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Publications:  Dr Jonas Bystrom

Bystrom J, Clanchy FI, Taher TE, Mangat P, Jawad AS, Williams RO, Mageed RA(2018). TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases. Cytokine vol. 101, 4-13.
10.1016/j.cyto.2016.09.001
Taher TE, Ong VH, Bystrom J, Hillion S, Simon Q, Denton CP, Pers J-O, Abraham DJ et al.(2017). Defective regulation of autoreactive IL-6-producing transitional B lymphocytes is associated with disease in patients with systemic sclerosis. Arthritis Rheumatol
10.1002/art.40390
Taher TE, Bystrom J, Ong VH, Isenberg DA, Renaudineau Y, Abraham DJ, Mageed RA(2017). Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity. Clin Rev Allergy Immunol vol. 53, (2) 237-264.
10.1007/s12016-017-8609-4
Bystrom J, Clanchy FI, Taher TE, Al-Bogami MM, Muhammad HA, Alzabin S, Mangat P, Jawad AS et al.(2017). Response to Treatment with TNFα Inhibitors in Rheumatoid Arthritis Is Associated with High Levels of GM-CSF and GM-CSF+ T Lymphocytes. Clin Rev Allergy Immunol vol. 53, (2) 265-276.
10.1007/s12016-017-8610-y
Amin K, Rasool AH, Hattem A, Al-Karboly TA, Taher TE, Bystrom J(2017). Autoantibody profiles in autoimmune hepatitis and chronic hepatitis C identifies similarities in patients with severe disease. World J Gastroenterol vol. 23, (8) 1345-1352.
10.3748/wjg.v23.i8.1345
Amin K, Janson C, Bystrom J(2016). Role of Eosinophil Granulocytes in Allergic Airway Inflammation Endotypes. Scandinavian Journal of Immunology vol. 84, (2) 75-85.
10.1111/sji.12448
Gilroy DW, Edin ML, De Maeyer RPH, Bystrom J, Newson J, Lih FB, Stables M, Zeldin DC et al.(2016). CYP450-derived oxylipins mediate inflammatory resolution. Proceedings of the National Academy of Sciences of USA vol. 113, (23) E3240-E3249.
10.1073/pnas.1521453113
Al-Bogami MM, Alkhorayef MA, Bystrom J, Akanle OA, Al-Adhoubi NK, Jawad AS, Mageed RA(2015). Favorable therapeutic response of osteoporosis patients to treatment with intravenous zoledronate compared with oral alendronate. Saudi Med J vol. 36, (11) 1305-1311.
10.15537/smj.2015.11.12731
Bystrom J, Taher TE, Muhyaddin MS, Clanchy FI, Mangat P, Jawad AS, Williams RO, Mageed RA(2015). Harnessing the Therapeutic Potential of Th17 Cells. Mediators Inflamm vol. 2015,
10.1155/2015/205156
Bystrom J, Taher T, Al-Bogami M, Alzabin S, Kelly S, Mangat P, Williams R, Jawad A et al. (2014). CYTOKINE PRODUCTION IDENTIFIES A SUBSET OF RHEUMATOID ARTHRITIS PATIENTS T LYMPHOCYTES THAT IS ASSOCIATED WITH RESPONSIVENESS TO BIOLOGIC ANTI-TNF-ALPHA AGENTS. ANNALS OF THE RHEUMATIC DISEASES. vol. 73, 356-356.
10.1136/annrheumdis-2014-eular.4637
Bystrom J, O'Shea NR(2014). Eosinophilic oesophagitis: clinical presentation and pathogenesis. Postgrad Med J vol. 90, (1063) 282-289.
10.1136/postgradmedj-2012-131403
Bystrom J, Al-Adhoubi N, Al-Bogami M, Jawad AS, Mageed RA(2013). Th17 lymphocytes in respiratory syncytial virus infection. Viruses vol. 5, (3) 777-791.
10.3390/v5030777
Bystrom J, Thomson SJ, Johansson J, Edin ML, Zeldin DC, Gilroy DW, Smith AM, Bishop-Bailey D(2013). Inducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?. PLoS One vol. 8, (9)
10.1371/journal.pone.0075107
Bystrom J, Patel SY, Amin K, Bishop-Bailey D(2012). Dissecting the role of eosinophil cationic protein in upper airway disease. Curr Opin Allergy Clin Immunol vol. 12, (1) 18-23.
10.1097/ACI.0b013e32834eccaf
Stables MJ, Shah S, Camon EB, Lovering RC, Newson J, Bystrom J, Farrow S, Gilroy DW(2011). Transcriptomic analyses of murine resolution-phase macrophages. Blood vol. 118, (26) e192-e208.
10.1182/blood-2011-04-345330
Bystrom J, Amin K, Bishop-Bailey D(2011). Analysing the eosinophil cationic protein--a clue to the function of the eosinophil granulocyte. Respir Res vol. 12,
10.1186/1465-9921-12-10
Bystrom J, Wray JA, Sugden MC, Holness MJ, Swales KE, Warner TD, Edin ML, Zeldin DC et al.(2011). Endogenous epoxygenases are modulators of monocyte/macrophage activity. PLoS One vol. 6, (10)
10.1371/journal.pone.0026591
Hou TZ, Bystrom J, Sherlock JP, Qureshi O, Parnell SM, Anderson G, Gilroy DW, Buckley CD(2010). A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis. FEBS Lett vol. 584, (18) 3955-3961.
10.1016/j.febslet.2010.07.053
Navarro-Xavier RA, Newson J, Silveira VLF, Farrow SN, Gilroy DW, Bystrom J(2010). A new strategy for the identification of novel molecules with targeted proresolution of inflammation properties. J Immunol vol. 184, (3) 1516-1525.
10.4049/jimmunol.0902866
Bishop-Bailey D, Bystrom J(2009). Emerging roles of peroxisome proliferator-activated receptor-beta/delta in inflammation. Pharmacol Ther vol. 124, (2) 141-150.
10.1016/j.pharmthera.2009.06.011
Bystrom J, Evans I, Newson J, Stables M, Toor I, van Rooijen N, Crawford M, Colville-Nash P et al.(2008). Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP. Blood vol. 112, (10) 4117-4127.
10.1182/blood-2007-12-129767
Stables MJ, Newson JS, Bystrom J, Ayoub SS, Gilroy DW(2008). COX-1 modulates the inflammatory macrophage phenotype and the host's ability to fight infection. FUND CLIN PHARMACOL vol. 22, 47-47.
Newson J, Stables M, Bystrom J, Colville-Nash P, Bellingan G, Gilroy D(2008). Lymphocyte trafficking at resolution is mediated by PGD2, via iNOS nitroslyation of COX-2. FUND CLIN PHARMACOL vol. 22, 23-23.
Bystrom J, Evans I, Newson J, Stables M, Toor I, Crawford M, Colville-Nash P, Farrow S et al.(2008). Resolution-phase macrophages possess a unique inflammatory and bactericidal phenotype that is controlled by CAMP. FUND CLIN PHARMACOL vol. 22, 47-47.
Rajakariar R, Lawrence T, Bystrom J, Hilliard M, Colville-Nash P, Bellingan G, Fitzgerald D, Yaqoob MM et al.(2008). Novel biphasic role for lymphocytes revealed during resolving inflammation. Blood vol. 111, (8) 4184-4192.
10.1182/blood-2007-08-108936
Trulson A, Byström J, Engström A, Larsson R, Venge P(2007). The functional heterogeneity of eosinophil cationic protein is determined by a gene polymorphism and post-translational modifications. Clin Exp Allergy vol. 37, (2) 208-218.
10.1111/j.1365-2222.2007.02644.x
Byström J, Dyer KD, Ting-De Ravin SS, Naumann N, Stephany DA, Foster PS, Wynn TA, Rosenberg HF(2006). Interleukin-5 does not influence differential transcription of transmembrane and soluble isoforms of IL-5R alpha in vivo. Eur J Haematol vol. 77, (3) 181-190.
10.1111/j.1600-0609.2006.00699.x
Jönsson U-B, Byström J, Stålenheim G, Venge P(2006). A (G->C) transversion in the 3' UTR of the human ECP (eosinophil cationic protein) gene correlates to the cellular content of ECP. J Leukoc Biol vol. 79, (4) 846-851.
10.1189/jlb.0904517
Nitto T, Dyer KD, Mejia RA, Byström J, Wynn TA, Rosenberg HF(2004). Characterization of the divergent eosinophil ribonuclease, mEar 6, and its expression in response to Schistosoma mansoni infection in vivo. Genes Immun vol. 5, (8) 668-674.
10.1038/sj.gene.6364143
Swartz JM, Byström J, Dyer KD, Nitto T, Wynn TA, Rosenberg HF(2004). Plasminogen activator inhibitor-2 (PAI-2) in eosinophilic leukocytes. J Leukoc Biol vol. 76, (4) 812-819.
10.1189/jlb.0304182
Nitto T, Dyer KD, Bystrom J, Mejia RA, Wynn TA, Rosenberg HF (2004). IL-5 dependent regulation of eosinophil ribonuclease gene expression. FASEB JOURNAL. vol. 18, A416-A416.
Byström J, Wynn TA, Domachowske JB, Rosenberg HF(2004). Gene microarray analysis reveals interleukin-5-dependent transcriptional targets in mouse bone marrow. Blood vol. 103, (3) 868-877.
10.1182/blood-2003-08-2778
Bystrom J, Swartz JM, Wynn TA, Domachowske JB, Rosenberg HF (2004). Interleukin-5 and gene transcription in mouse bone marrow in vivo. IMMUNOLOGY 2004: GENOMIC ISSUES, IMMUNE SYSTEM ACTIVATION AND ALLERGY. 9-14.
Nitto T, Mejia RA, Bystrom J, Dyer KD, Wynn TA, Rosenberg HF (2003). IL-5 dependent regulation of eosinophil ribonuclease gene expression. BLOOD. vol. 102, 524A-524A.
Byström J, Garcia RC, Håkansson L, Karawajczyk M, Moberg L, Soukka J, Venge P(2002). Eosinophil cationic protein is stored in, but not produced by, peripheral blood neutrophils. Clin Exp Allergy vol. 32, (7) 1082-1091.
10.1046/j.1365-2222.2002.01408.x
Jönsson U-B, Byström J, Stålenheim G, Venge P(2002). Polymorphism of the eosinophil cationic protein-gene is related to the expression of allergic symptoms. Clin Exp Allergy vol. 32, (7) 1092-1095.
10.1046/j.1365-2222.2002.01410.x
Byström J, Tenno T, Håkansson L, Amin K, Trulson A, Högbom E, Venge P(2001). Monocytes, but not macrophages, produce the eosinophil cationic protein. APMIS vol. 109, (7-8) 507-516.
10.1111/j.1600-0463.2001.apm090704.x
Bystrom J, Garcia RC, Hakansson L, Karawajczyk M, Moberg L, Soukka J, Venge P(2000). Eosinophil cationic protein (ECP) is stored in, but not produced by neutrophils. BLOOD vol. 96, (11) 27B-27B.
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