Publications:  Dr Heinke Kunst

van den Elsen SH, Sturkenboom MG, Akkerman O, Barkane L, Bruchfeld J, Eather G, Heysell SK, Hurevich H et al.(2020). Prospective evaluation of improving fluoroquinolone exposure using centralised therapeutic drug monitoring (TDM) in patients with tuberculosis (PERFECT): a study protocol of a prospective multicentre cohort study. BMJ Open vol. 10, (6) e035350-e035350.

Gupta RK, Kunst H, Lipman M, Noursadeghi M, Jackson C, Southern J, Imran A, Lozewicz S et al.(2020). Evaluation of QuantiFERON-TB Gold Plus for Predicting Incident Tuberculosis among Recent Contacts: A Prospective Cohort Study. Ann Am Thorac Soc vol. 17, (5) 646-650.

Potter JL, Burman M, Tweed CD, Vaghela D, Kunst H, Swinglehurst D, Griffiths CJ(2020). The NHS visitor and migrant cost recovery programme - A threat to health?. BMC Public Health vol. 20, (1)

Migliori GB, Tiberi S, Zumla A, Petersen E, Chakaya JM, Wejse C, Muñoz Torrico M, Duarte R et al.(2020). MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network. International Journal of Infectious Diseases vol. 92, S15-S25.

Stagg HR, Abubakar I, Campbell CN, Copas A, Darvell M, Horne R, Kielmann K, Kunst H et al.(2019). IMPACT study on intervening with a manualised package to achieve treatment adherence in people with tuberculosis: protocol paper for a mixed-methods study, including a pilot randomised controlled trial. BMJ Open vol. 9, (12) e032760-e032760.

Gupta RK, Lipman M, Jackson C, Sitch A, Southern J, Drobniewski F, Deeks JJ, Tsou C-Y et al.(2019). Quantitative Interferon Gamma Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis: A Prospective Cohort Study. American Journal of Respiratory and Critical Care Medicine

Borisov S, Danila E, Maryandyshev A, Dalcolmo M, Miliauskas S, Kuksa L, Manga S, Skrahina A et al.(2019). Surveillance of adverse events in the treatment of drug-resistant tuberculosis: First global report. European Respiratory Journal vol. 54, (6)

Burman M, Copas A, Zenner D, Hickson V, Gosce L, Trathen D, Ashcroft R, Martineau AR et al.(2019). Protocol for a cluster randomised control trial evaluating the efficacy and safety of treatment for latent tuberculosis infection in recent migrants within primary care: The CATAPuLT trial. BMC Public Health vol. 19, (1)

Stagg HR, Bothamley GH, Davidson JA, Kunst H, Lalor MK, Lipman MC, Loutet MG, Lozewicz S et al.(2019). Fluoroquinolones and isoniazid-resistant tuberculosis: Implications for the 2018 WHO guidance. European Respiratory Journal vol. 54, (4)

Sundaralingam A, Kilic Y, Burman M, Rahman A, White V, Jayasekera N, Darmalingam M, Tiberi S et al. (2019). A Case Series of Pericardial TB in a large European Centre. EUROPEAN RESPIRATORY JOURNAL. vol. 54,

Gupta R, Lipman M, Jackson C, Sitch A, Southern J, Drobniewski F, Deeks J, Tsou C-Y et al. (2019). Do higher quantitative interferon gamma release assay or tuberculin skin test results help to predict incident tuberculosis? Data from the UK PREDICT study. EUROPEAN RESPIRATORY JOURNAL. vol. 54,

Lange B, Arend SM, Armbruster C, Arias-Guillen M, Bakker M, Berastegui C, Babiker M, Charif R et al. (2019). Posttransplant tuberculosis in Europe - a TBnet study. EUROPEAN RESPIRATORY JOURNAL. vol. 54,

Pang D, Skyllberg E, Waite M, Rahman A, Burman M, Tiberi S, Kunst H (2019). Unusual presentations of tuberculosis in East London. EUROPEAN RESPIRATORY JOURNAL. vol. 54,

McGuire E, Carey L, Tiberi S, Rahman A, Jayasekera N, White V, Kunst H(2019). Breast tuberculosis in East London: A 13-year retrospective observational study. Breast Journal vol. 26, 235-235.

Akkerman O, Aleksa A, Alffenaar JW, Al-Marzouqi NH, Arias-Guillén M, Belilovski E, Bernal E, Boeree MJ et al.(2019). Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study. International Journal of Infectious Diseases vol. 83, 72-76.

Takwoingi Y, Whitworth H, Rees-Roberts M, Badhan A, Partlett C, Green N, Boakye A, Lambie H et al.(2019). Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation. Health Technol Assess vol. 23, (23) 1-152.

Whitworth HS, Badhan A, Boakye AA, Takwoingi Y, Rees-Roberts M, Partlett C, Lambie H, Innes J et al.(2019). Clinical utility of existing and second-generation interferon-γ release assays for diagnostic evaluation of tuberculosis: an observational cohort study. Lancet Infect Dis vol. 19, (2) 193-202.

Shah K, Johnson E, Rahman A, McCaffferty K, Kunst H (2019). Active Tuberculosis in Patients Receiving Renal Replacement Therapy for End Stage Renal Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 199,

Tiberi S, Torrico MM, Rahman A, Krutikov M, Visca D, Silva DR, Kunst H, Migliori GB(2019). Managing severe tuberculosis and its sequelae: From intensive care to surgery and rehabilitation. Jornal Brasileiro de Pneumologia vol. 45, (2)

Stagg HR, Abbara A, Alexander E, Baker L, Booth H, Bothamley GH, Burgess H, Cosgrove C et al. (2018). INVESTIGATING THE ROLE OF FLUOROQUINOLONES IN THE TREATMENT OF ISONIAZID RESISTANT TUBERCULOSIS: IMPLICATIONS FOR THE 2018 WHO GUIDANCE. THORAX. vol. 73, A94-A95.

Gupta RK, Gosce L, Green N, Southern J, Lipman M, Kunst H, Aldridge R, White P et al. (2018). YIELD AND COST OF SCREENING FOR ACTIVE AND LATENT TUBERCULOSIS AMONG HIGH-RISK GROUPS ATTENDING LONDON EMERGENCY DEPARTMENTS. THORAX. vol. 73, A92-A92.

Zweijpfenning SMH, van Groningen H, van Ingen J, Magis-Escurra C, Boeree MJ, Wagner D, Bax H, Andrejak C et al.(2018). Clofazimine does not lead to significant QT interval prolongation: a multicentre study. Eur Respir J vol. 52, (5)

Abubakar I, Drobniewski F, Southern J, Sitch AJ, Jackson C, Lipman M, Deeks JJ, Griffiths C et al.(2018). Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study. The Lancet Infectious Diseases vol. 18, (10) 1077-1087.

Burman M, Rahman A, Bothamley G, Lange C, Kunst H (2018). From policy to practice in Europe: a TBNET survey on the delivery of LTBI screening and treatment amongst migrants. EUROPEAN RESPIRATORY JOURNAL. vol. 52,

Williams E, Potter JL, Duff F, Burman M, Tiberi S, White V, Kunst H (2018). Hepatic tuberculosis - a case series. EUROPEAN RESPIRATORY JOURNAL. vol. 52,

Rosales-Klintz S, D'ambrosio L, Centis R, Verduin R, Amicosante M, Correia AM, Cirule A, Duarte R et al. (2018). Management of tuberculosis in the European Union: a multicentre audit. EUROPEAN RESPIRATORY JOURNAL. vol. 52,

Turner RD, Birring SS, Darmalingam M, Hooper RL, Kunst H, Matos S, Bothamley GH(2018). Daily cough frequency in tuberculosis and association with household infection. Int J Tuberc Lung Dis vol. 22, (8) 863-870.

Doyle RM, Burgess C, Williams R, Gorton R, Booth H, Brown J, Bryant JM, Chan J et al.(2018). Direct whole-genome sequencing of sputum accurately identifies drug-resistant mycobacterium tuberculosis faster than MGIT culture sequencing. Journal of Clinical Microbiology vol. 56, (8)

Guglielmetti L, Tiberi S, Burman M, Kunst H, Wejse C, Togonidze T, Bothamley G, Lange C et al.(2018). QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study. Eur Respir J vol. 52, (2)

Migliori GB, Sotgiu G, Rosales-Klintz S, Centis R, D'Ambrosio L, Abubakar I, Bothamley G, Caminero JA et al.(2018). ERS/ECDC statement: European Union standards for tuberculosis care, 2017 update. European Respiratory Journal vol. 51, (5)

Günther G, van Leth F, Alexandru S, Altet N, Avsar K, Bang D, Barbuta R, Bothamley G et al.(2018). Clinical Management of Multidrug-resistant Tuberculosis in 16 European Countries. Am J Respir Crit Care Med

Loutet MG, Burman M, Jayasekera N, Trathen D, Dart S, Kunst H, Zenner D(2018). National roll-out of latent tuberculosis testing and treatment for new migrants in England: A retrospective evaluation in a high-incidence area. European Respiratory Journal vol. 51, (1)

Sobhy S, Babiker ZOE, Kunst H(2017). Authors’ reply: Effective strategies to improve maternal and perinatal outcomes for pregnant women with tuberculosis,especially those living in poverty, are urgently needed. BJOG: An International Journal of Obstetrics and Gynaecology vol. 124, (13)

Potter JL, Burman M, Tweed C, Vanghuela D, White VLC, Swinglehurst D, Griffiths CJ, Kunst H (2017). HAVE RECENT CHANGES TO HEALTH POLICIES INCREASED DIAGNOSTIC DELAY AMONGST MIGRANT PATIENTS WITH ACTIVE TB?. THORAX. vol. 72, A20-A20.

Hussain R, Petrushkin H, Barraclough C, Kunst H, Pravesio C, White VLC, Potter JL (2017). OCULAR TUBERCULOSIS: A SURVEY OF UK CLINICAL PRACTICE. THORAX. vol. 72, A86-A86.

Abubakar I, Drobniewski F, Southern J, Sitch AJ, Jackson C, Lipman M, Deeks JJ, Griffiths C et al. (2017). PROGNOSTIC VALUE OF INTERFERON GAMMA RELEASE ASSAYS AND TUBERCULIN SKIN TEST IN PREDICTING THE DEVELOPMENT OF ACTIVE TUBERCULOSIS: THE UK PREDICT TB COHORT STUDY. THORAX. vol. 72, A22-A22.

Magro M(2017). Re: Montgomery and implications for clinical practice. BJOG vol. 124, (13) 2019-2020.

Kunst H, Burman M, Arnesen TM, Fiebig L, Hergens M-P, Kalkouni O, Klinkenberg E, Orcau À et al.(2017). Tuberculosis and latent tuberculous infection screening of migrants in Europe: comparative analysis of policies, surveillance systems and results. Int J Tuberc Lung Dis vol. 21, (8) 840-851.

Kunst H(2017). Cross-border collaboration in tuberculosis prevention and care in Europe: can we do better?. Int J Tuberc Lung Dis vol. 21, (7) 717-717.

Kentley J, Ooi LJ, Potter J, Tiberi S, O'Shaughnessy T, Langmead L, Chin Aleong J, THAHA MA et al.(2017). Intestinal Tuberculosis: A Diagnostic Challenge. Tropical Medicine and International Health

Magis-Escurra C, Günther G, Lange C, Alexandru S, Altet N, Avsar K, Bang D, Barbuta R et al.(2017). Treatment outcomes of MDR-TB and HIV co-infection in Europe. Eur Respir J vol. 49, (6)

Borisov SE, Dheda K, Enwerem M, Leyet RR, D'Ambrosio L, Centis R, Sotgiu G, Tiberi S et al.(2017). Effectiveness and safety of bedaquilinecontaining regimens in the treatment of MDR- and XDR-TB: A multicentre study. European Respiratory Journal vol. 49, (5)

Longman CF, Campion T, Butler B, Suaris TD, Khanam A, Kunst H, Tiberi S, O'Keeffe SA(2017). Imaging features and diagnosis of tuberculosis of the breast. Clinical Radiology vol. 72, (3) 217-222.

Halliday A, Whitworth H, Kottoor SH, Niazi U, Menzies S, Kunst H, Bremang S, Badhan A et al.(2017). Stratification of Latent Mycobacterium tuberculosis Infection by Cellular Immune Profiling. J Infect Dis vol. 215, (9) 1480-1487.

Conway S, Pitcher A, Dart S, Vaghela D, Burman MGK, Potter J, White VLC, Tiberi S et al. (2016). HOW DO FOREIGN-BORN PATIENTS WITH TUBERCULOSIS ACCESS HEALTHCARE? A COHORT ANALYSIS OF REFERRALS FROM GENERAL PRACTICE AND THE EMERGENCY DEPARTMENT TO A TERTIARY TUBERCULOSIS SERVICE. THORAX. Conference: BTS vol. 71, A147-A147.

Sobhy S, Babiker Z, Zamora J, Khan KS, Kunst H(2016). Maternal and perinatal mortality and morbidity associated with tuberculosis during pregnancy and the postpartum period: a systematic review and meta-analysis. BJOG: An International Journal of Obstetrics and Gynaecology vol. 124, (5) 727-733.

Sotgiu G, Tiberi S, D'Ambrosio L, Centis R, Alffenaar JW, Caminero JA, Abdo Arbex M, Alarcon Guizado V et al.(2016). Faster for less: the new "shorter" regimen for multidrug-resistant tuberculosis. Eur Respir J vol. 48, (5) 1503-1507.

Günther G, Lange C, Alexandru S, Altet N, Avsar K, Bang D, Barbuta R, Bothamley G et al.(2016). Treatment Outcomes in Multidrug-Resistant Tuberculosis. N Engl J Med vol. 375, (11) 1103-1105.

Pfeffer P, Burman M, Milton V, Naidu V, Vaghela D, Kunst H (2016). Eosinophilia and predominant Th2 immune responses are rarely evident in disseminated tuberculosis. EUROPEAN RESPIRATORY JOURNAL. vol. 48,

Tiberi S, Sotgiu G, D'Ambrosio L, Centis R, Arbex MA, Arrascue EA, Alffenaar JW, Caminero JA et al.(2016). Comparison of effectiveness and safety of imipenem/clavulanate-versus meropenem/clavulanate-containing regimens in the treatment of MDR- and XDR-TB. European Respiratory Journal vol. 47, (6) 1758-1766.

Tiberi S, Sotgiu G, D'Ambrosio L, Centis R, Arbex MA, Alarcon Arrascue E, Alffenaar JW, Caminero JA et al.(2016). Effectiveness and Safety of Imipenem-Clavulanate Added to an Optimized Background Regimen (OBR) Versus OBR Control Regimens in the Treatment of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis. Clinical Infectious Diseases vol. 62, (9) 1188-1190.

Tiberi S, Payen MC, Sotgiu G, D'Ambrosio L, Guizado VA, Alffenaar JW, Arbex MA, Caminero JA et al.(2016). Effectiveness and safety of meropenem/ clavulanate-containing regimens in the treatment of MDR- and XDR-TB. European Respiratory Journal vol. 47, (4) 1235-1243.

Sobhy S, Khan K, Zahir B, Kunst H(2016). Maternal and fetal outcomes of tuberculosis during pregnancy and the postpartum period: a systematic review and meta-analysis. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY vol. 123, 112-112.

Günther G, van Leth F, Altet N, Dedicoat M, Duarte R, Gualano G, Kunst H, Muylle I et al.(2015). Beyond multidrug-resistant tuberculosis in Europe: a TBNET study. Int J Tuberc Lung Dis vol. 19, (12) 1524-1527.

Macpherson L, Cuthbert R, Potter J, White V, Jayasera N, Kunst H (2015). CENTRAL NERVOUS SYSTEM TUBERCULOSIS: DIAGNOSTIC DIFFICULTIES. THORAX. vol. 70, A208-A209.

Liddicoat H, Mohd-Afzal S, Potter J, White V, Jayasekera N, Darmalingam M, Kunst H (2015). ISONIAZID AND MULTI-DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS: THE EAST LONDON EXPERIENCE. THORAX. vol. 70, A205-A205.

Butler BJ, Khanam A, White VLC, Jayasekera N, Potter JL, Kunst H (2015). MODERN DAY SCROFULOUS SWELLINGS: BREAST TUBERCULOSIS IN EAST LONDON. THORAX. vol. 70, A207-A208.

Sobhy S, Khan K, Kunst H (2015). Maternal and fetal outcomes of tuberculosis during pregnancy and the postpartum period: a systematic review and meta-analysis. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. vol. 122, 61-61.

Burman MGK, Ahmed G, Potter JL, White VLC, Jayasekera N, Kunst H (2015). PRELIMINARY RESULTS OF A LATENT TUBERCULOSIS SCREENING AND TREATMENT PROJECT AND THE ROLE OF TB SERVICES IN SECONDARY CARE. THORAX. vol. 70, A26-A26.

Ismail I, Carey M, Trotter S, Kunst H(2015). Mycobacterial spindle cell pseudotumour of the brain in a patient with sarcoidosis. BMJ Case Rep vol. 2015,

Günther G, van Leth F, Alexandru S, Altet N, Avsar K, Bang D, Barbuta R, Bothamley G et al.(2015). Multidrug-resistant tuberculosis in Europe, 2010-2011. Emerg Infect Dis vol. 21, (3) 409-416.

Munang ML, Browne C, Khanom S, Evans JT, Grace Smith E, Hawkey PM, Kunst H, Welch SB et al.(2015). Tuberculosis microepidemics among dispersed migrants, Birmingham, UK, 2004–2013. Emerging Infectious Diseases vol. 21, (3) 524-527.

Ooi JLS, Tai FWD, Wong SD, THAHA MA, Potter JS, White VLC, Kunst H (2014). Diagnosis of abdominal tuberculosis in East London, UK. European Respiratory Journal. Conference: European Respiratory Society, 22nd Annual Congress (Munich, Germany) from: 06/09/2014 to: 10/09/2014, vol. 44,

Denneny EK, Macavei VM, Rolls S, Ma C, Jayasekera NP, O'Shaughnessy TC, Potter VLC, White VLC et al. (2014). ADVERSE EFFECTS OF LATENT TUBERCULOSIS TREATMENT IN MIGRANTS. THORAX. vol. 69, A208-A208.

Ma CY, Potter JL, Kunst H, White VLC (2014). ASIDE FROM AGE, DO OTHER FACTORS INCREASE THE RISK OF HEPATOTOXICITY IN PATIENTS TREATED FOR LATENT TB INFECTION?. THORAX. vol. 69, A160-A161.

Potter JL, Leddy SG, Kunst H, White VLC (2014). FEMALE GENITAL TUBERCULOSIS: THE LONG ROAD TO DIAGNOSIS. THORAX. vol. 69, A156-A157.

Potter JL, Hyams C, Shaukat M, Babiker ZO, Macavei VM, Jayasekera N, Kunst H, Foster GR et al. (2014). SHOULD SCREENING FOR CHRONIC VIRAL HEPATITIS IN PATIENTS WITH TUBERCULOSIS BE INTRODUCED TO NICE GUIDELINES?. THORAX. vol. 69, A159-A159.

Denneny EK, Black SE, Bogle Y, Macavei VM, O'Shaughnessy TC, White VLC, Kunst H, Jayasekera NP (2014). TACKLING POOR ATTENDANCE TO TUBERCULOSIS CLINIC - WHO, WHY AND WHAT CAN BE DONE. THORAX. vol. 69, A210-A210.

Potter JL, Agrawal R, Barradough C, Rahman F, Kunst H, Westcott M (2014). THE USE OF MOXIFLOXACIN FOR THE TREATMENT OF OPHTHALMIC TUBERCULOSIS. THORAX. vol. 69, A158-A158.

Browne C, Munang ML, Evans JS, Smith EG, Khanom S, Hawkey P, Kunst H, Welch S et al. (2013). IMPACT OF TB CLUSTER INVESTIGATION IN A NEW MIGRANT COMMUNITY. THORAX. vol. 68, A119-A119.

Munang ML, Browne C, Khanom S, Smith EG, Evans JS, Hawkey P, Kunst H, Welch S et al. (2013). INCORPORATING TUBERCULOSIS STRAIN TYPING DATA INTO ROUTINE CONTACT TRACING INVESTIGATIONS: EXPERIENCE FROM THE FIELD. THORAX. vol. 68, A116-A116.

Kunst H, Khan KS(2010). Age-related risk of hepatotoxicity in the treatment of latent tuberculosis infection: A systematic review. International Journal of Tuberculosis and Lung Disease vol. 14, (11) 1374-1381.

Kunst H, Khan KS(2007). New tests for the diagnosis of latent tuberculosis infection. Annals of Internal Medicine vol. 147, (9) 672-673.

Khan KS, Honest H(2007). Risk screening for spontaneous preterm labour. Best Practice and Research: Clinical Obstetrics and Gynaecology vol. 21, (5) 821-830.

Dinnes J, Deeks J, Kunst H, Gibson A, Cummins E, Waugh N, Drobniewski F, Lalvani A(2007). A systematic review of rapid diagnostic tests for the detection of tuberculosis infection. Health Technol Assess vol. 11, (3) 1-196.

Khan KS, Coomarasamy A(2006). A hierarchy of effective teaching and learning to acquire competence in evidenced-based medicine. BMC Medical Education vol. 6,

Khan KS(2006). The architecture of evidence-based gynaecology. Best Practice and Research: Clinical Obstetrics and Gynaecology vol. 20, (5) 639-646.

Kelleher P, Goodsall A, Mulgirigama A, Kunst H, Henderson DC, Wilson R, Newman-Taylor A, Levin M(2006). Interferon-gamma therapy in two patients with progressive chronic pulmonary aspergillosis. Eur Respir J vol. 27, (6) 1307-1310.

Khan KS, Bachmann LM, Ter Riet G(2003). Systematic reviews with individual patient data meta-analysis to evaluate diagnostic tests. European Journal of Obstetrics and Gynecology and Reproductive Biology vol. 108, (2) 121-125.

Kunst H, Groot D, Latthe PM, Latthe M, Khan KS(2002). Accuracy of information on apparently credible websites: Survey of five common health topics. British Medical Journal vol. 324, (7337) 581-582.

Kunst H, Khan KS(2002). Quality of web-based medical information on stable COPD: comparison of non-commercial and commercial websites. Health information and libraries journal vol. 19, (1) 42-48.

Khan KS, Dinnes J, Kleijnen J(2001). Systematic reviews to evaluate diagnostic tests. European Journal of Obstetrics and Gynecology and Reproductive Biology vol. 95, (1) 6-11.

Khan KS, Dwarakanath LS, Pakkal M, Brace V, Awonuga A(1999). Postgraduate journal club as a means of evidence-based obstetrics and gynaecology. Journal of Obstetrics and Gynaecology vol. 19, (3) 231-234.

Khan KS, Chien PFW, Dwarakanath LS(1999). Logistic regression models in obstetrics and gynecology literature. Obstetrics and Gynecology vol. 93, (6) 1014-1020.