Publications: Prof William Alazawi

Colosimo S, Miller H, Koutoukidis DA, Marjot T, Tan GD, Harman DJ, Aithal GP, Manousou P et al. ( 2024 ) . Glycated haemoglobin is a major predictor of disease severity in patients with NAFLD . Diabetes Research and Clinical Practice vol. 217 ,

Alazawi W ( 2024 ) . Update on Treatment for Metabolic Dysfunction-Associated Steatohepatitis Cirrhosis . Gastroenterology & hepatology vol. 20 , ( 4 ) 241 - 243 .

Brennan PN, Tavabie OD, Li W, Marjot T, Corless L, Fallowfield JA, Jarvis H, Mansour D et al. ( 2024 ) . Progress is impossible without change: understanding the evolving nomenclature of steatotic liver disease and its effect on hepatology practice . The Lancet Gastroenterology & Hepatology vol. 9 , ( 6 ) 577 - 582 .

Miller H, Harman D, Aithal GP, Manousou P, Cobbold JF, Parker R, Sheridan D, Newsome PN et al. ( 2024 ) . Translating the potential of the urine steroid metabolome to stage NAFLD (TrUSt-NAFLD): study protocol for a multicentre, prospective validation study . BMJ Open vol. 14 , ( 1 )

Saihi H, Bessant C, Alazawi W ( 2023 ) . Automated and reproducible cell identification in mass cytometry using neural networks . Briefings in Bioinformatics

James M, Alazawi W ( 2023 ) . Non-invasive Tests of Fibrosis: Does One Size Fit All? . Digestive Diseases and Sciences vol. 68 , ( 12 ) 4285 - 4286 .

Li W, Sheridan D, McPherson S, Alazawi W, Abeysekera K, Marjot T, Brennan P, Mahgoub S et al. ( 2023 ) . National study of NAFLD management identifies variation in delivery of care in the UK between 2019 to 2022 . JHEP Reports vol. 5 , ( 12 )

Lazarus JV, Mark HE, Allen AM, Arab JP, Carrieri P, Noureddin M, Alazawi W, Alkhouri N et al. ( 2023 ) . A global action agenda for turning the tide on fatty liver disease . Hepatology vol. 79 , ( 2 ) 502 - 523 .

Lazarus JV, Mark HE, Allen AM, Arab JP, Carrieri P, Noureddin M, Alazawi W, Alkhouri N et al. ( 2023 ) . A global research priority agenda to advance public health responses to fatty liver disease . Journal of Hepatology vol. 79 , ( 3 ) 618 - 634 .

Allen AM, Younossi ZM, Tsochatzis EA, Alazawi W, Zelber-Sagi S, Arab JP, Cusi K, Lazarus JV ( 2023 ) . Measuring NAFLD models of care . Nature Reviews Gastroenterology & Hepatology vol. 20 , ( 10 ) 626 - 627 .

Brindley JH, Abeysekera K, Hood G, Jennings S, Moore J, Hickman M, Alazawi W ( 2023 ) . Feasibility and acceptability of a primary care liver fibrosis testing pathway centred on the diabetes annual review: PRELUDE1 prospective cohort study protocol . BMJ Open vol. 13 , ( 5 )

Faloon S, Alazawi W ( 2023 ) . Renal dysfunction in liver disease . Medicine vol. 51 , ( J Hepatol 62 2015 ) 288 - 292 .

Waller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn W-K, Bessant C, Alazawi W ( 2022 ) . Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver disease . Clinical and Molecular Hepatology vol. 29 , ( 2 ) 417 - 432 .

Alazawi W ( 2022 ) . Myeloid XBP1 links lipid overload with inflammation in NASH: Do advances in basic science have clinical potential? . Journal of Hepatology vol. 77 , ( 2 ) 290 - 292 .

Spiers J, Brindley JH, Li W, Alazawi W ( 2022 ) . What’s new in non-alcoholic fatty liver disease? . Frontline Gastroenterology vol. 13 , ( e1 ) e102 - e108 .

Ho FK, Ferguson LD, Celis-Morales CA, Gray SR, Forrest E, Alazawi W, Gill JM, Katikireddi SV et al. ( 2022 ) . Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes: A prospective cohort study in the UK Biobank . EClinicalMedicine vol. 48 ,

McPherson S, Armstrong MJ, Cobbold JF, Corless L, Anstee QM, Aspinall RJ, Barclay ST, Brennan PN et al. ( 2022 ) . Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group . The Lancet Gastroenterology & Hepatology vol. 7 , ( 8 ) 755 - 769 .

Li W, Kadler BK, Brindley JH, Hood G, Devalia K, Loy J, Syn W-K, Alazawi W ( 2022 ) . The contribution of daytime sleepiness to impaired quality of life in NAFLD in an ethnically diverse population . Scientific Reports vol. 12 , ( 1 )

Macpherson I, Abeysekera KWM, Harris R, Mansour D, McPherson S, Rowe I, Rosenberg W, Dillon JF et al. ( 2022 ) . Identification of liver disease: why and how . Frontline Gastroenterology vol. 13 , ( 5 ) 367 - 373 .

Li W, Ng CH, Quek J, Chan KE, Tan C, Zeng RW, Yong JN, Tay H et al. ( 2022 ) . The growing prevalence of nonalcoholic fatty liver disease (NAFLD), determined by fatty liver index, amongst young adults in the United States. A 20-year experience . Metabolism and Target Organ Damage vol. 2 , ( 4 ) null - null .

Brown MJ, Alazawi W, Kanoni S ( 2021 ) . Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 . New England Journal of Medicine vol. 385 , ( 12 ) 1147 - 1149 .

Li W, Kadler BK, Brindley JH, Berryman V, Preston J, Pattrick M, Sutcliffe C, Hood G et al. ( 2021 ) . Undiagnosed obstructive sleep apnoea is a major component in NAFLD quality of life impairment . JOURNAL OF HEPATOLOGY . vol. 75 , S536 - S537 .

Alazawi W, Hirschfield G ( 2020 ) . Nonalcoholic Fatty Liver Disease . Liver Immunology , Springer Nature

Li W, Alazawi W ( 2020 ) . Non-alcoholic fatty liver disease . Clinical Medicine vol. 20 , ( 5 ) 509 - 512 .

Li W, Kemos P, Salciccioli JD, Marshall DC, Shalhoub J, Alazawi W ( 2020 ) . Socioeconomic Factors Associated With Liver-Related Mortality From 1985 to 2015 in 36 Developed Countries . Clinical Gastroenterology and Hepatology vol. 19 , ( 8 ) 1698 - 1707.e13 .

Younossi ZM, Anstee Q, Harrison S, Trauner M, Lawitz E, Wong VW-S, Okanoue T, Gomez MR et al. ( 2020 ) . FRI264 Improvements in the ELF test are associated with widespread changes in the hepatic transcriptome in patients with advanced fibrosis due to non-alcoholic steatohepatitis . Journal of Hepatology vol. 73 , s528 - s530 .

Brindley J, Tailor F, Chandrasekharan K, Waller K, Jong AV-D, Devalia K, Agrawal S, Rosini F et al. ( 2020 ) . SAT022 Simultaneous intra-operative sampling from multiple anatomical sites reveals pro-inflammatory liver homing T cells in liver, adipose tissue and peripheral blood in patients with NASH . Journal of Hepatology . vol. 73 ,

Anstee Q, Patel K, Laurent C, Shiffman M, M M, Chen C-Y, George Goh BB, Alazawi W et al. ( 2020 ) . THU047 Serious complications due to study-mandated liver biopsies in phase 3 trials for patients with advanced fibrosis due to non-alcoholic steatohepatitis . Journal of Hepatology vol. 73 ,

Heath H, Britton G, Kudo H, Renney G, Ward M, Hutchins R, Foster GR, Goldin RD et al. ( 2020 ) . Stat2 loss disrupts damage signalling and is protective in acute pancreatitis . The Journal of Pathology vol. 252 , ( 1 ) 41 - 52 .

Sattar N, Gill JMR, Alazawi W ( 2020 ) . Improving prevention strategies for cardiometabolic disease . Nature Medicine vol. 26 , ( 3 ) 320 - 325 .

Chandrasekharan K, Alazawi W ( 2020 ) . Genetics of Non-Alcoholic Fatty Liver and Cardiovascular Disease: Implications for Therapy? . Frontiers in Pharmacology vol. 10 ,

Hou W, Janech MG, Sobolesky PM, Bland AM, Samsuddin S, Alazawi W, Syn W-K ( 2020 ) . Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease . Bioscience Reports vol. 40 , ( 1 )

Kowdley KV, Alazawi W, Lanthier N, Iacob A, Torstenson R, Seyedkazemi S, Rodriguez-Araujo G, Abdelmalek MF et al. ( 2020 ) . IMPACT ON INFLAMMATORY BIOMARKERS, LIPIDS, AND CARDIOVASCULAR SAFETY OF CENICRIVIROC WITH OR WITHOUT STATINS IN SUBJECTS WITH NASH AND SIGNIFICANT LIVER FIBROSIS: CENTAUR STUDY . HEPATOLOGY . vol. 72 , 1050 - 1051 .

Li W, Homer K, Hull S, Boomla K, Robson J, Alazawi W ( 2019 ) . Obesity Predicts Liver Function Testing and Abnormal Liver Results . Obesity vol. 28 , ( 1 ) 132 - 138 .

Younossi ZM, Ratziu V, Loomba R, Rinella M, Anstee QM, Goodman Z, Bedossa P, Geier A et al. ( 2019 ) . Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial . The Lancet vol. 394 , ( 10215 ) 2184 - 2196 .

Michael E, Alazawi W ( 2019 ) . Non‐alcoholic fatty liver disease in men . Trends in Urology & Men's Health vol. 10 , ( 6 ) 6 - 9 .

Sattar N, Alazawi W ( 2019 ) . Authors’ reply to McKenna-Barry and Ryan . The BMJ vol. 367 ,

Alexander M, Loomis AK, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F et al. ( 2019 ) . Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults . BMJ vol. 367 , l5367 - l5367 .

Michael E, Nadarajah L, Blunden M, Alazawi W ( 2019 ) . Renal dysfunction in liver disease . Medicine vol. 47 , ( Hepatol [Internet] 34 2001 ) 679 - 683 .

Waller K, James C, de Jong A, Blackmore L, Ma Y, Stagg A, Kelsell D, O'Dwyer M et al. ( 2019 ) . ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis . Frontiers in Immunology vol. 10 ,

Alexander M, Loomis AK, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F et al. ( 2019 ) . Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts . BMC Medicine vol. 17 , ( 1 )

Li W, Britton G, Kudo H, Goldin RD, Alazawi W ( 2019 ) . FRI-279-Stat2 is a pathogenic factor in human non-alcoholic steatohepatitis and mouse models of liver injury and mediates fatty acid-induced Inflammasome activation in hepatocytes . Journal of Hepatology . vol. 70 ,

Waller K, Jong AV-D, Li W, Lowe R, Kemos P, Syn W-K, Alazawi W ( 2019 ) . FRI-356-Single cell peripheral innate and adaptive immune signature of non-alcoholic steatohepatitis by cytometry time of flight . Journal of Hepatology . vol. 70 , e551 - e552 .

Kadler B, Brindley JH, Berryman V, Preston J, Syn W-K, Alazawi W ( 2019 ) . THU-315-Non-cirrhotic patients with non-alcoholic fatty liver disease have impaired quality of life: Independently predicted by body mass index, diabetes and liver stiffness . Journal of Hepatology . vol. 70 ,

Nunez DJ, Alexander M, Yerges-Armstrong L, Singh G, Byttebier G, Fabbrini E, Waterworth D, Meininger G et al. ( 2018 ) . Factors influencing longitudinal changes of circulating liver enzyme concentrations in subjects randomized to placebo in four clinical trials . AJP Gastrointestinal and Liver Physiology vol. 316 , ( 3 ) g372 - g386 .

ALAZAWI W, Alexander M, Loomis AK, Fairburn-Beech J, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D et al. ( 2018 ) . Real world data reveal a diagnostic gap in non-alcoholic fatty liver disease . Real world data reveal a diagnostic gap in non-alcoholic fatty liver disease vol. 16 , ( 130 )

Dhalwani N, Alexander M, Loomis K, Sattar N, Waterworth D, Mosseveld M, Rijnbeek P, van der Lei J et al. ( 2018 ) . FRI-423 Non-invasive liver tests in electronic health records of patients with non-alcoholic fatty liver disease: combined analysis from four European countries . Journal of Hepatology . vol. 68 , s551 - s552 .

Li W, Homer K, Boomla K, Robson J, Hull S, Alazawi W ( 2018 ) . PS-062 Prevalence and explanatory factors for liver function testing and abnormality in a population-based study of children and young people . Journal of Hepatology . vol. 68 , s34 - s35 .

Alexander M, Loomis K, Dhalwani N, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A et al. ( 2018 ) . PS-106 Non-alcoholic fatty liver disease and relative risk of incident steatohepatitis, cirrhosis and hepatocellular carcinoma events in four European primary care databases . Journal of Hepatology . vol. 68 , s57 - s58 .

Heath H, Kudo H, Renney G, Ward M, Cutillas P, Goldin RD, Hutchins R, Foster G et al. ( 2018 ) . SAT-018 The pathogenic role of Stat2 in inflammation is independent of canonical interferon signaling and is mediated by TNFa . Journal of Hepatology . vol. 68 ,

Alazawi W, Knolle PA ( 2018 ) . Interfering with Kupffer cell replenishment: New insights into liver injury . Journal of Hepatology vol. 68 , ( 4 ) 635 - 637 .

Alexander M, Dhalwani NN, Rijnbeek P, Mosseveld M, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D et al. ( 2018 ) . Body mass index and the risk of cardiovascular disease and all-cause mortality in European primary care databases . PHARMACOEPIDEMIOLOGY AND DRUG SAFETY . vol. 27 , 81 - 81 .

Li W, Salciccioli JD, Marshall D, Shalhoub J, Alazawi W ( 2018 ) . Factors Influencing Global Trends in Liver-Related Mortality - an Observational Study from 1985 to 2015 . HEPATOLOGY . vol. 68 , 451A - 451A .

Alexander M, Loomis K, Dhalwani N, Van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A et al. ( 2018 ) . Non-Alcoholic Fatty Liver Disease and Risk of Acute Myocardial Infarction and Stroke: Analysis of 18 Million Patients in Four European Primary Care Databases . HEPATOLOGY . vol. 68 , 1323A - 1323A .

Alexander M, Loomis KA, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F et al. ( 2018 ) . Primary care recorded NAFLD and the risk of incident MI and stroke: Findings from analyses of 18 million patients in the UK, the Netherlands, Spain, and Italy . PHARMACOEPIDEMIOLOGY AND DRUG SAFETY . vol. 27 , 81 - 82 .

Heath H, Britton G, Kudo H, Renney G, Ward M, Goldin RD, Hutchins R, Foster GR et al. ( 2018 ) . Stat2 Deletion Impairs MAPK Signaling, NF-Kb Localisation to the Nucleus, Cytokine Expression and Is Protective from Sterile Inflammation . HEPATOLOGY . vol. 68 , 628A - 628A .

Alazawi W, Bernabe E, Tai D, Janicki T, Kemos P, Samsuddin S, Syn W-K, Gillam D et al. ( 2017 ) . Periodontitis is associated with significant hepatic fibrosis in patients with non-alcoholic fatty liver disease . PLoS One vol. 12 , ( 12 ) e0185902 - e0185902 .

De Silva S, Li W, Kemos P, Brindley JH, Mecci J, Samsuddin S, Chin-Aleong J, Feakins RM et al. ( 2017 ) . Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of South Asian descent . Frontline Gastroenterology vol. 9 , ( 2 )

Heath H, Renney G, Ward M, Cutillas P, Kudu H, Goldin R, Hutchins R, Foster G et al. ( 2017 ) . OC-080 Stat2 is a key mediator of acute pancreatitis . Gut . vol. 66 ,

De Silva S, Li W, Kemos P, Brindley J, Mecci J, Samsuddin S, Chin-Aleong J, Feakins R et al. ( 2017 ) . PWE-075 Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of south asian descent . Gut . Conference: Liver vol. 66 ,

Ratziu V, Wong VW-S, Lanthier N, Boursier J, Alazawi W, Kluwe J, Genesca J, Andreone P et al. ( 2017 ) . Hepatic fibrosis is associated with histological activity in nonalcoholic steatohepatitis: an analysis from a large database of screening biopsies in the CENTAUR trial . JOURNAL OF HEPATOLOGY . Conference: ™ EASL 2017 - European Association for the Study of the Liver ( Amsterdam, Holland ) from: 23/04/2017 to: 19/04/2017 , vol. 66 , S113 - S113 .

Sheridan DA, Aithal G, Alazawi W, Allison M, Anstee Q, Cobbold J, Khan S, Fowell A et al. ( 2017 ) . Care standards for non-alcoholic fatty liver disease in the United Kingdom 2016: a cross-sectional survey . Frontline Gastroenterology vol. 8 , ( 4 )

Shetty A, Cho W, Alazawi W, Syn W-K ( 2017 ) . Methotrexate Hepatotoxicity and the Impact of Nonalcoholic Fatty Liver Disease . The American Journal of the Medical Sciences vol. 354 , ( 2 ) 172 - 181 .

Alexander M, Loomis K, Fairburn-Beech J, van der Lei J, Duarte-Salles T, Ansell D, Pasqua A, Rijnbeek P et al. ( 2017 ) . LBP-528 Incidence and prevalence of recorded non-alcoholic fatty liver disease in four large European primary care databases covering 21.9 million adults . Journal of Hepatology . vol. 66 , s106 - s107 .

De Silva S, Li W, Kemos P, Brindley JH, Feakins R, Chinaleong J, Samsuddin S, Foster GR et al. ( 2017 ) . SAT-320 Blood-test based assessment of liver fibrosis, but not transient elastography, is less accurate in NAFLD patients of South Asian compared to White ethnicity . Journal of Hepatology . vol. 66 , s595 - s596 .

Alazawi W, Tai DF, Kemos P, Bernabe E, Janicki T, Gillam D, Samsuddin S, Syn WK et al. ( 2017 ) . SAT-321 Periodontitis is strongly associated with NAFLD in the NHANES III cohort and in an independent prospective study, is more common in those with biopsy-proven advanced compared to mild liver disease . Journal of Hepatology . vol. 66 ,

Joshi N, Goodhand J, Alazawi W, Das S, Wilks M, Rampton D ( 2016 ) . PWE-144 Predicting Treatment Failure in C.Difficile Infection: A Prospective Observational Cohort Study . Gut . vol. 65 ,

Alazawi W, Pirmadjid N, Lahiri R, Bhattacharya S ( 2016 ) . Inflammatory and Immune Responses to Surgery and Their Clinical Impact . Annals of Surgery vol. 264 , ( 1 ) 73 - 80 .

Tai D, Lewis H, Derwa Y, Lillis A, Reynolds T, Maitland K, Hall D, Alazawi W et al. ( 2015 ) . PTH-093 One year mortality outcomes of patients with liver cirrhosis admitted to a teaching hospital intensive care unit . Gut . vol. 64 ,

Alazawi W, Heath H, Petts G, Kudu H, Feakins R, O’Brien A, Goldin R, Foster G ( 2015 ) . PTH-102 Stat2 is a key inflammatory molecule in human non-alcoholic fatty liver disease and murine liver injury . Gut . vol. 64 ,

Gill, Hansi N, Payaniandy L, Schulz J, Payaniandy D, Alazawi W, Dearden J, Kallis Y et al. ( 2015 ) . PTU-117 Sequential NUC therapy following pegylated interferon provides a greater decline in HBSAG and potentially offers a treatment advantage over current therapies . Gut . vol. 64 ,

Lahiri R, Derwa Y, Bashir Z, Giles E, Torrance H, O’Dwyer M, Owen H, O’Brien A et al. ( 2015 ) . P0001 : Early monocyte dysfunction in patients who develop Systemic Inflammatory Response Syndrome (SIRS) and sepsis after hepatopancreaticobiliary surgery . Journal of Hepatology . vol. 62 , s290 - s291 .

Tai FWD, Syn W-K, Alazawi W ( 2015 ) . Practical approach to non‐alcoholic fatty liver disease in patients with diabetes . Diabetic Medicine vol. 32 , ( 9 ) 1121 - 1133 .

Pirmadjid N, Torrance HDT, Owen HC, Alazawi W, O'Dwyer MJ ( 2015 ) . Association Between Early Postoperatively Elevated TLR-4 & TLR-5 Gene Expression and Late Nosocomial Infection in Elective High-Risk Hepato-Pancreato-Biliary (HPB) Surgery . BRITISH JOURNAL OF SURGERY . vol. 102 , 2 - 2 .

Lahiri R, Derwa Y, Bashir Z, Giles E, Torrance HD, Owen HC, O'Dwyer MJ, O'Brien A et al. ( 2015 ) . Systemic Inflammatory Response Syndrome After Major Abdominal Surgery Predicted by Early Upregulation of TLR4 and TLR5 . Annals of Surgery vol. 263 , ( 5 ) 1028 - 1037 .

Hull S, Mathur R, Boomla K, Chowdhury TA, Dreyer G, Alazawi W, Robson J ( 2014 ) . Research into practice: understanding ethnic differences in healthcare usage and outcomes in general practice . British Journal of General Practice vol. 64 , ( 629 ) 653 - 655 .

Alazawi W, Mathur R, Abeysekera K, Hull S, Boomla K, Robson J, Foster GR ( 2014 ) . Ethnicity and the diagnosis gap in liver disease: a population-based study . Br J Gen Pract vol. 64 , ( 628 ) e694 - e702 .

Tai F, Derwa Y, Naik S, Alazawi W ( 2014 ) . PTH-080 Risk Profile For Non-alcoholic Fatty Liver Disease (nafld) In A Paediatric Specialist Care Setting . Gut vol. 63 Suppl 1 , A244 - A245 .

Alazawi W, Mathur R, Abeysekera K, Hull S, Boomla K, Robson J, Foster G ( 2014 ) . PTU-138 Population-based Study Of Ethnicity And The Diagnosis Gap In Liver Disease . Gut vol. 63 Suppl 1 ,

Ooi J, Chinthapalli S, O'Toole E, Alazawi W ( 2014 ) . PWE-142 Is Liver Disease Overlooked In Patients With Psoriasis? . Gut vol. 63 Suppl 1 ,

O'Brien AJ, Fullerton JN, Massey KA, Auld G, Sewell G, James S, Newson J, Karra E et al. ( 2014 ) . Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2 . Nat Med vol. 20 , ( 5 ) 518 - 523 .

O'Brien A, Fullerton J, Auld G, James S, Newson J, Karra E, Massey K, Alazawi W et al. ( 2014 ) . O154 PROSTAGLANDIN E2 MEDIATES IMMUNOSUPPRESSION IN ACUTELY DECOMPENSATED CIRRHOSIS . Journal of Hepatology . vol. 60 ,

Roberts SJ, Owen HC, Tam WL, Solie L, Van Cromphaut SJ, Van den Berghe G, Luyten FP ( 2013 ) . Humanized Culture of Periosteal Progenitors in Allogeneic Serum Enhances Osteogenic Differentiation and In Vivo Bone Formation . Stem Cells Translational Medicine vol. 3 , ( 2 ) 218 - 228 .

Alazawi W, Agarwal K, Suddle A, Aluvihare V, Heneghan MA ( 2013 ) . Maintaining clinical governance when giving telephone advice . Frontline Gastroenterology vol. 4 , ( 4 )

Lahiri R, Wong J, Bhattacharya S, Foster G, Alazawi W ( 2013 ) . OC-041 Enhanced Monocyte Function and Surface TLR Expression Predict Post-Operative Systemic Inflammatory Response Syndrome in Patients Immediately following Major Hepatic and Pancreatic Resection . Gut vol. 62 , ( Suppl 1 )

Alazawi W, Agarwal K, Suddle A, Aluvihare V, Heneghan M ( 2013 ) . PTH-178 Who Calls the Liver Registrar at King’S? . Gut . vol. 62 ,

Lahiri RP, Abeles A, Burnand KM, Alazawi W, Bhattacharya S, Foster GR, Knowles CH ( 2013 ) . A cross sectional study of colonic diverticulosis in the London Bangladeshi population . United European Gastroenterol J vol. 1 , ( 3 ) 191 - 197 .

Alazawi W, Heath H, Waters JA, Woodfin A, O'Brien AJ, Scarzello AJ, Ma B, Lopez-Otalora Y et al. ( 2013 ) . Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis . Proc Natl Acad Sci U S A vol. 110 , ( 21 ) 8656 - 8661 .

Alazawi W, Lahiri R, Spyrou A, Giles E, Bashir Z, O'Brien A, Stagg A, Waters J et al. ( 2013 ) . 319 PATIENTS WITH COMPENSATED CIRRHOSIS HAVE SELECTIVE PARESIS OF FLAGELLIN-INDUCED INNATE IMMUNE RESPONSES DUE TO FAILURES IN ERK SIGNALLING . Journal of Hepatology . vol. 58 , s133 - s134 .

Alazawi W, Abeysekera K, Dearden J, Glynn M, Kallis Y, Kennedy P, Marley R, Foster GR et al. ( 2013 ) . IMPLEMENTING EASL & AASLD GUIDELINES FOR HEPATOCELLULAR CARCINOMA SCREENING IS COST-EFFECTIVE IN LONDON'S ETHNICALLY DIVERSE POPULATION . JOURNAL OF HEPATOLOGY . vol. 58 , S397 - S397 .

Lahiri R, Wong J, Waters J, Bhattacharya S, Foster G, Alazawi W ( 2013 ) . Increased expression of toll-like receptor (TLR) 4 and TLR5 following complex hepato-pancreatico-biliary (HPB) surgery predicts the development of post-operative systemic inflammatory response syndrome (SIRS) . BRITISH JOURNAL OF SURGERY . vol. 100 , 20 - 21 .

Alazawi W, Abeysekera K, Boomla K, Foster GR ( 2013 ) . POPULATION BASED STUDY OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) SHOWS DISEASE IS MORE COMMON AMONG BANGLADESHIS IN ETHNICALLY DIVERSE BOROUGHS OF LONDON . JOURNAL OF HEPATOLOGY . vol. 58 , S530 - S530 .

Joshi NM, Kok K, Alazawi W, Goodhand J, Das SS, Rampton DS ( 2013 ) . RISES IN BOTH WHITE CELL COUNT AND CRP AT DAY 3 PREDICT FAILURE OF TREATMENT WITH METRONIDAZOLE IN C.DIFFICILE INFECTION . GUT . vol. 62 , A215 - A216 .

Lahiri R, Abeles A, Burnand K, Alazawi W, Foster G, Knowles C ( 2013 ) . The London Bangladeshi community: A population protected against the disease of western civilisation . BRITISH JOURNAL OF SURGERY . vol. 100 , 40 - 40 .

George PM, Cunningham ME, Galloway-Phillipps N, Badiger R, Alazawi W, Foster GR, Mitchell JA ( 2012 ) . Endothelin-1 as a mediator and potential biomarker for interferon induced pulmonary toxicity . Pulm Circ vol. 2 , ( 4 ) 501 - 504 .

George PM, Badiger R, Alazawi W, Foster GR, Mitchell JA ( 2012 ) . Pharmacology and therapeutic potential of interferons . Pharmacol Ther vol. 135 , ( 1 ) 44 - 53 .

Konishi H, Okamoto K, Ohmori Y, Yoshino H, Ohmori H, Ashihara M, Hirata Y, Ohta A et al. ( 2012 ) . An orally available, small-molecule interferon inhibits viral replication . Sci Rep vol. 2 ,

Patel C, Gill U, Alazawi W, Shaw P, Alstead EM, Kallis Y, Kooner P, Marley R et al. ( 2012 ) . Benchmarking disease activity and progression in Chronic Hepatitis B infected young adults . HEPATOLOGY . vol. 56 , 362A - 362A .

Patel C, Gill US, Alazawi W, Shaw P, Alstead E, Kallis Y, Kooner P, Marley R et al. ( 2012 ) . EVALUATION OF LIVER FIBROSIS IN YOUNG ADULT PATIENTS WITH CHRONIC HEPATITIS B VIRUS . GUT vol. 61 , A133 - A133 .

Alazawi W, Spyrou A, Lahiri R, Waters J, Foster GR ( 2012 ) . FLAGELLIN-INDUCED IL-6 PRODUCTION IS SELECTIVELY IMPAIRED IN PATIENTS WITH CIRRHOSIS . GUT vol. 61 , A130 - A130 .

Alazawi W, Waters JA, Heath H, Woodfin A, O'Brien A, Jacobs M, Goldin R, Nourshargh S et al. ( 2012 ) . Stat2 loss is associated with enhanced inflammatory cell egress and hepatitis after LPS stimulation despite abolishing inflammatory cytokine production: a novel model of liver inflammation . HEPATOLOGY . vol. 56 , 1098A - 1099A .

Alazawi W, Gamero A, Heath H, Smith P, Jacobs M, Waters J, Foster GR ( 2011 ) . P93 NFκB activation by TLR agonists is deficient in macrophages lacking STAT2 . Gut vol. 60 , ( Suppl 2 )

Buczacki S, Shalhoub J, George PM, Vearncombe LM, Byrne PD, Alazawi W ( 2011 ) . Benefits of knowledge-based interprofessional communication skills training in medical undergraduate education . JRSM Short Rep vol. 2 , ( 8 )

Glyn FJ, Gill U, Alazawi W, Ross V, Kooner P, Marley R, Foster G, Kennedy PT ( 2011 ) . Efficacy of Combination Tenofovir Plus Lamivudine Versus Tenofovir Monotherapy in Patients With Chronic Hepatitis B Virus . GASTROENTEROLOGY . vol. 140 , S455 - S455 .

Glyn F, Gill US, Alazawi W, Ross V, Kooner P, Marley R, Foster GR, Kennedy PTF ( 2011 ) . EFFICACY OF COMBINATION TENOFOVIR PLUS LAMIVUDINE VERSUS TENOFOVIR MONOTHERAPY IN PATIENTS WITH CHRONIC HEPATITIS B VIRUS . GUT . vol. 60 , A231 - A231 .

Goodhand JR, Alazawi W, Rampton D ( 2011 ) . SYSTEMATIC REVIEW: CLOSTRIDIUM DIFFICILE AND IBD . GUT . vol. 60 , A146 - A146 .

Goodhand JR, Alazawi W, Rampton DS ( 2011 ) . Systematic review: Clostridium difficile and inflammatory bowel disease . Aliment Pharmacol Ther vol. 33 , ( 4 ) 428 - 441 .

ALAZAWI W, Lewis H, Foster GR ( 2011 ) . Other Liver Viruses . Medicine vol. 39 , ( 9 ) 561 - 563 .

Javaid A, Hibbert L, Waters JA, Alazawi W, Foster GR ( 2010 ) . CAN AN EX VIVO HUMAN LIVER BIOPSY MODEL BE USED TO TEST THE EFFICACY OF DRUGS FOR THE TREATMENT OF HEPATITIS C? . HEPATOLOGY . vol. 52 , 1217A - 1217A .

Alazawi W, Cunningham M, Dearden J, Foster GR ( 2010 ) . Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection . Aliment Pharmacol Ther vol. 32 , ( 3 ) 344 - 355 .

Alazawi W, Vearncombe LM ( 2010 ) . Ready to Excel . Lulu

ALAZAWI W, Foster GR ( 2010 ) . Combination Therapy for Chronic Hepatitis B Virus Infection: Should we use it ab initio or Sequentially? . Clinical Dilemmas in Viral Liver Disease , Editors: Foster, G, Reddy, KR , Wiley-Blackwell

Simpson AI, Alazawi W, Warwick S, Sheridan E, Glynn M ( 2010 ) . Mycobacterium mucogenicum causing central line-related sepsis in a home parenteral nutrition patient . Proceedings of The Nutrition Society . vol. 69 ,

Alazawi W, Cunningham M, Dearden J, Foster GR ( 2010 ) . NATURAL HISTORY OF COMPENSATED CIRRHOSIS DUE TO CHRONIC HEPATITIS C INFECTION: A SYSTEMATIC REVIEW . GUT . vol. 59 , A101 - A101 .

Alazawi W ( 2010 ) . Case 36 Syncope in a Patient with Noonan Syndrome . Cases in Adult Congenital Heart Disease , Elsevier

Alazawi W, Cunningham M, Dearden J, Foster GR ( 2010 ) . NATURAL HISTORY OF COMPENSATED CIRRHOSIS DUE TO CHRONIC HEPATITIS C INFECTION: A SYSTEMATIC REVIEW . JOURNAL OF HEPATOLOGY . vol. 52 , S402 - S402 .

Alazawi W, Cottle R, Ross V, Ushiro-Lumb I, Alstead EM, Glynn M, Marley R, Foster GR ( 2009 ) . SUBSTITUTION OF ADEFOVIR FOR TENOFOVIR IN PATIENTS WITH CHRONIC HBV RECEIVING COMBINATION THERAPY WHO HAVE INCOMPLETE CONTROL OR VIROLOGICAL BREAKTHROUGH - IS IT WORTH-WHILE? . HEPATOLOGY . vol. 50 , 501A - 501A .

ALAZAWI W ( 2009 ) . Syncope in a Patient with Noonan Syndrome . Cases in Adult Congenital Heart Disease , Editors: Gatzoulis, MA, Gary D Webb, MD, Craig S Broberg, MD , Churchill Livingstone

Alazawi W, Gamero A, Waters J, Jacobs M, Foster G ( 2009 ) . STAT2 IS A MAJOR DETERMINANT OF HEPATIC INFLAMMATION AND MORTALITY IN A KNOCKOUT MOUSE MODEL OF PERITONEAL INFLAMMATION . JOURNAL OF HEPATOLOGY . vol. 50 , S307 - S307 .

Alazawi W, Foster GR ( 2008 ) . Advances in the diagnosis and treatment of hepatitis B . Curr Opin Infect Dis vol. 21 , ( 5 ) 508 - 515 .

Herdman MT, Pett MR, Roberts I, Alazawi WOF, Teschendorff AE, Zhang X-Y, Stanley MA, Coleman N ( 2006 ) . Interferon-β treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants . CARCINOGENESIS vol. 27 , ( 11 ) 2341 - 2353 .

Alazawi W, Pett M, Strauss S, Moseley R, Gray J, Stanley M, Coleman N ( 2004 ) . Genomic imbalances in 70 snap-frozen cervical squamous intraepithelial lesions: associations with lesion grade, state of the HPV16 E2 gene and clinical outcome . Br J Cancer vol. 91 , ( 12 ) 2063 - 2070 .

Morgan C, Alazawi W, Sirieix P, Freeman T, Coleman N, Fitzgerald R ( 2004 ) . In vitro acid exposure has a differential effect on apoptotic and proliferative pathways in a Barrett's adenocarcinoma cell line . Am J Gastroenterol vol. 99 , ( 2 ) 218 - 224 .

Pett MR, ALAZAWI W, Roberts I, Dowen S, Smith DI, Stanley MA, Coleman N ( 2004 ) . Acquisition of High-Level Chromosomal Instability Is Associated with Integration of Human Papillomavirus Type 16 in Cervical Keratinocytes . Cancer Research vol. 64 , ( 4 ) 1359 - 1368 .

Alazawi W, Gonzalez M, Abraham J, Arends M, Coleman N, Wilson C ( 2003 ) . Primary or secondary malignancy? Fingerprint evidence . Clin Oncol (R Coll Radiol) vol. 15 , ( 7 ) 408 - 411 .

Pett MR, Alazawi W, Dowen S, Roberts I, Stanley MA, Coleman N ( 2003 ) . Acquisition of high-level genomic instability is associated with integration of HPV16 in cervical keratinocytes . JOURNAL OF PATHOLOGY . vol. 201 , 4A - 4A .

Morgan C, Alazawi W, Sirieix P, Freeman T, Coleman N, Fitzgerald R ( 2003 ) . Immediate and early gene response to in vitro acid exposure in a Barrett's adenocarcinoma cell line . GUT . vol. 52 , A44 - A45 .

ALAZAWI W, Morris LS, Stanley MA, Garrod DR, Coleman N ( 2003 ) . Altered expression of desmosomal components in high-grade squamous intraepithelial lesions of the cervix . Virchows Archiv: the European Journal of Pathology vol. 443 , ( 1 ) 51 - 56 .

Alazawi W, Pett M, Arch B, Scott L, Freeman T, Stanley MA, Coleman N ( 2002 ) . Changes in cervical keratinocyte gene expression associated with integration of human papillomavirus 16 . Cancer Res vol. 62 , ( 23 ) 6959 - 6965 .

Alazawi W, Pett M, Freeman T, Stanley M, Coleman N ( 2002 ) . Changes in host cell genome and transcriptome associated with integration of HPV 16 in cervical keratinocytes . J PATHOL vol. 198 , 8A - 8A .