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Publications:  Prof Dave Curtis

Curtis D, Balloux F(2020). Editorial: Topical ethical issues in the publication of human genetics research. Annals of Human Genetics vol. 84, (4) 313-314.
10.1111/ahg.12382
Curtis D, Bakaya K, Sharma L, Bandyopadhyay S(2020). Weighted burden analysis of exome-sequenced late-onset Alzheimer's cases and controls provides further evidence for a role for PSEN1 and suggests involvement of the PI3K/Akt/GSK-3β and WNT signalling pathways. Annals of Human Genetics
10.1111/ahg.12375
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62958
Alexander M, CURTIS D(2020). LD scores are associated with differences in allele frequencies between populations but LD score regression can still distinguish confounding from polygenicity. Annals of Human Genetics
10.1111/ahg.12370
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62730
Lee PH, Anttila V, Won H, Feng YCA, Rosenthal J, Zhu Z, Tucker-Drob EM, Nivard MG et al.(2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell vol. 179, (7) 1469-1482.e11.
10.1016/j.cell.2019.11.020
Alliey-Rodriguez N, Grey TA, Shafee R, Asif H, Lutz O, Bolo NR, Padmanabhan J, Tandon N et al.(2019). NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Translational Psychiatry vol. 9, (1)
10.1038/s41398-019-0564-9
Curtis D(2019). A possible role for sarcosine in the management of schizophrenia. British Journal of Psychiatry vol. 215, (6) 697-698.
10.1192/bjp.2019.194
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62768
Balakrishna T, Curtis D(2019). Assessment of Potential Clinical Role for Exome Sequencing in Schizophrenia. Schizophr Bull
10.1093/schbul/sbz057
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58960
Gorman KM, Meyer E, Grozeva D, Spinelli E, McTague A, Sanchis-Juan A, Carss KJ, Bryant E et al.(2019). Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia. American Journal of Human Genetics vol. 104, (5) 948-956.
10.1016/j.ajhg.2019.03.005
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y et al.(2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics vol. 51, (5) 793-803.
10.1038/s41588-019-0397-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57717
Curtis D, Adlington K, Bhui KS(2019). Pursuing parity: Genetic tests for psychiatric conditions in the UK National Health Service. British Journal of Psychiatry vol. 214, (5) 248-250.
10.1192/bjp.2019.48
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56758
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD et al.(2019). Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics vol. 51, (4) 659-674.
10.1038/s41588-019-0364-4
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58641
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ et al.(2019). Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 180, (3) 223-231.
10.1002/ajmg.b.32716
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57639
CURTIS D(2019). Clinical relevance of genome‐wide polygenic score may be less than claimed. Annals of Human Genetics
10.1111/ahg.12302
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56614
Al Eissa MM, Sharp SL, O'Brien NL, Fiorentino A, Bass NJ, CURTIS D, McQuillin A(2019). Genetic Association and functional characterization of MCPH1 gene variation in bipolar disorder and schizophrenia. Amercian Journal of Medical Genetics Part B Neuropsychiatric Genetics
10.1002/ajmg.b.32722
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56517
CURTIS D, Tsavou A(2019). In-silico investigation of coding variants potentially affecting the functioning of the glutamatergic N-methyl-D-aspartate receptor in schizophrenia. Psychiatric Genetics
10.1097/YPG.0000000000000216
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58935
Curtis D (2019). A WEIGHTED BURDEN TEST USING LOGISTIC REGRESSION FOR INTEGRATED ANALYSIS OF SEQUENCE VARIANTS, COPY NUMBER VARIANTS AND POLYGENIC RISK SCORE. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 29, 1281-1282.
10.1016/j.euroneuro.2018.08.390
Hess JL, Tylee DS, Mattheisen M, Adolfsson R, Agartz I, Agerbo E, Albus M, Alexander M et al.(2019). A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry
10.1038/s41380-019-0463-8
Curtis D(2019). A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk score. European Journal of Human Genetics vol. 27, (1) 114-124.
10.1038/s41431-018-0272-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49463
Aleissa M, Bass N, McQuillin A, Sharp S, Fiorentino A, O'Brien N, Curtis D (2019). EXOME SEQUENCE ANALYSIS IDENTIFY RARE GENETIC VARIANT IMPLICATED IN SUSCEPTIBILITY TO SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 29, 1181-1181.
10.1016/j.euroneuro.2018.08.210
Aleissa M, Sharp S, Fiorentino A, O'Brien N, Bass N, Curtis D, McQuillin A (2019). GENETIC ASSOCIATION AND FUNCTIONAL CHARACTERIZATION OF A VARIANT IN THE MCPH1 GENE IN BIPOLAR DISORDER AND SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 29, S966-S967.
10.1016/j.euroneuro.2017.08.330
Aleissa M, Sharp SI, Brien NLO, Fiorentino A, Bass NJ, Curtis D, McQuillin A (2018). Genetic association and functional characterization of a variant in the MCPH1 gene in bipolar disorder and schizophrenia. EUROPEAN JOURNAL OF HUMAN GENETICS. vol. 26, 416-416.
Curtis D(2018). Polygenic risk score for schizophrenia is more strongly associated with ancestry than with schizophrenia. Psychiatr Genet vol. 28, (5) 85-89.
10.1097/YPG.0000000000000206
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44783
O'Brien NL, Fiorentino A, Curtis D, Rayner C, Petrosellini C, Al Eissa M, Bass NJ, McQuillin A et al.(2018). Rare variant analysis in multiply affected families, association studies and functional analysis suggest a role for the ITGΒ4 gene in schizophrenia and bipolar disorder. Schizophrenia Research vol. 199, 181-188.
10.1016/j.schres.2018.03.001
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36596
Ni G, Gratten J, Wray NR, Lee SH, Ripke S, Neale BM, Corvin A, Walters JTR et al.(2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports vol. 8, (1)
10.1038/s41598-018-28160-z
Curtis D, Emmett W(2018). Association study of schizophrenia with variants in miR-137 binding sites. Schizophrenia Research vol. 197, 346-348.
10.1016/j.schres.2017.11.018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/31327
LeBlanc M, Zuber V, Thompson WK, Andreassen OA, Frigessi A, Andreassen BK, Ripke S, Neale BM et al.(2018). A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework. BMC Genomics vol. 19, (1)
10.1186/s12864-018-4859-7
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ et al.(2018). Analysis of shared heritability in common disorders of the brain. Science vol. 360, (6395)
10.1126/science.aap8757
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42423
COELEWIJ L, CURTIS D(2018). Mini‐review: Update on the genetics of schizophrenia. Annals of Human Genetics
10.1111/ahg.12259
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42744
Ruderfer DM, Ripke S, McQuillin A, Boocock J, Stahl EA, Pavlides JMW, Mullins N, Charney AW et al.(2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell
10.1016/j.cell.2018.05.046
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39864
Ni G, Moser G, Ripke S, Neale BM, Corvin A, Walters JTR, Farh KH, Holmans PA et al.(2018). Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood. American Journal of Human Genetics
10.1016/j.ajhg.2018.03.021
Curtis D, Coelewij L, Liu SH, Humphrey J, Mott R(2018). Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology. Behavior Genetics vol. 48, (3) 198-208.
10.1007/s10519-018-9893-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36085
Gupta S, Akyuz E, Baldwin T, CURTIS D(2018). Community treatment orders in England: Review of usage from national data. BJPsych Bulletin
10.1192/bjb.2017.33
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38843
Curtis D(2018). Polygenic risk score for schizophrenia is not strongly associated with the expression of specific genes or gene sets. Psychiatr Genet
10.1097/YPG.0000000000000197
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45464
Al Eissa MM, Fiorentino A, Sharp SI, O'Brien NL, Wolfe K, Giaroli G, Curtis D, Bass NJ et al.(2018). Exome sequence analysis and follow up genotyping implicates rare ULK1 variants to be involved in susceptibility to schizophrenia. Annals of Human Genetics
10.1111/ahg.12226
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45465
Curtis D(2018). Construction of an Exome-Wide Risk Score for Schizophrenia Based on a Weighted Burden Test. Annals of Human Genetics vol. 82, (1) 11-22.
10.1111/ahg.12212
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26403
Curtis D (2017). Construction of an Exome-wide Risk Score for Schizophrenia Based on Weighted Burden Tests. GENETIC EPIDEMIOLOGY. vol. 41, 692-692.
Curtis D (2017). APPLICATION OF A WEIGHTED BURDEN TEST TO WHOLE EXOME SEQUENCE DATA FOR OBESITY AND SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 27, S195-S195.
O'Brien N, Fiorentino A, Sharp S, Way M, Morgan MY, Curtis D, Bass N, McQuillin A (2017). BIPOLAR RELATED FUNCTIONAL VARIANTS IN CALCIUM CHANNEL GENES. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 27, S146-S147.
Aleissa M, Bass N, McQuillin A, Curtis D, Sharp S, O'Brien N, Fiorentino A (2017). INVESTIGATION OF RARE GENETIC VARIATION IN SCHIZOPHRENIA AND BIPOLAR DISORDER. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 27, S189-S190.
Leonenko G, Richards AL, Walters JT, Pocklington A, Chambert K, Al Eissa MM, Sharp SI, O'Brien NL et al.(2017). Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 174, (7) 724-731.
10.1002/ajmg.b.32560
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25203
Curtis D, Derks EM(2017). Letter to the Editor: Schizophrenia does not represent the extreme of a normally distributed trait. Psychol Med1-2.
10.1017/S0033291717002422
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51243
Curtis D(2017). Association between smoking and psychosis may be mediated by maternal smoking during pregnancy. Psychol Med1-1.
10.1017/S0033291717002240
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25718
Hendricks AE, Bochukova EG, Marenne G, Keogh JM, Atanassova N, Bounds R, Wheeler E, Mistry V et al.(2017). Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity. Sci Rep vol. 7, (1) 4394-4394.
10.1038/s41598-017-03054-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33964
Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J, Torniainen M, Rees E, Iyegbe C et al.(2017). The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability. Nat Genet
10.1038/ng.3903
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25003
Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F et al.(2017). Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry vol. 7, (6) e1155-e1155.
10.1038/tp.2017.115
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25050
McLaughlin RL, Schijven D, Van Rheenen W, Van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A et al.(2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications vol. 8,
10.1038/ncomms14774
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45483
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A et al.(2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics vol. 49, (1) 27-35.
10.1038/ng.3725
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22706
Fiorentino A, O'Brien NL, Sharp SI, Curtis D, Bass NJ, McQuillin A(2016). Genetic variation in the miR-708 gene and its binding targets in bipolar disorder. Bipolar Disord vol. 18, (8) 650-656.
10.1111/bdi.12448
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19082
Johnson EC, Bjelland DW, Howrigan DP, Abdellaoui A, Breen G, Borglum A, Cichon S, Degenhardt F et al.(2016). No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study. PLoS Genet vol. 12, (10) e1006343-e1006343.
10.1371/journal.pgen.1006343
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34346
Curtis D(2016). Pathway analysis of whole exome sequence data provides further support for the involvement of histone modification in the aetiology of schizophrenia. Psychiatr Genet vol. 26, (5) 223-227.
10.1097/YPG.0000000000000132
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25045
Al Eissa M, Fiorentino A, Sharp S, O'Brien NL, Giaroli G, Wolf K, Bass NJ, McQuillin A et al. (2016). Potential involvement of a CLSTN3 variant in susceptibility to schizophrenia. EUROPEAN NEUROPSYCHOPHARMACOLOGY. Conference: EUROPEAN NEUROPSYCHOPHARMACOLOGY vol. 26, S575-S576.
10.1016/S0924-977X(16)31635-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23547
Curtis D(2016). Schizophrenia genetics moves into the light. British Journal of Psychiatry vol. 209, (2) 93-94.
10.1192/bjp.bp.116.185405
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19072
Curtis JA, O'Brien NL, Curtis D, Fiorentino A, McQuillin A(2016). Association study of rare nonsynonymous variants of FTO in bipolar disorder. Psychiatr Genet vol. 26, (3) 140-141.
10.1097/YPG.0000000000000124
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19023
Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J, Suvisaari J, Chheda H et al.(2016). Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nature Neuroscience vol. 19, (4) 571-577.
10.1038/nn.4267
Franke B, van Hulzen KJE, Arias-Vasquez A, Bralten J, Hoogman M, Klein M, van Donkelaar MMJ, Hakobjan MMH et al.(2016). Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept. Nature Neuroscience vol. 19, (3) 420-431.
10.1038/nn.4228
Curtis D(2016). Practical Experience of the Application of a Weighted Burden Test to Whole Exome Sequence Data for Obesity and Schizophrenia. Annals of Human Genetics vol. 80, (1) 38-49.
10.1111/ahg.12135
Curtis D(2016). Rare missense variants within a single gene form yin yang haplotypes. European Journal of Human Genetics vol. 24, (1) 139-141.
10.1038/ejhg.2015.74
Hong Lee S, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AAE, Ripke S, Andreassen OA, Frisell T et al.(2015). New data and an old puzzle: The negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology vol. 44, (5) 1706-1721.
10.1093/ije/dyv136
Walter K, Min JL, Huang J, Crooks L, Memari Y, McCarthy S, Perry JRB, Xu C et al.(2015). The UK10K project identifies rare variants in health and disease. Nature vol. 526, (7571) 82-89.
10.1038/nature14962
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54492
Huang J, Howie B, McCarthy S, Memari Y, Walter K, Min JL, Danecek P, Malerba G et al.(2015). Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel. Nature Communications vol. 6,
10.1038/ncomms9111
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54488
Curtis D(2015). Investigation of Recessive Effects in Schizophrenia Using Next-Generation Exome Sequence Data. Annals of Human Genetics vol. 79, (5) 313-319.
10.1111/ahg.12109
Way M, McQuillin A, Saini J, Ruparelia K, Lydall GJ, Guerrini I, Ball D, Smith I et al.(2015). Genetic variants in or near adh1b and adh1c affect susceptibility to alcohol dependence in a british and irish population. Addiction Biology vol. 20, (3) 594-604.
10.1111/adb.12141
Grigoroiu-Serbanescu M, Curtis D, Noethen MM, Cichon S, McQuillin A (2015). Genome-wide Associated Schizophrenia Snps Do Not Predict Age-of-onset in Bipolar I Disorder. EUROPEAN PSYCHIATRY. vol. 30,
10.1016/S0924-9338(15)30912-3
Bulik-Sullivan B, Loh PR, Finucane HK, Ripke S, Yang J, Patterson N, Daly MJ, Price AL et al.(2015). LD score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics vol. 47, (3) 291-295.
10.1038/ng.3211
Maier R, Moser G, Chen GB, Ripke S, Coryell W, Potash JB, Scheftner WA, Shi J et al.(2015). Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. American Journal of Human Genetics vol. 96, (2) 283-294.
10.1016/j.ajhg.2014.12.006
O'Dushlaine C, Rossin L, Lee PH, Duncan L, Parikshak NN, Newhouse S, Ripke S, Neale BM et al.(2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. NATURE NEUROSCIENCE vol. 18, (2) 199-209.
10.1038/nn.3922
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7547
Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR et al.(2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics vol. 97, (4) 576-592.
10.1016/j.ajhg.2015.09.001
Taylor PN, Porcu E, Chew S, Campbell PJ, Traglia M, Brown SJ, Mullin BH, Shihab HA et al.(2015). Whole-genome sequence-based analysis of thyroid function. Nature Communications vol. 6,
10.1038/ncomms6681
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28888
Nurnberger J, Curtis D, Murray R, Blackwood D, Jarram A, Mors O(2014). In memoriam: Hugh Malcolm Douglas Gurling. Psychiatric genetics vol. 24, (6) 285-290.
10.1097/ypg.0000000000000063
Fiorentino A, O'Brien NL, Locke DP, McQuillin A, Jarram A, Anjorin A, Kandaswamy R, Curtis D et al.(2014). Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data. BIPOLAR DISORDERS vol. 16, (6) 583-591.
10.1111/bdi.12203
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23215
Kandaswamy R, McQuillin A, Curtis D, Gurling H(2014). Allelic Association, DNA Resequencing and Copy Number Variation at the Metabotropic Glutamate Receptor GRM7 Gene Locus in Bipolar Disorder. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS vol. 165, (4) 365-372.
10.1002/ajmg.b.32239
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23210
Curtis D(2014). OCTET does not demonstrate a lack of effectiveness for community treatment orders. BJPsych Bulletin vol. 38, (1) 36-39.
10.1192/pb.bp.113.044800
Timpson NJ, Walter K, Min JL, Tachmazidou I, Malerba G, Shin SY, Chen L, Futema M et al.(2014). A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans. Nature Communications vol. 5,
10.1038/ncomms5871
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54490
Ripke S, Neale BM, Corvin A, Walters JTR, Farh KH, Holmans PA, Lee P, Bulik-Sullivan B et al.(2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature vol. 511, (7510) 421-427.
10.1038/nature13595
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23686
Quadri G, McQuillin A, Guerrini I, Thomson AD, Cherian R, Saini J, Ruparelia K, Lydall GJ et al.(2014). Evidence for genetic susceptibility to the alcohol dependence syndrome from the thiamine transporter 2 gene solute carrier SLC19A3. Psychiatric Genetics vol. 24, (3) 122-123.
10.1097/YPG.0000000000000025
Sharp SI, Mcquillin A, Marks M, Hunt SP, Stanford SC, Lydall GJ, Morgan MY, Asherson P et al.(2014). Genetic association of the tachykinin receptor 1 TACR1 gene in bipolar disorder, attention deficit hyperactivity disorder, and the alcohol dependence syndrome. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 165, (4) 373-380.
10.1002/ajmg.b.32241
Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S et al.(2014). Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. American Journal of Human Genetics vol. 95, (5) 535-552.
10.1016/j.ajhg.2014.10.004
O'Brien N, Way M, Kandaswamy R, Fiorentino A, Sharp S, Quadri G, Alex J, Anjorin A et al.(2014). The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder. Psychiatric Genetics vol. 24, (6) 277-278.
10.1097/YPG.0000000000000050
Curtis D(2013). Consider factors that are important to patients when quantifying harms. BMJ (Online) vol. 347,
10.1136/bmj.f6614
Curtis D(2013). High prevalence and low fecundity of mental disorders may reflect recessive effects. JAMA Psychiatry vol. 70, (10)
10.1001/jamapsychiatry.2013.214
Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ et al.(2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet vol. 45, (9) 984-994.
10.1038/ng.2711
Kandaswamy R, McQuillin A, Sharp SI, Fiorentino A, Anjorin A, Blizard RA, Curtis D, Gurling HMD(2013). Genetic Association, Mutation Screening, and Functional Analysis of a Kozak Sequence Variant in the Metabotropic Glutamate Receptor 3 Gene in Bipolar Disorder. JAMA PSYCHIATRY vol. 70, (6) 591-598.
10.1001/jamapsychiatry.2013.38
Vincent PA, Curtis D(2013). Link between outcome and service quality is not clear. British Journal of Psychiatry vol. 202, (4)
10.1192/bjp.202.4.309
Curtis D(2013). Consideration of plausible genetic architectures for schizophrenia and implications for analytic approaches in the era of next generation sequencing. Psychiatr Genet vol. 23, (1) 1-10.
10.1097/YPG.0b013e32835d7e5a
Curtis D(2013). Approaches to the detection of recessive effects using next generation sequencing data from outbred populations. Adv Appl Bioinform Chem vol. 6, 29-35.
10.2147/AABC.S44332
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23943
Curtis S, Curtis D(2013). Report fails to acknowledge problems with at-home HIV test. The Lancet vol. 381, (9862) 203-204.
10.1016/S0140-6736(13)60090-2
Curtis D(2012). Thrombolysis in acute ischaemic stroke. LANCET vol. 380, (9847) 1054-1054.
10.1016/S0140-6736(12)61595-5
Kandaswamy R, McQuillin A, Curtis D, Gurling H(2012). Tests of linkage and allelic association between markers in the 1p36 PRKCZ (Protein Kinase C Zeta) gene region and bipolar affective disorder. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS vol. 159B, (2) 201-209.
10.1002/ajmg.b.32014
Curtis D(2012). A rapid method for combined analysis of common and rare variants at the level of a region, gene, or pathway. Adv Appl Bioinform Chem vol. 5, 1-9.
10.2147/AABC.S33049
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24522
Lydall GJ, Bass NJ, McQuillin A, Lawrence J, Anjorin A, Kandaswamy R, Pereira A, Guerrini I et al.(2011). Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder. Psychiatr Genet vol. 21, (6) 294-306.
10.1097/YPG.0b013e32834915c2
Curtis D(2011). Assessing the contribution family data can make to case-control studies of rare variants. Ann Hum Genet vol. 75, (5) 630-638.
10.1111/j.1469-1809.2011.00660.x
Pereira ACP, McQuillin A, Puri V, Anjorin A, Bass N, Kandaswamy R, Lawrence J, Curtis D et al.(2011). Genetic Association and Sequencing of the Insulin-Like Growth Factor 1 Gene in Bipolar Affective Disorder. AM J MED GENET B vol. 156B, (2) 177-187.
10.1002/ajmg.b.31153
Curtis D, Vine AE, McQuillin A, Bass NJ, Pereira A, Kandaswamy R, Lawrence J, Anjorin A et al.(2011). Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes. Psychiatr Genet vol. 21, (1) 1-4.
10.1097/YPG.0b013e3283413382
Curtis D(2011). Patient experience - the ingredient missing from cost-effectiveness calculations. Patient Prefer Adherence vol. 5, 251-254.
10.2147/PPA.S20243
Curtis D(2010). Antipsychotics and venous thrombosis: Confounding factors may account for the association. BMJ (Online) vol. 341, (7777)
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Raychaudhuri S, Korn JM, McCarroll SA, Altshuler D, Sklar P, Purcell S, Daly MJ, Stone J et al.(2010). Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genetics vol. 6, (9)
10.1371/journal.pgen.1001097
Datta SR, McQuillin A, Rizig M, Blaveri E, Thirumalai S, Kalsi G, Lawrence J, Bass NJ et al.(2010). A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia. Mol Psychiatry vol. 15, (6) 615-628.
10.1038/mp.2008.128
Nyegaard M, Severinsen JE, Als TD, Hedemand A, Straarup S, Nordentoft M, McQuillin A, Bass N et al.(2010). Support of Association Between BRD1 and Both Schizophrenia and Bipolar Affective Disorder. AM J MED GENET B vol. 153B, (2) 582-591.
10.1002/ajmg.b.31023
Lydall G, Bass N, McQuillin A, Anjorin A, Kandaswamy R, Pereira AC, Guerrini I, Curtis D et al.(2010). CONNECTIVITY GENES IN COMORBID ALCOHOLISM AND BIPOLAR DISORDER. EUROPEAN PSYCHIATRY vol. 25,
Lydall G, Worlley K, McQuillin A, Jauhar S, O'Kane A, Rao H, Anjorin A, Guerrini I et al. (2010). SEARCHING FOR ALCOHOLISM VULNERABILITY GENES: UK-COGA PROVISIONAL CLINICAL FINDINGS. EUROPEAN PSYCHIATRY. vol. 25,
Curtis D, Vine AE(2010). Yin yang haplotypes revisited - long, disparate haplotypes observed in European populations in regions of increased homozygosity. Hum Hered vol. 69, (3) 184-192.
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Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, Blackwood D, Curtis D et al.(2009). DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder. MOL PSYCHIATR vol. 14, (9) 865-873.
10.1038/mp.2008.22
Ng MYM, Levinson DF, Faraone SV, Suarez BK, DeLisi LE, Arinami T, Riley B, Paunio T et al.(2009). Meta-analysis of 32 genome-wide linkage studies of schizophrenia. MOL PSYCHIATR vol. 14, (8) 774-785.
10.1038/mp.2008.135
Vine AE, McQuillin A, Bass NJ, Pereira A, Kandaswamy R, Robinson M, Lawrence J, Anjorin A et al.(2009). No evidence for excess runs of homozygosity in bipolar disorder. PSYCHIAT GENET vol. 19, (4) 165-170.
10.1097/YPG.0b013e32832a4faa
Bass NJ, Datta SR, McQuillin A, Puri V, Choudhury K, Thirumalai S, Lawrence J, Quested D et al.(2009). Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia. BEHAV BRAIN FUNCT vol. 5, Article 28,
10.1186/1744-9081-5-28
McQuillin A, Bass NJ, Choudhury K, Puri V, Kosmin M, Lawrence J, Curtis D, Gurling HMD(2009). Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders. MOL PSYCHIATR vol. 14, (6) 614-620.
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Raychaudhuri S, Plenge RM, Rossin EJ, Ng ACY, Purcell SM, Sklar P, Scolnick EM, Xavier RJ et al.(2009). Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions. PLoS Genetics vol. 5, (6)
10.1371/journal.pgen.1000534
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Vine AE, Curtis D(2009). Markers typed in genome-wide analysis identify regions showing deviation from Hardy-Weinberg equilibrium. BMC Res Notes vol. 2,
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Curtis D, Vine AE, Knight J(2008). A simple method for assessing the strength of evidence for association at the level of the whole gene. Advances and Applications in Bioinformatics and Chemistry vol. 1, (1) 115-120.
Puri V, McQuillin A, Datta S, Choudhury K, Pimm J, Thirumalai S, Krasucki R, Lawrence J et al.(2008). Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3. EUR J HUM GENET vol. 16, (10) 1275-1282.
10.1038/ejhg.2008.76
Curtis D(2008). Effect of antipsychotics on stroke risk remains unproved. BMJ (Clinical research ed.) vol. 337,
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Curtis D(2008). Antipsychotics and stroke risk: Effect of antipsychotics on stroke risk remains unproved. BMJ vol. 337, (7671)
Knight J, Curtis D, Sham PC(2008). CLUMPHAP: A simple tool for performing haplotype-based association analysis. GENET EPIDEMIOL vol. 32, (6) 539-545.
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Ferreira MAR, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G et al.(2008). Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nature Genetics vol. 40, (9) 1056-1058.
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Curtis D, Vine AE, Knight J(2008). Investigation into the ability of SNP chipsets and microsatellites to detect association with a disease locus. Ann Hum Genet vol. 72, (Pt 4) 547-556.
10.1111/j.1469-1809.2008.00434.x
Sklar P, Smoller JW, Fan J, Ferreira MAR, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB et al.(2008). Whole-genome association study of bipolar disorder. Molecular Psychiatry vol. 13, (6) 558-569.
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Curtis D, Vine AE, Knight J(2008). Study of regions of extended homozygosity provides a powerful method to explore haplotype structure of human populations. Ann Hum Genet vol. 72, (Pt 2) 261-278.
10.1111/j.1469-1809.2007.00411.x
Curtis D, Vine AE, Knight J(2008). A simple method for assessing the strength of evidence for association at the level of the whole gene. Adv Appl Bioinform Chem vol. 1, 115-120.
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Stone JL, O'Donovan MC, Gurling H, Kirov GK, Blackwood DHR, Corvin A, Craddock NJ, Gill M et al.(2008). Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature vol. 455, (7210) 237-241.
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Curtis D(2007). Extended homozygosity is not usually due to cytogenetic abnormality. BMC Genet vol. 8,
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Datta SR, McQuillin A, Puri V, Choudhury K, Thirumalai S, Lawrence J, Pimm J, Bass N et al.(2007). Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia. BEHAV BRAIN FUNCT vol. 3, Article 50,
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Vine AE, Curtis D, Knight J (2007). A simple approach for assessing the strength of evidence for association at the level of the whole gene. GENETIC EPIDEMIOLOGY. vol. 31, 648-649.
Gurling HMD, Critchley H, Datta SR, McQuillin A, Blaveri E, Thirumalai S, Pimm J, Krasucki R et al.(2007). Gene-brain structure relationships: Arbitrary assumptions of heterogeneity generate unfalsifiable claims - Reply [4]. Archives of General Psychiatry vol. 64, (9) 1098-1099.
10.1001/archpsyc.64.9.1098
Willis M, Low LCM, Parkar S, Curtis D(2007). Psychiatry SHOs should consider psychological treatment for depression. Clinical Governance: An International Journal vol. 12, (3) 150-154.
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Curtis D(2007). Comparison of artificial neural network analysis with other multimarker methods for detecting genetic association. BMC Genet vol. 8,
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Curtis D, Xu K(2007). Minor differences in haplotype frequency estimates can produce very large differences in heterogeneity test statistics. BMC Genet vol. 8,
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Curtis D(2007). Allelic association studies of genome wide association data can reveal errors in marker position assignments. BMC Genet vol. 8,
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Curtis D, Vine AE, Knight J(2007). A pragmatic suggestion for dealing with results for candidate genes obtained from genome wide association studies. BMC Genet vol. 8,
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Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J et al.(2007). A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia. AM J HUM GENET vol. 80, (4) 664-672.
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Puri V, McQuillin A, Choudhury K, Datta S, Pimm J, Thirumalai S, Krasucki R, Lawrence J et al.(2007). Fine mapping by genetic association implicates the chromosome 1q23.3 gene UHMK1, encoding a serine/threonine protein kinase, as a novel schizophrenia susceptibility gene. BIOL PSYCHIAT vol. 61, (7) 873-879.
10.1016/j.biopsych.2006.06.014
North BV, Sham PC, Knight J, Martin ER, Curtis D(2006). Investigation of the ability of haplotype association and logistic regression to identify associated susceptibility loci. ANN HUM GENET vol. 70, 893-906.
10.1111/j.1469-1809.2006.00301.x
Townsend G, Curtis D(2006). Case report: Rapidly fatal bowel ischaemia on clozapine treatment. BMC Psychiatry vol. 6,
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Choudhury K, McQuillin A, Puri V, Thirumalai S, Lawrence J, Krasucki R, Datta SR, Bass NJ et al. (2006). A genetic association study implicates the chromosome 11q23.3 gene FXYD6 in susceptibility to schizophrenia. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 141B, 804-804.
Bass N, McQuillin A, Lawrence J, Choudhury K, Puri V, Kalsi G, Curtis D, Gurling H (2006). Failure to confirm allelic association between COMT and bipolar disorder in a large UK sample. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 141B, 749-749.
Kandaswamy R, Bass N, Choudhury K, Puri V, Mcquillin A, Lawrence J, Curtis D, Gurling H (2006). Fine mapping of a new bipolar and unipolar affective disorder locus on chromosome 1p36. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 141B, 747-748.
Kalsi G, McQuillin A, Degn B, Lundorf MD, Bass NJ, Lawrence J, Choudhury K, Puri V et al.(2006). Identification of the slynar gene (AY070435) and related brain expressed sequences as a candidate gene for susceptibility to affective disorders through allelic and haplotypic association with bipolar disorder on chromosome 12q24. AM J PSYCHIAT vol. 163, (10) 1767-1776.
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Curtis D, Gurling H(2006). Estimation of haplotypes at DRD2 may have produced misleading results [3]. Archives of General Psychiatry vol. 63, (8)
10.1001/archpsyc.63.8.939-a
Gurling HMD, Critchley H, Datta SR, McQuillin A, Blaveri E, Thirumalai S, Pimm J, Krasucki R et al.(2006). Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia. ARCH GEN PSYCHIAT vol. 63, (8) 844-854.
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Rizig MA, McQuillin A, Puri V, Choudhury K, Datta S, Thirumalai S, Lawrence J, Quested D et al.(2006). Failure to confirm genetic association between schizophrenia and markers on chromosome 1q23.3 in the region of the gene encoding the regulator of G-protein signaling 4 protein (RGS4). AM J MED GENET B vol. 141B, (3) 296-300.
10.1002/ajmg.b.30288
Curtis D, Sham PC(2006). Estimated haplotype counts from case-control samples cannot be treated as observed counts. AM J HUM GENET vol. 78, (4) 729-730.
10.1086/502666
Curtis D, Knight J, Sham PC(2006). Program Report: GENECOUNTING support programs. Annals of Human Genetics vol. 70, (2) 277-279.
10.1111/j.1529-8817.2005.00225.x
McQuillan A, Bass NJ, Kalsi G, Lawrence J, Puri V, Choudhury K, Detera-Wadleigh SD, Curtis D et al.(2006). Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3. MOL PSYCHIATR vol. 11, (2) 134-142.
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Puri V, McQuillin A, Thirumalai S, Lawrence J, Krasucki R, Choudhury K, Datta S, Kerwin S et al.(2006). Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample. BIOL PSYCHIAT vol. 59, (2) 195-197.
10.1016/j.biopsych.2005.08.015
McQuillin A, Kalsi G, Degn B, Lundorf MD, Bass NJ, Lawrence J, Choudhury K, Puri VH et al. (2005). Allelic and haplotypic association with bipolar disorder implicates a 300 kilobase region on chromosome 12q24.3 containing novel brain expressed gene sequences. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 138B, 32-32.
Datta SR, McQuillin A, Rizig MA, Puri V, Choudhury KH, Thirumalai S, Lawrence J, Bass N et al. (2005). Detection of potential aetiological base pair changes causing genetic susceptibility to schizophrenia in the pericentriolar material 1 (PCM1) gene on chromosome 8p22 supports evidence from allelic association. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 138B, 120-120.
Bass N, McQuillin A, Lawrence J, Choudhury, Puri V, Kalsi G, Curtis D, Gurling HM (2005). Evidence of allelic association of bipolar disorder with two genes P2RX7 and AY070435 6 MB apart on 12q24. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 138B, 74-74.
Choudhury KH, Rizig MA, McQuillin A, Puri V, Datta SR, Thirumalai S, Lawrence J, Bass N et al. (2005). Genetic association and gene expression studies implicate the chromosome 11q23.3 gene FXYD2 in susceptibility to schizophrenia. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 138B, 118-118.
Curtis D, Knight J, Sham PC(2005). A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees. Psychiatr Genet vol. 15, (3) 181-187.
10.1097/01.ypg.0000173119.04430.65
Vincent JB, Melmer G, Bolton PF, Hodgkinson S, Holmes D, Curtis D, Gurling HMD(2005). Genetic linkage analysis of the X chromosome in autism, with emphasis on the fragile X region. Psychiatric Genetics vol. 15, (2) 83-90.
10.1097/00041444-200506000-00004
Pimm J, McQuillin A, Thirumalai S, Lawrence J, Quested D, Bass N, Lamb G, Moorey H et al.(2005). The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. AM J HUM GENET vol. 76, (5) 902-907.
10.1086/430095
Guerrini I, Cook CCH, Kest W, Devitgh A, McQuillin A, Curtis D, Gurling HMD(2005). Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2. BMC GENET vol. 6, Article 11,
10.1186/1471-2156-6-11
North BV, Curtis D, Sham PC(2005). Application of logistic regression to case-control association studies involving two causative loci. HUM HERED vol. 59, (2) 79-87.
10.1159/000085222
Curtis D, Kerr M(2005). NICE recommendations for valproate treatment are unhelpful [5]. British Journal of Psychiatry vol. 186, (MAY)
10.1192/bjp.186.5.447
Rizig MA, McQuillin A, Datta SR, Pimm J, Thirumalai S, Moorey H, Quested DD, Kalsi G et al. (2004). A microarray gene expression and genetic association study of the RGS4 gene in schizophrenia. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 130B, 26-26.
Choudhury K, Puri V, McQuillin A, Kalsi G, Bass N, Lawrence J, Curtis D, Gurling HMD (2004). Attempted confirmation of the fine mapping of a putative bipolar susceptibility locus on chromosome 4P16.1 at the PPP2R2C gene locus. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 130B, 49-49.
Puri V, Rizig MA, Datta SR, McQuillin A, Thirumalai S, Pimm J, Moorey H, Quested D et al. (2004). Fine mapping of the chromosome 1q23-24.2 schizophrenia susceptibility region near the RGS4 D1S196 and Capon loci. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 130B, 129-129.
Datta SR, Mcqullin A, Rizig MA, Thirumalai S, Pimm J, Moorey H, Quested D, Kalsi G et al. (2004). Further genetic analyses of the PCM1 gene association with schizophrenia on chromosome 8p21 and tests of the G72, Dysbindin, RGS4, calcineurin, comt, frizzled 3, MRDS1, AKT1 and CAPON associations. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 130B, 86-86.
Kalsi G, McQuillan A, Degn B, Lundforf MD, Lawrence J, Curtis D, Kruse T, Gurling H et al. (2004). Identification of a locus increasing genetic susceptibility to bipolar affective disorder on chromosome 12q24.3 in both British/Irish and Danish case-control association samples. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. vol. 130B, 42-42.
Crossan I, Curtis D, Ong YL(2004). Audit of psychiatric discharge summaries: Completing the cycle. Psychiatric Bulletin vol. 28, (9) 329-331.
10.1192/pb.28.9.329
Curtis D(2004). Re-analysis of collaborative study on the genetics of alcoholism pedigrees suggests the presence of loci influencing novelty-seeking near D12S391 and D17S1299. Psychiatr Genet vol. 14, (3) 151-155.
10.1097/00041444-200409000-00006
Curtis D, Brett P, Dearlove AM, McQuillin A, Kalsi G, Robertson MM, Gurling HMD(2004). Genome scan of Tourette syndrome in a single large pedigree shows some support for linkage to regions of chromosomes 5, 10 and 13. PSYCHIAT GENET vol. 14, (2) 83-87.
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North BV, Curtis D, Martin ER, Lai EH, Roses AD, Sham PC(2004). Further investigation of linkage disequilibrium SNPs and their ability to identify associated susceptibility loci. Ann Hum Genet vol. 68, (Pt 3) 240-248.
10.1046/j.1529-8817.2004.00086.x
Sham PC, Rijsdijk FV, Knight J, Makoff A, North B, Curtis D(2004). Haplotype association analysis of discrete and continuous traits using mixture of regression models. BEHAV GENET vol. 34, (2) 207-214.
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Knight J, North BV, Sham PC, Curtis D (2003). Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait. BMC GENETICS. vol. 4,
10.1186/1471-2156-4-S1-S74
King AL, Moodie SJ, Fraser JS, Curtis D, Reid E, Dearlove AM, Ciclitira PJ(2003). Coeliac disease: investigation of proposed causal variants in the CTLA4 gene region. EUR J IMMUNOGENET vol. 30, (6) 427-432.
10.1111/j.1365-2370.2003.00430.x
North BV, Curtis D, Cassell PG, Hitman GA, Sham PC(2003). Assessing optimal neural network architecture for identifying disease-associated multi-marker genotypes using a permutation test, and application to calpain 10 polymorphisms associated with diabetes. Ann Hum Genet vol. 67, (Pt 4) 348-356.
10.1046/j.1469-1809.2003.00030.x
Curtis D, Kalsi G, Brynjolfsson J, McInnis M, O'Neill J, Smyth C, Moloney E, Murphy P et al.(2003). Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q. PSYCHIAT GENET vol. 13, (2) 77-84.
10.1097/01.ypg.0000056684.89558.d2
Carbonell J, Allen R, Kalsi G, McQuillin A, Livingston G, Katona C, Walker Z, Katz A et al.(2003). Variation in the DCP1 gene, encoding the angiotensin converting enzyme ACE, is not associated with increased susceptibility to Alzheimer's disease. Psychiatric Genetics vol. 13, (1) 47-50.
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North BV, Curtis D, Sham PC(2003). A note on the calculation of empirical P values from Monte Carlo procedures. AM J HUM GENET vol. 72, (2) 498-499.
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Knight J, North BV, Sham PC, Curtis D(2003). Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait. BMC genetics vol. 4 Suppl 1,
Gurling HMD, Blaveri E, Datta S, Kalsi G, McQuillin A, Moorey H, Quested D, Lamb G et al. (2002). Genetic markers showing linkage disequilibrium with a chromosome 8p22 schizophrenia susceptibility locus near the pericentriolar material gene (PCM1) are associated with reduced left orbitofrontal cortex grey matter volume and other cerebral morphology changes at MRI compared to non chromosome 8p22 associated schizophrenics. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 114, 747-747.
Guerrini I, Cook CH, Kest W, Devitgh A, McQuillin A, Curtis D, Gurling HMD (2002). Genome scan of alcoholism in multiplex British families supports the presence of susceptibility loci on chromosome 1p and 1q. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 114, 717-718.
Bass N, McQuillin A, Lawrence J, Darragh N, Kalsi G, Curtis D, Gurling HMD (2002). Investigation of the gene encoding tryptophan hydroxylase (TPH) and suicide behaviour in bipolar affective disorder shows allelic association with poor pre-morbid social and work adjustment and with violent suicide. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 114, 755-755.
McQuillin A, Kalsi G, Lawrence J, Smyth C, Curtis D, Bass N, Gurling HMD (2002). Positive allelic association of the marker D21S171 with bipolar disorder identifies TRPC7, a calcium channel protein on chromosome 21 at 21q22.3, as being a candidate gene for increasing susceptibility to bipolar and related unipolar affective disorders. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 114, 721-721.
Kalsi G, Lawrence J, Mcquillin A, Curtis D, Bass N, Gurling HMD (2002). X linkage in bipolar disorder: Allelic association studies of the Xq26-28 region implicate the G6PD locus and flanking region but not the a3 subunit of the GABA receptor gene (GABRA3) in a UK bipolar case-control sample. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 114, 764-764.
Gurting HMD, Blaveri E, Datta S, Kalsi G, Lawrence J, Quested D, Moorey H, Lamb G et al. (2002). Evidence for allelic association between three chromosome 8p21.3-22 markers and schizophrenia points to the brain expressed microtubule associated protein gene, Pericentriolar Material (PCM1) as a candidate for increasing genetic liability to schizophrenia. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 71, 469-469.
Blaveri E, Critchley HD, Gurling HMD, O'Daly O, Kalsi G, Datta SR, McQuillin A, Moorey H et al. (2002). Genetic markers showing linkage disequilibrium with a chromosome 8p22 schizophrenia susceptibility locus near the pericentriolar material gene (PCM1) are associated with reduced left orbitofrontal cortex grey matter volume and other cerebral morphology changes at MRI compared to non chromosome 8p22 associated schizophrenics. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 71, 469-469.
McQuillin A, Kalsi G, Lawrence J, Smyth C, Curtis D, Bass NJ, Gurling HMD (2002). Positive allelic association of the marker d21sl71 with bipolar disorder identifies TRPC7, a calcium channel protein on chromosome 21 at 21q22.3, as being a candidate gene for increasing genetic susceptibility to bipolar and related unipolar affective disorders. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 71, 488-488.
Hassan Z, Mohan V, Ali L, Allotey R, Barakat K, Faruque MO, Deepa R, McDermott MF et al.(2002). SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent. Am J Hum Genet vol. 71, (4) 964-968.
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North BV, Curtis D, Sham PC(2002). A note on the calculation of empirical P values from Monte Carlo procedures. AM J HUM GENET vol. 71, (2) 439-441.
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McQuillin A, Kalsi G, Moorey H, Lamb G, Mayet S, Quested D, Baker P, Curtis D et al.(2002). A novel polymorphism in exon 11 of the WKL1 gene, shows no association with schizophrenia. EUR J HUM GENET vol. 10, (8) 491-494.
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Moodie SJ, Norman PJ, King AL, Fraser JS, Curtis D, Ellis HJ, Vaughan RW, Ciclitira PJ(2002). Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters. EUR J IMMUNOGENET vol. 29, (4) 287-291.
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Curtis D, North BV, Gurling HMD, Blaveri E, Sham PC(2002). A quick and simple method for detecting subjects with abnormal genetic background in case-control samples. ANN HUM GENET vol. 66, 235-244.
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Cassell PG, Jackson AE, North BV, Evans JC, Syndercombe-Court D, Phillips C, Ramachandran A, Snehalatha C et al.(2002). Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians. Diabetes vol. 51, (5) 1622-1628.
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Taske NL, Williamson MP, Makoff A, Bate L, Curtis D, Kerr M, Kjeldsen MJ, Pang KA et al.(2002). Evaluation of the positional candidate gene CHRNA7 at the juvenile myoclonic epilepsy locus (EJM2) on chromosome 15q13-14. EPILEPSY RES vol. 49, (2) 157-172.
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Curtis D, North BV, Sham PC(2002). Extension of conditional model-free likelihood-based linkage analysis to additive and other models. ANN HUM GENET vol. 66, 157-167.
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King AL, Moodie SJ, Fraser JS, Curtis D, Reid E, Dearlove AM, Ellis HJ, Ciclitira PJ(2002). CTLA-4/CD28 gene region is associated with genetic susceptibility to coeliac disease in UK families. J MED GENET vol. 39, (1) 51-54.
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Guerrini I, Cook CCH, Kest W, Devitgh A, McQuillin A, Kalsi G, Curtis D, Gurling HMD(2001). Systematic genome scan of alcoholism using genetic linkage analysis in multiplex British families supports the presence of susceptibility loci on chromosome 1p and 16p. AM J HUM GENET vol. 69, (4) 498-498.
Curtis D, North BV, Sham PC(2001). A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. ANN HUM GENET vol. 65, 473-482.
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King AL, Fraser JS, Moodie SJ, Curtis D, Reid E, Dearlove AM, Ciclitira PJ(2001). CTLA-4 gene polymorphisms and susceptibility to coeliac disease. J MED GENET vol. 38, S67-S67.
Leung WC, Thornett AM, Curtis D, Chilvers C, Dewey M(2001). Antidepressants and counselling for major depression in primary care. BMJ vol. 323, (7307)
10.1136/bmj.323.7307.282
Blaveri E, Kalsi G, Lawrence J, Quested D, Moorey H, Lamb G, Kohen D, Shiwach R et al.(2001). Genetic association studies of schizophrenia using the 8p21-22 genes: Prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CNRNA2) and arylamine N-acetyltransferase 1 (NAT1). European Journal of Human Genetics vol. 9, (6) 469-472.
10.1038/sj.ejhg.5200646
King AL, Fraser JS, Moodle SJ, Curtis D, Dearlove AM, Ellis HJ, Rosen-Bronson S, Ciclitira PJ(2001). Coeliac disease: follow-up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11. ANN HUM GENET vol. 65, 377-386.
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King AL, Fraser JS, Moodie SJ, Curtis D, Dearlove AM, Ellis HJ, Rosen-Bronson S, Ciclitira PJ(2001). Follow-up linkage study of coeliac disease: Further evidence for the existence of a susceptibility locus on chromosome 11p11. GUT vol. 48, A77-A78.
Gurling HMD, Kalsi G, Brynjolfson J, Sigmundsson T, Sherrington R, Mankoo BS, Read T, Murphy P et al.(2001). Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. AM J HUM GENET vol. 68, (3) 661-673.
10.1086/318788
Crow TJ, Curtis D, Frangou S, Byrne P(2001). How to manage the first episode of schizophrenia. BMJ vol. 322, (7280)
10.1136/bmj.322.7280.234/a
Curtis D, North BV, Sham PC(2001). A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. Annals of Human Genetics vol. 65, (5) 473-482.
10.1046/j.1469-1809.2001.6550473.x
Curtis D(2001). How to manage the first episode of schizophrenia. Innovations in service provision need evidence, not opinion. BMJ (Clinical research ed.) vol. 322, (7280)
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Curtis D, North BV, Sham PC(2001). Use of an artificial neural network to detect association between a disease and multiple marker genotypes. ANN HUM GENET vol. 65, 95-107.
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Mynett-Johnson L, Kealey C, Claffey E, Curtis D, Bouchier-Hayes L, Powell C, McKeon P(2000). Multimarkerhaplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder. AM J MED GENET vol. 96, (6) 845-849.
10.1002/1096-8628(20001204)96:6<845::aid-ajmg30>3.0.co;2-r
King AL, Yiannakou JY, Brett PM, Curtis D, Morris MA, Dearlove AM, Rhodes M, Rosen-Bronson S et al.(2000). A genome-wide family-based linkage study of coeliac disease. Annals of Human Genetics vol. 64, (6) 479-490.
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Sham PC, Zhao JH, Waldman I, Curtis D(2000). Should ambiguous trios for the TDT be discarded?. Annals of Human Genetics vol. 64, (6) 575-576.
10.1017/S0003480000008368
Curtis D, Salonen JT, Tuomainen TP, Kontula K(2000). C282Y mutation and type 2 diabetes. BMJ vol. 321, (7271)
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Curtis D, Salonen JT, Tuomainen TP, Kontula K(2000). C282Y mutation and type 2 diabetes [6] (multiple letters). British Medical Journal vol. 321, (7271) 1288-1289.
10.1136/bmj.321.7271.1288
King AL, Yiannakou JY, Brett PM, Curtis D, Morris MA, Dearlove AM, Rhodes M, Rosen-Bronson S et al.(2000). A genome-wide family-based linkage study of coeliac disease. ANN HUM GENET vol. 64, 479-490.
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Sham PC, Zhao JH, Waldman I, Curtis D(2000). Should ambiguous trios for the TDT be discarded?. ANN HUM GENET vol. 64, 575-576.
10.1046/j.1469-1809.2000.6460575.x
Degn B, Lundorf MD, Bruun TG, McQuillin A, Lawrence J, Curtis D, Kalsi G, Chen A et al.(2000). A search for the risk allele for bipolar affective disorder on chromosome 12q24.2. AM J MED GENET vol. 96, (4) 545-546.
Gurling HMD, Curtis D, Kalsi G, McQuillan A, Lawrence J, Murphy P, Brynjolfsson J, McInnis M et al.(2000). Genome wide linkage anlaysis supports the presence of two separate susceptibility loci on chromosome 1q32 for biopolar disorder and 1q21-22.3 for schizophrenia. AM J MED GENET vol. 96, (4) 460-460.
Mynett-Johnson L, Kealey C, Claffey E, Curtis D, McKeon P(2000). Multi-marker haplotypes reveal evidence of an association between bipolar disorder and 5-HTT. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 96, (4)
Guerrini I, Cook CC, Kest W, Devitgh A, McQuillin A, Holmes D, Turner A, Curtis D et al.(2000). Report of a total genome scan for genes increasing susceptibility to alcoholism by genetic linkage analysis in multiplex British families. AM J MED GENET vol. 96, (4) 462-463.
Ogunkolade WB, Ramachandran A, McDermott MF, Kumarajeewa TR, Curtis D, Snehalatha C, Mohan V, Cassell PG et al.(2000). Family association studies of markers on chromosome 2q and Type 1 diabetes in subjects from South India. DIABETES METAB RES vol. 16, (4) 276-280.
10.1002/1520-7560(200007/08)16:4<276::aid-dmrr128>3.0.co;2-w
Zhao JH, Curtis D, Sham PC(2000). Model-free analysis and permutation tests for allelic associations. HUM HERED vol. 50, (2) 133-139.
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Sham PC, Zhao JH, Curtis D(2000). The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations. ANN HUM GENET vol. 64, 161-169.
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Morris MA, Yiannakou JY, King AL, Brett PM, Biagi F, Vaughan R, Curtis D, Ciclitira PJ(2000). Coeliac disease and Down syndrome: Associations not due to genetic linkage on chromosome 21. SCAND J GASTROENTERO vol. 35, (2) 177-180.
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Sham PC, Lin MW, Zhao JH, Curtis D(2000). Power comparison of parametric and nonparametric linkage tests in small pedigrees. American Journal of Human Genetics vol. 66, (5) 1661-1668.
10.1086/302888
Curtis D, Zhao JH, Sham PC (1999). Comparison of GENEHUNTER and MFLINK for analysis of COGA linkage data. Genetic Epidemiology. vol. 17,
Kalsi G, Gamble D, Curtis D, Brynjolfsson J, Sigmundsson T, Butler R, Read T, Murphy P et al.(1999). No evidence for linkage of schizophrenia to DXS7 at chromosome Xp11. PSYCHIATR GENET vol. 9, (4) 197-199.
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McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Hannesdottir S, Gurling H(1999). Adjacent genetic markers on chromosome 11p15.5 at or near the tyrosine hydroxylase locus that show population linkage disequilibrium with each other do not show allelic association with bipolar affective disorder. PSYCHOL MED vol. 29, (6) 1449-1454.
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Curtis D(1999). Cognitive therapy is no better than supportive counselling in schizophrenia [6]. British Medical Journal vol. 319, (7210)
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McQuillin A, Lawrence J, Kalsi G, Smyth C, Curtis D, Gurling HMD(1999). An allelic association study of multiple polymorphic markers in the chromosome 21q22.3 region implicated in bipolar affective disorder. MOL PSYCHIATR vol. 4, S76-S76.
Degn B, Bruun TG, McQuillin A, Lawrence J, Curtis D, Kalsi G, Chen A, Kruse TA et al.(1999). Association study between patients with bipolar disorder and markers from the candidate region on chromosome 12q24.2-12q24.3. MOL PSYCHIATR vol. 4, S71-S71.
Curtis D, Kalsi G, McQuillin A, Lawrence J, Murphy P, Brynjolfsson T, McInnis M, Sigmundsson T et al.(1999). Genome wide parametric genetic linkage analysis of bipolar and related unipolar affective disorders (manic depression) implicates chromosomes 1 and 12. MOL PSYCHIATR vol. 4, S70-S71.
Gurling HMD, Kalsi G, Blaveri E, McQuillin A, Read T, Murphy P, Butler R, Brynjolfsson J et al.(1999). Initial genome wide parametric genetic linkage analysis of schizophrenia and schizophrenia spectrum disorders finds lod scores above 3.00 on four chromosomes at 1Q22-23, 5Q22-35, 8P21-23 and 11Q14-24. a further lod above 3.00 at 4Q21-31 was found within a single family. MOL PSYCHIATR vol. 4, S4-S4.
Blaveri K, Kalsi G, McQuillin A, Quested D, Read T, Murphy P, Brynjolfsson J, Sigmundsson T et al.(1999). Linkage and allelic association studies of the 8p schizophrenia locus. MOL PSYCHIATR vol. 4, S31-S31.
Curtis D (1999). Chromosome 21 Workshop. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 88, 272-275.
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Curtis D (1999). Chromosome 21 workshop. American Journal of Medical Genetics - Neuropsychiatric Genetics. vol. 88, 272-275.
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Yiannakou JY, Brett PM, Morris MA, Curtis D, Mathew C, Vaughan R, Rosen-Bronson S, Ciclitira PJ(1999). Family linkage study of the T-cell receptor genes in coeliac disease. Italian Journal of Gastroenterology and Hepatology vol. 31, (3) 198-201.
Curtis D, Miller MB, Sham PC(1999). Combining the sibling disequilibrium test and transmission disequilibrium test for Multiallelic markers. AM J HUM GENET vol. 64, (6) 1785-1786.
10.1086/302421
Zhao JH, Sham PC, Curtis D(1999). A program for the Monte Carlo evaluation of significance of the extended transmission/disequilibrium test. AM J HUM GENET vol. 64, (5) 1484-1485.
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Brett PM, Yiannakou JY, Morris MA, Vaughan R, Curtis D, Ciclitira PJ(1999). Common HLA alleles, rather than rare mutants, confer susceptibility to coeliac disease. ANN HUM GENET vol. 63, 217-225.
10.1046/j.1469-1809.1999.6330217.x
Kalsi G, Mankoo B, Curtis D, Sherrington R, Melmer G, Brynjolfsson J, Sigmundsson T, Read T et al.(1999). New DNA markers with increased informativeness show diminished support for a chromosome 5q11-13 schizophrenia susceptibility locus and exclude linkage in two new cohorts of British and Icelandic families. ANN HUM GENET vol. 63, 235-247.
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Curtis D, Tarrier N(1999). Intensive cognitive behaviour therapy for chronic schizophrenia (multiple letters) [7]. British Medical Journal vol. 318, (7179)
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Curtis D, Zhao JH, Sham PC (1999). Comparison of GENEHUNTER and MFLINK for analysis of COGA linkage data. GENETIC EPIDEMIOLOGY. vol. 17, S115-S120.
10.1002/gepi.1370170720
McQuillin A, Lawrence J, Kalsi G, Chen A, Gurling H, Curtis D(1999). No allelic association between bipolar affective disorder and the tryptophan hydroxylase gene. Arch Gen Psychiatry vol. 56, (1) 99-101.
10.1001/archpsyc.56.1.99
McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Gurling HMD(1998). An allelic association study of candidate genes in the chromosome 21q22.3 region implicated in bipolar affective disorder. AM J MED GENET vol. 81, (6) 544-544.
McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Gurling HMD(1998). No allelic association between bipolar affective disorder and the tryptophan hydroxylase gene (TPH). AM J MED GENET vol. 81, (6) 513-513.
McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Gurling HMD(1998). No linkage found between chromosome 11p15.5 markers and manic-depressive illness. AM J MED GENET vol. 81, (6) 540-540.
Curtis D(1998). Genetic epidemiology of binging and vomiting. BRIT J PSYCHIAT vol. 173, 439-439.
10.1192/bjp.173.3.212
Bhandari S, Curtis D, Spitzer M(1998). Semantic priming in schizophrenia [7]. British Journal of Psychiatry vol. 173, (AUG.)
10.1192/bjp.173.2.184a
Vallada H, Curtis D, Sham P, Kunugi H, Zhao JH, Murray R, McGuffin P, Nanko S et al.(1998). A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12. SCHIZOPHR RES vol. 32, (2) 115-121.
10.1016/s0920-9964(98)00048-6
McDermott MF, McDermott EM, Quane KA, Jones LC, Ogunkolade BW, Curtis D, Waldron-Lynch F, Phelan M et al.(1998). Exclusion of the familial Mediterranean fever locus as a susceptibility region for autosomal dominant familial Hibernian fever. J MED GENET vol. 35, (5) 432-434.
10.1136/jmg.35.5.432
Williams J, Spurlock G, Holmans P, Mant R, Murphy K, Jones L, Cardno A, Asherson P et al.(1998). A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia. Molecular Psychiatry vol. 3, (2) 141-149.
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Brett PM, Yiannakou JY, Morris MA, Bronson SR, Mathew C, Curtis D, Ciclitira PJ(1998). A pedigree-based linkage study of coeliac disease: failure to replicate previous positive findings. ANN HUM GENET vol. 62, 25-32.
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Curtis D(1998). Efficient strategies for genome scanning with affected sib pairs. AM J HUM GENET vol. 62, (1) 204-205.
10.1086/301671
Morgan JF, Curtis D, Sullivan P(1998). Genetic epidemiology of binging and vomiting [1] (multiple letters). British Journal of Psychiatry vol. 173, (NOV.) 439-440.
Vallada HP, Vasques L, Curtis D, Zatz M, Kirov G, Lauriano V, Gentil V, Murray RM et al.(1998). Linkage analysis between bipolar affective disorder and markers on chromosome X. PSYCHIAT GENET vol. 8, (3) 183-186.
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Kalsi G, Curtis D, Brynjolfsson J, Sigmundsson T, Petursson H, Butler R, Read T, Murphy P et al.(1998). Tests of linkage, allelic and genotypic association between schizophrenia and the gene for the D3 dopamine receptor, DRD3. PSYCHIAT GENET vol. 8, (3) 187-189.
10.1097/00041444-199800830-00009
Goldin LR, Gershon ES, Berrettini WH, Stine OC, DePaulo R, McMahon F, Meyers D, Nothen M et al. (1997). Description of the genetic analysis workshop 10 bipolar disorder linkage data sets. Genetic Epidemiology. vol. 14, 563-568.
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Smyth C, Kalsi G, Brynjolfsson J, O'Neill J, Curtis D, Rifkin L, Moloney E, Murphy P et al.(1997). Test of Xq26.3-28 linkage In bipolar and unipolar affective disorder in families selected for absence of male to male transmission. BRIT J PSYCHIAT vol. 171, 578-581.
10.1192/bjp.171.6.578
Kalsi G, Curtis D, Brynjolfsson J, Sigmundsson T, Butler R, Read T, Murphy P, Petursson H et al. (1997). A linkage study between a D3 dopamine receptor (DRD3) gene polymorphism and schizophrenia. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 74, 626-626.
Lawrence J, Kalsi G, Hannesdottir S, Smyth C, Brynjolfsson J, Curtis D, Petursson H, Gurling HMD (1997). Further tests of allelic association and transmission disequilibrium between the tyrosine hydroxylase gene locus on chromosome 11p15 with bipolar and related unipolar affective disorders in familial and case-control samples. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 74, 669-670.
Kalsi G, Curtis D, Brynjolfsson J, Sigmundsson T, Butler R, Read T, Murphy P, Petursson H et al. (1997). Linkage analysis of the beta-1 GABAA receptor subunit gene locus in the genetic susceptibility to schizophrenia in British and Icelandic families. AMERICAN JOURNAL OF MEDICAL GENETICS. vol. 74, 635-636.
Brett PM, Curtis D, Robertson MM, Gurling HMD(1997). Neuroreceptor subunit genes and the genetic susceptibility to Gilles de la Tourette Syndrome. Biological Psychiatry vol. 42, (10) 941-947.
10.1016/S0006-3223(97)00140-6
Li T, Vallada H, Curtis D, Arranz M, Xu K, Cai GQ, Deng H, Liu J et al.(1997). Catechol-O-methyltransferase Val158Met polymorphism: frequency analysis in Han Chinese subjects and allelic association of the low activity allele with bipolar affective disorder. PHARMACOGENETICS vol. 7, (5) 349-353.
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Kalsi G, Smyth C, Brynjolfsson J, Sherrington RS, ONeill J, Curtis D, Rifkin L, Murphy P et al.(1997). Linkage analysis of manic depression (bipolar affective disorder) in Icelandic and British kindreds using markers on the short arm of chromosome 18. HUM HERED vol. 47, (5) 268-278.
10.1159/000154423
McDermott MF, Ramachandran A, Ogunkolade BW, Aganna E, Curtis D, Boucher BJ, Snehalatha C, Hitman GA(1997). Allelic variation in the vitamin D receptor influences susceptibility to IDDM in Indian Asians. DIABETOLOGIA vol. 40, (8) 971-975.
10.1007/s001250050776
Elmslie FV, Rees M, Williamson MP, Kerr M, Kjeldsen MJ, Pang KA, Sundqvist A, Friis ML et al.(1997). Genetic mapping of a major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q. HUM MOL GENET vol. 6, (8) 1329-1334.
10.1093/hmg/6.8.1329
Curtis D(1997). Use of siblings as controls in case-control association studies. ANN HUM GENET vol. 61, 319-333.
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Kellett JM, Curtis D(1997). Suspension of nurse who gave drug on consultant's instructions. BMJ vol. 314, (7086)
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Chen AC, Kalsi G, Brynjolfsson J, Sigmundsson T, Curtis D, Butler R, Read T, Murphy P et al.(1997). Exclusion of linkage between schizophrenia and the gene encoding a neutral amino acid glutamate/aspartate transporter, SLC1A5. Am J Med Genet vol. 74, (1) 50-52.
10.1002/(sici)1096-8628(19970221)74:1<50::aid-ajmg11>3.3.co;2-1
Fleminger S, Curtis D(1997). Prion diseases. BRIT J PSYCHIAT vol. 170, 103-105.
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Smyth C, Kalsi G, Curtis D, Brynjolfsson J, ONeill J, Rifkin L, Moloney E, Murphy P et al.(1997). Two-locus admixture linkage analysis of bipolar and unipolar affective disorder supports the presence of susceptibility loci on chromosomes 11p15 and 21q22. GENOMICS vol. 39, (3) 271-278.
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Chen ACH, Kalsi G, Brynjolfsson J, Sigmundsson T, Curtis D, Butler R, Read T, Murphy P et al.(1997). Exclusion of linkage of schizophrenia to the gene for the glutamate GluR5 receptor. Biological Psychiatry vol. 41, (2) 243-245.
10.1016/S0006-3223(96)00423-4
Goldin LR, Gershon ES, Berrettini WH, Stine OC, DePaulo R, McMahon F, Meyers D, Nothen M et al. (1997). Description of the Genetic Analysis Workshop 10 bipolar disorder linkage data sets. Genet Epidemiol. vol. 14, 563-568.
10.1002/(SICI)1098-2272(1997)14:6<563::AID-GEPI2>3.0.CO;2-0
Sham PC, Zhao JH, Curtis D(1997). Optimal weighting scheme for affected sib-pair analysis of sibship data. Annals of Human Genetics vol. 61, (1) 59-67.
10.1046/j.1469-1809.1997.6110059.x
Smyth C, Kalsi G, Brynjolfsson J, O'Neill J, Curtis D, Rifkin L, Moloney E, Murphy P et al.(1997). Test of Xq26.3-28 linkage in bipolar and unipolar affective disorder in families selected for absence of male to male transmission. British Journal of Psychiatry vol. 171, (DEC.) 578-581.
10.1192/bjp.171.6.578
Vallada H, Craddock N, Vasques L, Curtis D, Kirov G, Lauriano V, Gentil V, Passos-Bueno R et al.(1996). Linkage studies in bipolar affective disorder with markers on chromosome 21. Journal of Affective Disorders vol. 41, (3) 217-221.
10.1016/S0165-0327(96)00055-9
Kunugi H, Curtis D, Vallada HP, Nanko S, Powell JF, Murray RM, McGuffin P, Owen MJ et al.(1996). A linkage study of schizophrenia with DNA markers from chromosome 8p21-p22 in 25 multiplex families. Schizophrenia Research vol. 22, (1) 61-68.
10.1016/0920-9964(96)00048-5
Collier DA, Barrett TG, Curtis D, Macleod A, Arranz JM, Maassen JA, Bundey S(1996). Linkage of Wolfram syndrome to chromosome 4p16.1 and evidence for heterogeneity. AM J HUM GENET vol. 59, (4) 855-863.
Cook CCH, Palsson G, Turner A, Holmes D, Brett P, Curtis D, Petursson H, Gurling HMD(1996). A genetic linkage study of the D-2 dopamine receptor locus in heavy drinking and alcoholism. BRIT J PSYCHIAT vol. 169, (2) 243-248.
10.1192/bjp.169.2.243
Curtis D, Wang XL, Wilcken DEL(1996). Cardiovascular disease risk [2]. Nature Medicine vol. 2, (4) 365-366.
10.1038/nm0496-365
Woodgate M, Curtis D(1996). Prenatal exposure to the 1957 influenza epidemic. The British journal of psychiatry : the journal of mental science vol. 168, (6)
10.1192/bjp.168.6.791a
Sham PC, Curtis D, MacLean CJ, Terwilliger JD(1996). Likelihood ratio tests for linkage and linkage disequilibrium: Asymptomatic distribution and power [3]. American Journal of Human Genetics vol. 58, (5) 1093-1096.
Curtis D(1996). Genetic dissection of complex traits. NAT GENET vol. 12, (4) 356-357.
10.1038/ng0496-356
Gill M, Vallada H, Collier D, Sham P, Holmans P, Murray R, McGuffin P, Nanko S et al.(1996). A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22). Am J Med Genet vol. 67, (1) 40-45.
10.1002/(SICI)1096-8628(19960216)67:1<40::AID-AJMG6>3.0.CO;2-W
Chung E, Curtis D, Chen G, Marsden PA, Twells R, Xu W, Gardiner M(1996). Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis. American Journal of Human Genetics vol. 58, (2) 363-370.
Wildenauer DB, Schwab SG, Albus M, Hallmayer J, Lerer B, Maier W, Blackwood D, Muir W et al.(1996). Additional Support for Schizophrenia Linkage on Chromosomes 6 and 8: A Multicenter Study. American Journal of Medical Genetics vol. 67, (6) 580-594.
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Curtis D(1996). Defending attacks on statistics. Nature medicine vol. 2, (1) 4-5.
10.1038/nm0196-4a
Gurling H, Kalsi G, Chen ACH, Green M, Butler R, Read T, Murphy P, Curtis D et al.(1996). Erratum: Schizophrenia susceptibility and chromosome 6p24-22 (Nature Genetics (1995) 11 (234-235)). Nature Genetics vol. 13, (1)
10.1038/ng0596-129b
Lin MW, Curtis D, Williams N, Arranz M, Nanko S, Collier D, McGuffin P, Murray R et al.(1996). Erratum: Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32 (Psychiatric Genetics (1995) 5 (117-126). Psychiatric Genetics vol. 6, (1)
Smyth C, Kalsi G, Brynjolfsson J, O'Neill J, Curtis D, Rifkin L, Moloney E, Murphy P et al.(1996). Further tests for linkage of bipolar affective disorder to the tyrosine hydroxylase gene locus on chromosome 11p15 in a new series of multiplex British affective disorder pedigrees. American Journal of Psychiatry vol. 153, (2) 271-274.
10.1176/ajp.153.2.271
Chen ACH, Kalsi G, Brynjolfsson J, Sigmundsson T, Curtis D, Butler R, Read T, Murphy P et al.(1996). Lack of evidence for close linkage of the glutamate GluR6 receptor gene with schizophrenia. American Journal of Psychiatry vol. 153, (12) 1634-1636.
10.1176/ajp.153.12.1634
Brett PM, Curtis D, Robertson MM, Dahlitz M, Gurling HMD(1996). Linkage analysis and exclusion of regions of chromosomes 3 and 8 in Gilles de la Tourette syndrome following the identification of a balanced reciprocal translocation 46 XY, t(3:8)(p21.3 q24.1) in a case of Tourette syndrome. Psychiatric Genetics vol. 6, (3) 99-105.
10.1097/00041444-199623000-00001
Kalsi G, Sherrington R, Mankoo BS, Brynjolfsson J, Sigmundsson T, Curtis D, Read T, Murphy P et al.(1996). Linkage study of the D<inf>5</inf> dopamine receptor gene (DRD5) in multiplex Icelandic and English schizophrenia pedigrees. American Journal of Psychiatry vol. 153, (1) 107-109.
10.1176/ajp.153.1.107
Curtis D, Sham PC(1996). Population stratifications can cause false positive linkage results if founders are untyped. Annals of Human Genetics vol. 60, (3) 261-263.
10.1111/j.1469-1809.1996.tb00430.x
Sodhi MS, Arranz MJ, Curtis D, Ball DM, Sham P, Roberts GW, Price J, Collier DA et al.(1995). Association between clozapine response and allelic variation in the 5-HT2c receptor gene. NeuroReport vol. 7, (1) 169-172.
10.1097/00001756-199512000-00041
Kalsi G, Curtis D, Brynjolfsson J, Butler R, Sharma T, Murphy P, Read T, Petursson H et al.(1995). Investigation by linkage analysis of the XY pseudoautosomal region in the genetic susceptibility to schizophrenia. British Journal of Psychiatry vol. 167, (SEPT.) 390-393.
Curtis D(1995). Standardized pedigree nomenclature. American Journal of Human Genetics vol. 57, (4) 982-984.
Kalsi G, Curtis D, Brynjolfsson J, Butler R, Sharma T, Murphy P, Read T, Petursson H et al.(1995). Investigation by linkage analysis of the XY pseudoautosomal region in the genetic susceptibility to schizophrenia. Br J Psychiatry vol. 167, (3) 390-393.
10.1192/bjp.167.3.390
Kalsi G, Brynjolfsson J, Butler R, Sherrington R, Curtis D, Sigmundsson T, Read T, Murphy P et al.(1995). Linkage analysis of chromosome 22q12-13 in a United Kingdom/Icelandic sample of 23 multiplex schizophrenia families. American Journal of Medical Genetics - Neuropsychiatric Genetics vol. 60, (4) 298-301.
10.1002/ajmg.1320600407
Brett PM, Curtis D, Robertson MM, Gurling HMD(1995). The genetic susceptibility to Gilles de la Tourette Syndrome in a large multiple affected british kindred: Linkage analysis excludes a role for the genes coding for dopamine D1, D2, D3, D4, D5 receptors, dopamine beta hydroxylase, tyrosinase, and tyrosine hydroxylase. Biological Psychiatry vol. 37, (8) 533-540.
10.1016/0006-3223(94)00161-U
Curtis D, Sham PC(1995). A note on the application of the transmission disequilibrium test when a parent is missing [1]. American Journal of Human Genetics vol. 56, (3) 811-812.
SHAM PC, CURTIS D(1995). An extended transmission/disequilibrium test (TDT) for multi‐allele marker loci. Annals of Human Genetics vol. 59, (3) 323-336.
10.1111/j.1469-1809.1995.tb00751.x
Vallada H, Curtis D, Sham PC, Murray RM, McGuffin P, Nanko S, Gill M, Owen M et al.(1995). Chromosome 22 markers demonstrate transmission disequilibrium with schizophrenia. Psychiatric Genetics vol. 5, (3) 127-130.
10.1097/00041444-199505030-00005
Curtis D(1995). Euthanasia. Nature Medicine vol. 1, (9) 849-850.
10.1038/nm0995-849b
Kalsi G, Mankoo BS, Curtis D, Brynjolfsson J, Read T, Sharma T, Murphy P, Petursson H et al.(1995). Exclusion of linkage of schizophrenia to the gene for the dopamine D2 receptor (DRD2) and chromosome 11q translocation sites. Psychological Medicine vol. 25, (3) 531-537.
10.1017/S0033291700033456
Brett PM, Curtis D, Robertson MM, Gurling HMD(1995). Exclusion of the 5-HT<inf>1A</inf> serotonin neuroreceptor and tryptophan oxygenase genes in a large British kindred multiply affected with Tourette's syndrome, chronic motor tics, and obsessive-compulsive behavior. American Journal of Psychiatry vol. 152, (3) 437-440.
10.1176/ajp.152.3.437
Curtis D, Sham PC, Vallada HP(1995). Genetic analysis of complex disease. Nature Genetics vol. 9, (1)
10.1038/ng0195-13
Dawson E, Gill M, Curtis D, Castle D, Hunt N, Murray R, Powell J(1995). Genetic association between alleles of pancreatic phospholipase A2 gene and bipolar affective disorder. Psychiatric Genetics vol. 5, (4) 177-180.
10.1097/00041444-199524000-00005
Gurling H, Smyth C, Kalsi G, Moloney E, Rifkin L, O¿Neill J, Murphy P, Curtis D et al.(1995). Linkage findings in bipolar disorder. Nature Genetics vol. 10, (1) 8-9.
10.1038/ng0595-8b
Curtis D, Sham PC(1995). Model-free linkage analysis using likelihoods. American Journal of Human Genetics vol. 57, (3) 703-716.
SHAM PC, CURTIS D(1995). Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Annals of Human Genetics vol. 59, (1) 97-105.
10.1111/j.1469-1809.1995.tb01608.x
Gurling H, Kalsi G, Chen AHS, Green M, Butler R, Read T, Murphy P, Curtis D et al.(1995). Schizophrenia susceptibility and chromosome 6p24–22. Nature Genetics vol. 11, (3) 234-235.
10.1038/ng1195-234
Lin MW, Curtis D, Williams N, Arranz M, Nanko S, Collier D, McGuffin P, Murray R et al.(1995). Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32. Psychiatric Genetics vol. 5, (3) 117-126.
10.1097/00041444-199505030-00004
Sherrington R, Curtis D, Brynjolfsson J, Moloney E, Rifkin L, Petursson H, Gurling H(1994). A linkage study of affective disorder with DNA markers for the ABO-AK1-ORM linkage group near the dopamine beta hydroxylase gene. Biological Psychiatry vol. 36, (7) 434-442.
10.1016/0006-3223(94)90638-6
CURTIS D(1994). Another procedure for the preliminary ordering of loci based on two point lod scores. Annals of Human Genetics vol. 58, (1) 65-75.
10.1111/j.1469-1809.1994.tb00725.x
Rees M, Curtis D, Parker K, Sundqvist A, Baralle D, Bespalova IN, Burmeister M, Chung E et al.(1994). Linkage analysis of idiopathic generalised epilepsy in families of probands with juvenile myoclonic epilepsy and marker loci in the region of EPM 1 on chromosome 21 q: Unverricht-Lundborg disease and JME are not allelic variants. Neuropediatrics vol. 25, (1) 20-25.
10.1055/s-2008-1071576
Curtis D, Kalsi G, Gurling HM(1994). Pseudoautosomal linkage in schizophrenia. The British journal of psychiatry : the journal of mental science vol. 165, (1) 117-119.
10.1192/bjp.165.1.117b
Kalsi G, Mankoo BS, Brynjolfsson J, Curtis D, Read T, Murphy P, Sharma T, Petursson H et al.(1994). The marfan syndrome gene locus as a favoured locus for susceptibility to schizophrenia. Psychiatric Genetics vol. 4, (4) 219-227.
10.1097/00041444-199400440-00006
CURTIS D, SHAM PC(1994). Using risk calculation to implement an extended relative pair analysis. Annals of Human Genetics vol. 58, (2) 151-162.
10.1111/j.1469-1809.1994.tb01884.x
Lim LCC, Gurling H, Curtis D, Brynjolfsson J, Petursson H, Gill M(1993). Linkage between tyrosine hydroxylase gene and affective disorder cannot be excluded in two of six pedigrees. American Journal of Medical Genetics vol. 48, (4) 223-228.
10.1002/ajmg.1320480410
Curtis D, Brynjolfsson J, Petursson H, Holmes DS, Sherrington R, Brett P, Rifkin L, Murphy P et al.(1993). Corrigenda: Segregation and linkage analysis in five manic depression pedigrees excludes the 5HT1a receptor gene (HTR1A) (Annals of Human Genetics (1993) 57 (27-39)). Annals of Human Genetics vol. 57, (4)
Bateman JB, Kojis TL, Cantor RM, Heinzmann C, Ngo JT, Spence MA, Inana G, Kivlin JD et al. (1993). Linkage analysis of Norrie disease with an X-chromosomal ornithine aminotransferase locus. Transactions of the American Ophthalmological Society. vol. 91, 299-308.
KALSI G, SHERRINGTON R, MANKOO B, CURTIS D, MELMER G, BRYNJOLFSSON J, SHARMA T, SIGMUNDSSON T et al. (1993). GENOMIC CLONING, LOCALIZATION AND IDENTIFICATION OF A HIGHLY POLYMOROHIC MICROSATELLITE SEQUENCE FOR THE D5-DOPAMINE NEURORECEOTOR GENE LOCUS (DRD5) ON CHROMOSOME-4P WHICH SHOWS NO LINKAGE TO SCHIZOPHRENIA, MANIC-DEPRESSION AND TOURETTE SYNDROME. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 53, 1698-1698.
Brett P, Robertson M, Gurling H, Curtis D(1993). Failure to find linkage and increased homozygosity for the dopamine D3 receptor gene in Tourette's syndrome. The Lancet vol. 341, (8854)
10.1016/0140-6736(93)91064-S
Sherrington R, Kalsi G, Mankoo BS, Brynjolfsson J, Curtis D, Moloney E, Rifkin L, Petursson H et al.(1993). A linkage study with the D5 dopamine receptor in Icelandic pedigrees with multiple cases of manic depression. Psychiatric Genetics vol. 3, (4) 241-245.
Curtis D, Gurling H(1993). A procedure for combining two-point lod scores into a summary multipoint map. Human Heredity vol. 43, (3) 173-185.
10.1159/000154174
Sherrington R, Mankoo B, Attwood J, Kalsi G, Curtis D, Buetow K, Povey S, Gurling H(1993). Cloning of the Human Dopamine D5 Receptor Gene and Identification of a Highly Polymorphic Microsatellite for the DRD5 Locus That Shows Tight Linkage to the Chromosome 4p Reference Marker RAF1P1. Genomics vol. 18, (2) 423-425.
10.1006/geno.1993.1489
COOK CCH, GURLING HMD, CURTIS D(1993). DOLINK ‐ a computer program to facilitate management of genetic data and analyses. Annals of Human Genetics vol. 57, (4) 307-310.
10.1111/j.1469-1809.1993.tb00905.x
Curtis D, Sherrington R, Brett P, Holmes DS, Kalsi G, Brynjolfsson J, Petursson H, Rifkin L et al.(1993). Genetic linkage analysis of manic depression in Iceland. Journal of the Royal Society of Medicine vol. 86, (9) 506-510.
Whitehouse WP, Rees M, Curtis D, Sundqvist A, Parker K, Chung E, Baralle D, Gardiner RM(1993). Linkage analysis of idiopathic generalized epilepsy (IGE) and marker loci on chromosome 6p in families of patients with juvenile myoclonic epilepsy: No evidence for an epilepsy locus in the HLA region. American Journal of Human Genetics vol. 53, (3) 652-662.
Sherrington R, Mankoo B, Dixon M, Curtis D, Kalsi G, Melmer G, Gurling H(1993). Microsatellite polymorphisms for chromosome 5 bands q11.2-q13.3. Human Heredity vol. 43, (3) 197-202.
10.1159/000154177
CURTIS D, BRYNJOLFSSON J, PETURSSON H, HOLMES S, SHERRINGTON R, BRETT P, RIFKIN L, MURPHY P et al.(1993). Segregation and linkage analysis in five manic depression pedigrees excludes the 5HT1a receptor gene (HTR1A). Annals of Human Genetics vol. 57, (1) 27-39.
10.1111/j.1469-1809.1993.tb00884.x
Curtis D, Robertson MM, Gurling HMD(1992). Autosomal dominant gene transmission in a large kindred with Gilles de la Tourette Syndrome. British Journal of Psychiatry vol. 160, (JUNE) 845-849.
10.1192/bjp.160.6.845
Hatcher S, Bevan JS, Curtis D, Bullock T, Behan PO, Costa DC, Brostoff J, Douli V et al.(1992). Postviral fatigue syndrome [2]. British Medical Journal vol. 304, (6841) 1566-1567.
10.1136/bmj.304.6841.1566-b
Curtis D, Sham PC, Takei N, Murray RM, O'Callaghan E(1992). Schizophrenia following prenatal exposure to influenza epidemics between 1939 and 1960 [1]. British Journal of Psychiatry vol. 161, (NOV.) 712-714.
10.1192/bjp.161.5.712
Sherrington R, Melmer G, Dixon M, Curtis D, Mankoo B, Kalsi G, Gurling H(1991). Linkage disequilibrium between two highly polymorphic microsatellites. American Journal of Human Genetics vol. 49, (5) 966-971.
Holmes D, Brynjolfsson J, Brett P, Curtis D, Petursson H, Sherrington R, Gurling H(1991). No evidence for a susceptibility locus predisposing to manic depression in the region of the dopamine (D2) receptor gene. Br J Psychiatry vol. 158, 635-641.
10.1192/bjp.158.5.635
Mankoo BS, Sherrington R, De La Concha A, Kalsi G, Curtis D, Melmer G, Gurling HMD(1991). Two microsatellite polymorphisms at the D5S39 locus. Nucleic Acids Research vol. 19, (8)
10.1093/nar/19.8.1963-a
Brett P, Schneiden V, Jackson G, Curtis D, Gourdie A, Robertson M, Gurling H(1991). Chromosome markers in Tourette's syndrome. The Lancet vol. 337, (8734) 184-185.
10.1016/0140-6736(91)90857-L
Melmer G, Sherrington R, Mankoo B, Kalsi G, Curtis D, Gurling HMD(1991). A cosmid clone for the 5HT1A receptor (HTR1A) reveals a TaqI RFLP that shows tight linkage to DNA loci D5S6, D5S39, and D5S76. Genomics vol. 11, (3) 767-769.
10.1016/0888-7543(91)90088-V
Collinge J, Curtis D(1991). Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. British Journal of Psychiatry vol. 159, (DEC.) 857-859.
10.1192/bjp.159.6.857
Brett P, Curtis D, Melmer G, Sherrington R, Holmes D, Robertson M, Gurling H(1991). Lindage analysis in a large pedigree multiply affected with gilles de la tourette syndrome. Psychiatric Genetics vol. 1, (2) 26-28.
Holmes D, Brynjolfsson J, Brett P, Curtis D, Petursson H, Sherrington R, Gurling H(1991). No evidence for a susceptibility locus predisposing to manic depression in the region of the dopamine (D2) receptor gene. British Journal of Psychiatry vol. 158, (MAY) 635-641.
GURLING HMD, CURTIS D, MURRAY RM(1991). Psychological deficit from excessive alcohol consumption: evidence from a co‐twin control study. British Journal of Addiction vol. 86, (2) 151-155.
10.1111/j.1360-0443.1991.tb01765.x
Curtis D, Gurling HMD(1991). Using a dummy quantitative variable to deal with multiple affection categories in genetic linkage analysis. Annals of Human Genetics vol. 55, (4) 321-327.
10.1111/j.1469-1809.1991.tb00859.x
Brett P, Curtis D, Gourdie A, Schnieden V, Jackson G, Holmes D, Robertson M, Gurling H(1990). Possible linkage of Tourette syndrome to markers on short arm of chromosome 3 (C3p21-14). The Lancet vol. 336, (8722)
10.1016/0140-6736(90)92555-V
CURTIS D(1990). A program to draw pedigrees using LINKAGE or LINKSYS data files. Annals of Human Genetics vol. 54, (4) 365-367.
10.1111/j.1469-1809.1990.tb00390.x
Curtis D, Gurling H(1990). Unsound methodology in investigating a pseudoautosomal locus in schizophrenia. British Journal of Psychiatry vol. 156, (MAR.) 415-416.
10.1192/bjp.156.3.415
Gurling HMD, Sherrington RP, Brynjolfsson J, Read T, Curtis D, Mankoo BJ, Potter M, Petursson H(1989). Recent and future molecular genetic research into schizophrenia. Schizophrenia Bulletin vol. 15, (3) 373-382.
10.1093/schbul/15.3.373
Coleman RM, Curtis D(1989). Risk behaviours for HIV infection. BMJ (Clinical research ed.) vol. 298, (6686)
10.1136/bmj.298.6686.1522
COLEMAN RM, CURTIS D(1988). Distribution of Risk Behaviour for HIV Infection Amongst Intravenous Drug Users. British Journal of Addiction vol. 83, (11) 1331-1334.
10.1111/j.1360-0443.1988.tb03045.x
COLEMAN RM, CURTIS D, FEINMANN C(1988). Perception of Risk of HIV Infection by Injecting Drug Users and Effects on Medical Clinic Attendance. British Journal of Addiction vol. 83, (11) 1325-1329.
10.1111/j.1360-0443.1988.tb03044.x
Curtis D(1985). Recurrent pyoderma in a family with a defect in leucocyte locomotion. British Medical Journal (Clinical research ed.) vol. 290, (6467)
10.1136/bmj.290.6467.556-a
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