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Publications:  Dr Trinidad Montero Melendez

Montero Melendez T, Nagano A, Chelala C, Filer A, Buckley CD, Perretti M(2020). Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis. Nature Communications vol. 11, (1) Article 745,
10.1038/s41467-020-14421-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62896
MONTERO MELENDEZ T(2018). MAY INFLAMMATION BE WITH YOU!. Frontiers For Young Minds
10.3389/frym.2018.00051
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55608
Patruno S, Garrido-Mesa J, Romano M, PERRETTI M, MONTERO MELENDEZ T(2018). Ligand bias and its association with pro-resolving actions of melanocortin drugs. Frontiers in Pharmacology vol. 9, (919)
10.3389/fphar.2018.00919
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43647
Perretti M, Montero-Melendez T(2017). Resolution in an 'over-inflamed' era. Biochemist vol. 39, (4) 4-7.
10.1042/bio03904004
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43048
Kaneva MK, Greco KV, Headland SE, Montero-Melendez T, Mori P, Greenslade K, Pitzalis C, Moore A et al.(2017). Identification of novel chondroprotective mediators in resolving inflammatory exudates. Journal of Immunology vol. 198, (7) 2876-2885.
10.4049/jimmunol.1601111
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22622
Montero-Melendez T, Forfar RAE, Cook JM, Jerman JC, Taylor DL, Perretti M(2017). Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3. Cellular and Molecular Life Sciences vol. 74, (7) 1335-1345.
10.1007/s00018-016-2419-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19607
Simeoli R, Mattace Raso G, Pirozzi C, Lama A, Santoro A, Russo R, Montero-Melendez T, Berni Canani R et al.(2017). An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis. British Journal of Pharmacology vol. 174, (11) 1484-1496.
10.1111/bph.13637
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43044
Madeira MFM, Queiroz-Junior CM, Montero-Melendez T, Werneck SMC, Correa JD, Soriani FM, Garlet GP, Souza DG et al.(2016). Melanocortin agonism as a viable strategy to control alveolar bone loss induced by oral infection. The FASEB Journal
10.1096/fj.201600790R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16159
MONTERO MELENDEZ T, Buckley CD, Filer A, Turner JD, Perretti M (2016). TARGETING SYNOVIAL FIBROBLASTS WITH MELANOCORTIN DRUGS. ANNALS OF THE RHEUMATIC DISEASES. Conference: Annual European Congress of Rheumatology EULAR 2016 vol. 75, 923-923.
10.1136/annrheumdis-2016-eular.3231
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62897
Perretti M, Leroy X, Bland EJ, Montero-Melendez T(2015). Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation. Trends in Pharmacological Sciences vol. 36, (11) 737-755.
10.1016/j.tips.2015.07.007
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43045
Montero-Melendez T(2015). ACTH: The forgotten therapy. Semin Immunol vol. 27, (3) 216-226.
10.1016/j.smim.2015.02.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43047
Montero-Melendez T, Gobbetti T, Cooray SN, Jonassen TE, Perretti M(2015). Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol vol. 194, (7) 3381-3388.
10.4049/jimmunol.1402645
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17994
Haas R, Smith J, Rocher-Ros V, Nadkarni S, Montero-Melendez T, D¿Acquisto F, Bland EJ, Bombardieri M et al.(2015). Lactate regulates metabolic and proinflammatory circuits in control of T cell migration and effector functions. PLoS Biology vol. 13, (7)
10.1371/journal.pbio.1002202
https://qmro.qmul.ac.uk/xmlui/handle/123456789/8009
Haas R, Smith J, Rocher-Ros V, Montero-Melendez T, D'Acquisto F, Bland EJ, Bombardieri M, Pitzalis C et al.(2014). How the microenvironment contributes to the establishment of chronic inflammatory diseases: lactate regulates metabolic and pro-inflammatory circuits in control of T cell migration and functions. IMMUNOLOGY vol. 143, 151-151.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6636
Montero-Melendez T, Madeira MFM, Norling LV, Alsam A, Curtis MA, da Silva TA, Perretti M(2014). Association between periodontal disease and inflammatory arthritis reveals modulatory functions by melanocortin receptor type 3. Am J Pathol vol. 184, (8) 2333-2341.
10.1016/j.ajpath.2014.04.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43046
Montero-Melendez T, Perretti M(2014). Gapdh gene expression is modulated by inflammatory arthritis and is not suitable for qPCR normalization. Inflammation vol. 37, (4) 1059-1069.
10.1007/s10753-014-9829-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43007
Montero-Melendez T, Perretti M(2014). Connections in pharmacology: innovation serving translational medicine. Drug Discov Today vol. 19, (7) 820-823.
10.1016/j.drudis.2013.11.022
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43063
Dalli J, Norling LV, Montero-Melendez T, Federici Canova D, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al.(2014). Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis. EMBO Mol Med vol. 6, (1) 27-42.
10.1002/emmm.201303503
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10756
Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ, Perretti M(2013). Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A vol. 110, (45) 18232-18237.
10.1073/pnas.1308253110
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11983
Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M(2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Mol Cell Proteomics vol. 12, (8) 2205-2219.
10.1074/mcp.M113.028589
Montero-Melendez T, Dalli J, Perretti M(2013). Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors. Cell Death Differ vol. 20, (4) 567-575.
10.1038/cdd.2012.154
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19645
Perretti M, Dalli J, Norling LV, Montero-Melendez T, Hinds C (2013). Neutrophil Microparticles are heterogenous in content and function. FASEB JOURNAL. vol. 27,
10.1096/fasebj.27.1_supplement.138.5
Calleja MA, Vieites JM, Montero-Meléndez T, Torres MI, Faus MJ, Gil A, Suárez A(2013). The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation. Br J Nutr vol. 109, (3) 394-401.
10.1017/S0007114512001298
Rhodes DH, Pini M, Castellanos KJ, Montero-Melendez T, Cooper D, Perretti M, Fantuzzi G(2013). Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function. Obesity (Silver Spring) vol. 21, (2) 310-319.
10.1002/oby.20016
Schutters K, Kusters DHM, Chatrou MLL, Montero-Melendez T, Donners M, Deckers NM, Krysko DV, Vandenabeele P et al.(2013). Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells. Cell Death Differ vol. 20, (1) 49-56.
10.1038/cdd.2012.107
Ahmed TJ, Montero-Melendez T, Perretti M, Pitzalis C(2013). Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides. Int J Inflam vol. 2013,
10.1155/2013/985815
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32370
Montero-Meléndez T, Llor X, García-Planella E, Perretti M, Suárez A(2013). Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling. PLoS One vol. 8, (10)
10.1371/journal.pone.0076235
Al-Kashi A, Montero-Melendez T, Moradi-Bidhendi N, Gilligan JP, Mehta N, Perretti M(2013). The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis. PLoS One vol. 8, (2)
10.1371/journal.pone.0054299
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5205
de Lima CB, Tamura EK, Montero-Melendez T, Palermo-Neto J, Perretti M, Markus RP, Farsky SHP(2012). Actions of translocator protein ligands on neutrophil adhesion and motility induced by G-protein coupled receptor signaling. Biochem Biophys Res Commun vol. 417, (2) 918-923.
10.1016/j.bbrc.2011.12.078
Dalli J, Montero-Melendez T, McArthur S, Perretti M(2012). Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol vol. 3,
10.3389/fphar.2012.00028
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18353
Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed M, Perretti M, Chernajovsky Y(2012). Molecular engineering of short half-life small peptides (VIP, αMSH and γ₃MSH) fused to latency-associated peptide results in improved anti-inflammatory therapeutics. Ann Rheum Dis vol. 71, (1) 143-149.
10.1136/annrheumdis-2011-200100
Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Frontiers in Immunology vol. 2, Article 41, 1-6.
10.3389/fimmu.2011.00041
https://qmro.qmul.ac.uk/xmlui/handle/123456789/29119
Montero-Melendez T, Patel HB, Seed M, Nielsen S, Jonassen TEN, Perretti M(2011). The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties. Am J Pathol vol. 179, (1) 259-269.
10.1016/j.ajpath.2011.03.042
Rhodes D, Pini M, Montero-Melendez T, Perretti M, Fantuzzi G (2011). EXPRESSION OF ANNEXIN A1 IN ADIPOSE TISSUE IS DISSOCIATED FROM MACROPHAGE INFILTRATION DURING DEVELOPMENT OF OBESITY IN MICE. INFLAMMATION RESEARCH. vol. 60, 261-261.
Montero-Melendez T, Jonassen T, Seed M, Perretti M (2011). MC3 AGONISTS AS NOVEL PRO-RESOLVING THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 269-269.
Greco KV, Montero-Melendez T, Patel H, Perretti M (2011). MELANOCORTIN RECEPTOR AGONISTS ARE NOVEL CHONDROPROTECTIVE THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 273-273.
Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed MP, Perretti M, Chernajovsky Y (2011). MOLECULAR ENGINEERING OF SHORT HALF LIFE SMALL PEPTIDES (VIP, alpha MSH AND gamma 3MSH) INTO LATENT ASSOCIATED PEPTIDE (LAP) RESULTS IN TARGETED ANTI-INFLAMMATORY AND ANTI-RHEUMATIC THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 43-43.
Montero-Melendez T, Patel HB, Perretti M(2011). Role of melanocortin receptors in the regulation of gouty inflammation. Curr Rheumatol Rep vol. 13, (2) 138-145.
10.1007/s11926-011-0163-0
Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Front Immunol vol. 2,
10.3389/fimmu.2011.00041
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25546
Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M(2010). Downstream gene activation of the receptor ALX by the agonist annexin A1. PLoS One vol. 5, (9)
10.1371/journal.pone.0012771
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10712
Suarez Garcia A, MONTERO MELENDEZ T(2010). Tratado de Nutrición. 2a ed. Tomo I: Bases Fisiológicas y Bioquímicas de la Nutrición.(Encuadernación: Rústica). Tratado de Nutrición. 2a ed. Tomo I: Bases Fisiológicas y Bioquímicas de la Nutrición.(Encuadernación: Rústica), Editors: Hernandez, AG, Ed. Médica Panamericana
Patel HB, Leoni G, MONTERO MELENDEZ T, Sampaio A, Perretti M(2010). Melanocortins. Melanocortins, Editors: Catania, A, Springer Verlag
Patel HB, Leoni G, Montero-Melendez T, Sampaio AL, Perretti M(2010). Melanocortin control of cell trafficking in vascular inflammation. Melanocortins: Multiple Actions and Therapeutic Potential. Advances in Experimental Medicine and Biology, vol 681, Editors: ?, vol. 681,
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43049
Gila A, Aguilera CM, Tofe I, Suarez A, Montero T, Gil-Campos M, Canete R (2008). Altered gene expresión associated with lipid metabolism in adipose tissue of obese children. Obesity Reviews. Editors: ?, Conference: 18th Annual Meeting of the European Childhood Obesity Group (Porto (Portugal)) from: 05/06/2008 to: 07/06/2008, vol. 9, Suppl.2, 17-18.
Montero T, Llor X, Suarez A (2008). Gene-expression signature-based approach identifies pro-apoptotic compounds in Caco-2 cell line. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2008 (San Diego (USA)) vol. 4, Suppl.1,
Gil A, Aguilera CM, Montero T, Suarez A, Tofe I, Gil-Campos M, Canete R (2007). Altered Gene Expression Associated with Inflammation in Adipose Tissue of Obese Children. International Journal of Obesity. Editors: ?, Conference: 17th Annual Meeting of the European Chilhood Obesity Group (ECOG) (Athens (Greece))
Montero T, Vieites JM, Llor X, Martinez O, Sanchez de Medina F, Gil A, Gassull MA, Suarez A (2007). Comparative genomic analysis of rat IBD models identifies new genes and biological processes as potential therapeutic targets. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2007 (Washington D.C. (USA)) vol. 4, Suppl.1,
Montero T, Vieites JM, Sanchez de Medina F, Llor X, Martinez O, Gassull MA, Suarez A (2007). Genomic expression analysis reveals new molecular and cellular events involved in the pathogenesis of DSS-induced colitis. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2007 (Washington D.C. (USA)) vol. 4, Suppl.1,
Montero T, Vieites JM, Llor X, Marinez O, Sanchez de Medina F, Suarez A (2006). A comparative genomic perspective on murine inflammatory bowel disease models. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2006 (Los Angeles (USA)) vol. 4, Suppl.2,
Montero T, Vieites JM, Llor X, Marinez O, Sanchez de Medina F, Suarez A (2006). Análisis genómico comparativo de varios modelos animales de Enfermedad Inflamatoria Intestinal. Editors: ?, Conference: Digestive Diseases Week: LXV Congress of the Spanish Society of Digestive Pathology (Granada (Spain)) vol. 98, Suppl.1,
Montero T, Aguilera CM, Suarez A, Gomez-Llorente C, Tofe I, Gomez E, Gil M, Canete R et al. (2006). Changes in the Expression of Genes Related to Insulin Signaling in Adipose Tissue of Obese Children. International Journal of Obesity. Editors: ?, Conference: 16th Annual Meeting of the European Chilhood Obesity Group (ECOG) (Rzeszów (Poland)) vol. 30, Suppl.2S, S1-S43.
Montero T, Martinez O, Vieites JM, Llor X, Gassull MA, Suarez MD, Zarzuelo A, Suarez A et al. (2006). Efectos de la sulfasalazina en el perfil de expresión génica de la colitis inducida por ácido trinitrobencenosulfónico en ratas. Spanish Journal of Digestive Diseases. Editors: ?, Conference: Digestive Diseases Week: LXV Congress of the Spanish Society of Digestive Pathology (Granada (Spain)) vol. 98, Suppl.1,
Martinez O, Montero T, Suarez A, Llor X, Vieites JM, Suarez MD, Zarzuelo A, Sanchez de Medina F (2006). Effect of sulfasalazine on the colonic transcriptome in rat TNBS colitis. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2007 (Washington D.C. (USA)) vol. 4, Suppl.1,
Vieites JM, de la Torre R, Ortega MA, Montero-Melendez T, Peco JM, Sanchez-Pozo A, Gil A, Suarez A(2003). Characterization of human cd200 glycoprotein receptor gene located on chromosome 3q12-13. Gene vol. 311, 99-104.
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