Publications: Dr Daniele Bergamaschi

Ross R, Guo Y, Walker RN, Bergamaschi D, Shaw TJ, Connelly JT ( 2024 ) . Biomechanical Activation of Keloid Fibroblasts Promotes Lysosomal Remodeling and Exocytosis . Journal of Investigative Dermatology vol. 144 , ( 12 ) 2730 - 2741 .

Bergamaschi D ( 2024 ) . Autophagy Modulation in Endothelial Hyperglycemia-Induced Wound-Healing Impairment . Journal of Investigative Dermatology vol. 144 , ( 5 ) 929 - 930 .

Bergamaschi D ( 2024 ) . Improving cancer stem cells killing in malignant melanoma . British Journal of Dermatology vol. 190 , ( 5 ) 615 - 616 .

Uddin N, Ostano P, Chiorino G, di Domizio J, Gilliet M, Philpott M, Hannen R, Bergamaschi D ( 2023 ) . O09 Dynamic impact of chronic inflammation on epidermal autophagy pathway . British Journal of Dermatology vol. 189 , ( 1 ) e7 - e8 .

Maurichi A, Barretta F, Patuzzo R, Miceli R, Gallino G, Mattavelli I, Leva A, Harwood C et al. ( 2023 ) . Similar local recurrence and survival in patients with T1 radial growth phase melanoma on head and neck treated with 5 or 10 mm margins: A retrospective study . Journal of the European Academy of Dermatology and Venereology vol. 37 , ( 7 ) 1318 - 1326 .

Uddin N, Ostano P, Chiorino G, Philpott M, Hannen R, Bergamaschi D ( 2022 ) . 347 Chronic Inflammation of Keratinocytes Leads to Autophagy Impairment in Psoriasis . Journal of Investigative Dermatology vol. 142 , ( 12 )

Ross R, Bergamaschi D, Shaw TJ, Connelly J ( 2022 ) . 597 Altered mechano-sensing and autophagy in keloid dermal fibroblasts . Journal of Investigative Dermatology vol. 142 , ( 12 )

Begum Uddin N, Ostano P, Chiorino G, Philpott M, Hannen R, Bergamaschi D ( 2022 ) . ESDR347 - Chronic Inflammation of Keratinocytes Leads to Autophagy Impairment in Psoriasis .

Chikh A, Sanzà P, Raimondi C, Akinduro O, Warnes G, Chiorino G, Byrne C, Harwood CA et al. ( 2022 ) . Retraction: iASPP is a novel autophagy inhibitor in keratinocytes . Journal of Cell Science vol. 135 , ( 14 )

Uddin NB, Asher S, Mannella V, Varahan B, Purdie K, Leigh I, Philpott M, Hannen R et al. ( 2022 ) . Autophagy impairment and dysfunctional stress response in the pathophysiology of psoriasis . BRITISH JOURNAL OF DERMATOLOGY . vol. 187 , E26 - E26 .

Uddin N, Ostano P, Chiorino G, Philpott M, Hannen R, Bergamaschi D ( 2022 ) . Chronic inflammation impairs autophagy in psoriasis . BRITISH JOURNAL OF DERMATOLOGY . vol. 186 , E220 - E221 .

Scatolini M, Patel A, Grosso E, Mello‐Grand M, Ostano P, Coppo R, Vitiello M, Venesio T et al. ( 2022 ) . GJB5 association with BRAF mutation and survival in cutaneous malignant melanoma* . British Journal of Dermatology vol. 186 , ( 1 ) 117 - 128 .

Bergamaschi D ( 2021 ) . Autophagy protects from photoageing in skin fibroblasts . British Journal of Dermatology vol. 186 , ( 2 ) 211 - 212 .

Mannella V, Boehm K, Celik S, Ali T, Mirza AN, Hasnaouy ME, Kaffa A, Lyu Y et al. ( 2021 ) . Growth and viability of cutaneous squamous cell carcinoma cell lines display different sensitivities to isoform-specific phosphoinositide 3-kinase inhibitors . International Journal of Molecular Sciences vol. 22 , ( 7 )

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH et al. ( 2021 ) . Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹ . Autophagy vol. 17 , ( 1 ) 1 - 382 .

Maurichi A, Miceli R, Patuzzo R, Barretta F, Gallino G, Mattavelli I, Barbieri C, Leva A et al. ( 2020 ) . Analysis of Sentinel Node Biopsy and Clinicopathologic Features as Prognostic Factors in Patients With Atypical Melanocytic Tumors . Journal of the National Comprehensive Cancer Network vol. 18 , ( 10 ) 1327 - 1336 .

Maurichi A, Miceli R, Eriksson H, Newton-Bishop J, Nsengimana J, Chan M, Hayes AJ, Heelan K et al. ( 2020 ) . Reply to E. Hindié . Journal of Clinical Oncology vol. 38 , ( 27 ) 3238 - 3240 .

Patel A, Garcia LF, Mannella V, Gammon L, Borg T-M, Maffucci T, Scatolini M, Chiorino G et al. ( 2020 ) . Targeting p63 Upregulation Abrogates Resistance to MAPK Inhibitors in Melanoma . Cancer Research vol. 80 , ( 12 ) 2676 - 2688 .

Maurichi A, Miceli R, Eriksson H, Newton-Bishop J, Nsengimana J, Chan M, Hayes AJ, Heelan K et al. ( 2020 ) . Factors Affecting Sentinel Node Metastasis in Thin (T1) Cutaneous Melanomas: Development and External Validation of a Predictive Nomogram . J Clin Oncol vol. 38 , ( 14 ) 1591 - 1601 .

Rehman A, Cai Y, Hünefeld C, Jedličková H, Huang Y, Teck Teh M, Sharif Ahmad U, Uttagomol J et al. ( 2019 ) . The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53 . Cell Death & Disease vol. 10 , ( 10 )

Scatolini M, Grosso E, Mello-Grand M, Ostano P, Coppo R, Patel A, Vitiello M, Venesio T et al. ( 2019 ) . GJB5 association with BRAF mutation and survival in cutaneous melanoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . Conference: ESDR 2019 Bordeaux September 2019 vol. 139 , S296 - S296 .

Bergamaschi D, Vossenkamper A, Lee WYJ, Wang P, Bochukova E, Warnes G ( 2019 ) . Simultaneous polychromatic flow cytometric detection of multiple forms of regulated cell death . Apoptosis

Robinson DJ, Patel A, Purdie KJ, Wang J, Rizvi H, Hufbauer M, Ostano P, Akgül B et al. ( 2019 ) . Epigenetic Regulation of iASPP-p63 Feedback Loop in Cutaneous Squamous Cell Carcinoma . Journal of Investigative Dermatology vol. 139 , ( 8 ) 1658 - 1671.e8 .

Jiang Q, Alabi I-KA, Bergamaschi D ( 2019 ) . Dissecting the integrity of epidermal autophagy in human eczema samples . BRITISH JOURNAL OF DERMATOLOGY . vol. 180 , E207 - E208 .

Mannella V, Bergamaschi D, Harwood C, Maffucci T ( 2019 ) . Targeting selective phosphoinositide-3-kinase isoforms as a novel strategy in cutaneous squamous cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 180 , E213 - E213 .

Borg T-M, PATEL A, BERGAMASCHI D, HARWOOD CA ( 2018 ) . Targeting p63 upregulation may prevent the development of MAPK inhibitor resistance in melanoma . Conference: MAP 2018 - Molecular Analysis for Personalised Therapy

Rehman A, Cai Y, Jedliková H, Harwood C, Bergamaschi D, Wan H ( 2018 ) . 1347 Desmoglein-3 acts as an anti-stress protein via suppression of p53 . Journal of Investigative Dermatology vol. 138 , ( 5 ) S229 - S229 .

Rehman A, Cai Y, Jedlikova H, Harwood C, Bergamaschi D, Wan H ( 2018 ) . Desmoglein-3 acts as an anti-stress protein via suppression of p53 . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 138 , S229 - S229 .

Knowles O, Doldan P, Hillier-Richardson I, Lunt S, Gammon L, Youssef G, Harwood C, Mackenzie I et al. ( 2018 ) . Identification of a novel cancer stem cell subpopulation in melanoma pathological specimens . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E411 - E411 .

Rehman A, Cai Y, Jedlickova H, Harwood C, Bergamaschi D, Wan H ( 2018 ) . Novel role of desmoglein-3 acting as a negative regulator of p53 . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E417 - E418 .

Patel AV, Borg T-M, Rodolfo M, Posch C, Harwood C, Bergamaschi D ( 2018 ) . Targeting p63 upregulation may prevent development of mitogen-activated protein kinase inhibitor resistance in melanoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E397 - E398 .

Rogerson C, Bergamaschi D, O'Shaughnessy RFL ( 2017 ) . Uncovering mechanisms of nuclear degradation in keratinocytes: A paradigm for nuclear degradation in other tissues . Nucleus1 - 9 .

Patel A, Harwood CA, Bergamaschi D ( 2017 ) . p63 signalling in BRAF inhibitor resistant melanoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . Conference: European Society of Investigative Dermatology 2017 vol. 137 , S285 - S285 .

Akinduro O, Harwood CA, O'Shaughnessy R, Bergamaschi D ( 2016 ) . Epidermal autophagy and nucleophagy . JOURNAL OF INVESTIGATIVE DERMATOLOGY . Conference: European Society of Investigative Dermatology vol. 136 , S183 - S183 .

Patel A, Harwood C, Bergamaschi D ( 2016 ) . P63 contributes to acquired BRAF inhibitor resistance in melanoma . BRITISH JOURNAL OF DERMATOLOGY . Conference: British Society of Investigative Dermatology 2016 vol. 174 , E52 - E52 .

Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP et al. ( 2016 ) . Constitutive Autophagy and Nucleophagy during Epidermal Differentiation . Journal of Investigative Dermatology vol. 136 , ( 7 ) 1460 - 1470 .

Chikh A, Ferro R, Abbott JJ, Piñeiro R, Buus R, Iezzi M, Ricci F, Bergamaschi D et al. ( 2016 ) . Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression . Oncotarget vol. 7 , ( 14 ) 18325 - 18345 .

( 2016 ) . Erratum . Autophagy vol. 12 , ( 2 ) 443 - 443 .

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM et al. ( 2016 ) . Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) . Autophagy vol. 12 , ( 1 ) 1 - 222 .

Robinson D, Harwood C, Bergamaschi D ( 2015 ) . Dissecting the role of iASPP, a novel regulator of epidermal homeostasis, in keratinocyte skin carcinogenesis . BRITISH JOURNAL OF DERMATOLOGY . vol. 172 , E42 - E42 .

Maurichi A, Miceli R, Camerini T, Mariani L, Patuzzo R, Ruggeri R, Gallino G, Tolomio E et al. ( 2014 ) . Prediction of survival in patients with thin melanoma: results from a multi-institution study . J Clin Oncol vol. 32 , ( 23 ) 2479 - 2485 .

Chikh A, Sanza P, Raimondi C, Akinduro O, Warnes G, Chiorino G, Byrne C, Harwood CA et al. ( 2014 ) . IASPP is a novel autophagy mudulator in keratinocytes . J Cell Science vol. 127 , ( 14 ) 3079 - 3093 .

Bergamaschi D ( 2014 ) . Is Mcl-1L the new anti-apoptotic effector of B-RAFV(600E) in melanoma? . Exp Dermatol vol. 23 , ( 2 )

Botti E, Fausti F, Spallone G, Levesque M, Bergamaschi D, Guerrini L, Dummer R, Costanzo A ( 2014 ) . BRAF inhibitors reactivate tumor suppressive and oncogenic p53 activities in melanoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 134 , S90 - S90 .

Matin RN, Chikh A, Chong SLP, Mesher D, Graf M, Sanza' P, Senatore V, Scatolini M et al. ( 2013 ) . p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis . J Exp Med vol. 210 , ( 3 ) 581 - 603 .

BERGAMASCHI D, Wang, Y, Godin-Heymann N, Dan Wang X, Llanos S, Lu X ( 2013 ) . ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells . Cell Death and Differentiation vol. 20 , ( 4 ) 525 - 534 .

Akinduro O, Sully K, Chikh A, O'shaughnessy RF, Bergamaschi D, Harwood CA, Philpott MP, Byrne C ( 2013 ) . Constitutive autophagy as a terminal differentiation mechanism . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S127 - S127 .

Chikh A, Harwood C, Bergamaschi D ( 2013 ) . IASPP is a novel autophagy inhibitor in keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S126 - S126 .

Szentpetery Z, Lovat PE, Bergamaschi D, O'Toole EA ( 2013 ) . The receptor tyrosine kinase, Axl, as a therapeutic target in malignant melanoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S240 - S240 .

Wang H, Lee S, Nigro CL, Lattanzio L, Merlano M, Monteverde M, Matin R, Purdie K et al. ( 2012 ) . NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity . Br J Cancer vol. 106 , ( 8 ) 1446 - 1452 .

Akinduro O, Sully K, O'Shaughnessy R, Harwood CA, Bergamaschi D, Byrne C ( 2012 ) . A Novel Mechanism of Keratinocyte Terminal Differentiation - Autophagy? . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 132 , S78 - S78 .

Akinduro O, Sully K, O'Shaughnessy RFL, Harwood CA, Bergamaschi D, Byrne C ( 2012 ) . Autophagy in epidermis . BRITISH JOURNAL OF DERMATOLOGY . vol. 166 , e31 - e31 .

Matin RN, Chikh A, Chong SLP, Harwood C, Bergamaschi D ( 2012 ) . p63, a p53 repressor in melanoma which confers chemoresistance and a poor prognosis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 132 , S127 - S127 .

Matin RN, Chikh A, Law S, Harwood CA, Bergamaschi D ( 2012 ) . p63, an alternative p53 repressor in melanoma which confers chemoresistance and a poor prognosis . BRITISH JOURNAL OF DERMATOLOGY . vol. 166 , e15 - e15 .

Chikh A, Matin RNH, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M et al. ( 2011 ) . iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia . EMBO J vol. 30 , ( 20 ) 4261 - 4273 .

Chikh A, Bergamaschi D ( 2011 ) . iASPP mediates regulation of autophagy in keratinocytes . BRITISH JOURNAL OF DERMATOLOGY . vol. 164 , 914 - 914 .

Chikh A, Bergamaschi D ( 2011 ) . iASPP/p63 auto-regulatory feedback loop is essential for epithelial integrity and autophagy . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 131 , S56 - S56 .

Llanos S, Royer C, Lu M, Bergamaschi D, Lee WH, Lu X ( 2011 ) . Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif . J Biol Chem. vol. 286 , ( 50 ) 43039 - 43044 .

Chikh A, Matin R, Harwood CA, Bergamaschi D ( 2010 ) . iASPP: a novel and essential key regulator of skin homeostasis . BRITISH JOURNAL OF DERMATOLOGY . vol. 162 , 914 - 914 .

Matin RN, Chikh A, Warnes G, Proby CM, Leigh IM, Harwood CA, Bergamaschi D ( 2010 ) . p63 is implicated in apoptotic dysregulation in melanoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 162 , 921 - 921 .

Chikh A, Bergamaschi D ( 2009 ) . A novel Role of iASPP, a key regulator in skin development . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 129 , S57 - S57 .

Matin R, Hajji N, Chikh A, Harwood CA, Bergamaschi D ( 2008 ) . P63 is implicated in apoptotic deregulation in melanoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 158 , 911 - 912 .

Philpott MP, Bergamaschi D, Storey A ( 2007 ) . Models for Skin Cancer . The Cancer Handbook , Wiley

Bell HS, Dufes C, O'Prey J, Crighton D, Bergamaschi D, Lu X, Schatzlein AG, Vousden KH et al. ( 2007 ) . A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo . J CLIN INVEST vol. 117 , ( 4 ) 1008 - 1018 .

Leverrier S, Bergamaschi D, Ghali L, Ola A, Warnes G, Akgul B, Blight K, Garcia-Escudero R et al. ( 2007 ) . Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria . APOPTOSIS vol. 12 , ( 3 ) 549 - 560 .

Gubser C, Bergamaschi D, Hollinshead M, Lu X, van Kuppeveld FJM, Smith GL ( 2007 ) . A new inhibitor of apoptosis from vaccinia virus and eukaryotes . PLoS Pathog vol. 3 , ( 2 )

Bergamaschi D, Samuels Y, Sullivan A, Zvelebil M, Breyssens H, Bisso A, Del Sal G, Syed N et al. ( 2006 ) . iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72 polymorphic p53 . NAT GENET vol. 38 , ( 10 ) 1133 - 1141 .

Bergamaschi D, Samuels Y, Zhong S, Lu X ( 2005 ) . Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradation . ONCOGENE vol. 24 , ( 23 ) 3836 - 3841 .

Zhang WQ, Bergamaschi D, Jin BQ, Lu X ( 2005 ) . Posttranslational modifications of p27kip1 determine its binding specificity to different cyclins and cyclin-dependent kinases in vivo . BLOOD vol. 105 , ( 9 ) 3691 - 3698 .

Slee EA, Gillotin S, Bergamaschi D, Royer C, Llanos S, Ali S, Jin B, Trigiante G et al. ( 2004 ) . The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization . Oncogene vol. 23 , ( 56 ) 9007 - 9016 .

Sullivan A, Syed N, Gasco M, Bergamaschi D, Trigiante G, Attard M, Hiller L, Farrell PJ et al. ( 2004 ) . Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo . Oncogene vol. 23 , ( 19 ) 3328 - 3337 .

Bergamaschi D, Samuels Y, Jin B, Duraisingham S, Crook T, Lu X ( 2004 ) . ASPP1 and ASPP2: common activators of p53 family members . Mol Cell Biol vol. 24 , ( 3 ) 1341 - 1350 .

Bergamaschi D, Gasco M, Hiller L, Sullivan A, Syed N, Trigiante G, Yulug I, Merlano M et al. ( 2003 ) . p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis . Cancer Cell vol. 3 , ( 4 ) 387 - 402 .

Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh J-K, O'Connor DJ, Zhong S et al. ( 2003 ) . iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human . Nat Genet vol. 33 , ( 2 ) 162 - 167 .

Samuels-Lev Y, O'Connor DJ, Bergamaschi D, Trigiante G, Hsieh JK, Zhong S, Campargue I, Naumovski L et al. ( 2001 ) . ASPP proteins specifically stimulate the apoptotic function of p53 . Mol Cell vol. 8 , ( 4 ) 781 - 794 .

Erba E, Bergamaschi D, Bassano L, Damia G, Ronzoni S, Faircloth GT, D'Incalci M ( 2001 ) . Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action . Eur J Cancer vol. 37 , ( 1 ) 97 - 105 .

Erba E, Bergamaschi D, Bassano L, Ronzoni S, Di Liberti G, Muradore I, Vignati S, Faircloth G et al. ( 2000 ) . Isolation and characterization of an IGROV-1 human ovarian cancer cell line made resistant to Ecteinascidin-743 (ET-743) . British Journal of Cancer vol. 82 , ( 10 ) 1732 - 1739 .

Erba E, Bergamaschi D, Ronzoni S, Faretta M, Taverna S, Bonfanti M, Catapano CV, Faircloth G et al. ( 1999 ) . Mode of action of thiocoraline, a natural marine compound with anti-tumour activity . British Journal of Cancer vol. 80 , ( 7 ) 971 - 980 .

Mologni L, Ponzanelli I, Bresciani F, Sardiello G, Bergamaschi D, Giannı́ M, Reichert U, Rambaldi A et al. ( 1999 ) . The Novel Synthetic Retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) Causes Apoptosis in Acute Promyelocytic Leukemia Cells Through Rapid Activation of Caspases . Blood vol. 93 , ( 3 ) 1045 - 1061 .

Mologni L, Ponzanelli I, Bresciani F, Sardiello G, Bergamaschi D, Giannı́ M, Reichert U, Rambaldi A et al. ( 1999 ) . The novel synthetic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) causes apoptosis in acute promyelocytic leukemia cells through rapid activation of caspases . Blood vol. 93 , ( 3 ) 1045 - 1061 .

Bergamaschi D, Ronzoni S, Taverna S, Faretta M, Feudis PD, Faircloth G, Jimeno J, Erba E et al. ( 1998 ) . Cell cycle perturbations and apoptosis induced by isohomohalichondrin B (IHB), a natural marine compound . British Journal of Cancer vol. 79 , ( 2 ) 267 - 277 .

Faretta M, Bergamaschi D, Taverna S, Ronzoni S, Pantarotto M, Mascellani E, Cappella P, Ubezio P et al. ( 1998 ) . Characterization of cyclin B1 expression in human cancer cell lines by a new three‐parameter BrdUrd/Cyclin B1/DNA analysis . Cytometry vol. 31 , ( 1 ) 53 - 59 .

Ghielmini M, Colli E, Erba E, Bergamaschi D, Pampallona S, Jimeno J, Faircloth G, Sessa C ( 1998 ) . In vitro schedule-dependency of myelotoxicity and cytotoxicity of Ecteinascidin 743 (ET-743) . Annals of Oncology vol. 9 , ( 9 ) 989 - 993 .

Erba E, Bergamaschi D, Ronzoni S, Faretta M, Bassano L, Cappella P, Valoti G, Giavazzi R et al. ( 1998 ) . Mode of action of Ecteinascidin 743, a natural marine compound with antitumoral activity . ANNALS OF ONCOLOGY vol. 9 , 139 - 139 .

Erba E, Bergamaschi D, Ronzoni S, Faretta M, Bassano L, Vikhanskaya F, Jimeno J, Faircloth G et al. ( 1998 ) . Thiocoraline, a novel DNA polymerase inhibitor with a higher cytotoxic potency against cancer cells with mutated or inactivated p53 . ANNALS OF ONCOLOGY vol. 9 , 141 - 141 .

Desiderio M, Bergamaschi D, Mascellani E, De Feudis P, Erba E, D'Incalci M ( 1997 ) . Treatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors . British Journal of Cancer vol. 75 , ( 7 ) 1028 - 1034 .

Faretta M, Bergamaschi D, Ronzoni S, D'Incalci M, Erba E ( 1997 ) . Differences in cyclin B1 expression in cells blocked in the G2M phase after treatment with anticancer agent. New three-parametric flow cytometric analysis . European Journal of Histochemistry . vol. 41 Suppl 2 , 73 - 74 .

Bergamaschi D, Faretta M, Ronzoni S, Taverna S, De Feudis P, Bonfanti M, Guidi G, Faircloth M et al. ( 1997 ) . Flow cytometric analysis of cell cycle phase perturbations induced by Thiocoraline, a new marine-derived anticancer compound . European Journal of Histochemistry . vol. 41 Suppl 2 , 63 - 64 .