Publications:  Dr Trinidad Montero Melendez

Montero Melendez T, Nagano A, Chelala C, Filer A, Buckley CD, Perretti M(2020). Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis. Nature Communications vol. 11, (1) Article 745,

MONTERO MELENDEZ T(2018). MAY INFLAMMATION BE WITH YOU!. Frontiers For Young Minds

Patruno S, Garrido-Mesa J, Romano M, PERRETTI M, MONTERO MELENDEZ T(2018). Ligand bias and its association with pro-resolving actions of melanocortin drugs. Frontiers in Pharmacology vol. 9, (919)

Perretti M, Montero-Melendez T(2017). Resolution in an 'over-inflamed' era. Biochemist vol. 39, (4) 4-7.

Kaneva MK, Greco KV, Headland SE, Montero-Melendez T, Mori P, Greenslade K, Pitzalis C, Moore A et al.(2017). Identification of novel chondroprotective mediators in resolving inflammatory exudates. Journal of Immunology vol. 198, (7) 2876-2885.

Montero-Melendez T, Forfar RAE, Cook JM, Jerman JC, Taylor DL, Perretti M(2017). Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3. Cellular and Molecular Life Sciences vol. 74, (7) 1335-1345.

Simeoli R, Mattace Raso G, Pirozzi C, Lama A, Santoro A, Russo R, Montero-Melendez T, Berni Canani R et al.(2017). An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis. British Journal of Pharmacology vol. 174, (11) 1484-1496.

Madeira MFM, Queiroz-Junior CM, Montero-Melendez T, Werneck SMC, Correa JD, Soriani FM, Garlet GP, Souza DG et al.(2016). Melanocortin agonism as a viable strategy to control alveolar bone loss induced by oral infection. The FASEB Journal

MONTERO MELENDEZ T, Buckley CD, Filer A, Turner JD, Perretti M (2016). TARGETING SYNOVIAL FIBROBLASTS WITH MELANOCORTIN DRUGS. ANNALS OF THE RHEUMATIC DISEASES. Conference: Annual European Congress of Rheumatology EULAR 2016 vol. 75, 923-923.

Perretti M, Leroy X, Bland EJ, Montero-Melendez T(2015). Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation. Trends in Pharmacological Sciences vol. 36, (11) 737-755.

Montero-Melendez T(2015). ACTH: The forgotten therapy. Semin Immunol vol. 27, (3) 216-226.

Montero-Melendez T, Gobbetti T, Cooray SN, Jonassen TE, Perretti M(2015). Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol vol. 194, (7) 3381-3388.

Haas R, Smith J, Rocher-Ros V, Nadkarni S, Montero-Melendez T, D¿Acquisto F, Bland EJ, Bombardieri M et al.(2015). Lactate regulates metabolic and proinflammatory circuits in control of T cell migration and effector functions. PLoS Biology vol. 13, (7)

Haas R, Smith J, Rocher-Ros V, Montero-Melendez T, D'Acquisto F, Bland EJ, Bombardieri M, Pitzalis C et al.(2014). How the microenvironment contributes to the establishment of chronic inflammatory diseases: lactate regulates metabolic and pro-inflammatory circuits in control of T cell migration and functions. IMMUNOLOGY vol. 143, 151-151.

Montero-Melendez T, Madeira MFM, Norling LV, Alsam A, Curtis MA, da Silva TA, Perretti M(2014). Association between periodontal disease and inflammatory arthritis reveals modulatory functions by melanocortin receptor type 3. Am J Pathol vol. 184, (8) 2333-2341.

Montero-Melendez T, Perretti M(2014). Gapdh gene expression is modulated by inflammatory arthritis and is not suitable for qPCR normalization. Inflammation vol. 37, (4) 1059-1069.

Montero-Melendez T, Perretti M(2014). Connections in pharmacology: innovation serving translational medicine. Drug Discov Today vol. 19, (7) 820-823.

Dalli J, Norling LV, Montero-Melendez T, Federici Canova D, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al.(2014). Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis. EMBO Mol Med vol. 6, (1) 27-42.

Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ, Perretti M(2013). Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A vol. 110, (45) 18232-18237.

Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M(2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Mol Cell Proteomics vol. 12, (8) 2205-2219.

Montero-Melendez T, Dalli J, Perretti M(2013). Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors. Cell Death Differ vol. 20, (4) 567-575.

Perretti M, Dalli J, Norling LV, Montero-Melendez T, Hinds C (2013). Neutrophil Microparticles are heterogenous in content and function. FASEB JOURNAL. vol. 27,

Calleja MA, Vieites JM, Montero-Meléndez T, Torres MI, Faus MJ, Gil A, Suárez A(2013). The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation. Br J Nutr vol. 109, (3) 394-401.

Rhodes DH, Pini M, Castellanos KJ, Montero-Melendez T, Cooper D, Perretti M, Fantuzzi G(2013). Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function. Obesity (Silver Spring) vol. 21, (2) 310-319.

Schutters K, Kusters DHM, Chatrou MLL, Montero-Melendez T, Donners M, Deckers NM, Krysko DV, Vandenabeele P et al.(2013). Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells. Cell Death Differ vol. 20, (1) 49-56.

Ahmed TJ, Montero-Melendez T, Perretti M, Pitzalis C(2013). Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides. Int J Inflam vol. 2013,

Montero-Meléndez T, Llor X, García-Planella E, Perretti M, Suárez A(2013). Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling. PLoS One vol. 8, (10)

Al-Kashi A, Montero-Melendez T, Moradi-Bidhendi N, Gilligan JP, Mehta N, Perretti M(2013). The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis. PLoS One vol. 8, (2)

de Lima CB, Tamura EK, Montero-Melendez T, Palermo-Neto J, Perretti M, Markus RP, Farsky SHP(2012). Actions of translocator protein ligands on neutrophil adhesion and motility induced by G-protein coupled receptor signaling. Biochem Biophys Res Commun vol. 417, (2) 918-923.

Dalli J, Montero-Melendez T, McArthur S, Perretti M(2012). Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol vol. 3,

Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed M, Perretti M, Chernajovsky Y(2012). Molecular engineering of short half-life small peptides (VIP, αMSH and γ₃MSH) fused to latency-associated peptide results in improved anti-inflammatory therapeutics. Ann Rheum Dis vol. 71, (1) 143-149.

Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Frontiers in Immunology vol. 2, Article 41, 1-6.

Montero-Melendez T, Patel HB, Seed M, Nielsen S, Jonassen TEN, Perretti M(2011). The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties. Am J Pathol vol. 179, (1) 259-269.

Rhodes D, Pini M, Montero-Melendez T, Perretti M, Fantuzzi G (2011). EXPRESSION OF ANNEXIN A1 IN ADIPOSE TISSUE IS DISSOCIATED FROM MACROPHAGE INFILTRATION DURING DEVELOPMENT OF OBESITY IN MICE. INFLAMMATION RESEARCH. vol. 60, 261-261.

Montero-Melendez T, Jonassen T, Seed M, Perretti M (2011). MC3 AGONISTS AS NOVEL PRO-RESOLVING THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 269-269.

Greco KV, Montero-Melendez T, Patel H, Perretti M (2011). MELANOCORTIN RECEPTOR AGONISTS ARE NOVEL CHONDROPROTECTIVE THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 273-273.

Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed MP, Perretti M, Chernajovsky Y (2011). MOLECULAR ENGINEERING OF SHORT HALF LIFE SMALL PEPTIDES (VIP, alpha MSH AND gamma 3MSH) INTO LATENT ASSOCIATED PEPTIDE (LAP) RESULTS IN TARGETED ANTI-INFLAMMATORY AND ANTI-RHEUMATIC THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 43-43.

Montero-Melendez T, Patel HB, Perretti M(2011). Role of melanocortin receptors in the regulation of gouty inflammation. Curr Rheumatol Rep vol. 13, (2) 138-145.

Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Front Immunol vol. 2,

Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M(2010). Downstream gene activation of the receptor ALX by the agonist annexin A1. PLoS One vol. 5, (9)

Suarez Garcia A, MONTERO MELENDEZ T(2010). Tratado de Nutrición. 2a ed. Tomo I: Bases Fisiológicas y Bioquímicas de la Nutrición.(Encuadernación: Rústica). Tratado de Nutrición. 2a ed. Tomo I: Bases Fisiológicas y Bioquímicas de la Nutrición.(Encuadernación: Rústica), Editors: Hernandez, AG, Ed. Médica Panamericana

Patel HB, Leoni G, MONTERO MELENDEZ T, Sampaio A, Perretti M(2010). Melanocortins. Melanocortins, Editors: Catania, A, Springer Verlag

Patel HB, Leoni G, Montero-Melendez T, Sampaio AL, Perretti M(2010). Melanocortin control of cell trafficking in vascular inflammation. Melanocortins: Multiple Actions and Therapeutic Potential. Advances in Experimental Medicine and Biology, vol 681, Editors: ?, vol. 681,

Gila A, Aguilera CM, Tofe I, Suarez A, Montero T, Gil-Campos M, Canete R (2008). Altered gene expresión associated with lipid metabolism in adipose tissue of obese children. Obesity Reviews. Editors: ?, Conference: 18th Annual Meeting of the European Childhood Obesity Group (Porto (Portugal)) from: 05/06/2008 to: 07/06/2008, vol. 9, Suppl.2, 17-18.

Montero T, Llor X, Suarez A (2008). Gene-expression signature-based approach identifies pro-apoptotic compounds in Caco-2 cell line. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2008 (San Diego (USA)) vol. 4, Suppl.1,

Gil A, Aguilera CM, Montero T, Suarez A, Tofe I, Gil-Campos M, Canete R (2007). Altered Gene Expression Associated with Inflammation in Adipose Tissue of Obese Children. International Journal of Obesity. Editors: ?, Conference: 17th Annual Meeting of the European Chilhood Obesity Group (ECOG) (Athens (Greece))

Montero T, Vieites JM, Llor X, Martinez O, Sanchez de Medina F, Gil A, Gassull MA, Suarez A (2007). Comparative genomic analysis of rat IBD models identifies new genes and biological processes as potential therapeutic targets. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2007 (Washington D.C. (USA)) vol. 4, Suppl.1,

Montero T, Vieites JM, Sanchez de Medina F, Llor X, Martinez O, Gassull MA, Suarez A (2007). Genomic expression analysis reveals new molecular and cellular events involved in the pathogenesis of DSS-induced colitis. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2007 (Washington D.C. (USA)) vol. 4, Suppl.1,

Montero T, Vieites JM, Llor X, Marinez O, Sanchez de Medina F, Suarez A (2006). A comparative genomic perspective on murine inflammatory bowel disease models. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2006 (Los Angeles (USA)) vol. 4, Suppl.2,

Montero T, Vieites JM, Llor X, Marinez O, Sanchez de Medina F, Suarez A (2006). Análisis genómico comparativo de varios modelos animales de Enfermedad Inflamatoria Intestinal. Editors: ?, Conference: Digestive Diseases Week: LXV Congress of the Spanish Society of Digestive Pathology (Granada (Spain)) vol. 98, Suppl.1,

Montero T, Aguilera CM, Suarez A, Gomez-Llorente C, Tofe I, Gomez E, Gil M, Canete R et al. (2006). Changes in the Expression of Genes Related to Insulin Signaling in Adipose Tissue of Obese Children. International Journal of Obesity. Editors: ?, Conference: 16th Annual Meeting of the European Chilhood Obesity Group (ECOG) (Rzeszów (Poland)) vol. 30, Suppl.2S, S1-S43.

Montero T, Martinez O, Vieites JM, Llor X, Gassull MA, Suarez MD, Zarzuelo A, Suarez A et al. (2006). Efectos de la sulfasalazina en el perfil de expresión génica de la colitis inducida por ácido trinitrobencenosulfónico en ratas. Spanish Journal of Digestive Diseases. Editors: ?, Conference: Digestive Diseases Week: LXV Congress of the Spanish Society of Digestive Pathology (Granada (Spain)) vol. 98, Suppl.1,

Martinez O, Montero T, Suarez A, Llor X, Vieites JM, Suarez MD, Zarzuelo A, Sanchez de Medina F (2006). Effect of sulfasalazine on the colonic transcriptome in rat TNBS colitis. Gastroenterology. Editors: ?, Conference: Digestive Diseases Week 2007 (Washington D.C. (USA)) vol. 4, Suppl.1,

Vieites JM, de la Torre R, Ortega MA, Montero-Melendez T, Peco JM, Sanchez-Pozo A, Gil A, Suarez A(2003). Characterization of human cd200 glycoprotein receptor gene located on chromosome 3q12-13. Gene vol. 311, 99-104.