Publications: Dr Simon McArthur
Sheikh MH, Henson S, Loiola RA, Mercurio S, Colamatteo A, Maniscalco GT, De Rosa V, Mcarthur S et al.(2020).
Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier. Journal of Neuroinflammation
McArthur S, Juban G, Gobbetti T, Desgeorges T, Theret M, Gondin J, Toller-Kawahisa JE, Reutelingsperger CP et al.(2020).
Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation. Journal of Clinical Investigation
vol. 130,
(3)
1156-1167.
Wickstead ES, Karim HA, Manuel RE, Biggs CS, Getting SJ, McArthur S(2020).
Reversal of β-Amyloid-Induced Microglial Toxicity In Vitro by Activation of Fpr2/3. Oxid Med Cell Longev
vol. 2020,
Lopez Tremoleda J, Wall J, Naganathar V, Praditsuktavorn B, Bugg O, Mcarthur S, Thiemermann C, Brohi K(2019).
Modelling cardiac dysfunction following traumatic haemorrhage injury: impact on myocardial integrity. Frontiers in Immunology
vol. 10,
Wan H, Li X, Ahmad U, Huang Y, Uttagomol J, Rehman A, Zhou K, Warnes G et al.(2019).
Desmoglein-3 acts as a pro-survival protein by suppressing reactive oxygen species and doming whilst augmenting the tight junctions in MDCK cells. Mechanisms of Ageing and Development
Loiola RA, Wickstead ES, Solito E, Mcarthur S(2019).
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Frontiers in Endocrinology
Loiola RA, Wickstead ES, Solito E, McArthur S(2019).
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Front Endocrinol (Lausanne)
vol. 10,
Barrios-Silva LV, Parnell M, Shinwari ZB, Chaudhary GA, Xenofontos T, van Bekhoven A, MCARTHUR S, Elliott BT(2018).
Activin sub-family peptides predict chronological age in humans. Physiological Reports
vol. 6,
(17)
e13823-e13823.
Hoyles L, Snelling T, Umlai U-K, Nicholson JK, Carding SR, Glen RC, MCARTHUR S(2018).
Microbiome-host systems interactions: Protective effects of propionate upon the bloodbrain barrier. BMC Microbiome
vol. 6,
55-55.
Bruzzi S, Sutti S, Toscani A, Bozzola C, Reutelingsperger C, Kusters D, Mcarthur S, Perretti M et al. (2017).
Annexin A1 supplementation prevents the progression to fibrosis of nonalcoholic steatoepatitis (NASH). JOURNAL OF HEPATOLOGY.
Conference: The International Liver Congress 2017
vol. 66,
S608-S608.
Virdee K, Kentrop J, Jupp B, Venus B, Hensman D, McArthur S, Wilkinson J, Robbins TW et al.(2016).
Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory. Psychopharmacology (Berl)
vol. 233,
(21-22)
3751-3761.
McArthur S, Loiola RA, Maggioli, E, Errede M, Virgintino D, SOLITO E(2016).
The restorative role of annexin A1 at the blood–brain barrier. Fluids and Barriers of the CNS
vol. 13,
(17)
McArthur S, Pienaar IS, Siddiqi SM, Gillies GE(2016).
Sex-specific disruption of murine midbrain astrocytic and dopaminergic developmental trajectories following antenatal GC treatment. Brain Struct Funct
vol. 221,
(5)
2459-2475.
Maggioli E, McArthur S, Mauro C, Kieswich J, Kusters DHM, Reutelingsperger CPM, Yaqoob M, Solito E(2016).
Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking. Brain, Behavior, and Immunity
vol. 51,
212-222.
Shende VH, McArthur S, Gillies GE, Opacka-Juffry J(2015).
Astroglial Plasticity Is Implicated in Hippocampal Remodelling in Adult Rats Exposed to Antenatal Dexamethasone. Neural Plast
vol. 2015,
McArthur S, Gobbetti T, Kusters DHM, Reutelingsperger CP, Flower RJ, Perretti M(2015).
Definition of a novel pathway centered on lysophosphatidic acid to recruit monocytes during the resolution phase of tissue inflammation. Journal of Immunology
vol. 195,
(3)
1139-1151.
Gobbetti T, Coldewey SM, Chen J, McArthur S, Le Faouder P, Cenac N, Flower RJ, Thiemermann C et al.(2014).
Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proceedings of the National Academy of Sciences of the United States of America
vol. 111,
(52)
18685-18690.
Gillies GE, Virdee K, McArthur S, Dalley JW(2014).
Sex-dependent diversity in ventral tegmental dopaminergic neurons and developmental programing: A molecular, cellular and behavioral analysis. Neuroscience
vol. 282,
69-85.
Virdee K, McArthur S, Brischoux F, Caprioli D, Ungless MA, Robbins TW, Dalley JW, Gillies GE(2014).
Antenatal glucocorticoid treatment induces adaptations in adult midbrain dopamine neurons, which underpin sexually dimorphic behavioral resilience. Neuropsychopharmacology
vol. 39,
(2)
339-350.
Locatelli I, Sutti S, Jindal A, Vacchiano M, Bozzola C, Reutelingsperger C, Kusters D, Bena S et al.(2014).
Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice. Hepatology
vol. 60,
(2)
531-544.
Thompson D, McArthur S, Hislop JN, Flower RJ, Perretti M(2014).
Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: Association with cell protection from apoptosis. Journal of Biological Chemistry
vol. 289,
(52)
36166-36178.
Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ, Perretti M(2013).
Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A
vol. 110,
(45)
18232-18237.
Cash JL, Bena S, Headland SE, McArthur S, Brancaleone V, Perretti M(2013).
Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep
vol. 14,
(11)
999-1007.
Nadkarni S, McArthur S(2013).
Oestrogen and immunomodulation: new mechanisms that impact on peripheral and central immunity. Curr Opin Pharmacol
vol. 13,
(4)
576-581.
Katsouri L, Vizcaychipi MP, McArthur S, Harrison I, Suárez-Calvet M, Lleo A, Lloyd DG, Ma D et al.(2013).
Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease. Neurobiol Aging
vol. 34,
(4)
1105-1115.
Cristante E, McArthur S, Mauro C, Maggioli E, Romero IA, Wylezinska-Arridge M, Couraud PO, Lopez-Tremoleda J et al.(2013).
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proc Natl Acad Sci U S A
vol. 110,
(3)
832-841.
Dalli J, Montero-Melendez T, McArthur S, Perretti M(2012).
Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol
vol. 3,
McArthur S, Robinson IC, Gillies GE(2011).
Novel ontogenetic patterns of sexual differentiation in arcuate nucleus GHRH neurons revealed in GHRH-enhanced green fluorescent protein transgenic mice. Endocrinology
vol. 152,
(2)
607-617.
McArthur S, Gillies GE(2011).
Peripheral vs. Central Sex Steroid Hormones in Experimental Parkinson's Disease. Front Endocrinol (Lausanne)
vol. 2,
McArthur S, Cristante E, Paterno M, Christian H, Roncaroli F, Gillies GE, Solito E(2010).
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. J Immunol
vol. 185,
(10)
6317-6328.
Gillies GE, McArthur S(2010).
Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines. Pharmacol Rev
vol. 62,
(2)
155-198.
Yazid S, Ayoub SS, Solito E, McArthur S, Vo P, Dufton N, Flower RJ(2010).
Anti-allergic drugs and the Annexin-A1 system. Pharmacol Rep
vol. 62,
(3)
511-517.
Gillies GE, McArthur S(2010).
Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson's disease: A contribution to sex-specific neuroprotection by estrogens. Horm Behav
vol. 57,
(1)
23-34.
McArthur S, Yazid S, Christian H, Sirha R, Flower R, Buckingham J, Solito E(2009).
Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization. FASEB J
vol. 23,
(11)
4000-4010.
Yazid S, Solito E, Christian H, McArthur S, Goulding N, Flower R(2009).
Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1. Biochem Pharmacol
vol. 77,
(12)
1814-1826.
McArthur S, Prasongchean W, Gillies G, Solito E(2008).
A critical role for the anti-inflammatory protein annexin A1 in microglial phagocytosis. FUNDAMENTAL & CLINICAL PHARMACOLOGY
vol. 22,
23-23.
Solito E, McArthur S, Christian H, Gavins F, Buckingham JC, Gillies GE(2008).
Annexin A1 in the brain--undiscovered roles?. Trends Pharmacol Sci
vol. 29,
(3)
135-142.
McArthur S, McHale E, Gillies GE(2007).
The size and distribution of midbrain dopaminergic populations are permanently altered by perinatal glucocorticoid exposure in a sex- region- and time-specific manner. Neuropsychopharmacology
vol. 32,
(7)
1462-1476.
McArthur S, Murray HE, Dhankot A, Dexter DT, Gillies GE(2007).
Striatal susceptibility to a dopaminergic neurotoxin is independent of sex hormone effects on cell survival and DAT expression but is exacerbated by central aromatase inhibition. J Neurochem
vol. 100,
(3)
678-692.
McArthur S, Siddique Z-L, Christian HC, Capone G, Theogaraj E, John CD, Smith SF, Morris JF et al.(2006).
Perinatal glucocorticoid treatment disrupts the hypothalamo-lactotroph axis in adult female, but not male, rats. Endocrinology
vol. 147,
(4)
1904-1915.
McArthur S, McHale E, Dalley JW, Buckingham JC, Gillies GE(2005).
Altered mesencephalic dopaminergic populations in adulthood as a consequence of brief perinatal glucocorticoid exposure. J Neuroendocrinol
vol. 17,
(8)
475-482.
Gillies GE, Murray HE, Dexter D, McArthur S(2004).
Sex dimorphisms in the neuroprotective effects of estrogen in an animal model of Parkinson's disease. Pharmacol Biochem Behav
vol. 78,
(3)
513-522.