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Publications:  Dr Rathithevy Gangeswaran

Spurrell E, Gangeswaran R, Wang P, Cao F, Gao D, Feng B, Wold W, Tollefson A et al.(2017). Erratum: STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus [Journal of Virology, 88, 4, (2014) (2291-2300)] DOI: 10.1128/JVI.02829-13. Journal of Virology vol. 91, (20)
10.1128/JVI.00670-17
Spurrell E, Gangeswaran R, Wang P, Cao F, Gao D, Feng B, Wold W, Tollefson A et al.(2014). STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus. J Virol vol. 88, (4) 2291-2300.
10.1128/JVI.02829-13
Hiley CT, Chard LS, Gangeswaran R, Tysome JR, Briat A, Lemoine NR, Wang Y(2013). Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway. J Virol vol. 87, (5) 2781-2790.
10.1128/JVI.00854-12
Tysome JR, Li X, Wang S, Wang P, Gao D, Du P, Chen D, Gangeswaran R et al.(2012). A novel therapeutic regimen to eradicate established solid tumors with an effective induction of tumor-specific immunity. Clin Cancer Res vol. 18, (24) 6679-6689.
10.1158/1078-0432.CCR-12-0979
Wong HH, Jiang G, Gangeswaran R, Wang P, Wang J, Yuan M, Wang H, Bhakta V et al.(2012). Modification of the early gene enhancer-promoter improves the oncolytic potency of adenovirus 11. Mol Ther vol. 20, (2) 306-316.
10.1038/mt.2011.242
Tysome JR, Wang P, Alusi G, Briat A, Gangeswaran R, Wang J, Bhakta V, Fodor I et al.(2011). Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: an oncolytic virus superior to dl1520 (ONYX-015) for human head and neck cancer. Hum Gene Ther vol. 22, (9) 1101-1108.
10.1089/hum.2010.172
Wang Y, Gangeswaran R, Zhao X, Wang P, Tysome J, Bhakta V, Yuan M, Chikkanna-Gowda CP et al.(2009). CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells. J Clin Invest vol. 119, (6) 1604-1615.
10.1172/JCI37905
Wong HH, Gangeswaran R, Francis J, Lemoine NR, Wang Y (2009). Adenovirus 11 is an Alternative Oncolytic Virus Targeting Adenovirus 5-Insensitive Cancer and Shows Distinct E1A Gene Transcriptional Activity. MOLECULAR THERAPY. vol. 17, S235-S236.
Tysome JR, Briat A, Hiley C, Gangeswaran R, Chikkanna-Gowda CP, Bhakta V, Alusi G, Trivedi K et al. (2009). Systemic Delivery of Lister Strain Vaccinia Virus to Tumors Is Facilitated by the Depletion of Macrophages in Immuno-Competent Mice. MOLECULAR THERAPY. vol. 17, S247-S247.
Yuan M, Tomlinson V, Lara R, Holliday D, Chelala C, Harada T, Gangeswaran R, Manson-Bishop C et al.(2008). Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death Differ vol. 15, (11) 1752-1759.
10.1038/cdd.2008.108
Lopes RB, Gangeswaran R, McNeish IA, Wang Y, Lemoine NR(2007). Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy. Int J Cancer vol. 120, (11) 2344-2352.
10.1002/ijc.22554
Baril P, Gangeswaran R, Mahon PC, Caulee K, Kocher HM, Harada T, Zhu M, Kalthoff H et al.(2007). Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway. Oncogene vol. 26, (14) 2082-2094.
10.1038/sj.onc.1210009
Neesse A, Gangeswaran R, Luettges J, Feakins R, Weeks ME, Lemoine NR, Crnogorac-Jurcevic T(2007). Sperm-associated antigen 1 is expressed early in pancreatic tumorigenesis and promotes motility of cancer cells. Oncogene vol. 26, (11) 1533-1545.
10.1038/sj.onc.1209961
Harada T, Baril P, Gangeswaran R, Kelly G, Chelala C, Bhakta V, Caulee K, Mahon PC et al.(2007). Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation. Br J Cancer vol. 96, (2) 373-382.
10.1038/sj.bjc.6603563
Neesse A, Gangeswaran R, Luettges J, Feakins R, Weeks ME, Lemoine NR, Crnogorac-Jurcevic T(2006). Sperm associated antigen 1 (spag1) is expressed early in pancreatic tumorigenesis and promotes motility of cancer cells. PANCREAS vol. 33, (4) 485-486.
10.1097/00006676-200611000-00166
Crnogorac-Jurcevic T, Gangeswaran R, Bhakta V, Capurso G, Lattimore S, Akada M, Sunamura M, Prime W et al.(2005). Proteomic analysis of chronic pancreatitis and pancreatic adenocarcinoma. Gastroenterology vol. 129, (5) 1454-1463.
10.1053/j.gastro.2005.08.012
Dowen SE, Crnogorac-Jurcevic T, Gangeswaran R, Hansen M, Eloranta JJ, Bhakta V, Brentnall TA, Lüttges J et al.(2005). Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer. Am J Pathol vol. 166, (1) 81-92.
10.1016/S0002-9440(10)62234-1
Crnogorac-Jurcevic T, Missiaglia E, Blaveri E, Gangeswaran R, Jones M, Terris B, Costello E, Neoptolemos JP et al.(2003). Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalent. J Pathol vol. 201, (1) 63-74.
10.1002/path.1418
Santibáñez Koref MF, Gangeswaran R, Santibáñez Koref IP, Shanahan N, Hancock JM(2003). A phylogenetic approach to assessing the significance of missense mutations in disease genes. Hum Mutat vol. 22, (1) 51-58.
10.1002/humu.10235
Santibáñez-Koref MF, Gangeswaran R, Hancock JM(2001). A relationship between lengths of microsatellites and nearby substitution rates in mammalian genomes. Mol Biol Evol vol. 18, (11) 2119-2123.
10.1093/oxfordjournals.molbev.a003753
Santibanez MF, Gangeswaran R, Hancock JM(1999). CA repeat stimulated recombination: The role of mismatch repair in an E-coli model. AM J HUM GENET vol. 65, (4) A320-A320.
Parrington J, Brind S, De Smedt H, Gangeswaran R, Lai FA, Wojcikiewicz R, Carroll J(1998). Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization. Dev Biol vol. 203, (2) 451-461.
10.1006/dbio.1998.9071
Gangeswaran R, Jones KT(1997). Unique protein kinase C profile in mouse oocytes: lack of calcium-dependent conventional isoforms suggested by rtPCR and Western blotting. FEBS Lett vol. 412, (2) 309-312.
10.1016/s0014-5793(97)00782-5
Gangeswaran R, Eady RR(1996). Flavodoxin 1 of Azotobacter vinelandii: characterization and role in electron donation to purified assimilatory nitrate reductase. Biochem J vol. 317 ( Pt 1), 103-108.
10.1042/bj3170103
Gangeswaran R, Lowe DJ, Eady RR(1993). Purification and characterization of the assimilatory nitrate reductase of Azotobacter vinelandii. Biochem J vol. 289 ( Pt 2), 335-342.
10.1042/bj2890335
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