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Publications:  Mr Rayomand Khambata

Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM, Ahluwalia A(2020). The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway. Pharmacological reviews vol. 72, (3) 692-766.
10.1124/pr.120.019240
Massimo G, Ahluwalia A, Khambata R, Borghi C (2019). Natural Mutations of the Human Xdh Impact upon the Nitric Oxide-generating Capacity of Xanthine Oxidoreductase. FREE RADICAL BIOLOGY AND MEDICINE. vol. 145, S116-S116.
10.1016/j.freeradbiomed.2019.10.310
Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, S. Watson D, Barnes MR et al.(2018). Sex differences in the nitrate-nitrite-NO <sup>•</sup> pathway: Role of oral nitrate-reducing bacteria. Free Radical Biology and Medicine vol. 126, 113-121.
10.1016/j.freeradbiomed.2018.07.010
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55110
Yellon DM, He Z, Khambata R, Ahluwalia A, Davidson SM(2018). The GTN patch: a simple and effective new approach to cardioprotection?. Basic Research in Cardiology vol. 113, (3)
10.1007/s00395-018-0681-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/41443
Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A, Jones DA(2017). Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials. JRSM Cardiovasc Dis vol. 6, 2048004017725988-2048004017725988.
10.1177/2048004017725988
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34994
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. (2017). Sex differences in the inflammatory response and inflammation-induced vascular dysfunction. LANCET. Conference: FASEB vol. 389, 20-20.
10.1016/s0140-6736(17)30416-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22462
AHLUWALIA A(2017). The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque. Proceedings of the National Academy of Sciences of USA
10.1073/pnas.1613063114
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18789
AHLUWALIA A(2016). Accelerated resolution underlies sex differences in the inflammatory response in human. Journal of Clinical Investigation vol. 127, (1) 169-182.
10.1172/JCI89429.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18792
Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A, Ahluwalia A(2016). Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention. Heart
10.1136/heartjnl-2016-309748
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17062
Khambata RS, Ghosh SM, Rathod KS, Thevathasan T, Ahluwalia A (2016). Dietary Nitrate Supresses Leukocyte Recruitment and Activation in Apolipoprotein E Knockout Mice. FASEB JOURNAL. vol. 30,
Filomena F, Khambata R, Ahluwalia A (2016). Dietary nitrate suppresses platelet reactivity in Apolipoprotein E Knockout Mice. FASEB JOURNAL. vol. 30,
Rathod KS, Siddiqui U, Hartley A, Khambata RS, Ahluwalia A (2016). Investigation of the influence of sex on cantharidin-induced inflammation in healthy volunteers. FASEB JOURNAL. vol. 30,
Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V et al.(2016). Dietary nitrate improves vascular function in patients with hypercholesterolemia: A randomized, double-blind, placebo-controlled study. American Journal of Clinical Nutrition vol. 103, (1) 25-38.
10.3945/ajcn.115.116244
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14986
Fernandes D, Khambata R, Ahluwalia A (2015). Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis. CIRCULATION. vol. 132,
Khambata RS, Ghosh SM, Ahluwalia A(2015). "Repurposing" of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension. Antioxidants and Redox Signaling vol. 23, (4) 340-353.
10.1089/ars.2015.6254
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6956
Velmurugan S, Ghosh SM, Khambata RS, Van Eijl S, Robertson A, Chowdhury TA, Ahluwalia A (2015). Acute administration of dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia. EUROPEAN HEART JOURNAL. vol. 36, 257-257.
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2015). Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532)). Free Radical Biology and Medicine vol. 84,
10.1016/j.freeradbiomed.2015.03.015
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10411
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A(2015). Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study. Hypertension vol. 65, (2) 320-327.
10.1161/HYPERTENSIONAHA.114.04675
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6639
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2015). Erratum to "Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex" [Free Radic. Biol. Med. 65 (2013) 1521-1532]. Free Radical Biology and Medicine
10.1016/j.freeradbiomed.2015.03.015
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7745
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A(2014). Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients: A Randomized, Phase 2, Double-Blind, Placebo-Controlled Study. Hypertension
10.1161/HYPERTENSIONAHA.114.04675
Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T, Ahluwalia A(2014). Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia. Nitric Oxide vol. 42C,
10.1016/j.niox.2014.09.141
Rathod K, Ghosh S, Khambata R, Ahluwalia A(2014). Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity. Nitric Oxide vol. 42C,
10.1016/j.niox.2014.09.119
Velmurugan S, Ghosh SM, Khambata RS, Robertson AC, Van Eijl TJA, Chowdhury TA, Ahluwalia A (2014). Dietary nitrate improves endothelial function, vascular stiffness and modifies platelet markers of atherogenesis in hypercholesterolemia. EUROPEAN HEART JOURNAL. vol. 35, 1047-1047.
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ et al.(2014). Endothelial C-type natriuretic peptide maintains vascular homeostasis. J Clin Invest vol. 124, (9) 4039-4051.
10.1172/JCI74281
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6288
Ghosh S, Khambata R, Ahluwalia A (2014). DIETARY INORGANIC NITRATE REDUCES INFLAMMATORY CELL RECRUITMENT IN MICE. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. vol. 115, 17-17.
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2013). Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex. Free Radic Biol Med vol. 65, 1521-1532.
10.1016/j.freeradbiomed.2013.06.031
Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S et al.(2013). Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential. Hypertension vol. 61, (5) 1091-1102.
10.1161/HYPERTENSIONAHA.111.00933
Jones DA, Khambata RS, Mathur A, Ahluwalia A (2013). Sodium nitrite promotes the viability and proliferation of endothelial cells but inhibits the growth of smooth muscle cells under hypoxia. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 31, S22-S22.
10.1016/j.niox.2013.02.024
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2013). Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex. Free Radical Biology and Medicine vol. 65, 1521-1532.
10.1016/j.freeradbiomed.2013.06.031
Moyes AJ, Khambata RS, Ahluwalia A, Hobbs AJ(2012). Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide. CIRCULATION vol. 126, (21)
Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V, Ahluwalia A(2012). Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP. CIRCULATION vol. 126, (21)
Bubb KJ, Khambata RS, Ahluwalia A(2012). Sexual dimorphism in rodent models of hypertension and atherosclerosis. Br J Pharmacol vol. 167, (2) 298-312.
10.1111/j.1476-5381.2012.02036.x
Khambata R, Ghosh S, Ahluwalia A (2012). Nitrite superfusion reduces leukocyte-endothelial interactions in the mouse cremaster model. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 27, S15-S15.
10.1016/j.niox.2012.04.055
Khambata RS, Panayiotou CM, Hobbs AJ(2011). Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide. Br J Pharmacol vol. 164, (2b) 584-597.
10.1111/j.1476-5381.2011.01400.x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14813
Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ et al.(2011). Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol vol. 31, (5) 1075-1083.
10.1161/ATVBAHA.111.223545
Lumsden NG, Khambata RS, Hobbs AJ(2010). C-type Natriuretic Peptide (CNP): Cardiovascular Roles and Potential as a Therapeutic Target. CURRENT PHARMACEUTICAL DESIGN vol. 16, (37) 4080-4088.
Khambata RS, Panayiotou CM, Xiao F, Hobbs AJ(2010). The anti-atherogenic potential of C-type natriuretic peptide: Disparate regulation of endothelial and vascular smooth muscle cell proliferation via natriuretic peptide receptor-C. FASEB JOURNAL vol. 24,
Lumsden NG, Khambata RS, Hobbs AJ(2010). C-type natriuretic peptide (CNP): cardiovascular roles and potential as a therapeutic target. Curr Pharm Des vol. 16, (37) 4080-4088.
10.2174/138161210794519237
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