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Publications:  Dr Egle Solito

Sheikh MH, Henson S, Loiola RA, Mercurio S, Colamatteo A, Maniscalco GT, De Rosa V, Mcarthur S et al.(2020). Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier. Journal of Neuroinflammation
10.1186/s12974-020-01810-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64712
Callender L, Carroll E, BOBER E, Akbar A, Solito E, Henson S(2019). Mitochondrial mass governs the extent of human T cell senescence. Aging Cell vol. 19, (2)
10.1111/acel.13067
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63820
Solito E, Montague-Cardoso, K, Pitcher T, Chisolm K, Salera G, Lindstrom E, Hewitt E, Malcangio M(2019). Changes in vascular permeability in the spinal cord contribute to chemotherapy- induced neuropathic pain. Brain Behaviour and Immunity
10.1016/j.bbi.2019.10.018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63920
Solito E, Zub E, Canet G, Garbelli R, Blaquiere M, Rossini L, Pastori C, Sheikh M et al.(2019). The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy. The FASEB Journal
10.1096/fj.201901596R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61502
Solito E, Colamatteo A, Maggioli E, Azevedo Loiola R, Sheikh M, Cali G, Bruzzese D, Maniscalco T et al.(2019). Reduced Annexin A1 expression associates with disease severity and inflammation in multiple sclerosis patients. Journal of Immunology
10.4049/jimmunol.1801683
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60019
da Rocha GHO, Loiola RA, Pantaleão LDN, Reutelingsperger C, Solito E, Farsky SHP(2019). Control of expression and activity of peroxisome proliferated-activated receptor γ by Annexin A1 on microglia during efferocytosis. Cell Biochemistry and Function
10.1002/cbf.3433
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60901
Pickering J, Ries M, Solito E, Semmler A, Sastre M (2019). Administration of annexin-A1 reduces tau phosphorylation in the tau-P301L mouse model. BRITISH JOURNAL OF PHARMACOLOGY. vol. 176, 3024-3024.
Loiola RA, Wickstead ES, Solito E, Mcarthur S(2019). Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Frontiers in Endocrinology
10.3389/fendo.2019.00420
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58286
SOLITO EGLE, PURVIS G, THIEMERMANN C(2019). Annexin-A1: therapeutic potential in microvascular disease. Frontiers in Immunology
10.3389/fimmu.2019.00938
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57697
Loiola RA, Wickstead ES, Solito E, McArthur S(2019). Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Front Endocrinol (Lausanne) vol. 10,
10.3389/fendo.2019.00420
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59871
Purvis GSD, Collino M, Loiola RA, Baragetti A, Chiazza F, Brovelli M, Sheikh MH, Collotta D et al.(2019). Identification of Annexina1 as an endogenous regulator of RhoA, and its role in the pathophysiology and experimental therapy of type-2 diabetes. Frontiers in Immunology vol. 10, (MAR)
10.3389/fimmu.2019.00571
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58923
SOLITO E(2018). Connections of Annexin A1 and Translocator Protein-18 KDa on Toll Like Receptor Stimulated BV-2 Cells. Exp Cell Res.
10.1016/j.yexcr.2018.04.008
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56720
SOLITO E, SHEIKH M(2018). Annexin A1: Uncovering the Many Talents of an Old Protein. International Journal of Molecular Sciences vol. 19,
10.3390/ijms19041045
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36463
Purvis GSD, Chiazza F, Chen J, Loiola RA, Martin L, Fountoulakis N, Gnudi L, Collino M et al.(2017). Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes. Diabetologia
10.1007/s00125-017-4469-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28601
Lima KM, Vago JP, Caux TR, Negreiros-Lima GL, Sugimoto MA, Tavares LP, Arribada RG, Carmo AAF et al.(2017). The resolution of acute inflammation induced by cyclic AMP is dependent on Annexin A1. Journal of Biological Chemistry vol. 292, (33) 13758-13773.
10.1074/jbc.M117.800391
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25053
Purvis GSD, Chiazza F, Collino M, Solito E, Thiemermann C (2017). Endogenous Annexin-A1 is a Protective Determinant in HFD-induced Insulin Resistance and Diabetic Nephropathy. FASEB JOURNAL. Conference: FASEB vol. 31,
Purvis GSD, Chiazza F, Solito E, Collino M, Thiemermann C (2017). Endogenous annexin-A1 is a protective determinant in high-fat diet (HFD)-induced insulin resistance and diabetic nephropathy. DIABETIC MEDICINE. Conference: European Shock Society vol. 34, 26-26.
10.1111/dme.42_13304
Purvis GSD, Loiola RA, Keswich J, Theimermann C, Solito E (2017). Role of annexin-A1 on blood-brain barrier functionality. DIABETIC MEDICINE. vol. 34, 64-64.
McArthur S, Loiola RA, Maggioli, E, Errede M, Virgintino D, SOLITO E(2016). The restorative role of annexin A1 at the blood–brain barrier. Fluids and Barriers of the CNS vol. 13, (17)
10.1186/s12987-016-0043-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16229
SOLITO E, Loiola R, Ries M, Shah U, Gentleamn S, Sastre M(2016). The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide. Journal of Neuroinflammation vol. 13,
10.1186/s12974-016-0692-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14989
Sinniah A, Yazid S, Perretti M, Solito E, Flower RJ(2016). The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil. International Immunopharmacology vol. 32, 87-95.
10.1016/j.intimp.2016.01.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13482
Maggioli E, McArthur S, Mauro C, Kieswich J, Kusters DHM, Reutelingsperger CPM, Yaqoob M, Solito E(2016). Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking. Brain, Behavior, and Immunity vol. 51, 212-222.
10.1016/j.bbi.2015.08.020
https://qmro.qmul.ac.uk/xmlui/handle/123456789/8781
Yazid S, Gardner PJ, Carvalho L, Chu CJ, Flower RJ, Solito E, Lee RWJ, Ali RR et al.(2015). Annexin-A1 restricts Th17 cells and attenuates the severity of autoimmune disease. Journal of Autoimmunity vol. 58, 1-11.
10.1016/j.jaut.2014.12.004
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6924
Farsky SHP, Santin JR, Takahama C, Machado ID, Teixeira S, Muscara MN, Pitta IR, Solito E et al. (2014). ANNEXIN A1 AND PPAR gamma ON RESOLUTION OF INFLAMMATION. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. vol. 115, 286-286.
Mauro C, De Rosa V, Marelli-Berg F, Solito E(2014). Metabolic syndrome and the immunological affair with the blood-brain barrier. Front Immunol vol. 5,
10.3389/fimmu.2014.00677
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6569
Queiroz CJDS, Nakata CMDAG, Solito E, Damazo AS(2014). Relationship between HPV and the biomarkers annexin A1 and p53 in oropharyngeal cancer. Infect Agent Cancer vol. 9,
10.1186/1750-9378-9-13
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6925
Girol AP, Mimura KKO, Drewes CC, Bolonheis SM, Solito E, Farsky SHP, Gil CD, Oliani SM(2013). Anti-inflammatory mechanisms of the annexin A1 protein and its mimetic peptide Ac2-26 in models of ocular inflammation in vivo and in vitro. J Immunol vol. 190, (11) 5689-5701.
10.4049/jimmunol.1202030
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6928
Cristante E, McArthur S, Mauro C, Maggioli E, Romero IA, Wylezinska-Arridge M, Couraud PO, Lopez-Tremoleda J et al.(2013). Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proc Natl Acad Sci U S A vol. 110, (3) 832-841.
10.1073/pnas.1209362110
Yazid S, Sinniah A, Solito E, Calder V, Flower RJ(2013). Anti-allergic cromones inhibit histamine and eicosanoid release from activated human and murine mast cells by releasing Annexin A1. PLoS One vol. 8, (3)
10.1371/journal.pone.0058963
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5240
Mehet DK, Philip J, Solito E, Buckingham JC, John CD(2012). Evidence from in vitro and in vivo studies showing that nuclear factor-κB within the pituitary folliculostellate cells and corticotrophs regulates adrenocorticotrophic hormone secretion in experimental endotoxaemia. J Neuroendocrinol vol. 24, (6) 862-873.
10.1111/j.1365-2826.2012.02285.x
Solito E, Sastre M(2012). Microglia function in Alzheimer's disease. Front Pharmacol vol. 3,
10.3389/fphar.2012.00014
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15584
McArthur S, Cristante E, Paterno M, Christian H, Roncaroli F, Gillies GE, Solito E(2010). Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. J Immunol vol. 185, (10) 6317-6328.
10.4049/jimmunol.1001095
Yazid S, Leoni G, Getting SJ, Cooper D, Solito E, Perretti M, Flower RJ(2010). Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol vol. 30, (9) 1718-1724.
10.1161/ATVBAHA.110.209536
Yazid S, Ayoub SS, Solito E, McArthur S, Vo P, Dufton N, Flower RJ(2010). Anti-allergic drugs and the Annexin-A1 system. Pharmacol Rep vol. 62, (3) 511-517.
10.1016/s1734-1140(10)70307-8
McArthur S, Yazid S, Christian H, Sirha R, Flower R, Buckingham J, Solito E(2009). Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization. FASEB J vol. 23, (11) 4000-4010.
10.1096/fj.09-131391
Yazid S, Solito E, Christian H, McArthur S, Goulding N, Flower R(2009). Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1. Biochem Pharmacol vol. 77, (12) 1814-1826.
10.1016/j.bcp.2009.03.010
McArthur S, Prasongchean W, Gillies G, Solito E(2008). A critical role for the anti-inflammatory protein annexin A1 in microglial phagocytosis. FUND CLIN PHARMACOL vol. 22, 23-23.
Yazid S, Solito E, Christian H, Goulding N, Flower R(2008). Further studies on the rapid glucocorticoid effects in the U937 monocytic cell line and its potentiation by cromoglycate-like drugs. FUND CLIN PHARMACOL vol. 22, 47-47.
Solito E, McArthur S, Christian H, Gavins F, Buckingham JC, Gillies GE(2008). Annexin A1 in the brain--undiscovered roles?. Trends Pharmacol Sci vol. 29, (3) 135-142.
10.1016/j.tips.2007.12.003
Damazo AS, Flower RJ, Solito E, Oliani SM(2008). Annexin-A1 gene expression during liver development and post-translation modification after experimental endotoxemia. INFLAMM RES vol. 57, (3) 97-103.
10.1007/s00011-007-7114-2
Hu NJ, Bradshaw J, Lauter H, Buckingham J, Solito E, Hofmann A(2008). Membrane-induced folding and structure of membrane-bound annexin A1 N-terminal peptides: Implications for annexin-induced membrane aggregation. BIOPHYS J vol. 94, (5) 1773-1781.
10.1529/biophysj.107.119685
John CD, Sahni V, Mehet D, Morris JF, Christian HC, Perretti M, Flower RJ, Solito E et al.(2007). Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides. FASEB J vol. 21, (4) 1037-1046.
10.1096/fj.06-7299com
Warne JP, John CD, Christian HC, Morris JF, Flower RJ, Sugden D, Solito E, Gillies GE et al.(2006). Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue. AM J PHYSIOL-ENDOC M vol. 291, (6) E1264-E1273.
10.1152/ajpendo.00655.2005
Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ, Solito E, Perretti M(2006). Antiflammin-2 activates the human formyl-peptide receptor like 1. ScientificWorldJournal vol. 6, 1375-1384.
10.1100/tsw.2006.247
https://qmro.qmul.ac.uk/xmlui/handle/123456789/52203
Buckingham J, John C, Solito E, Flower R, Christian H, Morris J(2006). Annexin 1: a mediator of glucocorticoid action at the neuroendocrine-immune interface. ACTA PHARMACOL SIN vol. 27, 1-1.
Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G, Solito E, Parente L(2006). Down-regulation of annexin-1 expression in thyroid cancers is associated with tumour aggressiveness. ACTA PHARMACOL SIN vol. 27, 65-65.
Solito E, Christian HC, Festa M, Mulla A, Tierney T, Flower RJ, Buckingham JC(2006). Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface. FASEB J vol. 20, (9) 1498-+.
10.1096/fj.05-5139fje
Solito E, Christian HC, Festa M, Mulla A, Tierney T, Flower RJ, Buckingham JC(2006). Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface. FASEB J vol. 20, (9) 1498-1500.
10.1096/fj.05-5319fje
Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G, Solito E, Parente L(2006). Annexin-1 downregulation in thyroid cancer correlates to the degree of tumor differentiation. Cancer Biol Ther vol. 5, (6) 643-647.
10.4161/cbt.5.6.2700
Buckingham JC, Sahni V, Morris JF, Christian HC, Solito E, John CD (2006). Annexin 1 dependent actions of glucocorticoids in the anterior pituitary gland - role of the formyl peptide receptor family. FRONTIERS IN NEUROENDOCRINOLOGY. vol. 27, 53-54.
10.1016/j.yfrne.2006.03.109
Buckingham JC, Mulla A, Tierney T, Morris J, Christian HC, Solito E (2006). The cellular exportation of annexin 1 requires post-translational modification. FRONTIERS IN NEUROENDOCRINOLOGY. vol. 27, 85-85.
10.1016/j.yfrne.2006.03.186
Rodrigues-Lisoni FC, Mehet DK, Peitl P, John CD, da Silva WA, Tajara E, Buckingham JC, Solito E(2006). In vitro and in vivo studies on CCR10 regulation by Annexin A1 (vol 580, pg 1431, 2006). FEBS LETT vol. 580, (7) 1908-1908.
10.1016/j.febslet.2006.02.026
Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D, Perretti M(2006). Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. BLOOD vol. 107, (5) 2123-2130.
10.1182/blood-2005-08-3099
Rodrigues-Lisoni FC, Mehet DK, Peitl P, John CD, da Silva Júnior WA, Tajara E, Buckingham JC, Solito E(2006). In vitro and in vivo studies on CCR10 regulation by Annexin A1. FEBS Lett vol. 580, (5) 1431-1438.
10.1016/j.febslet.2006.01.072
Buckingham JC, John CD, Solito E, Tierney T, Flower RJ, Christian H, Morris J (2006). Annexin 1, glucocorticoids, and the neuroendocrine-immune interface. NEUROENDOCRINE AND IMMUNE CROSSTALK. Editors: Chrousos, GP, Kaltsas, GA, Mastorakos, G, vol. 1088, 396-409.
10.1196/annals.1366.002
Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G, Solito E, Parente L(2005). Induction of annexin-1 during TRAIL-induced apoptosis in thyroid carcinoma cells. Cell Death Differ vol. 12, (10) 1358-1360.
10.1038/sj.cdd.4401645
Mulla A, Leroux C, Solito E, Buckingham JC(2005). Correlation between the antiinflammatory protein annexin 1 (lipocortin 1) and serum cortisol in subjects with normal and dysregulated adrenal function. J Clin Endocrinol Metab vol. 90, (1) 557-562.
10.1210/jc.2004-1230
Perretti M, Solito E(2004). Annexin 1 and neutrophil apoptosis. BIOCHEMICAL SOCIETY TRANSACTIONS vol. 32, 507-510.
10.1042/BST0320507
John CD, Christian HC, Morris JF, Flower RJ, Solito E, Buckingham JC(2004). Annexin 1 and the regulation of endocrine function. TRENDS ENDOCRIN MET vol. 15, (3) 103-109.
10.1016/j.tem.2004.02.001
Parente L, Solito E(2004). Annexin 1: more than an anti-phospholipase protein. Inflamm Res vol. 53, (4) 125-132.
10.1007/s00011-003-1235-z
Mulla A, Christian HC, Solito E, Mendoza N, Morris JF, Buckingham JC(2004). Expression, subcellular localization and phosphorylation status of annexins 1 and 5 in human pituitary adenomas and a growth hormone-secreting carcinoma. Clin Endocrinol (Oxf) vol. 60, (1) 107-119.
10.1111/j.1365-2265.2004.01936.x
Tierney T, Christian HC, Morris JF, Solito E, Buckingham JC(2003). Evidence from studies on co-cultures of TtT/GF and AtT20 cells that Annexin 1 acts as a paracrine or juxtacrine mediator of the early inhibitory effects of glucocorticoids on ACTH release. J Neuroendocrinol vol. 15, (12) 1134-1143.
10.1111/j.1365-2826.2003.01111.x
John CD, Christian HC, Morris JF, Flower RJ, Solito E, Buckingham JC(2003). Kinase-dependent regulation of the secretion of thyrotrophin and luteinizing hormone by glucocorticoids and annexin 1 peptides. J Neuroendocrinol vol. 15, (10) 946-957.
10.1046/j.1365-2826.2003.01081.x
Buckingham JC, Solito E, John C, Tierney T, Taylor A, Flower R, Christian H, Morris J(2003). Annexin 1: a paracrine/juxtacrine mediator of glucorticoid action in the neuroendocrine system. Cell Biochem Funct vol. 21, (3) 217-221.
10.1002/cbf.1076
Buckingham JC, Solito E, John C, Tierney T, Taylor A, Flower R, Christian H, Morris J (2003). Annexin 1: a paracrine/juxtacrine mediator of glucorticoid in the action in the neuroendocrine system. CELL BIOCHEMISTRY AND FUNCTION. vol. 21, 217-221.
10.1027/cbf.1076
de Coupade C, Solito E, Levine JD(2003). Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937. Br J Pharmacol vol. 140, (1) 133-145.
10.1038/sj.bjp.0705413
Solito E, Kamal A, Russo-Marie F, Buckingham JC, Marullo S, Perretti M(2003). A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils. FASEB J vol. 17, (9) 1544-+.
10.1096/fj.02-0941fje
Croxtall JD, Gilroy DW, Solito E, Choudhury Q, Ward BJ, Buckingham JC, Flower RJ(2003). Attenuation of glucocorticoid functions in an Anx-A1-/- cell line. Biochem J vol. 371, (Pt 3) 927-935.
10.1042/BJ20021856
Solito E, Mulla A, Morris JF, Christian HC, Flower RJ, Buckingham JC(2003). Dexamethasone induces rapid serine-phosphorylation and membrane translocation of annexin 1 in a human folliculostellate cell line via a novel nongenomic mechanism involving the glucocorticoid receptor, protein kinase c, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase. ENDOCRINOLOGY vol. 144, (4) 1164-1174.
10.1210/en.2002-220592
Solito E, Perretti M (2003). Exogenous annexin 1 promotes human neutrophil apoptosis. BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U7-U7.
PERRETTI M, Marullo S, Buckingham JC, Russo-Marie F, Solito E, Kamal A (2003). A novel calcium-dependent pro-apoptotic effect of annexin 1 on human neutrophils. FASEB J. vol. 17, 1544-1546.
10.1096/fj.02-0941fje
FLOWER RJ, John C, Solito E, Morris J, Tierney T, Taylor A, Christian H, Buckingham JC(2003). Annexin 1: a paracrine/juxtacrine mediator of glucorticoid action in the neuroendocrine system. Cell Biochemistry and Function. vol. 21, (3) 217-221.
10.1002/cbf.1076
FLOWER RJ, Morris JF, Christian HC, Buckingham JC, Solito E, John CD(2003). Kinase-Dependent Regulation of the Secretion of Thyrotrophin and Luteinizing Hormone By Glucocorticoids and Annexin 1 Peptides. J Neuroendocrinol. vol. 15, (10) 946-957.
10.1046/j.1365-2826.2003.01081.x
Perretti M, Chiang N, La M, Fierro IM, Marullo S, Getting SJ, Solito E, Serhan CN(2002). Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor. Nat Med vol. 8, (11) 1296-1302.
10.1038/nm786
Perretti M, Ingegnoli F, Wheller SK, Blades MC, Solito E, Pitzalis C(2002). Annexin 1 modulates monocyte-endothelial cell interaction in vitro and cell migration in vivo in the human SCID mouse transplantation model. J Immunol vol. 169, (4) 2085-2092.
10.4049/jimmunol.169.4.2085
Perretti M, La M, Solito E (2002). Annexin 1 interacts with L-selectin following neutrophil adhesion to endothelial cells. FASEB J. vol. 16, A1049-A1049.
Perretti M, Blades MC, Wheller SK, Wahid S, Solito E, Pitzalis C (2002). Monocytic cells over-expressing annexin 1 have reduced transmigration in vitro and elicitation in vivo. FASEB J. vol. 16, A598-A598.
Solito E, Mulla A, Buckingham JC(2002). Dexamethasone induces serine phosphorylation of annexin 1: Involvement of PKC and PI3-kinase. BRIT J PHARMACOL vol. 135,
Mulla A, Buckingham JC, Solito E(2002). LPS acts via IL-6 and IL-1 to modulate the expression and phosphorylation of annexin 1 in cell lines derived from the putative microglia of the neuroendocrine system. BRIT J PHARMACOL vol. 135,
FLOWER RJ, Buckingham J, Christian H, Solito E, John C, Cover P, Morris J(2002). Annexin 1-dependent actions of glucocorticoids in the anterior pituitary gland: roles of the N-terminal domain and protein kinase C. Endocrinology. vol. 143, (8) 3060-3070.
10.1210/endo.143.8.8965
de Coupade C, Ajuebor MN, Russo-Marie F, Perretti M, Solito E(2001). Cytokine modulation of liver annexin 1 expression during experimental endotoxemia. AM J PATHOL vol. 159, (4) 1435-1443.
10.1016/S0002-9440(10)62530-8
Kamal AM, Smith SF, De Silva Wijayasinghe M, Solito E, Corrigan CJ(2001). An annexin 1 (ANXA1)-derived peptide inhibits prototype antigen-driven human T cell Th1 and Th2 responses in vitro. Clin Exp Allergy vol. 31, (7) 1116-1125.
10.1046/j.1365-2222.2001.01137.x
Perretti M, Getting SJ, Solito E, Murphy PM, Gao JL(2001). Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics. AM J PATHOL vol. 158, (6) 1969-1973.
10.1016/S0002-9440(10)64667-6
John CD, Solito E, Mulla A, Morris JF, Flower RJ, Buckingham JC(2001). Dexamethasone induces serine phosphorylation of annexin 1 in pituitary cells and suppresses ACTH release by a PKC-dependent mechanism. BRIT J PHARMACOL vol. 133, U20-U20.
Solito E, de Coupade C, Canaider S, Goulding NJ, Perretti M(2001). Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation. BRIT J PHARMACOL vol. 133, (2) 217-228.
10.1038/sj.bjp.0704054
Solito E, Tissot M, Russo-Marie F, Marullo S(2000). Extracellular annexin-1 accelerates apoptosis of human polymorphonuclears neutrophils. MOL BIOL CELL vol. 11, 462A-463A.
D'Amico M, Di Filippo C, La M, Solito E, McLean PG, Flower RJ, Oliani SM, Perretti M(2000). Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment. FASEB J vol. 14, (13) 1867-1869.
10.1096/fj.99-0602fje
Solito E, Romero IA, Marullo S, Russo-Marie F, Weksler BB(2000). Annexin 1 binds to U937 monocytic cells and inhibits their adhesion to microvascular endothelium: involvement of the alpha 4 beta 1 integrin. J Immunol vol. 165, (3) 1573-1581.
10.4049/jimmunol.165.3.1573
Mulla A, Christian H, Morris J, Mendoza N, Solito E, Buckingham J(2000). Expression of annexins 1 and 5 in human pituitary tumours. J PHYSIOL-LONDON vol. 525, 53P-54P.
Solito E, Tissot M, Russo-Marie F, Marullo S(2000). Extracellular Annexin 1 induces apoptosis of human polymorphonuclear neutrophils. FASEB J vol. 14, (8) A1357-A1357.
Le Maire V, Solito E, Russo-Marie F, Hernvann A, Le Marechal H, Ekindjian OG, Aussel C(2000). System A neutral amino acid transporter regulation by interleukin-1beta in human osteoarthritic synovial cells: evidence for involvement of prostaglandin E(2) as a second messenger. J Cell Physiol vol. 183, (1) 65-73.
10.1002/(SICI)1097-4652(200004)183:1<65::AID-JCP8>3.0.CO;2-H
Canaider S, Solito E, de Coupade C, Flower RJ, Russo-Marie F, Goulding NJ, Perretti M(2000). Increased apoptosis in U937 cells over-expressing lipocortin 1 (annexin I). Life Sci vol. 66, (18) PL265-PL270.
10.1016/s0024-3205(00)00500-2
Perretti M, Solito E, La M, Russo-Marie F, Marullo S, D'Amico M, Flower RJ(2000). Annexin 1 activates human neutrophils: A mechanism for its anti-inflammatory in vivo effect. FASEB J vol. 14, (4) A8-A8.
de Coupade C, Gillet R, Bennoun M, Briand P, Russo-Marie F, Solito E(2000). Annexin 1 expression and phosphorylation are upregulated during liver regeneration and transformation in antithrombin III SV40 T large antigen transgenic mice. Hepatology vol. 31, (2) 371-380.
10.1002/hep.510310217
D'Amico M, Di Filippo C, Solito E, Flower RJ, Perretti M(2000). Lipocortin 1 inhibits myocardial infarct by reducing local neutrophil infiltration. BRIT J PHARMACOL vol. 129, U56-U56.
Gidon-Jeangirard C, Solito E, Hofmann A, Russo-Marie F, Freyssinet JM, Martínez MC(1999). Annexin V counteracts apoptosis while inducing Ca(2+) influx in human lymphocytic T cells. Biochem Biophys Res Commun vol. 265, (3) 709-715.
10.1006/bbrc.1999.1752
Young KA, Hirst WD, Solito E, Wilkin GP(1999). De novo expression of lipocortin-1 in reactive microglia and astrocytes in kainic acid lesioned rat cerebellum. Glia vol. 26, (4) 333-343.
10.1002/(sici)1098-1136(199906)26:4<333::aid-glia7>3.0.co;2-s
John CD, Cover PO, Taylor AD, Morris JF, Flower RJ, Solito E, Buckingham JC(1999). Evidence from in vivo and in vitro studies that the inhibitory actions of lipocortin 1 on anterior pituitary function require amino acid residues 13-26. BRIT J PHARMACOL vol. 126, U74-U74.
Canaider S, Solito E, Goulding NJ, Flower RJ, Perretti M(1999). Increased apoptosis in cells overexpressing lipocortin 1. BRIT J PHARMACOL vol. 126, U26-U26.
Raguenes-Nicol C, Russo-Marie F, Domage G, Diab N, Solito E, Dray F, Mace JL, Streichenberger G(1999). Anti-inflammatory mechanism of alminoprofen: action on the phospholipid metabolism pathway. Biochem Pharmacol vol. 57, (4) 433-443.
10.1016/s0006-2952(98)00312-8
Raugei G, Degl'Innocenti D, Chiarugi P, Solito E, Modesti A, Ramponi G(1999). Preferential accumulation of muscle type acylphosphatase in the nucleus during differentiation. Biochem Mol Biol Int vol. 47, (1) 127-136.
10.1080/15216549900201123
Lim LH, Solito E, Russo-Marie F, Flower RJ, Perretti M(1998). Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1. Proc Natl Acad Sci U S A vol. 95, (24) 14535-14539.
10.1073/pnas.95.24.14535
Solito E, Raguenes-Nicol C, de Coupade C, Bisagni-Faure A, Russo-Marie F(1998). U937 cells deprived of endogenous annexin 1 demonstrate an increased PLA2 activity. Br J Pharmacol vol. 124, (8) 1675-1683.
10.1038/sj.bjp.0701991
Solito E, de Coupade C, Parente L, Flower RJ, Russo-Marie F(1998). IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein. Cytokine vol. 10, (7) 514-521.
10.1006/cyto.1997.0325
Solito E, de Coupade C, Parente L, Flower RJ, Russo-Marie F(1998). Human annexin 1 is highly expressed during the differentiation of the epithelial cell line A 549: involvement of nuclear factor interleukin 6 in phorbol ester induction of annexin 1. Cell Growth Differ vol. 9, (4) 327-336.
Dubois T, Mira JP, Feliers D, Solito E, Russo-Marie F, Oudinet JP(1998). Annexin V inhibits protein kinase C activity via a mechanism of phospholipid sequestration. Biochem J vol. 330 ( Pt 3), 1277-1282.
10.1042/bj3301277
Lim LHK, Getting SJ, Das AM, Solito E, Flower RJ, Perretti M(1997). Inhibition of neutrophil : endothelium interaction in murine post-capillary venules by lipocortin 1. BRIT J PHARMACOL vol. 122, U54-U54.
Voermans PH, Go KG, ter Horst GJ, Ruiters MH, Solito E, Parente L(1997). Expression of annexin and annexin-mRNA in rat brain under influence of steroid drugs. Acta Neurochir Suppl vol. 70, 222-224.
10.1007/978-3-7091-6837-0_68
Cifone MG, Cironi L, Roncaioli P, Martinotti S, Toniato E, Cilenti L, Botti D, Solito E et al.(1996). Phospholipase A(2) activity and calpactin I levels in rat lymphokine-activated killer cells: Correlation with the cytotoxic activity. CELL IMMUNOL vol. 170, (2) 274-282.
10.1006/cimm.1996.0161
Ambrosetti DC, Palla E, Mirtella A, Galeotti C, Solito E, Navarra P, Parente L, Melli M(1996). Synthetic alleles at position 121 define a functional domain of human interleukin-1 beta. Eur J Biochem vol. 238, (2) 308-316.
10.1111/j.1432-1033.1996.0308z.x
Voermans PH, Go KG, Horst GJ, Ruiters MH, Solito E, Parente L(1996). Induction of annexin-1 at transcriptional and post-transcriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F. Mediators Inflamm vol. 5, (5) 370-378.
10.1155/S0962935196000531
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15596
Parente L, Solito E(1994). Association between glucocorticosteroids and lipocortin 1. Trends Pharmacol Sci vol. 15, (10)
10.1016/0165-6147(94)90154-6
Solito E, Nuti S, Parente L(1994). Dexamethasone-induced translocation of lipocortin (annexin) 1 to the cell membrane of U-937 cells. Br J Pharmacol vol. 112, (2) 347-348.
10.1111/j.1476-5381.1994.tb13075.x
PARENTE L, NUTI S, SOLITO E(1994). DEXAMETHASONE INDUCES THE TRANSLOCATION OF LIPOCORTIN-1 TO THE MEMBRANE OF HUMAN MONOCYTIC U-937 CELLS. BRIT J PHARMACOL vol. 111, P72-P72.
GO KG, ZUIDERVEEN F, DELEY L, TERHAAR JG, PARENTE L, SOLITO E, MOLENAAR WM(1994). EFFECT OF STEROIDS ON BRAIN LIPOCORTIN IMMUNOREACTIVITY. ACTA NEUROCHIR101-103.
Go KG, Zuiderveen F, De Ley L, Ter Haar JG, Parente L, Solito E, Molenaar WM(1994). Effect of steroids on brain lipocortin immunoreactivity. Acta Neurochir Suppl (Wien) vol. 60, 101-103.
10.1007/978-3-7091-9334-1_26
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6966
SOLITO E, PALLA E, BENSI G, FASSINA G, MELLI M, PARENTE L(1994). IDENTIFICATION OF ACTIVE-SITES OF INTERLEUKIN-1-BETA BY LOOP SUBSTITUTION AND SITE-DIRECTED MUTAGENESIS. BRIT J PHARMACOL vol. 111, P31-P31.
Go KG, Ter Haar JG, de Ley L, Zuiderveen F, Parente L, Solito E, Molenaar WM(1994). The effect of steroid treatment on lipocortin immunoreactivity of rat brain. Mediators Inflamm vol. 3, (3) 177-180.
10.1155/S0962935194000232
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11972
De Caterina R, Sicari R, Giannessi D, Paggiaro PL, Paoletti P, Lazzerini G, Bernini W, Solito E et al.(1993). Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids. J Appl Physiol (1985) vol. 75, (6) 2368-2375.
10.1152/jappl.1993.75.6.2368
Palla E, Bensi G, Solito E, Buonamassa DT, Fassina G, Raugei G, Spano F, Galeotti C et al.(1993). Loop substitution as a tool to identify active sites of interleukin-1 beta. J Biol Chem vol. 268, (18) 13486-13492.
BECHERUCCI C, PERRETTI M, SOLITO E, GALEOTTI CL, PARENTE L(1993). CONCEIVABLE DIFFERENCE IN THE ANTIINFLAMMATORY MECHANISMS OF LIPOCORTIN-1 AND LIPOCORTIN-5. MEDIAT INFLAMM vol. 2, (2) 109-113.
10.1155/S0962935193000158
RUBARTELLI A, BAJETTO A, BONIFACI N, DIBLAS E, SOLITO E, SITIA R (1993). A NOVEL WAY TO GET OUT OF THE CELL. CYTOTECHNOLOGY. vol. 11, 37-40.
10.1007/BF00746049
Rubartelli A, Bajetto A, Bonifaci N, Di Blas E, Solito E, Sitia R(1993). A novel way to get out of the cell. Cytotechnology vol. 11 Suppl 1, S37-S40.
10.1007/bf00746049
Becherucci C, Perretti M, Solito E, Galeotti CL, Parente L(1993). Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5. Mediators Inflamm vol. 2, (2) 109-113.
10.1155/S0962935193000158
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15602
Solito E, De Caterina R, Giannessi D, Paggiaro PL, Sicari R, Parente L(1993). Studies on the induction of lipocortin-1 by glucocorticoids. Ann Ist Super Sanita vol. 29, (3) 391-394.
Parente L, Solito E, Giannessi P, Paggiari P, Sicari R, De Caterina R(1992). Inhibition of eicosanoid formation and lipocortin induction by glucocorticoids in human cell lines and in patients with inflammatory lung disease. Pharmacol Res vol. 26 Suppl 2, 44-45.
10.1016/1043-6618(92)90591-x
Solito E, Raugei G, Melli M, Parente L(1992). Glucocorticoid effect on lipocortin mRNA expression in U-937 cells. Pharmacol Res vol. 25 Suppl 1, 13-14.
10.1016/1043-6618(92)90517-f
Perretti M, Solito E, Parente L(1992). Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice. Agents Actions vol. 35, (1-2) 71-78.
10.1007/BF01990954
SOLITO E, RAUGEI G, MELLI M, PARENTE L(1991). DEXAMETHASONE INDUCES THE EXPRESSION OF THE MESSENGER-RNA OF LIPOCORTIN-1 AND LIPOCORTIN-2 AND THE RELEASE OF LIPOCORTIN-1 AND LIPOCORTIN-5 IN DIFFERENTIATED, BUT NOT UNDIFFERENTIATED U-937 CELLS. FEBS LETT vol. 291, (2) 238-244.
10.1016/0014-5793(91)81293-H
Solito E, Raugei G, Melli M, Parente L(1991). Dexamethasone induces the expression of the mRNA of lipocortin 1 and 2 and the release of lipocortin 1 and 5 in differentiated, but not undifferentiated U-937 cells. FEBS Lett vol. 291, (2) 238-244.
10.1016/0014-5793(91)81293-h
Perretti M, Becherucci C, Mugridge KG, Solito E, Silvestri S, Parente L(1991). A novel anti-inflammatory peptide from human lipocortin 5. Br J Pharmacol vol. 103, (2) 1327-1332.
10.1111/j.1476-5381.1991.tb09788.x
SOLITO E, RAUGEI G, MELLI M, PARENTE L(1991). EFFECT OF DEXAMETHASONE AND PHORBOL-MYRISTATE ACETATE ON LIPOCORTIN-1, LIPOCORTIN-2 AND LIPOCORTIN-5 MESSENGER-RNA AND PROTEIN-SYNTHESIS. ADV PROSTAG THROMB L vol. 21, 291-294.
Solito E, Raugei G, Melli M, Parente L(1991). Effect of dexamethasone and phorbol myristate acetate on lipocortin 1, 2 and 5 mRNA and protein synthesis. Adv Prostaglandin Thromboxane Leukot Res vol. 21A, 291-294.
Boraschi D, Villa L, Ghiara P, Tagliabue A, Mengozzi M, Solito E, Parente L, Silvestri S et al.(1991). Mechanism of acute toxicity of IL-1 beta in mice. Eur Cytokine Netw vol. 2, (1) 61-67.
Becherucci C, Solito E, Perretti M, Mugridge KG, Galeotti CL, Parente L(1990). Purification and biological activity of human lipocortin 2. Pharmacol Res vol. 22 Suppl 1, 29-30.
10.1016/1043-6618(90)90792-c
Parente L, Becherucci C, Perretti M, Solito E, Mugridge KG, Galeotti CL, Raugei G, Melli M et al.(1990). Are the lipocortins the second messengers of the anti-inflammatory action of glucocorticoids?. Prog Clin Biol Res vol. 349, 55-68.
Parente L, Mugridge KG, Perretti M, Solito E(1990). In vitro and in vivo activation of phospholipase A<inf>2</inf> by interleukin-1. Pharmacological Research vol. 22,
10.1016/1043-6618(90)90413-8
Solito E, Parente L(1989). Modulation of phospholipase A2 activity in human fibroblasts. Br J Pharmacol vol. 96, (3) 656-660.
10.1111/j.1476-5381.1989.tb11865.x
SOLITO E, PARENTE L(1988). ACTIVATION OF PHOSPHOLIPASE-A2 BY INTERLEUKIN-1 IN HUMAN-FIBROBLASTS. LYMPHOKINE RES vol. 7, (3) 261-261.
Solito E, Busoni P, Bini L(1985). [Relational perspective in a district service for the substance-dependent]. Minerva Psichiatr vol. 26, (3) 267-269.
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