Publications:  Mrs Susan Shaw-Hawkins

Song C, Burgess S, Eicher JD, O'Donnell CJ, Johnson AD, Huang J, Sabater-Lleal M, Asselbergs FW et al.(2017). Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease. Journal of the American Heart Association vol. 6, (6)

MUNROE PB(2016). Trans-ancestry meta-analyses identify novel rare and common variants associated with blood pressure and hypertension. Nature Genetics

Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE et al.(2016). Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Journal of Medical Genetics

Bodea CA, Neale BM, Ripke S, Daly MJ, Devlin B, Roeder K(2016). A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies. American Journal of Human Genetics vol. 98, (5) 857-868.

Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A et al.(2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun vol. 7,

Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C et al.(2015). A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet vol. 11, (3)

Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K et al.(2014). Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun vol. 5,

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al. (2013). ADAMTS7 CLEAVAGE AND VASCULAR SMOOTH MUSCLE CELL MIGRATION IS AFFECTED BY A CORONARY ARTERY DISEASE ASSOCIATED VARIANT. HEART. vol. 99, A5-U20.

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al.(2013). ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant. American Journal of Human Genetics vol. 92, (3) 366-374.

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al.(2013). ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant. Am J Hum Genet vol. 92, (3) 366-374.

Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I et al.(2011). Blood pressure loci identified with a gene-centric array. Am J Hum Genet vol. 89, (6) 688-700.

International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV et al.(2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature vol. 478, (7367) 103-109.

Putku M, Kepp K, Org E, Sõber S, Comas D, Viigimaa M, Veldre G, Juhanson P et al.(2011). Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans. Hum Mutat vol. 32, (7) 806-814.

Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC et al.(2011). Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet vol. 20, (11) 2273-2284.

Johnson T, Shaw-Hawkins S, Howard P, Lathrop M, Stanton A, Shields D, Poulter N, Sever P et al.(2010). A novel gene locus for blood pressure variability identified by genomewide association scanning in the Anglo-Scandinavian Cardiac Outcome Trial. J HUM HYPERTENS vol. 24, (10) 694-694.

Craddock N, Hurles ME, Cardin N, Pearson RD, Plagnol V, Robson S, Vukcevic D, Barnes C et al.(2010). Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. NATURE vol. 464, (7289) 713-U86.

Sõber S, Org E, Kepp K, Juhanson P, Eyheramendy S, Gieger C, Lichtner P, Klopp N et al.(2009). Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array. PLoS One vol. 4, (6)

Org E, Eyheramendy S, Juhanson P, Gieger C, Lichtner P, Klopp N, Veldre G, Döring A et al.(2009). Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. Hum Mol Genet vol. 18, (12) 2288-2296.

Newhouse S, Farrall M, Wallace C, Hoti M, Burke B, Howard P, Onipinla A, Lee K et al.(2009). Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion. PLoS One vol. 4, (4)

Caulfield MJ, Munroe PB, O'Neill D, Witkowska K, Charchar FJ, Doblado M, Evans S, Eyheramendy S et al.(2008). SLC2A9 is a high-capacity urate transporter in humans. PLoS Med vol. 5, (10)

Brown MJ, Newhouse S, Wallace C, Marcano AC, Shaw-Hawkins S, Howard P, Onipinla A, Dobson R et al. (2008). Systematic analysis of 123 candidate genes reveals two novel genes for hypertension. HYPERTENSION. vol. 52, 764-765.

WALLACE C, Wellcome Trust CCC(2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature vol. 447, (7145) 661-678.

McCarthy LC, Hosford DA, Riley JH, Bird MI, White NJ, Hewett DR, Peroutka SJ, Griffiths LR et al.(2001). Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine. Genomics vol. 78, (3) 135-149.

Rallan R, McCarthy LC, Montgomery DS, Doreen DG, Cantone KL, Christodoulou C, Cutts RJ, Donnelly C et al. (2000). Semi-automated oligo ligation assay (OLA) with ABI3700 sequencer allele resolution and complete sample tracking. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 67, 265-265.

Shaw-Ponter S, Mills G, Robertson M, Bostwick RD, Hardy GW, Young RJ(1996). Acyl carbamate directing groups in nucleoside synthesis: Applications in the synthesis of 2′-deoxy-5-ethyl-4′-thiouridine. Tetrahedron Letters vol. 37, (11) 1867-1870.

Shaw-Ponter S, Rider P, Young RJ(1996). New synthesis of both D- and L-3-O-carbamoyl-2-deoxy-4-thioribosides, substrates for β-selective glycosylations. Tetrahedron Letters vol. 37, (11) 1871-1874.

Mann J, Tench AJ, Weymouth-Wilson AC, Shaw-Ponter S, Young RJ(1995). Two synthetic routes to 2′,3′dideoxy-3′-C-(hydroxymethyl) -4′-thionucleosides. Journal of the Chemical Society, Perkin Transactions 1 (6) 677-681.

Young RJ, Shaw-Ponter S, Thomson JB, Miller JA, Cumming JG, Pugh AW, Rider P(1995). Synthesis and antiviral evaluation of enantiomeric 2′,3′-dideoxy- and 2′,3′-didehydro-2′,3′-dideoxy-4′-thionucle osides. Bioorganic and Medicinal Chemistry Letters vol. 5, (22) 2599-2604.

Young RJ, Shaw-Ponter S, Hardy GW, Mills G(1994). β-Anomer selectivity in 2′-deoxynucleoside synthesis: A novel approach using an acyl carbamate directing group. Tetrahedron Letters vol. 35, (46) 8687-8690.