Publications:  Prof Andrew Tinker

Ntalla I, Weng LC, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD et al.(2020). Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nature Communications vol. 11, (1)

Aziz Q, Chen J, Moyes AJ, Li Y, Anderson NA, Ang R, Aksentijevic D, Sebastian S et al.(2020). Vascular KATP channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia. Journal of Molecular Medicine

Villar D, Frost S, Deloukas P, Tinker A(2020). The contribution of non-coding regulatory elements to cardiovascular disease. Open biology vol. 10, (7)

van Duijvenboden S, Ramírez J, Young WJ, Mifsud B, Orini M, Tinker A, Munroe PB, Lambiase PD(2020). Genetic Basis and Prognostic Value of Exercise QT Dynamics. Circ Genom Precis Med

Williams JL, Paudyal A, Awad S, Nicholson J, Grzesik D, Botta J, Meimaridou E, Maharaj AV et al.(2020). Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not. Life science alliance vol. 3, (4)

Ramírez J, van Duijvenboden S, Young WJ, Orini M, Lambiase PD, Munroe PB, Tinker A(2020). Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval. American Journal of Human Genetics

Balestrini S, Mikati M, Garcia-Roves RA, Carboni M, Hunanyan A, Kherallah B, McLean M, Prange L et al. (2019). Cardiac Phenotype In ATP1A3 Related-Syndromes: A Multicentre Study. EPILEPSIA. vol. 60, 173-173.

Ramírez J, van Duijvenboden S, Aung N, Laguna P, Pueyo E, Tinker A, Lambiase PD, Orini M et al.(2019). Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. Circulation: Arrhythmia and Electrophysiology vol. 12, (10) e007549-e007549.

Cartwright JH, Aziz Q, Harmer SC, Thayyil S, Tinker A, Munroe PB(2019). Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function. Hum Mol Genet

Thomas AM, Cabrera CP, Finlay M, Lall K, Nobles M, Schilling RJ, Wood K, Mein CA et al.(2019). Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages. Physiol Genomics vol. 51, (8) 323-332.

Finlay M, Bhar-Amato J, Ng K-E, Santos D, Orini M, Vyas V, Taggart P, Grace AA et al.(2019). Autonomic modulation of the electrical substrate in mice haploinsufficient for cardiac sodium channels: a model of the Brugada syndrome. Am J Physiol Cell Physiol

Ramirez J, van Duijvenboden S, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al. (2019). Identification of novel loci for heart rate response to exercise and recovery. EUROPEAN JOURNAL OF HUMAN GENETICS. vol. 27, 135-135.

Noordam R, Young WJ, Salman R, Kanters JK, van den Berg ME, van Heemst D, Lin HJ, Barreto SM et al.(2019). Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. Journal of the American College of Cardiology vol. 73, (24) 3118-3131.

van Duijvenboden S, Ramirez J, Orini M, Tinker A, Munroe PB, Lambiase P (2019). CARDIAC REPOLARIZATION DURING EXERCISE REVEALS INDEPENDENT PROGNOSTIC INFORMATION FOR CARDIOVASCULAR RISK PREDICTION. HEART. vol. 105, A19-A20.

Honarbakhsh S, Hunter RJ, Finlay M, Ullah W, Keating E, Tinker A, Schilling RJ(2019). Development, in vitro validation and human application of a novel method to identify arrhythmia mechanisms: The stochastic trajectory analysis of ranked signals mapping method. J Cardiovasc Electrophysiol vol. 30, (5) 691-701.

Maruthappu T, Posafalvi A, Castelletti S, Delaney PJ, Syrris P, O'Toole EA, Green KJ, Elliott PM et al.(2019). Loss-of-function desmoplakin I and II mutations underlie dominant arrhythmogenic cardiomyopathy with a hair and skin phenotype. British Journal of Dermatology vol. 180, (5) 1114-1122.

Ramirez J, van Duijvenboden S, Tinker A, Lambiase P, Orini M, Munroe PB (2019). THE CARDIOVASCULAR PREDICTIVE VALUE AND GENETIC BASIS OF T-WAVE MORPHOLOGY. HEART. vol. 105, A18-A19.

Zhou X, Bueno-Orovio A, Schilling RJ, Kirkby C, Denning C, Rajamohan D, Burrage K, Tinker A et al.(2019). Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D. Front Physiol vol. 10, 259-259.

Mosqueira D, Mannhardt I, Bhagwan JR, Lis-Slimak K, Katili P, Scott E, Hassan M, Prondzynski M et al. (2019). CRISPR/Cas9 genome editing in human pluripotent stem cell-cardiomyocytes provides a platform for modeling hypertrophic cardiomyopathy. HUMAN GENE THERAPY. vol. 30, A5-A5.

Scott ES, Awford J, Hyde R, Hassan M, Hashmi L, Harmer S, Fischer P, Kellam B et al. (2019). Using bioluminescent hiPSC reporter lines and high content screening to identify novel compounds for cardiomyocyte maturation. HUMAN GENE THERAPY. vol. 30, A8-A8.

Mosqueira D, Mannhardt I, Bhagwan JR, Lis-Slimak K, Katili P, Scott E, Hassan M, Prondzynski M et al. (2018). CRISPR/Cas9 gene editing in human pluripotent stem cell-cardiomyocytes provides a platform for modeling hypertrophic cardiomyopathy. HUMAN GENE THERAPY. vol. 29, A93-A94.

Arcidiacono P, Webb CM, Brooke MA, Zhou H, Delaney PJ, Ng KE, Blaydon DC, Tinker A et al.(2018). P63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response. Nature Communications vol. 9, (1)

Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al.(2018). Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. Nature Communications vol. 9, (1)

Mosqueira D, Mannhardt I, Bhagwan JR, Lis-Slimak K, Katili P, Scott E, Hassan M, Prondzynski M et al.(2018). CRISPR/Cas9 editing in human pluripotent stemcell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy. European Heart Journal vol. 39, (43) 3879-3892.

Ang R, Mastitskaya S, Hosford PS, Basalay M, Specterman M, Aziz Q, Li Y, Orini M et al.(2018). Modulation of Cardiac Ventricular Excitability by GLP-1 (Glucagon-Like Peptide-1). Circ Arrhythm Electrophysiol vol. 11, (10) e006740-e006740.

Calmont A, Anderson N, Suntharalingham JP, Ang R, Tinker A, Scambler PJ(2018). Defective Vagal Innervation in Murine Tbx1 Mutant Hearts. J Cardiovasc Dev Dis vol. 5, (4)

Bhar-Amato J, Finlay M, Santos D, Orini M, Chaubey S, Vyas V, Taggart P, Grace AA et al.(2018). Pharmacological Modulation of Right Ventricular Endocardial-Epicardial Gradients in Brugada Syndrome. Circ Arrhythm Electrophysiol vol. 11, (9) e006330-e006330.

Ramirez J, Van Duijvenboden S, Laguna P, Pueyo E, Tinker A, Lambiase PD, Munroe PB, Orini M (2018). Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology. Computing in Cardiology. Conference: Computing in Cardiology (Maastricht, The Netherlands) from: 23/09/2018 to: 26/09/2018, vol. 2018-September,

Castelletti S, Maruthappu T, Posafalvi A, Syrris P, O'Toole EA, Green KJ, Tinker A, McKenna WJ et al. (2018). Hair and cutaneous phenotypes linked to Arrhythmogenic Cardiomyopathy caused by Desmoplakin haploinsufficiency: an additional disease marker. EUROPEAN HEART JOURNAL. vol. 39, 1206-1206.

Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J et al.(2018). Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biology vol. 19, (1)

Aziz Q, Finlay M, Montaigne D, Ojake L, Li Y, Anderson N, Ludwig A, Tinker A(2018). ATP-sensitive potassium channels in the sinoatrial node contribute to heart rate control and adaptation to hypoxia. Journal of Biological Chemistry vol. 293, (23) 8912-8921.

Hosford PS, Christie IN, Niranjan A, Aziz Q, Anderson N, Ang R, Lythgoe MF, Wells JA et al.(2018). A critical role for the ATP-sensitive potassium channel subunit KIR6.1 in the control of cerebral blood flow. Journal of Cerebral Blood Flow and Metabolism

Nobles M, Montaigne D, Sebastian S, Birnbaumer L, Tinker A(2018). Differential effects of inhibitory G protein isoforms on G protein-gated inwardly rectifying K+ currents in adult murine atria. Am J Physiol Cell Physiol vol. 314, (5) C616-C626.

Tinker A, Finlay M, Nobles M, Opel A(2018). Erratum to "The contribution of pathways initiated via the Gq\11 G-protein family to atrial fibrillation" [Pharmacol. Res. 105 (2016) 54-61]. Pharmacol Res vol. 129,

Lovering RC, Roncaglia P, Howe DG, Laulederkind SJF, Khodiyar VK, Berardini TZ, Tweedie S, Foulger RE et al.(2018). Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology. Circ Genom Precis Med vol. 11, (2) e001813-e001813.

Orini M, Tinker A, Munroe PB, Lambiase PD(2018). Correction: Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort. PLoS One vol. 13, (2) e0193039-e0193039.

Tinker A, Aziz Q, Li Y, Specterman M(2018). ATP-sensitive potassium channels and their physiological and pathophysiological roles. Comprehensive Physiology vol. 8, (4) 1463-1511.

Munroe PB, Addison S, Abrams DJ, Sebire NJ, Cartwright J, Donaldson I, Cohen MM, Mein C et al.(2018). Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths. Circulation. Genomic and precision medicine vol. 11, (1)

Aziz Q, Li Y, Tinker A(2018). Potassium channels in the sinoatrial node and their role in heart rate control. Channels vol. 12, (1) 356-366.

Aziz Q, Li Y, Tinker A(2017). Endothelial biology and ATP-sensitive potassium channels. Channels1-2.

Miller DC, Harmer SC, Poliandri A, Nobles M, Edwards EC, Ware JS, Sharp TV, McKay TR et al.(2017). Ajmaline blocks I<inf>Na</inf> and I<inf>Kr</inf> without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters. Stem Cell Research vol. 25, 233-244.

TINKER A, Lane J D(2017). Have the Findings from Clinical Risk Prediction and Trials Any Key Messages for Safety Pharmacology?. Frontiers in Physiology vol. 8,

Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV et al.(2017). Mammalian γ2 AMPK regulates intrinsic heart rate. Nat Commun vol. 8, (1) 1258-1258.

Aziz Q, Li Y, Anderson N, Ojake L, Tsisanova E, Tinker A(2017). Molecular and functional characterization of the endothelial ATP-sensitive potassium channel. Journal of Biological Chemistry vol. 292, (43) 17587-17597.

Royal AA, Tinker A, Harmer SC(2017). Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking. PLoS One vol. 12, (10) Article 0186293, e0186293-e0186293.

Lane JD, Montaigne D, Tinker A (2017). Tissue-Level Cardiac Electrophysiology Studied in Murine Myocardium Using a Microelectrode Array: Autonomic and Thermal Modulation. United States , vol. 250, is. 5, pp. 471-481. Abstract: java.sql.Clob org.hibernate.engine.jdbc.WrappedClob java.io.Serializable ,

Orini M, Tinker A, Munroe PB, Lambiase PD(2017). Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort. PLoS One vol. 12, (9) e0183732-e0183732.

Tinker A(2017). The mechanisms of ventricular arrhythmia in Chagas disease. Int J Cardiol vol. 240, 372-373.

Munroe PB, Tinker A(2017). Heritability of resting heart rate and association with mortality in middle-aged and elderly twins. Heart vol. 104, (1) 6-7.

Finlay M, Harmer SC, Tinker A(2017). The control of cardiac ventricular excitability by autonomic pathways. Pharmacology and Therapeutics vol. 174, 97-111.

Poliandri A, Miller D, Howard S, Nobles M, Ruiz-Babot G, Harmer S, Tinker A, McKay T et al.(2017). Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells. Molecular and Cellular Endocrinology vol. 447, 12-22.

Cartwright J, Aziz Q, Harmer S, Tinker A, Munroe P (2017). Functional Studies of TRPM7-a Candidate Gene for Stillbirth?. FASEB JOURNAL. Conference: EB vol. 31,

MUNROE PB, Caulfield M, Stirrups K, van den Berg M, Warren H, Cabrera CP(2017). Discovery of novel heart rate-associated loci using the exome chip. Human Molecular Genetics

MUNROE PB(2016). Trans-ancestry meta-analyses identify novel rare and common variants associated with blood pressure and hypertension. Nature Genetics

Ang R, Abramowitz J, Birnbaumer L, Gourine AV, Tinker A(2016). The role of GαO-mediated signaling in the rostral ventrolateral medulla oblongata in cardiovascular reflexes and control of cardiac ventricular excitability. Physiol Rep vol. 4, (15)

Ishida H, Saba R, Kokkinopoulos I, Hashimoto M, Yamaguchi O, Nowotschin S, Shiraishi M, Ruchaya P et al.(2016). GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway. Cell Rep vol. 16, (4) 1026-1038.

Ang R, Abramowitz J, Birnbaumer L, Gourine AV, Tinker A (2016). Loss of the inhibitory GalphaO protein in the rostral ventrolateral medulla of the brainstem leads to abnormalities in cardiovascular reflexes and altered ventricular excitablitiy. CARDIOVASCULAR RESEARCH. Conference: ESC meeting vol. 111, S98-S98.

Tinker A, Finlay M, Nobles M, Opel A(2016). The contribution of pathways initiated via the Gq\11 G-protein family to atrial fibrillation. Pharmacol Res vol. 105, 54-61.

Harmer SC, Tinker A(2016). The impact of recent advances in genetics in understanding disease mechanisms underlying the long QT syndromes. Biol Chem vol. 397, (7) 679-693.

Rodriguez B, Carusi A, Abi-Gerges N, Ariga R, Britton O, Bub G, Bueno-Orovio A, Burton RAB et al.(2016). Human-based approaches to pharmacology and cardiology: An interdisciplinary and intersectorial workshop. Europace vol. 18, (9) 1287-1298.

Richards DA, Fletcher SA, Nobles M, Kossen H, Tedaldi L, Chudasama V, Tinker A, Baker JR(2016). Photochemically re-bridging disulfide bonds and the discovery of a thiomaleimide mediated photodecarboxylation of C-terminal cysteines. Organic and Biomolecular Chemistry vol. 14, (2) 455-459.

Munroe PB, Tinker A(2015). Genome-wide association studies and contribution to cardiovascular physiology. Physiological Genomics vol. 47, (9) 365-375.

Fletcher SA, Sin PKB, Nobles M, Årstad E, Tinker A, Baker JR(2015). A dual optical and nuclear imaging reagent for peptide labelling via disulfide bridging. Organic and Biomolecular Chemistry vol. 13, (37) 9559-9563.

Machhada A, Ang R, Ackland G, Ninkina N, Buchman V, Lythgoe MF, Trapp S, Tinker A et al. (2015). Reduced activity of dorsal vagal preganglionic neurones associated with synuclein pathology predisposes the heart to ventricular arrhythmia. EUROPEAN HEART JOURNAL. vol. 36, 215-215.

Opel A, Nobles M, Montaigne D, Finlay M, Anderson N, Breckenridge R, Tinker A(2015). Absence of the Regulator of G-protein Signaling, RGS4, Predisposes to Atrial Fibrillation and Is Associated with Abnormal Calcium Handling. J Biol Chem vol. 290, (31) 19233-19244.

Lambiase PD, Tinker A(2015). Connexins in the heart. Cell Tissue Res vol. 360, (3) 675-684.

Yeoh A, Finlay M, Anderson N, Harmer S, Tinker A (2015). SIMULTANEOUS MEASUREMENT OF CALCIUM TRANSIENTS AND ELECTRICAL ACTIVITY IN MURINE CARDIAC TISSUE - A NOVEL SYSTEM FOR THE STUDY OF CARDIAC ARRHYTHMIA. HEART. vol. 101, A92-A93.

Nessa A, Aziz QH, Thomas AM, Harmer SC, Tinker A, Hussain K(2015). Molecular mechanisms of congenital hyperinsulinism due to autosomal dominant mutations in ABCC8. Human Molecular Genetics vol. 24, (18) 5142-5153.

Notari M, Hu Y, Sutendra G, Dedei¿ Z, Lu M, Dupays L, Yavari A, Carr CA et al.(2015). iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death. Proceedings of the National Academy of Sciences of the United States of America vol. 112, (9) E973-E981.

Aziz Q, Li Y, Tinker A(2015). ATP-sensitive potassium channels and vascular function. Channels vol. 9, (1) 3-4.

Machhada A, Ang R, Ackland GL, Ninkina N, Buchman VL, Lythgoe MF, Trapp S, Tinker A et al.(2015). Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve. Heart Rhythm vol. 12, (11) 2285-2293.

Lane JD, Abramowitz J, Birnbaumer L, Tinker A(2014). 51Cardiac specific knockout of G-alpha-i2 in a murine model of heart failure. Europace vol. 16 Suppl 3,

Aziz Q, Thomas AM, Gomes J, Ang R, Sones WR, Li Y, Ng K-E, Gee L et al.(2014). The ATP-sensitive potassium channel subunit, Kir6.1, in vascular smooth muscle plays a major role in blood pressure control. Hypertension vol. 64, (3) 523-529.

Harmer SC, Mohal JS, Royal AA, McKenna WJ, Lambiase PD, Tinker A(2014). Cellular mechanisms underlying the increased disease severity seen for patients with long QT syndrome caused by compound mutations in KCNQ1. Biochem J vol. 462, (1) 133-142.

Youziel J, Akhbar AR, Aziz Q, Smith MEB, Caddick S, Tinker A, Baker JR(2014). Bromo- and thiomaleimides as a new class of thiol-mediated fluorescence 'turn-on' reagents. ORGANIC & BIOMOLECULAR CHEMISTRY vol. 12, (4) 557-560.

Arya VB, Aziz Q, Nessa A, Tinker A, Hussain K(2014). Congenital hyperinsulinism: clinical and molecular characterisation of compound heterozygous ABCC8 mutation responsive to Diazoxide therapy. Int J Pediatr Endocrinol vol. 2014, (1)

Tinker A, Aziz Q, Thomas A(2014). The role of ATP-sensitive potassium channels in cellular function and protection in the cardiovascular system. Br J Pharmacol vol. 171, (1) 12-23.

Posokhova E, Ng D, Opel A, Masuho I, Tinker A, Biesecker LG, Wickman K, Martemyanov KA(2013). Essential Role of the m(2)R-RGS6-I-KACh Pathway in Controlling Intrinsic Heart Rate Variability. PLOS ONE vol. 8, (10) Article ARTN e76973,

Sebastian S, Ang R, Abramowitz J, Weinstein LS, Chen M, Ludwig A, Birnbaumer L, Tinker A(2013). The in vivo regulation of heart rate in the murine sinoatrial node by stimulatory and inhibitory heterotrimeric G proteins. Am J Physiol Regul Integr Comp Physiol vol. 305, (4) R435-R442.

Ang R, Birnbaumer L, Gourine AV, Tinker A (2013). The role of GalphaO-mediated signalling in the central nervous mechanisms controlling sympathetic outflow to the heart. EUROPEAN HEART JOURNAL. vol. 34, 928-928.

Telezhkin V, Thomas AM, Harmer SC, Tinker A, Brown DA(2013). A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P-2. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY vol. 465, (7) 945-953.

Ang R, Birnbaumer L, Gourine A, Tinker A (2013). THE ROLE OF INHIBITORY G PROTEIN GALPHAO-MEDIATED SIGNALLING IN THE CENTRAL NERVOUS MECHANISMS CONTROLLING SYMPATHETIC OUTFLOW TO THE HEART. HEART. vol. 99, A121-A121.

Schwarzer S, Mashanov GI, Molloy JE, Tinker A(2013). Using total internal reflection fluorescence microscopy to observe ion channel trafficking and assembly. Methods Mol Biol vol. 998, 201-208.

Maden CH, Gomes J, Schwarz Q, Davidson K, Tinker A, Ruhrberg C(2012). NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. DEVELOPMENTAL BIOLOGY vol. 369, (2) 277-285.

Risebro CA, Petchey LK, Smart N, Gomes J, Clark J, Vieira JM, Yanni J, Dobrzynski H et al.(2012). Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3. Circ Res vol. 111, (2) e19-e31.

Harmer SC, Mohal JS, Kemp D, Tinker A(2012). Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel. Biochem J vol. 443, (3) 635-642.

Telezhkin V, Reilly JM, Thomas AM, Tinker A, Brown DA(2012). Structural Requirements of Membrane Phospholipids for M-type Potassium Channel Activation and Binding. JOURNAL OF BIOLOGICAL CHEMISTRY vol. 287, (13) 10001-10012.

Ang R, Sebastian S, Ludwig A, Birnbaumer L, Tinker A (2012). Mice with conditional knockout of Galphai2 in the cardiac pacemaker system exhibit tachycardia with loss of HF power on HRV analysis. CARDIOVASCULAR RESEARCH. vol. 93, S20-S20.

Aziz Q, Khambra T, Sones W, Thomas AM, Kotlikoff M, Tinker A (2012). Mouse model for the conditional deletion of the KATP channel subunit Kir6.1 in vascular smooth muscle. CARDIOVASCULAR RESEARCH. vol. 93, S74-S74.

Harmer SC, Mohal JS, Kemp D, Tinker A (2012). Rescue of long QT syndrome type 1 nonsense mutations by pharmacologically mediated readthrough. CARDIOVASCULAR RESEARCH. vol. 93, S105-S105.

Thomas AM, Aziz Q, Khambra T, Tinker A (2012). The KATP channel subunit, Kir6.2, is regulated by a Ca2+-dependent isoform of Protein Kinase C. CARDIOVASCULAR RESEARCH. vol. 93, S65-S65.

Nobles M, Sebastian S, Tinker A (2012). The role of RGS4 in the electrophysiology of atrial cardiac myocytes. CARDIOVASCULAR RESEARCH. vol. 93, S64-S64.

Aziz Q, Thomas AM, Khambra T, Tinker A(2012). Regulation of the ATP-sensitive potassium channel subunit, Kir6.2, by a Ca2+-dependent protein kinase C. J Biol Chem vol. 287, (9) 6196-6207.

Gomes J, Finlay M, Ahmed AK, Ciaccio EJ, Asimaki A, Saffitz JE, Quarta G, Nobles M et al.(2012). Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study. Eur Heart Journal vol. 33, (15) 1942-1953.

Ang R, Opel A, Tinker A(2012). The Role of Inhibitory G Proteins and Regulators of G Protein Signaling in the in vivo Control of Heart Rate and Predisposition to Cardiac Arrhythmias. Front Physiol vol. 3,

Thomas AM, Harmer SC, Khambra T, Tinker A(2011). Characterization of a binding site for anionic phospholipids on KCNQ1. Journal of Biological Chemistry vol. 286, 2088-2100.

Mashanov GI, Nobles M, Harmer SC, Molloy JE, Tinker A(2010). Direct observation of individual KCNQ1 potassium channels reveals their distinctive diffusive behavior. Journal of Biological Chemistry vol. 285, 3664-3675.

Campanella M, Casswell E, Chong S, Farah Z, Wieckowski MR, Abramov AR, TINKER A, Duchen MR(2008). Regulation of mitochondrial structure and function by IF1, the endogenous inhibitor of the mitochondrial ATPase. Cell Metabolism vol. 8, (1) 13-25.