Publications:  Mr Rayomand Khambata

Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM, Ahluwalia A(2020). The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway. Pharmacological reviews vol. 72, (3) 692-766.

Massimo G, Ahluwalia A, Khambata R, Borghi C (2019). Natural Mutations of the Human Xdh Impact upon the Nitric Oxide-generating Capacity of Xanthine Oxidoreductase. FREE RADICAL BIOLOGY AND MEDICINE. vol. 145, S116-S116.

Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, S. Watson D, Barnes MR et al.(2018). Sex differences in the nitrate-nitrite-NO ^• pathway: Role of oral nitrate-reducing bacteria. Free Radical Biology and Medicine vol. 126, 113-121.

Yellon DM, He Z, Khambata R, Ahluwalia A, Davidson SM(2018). The GTN patch: a simple and effective new approach to cardioprotection?. Basic Research in Cardiology vol. 113, (3)

Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A, Jones DA(2017). Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials. JRSM Cardiovasc Dis vol. 6, 2048004017725988-2048004017725988.

Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. (2017). Sex differences in the inflammatory response and inflammation-induced vascular dysfunction. LANCET. Conference: FASEB vol. 389, 20-20.

AHLUWALIA A(2017). The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque. Proceedings of the National Academy of Sciences of USA

AHLUWALIA A(2016). Accelerated resolution underlies sex differences in the inflammatory response in human. Journal of Clinical Investigation vol. 127, (1) 169-182.

Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A, Ahluwalia A(2016). Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention. Heart

Khambata RS, Ghosh SM, Rathod KS, Thevathasan T, Ahluwalia A (2016). Dietary Nitrate Supresses Leukocyte Recruitment and Activation in Apolipoprotein E Knockout Mice. FASEB JOURNAL. vol. 30,

Filomena F, Khambata R, Ahluwalia A (2016). Dietary nitrate suppresses platelet reactivity in Apolipoprotein E Knockout Mice. FASEB JOURNAL. vol. 30,

Rathod KS, Siddiqui U, Hartley A, Khambata RS, Ahluwalia A (2016). Investigation of the influence of sex on cantharidin-induced inflammation in healthy volunteers. FASEB JOURNAL. vol. 30,

Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V et al.(2016). Dietary nitrate improves vascular function in patients with hypercholesterolemia: A randomized, double-blind, placebo-controlled study. American Journal of Clinical Nutrition vol. 103, (1) 25-38.

Fernandes D, Khambata R, Ahluwalia A (2015). Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis. CIRCULATION. vol. 132,

Khambata RS, Ghosh SM, Ahluwalia A(2015). "Repurposing" of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension. Antioxidants and Redox Signaling vol. 23, (4) 340-353.

Velmurugan S, Ghosh SM, Khambata RS, Van Eijl S, Robertson A, Chowdhury TA, Ahluwalia A (2015). Acute administration of dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia. EUROPEAN HEART JOURNAL. vol. 36, 257-257.

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2015). Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532)). Free Radical Biology and Medicine vol. 84,

Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A(2015). Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study. Hypertension vol. 65, (2) 320-327.

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2015). Erratum to "Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex" [Free Radic. Biol. Med. 65 (2013) 1521-1532]. Free Radical Biology and Medicine

Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A(2014). Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients: A Randomized, Phase 2, Double-Blind, Placebo-Controlled Study. Hypertension

Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T, Ahluwalia A(2014). Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia. Nitric Oxide vol. 42C,

Rathod K, Ghosh S, Khambata R, Ahluwalia A(2014). Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity. Nitric Oxide vol. 42C,

Velmurugan S, Ghosh SM, Khambata RS, Robertson AC, Van Eijl TJA, Chowdhury TA, Ahluwalia A (2014). Dietary nitrate improves endothelial function, vascular stiffness and modifies platelet markers of atherogenesis in hypercholesterolemia. EUROPEAN HEART JOURNAL. vol. 35, 1047-1047.

Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ et al.(2014). Endothelial C-type natriuretic peptide maintains vascular homeostasis. J Clin Invest vol. 124, (9) 4039-4051.

Ghosh S, Khambata R, Ahluwalia A (2014). DIETARY INORGANIC NITRATE REDUCES INFLAMMATORY CELL RECRUITMENT IN MICE. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. vol. 115, 17-17.

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2013). Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex. Free Radic Biol Med vol. 65, 1521-1532.

Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S et al.(2013). Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential. Hypertension vol. 61, (5) 1091-1102.

Jones DA, Khambata RS, Mathur A, Ahluwalia A (2013). Sodium nitrite promotes the viability and proliferation of endothelial cells but inhibits the growth of smooth muscle cells under hypoxia. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 31, S22-S22.

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.(2013). Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex. Free Radical Biology and Medicine vol. 65, 1521-1532.

Moyes AJ, Khambata RS, Ahluwalia A, Hobbs AJ(2012). Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide. CIRCULATION vol. 126, (21)

Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V, Ahluwalia A(2012). Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP. CIRCULATION vol. 126, (21)

Bubb KJ, Khambata RS, Ahluwalia A(2012). Sexual dimorphism in rodent models of hypertension and atherosclerosis. Br J Pharmacol vol. 167, (2) 298-312.

Khambata R, Ghosh S, Ahluwalia A (2012). Nitrite superfusion reduces leukocyte-endothelial interactions in the mouse cremaster model. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 27, S15-S15.

Khambata RS, Panayiotou CM, Hobbs AJ(2011). Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide. Br J Pharmacol vol. 164, (2b) 584-597.

Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ et al.(2011). Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol vol. 31, (5) 1075-1083.

Lumsden NG, Khambata RS, Hobbs AJ(2010). C-type Natriuretic Peptide (CNP): Cardiovascular Roles and Potential as a Therapeutic Target. CURRENT PHARMACEUTICAL DESIGN vol. 16, (37) 4080-4088.

Khambata RS, Panayiotou CM, Xiao F, Hobbs AJ(2010). The anti-atherogenic potential of C-type natriuretic peptide: Disparate regulation of endothelial and vascular smooth muscle cell proliferation via natriuretic peptide receptor-C. FASEB JOURNAL vol. 24,

Lumsden NG, Khambata RS, Hobbs AJ(2010). C-type natriuretic peptide (CNP): cardiovascular roles and potential as a therapeutic target. Curr Pharm Des vol. 16, (37) 4080-4088.