Publications: Prof Angray Kang
Chance R, Kang AS
(
2024
)
.
Eukaryotic ribosome display for antibody discovery: A review
.
Human Antibodies
vol.
32
,
(
3
)
107
-
120
.
Neunie OAM, Rabbani W, Baker D, Chambers ES, Pfeffer PE, Kang AS
(
2024
)
.
Immunogenicity of biologics used in the treatment of asthma
.
Human Antibodies
vol.
32
,
(
3
)
121
-
128
.
Baker D, Kang AS, Giovannoni G, Schmierer K
(
2023
)
.
Neutropenia following immune-depletion, notably CD20 targeting, therapies in multiple sclerosis
.
Multiple Sclerosis and Related Disorders
vol.
82
,
Dobson R
(
2023
)
.
Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination
.
Multiple Sclerosis Journal
Frankling CL, Downes MF, Kang AS, Main ERG
(
2023
)
.
Exploring the ‘N-terminal arm’ & ‘Convex surface’ Binding Interfaces of the T3SS Chaperone-Translocator Complexes from P. Aeruginosa
.
Journal of Molecular Biology
vol.
435
,
(
15
)
Frankling CL, Kang AS, Main ERG
(
2023
)
.
Exploring the “N-Terminal Anchor” Binding Interface of the T3SS Chaperone–Translocator Complexes from P. aeruginosa
.
Biochemistry
vol.
62
,
(
8
)
1420
-
1427
.
Baker D, Forte E, Pryce G, Kang AS, James LK, Giovannoni G, Schmierer K
(
2022
)
.
The impact of sphingosine-1-phosphate receptor modulators on COVID-19 and SARS-CoV-2 vaccination
.
Multiple Sclerosis and Related Disorders
vol.
69
,
Tallantyre EC, Scurr MJ, Vickaryous N, Richards A, Anderson V, Baker D, Chance R, Evangelou N et al.
(
2022
)
.
Response to COVID-19 booster vaccinations in seronegative people with multiple sclerosis
.
Multiple Sclerosis and Related Disorders
vol.
64
,
Baker D, MacDougall A, Kang AS, Schmierer K, Giovannoni G, Dobson R
(
2022
)
.
Seroconversion following COVID-19 vaccination: can we optimize protective response in CD20-treated individuals?
.
Clin Exp Immunol
vol.
207
,
(
3
)
263
-
271
.
Vickaryous N, Rios F, Schalk L, Asardag AN, George K, Kang A, Baker D, Giovannoni G et al.
(
2022
)
.
COVID-19 humoral and T-cell mediated vaccination responses in people with multiple sclerosis
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
28
,
680
-
680
.
Upcott M, Tallantyre EC, Scurr MJ, Vickaryous N, Richards A, Anderson V, Baker D, Chance R et al.
(
2022
)
.
Humoral and T- cell response to multiple COVID-19 booster vaccinations in people with MS
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
28
,
365
-
366
.
Baker D
(
2021
)
.
CD19 B cell repopulation after ocrelizumab, alemtuzumab and cladribine: Implications for SARS-CoV-2 vaccinations in multiple sclerosis
.
Multiple Sclerosis and Related Disorders
Dobson R, Baker D, Kang A, Schmierer K, Giovannoni G
(
2021
)
.
COVID-19 vaccine response in people with multiple sclerosis
.
Annals of Neurology
Baker D, Asardag AN, Quinn OA, Efimov A, Kang AS
(
2021
)
.
Anti-drug antibodies to antibody-based therapeutics in multiple sclerosis
.
Hum Antibodies
Patel V, Efimov A, Baker D, Kang AS
(
2021
)
.
Immunogenicity of biologics used in the treatment of moderate to severe psoriasis
.
Human Antibodies
vol.
29
,
(
3
)
171
-
178
.
Bqain M, Efimov A, Baker D, Kang AS
(
2021
)
.
Immunogenicity of biologics used in the treatment of inflammatory bowel disease: A review
.
Human Antibodies
Vickaryous N, Asardag AN, Chance R, Jones M, Bestwick J, Shah SN, George K, Schmierer K et al.
(
2021
)
.
Seroconversion following vaccination against SARS-CoV-2 in people with MS: impact of disease modifying therapy
.
MULTIPLE SCLEROSIS JOURNAL
vol.
27
,
(
2_SUPPL
)
775
-
776
.
Baker D, Roberts CAK, Pryce G, Kang AS, Marta M, Reyes S, Schmierer K, Giovannoni G et al.
(
2020
)
.
COVID-19 vaccine-readiness for anti-CD20-depleting therapy in autoimmune diseases
.
Clinical and Experimental Immunology
vol.
202
,
(
2
)
149
-
161
.
Senusi A, Kang A, Buchanan JAG, Adesanya A, Aloraini G, Stanford M, Fortune F
(
2020
)
.
New mouthwash: an efficacious intervention for oral ulceration associated with Behçet's disease
.
British Journal of Oral and Maxillofacial Surgery
vol.
58
,
(
8
)
1034
-
1039
.
Li J, Wang J, Kang AS, Sacitharan PK
(
2020
)
.
Mapping the T cell response to COVID-19
.
Signal Transduction and Targeted Therapy
vol.
5
,
(
1
)
Saxena G, Moore JM, Jones M, Pryce G, Ali L, Leisegang GR, Vijay V, Loveless S et al.
(
2020
)
.
Detecting and predicting neutralization of alemtuzumab responses in MS
.
Neurology Neuroimmunology & Neuroinflammation
vol.
7
,
(
4
)
Baker D, Amor S, Kang AS, Schmierer K, Giovannoni G
(
2020
)
.
The underpinning biology relating to multiple sclerosis disease modifying treatments during the COVID-19 pandemic
.
Multiple Sclerosis and Related Disorders
vol.
43
,
Munger K, Kang A, Baker D, Goodman A, Samkoff L
(
2020
)
.
Alemtuzumab Depletion Failure and Neutralizing Anti-Drug Antibodies: a Case Report and Call for Monitoring (1347)
.
Neurology
vol.
94
,
(
15_supplement
)
Jiang Y, Yi C, Yi Y, Jin Q, Kang AS, Li J, Kumar Sacitharan P
(
2020
)
.
Adiponectin exacerbates influenza infection in elderly individuals via IL-18
.
Signal Transduct Target Ther
vol.
5
,
(
1
)
Houacine S, Kang A, Parkinson EK, Wan H, Fortune F
(
2020
)
.
Induction of p53 in keratinocyte cultures treated with Behçet's patient sera
.
Journal of Oral Pathology and Medicine
vol.
49
,
(
5
)
435
-
442
.
Ali L, SAXENA G, Jones M, Leisegang G, Gammon L, Gnanapavan S, Giovannoni G, Schmierer K et al.
(
2020
)
.
A cell-based assay for the detection of neutralizing antibodies against alemtuzumab
.
BioTechniques: the journal of laboratory technology for bioresearch
Baker D, Ali L, SAXENA G, Pryce G, Jones M, Schmierer K, Giovannoni G, Gnanapavan S et al.
(
2020
)
.
The irony of humanization: Alemtuzumab the first, but one of the most immunogenic, humanized monoclonal antibodies
.
Frontiers in Immunology
vol.
11
,
(
124
)
Saxena GK, Theocharopoulos I, Aziz NT, Jones M, Gnanapavan S, Giovannoni G, Schmierer K, Garnett JA et al.
(
2020
)
.
GloBody Technology: Detecting Anti-Drug Antibody against VH/VL domains
.
Scientific Reports
vol.
10
,
(
1
)
Article
1860
,
Munger K, Kang A, Baker D, Goodman A, Samkoff L
(
2020
)
.
Alemtuzumab depletion failure and neutralizing anti-drug antibodies: a case report and call for monitoring
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
26
,
258
-
258
.
Uttagomol J, Ahmad US, Rehman A, Huang Y, Laly AC, Kang A, Soetaert J, Chance R et al.
(
2019
)
.
Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces
.
International Journal of Molecular Sciences
vol.
20
,
(
24
)
Rehman A, Cai Y, Hünefeld C, Jedličková H, Huang Y, Teck Teh M, Sharif Ahmad U, Uttagomol J et al.
(
2019
)
.
The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53
.
Cell Death & Disease
vol.
10
,
(
10
)
Dubuisson N, Baker D, Kang AS, Pryce G, Marta M, Visser LH, Hofmann WE, Gnanapavan S et al.
(
2018
)
.
Alemtuzumab depletion failure can occur in multiple sclerosis
.
Immunology
vol.
154
,
(
2
)
253
-
260
.
Baker D, Kang AS, Gnanapavan S, Giovannoni G, Schmierer K
(
2017
)
.
A central role of B cells in MS control and causing autoimmunity after alemtuzumab
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
23
,
336
-
336
.
Sylejmani G, Gupta A, Cheng Q, Kang A, Durvasula R, Hurwitz I
(
2014
)
.
DEVELOPMENT OF RECOMBINANT ANTIBODIES TO COMBAT CLOSTRIDIUM DIFFICILE INFECTION
.
JOURNAL OF INVESTIGATIVE MEDICINE
.
vol.
62
,
229
-
229
.
Tang J, Wang L, Markiv A, Jeffs SA, Dreja H, McKnight A, He M, Kang AS
(
2012
)
.
Accessing of recombinant human monoclonal antibodies from patient libraries by eukaryotic ribosome display
.
Human Antibodies
vol.
21
,
(
1-2
)
1
-
11
.
Ujor VC, Peiris DG, Monti M, Kang AS, Clements MO, Hedger JN
(
2012
)
.
Quantitative proteomic analysis of the response of the wood-rot fungus, Schizophyllum commune, to the biocontrol fungus, Trichoderma viride
.
Lett Appl Microbiol
vol.
54
,
(
4
)
336
-
343
.
Hurwitz I, Fieck A, Klein N, Jose C, Kang A, Durvasula R
(
2012
)
.
A paratransgenic strategy for the control of chagas disease
.
Psyche (London)
Azizi A, Arora A, Markiv A, Lampe DJ, Miller TA, Kang AS
(
2012
)
.
Ribosome Display of Combinatorial Antibody Libraries Derived from Mice Immunized with Heat-Killed <i>Xylella fastidiosa</i> and the Selection of MopB-Specific Single-Chain Antibodies
.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
vol.
78
,
(
8
)
2638
-
2647
.
Markiv A, Beatson R, Burchell J, Durvasula RV, Kang AS
(
2011
)
.
Expression of recombinant multi-coloured fluorescent antibodies in gor -/trxB- E. coli cytoplasm
.
BMC Biotechnol
vol.
11
,
Tsimon M, Kang A, Markiv A, Kousparou C, Epenetos A
(
2011
)
.
Abstract 4441: Intracellular delivery of therapeutic siRNA via an antennapedia-RNA-binding domain fusion peptide
.
Cancer Research
vol.
71
,
(
8_Supplement
)
4441
-
4441
.
Fang W, Vega-Rodríguez J, Ghosh AK, Jacobs-Lorena M, Kang A, St Leger RJ
(
2011
)
.
Development of transgenic fungi that kill human malaria parasites in mosquitoes
.
Science
vol.
331
,
(
6020
)
1074
-
1077
.
Markiv A, Anani B, Durvasula RV, Kang AS
(
2011
)
.
Module based antibody engineering: a novel synthetic REDantibody
.
J Immunol Methods
vol.
364
,
(
1-2
)
40
-
49
.
Jacobs-Lorena M, Wang S, Lampe D, Fang W, Vega-Rodriguez J, Ghosh A, Kang A, Leger RS
(
2011
)
.
Fighting malaria with engineered fungi and bacteria
.
TROPICAL MEDICINE & INTERNATIONAL HEALTH
.
vol.
16
,
9
-
+
.
Hurwitz I, Fieck A, Read A, Hillesland H, Klein N, Kang A, Durvasula R
(
2011
)
.
Paratransgenic control of vector borne diseases
.
Int J Biol Sci
vol.
7
,
(
9
)
1334
-
1344
.
Damiani C, Ricci I, Crotti E, Rossi P, Rizzi A, Scuppa P, Capone A, Ulissi U et al.
(
2010
)
.
Mosquito-bacteria symbiosis: the case of Anopheles gambiae and Asaia
.
Microb Ecol
vol.
60
,
(
3
)
644
-
654
.
Fieck A, Hurwitz I, Kang AS, Durvasula R
(
2010
)
.
Trypanosoma cruzi: synergistic cytotoxicity of multiple amphipathic anti-microbial peptides to T. cruzi and potential bacterial hosts
.
Exp Parasitol
vol.
125
,
(
4
)
342
-
347
.
Nguyen TV, Sacci JB, de la Vega P, John CC, James AA, Kang AS
(
2009
)
.
Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals
.
Malar J
vol.
8
,
Stura EA, Kang AS, Stefanko RS, Calvo JC, Kaslow DC, Satterthwait AC
(
2007
)
.
Crystallization, sequence and preliminary crystallographic data for transmission‐blocking anti‐malaria Fab 4B7 with cyclic peptides from the Pfs25 protein of P. falciparum
.
Acta Crystallographica Section D, Structural Biology
vol.
50
,
(
4
)
535
-
542
.
Morgan MRA, Kang AS, Chan HW
(
2006
)
.
Aflatoxin determination in peanut butter by enzyme‐linked immunosorbent assay
.
Journal of the Science of Food and Agriculture
vol.
37
,
(
9
)
908
-
914
.
Murphy DJ, Cummins I, Kang AS
(
2006
)
.
Immunocytochemical and biochemical studies of the mobilisation of storage oil‐bodies and proteins in germinating cotyledons of oilseed rape, Brassica napus
.
Journal of the Science of Food and Agriculture
vol.
48
,
(
2
)
209
-
223
.
Murphy DJ, Cummins I, Kang AS
(
2006
)
.
Immunological investigation of lipases in germinating oilseed rape, Brassica napus
.
Journal of the Science of Food and Agriculture
vol.
47
,
(
1
)
21
-
31
.
Morgan MRA, Kang AS, Chan HW
(
2006
)
.
Production of antisera against sterigmatocystin hemiacetal and its potential for use in an enzyme‐linked immunosorbent assay for sterigmatocystin in barley
.
Journal of the Science of Food and Agriculture
vol.
37
,
(
9
)
873
-
880
.
Peterson JW, Comer JE, Noffsinger DM, Wenglikowski A, Walberg KG, Chatuev BM, Chopra AK, Stanberry LR et al.
(
2006
)
.
Human Monoclonal Anti-Protective Antigen Antibody Completely Protects Rabbits and Is Synergistic with Ciprofloxacin in Protecting Mice and Guinea Pigs against Inhalation Anthrax
.
Infection and Immunity
vol.
74
,
(
2
)
1016
-
1024
.
Stratmann T, Kang AS
(
2005
)
.
Cognate peptide-receptor ligand mapping by directed phage display
.
Proteome Science
vol.
3
,
(
1
)
Cote CK, Rossi CA, Kang AS, Morrow PR, Lee JS, Welkos SL
(
2005
)
.
The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions
.
Microbial Pathogenesis
vol.
38
,
(
5-6
)
209
-
225
.
Cote CK, Rossi CA, Kang AS, Morrow PR, Lee JS, Welkos SL
(
2005
)
.
The Detection of Protective Antigen (PA) Associated with Spores of Bacillus Anthracis and the Effects of Anti-PA Antibodies on Spore Germination and Macrophage Interactions
.
Chappel JA, Rogers WO, Hoffman SL, Kang AS
(
2004
)
.
Molecular dissection of the human antibody response to the structural repeat epitope of Plasmodium falciparum sporozoite from a protected donor
.
Malaria Journal
vol.
3
,
(
1
)
Sawada-Hirai R, Jiang I, Wang F, Sun SM, Nedellec R, Ruther P, Alvarez A, Millis D et al.
(
2004
)
.
Human anti-anthrax protective antigen neutralizing monoclonal antibodies derived from donors vaccinated with anthrax vaccine adsorbed
.
Journal of Immune Based Therapies and Vaccines
vol.
2
,
(
1
)
Wang F, Ruther P, Jiang I, Sawada-Hirai R, Sun SM, Nedellec R, Morrow PR, Kang AS
(
2004
)
.
Human monoclonal antibodies that neutralize anthrax toxin by inhibiting heptamer assembly
.
Human Antibodies
vol.
13
,
(
4
)
105
-
110
.
Chappel JA, Hollingdale MR, Kang AS
(
2004
)
.
IgG 4 Pf NPNA-1 a human anti-Plasmodium falciparum sporozoite monoclonal antibody cloned from a protected individual inhibits parasite invasion of hepatocytes
.
Human Antibodies
vol.
13
,
(
3
)
91
-
96
.
Durvasula RV, Gumbs A, Panackal A, Kruglov O, Taneja J, Kang AS, Cordon‐Rosales C, Richards FF et al.
(
2002
)
.
Expression of a functional antibody fragment in the gut of Rhodnius prolixus via transgenic bacterial symbiont Rhodococcus rhodnii
.
Medical and Veterinary Entomology
vol.
13
,
(
2
)
115
-
119
.
Nguyen TV, Fujioka H, Kang AS, Rogers WO, Fidock DA, James AA
(
2001
)
.
Stage-dependent Localization of a Novel Gene Product of the Malaria Parasite, Plasmodium falciparum *
.
Journal of Biological Chemistry
vol.
276
,
(
28
)
26724
-
26731
.
Stratmann T, Apostolopoulos V, Mallet-Designe V, Corper AL, Scott CA, Wilson IA, Kang AS, Teyton L
(
2000
)
.
The I-Ag7 MHC Class II Molecule Linked to Murine Diabetes Is a Promiscuous Peptide Binder
.
The Journal of Immunology
vol.
165
,
(
6
)
3214
-
3225
.
Corper AL, Stratmann T, Apostolopoulos V, Scott CA, Garcia KC, Kang AS, Wilson IA, Teyton L
(
2000
)
.
A Structural Framework for Deciphering the Link Between I-Ag7 and Autoimmune Diabetes
.
Science
vol.
288
,
(
5465
)
505
-
511
.
Lode HN, Dreier T, Xiang R, Varki NM, Kang AS, Reisfeld RA
(
2000
)
.
Erratum: Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma (Proceedings of the National Academy of Sciences of the United States of America (March 3, 1998) 95:5 (2475-2480))
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
97
,
(
7
)
Chappel JA, He M, Kang AS
(
1998
)
.
Modulation of antibody display on M13 filamentous phage
.
Journal of Immunological Methods
vol.
221
,
(
1-2
)
25
-
34
.
Dreier T, Lode HN, Xiang R, Dolman CS, Reisfeld RA, Kang AS
(
1998
)
.
Recombinant Immunocytokines Targeting the Mouse Transferrin Receptor: Construction and Biological Activities
.
Bioconjugate Chemistry
vol.
9
,
(
4
)
482
-
489
.
Lode HN, Dreier T, Xiang R, Varki NM, Kang AS, Reisfeld RA
(
1998
)
.
Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
95
,
(
5
)
2475
-
2480
.
Stratmann T, Schmid SR, Harper JF, Kang AS
(
1997
)
.
Bacterial Expression and Purification of RecombinantPlasmodium yoeliiCircumsporozoite Protein
.
Protein Expression and Purification
vol.
11
,
(
1
)
72
-
78
.
Mason P, Berinstein A, Baxt B, Parsells R, Kang A, Rieder E
(
1996
)
.
Cloning and Expression of a Single-Chain Antibody Fragment Specific for Foot-and-Mouth Disease Virus
.
Virology
vol.
224
,
(
2
)
548
-
554
.
Rieder E, Berinstein A, Baxt B, Kang A, Mason PW
(
1996
)
.
Propagation of an attenuated virus by design: engineering a novel receptor for a noninfectious foot-and-mouth disease virus
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
93
,
(
19
)
10428
-
10433
.
He M, Hamon M, Liu H, Kang A, Taussig MJ
(
1995
)
.
Functional expression of a single-chain anti-progesterone antibody fragment in the cytoplasm of a mutant Escherichia coil
.
Nucleic Acids Research
vol.
23
,
(
19
)
4009
-
4010
.
He M, Kang AS, Hamon M, Humphreys AS, Gani M, Taussig MJ
(
1995
)
.
Characterization of a progesterone-binding, three-domain antibody fragment (VH/K) expressed in Escherichia coli
.
Immunology
vol.
84
,
(
4
)
662
-
668
.
Lerner RA, Kang AS, Bain JD, Burton DR, Barbas CF
(
1992
)
.
Antibodies Without Immunization
.
Science
vol.
258
,
(
5086
)
1313
-
1314
.
Gram H, Marconi LA, Barbas CF, Collet TA, Lerner RA, Kang AS
(
1992
)
.
In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
89
,
(
8
)
3576
-
3580
.
Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA
(
1992
)
.
Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. 1989
.
Biotechnology
vol.
24
,
517
-
523
.
Kang AS, Jones TM, Burton DR
(
1991
)
.
Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
88
,
(
24
)
11120
-
11123
.
Lerner RA, Barbas CF, Kang AS, Burton DR
(
1991
)
.
On the use of combinatorial antibody libraries to clone the "fossil record" of an individual's immune response
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
88
,
(
21
)
9705
-
9706
.
Barbas CF, Kang AS, Lerner RA, Benkovic SJ
(
1991
)
.
Assembly of combinatorial antibody libraries on phage surfaces: the gene III site
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
88
,
(
18
)
7978
-
7982
.
Kang AS, Barbas CF, Janda KD, Benkovic SJ, Lerner RA
(
1991
)
.
Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
88
,
(
10
)
4363
-
4366
.
Kang AS, Burton DR, Lerner RA
(
1991
)
.
Combinatorial immunoglobulin libraries in phage λ
.
Methods
vol.
2
,
(
2
)
111
-
118
.
Kang AS, Kingsbury GA, Blackburn GM, Burton DR
(
1990
)
.
Catalytic antibodies. Designer enzymes
.
Chemistry in Britain
vol.
26
,
(
2
)
128
-
132
.
Field H, Yeung HLH, Rees AR, Bagshawe KD, Kang AS, Burton DR, Blackburn GM, Hill CR et al.
(
1990
)
.
New applications for antibodies
.
Analytical Proceedings
.
vol.
27
,
2
-
15
.
Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA
(
1989
)
.
Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda
.
Science
vol.
246
,
(
4935
)
1275
-
1281
.
Au DMY, Kang AS, Murphy DJ
(
1989
)
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An immunologically related family of apolipoproteins associated with triacylglycerol storage in the Cruciferae
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