Bombardieri M, Barone F, Humby F, Morgan P, Challacombe S, Spencer J, Pitzalis C ( 2008 ) . Activation-induced cytidine deaminase expression supports functionality of ectopic lymphoid neogenesis in patients with and animal models of Sjogren's syndrome . RHEUMATOLOGY . vol. 47 , II85 - II85 .
Humby F, Bombardieri M, Manzo A, Blades M, Kirkham B, Spencer J, Pitzalis C ( 2008 ) . Activation-induced cytidine deaminase supports self sustained autoantibody production within RA synovium . RHEUMATOLOGY . vol. 47 , II59 - II59 .
Astorri E, Bombardieri M, Guglielmi C, Pitzalis C, Pozzilli P ( 2008 ) . Beta cell regeneration in type 1 diabetes: the role of Reg genes in NOD mice . DIABETOLOGIA vol. 51 , S186 - S186 .
Bombardieri M, Barone F, Humby F, Kelly S, McGurk M, Morgan P, Challacombe S, De Vita S et al. ( 2007 ) . Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome . J Immunol vol. 179 , ( 7 ) 4929 - 4938 .
Bombardieri M, McInnes IB, Pitzalis C ( 2006 ) . Interleukin-18 as a potential therapeutic target in chronic autoimmune/inflammatory conditions . Expert Opinion on Biological Therapy vol. 7 , ( 1 ) 31 - 40 .
Bombardieri M, Barone F, Carlucci F, Proctor G, van de Loo FA, van den Berg WB, Botto M, Valesini G et al. ( 2006 ) . The IL-18/IL-18R axis is significantly up-regulated in submandibular glands in the nod mouse model of Sjogren's syndrome and is associated with an ongoing TH1-mediated inflammation . RHEUMATOLOGY . vol. 45 , I156 - I156 .
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