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Research

Publications: Dr Esra Aksoy-Poister

Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS et al. ( 2021 ) . Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation . Immunity vol. 54 , ( 9 ) 1989 - 2004.e9 .
Thibault B, Ramos‐Delgado F, Pons‐Tostivint E, Therville N, Cintas C, Arcucci S, Cassant‐Sourdy S, Reyes‐Castellanos G et al. ( 2021 ) . Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component . EMBO Molecular Medicine vol. 13 , ( 7 )
Wood TE, Aksoy E, Hachani A ( 2020 ) . From Welfare to Warfare: The Arbitration of Host-Microbiota Interplay by the Type VI Secretion System . Frontiers in Cellular and Infection Microbiology vol. 10 ,
Ferguson MS, Chard Dunmall LS, Gangeswaran R, Marelli G, Tysome JR, Burns E, Whitehead MA, Aksoy E et al. ( 2020 ) . Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus . Molecular Therapy vol. 28 , ( 5 ) 1263 - 1275 .
Aksoy E ( 2019 ) . TLRs toll for Tregs . Journal of Leukocyte Biology vol. 106 , ( 6 ) 1193 - 1195 .
Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X et al. ( 2019 ) . Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation . Cell Reports vol. 27 , ( 5 ) 1461 - 1471.e4 .
Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J et al. ( 2019 ) . Erratum: Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR (Cell (2019) 177(5) (1201–1216.e19), (S0092867419302806), (10.1016/j.cell.2019.03.018)) . Cell vol. 178 , ( 1 ) 263 - 263 .
Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J et al. ( 2019 ) . Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR . Cell vol. 177 , ( 5 ) 1201 - 1216.e19 .
Aksoy E, Saveanu L, Manoury B ( 2018 ) . The Isoform Selective Roles of PI3Ks in Dendritic Cell Biology and Function . Frontiers in Immunology vol. 9 ,
Simeoli R, Mattace Raso G, Lama A, Pirozzi C, Santoro A, Di Guida F, Sanges M, Aksoy E et al. ( 2015 ) . Preventive and Therapeutic Effects of Lactobacillus Paracasei B21060–Based Synbiotic Treatment on Gut Inflammation and Barrier Integrity in Colitic Mice 1–3 . Journal of Nutrition vol. 145 , ( 6 ) 1202 - 1210 .
Bontems P, Aksoy E, Burette A, Segers V, Deprez C, Mascart F, Cadranel S ( 2014 ) . NF‐κB Activation and Severity of Gastritis in Helicobacter pylori‐Infected Children and Adults . Helicobacter vol. 19 , ( 3 ) 157 - 167 .
Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno-Martin I et al. ( 2013 ) . Erratum: Corrigendum: The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock . Nature Immunology vol. 14 , ( 8 ) 877 - 877 .
Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno IM et al. ( 2012 ) . The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock . Nature Immunology vol. 13 , ( 11 ) 1045 - 1054 .
AKSOY-POISTER E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno IM et al. ( 2012 ) . The p110´ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock . Nat Immunol. vol. 13 , ( 11 ) 1045 - 1054 .
Johnson J, Molle C, Aksoy E, Goldman M, Goriely S, Willems F ( 2011 ) . A conventional protein kinase C inhibitor targeting IRF-3-dependent genes differentially regulates IL-12 family members . Molecular Immunology vol. 48 , ( 12-13 ) 1484 - 1493 .
Langlet C, Springael C, Johnson J, Thomas S, Flamand V, Leitges M, Goldman M, Aksoy E et al. ( 2010 ) . PKC‐α controls MYD88‐dependent TLR/IL‐1R signaling and cytokine production in mouse and human dendritic cells . European Journal of Immunology vol. 40 , ( 2 ) 505 - 515 .
Goriely S, Aksoy E, De Wit D, Goldman M, Willems F ( 2008 ) . Toll-like Receptor Responses in Neonatal Dendritic Cells . Hematology, Immunology and Infectious Disease: Neonatology Questions and Controversies ,
Johnson J, Albarani V, Nguyen M, Goldman M, Willems F, Aksoy E ( 2007 ) . Protein Kinase Cα Is Involved in Interferon Regulatory Factor 3 Activation and Type I Interferon-β Synthesis* . Journal of Biological Chemistry vol. 282 , ( 20 ) 15022 - 15032 .
Moore F, Buonocore S, Aksoy E, Ouled-Haddou N, Goriely S, Lazarova E, Paulart F, Heirman C et al. ( 2007 ) . An Alternative Pathway of NF-κB Activation Results in Maturation and T Cell Priming Activity of Dendritic Cells Overexpressing a Mutated IκBα . The Journal of Immunology vol. 178 , ( 3 ) 1301 - 1311 .
Aksoy E, Albarani V, Nguyen M, Laes J-F, Ruelle J-L, De Wit D, Willems F, Goldman M et al. ( 2006 ) . Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells . Blood vol. 109 , ( 7 ) 2887 - 2893 .
Aksoy E, Berghe WV, Detienne S, Amraoui Z, Fitzgerald KA, Haegeman G, Goldman M, Willems F ( 2005 ) . Inhibition of phosphoinositide 3‐kinase enhances TRIF‐dependent NF‐κB activation and IFN‐β synthesis downstream of Toll‐like receptor 3 and 4 . European Journal of Immunology vol. 35 , ( 7 ) 2200 - 2209 .
Aksoy E, Zouain CS, Vanhoutte F, Fontaine J, Pavelka N, Thieblemont N, Willems F, Ricciardi-Castagnoli P et al. ( 2004 ) . Double-stranded RNAs from the Helminth Parasite Schistosoma Activate TLR3 in Dendritic Cells* . Journal of Biological Chemistry vol. 280 , ( 1 ) 277 - 283 .
Vosters O, Beuneu C, Nagy N, Movahedi B, Aksoy E, Salmon I, Pipeleers D, Goldman M et al. ( 2004 ) . CD40 expression on human pancreatic duct cells: role in nuclear factor-kappa B activation and production of pro-inflammatory cytokines . Diabetologia vol. 47 , ( 4 ) 660 - 668 .
Aksoy E, Goldman M, Willems F ( 2004 ) . Protein kinase C epsilon: a new target to control inflammation and immune-mediated disorders . The International Journal of Biochemistry & Cell Biology vol. 36 , ( 2 ) 183 - 188 .
Tonon S, Goriely S, Aksoy E, Pradier O, Del Giudice G, Trannoy E, Willems F, Goldman M et al. ( 2002 ) . Bordetella pertussis toxin induces the release of inflammatory cytokines and dendritic cell activation in whole blood: impaired responses in human newborns . European Journal of Immunology vol. 32 , ( 11 ) 3118 - 3125 .
Aksoy E, Amraoui Z, Goriely S, Goldman M, Willems F ( 2002 ) . Critical role of protein kinase C ϵ for lipopolysaccharide‐induced IL‐12 synthesis in monocyte‐derived dendritic cells . European Journal of Immunology vol. 32 , ( 11 ) 3040 - 3049 .
Ismaili J, Rennesson J, Aksoy E, Vekemans J, Vincart B, Amraoui Z, Van Laethem F, Goldman M et al. ( 2002 ) . Monophosphoryl Lipid A Activates Both Human Dendritic Cells and T Cells . The Journal of Immunology vol. 168 , ( 2 ) 926 - 932 .
Vanderheyde N, Aksoy E, Amraoui Z, Vandenabeele P, Goldman M, Willems F ( 2001 ) . Tumoricidal Activity of Monocyte-Derived Dendritic Cells: Evidence for a Caspase-8-Dependent, Fas-Associated Death Domain-Independent Mechanism . The Journal of Immunology vol. 167 , ( 7 ) 3565 - 3569 .
Willems F, Amraoui Z, Vanderheyde N, Verhasselt V, Aksoy E, Scaffidi C, Peter ME, Krammer PH et al. ( 2000 ) . Expression of c-FLIP(L) and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide . Blood vol. 95 , ( 11 ) 3478 - 3482 .