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Publications:  Mr Charles Mein

Crescente M, Armstrong PC, Kirkby NS, Edin ML, Chan MV, Lih FB, Jiao J, Maffucci T et al.(2020). Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin. The FASEB Journal
10.1096/fj.202000312R
Lone NM, Riaz S, Eusaph AZ, Mein CA, Wozniak EL, Xenakis T, Wu Z, Younis S et al.(2020). Genotype-independent association between vitamin D deficiency and polycystic ovarian syndrome in Lahore, Pakistan. Scientific Reports vol. 10, (1)
10.1038/s41598-020-59228-4
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63084
Thomas AM, Cabrera CP, Finlay M, Lall K, Nobles M, Schilling RJ, Wood K, Mein CA et al.(2019). Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages. Physiol Genomics vol. 51, (8) 323-332.
10.1152/physiolgenomics.00012.2019
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59231
Biserni M, Mesnage R, Ferro R, Wozniak E, Xenakis T, Mein CA, Antoniou MN(2019). Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes. Toxicological Sciences vol. 170, (2) 452-461.
10.1093/toxsci/kfz097
Carbajosa G, Malki K, Lawless N, Wang H, Ryder JW, Wozniak E, Wood K, Mein CA et al.(2018). Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain. Neurobiology of Aging vol. 69, 151-166.
10.1016/j.neurobiolaging.2018.04.019
Jolliffe DA, Greiller CL, Mein CA, Hoti M, Bakhsoliani E, Telcian AG, Simpson A, Barnes NC et al.(2018). Vitamin D receptor genotype influences risk of upper respiratory infection. Br J Nutr1-10.
10.1017/S000711451800209X
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44483
Mesnage R, Biserni M, Balu S, Frainay C, Poupin N, Jourdan F, Wozniak E, Xenakis T et al.(2018). Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126. Archives of Toxicology vol. 92, (8) 2533-2547.
10.1007/s00204-018-2235-7
Soulsbury CD, Lipponen A, Wood K, Mein CA, Hoffman JI, Lebigre C(2018). Age- and quality-dependent DNA methylation correlate with melanin-based coloration in a wild bird. Ecology and Evolution vol. 8, (13) 6547-6557.
10.1002/ece3.4132
KELSELL DP, O'TOOLE E, PIGORS M, SCOTT CA, Tabarra N, VAN HEEL DA(2018). Exome sequencing and rare variant analysis reveals multiple filaggrin mutations in Bangladeshi atopic eczema families and novel risk genes. Journal of Investigative Dermatology
10.1016/j.jid.2018.05.013
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39403
Gilbert RM, Zhang X, Sampson RD, Ehrenstein MR, Nguyen DX, Chaudhry M, Mein C, Mahmud N et al.(2018). Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT. Frontiers in Immunology vol. 9, 907-907.
10.3389/fimmu.2018.00907
Mesnage R, Biserni M, Wozniak E, Xenakis T, Mein CA, Antoniou MN(2018). Comparison of transcriptome responses to glyphosate, isoxaflutole, quizalofop-p-ethyl and mesotrione in the HepaRG cell line. Toxicology Reports vol. 5, 819-826.
10.1016/j.toxrep.2018.08.005
Seaborne RA, Strauss J, Cocks M, Shepherd S, O¿brien TD, van Someren KA, Bell PG, Murgatroyd C et al.(2018). Methylome of human skeletal muscle after acute & chronic resistance exercise training, detraining & retraining. Scientific Data vol. 5,
10.1038/sdata.2018.213
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50163
Munroe PB, Addison S, Abrams DJ, Sebire NJ, Cartwright J, Donaldson I, Cohen MM, Mein C et al.(2018). Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths. Circulation. Genomic and precision medicine vol. 11, (1)
10.1161/CIRCGEN.117.001817
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45703
Clark LV, Buckland M, Murphy G, Taylor N, Vleck V, Mein C, Wozniak E, Smuk M et al.(2017). Cytokine responses to exercise and activity in patients with chronic fatigue syndrome: case–control study. Clinical and Experimental Immunology vol. 190, (3) 360-371.
10.1111/cei.13023
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49349
Das A, Rouault-Pierre K, Kamdar S, Gomez-Tourino I, Wood K, Donaldson I, Mein CA, Bonnet D et al.(2017). Adaptive from Innate: Human IFN-γ+CD4+T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults. J Immunol vol. 199, (5) 1696-1705.
10.4049/jimmunol.1700551
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34783
Turner RD, Bourne E, Mein CA, Birring SS, Shaheen SO, Bothamley GH (2016). TRPV1 POLYMORPHISM IN CHRONIC COUGH: NO EVIDENCE FOR AN EFFECT ON OBJECTIVE MEASUREMENTS OF COUGH. THORAX. vol. 71, A263-A264.
10.1136/thoraxjnl-2016-209333.454
Kitchen MO, Bryan RT, Emes RD, Glossop JR, Luscombe C, Cheng KK, Zeegers MP, James ND et al.(2016). Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer. Epigenetics vol. 11, (3) 237-246.
10.1080/15592294.2016.1154246
Kokkinopoulos I, Ishida H, Saba R, Ruchaya P, Cabrera C, Struebig M, Barnes M, Terry A et al.(2015). Single-cell expression profiling reveals a dynamic state of cardiac precursor cells in the early mouse embryo. PLoS ONE vol. 10, (10)
10.1371/journal.pone.0140831
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13417
Martineau AR, MacLaughlin BD, Hooper RL, Barnes NC, Jolliffe DA, Greiller CL, Kilpin K, McLaughlin D et al.(2015). Double-blind randomised placebo-controlled trial of bolus-dose vitamin D<inf>3</inf> supplementation in adults with asthma (ViDiAs). Thorax vol. 70, (5) 451-457.
10.1136/thoraxjnl-2014-206449
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6998
Bulmer DC, Botha CA, Wheeldon A, Grey K, Mein CA, Lee K, Knowles CH, Winchester WJ et al.(2015). Evidence of a role for GTP cyclohydrolase-1 in visceral pain. Neurogastroenterology and Motility vol. 27, (5) 656-662.
10.1111/nmo.12538
Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ(2015). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Annals of Surgery vol. 261, (4) 751-759.
10.1097/SLA.0000000000000653
Yousaf N, Low WY, Onipinla A, Mein C, Caulfield M, Munroe PB, Chernajovsky Y(2015). Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines. Clinical and Experimental Immunology vol. 180, (2) 289-304.
10.1111/cei.12575
Rautanen A, Mills TC, Gordon AC, Hutton P, Steffens M, Nuamah R, Chiche JD, Parks T et al.(2015). Genome-wide association study of survival from sepsis due to pneumonia: An observational cohort study. The Lancet Respiratory Medicine vol. 3, (1) 53-60.
10.1016/S2213-2600(14)70290-5
Salas-Alanis JC, Wozniak E, Mein CA, Mckinster CCD, Ocampo-Candiani J, Kelsell DP, Hua R, Garza-Rodriguez ML et al.(2015). Mutations in EDA and EDAR genes in a large mexican hispanic cohort with hypohidrotic ectodermal dysplasia. Annals of Dermatology vol. 27, (4) 474-477.
10.5021/ad.2015.27.4.474
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23230
Jolliffe DA, Martineau AR, Maclaughlin BM, Kiplin KK, Timms PMT, Mein CAM, Walton RW, Griffiths CJG (2014). PREVALENCE AND DETERMINANTS OF VITAMIN D DEFICIENCY IN ASTHMA PATIENTS. THORAX. vol. 69, A94-A95.
10.1136/thoraxjnl-2014-206260.189
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9501
Jolliffe DA, Martineau AR, James WYJ, Islam KI, Mein CAM, Timms PMT, Walton RW, Griffiths CJG (2014). PREVALENCE AND DETERMINANTS OF VITAMIN D DEFICIENCY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. THORAX. vol. 69, A215-A216.
10.1136/thoraxjnl-2014-206260.440
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9500
Torrance HDT, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ (2014). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. vol. 22,
10.1186/1757-7241-22-S1-O7
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12107
Torrance HDT, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ(2014). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Annals of Surgery
10.1097/SLA.0000000000000653
Riebler A, Menigatti M, Song JZ, Statham AL, Stirzaker C, Mahmud N, Mein CA, Clark SJ et al.(2014). BayMeth:Improved DNA methylation quantification for affinity capture sequencing data using a flexible Bayesian approach. Genome Biology vol. 15, (2)
10.1186/gb-2014-15-2-r35
Okosun J, Bödör C, Wang J, Araf S, Yang CY, Pan C, Boller S, Cittaro D et al.(2014). Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics vol. 46, (2) 176-181.
10.1038/ng.2856
Torrance HDT, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O¿Dwyer MJ(2014). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Scandinavian journal of trauma, resuscitation and emergency medicine vol. 22, (Suppl 1) O7-O7.
10.1186/1757-7241-22-s1-o7
Pryce G, Visintin C, Ramagopalan SV, Al-Izki S, De Faveri LE, Nuamah RA, Mein CA, Montpetit A et al.(2014). Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB<inf>1</inf> cannabinoid receptor agonists. FASEB Journal vol. 28, (1) 117-130.
10.1096/fj.13-239442
Haworth KE, Farrell WE, Emes RD, Ismail KMK, Carroll WD, Hubball E, Rooney A, Yates AM et al.(2014). Methylation of the FGFR2 gene is associated with high birth weight centile in humans. Epigenomics vol. 6, (5) 477-491.
10.2217/epi.14.40
Hill MJ, Donocik JG, Nuamah RA, Mein CA, Sainz-Fuertes R, Bray NJ(2014). Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells. Schizophrenia Research vol. 153, (1-3) 225-230.
10.1016/j.schres.2014.01.034
Coussens AK, Wilkinson RJ, Nikolayevskyy V, Elkington PT, Hanifa Y, Islam K, Timms PM, Bothamley GH et al. (2013). Ethnic Variation in Inflammatory Profile in Tuberculosis. PLoS Pathogens. vol. 9,
10.1371/journal.ppat.1003468
Carter JA, Górecki DC, Mein CA, Ljungberg B, Hafizi S(2013). CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma. Epigenetics vol. 8, (7) 739-747.
10.4161/epi.25075
Coussens AK, Wilkinson RJ, Nikolayevskyy V, Elkington PT, Hanifa Y, Islam K, Timms PM, Bothamley GH et al.(2013). Ethnic variation in inflammatory profile in tuberculosis. PLoS Pathog vol. 9, (7)
10.1371/journal.ppat.1003468
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5200
Okosun J, Bödör C, Wang J, Araf S, Yang C-Y, Pan C, Boller S, Cittaro D et al.(2013). Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics
10.1038/ng.2856
Hunt KA, Mistry V, Bockett NA, Ahmad T, Ban M, Barker JN, Barrett JC, Blackburn H et al.(2013). Negligible impact of rare autoimmune-locus coding-region variants on missing heritability. Nature vol. 498, (7453) 232-235.
10.1038/nature12170
Addison S, Sebire NJ, Taylor AM, Abrams D, Peebles D, Mein C, Munroe PB, Thayyil S(2012). High quality genomic DNA extraction from postmortem fetal tissue. Journal of Maternal-Fetal and Neonatal Medicine vol. 25, (11) 2467-2469.
10.3109/14767058.2012.704442
Brouilette S, Kuersten S, Mein C, Bozek M, Terry A, Dias KR, Bhaw-Rosun L, Shintani Y et al.(2012). A simple and novel method for RNA-seq library preparation of single cell cDNA analysis by hyperactive Tn5 transposase. Developmental Dynamics vol. 241, (10) 1584-1590.
10.1002/dvdy.23850
Coussens AK, Wilkinson RJ, Hanifa Y, Nikolayevskyy V, Elkington PT, Islam K, Timms PM, Venton TR et al.(2012). Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment. Proceedings of the National Academy of Sciences of the United States of America vol. 109, (38) 15449-15454.
10.1073/pnas.1200072109
Wright WR, Parzych K, Crawford D, Mein C, Mitchell JA, Paul-Clark MJ(2012). Inflammatory transcriptome profiling of human monocytes exposed acutely to Cigarette smoke. PLoS ONE vol. 7, (2)
10.1371/journal.pone.0030120
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28592
Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC et al.(2012). Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nature Genetics vol. 44, (1) 3-5.
10.1038/ng.1037
Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I et al.(2011). Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics vol. 89, (6) 688-700.
10.1016/j.ajhg.2011.10.013
Trynka G, Hunt KA, Bockett NA, Romanos J, Mistry V, Szperl A, Bakker SF, Bardella MT et al.(2011). Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nature Genetics vol. 43, (12) 1193-1201.
10.1038/ng.998
Pathan N, Burmester M, Adamovic T, Berk M, Ng KW, Betts H, Macrae D, Waddell S et al.(2011). Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease. American Journal of Respiratory and Critical Care Medicine vol. 184, (11) 1261-1269.
10.1164/rccm.201104-0715OC
Rakyan VK, Beyan H, Down TA, Hawa MI, Maslau S, Aden D, Daunay A, Busato F et al. (2011). Identification of type 1 Diabetes-associated DNA methylation variable positions that precede disease diagnosis. PLoS Genetics. vol. 7,
10.1371/journal.pgen.1002300
Rakyan VK, Beyan H, Down TA, Hawa MI, Maslau S, Aden D, Daunay A, Busato F et al.(2011). Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis. PLoS Genet vol. 7, (9)
10.1371/journal.pgen.1002300
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5415
Rajpopat S, Moss C, Mellerio J, Vahlquist A, Gånemo A, Hellstrom-Pigg M, Ilchyshyn A, Burrows N et al.(2011). Harlequin ichthyosis: A review of clinical and molecular findings in 45 cases. Archives of Dermatology vol. 147, (6) 681-686.
10.1001/archdermatol.2011.9
Watt SA, Pourreyron C, Purdie K, Hogan C, Cole CL, Foster N, Pratt N, Bourdon J-C et al.(2011). Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma. Oncogene vol. 30, (46) 4666-4677.
10.1038/onc.2011.180
Husain EA, Mein C, Pozo L, Blanes A, Diaz-Cano SJ(2011). Heterogeneous topographic profiles of kinetic and cell cycle regulator microsatellites in atypical (dysplastic) melanocytic nevi. Modern Pathology vol. 24, (4) 471-486.
10.1038/modpathol.2010.143
Martineau AR, Timms PM, Bothamley GH, Hanifa Y, Islam K, Claxton AP, Packe GE, Moore-Gillon JC et al.(2011). High-dose vitamin D<inf>3</inf> during intensive-phase antimicrobial treatment of pulmonary tuberculosis: A double-blind randomised controlled trial. The Lancet vol. 377, (9761) 242-250.
10.1016/S0140-6736(10)61889-2
Fryer AA, Emes RD, Ismail KMK, Haworth KE, Mein C, Carroll WD, Farrell WE(2011). Quantitative, high-resolution epigenetic profling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans. Epigenetics vol. 6, (1) 86-94.
10.4161/epi.6.1.13392
Cabral RM, Liu L, Hogan C, Dopping-Hepenstal PJC, Winik BC, Asial RA, Dobson R, Mein CA et al.(2010). Homozygous mutations in the 5′ region of the JUP gene result in cutaneous disease but normal heart development in children. Journal of Investigative Dermatology vol. 130, (6) 1543-1550.
10.1038/jid.2010.7
Maeda E, Fleischmann C, Mein CA, Shelton JC, Bader DL, Lee DA(2010). Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain. Connective Tissue Research vol. 51, (6) 434-444.
10.3109/03008201003597056
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GAR et al.(2010). Erratum: Multiple common variants for celiac disease influencing immune gene expression (Nature Genetics DOI: 10.1038/ng.543). Nature Genetics vol. 42, (5)
10.1038/ng0510-465
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GAR et al.(2010). Multiple common variants for celiac disease influencing immune gene expression (vol 42, pg 295, 2010). NATURE GENETICS vol. 42, (5) 465-465.
10.1038/ng0510-465
Paige AJW, Zucknick M, Janczar S, Paul J, Mein CA, Taylor KJ, Stewart M, Gourley C et al.(2010). WWOX tumour suppressor gene polymorphisms and ovarian cancer pathology and prognosis. European Journal of Cancer vol. 46, (4) 818-825.
10.1016/j.ejca.2009.12.021
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GAR et al.(2010). Multiple common variants for celiac disease influencing immune gene expression. Nature Genetics vol. 42, (4) 295-302.
10.1038/ng.543
Mead S, Whitfield J, Poulter M, Shah P, Uphill J, Campbell T, Al-Dujaily H, Hummerich H et al.(2009). A novel protective prion protein variant that colocalizes with kuru exposure. New England Journal of Medicine vol. 361, (21) 2056-2065.
10.1056/NEJMoa0809716
Heap GA, Yang JHM, Downes K, Healy BC, Hunt KA, Bockett N, Franke L, Dubois PC et al.(2009). Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing. Human Molecular Genetics vol. 19, (1) 122-134.
10.1093/hmg/ddp473
Martins VL, Vyas JJ, Chen M, Purdie K, Mein CA, South AP, Storey A, McGrath JA et al.(2009). Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen. Journal of Cell Science vol. 122, (11) 1788-1799.
10.1242/jcs.042895
Sinclair C, O'Toole EA, Paige D, El Bashir H, Robinson J, Dobson R, Lench N, Stevens HP et al.(2009). Filaggrin mutations are associated with ichthyosis vulgaris in the Bangladeshi population. British Journal of Dermatology vol. 160, (5) 1113-1115.
10.1111/j.1365-2133.2009.09050.x
Iorns E, Lord CJ, Grigoriadis A, McDonald S, Fenwick K, MacKay A, Mein CA, Natrajan R et al.(2009). Integrated functional, gene expression and genomic analysis for the identification of cancer targets. PLoS ONE vol. 4, (4)
10.1371/journal.pone.0005120
Gueorguiev M, Lecoeur C, Meyre D, Benzinou M, Mein CA, Hinney A, Vatin V, Weill J et al.(2009). Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity. Obesity vol. 17, (4) 745-754.
10.1038/oby.2008.589
Gueorguiev M, Lecoeur C, Benzinou M, Mein CA, Meyre D, Vatin V, Weill J, Heude B et al.(2009). A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature. Annals of Human Genetics vol. 73, (1) 1-9.
10.1111/j.1469-1809.2008.00484.x
O'Riain C, O'Shea DM, Yang Y, Le Dieu R, Gribben JG, Summers K, Yeboah-Afari J, Bhaw-Rosun L et al.(2009). Array-based DNA methylation profiling in follicular lymphoma. Leukemia vol. 23, (10) 1858-1866.
10.1038/leu.2009.114
Mead S, Poulter M, Beck J, Uphill J, Jones C, Cheng EA, Mein CA, Collinge J(2008). Successful amplification of degraded DNA for use with high-throughput SNP genotyping platforms. Human Mutation vol. 29, (12) 1452-1458.
10.1002/humu.20782
Yuan M, Tomlinson V, Lara R, Holliday D, Chelala C, Harada T, Gangeswaran R, Manson-Bishop C et al.(2008). Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death and Differentiation vol. 15, (11) 1752-1759.
10.1038/cdd.2008.108
O'Riain C, O'Shea D, Yang Y, Gribben J, Afari J, Mein CA, Crook T, Smith P et al. (2008). Methylation profiling in 158 cases of previously untreated follicular lymphoma (FL). ANNALS OF ONCOLOGY. vol. 19, 101-101.
Dixon-McIver A, East P, Mein CA, Cazier JB, Molloy G, Chaplin T, Lister TA, Young BD et al.(2008). Distinctive patterns of microRNA expression associated with karyotype in acute myeloid leukaemia. PLoS ONE vol. 3, (5)
10.1371/journal.pone.0002141
Zavarella S, Petrone A, Zampetti S, Gueorguiev M, Spoletini M, Mein CA, Leto G, Korbonits M et al.(2008). A new variation in the promoter region, the -604 C&gt;T, and the Leu72Met polymorphism of the ghrelin gene are associated with protection to insulin resistance. International Journal of Obesity vol. 32, (4) 663-668.
10.1038/sj.ijo.0803766
Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC et al.(2008). Newly indentified genetic risk variants for celiac disease related to the immune response. Nat Genet vol. 40, (4) 395-402.
10.1038/ng.102
https://qmro.qmul.ac.uk/xmlui/handle/123456789/3282
Thomas AC, Sinclair C, Mahmud N, Cullup T, Mellerio JE, Harper J, Dale BA, Turc-Carel C et al.(2008). Novel and recurring ABCA12 mutations associated with harlequin ichthyosis: Implications for prenatal diagnosis. British Journal of Dermatology vol. 158, (3) 611-613.
10.1111/j.1365-2133.2007.08277.x
Dobson RJB, Munroe PB, Mein CA, Caulfield MJ, Saqi MAS (2008). Combining protein-protein interaction (PPI) network and sequence attributes for predicting hypertension related proteins. Communications in Computer and Information Science. vol. 13, 377-391.
10.1007/978-3-540-70600-7_28
Dixon-McIver A, East P, Mein CA, Cazier J-B, Molloy G, Chaplin T, Lister TA, Young B et al. (2007). Association of MicroRNA expression profiles with karyotype in acute myeloid leukaemias revealed by real-time PCR and in situ hybridisation. BLOOD. vol. 110, 39A-39A.
10.1182/blood.V110.11.105.105
KORBONITS MJ, Hitman GA, Grossman AB, Gueorguiev M, Mein C, Froguel P, McCarthy MI, Hattersley AT et al.(2007). Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes. J Clin Endocrinol Metab vol. 92, (6) 2201-2204.
10.1210/jc.2006-2657
Sinclair C, O'Toole EA, Paige D, Mein CA, Kelsell DP (2007). A comprehensive survey of 28 candidate genes for atopic dermatitis using a hapTAG approach in a unique Bangladeshi population of East London. BRITISH JOURNAL OF DERMATOLOGY. vol. 156, 1103-1103.
Bell CG, Meyre D, Petretto E, Levy-Marchal C, Hercberg S, Charles MA, Boyle C, Weill J et al.(2007). No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: A model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases. European Journal of Human Genetics vol. 15, (3) 320-327.
10.1038/sj.ejhg.5201754
Arita K, Jacyk WK, Wessagowit V, Van Rensburg EJ, Chaplin T, Mein CA, Akiyama M, Shimizu H et al.(2007). The South African "bathing suit ichthyosis" is a form of lamellar ichthyosis caused by a homozygous missense mutation, p.R315L, in t1ransglutaminase 1 [4]. Journal of Investigative Dermatology vol. 127, (2) 490-493.
10.1038/sj.jid.5700550
Baykal C, Tulunay G, Özfuttu A, Jacobs I, Mein CA, Küçükali T, Ayhan A(2007). Breast and ovarian carcinoma in the same patient, metastasis or dual primaries?. Turkish Journal of Cancer vol. 37, (1) 27-30.
Van Trappen PO, Cullup T, Troke R, Swann D, Shepherd JH, Jacobs IJ, Gayther SA, Mein CA(2007). Somatic mitochondrial DNA mutations in primary and metastatic ovarian cancer. Gynecologic Oncology vol. 104, (1) 129-133.
10.1016/j.ygyno.2006.07.010
KELSELL DP, O'Toole EA, Mein C, Thomas A, Fleckman P, Goodyear H, Wilroy R, DeLozier C et al.(2006). ABCA12 is the major Harlequin Ichthyosis gene. Journal of Investigative Dermatology vol. 126, 2408-2413.
10.1038/sj.jid.5700455
Munroe PB, CAULFIELD MJ, Newhouse SJ, Mein CA, Wallace C, Clayton D, Webster J, Lathrop M et al.(2006). Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British Genetics of Hypertension Study. Hypertension vol. 48, (1) 105-111.
10.1161/01.HYP.0000228324.74255.f1
Munroe PB, CAULFIELD MJ, Wallace C, Newhouse SJ, Clayton DG, Samani NJ, Farrall M, Dominiczak A et al.(2006). Linkage Analysis Using Co-Phenotypes in the BRIGHT Study Reveals Novel Potential Susceptibility Loci for Hypertension. The American Journal of Human Genetics vol. 79, (2) 323-331.
10.1086/506370
Munroe PB, CAULFIELD MJ, Wallace C, Mein C, Pembroke J, Wiltshire D, Dobson R, Bell JT et al.(2006). Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension. Hum Mol Genet vol. 15, (8) 1365-1374.
10.1093/hmg/ddl058
Bell CG, Meyre D, Samson C, Boyle C, Lecoeur C, Tauber M, Jouret B, Jaquet D et al.(2005). Association of melanin-concentrating hormone receptor 1 5′ polymorphism with early-onset extreme obesity. Diabetes vol. 54, (10) 3049-3055.
10.2337/diabetes.54.10.3049
Kelsell DP, Norgett EE, Unsworth H, Teh MT, Cullup T, Mein CA, Dopping-Hepenstal PJ, Kennedy CT et al. (2005). Clinical and molecular features of Harlequin ichthyosis. BRITISH JOURNAL OF DERMATOLOGY. vol. 153, 5-5.
MUNROE PB, Caulfield M, Dobson R, Newhouse SJ, Lathrop GM, Connell JM, Samani N, Clayton D et al.(2005). Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Human Molecular Genetics vol. 14, (13) 1805-1814.
10.1093/hmg/ddi187
KELSELL DP, Leigh IM, O'Toole EA, Mein CA, Norgett EE, Unsworth H, Cullup T, Sybert VP et al.(2005). Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis. Am J Hum Genet vol. 76, 794-803.
10.1086/429844
Roussel Y, Wilks M, Harris A, Mein C, Tabaqchali S(2005). Evaluation of DNA extraction methods from mouse stomachs for the quantification of H. pylori by real-time PCR. Journal of Microbiological Methods vol. 62, (1) 71-81.
10.1016/j.mimet.2005.01.011
Buzzetti R, Petrone A, Caiazzo AM, Alemanno I, Zavarella S, Capizzi M, Mein CA, Osborn JA et al.(2005). PPAR-γ2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity. Pediatric Research vol. 57, (1) 138-140.
10.1203/01.PDR.0000147728.62185.21
MUNROE PB, Caulfield MJ, Mein CA(2005). Selection of candidate genes in hypertension. vol. 108,
Buzzetti R, Petrone A, Ribaudo MC, Alemanno I, Zavarella S, Mein CA, Maiani F, Tiberti C et al.(2004). The common PPAR-γ2 Pro12Ala variant is associated with greater insulin sensitivity. European Journal of Human Genetics vol. 12, (12) 1050-1054.
10.1038/sj.ejhg.5201283
Brinkmann D, Ryan A, Ayhan A, McCluggage WG, Feakins R, Santibanez-Koref MF, Mein CA, Gayther SA et al.(2004). A molecular genetic and statistical approach for the diagnosis of dual-site cancers. Journal of the National Cancer Institute vol. 96, (19) 1441-1446.
10.1093/jnci/djh272
Bell CG, Benzinou M, Siddiq A, Lecoeur C, Dina C, Lemainque A, Clément K, Basdevant A et al.(2004). Genome-wide linkage analysis for severe obesity in French Caucasians finds significant susceptibility locus on chromosome 19q. Diabetes vol. 53, (7) 1857-1865.
10.2337/diabetes.53.7.1857
Mein CA, Caulfield MJ, Dobson RJ, Munroe PB(2004). Genetics of essential hypertension. Human Molecular Genetics vol. 13, (REV. ISS. 1)
MUNROE PB, CAULFIELD MJ, MEIN CA, DOBSON MJ(2004). Genetics of Essential Hypertension. Hum Mol Genet vol. 13 SPEC 1, R169-R175.
10.1093/hmg/ddh078
Froguel P, HITMAN GA, McDermott MF, Mein CA, Allotey RA, Cassell PG, Sinnot PJ, Snehalatha C et al.(2004). The EIF2AK3 gene region and type I diabetes in subjects from South India. Genes Immun vol. 5, 648-652.
10.1038/sj.gene.6364139
Petrone A, Zavarella S, Capizzi M, Baroni M, Galgani A, Fioretti F, Fiori R, Alemanno I et al. (2003). Adiponectin gene is associated with obesity and obesity correlated traits in childhood. DIABETOLOGIA. vol. 46, A137-A137.
Twells RCJ, Mein CA, Payne F, Veijola R, Gilbey M, Bright M, Timms A, Nakagawa Y et al.(2003). Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes. Human Genetics vol. 113, (2) 99-105.
10.1007/s00439-003-0940-6
Beales PL, Badano JL, Ross AJ, Ansley SJ, Hoskins BE, Kirsten B, Mein CA, Froguel P et al.(2003). Genetic interaction of BBS1 mutations with alleles at other BBS loci can result in non-Mendelian Bardet-Biedl syndrome. American Journal of Human Genetics vol. 72, (5) 1187-1199.
10.1086/375178
Twells RCJ, Mein CA, Phillips MS, Hess JF, Veijola R, Gilbey M, Bright M, Metzker M et al.(2003). Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene. Genome Research vol. 13, (5) 845-855.
10.1101/gr.563703
KORBONITS MJ, Grossman AB, Gueorguiev M, Lecoeur C, O'Grady E, Froguel P, Weill J, Swan DC et al.(2002). A Variation in the Ghrelin Gene Increases Weight and Decreases Insulin Secretion in Tall, Obese Children. Journal of Clinical Endocrinology & Metabolism vol. 87, (8) 4005-4008.
10.1210/jc.87.8.4005
Allotey RA, Mohan V, McDermott MF, Deepa R, Premalatha G, Hassan Z, Cassell PG, North BV et al. (2002). Association between E1F2AK3 gene region and Type 1 diabetes in Southern Indian subjects. DIABETOLOGIA. vol. 45, A111-A111.
Mein CA (2001). 'Ome on the range. Trends in Biotechnology. vol. 19, 240-241.
10.1016/S0167-7799(01)01644-4
Mein CA, Barratt BJ, Dunn MG, Siegmund T, Smith AN, Esposito L, Nutland S, Stevens HE et al.(2000). Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation. Genome Research vol. 10, (3) 330-343.
10.1101/gr.10.3.330
Mein CA, Esposito L, Dunn MG, Johnson GCL, Timms AE, Goy JV, Smith AN, Sebag-Montefiore L et al.(1998). A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nature Genetics vol. 19, (3) 297-300.
10.1038/991
Gale RE, Mein CA, Linch DC(1996). Quantification of X-chromosome inactivation patterns in haematological samples using the DNA PCR-based HUMARA assay. Leukemia vol. 10, (2) 362-367.
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