Publications: Dr Magdalena Flak
Hosomi S, Grootjans J, Tschurtschenthaler M, Krupka N, Matute JD, Flak MB, Martinez-Naves E, Gomez Del Moral M et al.(2017).
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation. J Exp Med
vol. 214,
(10)
2985-2997.
Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB et al.(2017).
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis. J Exp Med
vol. 214,
(2)
401-422.
Wright RD, Souza PR, Flak MB, Thedchanamoorthy P, Norling LV, Cooper D(2016).
Galectin-3-null mice display defective neutrophil clearance during acute inflammation. J Leukoc Biol
Baker K, Rath T, Flak MB, Arthur JC, Chen Z, Glickman JN, Zlobec I, Karamitopoulou E et al.(2013).
Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer. Immunity
vol. 39,
(6)
1095-1107.
Adolph TE, Tomczak MF, Niederreiter L, Ko H-J, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M et al.(2013).
Paneth cells as a site of origin for intestinal inflammation. Nature
vol. 503,
(7475)
272-276.
Niederreiter L, Fritz TMJ, Adolph TE, Krismer A-M, Offner FA, Tschurtschenthaler M, Flak MB, Hosomi S et al.(2013).
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells. J Exp Med
vol. 210,
(10)
2041-2056.
Flak MB, Neves JF, Blumberg RS(2013).
Immunology. Welcome to the microgenderome. Science
vol. 339,
(6123)
1044-1045.
Archibald KM, Kulbe H, Kwong J, Chakravarty P, Temple J, Chaplin T, Flak MB, McNeish IA et al.(2012).
Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium. Oncogene
vol. 31,
(48)
4987-4995.
Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, Gerber G, Huang Y-H et al.(2012).
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction. Immunity
vol. 37,
(5)
930-946.
Tomczak M, Ko H-J, Adolph T, Flak MB, Martinez-Naves E, Hosomi S, Glickman J, Kaser A et al. (2012).
Impaired Autophagy Promotes ER Stress Induced Intestinal Inflammation. GASTROENTEROLOGY.
vol. 142,
S124-S125.
Kaser A, Flak MB, Tomczak MF, Blumberg RS(2011).
The unfolded protein response and its role in intestinal homeostasis and inflammation. Exp Cell Res
vol. 317,
(19)
2772-2779.
Connell CM, Shibata A, Tookman L, Archibald KM, Flak MB, Pirlo KJ, Lockley M, Wheatley SP et al.(2011).
Genomic DNA damage and ATR-Chk1 signalling determine adenovirus oncolytic efficacy in ovarian cancer. HUMAN GENE THERAPY
vol. 22,
(10)
A113-A113.
Connell CM, Shibata A, Tookman LA, Archibald KM, Flak MB, Pirlo KJ, Lockley M, Wheatley SP et al.(2011).
Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells. J Clin Invest
vol. 121,
(4)
1283-1297.
Flak MB, Connell CM, Chelala C, Archibald K, Salako MA, Pirlo KJ, Lockley M, Wheatley SP et al.(2010).
p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker. Mol Cancer
vol. 9,
Coughlan L, Vallath S, Saha A, Flak M, McNeish IA, Vassaux G, Marshall JF, Hart IR et al.(2009).
In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery. J Virol
vol. 83,
(13)
6416-6428.
Flak MB, Connell CM, Hill RM, Hallden G, Chelala C, McNeish IA (2009).
Critical Role for p21 and p27 in Efficacy of Oncolytic Adenovirus dl922-947 in Ovarian Cancer. MOLECULAR THERAPY.
vol. 17,
S100-S100.
Flak MB, Connell CM, Hill RM, Hallden G, Chelala C, McNeish IA (2008).
Host cell factors in ovarian cancer influencing efficacy of oncolytic adenovirus dl922-947. HUMAN GENE THERAPY.
vol. 19,
1083-1083.
