Publications: Prof Chloe Orkin
Orkin C, DeJesus E, Sax PE, Arribas JR, Gupta SK, Martorell C, Stephens JL, Stellbrink HJ et al.(2020).
Fixed-dose combination bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir-containing regimens for initial treatment of HIV-1 infection: week 144 results from two randomised, double-blind, multicentre, phase 3, non-inferiority trials. The Lancet HIV
vol. 7,
(6)
e389-e400.
Wan Y, Apea V, Dhairyawan R, Orkin C, Pearse RM, Prowle JR (2020).
ETHICAL: Ethnic Disparities In COVID-19 Admissions in east London.
Stirrup OT, Asboe D, Pozniak A, Sabin CA, Gilson R, Mackie NE, Tostevin A, Hill T et al.(2020).
Continuation of emtricitabine/lamivudine within combination antiretroviral therapy following detection of the M184V/I HIV-1 resistance mutation. HIV Medicine
vol. 21,
(5)
309-321.
Orkin C, Goddard SL(2020).
Enrolling pregnant women with HIV into clinical trials. The Lancet HIV
vol. 7,
(5)
e302-e303.
Orkin C, Eron JJ, Rockstroh J, Podzamczer D, Esser S, Vandekerckhove L, Van Landuyt E, Lathouwers E et al.(2020).
Week 96 results of a phase 3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients. AIDS (London, England)
vol. 34,
(5)
707-718.
Garvey LJ, Cooke GS, Smith C, Stingone C, Ghosh I, Dakshina S, Jain L, Waters LJ et al.(2020).
Decline in Hepatitis C Virus (HCV) Incidence in Men Who Have Sex With Men Living With Human Immunodeficiency Virus: Progress to HCV Microelimination in the United Kingdom?. Clin Infect Dis
Thompson M, Orkin C, Molina JM, Sax P, Cahn P, Squires K, Xu X, Rodgers A et al.(2020).
Once-daily doravirine for initial treatment of adults living with human immunodeficiency virus-1: An integrated safety analysis. Clinical Infectious Diseases
vol. 70,
(7)
1336-1343.
Orkin C, Molina JM, Lombaard J, Dejesus E, Rodgers A, Kumar S, Martin E, Hanna G et al.(2020).
Once-daily doravirine in human immunodeficiency virus type 1-infected, antiretroviral-naive adults: An integrated efficacy analysis. Clinical Infectious Diseases
vol. 70,
(7)
1344-1352.
Orkin C, Arasteh K, Górgolas Hernández-Mora M, Pokrovsky V, Overton ET, Girard PM, Oka S, Walmsley S et al.(2020).
Long-acting cabotegravir and rilpivirine after oral induction for HIV-1 infection. New England Journal of Medicine
vol. 382,
(12)
1124-1135.
Orkin C, Molina JM, Lombaard(2020).
Erratum: Oncedaily doravirine in human immunodeficiency virus type 1-infected, antiretroviral-naive adults: An integrated efficacy analysis (Clinical Infectious Diseases DOI: 10.1093/cid/ciz424). Clinical Infectious Diseases
vol. 70,
(2)
Gupta N, Gilleece Y, Orkin C(2020).
Implementing U=U in clinical practice: Results of a British HIV association members survey. Sexually Transmitted Infections
Cevik M, Orkin C(2019).
Insights into HIV-1 capsid inhibitors in preclinical and early clinical development as antiretroviral agents. Expert Opinion on Investigational Drugs
vol. 28,
(12)
1021-1024.
Lampe FC, Rodger AJ, Burman W, Grulich A, Friedland G, Sadr WE, Neaton J, Corbelli GM et al.(2019).
Impact of early antiretroviral treatment on sexual behaviour: A randomised comparison. AIDS
vol. 33,
(15)
2337-2350.
Lampe FC, Rodger AJ, Burman W, Grulich A, Friedland G, Sadr WE, Neaton J, Corbelli GM et al.(2019).
Impact of early antiretroviral treatment on sexual behaviour: a randomised comparison. AIDS
vol. 33,
(15)
2337-2350.
Martin EA, Hwang C, Orkin C(2019).
Reply to Lanzafame et al. Clinical Infectious Diseases
vol. 69,
(10)
1832-1833.
Quercia R, Orkin C, D'Amico R, Mrus J, Wu S, Cutrell A, Chow K, Polli J et al. (2019).
EACS 2019-Abstract Book. HIV MEDICINE.
vol. 20,
3-3.
Orkin C, Elion R, Thompson M, Rockstroh J, Xu ZJ, Martin EA, Hwang C, Sklar P et al. (2019).
Effect of doravirine on body weight and body mass index in treatment naive adults with HIV-1. HIV MEDICINE.
vol. 20,
7-8.
Orkin C, Kityo C, Koenig E, Natukunda E, Ajana F, Gandhi-Patel B, Liu Y, Wei L et al. (2019).
Efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide vs comparators in cis-women and girls (living with HIV): an analysis of 5 clinical trials. HIV MEDICINE.
vol. 20,
22-22.
Orkin C, Sax PE, Arribas J, Gupta S, Martorell C, Stephens JL, Stellbrink H-J, Dejesus E et al. (2019).
Long-term efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in ART-naive adults. HIV MEDICINE.
vol. 20,
94-95.
Stellbrink H-J, Post FA, Podzamczer D, Arribas J, Cua E, Molina J-M, Orkin C, Rockstroh JK et al. (2019).
Safety and efficacy of switching from tenofovir disoproxil fumarate to tenofovir alafenamide in people with HIV aged 50 years and older. HIV MEDICINE.
vol. 20,
138-138.
Sax PE, Erlandson KM, Lake JE, McComsey GA, Orkin C, Esser S, Brown TT, Rockstroh JK et al.(2019).
Weight Gain Following Initiation of Antiretroviral Therapy: Risk Factors in Randomized Comparative Clinical Trials. Clin Infect Dis
Eron JJ, Orkin C, Cunningham D, Pulido F, Post FA, De Wit S, Lathouwers E, Hufkens V et al.(2019).
Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1. Antiviral Research
vol. 170,
Mbisa JL, Kirwan P, Tostevin A, Ledesma J, Bibby DF, Brown A, Myers R, Hassan AS et al.(2019).
Determining the Origins of Human Immunodeficiency Virus Type 1 Drug-resistant Minority Variants in People Who Are Recently Infected Using Phylogenetic Reconstruction. Clin Infect Dis
vol. 69,
(7)
1136-1143.
Aboud M, Orkin C, Podzamczer D, Bogner JR, Baker D, Khuong-Josses MA, Parks D, Angelis K et al.(2019).
Efficacy and safety of dolutegravir–rilpivirine for maintenance of virological suppression in adults with HIV-1: 100-week data from the randomised, open-label, phase 3 SWORD-1 and SWORD-2 studies. The Lancet HIV
vol. 6,
(9)
e576-e587.
Huhn GD, Eron JJ, Girard PM, Orkin C, Molina JM, Dejesus E, Petrovic R, Luo D et al.(2019).
Darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-experienced, virologically suppressed patients with HIV-1: Subgroup analyses of the phase 3 EMERALD study. AIDS Research and Therapy
vol. 16,
(1)
Gupta SK, Post FA, Arribas JR, Eron JJ, Wohl DA, Clarke AE, Sax PE, Stellbrink HJ et al.(2019).
Renal safety of tenofovir alafenamide vs. tenofovir disoproxil fumarate: A pooled analysis of 26 clinical trials. AIDS
vol. 33,
(9)
1455-1465.
Bundle N, Balasegaram S, Parry S, Ullah S, Harris RJ, Ahmad K, Foster GR, Tong CYW et al.(2019).
Seroprevalence and demographic factors associated with hepatitis B, hepatitis C and HIV infection from a hospital emergency department testing programme, London, United Kingdom, 2015 to 2016. Eurosurveillance
vol. 24,
(27)
Orkin C(2019).
Does less equal more yet?. The Lancet HIV
vol. 6,
(7)
e412-e413.
Cullen L, Grenfell P, Rodger A, Orkin C, Mandal S, Rhodes T(2019).
'Just another vial': A qualitative study to explore the acceptability and feasibility of routine blood-borne virus testing in an emergency department setting in the UK. BMJ Open
vol. 9,
(4)
Podzamczer D, Stellbrink H-J, Orkin C, Pozniak A, Arribas J, Koenig E, Ramgopal M, Baumgarten A et al. (2019).
B/F/TAF versus ABC/DTG/3TC or DTG + F/TAF in treatment-naive adults with high baseline viral load or low baseline CD4 cell count: week 96 results. HIV MEDICINE.
vol. 20,
18-18.
Van Wyk J, Orkin C, Rubio-Garcia R, Bogner J, Baker D, Khuong-Josses M-A, Parks D, Angelis K et al. (2019).
Durable suppression and low rate of virological failures 3 years after switch to DTG plus RPV two-drug regimen: SWORD 1 and 2 studies. HIV MEDICINE.
vol. 20,
18-19.
Amele S, Peters L, Sluzhynska M, Yakovlev A, Scherrer A, Domingo P, Gerstoft J, Viard JP et al.(2019).
Establishing a hepatitis C continuum of care among HIV/hepatitis C virus-coinfected individuals in EuroSIDA. HIV Medicine
vol. 20,
(4)
264-273.
Orkin C, Arasteh K, Hernandez-Mora MG, Pokrovsky V, Overton ET, Girard P-M, Oka S, D'Amico R et al. (2019).
Long-active cabotegravir plus rilpivirine for HIV maintenance: FLAIR week-48 results. HIV MEDICINE.
vol. 20,
6-7.
Martinello M, Orkin C, Cooke G, Bhagani S, Gane E, Kulasegaram R, Shaw D, Tu E et al. (2019).
Shortened duration pan-genotypic therapy with glecaprevir-pibrentasvir for six weeks among people with acute and recent HCV infection. JOURNAL OF HEPATOLOGY.
vol. 70,
E231-E231.
Orkin C, Squires KE, Molina JM, Sax PE, Wong WW, Sussmann O, Kaplan R, Lupinacci L et al.(2019).
Doravirine/Lamivudine/Tenofovir disoproxil fumarate is non-inferior to efavirenz/emtricitabine/tenofovir disoproxil fumarate in treatment-naive adults with human immunodeficiency virus-1 infection: Week 48 results of the DRIVE-AHEAD Trial. Clinical Infectious Diseases
vol. 68,
(4)
535-544.
Finnerty F, Azad Y, Orkin C(2019).
Hostile health-care environment could increase migrants' risk of HIV and prevent access to vital services. The Lancet HIV
vol. 6,
(2)
Gatell JM, Assoumou L, Moyle G, Waters L, Johnson M, Domingo P, Fox J, Martinez E et al.(2019).
Immediate versus deferred switching from a boosted protease inhibitor-based regimen to a dolutegravir-based regimen in virologically suppressed patients with high cardiovascular risk or age ≥50 years: Final 96-week results of the NEAT022 study. Clinical Infectious Diseases
vol. 68,
(4)
597-606.
Cahn P, Madero JS, Arribas JR, Antinori A, Ortiz R, Clarke AE, Hung CC, Rockstroh JK et al.(2019).
Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2): week 48 results from two multicentre, double-blind, randomised, non-inferiority, phase 3 trials. The Lancet
vol. 393,
(10167)
143-155.
Martinello M, Orkin C, Cooke G, Bhagani S, Gane E, Kulasegaram R, Shaw D, Tu E et al.(2019).
Short-Duration Pan-Genotypic Therapy With Glecaprevir/Pibrentasvir for 6 Weeks Among People With Recent Hepatitis C Viral Infection. Hepatology
Geretti AM, White E, Orkin C, Tostevin A, Tilston P, Chadwick D, Leen C, Sabin C et al.(2019).
Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance. Journal of Antimicrobial Chemotherapy
vol. 74,
(3)
746-753.
Hagins D, Orkin C, Daar ES, Mills A, Brinson C, DeJesus E, Post FA, Morales-Ramirez J et al.(2018).
Switching to coformulated rilpivirine (RPV), emtricitabine (FTC) and tenofovir alafenamide from either RPV, FTC and tenofovir disoproxil fumarate (TDF) or efavirenz, FTC and TDF: 96-week results from two randomized clinical trials. HIV Medicine
vol. 19,
(10)
724-733.
Podzamczer D, Stellbrink H, Orkin C, Pozniak A, Arribas J, Koenig E, Ramgopal M, Baumgarten A et al. (2018).
B/F/TAF versus ABC/DTG/3TC or DTG + F/TAF in treatment-naive adults with high baseline viral load or low baseline CD4 count in two Phase III randomized, controlled clinical trials: Week 96 results. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY.
vol. 21,
Orkin C, Eron J, Rockstroh J, Podzamczer D, Esser S, Vandekerckhove L, Van Landuyt E, Lathouwers E et al. (2018).
Efficacy and safety of the once-daily, darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) single-tablet regimen (STR) in ART-naive, HIV-1-infected adults: AMBER Week 96 results. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY.
vol. 21,
Orkin C, Lampe F, Izambert C, Waters L (2018).
Mental health and HIV: what we all need to know. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY.
vol. 21,
Martinello M, Bhagani S, Gane E, Orkin C, Cooke G, Dore GJ, Petoumenos K, Applegate TL et al.(2018).
Shortened therapy of eight weeks with paritaprevir/ritonavir/ombitasvir and dasabuvir is highly effective in people with recent HCV genotype 1 infection. Journal of Viral Hepatitis
vol. 25,
(10)
1180-1188.
Orkin C, Porteiro N, Berhe M, Dretler R, Viciana P, Tseng Y, Oprea C, Johnson M et al. (2018).
Two-drug regimen of dolutegravir plus lamivudine (DTG+3TC) is non-inferior to dolutegravir plus tenofovir/emtricitabine (DTG plus TDF/FTC) at 48 weeks in antiretroviral treatment-naive adults with HIV-1 infection: subgroup analyses in the GEMINI studies. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY.
vol. 21,
Rockstroh JK, Lacombe K, Viani RM, Orkin C, Wyles D, Luetkemeyer AF, Soto-Malave R, Flisiak R et al.(2018).
Efficacy and Safety of Glecaprevir/Pibrentasvir in Patients Coinfected with Hepatitis C Virus and Human Immunodeficiency Virus Type 1: The EXPEDITION-2 Study. Clinical Infectious Diseases
vol. 67,
(7)
1010-1017.
Cresswell FV, Ellis J, Hartley J, Sabin CA, Orkin C, Churchill DR(2018).
A systematic review of risk of HIV transmission through biting or spitting: implications for policy. HIV Medicine
vol. 19,
(8)
532-540.
Eron JJ, Orkin C, Gallant J, Molina JM, Negredo E, Antinori A, Mills A, Reynes J et al.(2018).
A week-48 randomized phase-3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients. AIDS
vol. 32,
(11)
1431-1442.
Cevik M, Orkin C(2018).
Fixed dose darunavir boosted with cobicistat combined with emtricitabine and tenofovir alafenamide fumarate. Current Opinion in HIV and AIDS
vol. 13,
(4)
315-319.
Psomas C, Kinloch S, Sabin C, Soriano V, Solas C, Orkin C, Bernardino J, Curran A et al.(2018).
Highlights from the 20th International Symposium on HIV and Emerging Infectious Diseases (ISHEID) 16-18 May 2018, Marseille, France: from HIV and comorbidities to global health. J Virus Erad
vol. 4,
(3)
196-207.
Jose S, Delpech V, Howarth A, Burns F, Hill T, Porter K, Sabin CA, Ainsworth J et al.(2018).
A continuum of HIV care describing mortality and loss to follow-up: a longitudinal cohort study. The Lancet HIV
vol. 5,
(6)
e301-e308.
Parry S, Bundle N, Ullah S, Foster GR, Ahmad K, Tong CYW, Balasegaram S, Orkin C(2018).
Implementing routine blood-borne virus testing for HCV, HBV and HIV at a London Emergency Department-uncovering the iceberg?. Epidemiology and Infection
vol. 146,
(8)
1026-1035.
Santos JR, Cozzi-Lepri A, Phillips A, De Wit S, Pedersen C, Reiss P, Blaxhult A, Lazzarin A et al.(2018).
Long-term effectiveness of recommended boosted protease inhibitor-based antiretroviral therapy in Europe. HIV Medicine
vol. 19,
(5)
324-338.
Volz EM, Le Vu S, Ratmann O, Tostevin A, Dunn D, Orkin C, O'Shea S, Delpech V et al.(2018).
Molecular Epidemiology of HIV-1 Subtype B Reveals Heterogeneous Transmission Risk: Implications for Intervention and Control. Journal of Infectious Diseases
vol. 217,
(10)
1522-1529.
Stirrup OT, Dunn DT, Tostevin A, Sabin CA, Pozniak A, Asboe D, Cox A, Orkin C et al.(2018).
Risk factors and outcomes for the Q151M and T69 insertion HIV-1 resistance mutations in historic UK data. AIDS Research and Therapy
vol. 15,
(1)
Cresswell F, Ellis J, Hartley J, Sabin C, Brook G, Orkin C, Churchill D (2018).
A systematic review of risk of HIV transmission through biting or spitting: implications for policy. HIV MEDICINE.
vol. 19,
S43-S43.
Roen A, Laut K, Pelchen-Matthews A, Borodulina E, Caldeira L, Clarke A, Clotet B, d'Arminio Monforte A et al.(2018).
Abacavir usage patterns and hypersensitivity reactions in the EuroSIDA cohort. HIV Medicine
vol. 19,
(4)
252-260.
Orkin C, Libre J, Kahl L, Blair E, Wynne B, Curtis L, Angelis K, Shah R et al. (2018).
Renal, Inflammatory and bone biomarkers following switch to the DTG + RPV 2-drug regimen: the SWORD-1 and SWORD-2 studies. HIV MEDICINE.
vol. 19,
S17-S17.
Orkin C, Khuong-Josses M-A, Lutz T, Baker D, Rubio R, Blair E, Kahl L, Angelis K et al. (2018).
Safety and efficacy of DTG plus RPV in the phase III SWORD-1 and SWORD-2 studies: 48-week subgroup analysis by baseline third agent class and geographic location. HIV MEDICINE.
vol. 19,
S28-S29.
Cozzi-Lepri A, Zangerle R, Machala L, Zilmer K, Ristola M, Pradier C, Kirk O, Sambatakou H et al.(2018).
Incidence of cancer and overall risk of mortality in individuals treated with raltegravir-based and non-raltegravir-based combination antiretroviral therapy regimens. HIV Medicine
vol. 19,
(2)
102-117.
Shepherd L, Borges H, Harvey R, Bower M, Grulich A, Silverberg M, Weber J, Ristola M et al.(2018).
The extent of B-cell activation and dysfunction preceding lymphoma development in HIV-positive people. HIV Medicine
vol. 19,
(2)
90-101.
Jose S, Hamzah L, Jones R, Williams D, Winston A, Burns F, Phillips AN, Sabin CA et al.(2018).
Chronic kidney disease risk in African and Caribbean populations with HIV. Journal of Infectious Diseases
vol. 218,
(11)
1767-1772.
Orkin C, Molina JM, Negredo E, Arribas JR, Gathe J, Eron JJ, Van Landuyt E, Lathouwers E et al.(2018).
Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial. The Lancet HIV
vol. 5,
(1)
e23-e34.
Orkin C, Llibre JM, Gallien S, Antinori A, Behrens GMN, Carr A(2018).
Nucleoside reverse transcriptase inhibitor-reducing strategies in HIV treatment: assessing the evidence. HIV Medicine
vol. 19,
(1)
18-32.
Peters L, Mocroft A, Grint D, Moreno S, Calmy A, Jevtovic D, Sambatakou H, Lacombe K et al.(2018).
Uptake of tenofovir-based antiretroviral therapy among HIV-HBV-coinfected patients in the EuroSIDA study. Antiviral Therapy
vol. 23,
(5)
405-413.
Orrell C, Hagins DP, Belonosova E, Porteiro N, Walmsley S, Falcó V, Man CY, Aylott A et al.(2017).
Fixed-dose combination dolutegravir, abacavir, and lamivudine versus ritonavir-boosted atazanavir plus tenofovir disoproxil fumarate and emtricitabine in previously untreated women with HIV-1 infection (ARIA): week 48 results from a randomised, open-label, non-inferiority, phase 3b study. The Lancet HIV
vol. 4,
(12)
e536-e546.
Gallant J, Lazzarin A, Mills A, Orkin C, Podzamczer D, Tebas P, Girard PM, Brar I et al.(2017).
Bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection (GS-US-380-1489): a double-blind, multicentre, phase 3, randomised controlled non-inferiority trial. The Lancet
vol. 390,
(10107)
2063-2072.
Patterson S, Jose S, Samji H, Cescon A, Ding E, Zhu J, Anderson J, Burchell AN et al.(2017).
A tale of two countries: all-cause mortality among people living with HIV and receiving combination antiretroviral therapy in the UK and Canada. HIV Medicine
vol. 18,
(9)
655-666.
Martinello M, Bhagani S, Gane EJ, Orkin C, Cooke G, Kulasegaram R, Shaw D, Hellard M et al. (2017).
Shortened therapy of 8 weeks duration with paritaprevir/ritonavir/ombitasvir and dasabuvir is highly effective in people with acute and recent genotype 1 HCV infection: The TARGET3D Study. HEPATOLOGY.
vol. 66,
574A-575A.
Gourlay A, Fox J, Gafos M, Fidler S, Nwokolo N, Clarke A, Gilson R, Orkin C et al.(2017).
A qualitative study exploring the social and environmental context of recently acquired HIV infection among men who have sex with men in South-East England. BMJ Open
vol. 7,
(8)
Pasvol TJ, Orkin C(2017).
Few men who have sex with men (MSM) attending two inner-city clinics were tested for hepatitis C virus (HCV) despite high risk: A retrospective analysis of sexual health screening in East London. Sexually Transmitted Infections
vol. 93,
(5)
Gallant J, Lazzarin A, Mills A, Orkin C, Podzamczer D, Tebas P, Girard P-M, Brar I et al. (2017).
A Phase 3 randomized controlled clinical trial of bictegravir in a fixed dose combination, B/F/TAF, vs ABC/DTG/3TC in treatment-naive adults at Week 48. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY.
vol. 20,
103-104.
Smit E, White E, Clark D, Churchill D, Zhang H, Collins S, Pillay D, Sabin C et al.(2017).
An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs. Journal of Antimicrobial Chemotherapy
vol. 72,
(7)
2075-2082.
O'Connor J, Smith C, Lampe FC, Johnson MA, Chadwick DR, Nelson M, Dunn D, Winston A et al.(2017).
Durability of viral suppression with first-line antiretroviral therapy in patients with HIV in the UK: an observational cohort study. The Lancet HIV
vol. 4,
(7)
e295-e302.
Raffi F, Orkin C, Clarke A, Slama L, Gallant J, Daar E, Henry K, Santana-Bagur J et al. (2017).
Brief Report: Long-Term (96-Week) Efficacy and Safety after Switching from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in HIV-Infected, Virologically Suppressed Adults. Journal of Acquired Immune Deficiency Syndromes.
vol. 75,
226-231.
Borges ÁH, Hoy J, Florence E, Sedlacek D, Stellbrink HJ, Uzdaviniene V, Tomazic J, Gargalianos-Kakolyris P et al.(2017).
Antiretrovirals, Fractures, and Osteonecrosis in a Large International HIV Cohort. Clinical Infectious Diseases
vol. 64,
(10)
1413-1421.
Orkin C, DeJesus E, Ramgopal M, Crofoot G, Ruane P, LaMarca A, Mills A, Vandercam B et al.(2017).
Switching from tenofovir disoproxil fumarate to tenofovir alafenamide coformulated with rilpivirine and emtricitabine in virally suppressed adults with HIV-1 infection: a randomised, double-blind, multicentre, phase 3b, non-inferiority study. The Lancet HIV
vol. 4,
(5)
e195-e204.
Howarth AR, Burns FM, Apea V, Jose S, Hill T, Delpech VC, Evans A, Mercer CH et al.(2017).
Development and application of a new measure of engagement in out-patient HIV care. HIV Medicine
vol. 18,
(4)
267-274.
McNulty M, Orkin C, Smith C, Marshall N, Swaden L, Burns F (2017).
Real-life experience of switching to protease inhibitor-based dual antiretroviral therapy (PIDAT). HIV MEDICINE.
vol. 18,
17-18.
Orkin C, DeJesus E, Ramgopal M, Crofoot G, Ruane P, LaMarca A, Mills A, Van der Cam B et al. (2017).
Switching from efavirenz/emtricitabine/tenofovir (EFV/FTC/TDF) or rilpivirine/emtricitabine/tenofovir disoproxil fumarate (RPV/FTC/TDF) to rilpivirine/emtricitabine/tenofovir alafenamide (RPV/FTC/TAF): safety and efficacy through 48 weeks. HIV MEDICINE.
vol. 18,
21-21.
Tostevin A, White E, Dunn D, Croxford S, Delpech V, Williams I, Asboe D, Pozniak A et al.(2017).
Recent trends and patterns in HIV-1 transmitted drug resistance in the United Kingdom. HIV Medicine
vol. 18,
(3)
204-213.
Stöhr W, Dunn DT, Arenas-Pinto A, Orkin C, Clarke A, Williams I, Johnsone M, Beeching NJ et al.(2016).
Factors associated with virological rebound in HIV-infected patients receiving protease inhibitor monotherapy. AIDS
vol. 30,
(17)
2617-2624.
Dhairyawan R, O'Connell R, Flanagan S, Wallis E, Orkin C(2016).
Linkage to care after routine HIV, hepatitis B & C testing in the emergency department: The 'Going Viral' campaign. Sexually Transmitted Infections
vol. 92,
(7)
Barr E, Rockstroh JK, Nelson M, Katlama C, Lalezari J, Mallolas J, Bloch M, Matthews G et al. (2016).
High efficacy of elbasvir/grazoprevir (EBR/GZR) in HCV genotype 1, 4, and 6-infected patients with HIV coinfection: SVR24 data from the phase 3 C-EDGE Coinfection study. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY.
vol. 31,
66-66.
Raffi F, Orkin C, Clarke A, Slama L, Gallant J, Daar E, Yan M, Abram ME et al. (2016).
Long-term (96-week) efficacy and safety after switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) in HIV-infected, virologically suppressed adults. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY.
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