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Publications:  Dr Simon McArthur

Sheikh MH, Henson S, Loiola RA, Mercurio S, Colamatteo A, Maniscalco GT, De Rosa V, Mcarthur S et al.(2020). Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier. Journal of Neuroinflammation
10.1186/s12974-020-01810-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64712
McArthur S, Juban G, Gobbetti T, Desgeorges T, Theret M, Gondin J, Toller-Kawahisa JE, Reutelingsperger CP et al.(2020). Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation. Journal of Clinical Investigation vol. 130, (3) 1156-1167.
10.1172/JCI124635
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62847
Wickstead ES, Karim HA, Manuel RE, Biggs CS, Getting SJ, McArthur S(2020). Reversal of β-Amyloid-Induced Microglial Toxicity In Vitro by Activation of Fpr2/3. Oxid Med Cell Longev vol. 2020,
10.1155/2020/2139192
Lopez Tremoleda J, Wall J, Naganathar V, Praditsuktavorn B, Bugg O, Mcarthur S, Thiemermann C, Brohi K(2019). Modelling cardiac dysfunction following traumatic haemorrhage injury: impact on myocardial integrity. Frontiers in Immunology vol. 10,
10.3389/fimmu.2019.02774
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63503
Wan H, Li X, Ahmad U, Huang Y, Uttagomol J, Rehman A, Zhou K, Warnes G et al.(2019). Desmoglein-3 acts as a pro-survival protein by suppressing reactive oxygen species and doming whilst augmenting the tight junctions in MDCK cells. Mechanisms of Ageing and Development
10.1016/j.mad.2019.111174
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61285
Loiola RA, Wickstead ES, Solito E, Mcarthur S(2019). Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Frontiers in Endocrinology
10.3389/fendo.2019.00420
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58286
Loiola RA, Wickstead ES, Solito E, McArthur S(2019). Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Front Endocrinol (Lausanne) vol. 10,
10.3389/fendo.2019.00420
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59871
Barrios-Silva LV, Parnell M, Shinwari ZB, Chaudhary GA, Xenofontos T, van Bekhoven A, MCARTHUR S, Elliott BT(2018). Activin sub-family peptides predict chronological age in humans. Physiological Reports vol. 6, (17) e13823-e13823.
10.14814/phy2.13823
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44443
Hoyles L, Snelling T, Umlai U-K, Nicholson JK, Carding SR, Glen RC, MCARTHUR S(2018). Microbiome-host systems interactions: Protective effects of propionate upon the bloodbrain barrier. BMC Microbiome vol. 6, 55-55.
10.1186/s40168-018-0439-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38224
Bruzzi S, Sutti S, Toscani A, Bozzola C, Reutelingsperger C, Kusters D, Mcarthur S, Perretti M et al. (2017). Annexin A1 supplementation prevents the progression to fibrosis of nonalcoholic steatoepatitis (NASH). JOURNAL OF HEPATOLOGY. Conference: The International Liver Congress 2017 vol. 66, S608-S608.
10.1016/S0168-8278(17)31653-7
Virdee K, Kentrop J, Jupp B, Venus B, Hensman D, McArthur S, Wilkinson J, Robbins TW et al.(2016). Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory. Psychopharmacology (Berl) vol. 233, (21-22) 3751-3761.
10.1007/s00213-016-4405-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17763
McArthur S, Loiola RA, Maggioli, E, Errede M, Virgintino D, SOLITO E(2016). The restorative role of annexin A1 at the blood–brain barrier. Fluids and Barriers of the CNS vol. 13, (17)
10.1186/s12987-016-0043-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16229
McArthur S, Pienaar IS, Siddiqi SM, Gillies GE(2016). Sex-specific disruption of murine midbrain astrocytic and dopaminergic developmental trajectories following antenatal GC treatment. Brain Struct Funct vol. 221, (5) 2459-2475.
10.1007/s00429-015-1049-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18366
Maggioli E, McArthur S, Mauro C, Kieswich J, Kusters DHM, Reutelingsperger CPM, Yaqoob M, Solito E(2016). Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking. Brain, Behavior, and Immunity vol. 51, 212-222.
10.1016/j.bbi.2015.08.020
https://qmro.qmul.ac.uk/xmlui/handle/123456789/8781
Shende VH, McArthur S, Gillies GE, Opacka-Juffry J(2015). Astroglial Plasticity Is Implicated in Hippocampal Remodelling in Adult Rats Exposed to Antenatal Dexamethasone. Neural Plast vol. 2015,
10.1155/2015/694347
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18821
McArthur S, Gobbetti T, Kusters DHM, Reutelingsperger CP, Flower RJ, Perretti M(2015). Definition of a novel pathway centered on lysophosphatidic acid to recruit monocytes during the resolution phase of tissue inflammation. Journal of Immunology vol. 195, (3) 1139-1151.
10.4049/jimmunol.1500733
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10753
Gobbetti T, Coldewey SM, Chen J, McArthur S, Le Faouder P, Cenac N, Flower RJ, Thiemermann C et al.(2014). Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proceedings of the National Academy of Sciences of the United States of America vol. 111, (52) 18685-18690.
10.1073/pnas.1410938111
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6704
Gillies GE, Virdee K, McArthur S, Dalley JW(2014). Sex-dependent diversity in ventral tegmental dopaminergic neurons and developmental programing: A molecular, cellular and behavioral analysis. Neuroscience vol. 282, 69-85.
10.1016/j.neuroscience.2014.05.033
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18856
Virdee K, McArthur S, Brischoux F, Caprioli D, Ungless MA, Robbins TW, Dalley JW, Gillies GE(2014). Antenatal glucocorticoid treatment induces adaptations in adult midbrain dopamine neurons, which underpin sexually dimorphic behavioral resilience. Neuropsychopharmacology vol. 39, (2) 339-350.
10.1038/npp.2013.196
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18639
Locatelli I, Sutti S, Jindal A, Vacchiano M, Bozzola C, Reutelingsperger C, Kusters D, Bena S et al.(2014). Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice. Hepatology vol. 60, (2) 531-544.
10.1002/hep.27141
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10761
Thompson D, McArthur S, Hislop JN, Flower RJ, Perretti M(2014). Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: Association with cell protection from apoptosis. Journal of Biological Chemistry vol. 289, (52) 36166-36178.
10.1074/jbc.M114.612630
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19653
Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ, Perretti M(2013). Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A vol. 110, (45) 18232-18237.
10.1073/pnas.1308253110
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11983
Cash JL, Bena S, Headland SE, McArthur S, Brancaleone V, Perretti M(2013). Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep vol. 14, (11) 999-1007.
10.1038/embor.2013.138
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10074
Nadkarni S, McArthur S(2013). Oestrogen and immunomodulation: new mechanisms that impact on peripheral and central immunity. Curr Opin Pharmacol vol. 13, (4) 576-581.
10.1016/j.coph.2013.05.007
Katsouri L, Vizcaychipi MP, McArthur S, Harrison I, Suárez-Calvet M, Lleo A, Lloyd DG, Ma D et al.(2013). Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease. Neurobiol Aging vol. 34, (4) 1105-1115.
10.1016/j.neurobiolaging.2012.09.010
Cristante E, McArthur S, Mauro C, Maggioli E, Romero IA, Wylezinska-Arridge M, Couraud PO, Lopez-Tremoleda J et al.(2013). Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proc Natl Acad Sci U S A vol. 110, (3) 832-841.
10.1073/pnas.1209362110
Dalli J, Montero-Melendez T, McArthur S, Perretti M(2012). Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol vol. 3,
10.3389/fphar.2012.00028
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18353
McArthur S, Robinson IC, Gillies GE(2011). Novel ontogenetic patterns of sexual differentiation in arcuate nucleus GHRH neurons revealed in GHRH-enhanced green fluorescent protein transgenic mice. Endocrinology vol. 152, (2) 607-617.
10.1210/en.2010-0798
McArthur S, Gillies GE(2011). Peripheral vs. Central Sex Steroid Hormones in Experimental Parkinson's Disease. Front Endocrinol (Lausanne) vol. 2,
10.3389/fendo.2011.00082
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18497
McArthur S, Cristante E, Paterno M, Christian H, Roncaroli F, Gillies GE, Solito E(2010). Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. J Immunol vol. 185, (10) 6317-6328.
10.4049/jimmunol.1001095
Gillies GE, McArthur S(2010). Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines. Pharmacol Rev vol. 62, (2) 155-198.
10.1124/pr.109.002071
Yazid S, Ayoub SS, Solito E, McArthur S, Vo P, Dufton N, Flower RJ(2010). Anti-allergic drugs and the Annexin-A1 system. Pharmacol Rep vol. 62, (3) 511-517.
10.1016/s1734-1140(10)70307-8
Gillies GE, McArthur S(2010). Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson's disease: A contribution to sex-specific neuroprotection by estrogens. Horm Behav vol. 57, (1) 23-34.
10.1016/j.yhbeh.2009.06.002
McArthur S, Yazid S, Christian H, Sirha R, Flower R, Buckingham J, Solito E(2009). Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization. FASEB J vol. 23, (11) 4000-4010.
10.1096/fj.09-131391
Yazid S, Solito E, Christian H, McArthur S, Goulding N, Flower R(2009). Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1. Biochem Pharmacol vol. 77, (12) 1814-1826.
10.1016/j.bcp.2009.03.010
McArthur S, Prasongchean W, Gillies G, Solito E(2008). A critical role for the anti-inflammatory protein annexin A1 in microglial phagocytosis. FUNDAMENTAL & CLINICAL PHARMACOLOGY vol. 22, 23-23.
Solito E, McArthur S, Christian H, Gavins F, Buckingham JC, Gillies GE(2008). Annexin A1 in the brain--undiscovered roles?. Trends Pharmacol Sci vol. 29, (3) 135-142.
10.1016/j.tips.2007.12.003
McArthur S, McHale E, Gillies GE(2007). The size and distribution of midbrain dopaminergic populations are permanently altered by perinatal glucocorticoid exposure in a sex- region- and time-specific manner. Neuropsychopharmacology vol. 32, (7) 1462-1476.
10.1038/sj.npp.1301277
McArthur S, Murray HE, Dhankot A, Dexter DT, Gillies GE(2007). Striatal susceptibility to a dopaminergic neurotoxin is independent of sex hormone effects on cell survival and DAT expression but is exacerbated by central aromatase inhibition. J Neurochem vol. 100, (3) 678-692.
10.1111/j.1471-4159.2006.04226.x
McArthur S, Siddique Z-L, Christian HC, Capone G, Theogaraj E, John CD, Smith SF, Morris JF et al.(2006). Perinatal glucocorticoid treatment disrupts the hypothalamo-lactotroph axis in adult female, but not male, rats. Endocrinology vol. 147, (4) 1904-1915.
10.1210/en.2005-1496
McArthur S, McHale E, Dalley JW, Buckingham JC, Gillies GE(2005). Altered mesencephalic dopaminergic populations in adulthood as a consequence of brief perinatal glucocorticoid exposure. J Neuroendocrinol vol. 17, (8) 475-482.
10.1111/j.1365-2826.2005.01331.x
Gillies GE, Murray HE, Dexter D, McArthur S(2004). Sex dimorphisms in the neuroprotective effects of estrogen in an animal model of Parkinson's disease. Pharmacol Biochem Behav vol. 78, (3) 513-522.
10.1016/j.pbb.2004.04.022
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