Publications: Dr Matthew Caley
Quílez C, Bebiano LB, Jones E, Maver U, Meesters L, Parzymies P, Petiot E, Rikken G et al.
(
2024
)
.
Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
.
Journal of Investigative Dermatology
Tawfik S, Thomas B, Caley M, Jones E, O’Shaughnessy R, O’Toole E
(
2024
)
.
P038 Impact of cumulative low-level ozone on keratinocytes and implications for atopic eczema pathogenesis
.
British Journal of Dermatology
vol.
191
,
(
Supplement_1
)
i31
-
i32
.
Summan S, Mayes A, Gunn D, Madapura P, Gautrot J, Caley M, O’Toole E
(
2024
)
.
O08 Exploring the effect of skin ageing-related basement membrane collagen loss on nuclear mechanics
.
British Journal of Dermatology
vol.
190
,
(
6
)
e71
-
e72
.
Jones E, Garcha P, Aumailley M, O’Toole E, Rognoni E, Caley M
(
2024
)
.
O19 Improvement of a junctional epidermolysis bullosa mouse model
.
British Journal of Dermatology
vol.
190
,
(
6
)
e77
-
e77
.
Garcha P, Jones E, Ahmed AA, Aumailley M, Rognoni E, Caley M
(
2024
)
.
O20 Dissecting junctional epidermolysis bullosa heterogeneity
.
British Journal of Dermatology
vol.
190
,
(
6
)
e77
-
e78
.
Giusto E, Jones E, Enjalbert F, Ahmed A, Caley M, Rognoni E, O’Toole E
(
2024
)
.
P10 Janus kinase inhibitors to restore skin barrier function in a mouse model of Harlequin ichthyosis
.
British Journal of Dermatology
vol.
190
,
(
6
)
e83
-
e84
.
Khan MRA, Kirk T, Caley MP, Rognoni E
(
2024
)
.
P16 Fibroblast signalling crosstalk drives junctional epidermolysis bullosa disease progression
.
British Journal of Dermatology
vol.
190
,
(
6
)
e86
-
e86
.
Guri-Lamce I, Alrokh Y, Graham C, Maeshima R, Rognoni E, Caley M, Łaczmański Ł, Hart SL et al.
(
2024
)
.
Lipid Nanoparticles Efficiently Deliver the Base Editor ABE8e for COL7A1 Correction in Dystrophic Epidermolysis Bullosa Fibroblasts In Vitro
.
Journal of Investigative Dermatology
vol.
144
,
(
10
)
2314
-
2317.e3
.
Caley M, Idrissi M, Braiman L, Brener E, O'Toole E
(
2023
)
.
LB1754 Treatment of human palmoplantar keratoderma skin equivalents with a TRPV3 antagonist, KM-001
.
Journal of Investigative Dermatology
vol.
143
,
(
9
)
Giusto E, Enjalbert F, Rognoni E, Caley M, O’Toole E
(
2023
)
.
O13 JAK inhibitors to restore skin barrier function in ARCI
.
British Journal of Dermatology
vol.
189
,
(
1
)
e9
-
e10
.
Jones E, Marsh S, O'Shaughnessy R, Aumailley M, McGrath J, O’Toole E, Caley M
(
2023
)
.
O14 Junctional epidermolysis bullosa: repairing the epidermal lipid barrier
.
British Journal of Dermatology
vol.
189
,
(
1
)
e10
-
e10
.
Parzymies P, Jones EM, Mayes A, Messenger D, O’Toole E, Caley M
(
2023
)
.
O16 The novel roles of laminin α3 in epidermal barrier function and metabolism
.
British Journal of Dermatology
vol.
189
,
(
1
)
e11
-
e11
.
Summan SK, Mayes A, Gunn D, Gautrot J, Caley M, O’Toole E
(
2023
)
.
P16 How does skin ageing-related basement membrane collagen loss affect the nucleus?
.
British Journal of Dermatology
vol.
189
,
(
1
)
e20
-
e20
.
Garcha P, Jones E, Shelley J, Caley M
(
2023
)
.
P32 Restoring the ageing skin barrier in vitro
.
British Journal of Dermatology
vol.
189
,
(
1
)
e26
-
e27
.
Lohana P, Suryaprawira A, Woods EL, Dally J, Gait-Carr E, Alaidaroos NYA, Heard CM, Lee KY et al.
(
2023
)
.
Role of Enzymic Antioxidants in Mediating Oxidative Stress and Contrasting Wound Healing Capabilities in Oral Mucosal/Skin Fibroblasts and Tissues
.
Antioxidants
vol.
12
,
(
7
)
McGeoghan F, Camera E, Maiellaro M, Menon M, Huang M, Dewan P, Ziaj S, Caley MP et al.
(
2023
)
.
RNA sequencing and lipidomics uncovers novel pathomechanisms in recessive X-linked ichthyosis
.
Frontiers in Molecular Biosciences
vol.
10
,
Hindle S, Taggart E, Blowes L, Pennington D, Singh B, Caley M, Connelly J
(
2023
)
.
1035 Understanding dynamic immune responses within a 3D microfluidic model of human skin
.
Journal of Investigative Dermatology
vol.
143
,
(
5
)
Tawfik SS, Thomas B, Jones E, Caley M, O'Shaughnessy R, O'Toole E
(
2023
)
.
1157 Ozone as an aggravating factor in atopic eczema
.
Journal of Investigative Dermatology
vol.
143
,
(
5
)
Summan SK, Mayes A, Gunn DA, Gautrot J, Caley M, O'Toole E
(
2023
)
.
741 The effect of skin ageing-related basement membrane collagen loss on the nucleus
.
Journal of Investigative Dermatology
vol.
143
,
(
5
)
s127
-
s127
.
Jones E, Marsh S, Aumailley M, McGrath JA, O'Toole E, Rognoni E, Caley M
(
2023
)
.
753 Repairing the epidermal skin barrier in an in vivo model of junctional epidermolysis bullosa
.
Journal of Investigative Dermatology
vol.
143
,
(
5
)
Parzymies PJ, Jones E, Mayes A, Messenger D, O'Toole E, Caley M
(
2023
)
.
763 Novel roles of laminin α3 in epidermal homeostasis
.
Journal of Investigative Dermatology
vol.
143
,
(
5
)
Tawfik S, O'Toole E, Thomas B, Caley M, Jones E, O'Shaughnessy R
(
2023
)
.
ISID1157 - Ozone as an aggravating factor in atopic eczema
.
Frost JM, Amante SM, Okae H, Jones EM, Ashley B, Lewis RM, Cleal JK, Caley MP et al.
(
2023
)
.
Regulation of human trophoblast gene expression by endogenous retroviruses
.
Nature Structural & Molecular Biology
vol.
30
,
(
4
)
527
-
538
.
Smith CJ, Williams JL, Hall C, Casas J, Caley MP, O'Toole EA, Prasad R, Metherell LA
(
2023
)
.
Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation
.
Journal of Lipid Research
vol.
64
,
(
4
)
Parzymies PJ, Jones E, Mayes A, Messenger D, O'Toole E, Caley M
(
2023
)
.
Novel roles of laminin α3 in epidermal homeostasis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
S131
-
S131
.
Tawfik SS, Thomas B, Jones E, Caley M, O'Shaughnessy R, O'Toole E
(
2023
)
.
Ozone as an aggravating factor in atopic eczema
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
S198
-
S198
.
Jones E, Marsh S, Aumailley M, McGrath JA, O'Toole E, Rognoni E, Caley M
(
2023
)
.
Repairing the epidermal skin barrier in an in vivo model of junctional epidermolysis bullosa
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
S129
-
S129
.
Summan SK, Mayes A, Gunn DA, Gautrot J, Caley M, O'Toole E
(
2023
)
.
The effect of skin ageing-related basement membrane collagen loss on the nucleus
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
S127
-
S127
.
Caley M, Idrissi M, Braiman L, Brener E, O'Toole E
(
2023
)
.
Treatment of human palmoplantar keratoderma skin equivalents with a TRPV3 antagonist, KM-001
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
B26
-
B26
.
Hindle S, Taggart E, Blowes L, Pennington D, Singh B, Caley M, Connelly J
(
2023
)
.
Understanding dynamic immune responses within a 3D microfluidic model of human skin
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
143
,
S177
-
S177
.
Tawfik SS, Thomas B, Jones E, Caley MP, O’Shaughnessy R, O’Toole EA
(
2022
)
.
144 Carbonylated proteins and Ozone in atopic eczema
.
Journal of Investigative Dermatology
vol.
142
,
(
12
)
Smith CJ, Williams JL, Hall C, Caley MP, O’Toole EA, Prasad R, Metherell LA
(
2022
)
.
181 Sphingosine 1-phosphate lyase insufficiency induced ichthyosis is due to sphingolipid imbalance, increased differentiation, and aberrant intercellular junctions
.
Journal of Investigative Dermatology
vol.
142
,
(
12
)
Parzymies P, Jones E, Caley MP, O’Toole EA, Messenger D, Mayes A
(
2022
)
.
184 The role of the Laminin 332 in cholesterol transport in dry and Aged skin
.
Journal of Investigative Dermatology
vol.
142
,
(
12
)
Jones E, Marsh S, O’Shaughnessy R, Aumailley M, McGrath JA, O’Toole EA, Caley MP
(
2022
)
.
191 Junctional Epidermolysis Bullosa:Repairing The Epidermal Skin Barrier
.
Journal of Investigative Dermatology
vol.
142
,
(
12
)
Dina DO, Caley MP, Raj N, O’Toole EA, Connelly J
(
2022
)
.
216 Understanding the Mechanisms of Epidermal Barrier Damage and Repair Using 3D Skin Equivalent Models
.
Journal of Investigative Dermatology
vol.
142
,
(
12
)
Tawfik S, Thomas B, Jones E, Caley M, O'Shaughnessy R, O'Toole E, Thomas B, Prasad Baruah K
(
2022
)
.
ESDR144 - Carbonylated proteins and Ozone in atopic eczema
.
Dina D, Caley M, Raj N, O'Toole E, Connelly J
(
2022
)
.
ESDR216 - Understanding the Mechanisms of Epidermal Barrier Damage and Repair Using 3D Skin Equivalent Models
.
Parzymies P, Jones E, Caley M, O'Toole E, Messenger D, Mayes A
(
2022
)
.
ESDR184 - The role of the Laminin 332 in cholesterol transport in dry and Aged skin
.
Smith C, Williams J, Hall C, Caley M, O'Toole E, Prasad R, Metherell L
(
2022
)
.
ESDR181 - Sphingosine 1-phosphate lyase insufficiency induced ichthyosis is due to sphingolipid imbalance, increased differentiation, and aberrant intercellular junctions
.
Jones E, Marsh S, O'Shaughnessy R, Aumailley M, McGrath J, O'Toole E, Caley M
(
2022
)
.
ESDR191 - Junctional Epidermolysis Bullosa:Repairing The Epidermal Skin Barrier
.
Smith CJ, Parkinson EK, Yang J, Pratten J, O'Toole EA, Caley MP, Braun KM
(
2022
)
.
Investigating wound healing characteristics of gingival and skin keratinocytes in organotypic cultures
.
Journal of Dentistry
vol.
125
,
Tawfik SS, Thomas B, Jones E, Caley MP, O'Shaughnessy R, O'Toole EA
(
2022
)
.
Carbonylated proteins and Ozone in atopic eczema
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
142
,
S204
-
S204
.
Huang M, Miettinen S, Caley M, O'Toole E
(
2022
)
.
Finding a new treatment for X-linked recessive ichthyosis
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
187
,
E12
-
E12
.
Jones E, O'Toole E, Caley M
(
2022
)
.
Investigating the role of the basement membrane in modulating the inflammasome in ageing skin
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
186
,
E235
-
E235
.
Jones E, Stewart-McGuiness C, O'Toole E, Caley M
(
2022
)
.
Investigating the role of the basement membrane in modulating the skin inflammasome
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
187
,
E17
-
E18
.
Jones E, Marsh S, O'Shaughnessy R, Aumailley M, McGrath JA, O'Toole EA, Caley MP
(
2022
)
.
Junctional Epidermolysis Bullosa:Repairing The Epidermal Skin Barrier
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
142
,
S213
-
S213
.
Smith CJ, Williams JL, Hall C, Caley MP, O'Toole EA, Prasad R, Metherell LA
(
2022
)
.
Sphingosine 1-phosphate lyase insufficiency induced ichthyosis is due to sphingolipid imbalance, increased differentiation, and aberrant intercellular junctions
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
142
,
S211
-
S211
.
Parzymies P, Jones E, Caley MP, O'Toole EA, Messenger D, Mayes A
(
2022
)
.
The role of the Laminin 332 in cholesterol transport in dry and Aged skin
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
142
,
S212
-
S212
.
Parzymies P, Jones E, Caley M, O'Toole E, Mayes A, Messenger D
(
2022
)
.
The role of the laminin 332-actin-cholesterol axis in skin conditions with altered lipid profiles
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
186
,
E228
-
E228
.
Dina DO, Caley MP, Raj N, O'Toole EA, Connelly J
(
2022
)
.
Understanding the Mechanisms of Epidermal Barrier Damage and Repair Using 3D Skin Equivalent Models
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
142
,
S217
-
S217
.
Smith CJ, Williams JL, Caley MP, O’Toole EA, Prasad R, Metherell LA
(
2021
)
.
099 Ichthyosis associated with sphingosine 1-phosphate lyase deficiency is due to aberrant calcium and sphingolipid regulation
.
Journal of Investigative Dermatology
vol.
141
,
(
10
)
s165
-
s165
.
Caley MP, Martins VL, Moore K, Lashari M, Nissinen L, Kähäri V-M, Alexander S, Jones E et al.
(
2021
)
.
Loss of the laminin subunit alpha-3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma
.
Br J Dermatol
vol.
184
,
(
5
)
923
-
934
.
Smith CJ, Williams JL, Caley MP, O'Toole EA, Prasad R, Metherell LA
(
2021
)
.
Ichthyosis associated with sphingosine 1-phosphate lyase deficiency is due to aberrant calcium and sphingolipid regulation
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
141
,
S165
-
S165
.
Langton AK, Ayer J, Griffiths TW, Rashdan E, Naidoo K, Caley MP, Birch‐Machin MA, O'Toole EA et al.
(
2020
)
.
Distinctive clinical and histological characteristics of atrophic and hypertrophic facial photoageing
.
Journal of the European Academy of Dermatology and Venereology
vol.
35
,
(
3
)
762
-
768
.
Enjalbert F, Dewan P, Caley MP, Jones EM, Morse MA, Kelsell DP, Enright AJ, O'Toole EA
(
2020
)
.
3D model of harlequin ichthyosis reveals inflammatory therapeutic targets
.
Journal of Clinical Investigation
Caley M, Mai Jones E
(
2019
)
.
Junctional Epidermolysis Bullosa: Bottom Up Control Of The Skin Barrier?
.
Jones EM, Marsh S, O’Shaughnessy RF, CAMERA E, Picardo M, Aumailley M, O’Toole E, Caley M
(
2019
)
.
274 Junctional Epidermolysis Bullosa: Bottom Up Control Of The Skin Barrier?
.
Journal of Investigative Dermatology
.
vol.
139
,
Caley M, Marsh S, Martins VL, Corbett-Jones T, Chen M, Di W, Sheer D, McGrath JA et al.
(
2019
)
.
298 Defective DNA Repair and Chromosomal Instability in RDEB
.
Journal of Investigative Dermatology
.
vol.
139
,
Hassan S, Purdie KJ, Wang J, Harwood CA, Proby CM, Pourreyron C, Mladkova N, Nagano A et al.
(
2019
)
.
A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing
.
International Journal of Molecular Sciences
vol.
20
,
(
14
)
Langton AK, Ayer J, Griffiths TW, Rashdan E, Naidoo K, Caley MP, Birch-Machin MA, O'Toole E et al.
(
2019
)
.
Differential ageing responses to chronic ultraviolet irradiation: characterizing the molecular phenotype of atrophic and hypertrophic facial skin
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
180
,
E198
-
E198
.
Jones EM, Marsh ST, O'Shaughnessy RF, Aumailley M, Camera E, Picardo M, McGrath JA, O'Toole EA et al.
(
2019
)
.
Laminin 332: bottom-up control of the skin barrier?
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
180
,
E185
-
E185
.
Thomas BR, Caley MP, O'Toole EA
(
2019
)
.
Novel frameshift variant in <i>EBP</i>: late diagnosis of Conradi-Hunermann syndrome in a 41-year-old woman
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
181
,
79
-
80
.
Marsh S, Caley MP, Martins VLC, Corbett-Jones T, Chen M, Di W, Sheer D, McGrath JA et al.
(
2019
)
.
Type VII collagen and Nesprin 2: LINCing the basement membrane to altered cell cycle and increased DNA damage
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
180
,
E188
-
E189
.
Enjalbert F, Dewan P, Caley M, Morse M, Kelsell D, O'Toole E
(
2019
)
.
Understanding the role of ABCA12 in the pathogenesis of harlequin ichthyosis
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
180
,
E185
-
E185
.
Enjalbert F, Dewan P, Caley MP, Fell B, Morse M, Kelsell D, Enright A, O'Toole EA
(
2018
)
.
661 Understanding the role of ABCA12 in the pathogenesis of harlequin ichthyosis
.
Journal of Investigative Dermatology
.
vol.
138
,
Jones E, Marsh S, O'Shaughnessy R, Aumailley M, O'Toole EA, Caley MP
(
2018
)
.
680 A role for the basement membrane in skin lipid trafficking
.
Journal of Investigative Dermatology
.
vol.
138
,
Marsh S, Caley MP, Martins V, Chen M, McGrath J, Barnes M, O'Toole EA
(
2018
)
.
812 Type VII collagen and Nesprin 2, LINCing the basement membrane to altered cell cycle and increased DNA damage
.
Journal of Investigative Dermatology
.
vol.
138
,
Caley M, Wall IB, Peake M, Kipling D, Giles P, Thomas DW, Stephens P
(
2018
)
.
Development and Characterisation of a Human Chronic Skin Wound Cell Line—Towards an Alternative for Animal Experimentation
.
International Journal of Molecular Sciences
vol.
19
,
(
4
)
Jones E, Marsh S, O'Shaughnessy R, Aumailley M, O'Toole EA, Caley MP
(
2018
)
.
A role for the basement membrane in skin lipid trafficking
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
138
,
S116
-
S116
.
Milligan D, Newman J, Caley M, Wainwright L, Jenkins G, Philpott M, Bishop C
(
2018
)
.
Development of a three-dimensional living skin equivalent to explore the influence of senescence on the skin ageing phenotype
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E420
-
E420
.
Smith CJ, Caley M, Parkinson EK, O'Toole EA, Pratten J, Yang J
(
2018
)
.
INVESTIGATING THE DIFFERENCES IN THE WOUND HEALING RESPONSES OF SKIN AND GINGIVAL KERATINOCYTES
.
WOUND REPAIR AND REGENERATION
.
vol.
26
,
A30
-
A31
.
Smith CJ, Caley M, Parkinson EK, O'Toole EA, Pratten J, Yang J, Braun KM
(
2018
)
.
Investigating the differences in the wound healing responses of skin and gingival keratinocytes
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E416
-
E416
.
Enjalbert F, Dewan P, Caley M, Fell B, Morse M, Kelsell D, Enright A, O'Toole E
(
2018
)
.
Investigating the role of <i>ABCA12</i> in the pathomechanisms of harlequin ichthyosis
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E406
-
E406
.
Caley M, Martins V, Moore K, Lashari M, Marshall J, O'Toole E
(
2018
)
.
Loss of Lamα3 drives M2 macrophage differentiation in squamous cell carcinoma
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E399
-
E400
.
Huang M, Ruban E, Caley M, O'Toole E
(
2018
)
.
Phospholipase C-β4 regulation of chromatin via kindlin-2 in cutaneous squamous cell carcinoma
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E409
-
E409
.
Jones E, Marsh S, O'Shaugnessy R, Aumailley M, O'Toole E, Caley M
(
2018
)
.
The role of laminin 332 in skin lipid biosynthesis
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E407
-
E408
.
Marsh S, Caley MP, Martins V, Chen M, McGrath J, Barnes M, O'Toole EA
(
2018
)
.
Type VII collagen and Nesprin 2, LINCing the basement membrane to altered cell cycle and increased DNA damage
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
138
,
S138
-
S138
.
Alexander SC, Marsh S, Caley M, O'Toole EA
(
2018
)
.
Understanding Angiogenesis in Squamous Cell Carcinoma with Loss of Type VII Collagen
.
JOURNAL OF PATHOLOGY
.
vol.
246
,
S44
-
S44
.
Enjalbert F, Dewan P, Caley MP, Fell B, Morse M, Kelsell D, Enright A, O'Toole EA
(
2018
)
.
Understanding the role of ABCA12 in the pathogenesis of harlequin ichthyosis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
138
,
S112
-
S112
.
Caley M, Martins V, Moore K, Lashari M, Marshall J, O’Toole EA
(
2017
)
.
336 Tumour associated macrophage recruitment in SCC
.
Journal of Investigative Dermatology
.
vol.
137
,
Shams F, Krupiczojc MA, Alexander S, Rashidghamat E, McGrath J, Caley M, O’Toole EA, Harwood CA
(
2017
)
.
568 Investigation of the role of type VII collagen in the HIF1α induced pro-angiogenic pathway
.
Journal of Investigative Dermatology
.
vol.
137
,
Milligan D, Newman J, Caley M, Wainwright L, Jenkins G, Philpott M, Bishop C
(
2017
)
.
682 Development of a 3D living skin equivalent to explore the influence of senescence on the skin ageing phenotype
.
Journal of Investigative Dermatology
.
vol.
137
,
Marsh S, Caley M, Martins V, Barnes MR, Chen M, O'Toole EA
(
2017
)
.
Loss of keratinocyte type VII collagen induces increased DNA damage in vitro and in vivo
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
Conference:
ESDR 2017
vol.
137
,
S225
-
S225
.
Enjalbert F, Dewan P, Caley M, Fell B, Morse M, Kelsell DP, Enright A, O'Toole EA
(
2017
)
.
Understanding the role of ABCA12 in the Pathogenesis of Harlequin Ichthyosis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
Conference:
ESDR 2017
vol.
137
,
S208
-
S208
.
McGeoghan F, Menon M, Dewan P, Caley M, Donaldson M, O’Toole EA
(
2016
)
.
132 Identification of novel pathways linked to the pathogenesis of Recessive X-Linked Ichthyosis
.
Journal of Investigative Dermatology
.
vol.
136
,
Enjalbert F, Dewan P, Caley M, Fell B, Donaldson M, Kelsell DP, O’Toole EA
(
2016
)
.
133 Understanding the role of ABCA12 in the pathogenesis of Harlequin Ichthyosis
.
Journal of Investigative Dermatology
.
vol.
136
,
Caley M, Martins V, Moore K, Lashari M, Kähäri V, Nissinen L, Donaldson M, Marshall J et al.
(
2016
)
.
472 Loss of Laminin α3 drives SCC invasion via ROCK signalling
.
Journal of Investigative Dermatology
.
vol.
136
,
Krupiczojc MA, Caley M, Marsh S, Donaldson M, Martins V, O’Toole E
(
2016
)
.
569 Loss of collagen 7 drives HIF-1 alpha induced pro-angiogenic pathways
.
Journal of Investigative Dermatology
.
vol.
136
,
McGeoghan FT, O’Toole E, Caley M, Menon M, Dewan P, Donaldson M
(
2016
)
.
375 Modelling and understanding pathomechanisms of X-linked recessive ichthyosis in vitro
.
Journal of Investigative Dermatology
.
vol.
136
,
Branco MR, King M, Perez-Garcia V, Bogutz AB, Caley M, Fineberg E, Lefebvre L, Cook SJ et al.
(
2016
)
.
Maternal DNA Methylation Regulates Early Trophoblast Development
.
Developmental Cell
vol.
36
,
(
2
)
152
-
163
.
O'Toole EA, Ruban EL, Balogun M, Martins VL, Caley MP, Falasca M
(
2016
)
.
Phospholipase C beta4 is a therapeutic target in cutaneous squamous cell carcinoma
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
175
,
56
-
57
.
Caley M, Martins V, Moore K, Lashari M, Donaldson M, Marshall JF, O'Toole EA
(
2016
)
.
ROCK and Rac1 signalling in squamous cell carcinoma with loss of laminin 332
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
174
,
E51
-
E51
.
Caley MP, King H, Shah N, Wang K, Rodriguez-Teja M, Gronau JH, Waxman J, Sturge J
(
2015
)
.
Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces
.
Clinical & Experimental Metastasis
vol.
33
,
(
2
)
151
-
165
.
Hill DS, Robinson NDP, Caley MP, Chen M, O'Toole EA, Armstrong JL, Przyborski S, Lovat PE
(
2015
)
.
A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion
.
Molecular Cancer Therapeutics
vol.
14
,
(
11
)
2665
-
2673
.
Kopecki Z, Yang GN, Jackson JE, Melville EL, Calley MP, Murrell DF, Darby IA, O'Toole EA et al.
(
2015
)
.
Cytoskeletal protein Flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression
.
Oncotarget
vol.
6
,
(
34
)
36426
-
36440
.
Martins VL, Caley MP, Moore K, Szentpetery Z, Marsh ST, Murrell DF, Kim MH, Avari M et al.
(
2015
)
.
Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC
.
J Natl Cancer Inst
vol.
108
,
(
1
)
Pinato DJ, Trousil S, Caley M, Mauri FA, Aboagye E, Sharma R
(
2015
)
.
Pharmacological inhibition of Axl tyrosine kinase as a novel therapeutic strategy in hepatocellular carcinoma
.
Journal of Clinical Oncology
.
vol.
33
,
e15152
-
e15152
.
Caley MP, Martins VLC, O'Toole EA
(
2015
)
.
Metalloproteinases and Wound Healing
.
Advances in Wound Care
vol.
4
,
(
4
)
225
-
234
.
McGeoghan F, Dewan P, Caley M, Donaldson M, O'Toole E
(
2015
)
.
Generation of an <i>in vitro</i> three-dimensional model of X-linked recessive ichthyosis
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
172
,
E40
-
E40
.
Marsh S, Martins V, Caley M, Barnes M, Donaldson MJ, O'toole E
(
2015
)
.
Loss of keratinocyte type VII collagen induces pro-carcinogenic transcriptomic pathways
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
135
,
S44
-
S44
.
McGeoghan FT, Derwin P, Caley M, Donaldson MJ, O'toole E
(
2015
)
.
Modelling X-linked recessive ichthyosis <i>in vitro</i>
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
135
,
S62
-
S62
.
Martins V, Caley M, Moore K, Szentpetery Z, Marsh S, Murrell DF, Kaehaeri V, McGrath J et al.
(
2015
)
.
Skin type VII collagen acts as a tumour suppressor by regulating TGFβ and angiogenesis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
135
,
S28
-
S28
.
Caley M, Martins V, Marsh S, Moore K, Lashari M, Donaldson MJ, Marshall J, O'toole E
(
2015
)
.
Squamous Cell Carcinoma progression and Laminin 332
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
135
,
S23
-
S23
.
Rodriguez‐Teja M, Gronau JH, Breit C, Zhang YZ, Minamidate A, Caley MP, McCarthy A, Cox TR et al.
(
2014
)
.
AGE‐modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival
.
The Journal of Pathology
vol.
235
,
(
4
)
581
-
592
.
Cichoń MA, Szentpetery Z, Caley MP, Papadakis ES, Mackenzie IC, Brennan CH, O'Toole EA
(
2014
)
.
The receptor tyrosine kinase Axl regulates cell-cell adhesion and stemness in cutaneous squamous cell carcinoma
.
Oncogene
vol.
33
,
(
32
)
4185
-
4192
.
Kopecki Z, Yang G, Jackson J, Melville E, Martin V, Caley M, Proby C, Pouniotis D et al.
(
2014
)
.
Cytoskeletal protein Flii is elevated in human cSCCs and overexpression of Flii in mice leads to higher incidence and severity of tumour formation
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
134
,
S28
-
S28
.
Caley M, Martins V, Moore K, Marshall J, O'toole E
(
2014
)
.
Diverse roles for laminin 332 subunits in squamous cell carcinoma
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
134
,
S19
-
S19
.
Caley M, Martins V, Moore K, Marshall J, O'Toole E
(
2014
)
.
Diverse roles for laminin-332 subunits in squamous cell carcinoma
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
170
,
E26
-
E26
.
Marsh S, Martins V, Caley M, Barnes M, Donaldson M, O'Toole E
(
2014
)
.
Global transcriptomic changes in primary keratinocytes with loss of basement membrane genes
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
170
,
E37
-
E38
.
Peake MA, Caley M, Giles PJ, Wall I, Enoch S, Davies LC, Kipling D, Thomas DW et al.
(
2014
)
.
Identification of a transcriptional signature for the wound healing continuum
.
Wound Repair Regen
vol.
22
,
(
3
)
399
-
405
.
Ruban EL, Balogun MA, Martins V, Caley M, Raimondi C, O'toole E, Falasca M
(
2014
)
.
Phospholipase C beta4 regulates invasion and proliferation in cutaneous SCC <i>in vivo</i>
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
134
,
S22
-
S22
.
Marsh S, Martins V, Caley M, Barnes M, Donaldson M, O'toole E
(
2014
)
.
RNA-Seqing the skin basement membrane
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
134
,
S25
-
S25
.
Pellegrino L, Stebbing J, Braga VM, Frampton AE, Jacob J, Buluwela L, Jiao LR, Periyasamy M et al.
(
2013
)
.
miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts
.
Nucleic Acids Res
vol.
41
,
(
10
)
5400
-
5412
.
Martins VL, Caley M, O'Toole EA
(
2013
)
.
Matrix metalloproteinases and epidermal wound repair
.
Cell Tissue Res
vol.
351
,
(
2
)
255
-
268
.
Palmieri C, Caley MP, Purshouse K, Fonseca A-V, Rodriguez-Teja M, Kogianni G, Woodley L, Odendaal J et al.
(
2013
)
.
Endo180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer
.
Br J Cancer
vol.
108
,
(
1
)
163
-
169
.
Stephens P, Caley M, Peake M
(
2013
)
.
Alternatives for animal wound model systems
.
Methods in Molecular Biology
vol.
1037
,
177
-
201
.
Stephens P, Caley M, Peake M
(
2013
)
.
Alternatives for animal wound model systems
.
Methods Mol Biol
vol.
1037
,
177
-
201
.
Caley MP, Martins V, Moore K, Marshall JF, O'Toole EA
(
2013
)
.
Diverse roles for laminin 332 subunits in squamous cell carcinoma
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
133
,
S64
-
S64
.
Ali I, Gautrot J, Caley M, Marshall JF, Wheeler A
(
2013
)
.
Formation and inhibition of invadopodia in oral squamous cell carcinoma
.
MOLECULAR BIOLOGY OF THE CELL
.
vol.
24
,
Martins VL, Caley MP, Moore K, Szentpetery Z, Murrell DF, Kim MH, McGrath JA, Cerio R et al.
(
2013
)
.
Loss of type VII collagen in cutaneous SCC increases angiogenesis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
133
,
S158
-
S158
.
Ruban EL, Martins VL, Caley M, Raimondi C, Falasca M, O'Toole EA
(
2013
)
.
Phospholipase C-beta 4 regulates proliferation and invasion in cutaneous SCC
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
133
,
S73
-
S73
.
Marsh ST, Caley MP, Kwan A, O'Toole EA, Donaldson M
(
2013
)
.
Transcriptome profiling identifies novel functions of acitretin in human epidermis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
133
,
S186
-
S186
.
Sturge J, Caley M, Purshouse K, Fonseca A-V, Rodriguez-Teja M, Kogianni G, Waxman J, Palmieri C
(
2012
)
.
Abstract P2-02-03: The Collagen Receptor Endo180: A Metastatic Plasma Marker In Breast Cancer Modulated By Bisphosphonate Treatment
.
Cancer Research
.
vol.
72
,
Ramasamy K, Khatun H, Macpherson L, Caley MP, Sturge J, Mufti GJ, Schey SA, Calle Y
(
2012
)
.
Fluorescence-based experimental model to evaluate the concomitant effect of drugs on the tumour microenvironment and cancer cells
.
Br J Haematol
vol.
157
,
(
5
)
564
-
579
.
Caley MP, Kogianni G, Adamarek A, Gronau JH, Rodriguez-Teja M, Fonseca A-V, Mauri F, Sandison A et al.
(
2012
)
.
TGFβ1-Endo180-dependent collagen deposition is dysregulated at the tumour-stromal interface in bone metastasis
.
J Pathol
vol.
226
,
(
5
)
775
-
783
.
Singh M, Caley M, Jones M, Breuer J, O'Toole E
(
2012
)
.
Keratin 15 and VZV replication in skin
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
132
,
S112
-
S112
.
Martins V, Caley M, Moore K, Murrell DF, McGrath JA, Chen M, Marshall JF, O'Toole EA
(
2012
)
.
Loss of keratinocyte type VII collagen in SCC increases TGF-beta signalling and angiogenesis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
132
,
S45
-
S45
.
Martins V, Caley M, Moore K, Chen M, Marshall J, O'Toole E
(
2012
)
.
Loss of type VII collagen in squamous cell carcinoma increases angiogenesis <i>in vitro</i> and <i>in vivo</i>
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
166
,
e25
-
e26
.
Szentpetery Z, Cichon M, Caley M, O'Toole E
(
2012
)
.
The receptor tyrosine kinase Axl regulates intercellular adhesion, epithelial-mesenchymal transition and stemness in cutaneous squamous cell carcinoma
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
132
,
S45
-
S45
.
Sturge J, Caley MP, Waxman J
(
2011
)
.
Bone metastasis in prostate cancer: emerging therapeutic strategies
.
Nat Rev Clin Oncol
vol.
8
,
(
6
)
357
-
368
.
Sturge J, Caley MP, Waxmanin J
(
2011
)
.
Authors' reply: Expanding horizons in metastatic prostate cancer treatment
.
NATURE REVIEWS CLINICAL ONCOLOGY
vol.
8
,
(
10
)
Sturge J, Caley MP, Waxman J
(
2011
)
.
Bone metastasis in prostate cancer: emerging therapeutic strategies (vol 8, pg 357, 2011)
.
NATURE REVIEWS CLINICAL ONCOLOGY
vol.
8
,
(
10
)
568
-
568
.
Bruche S, Caley MP, Pshezhetskiy D, Sturge J
(
2010
)
.
Sphingosine kinase-1 and the collagen-binding receptor Endo180 cooperate to mediate collagen remodelling by stromal fibroblasts
.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
.
vol.
91
,
A9
-
A9
.
Mantripragada KK, Caley M, Stephens P, Jones CJ, Kluwe L, Guha A, Mautner V, Upadhyaya M
(
2008
)
.
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals
.
Genes Chromosomes Cancer
vol.
47
,
(
3
)
238
-
246
.
Mantripragada KK, Caley M, Stephens P, Jones CJ, Kluwe L, Guha A, Mautner V, Upadhyaya M
(
2008
)
.
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type I individuals
.
GENES CHROMOSOMES & CANCER
vol.
47
,
(
3
)
238
-
246
.
Caley M, Wall I, Kipling D, Thomas DW, Stephens P
(
2007
)
.
Development and characterisation of a human cell-based chronic wound bioassay
.
WOUND REPAIR AND REGENERATION
vol.
15
,
(
6
)
A133
-
A133
.