Publications: Prof Susana Alves Godinho

Fu H, Vuononvirta J, Fanti S, Bonacina F, D’Amati A, Wang G, Poobalasingam T, Fankhaenel M et al. ( 2023 ) . The Glucose Transporter 2 regulates CD8+ T cell function via environment sensing . Nature Metabolism

Monteiro P, Yeon B, Wallis SS, Godinho SA ( 2023 ) . Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization . The EMBO Journal vol. 42 , ( 16 )

Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S et al. ( 2023 ) . Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening . Disease Models & Mechanisms vol. 16 , ( 2 )

Wallis SS, Godinho SA ( 2023 ) . Regulation of microtubule acetylation during the DNA damage response promotes efficient repair . MOLECULAR BIOLOGY OF THE CELL . vol. 34 , 336 - 337 .

Donker L, Godinho SA ( 2022 ) . Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes . Journal of Cell Biology vol. 221 , ( 6 )

Adams SD, Csere J, D’angelo G, Carter EP, Romao M, Arnandis T, Dodel M, Kocher HM et al. ( 2021 ) . Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption . Current Biology vol. 31 , ( 7 ) 1403 - 1416.e7 .

Adams SD, Csere J, D’angelo G, Carter EP, Arnandis T, Dodel M, Kocher H, Grose R et al. ( 2020 ) . Centrosome amplification mediates small extracellular vesicles secretion via lysosome disruption .

Wilcz‐Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R et al. ( 2020 ) . Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway . EMBO Molecular Medicine vol. 12 , ( 2 )

( 2019 ) . Early Career Advisory Board . Journal of Cell Biology vol. 218 , ( 9 ) 2813 - 2814 .

Marat A ( 2019 ) . Early Career Advisory Board: Q&A on career and publishing . Journal of Cell Biology vol. 218 , ( 9 ) 2815 - 2818 .

Godinho SA ( 2019 ) . The principles of spindle bipolarity . Nature Reviews Molecular Cell Biology vol. 20 , ( 6 ) 325 - 325 .

Arnandis T, Monteiro P, Adams SD, Bridgeman VL, Rajeeve V, Gadaleta E, Marzec J, Chelala C et al. ( 2018 ) . Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion . Developmental Cell vol. 47 , ( 4 ) 409 - 424.e9 .

Monteiro P, Godinho SA ( 2018 ) . Structural Centrosomal Abnormalities Push Cells toward Invasion . Developmental Cell vol. 45 , ( 3 ) 286 - 288 .

Marteil G, Guerrero A, Vieira AF, de Almeida BP, Machado P, Mendonça S, Mesquita M, Villarreal B et al. ( 2018 ) . Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation . Nature Communications vol. 9 , ( 1 )

( 2018 ) . Cell scientist to watch – Susana Godinho . Journal of Cell Science vol. 131 , ( 4 )

Rhys AD, Monteiro P, Smith C, Vaghela M, Arnandis T, Kato T, Leitinger B, Sahai E et al. ( 2017 ) . Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells . J Cell Biol vol. 217 , ( 1 ) 195 - 209 .

Rhys AD, Godinho SA ( 2017 ) . Dividing with Extra Centrosomes: A Double Edged Sword for Cancer Cells . Adv Exp Med Biol vol. 1002 , 47 - 67 .

Godinho S ( 2017 ) . Centrosomes: PIDDosome Joins the Counting Game . Current Biology vol. 27 , ( 6 ) r237 - r239 .

Rhys AD, Vaghela M, Monteiro P, Yusuf M, McAinsh AD, Charras G, Godinho SA ( 2016 ) . DDR1 localisation to adherens junctions prevents efficient clustering of supernumerary centrosomes . MOLECULAR BIOLOGY OF THE CELL . vol. 27 ,

Arnandis T, Rajeeve V, Brennan CH, Cutillas PR, Godinho SA ( 2016 ) . Paracrine-mediated invasion induced by centrosome amplification . MOLECULAR BIOLOGY OF THE CELL . vol. 27 ,

Arnandis T, Godinho SA ( 2015 ) . Chapter 3 Studying centrosome function using three-dimensional cell cultures . Methods in Cell Biology vol. 129 , 37 - 50 .

Gibbons JG, Branco AT, Godinho SA, Yu S, Lemos B ( 2015 ) . Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes . Proceedings of the National Academy of Sciences of the United States of America vol. 112 , ( 8 ) 2485 - 2490 .

Marteil G, Guerrero A, Godinho S, Machado P, Loncarek J, Mendonca S, Fonseca I, Pellman D et al. ( 2014 ) . Cancer-wide survey of centrosomes reveals centriole fragmentation as a novel origin of supernumerary centrosomes . MOLECULAR BIOLOGY OF THE CELL . vol. 25 ,

Godinho SA ( 2014 ) . Centrosome amplification and cancer: Branching out . Molecular & Cellular Oncology vol. 2 , ( 1 )

Godinho SA, Kwon M, Ganem NJ, Pellman D ( 2009 ) . Abstract C65: Mechanisms to maintain extra centrosomes in cancer cells . Cancer Research . vol. 69 , c65 - c65 .

Godinho SA, Pellman D ( 2014 ) . Causes and consequences of centrosome abnormalities in cancer . Philos Trans R Soc Lond B Biol Sci vol. 369 , ( 1650 )

Godinho SA, Picone R, Burute M, Dagher R, Su Y, Leung CT, Polyak K, Brugge JS et al. ( 2014 ) . Oncogene-like induction of cellular invasion from centrosome amplification . Nature vol. 510 , ( 7503 ) 167 - 171 .

Marteil G, Guerrero A, Godinho S, Machado P, Loncarek J, Mendonca S, Fonseca I, Pellman D et al. ( 2014 ) . Cancer-wide survey of centrosomes reveals centriole fragmentation as a novel origin of supernumerary centrosomes . MOLECULAR BIOLOGY OF THE CELL . vol. 25 ,

Calado DP, Sasaki Y, Godinho SA, Pellerin A, Köchert K, Sleckman BP, de Alborán IM, Janz M et al. ( 2012 ) . The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers . Nat Immunol vol. 13 , ( 11 ) 1092 - 1100 .

Bettencourt-Dias M, Hildebrandt F, Pellman D, Woods G, Godinho SA ( 2011 ) . Centrosomes and cilia in human disease . Trends Genet vol. 27 , ( 8 ) 307 - 315 .

Parmar K, Vinciguerra P, Godinho S, Hamilton A, Pellman D, D'Andrea AD ( 2010 ) . Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells . Blood vol. 116 , ( 21 )

Vinciguerra P, Godinho SA, Parmar K, Pellman D, D'Andrea AD ( 2010 ) . Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells . J Clin Invest vol. 120 , ( 11 ) 3834 - 3842 .

Parmar K, Vinciguerra P, Godinho S, Hamilton A, Pellman D, D'Andrea AD ( 2010 ) . Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells . BLOOD . vol. 116 , 385 - 385 .

Vinciguerra P, Godinho S, Parmar K, Pellman D, D'Andrea A ( 2009 ) . Cytokinesis Failure in Fanconi Anemia Pathway Deficient Murine Hematopoietic Stem Cells . Blood vol. 114 , ( 22 )

Ganem NJ, Godinho SA, Pellman D ( 2009 ) . A mechanism linking extra centrosomes to chromosomal instability . Nature vol. 460 , ( 7252 ) 278 - 282 .

Godinho SA, Kwon M, Pellman D ( 2009 ) . Centrosomes and cancer: how cancer cells divide with too many centrosomes . Cancer Metastasis Rev vol. 28 , ( 1-2 ) 85 - 98 .

Vinciguerra P, Godinho S, Parmar K, Pellman D, D'Andrea A ( 2009 ) . Cytokinesis Failure in Fanconi Anemia Pathway Deficient Murine Hematopoietic Stem Cells . BLOOD . vol. 114 , 204 - 205 .

Godinho S, Tavares AA ( 2008 ) . A role for Drosophila Polo protein in chromosome resolution and segregation during mitosis . Cell Cycle vol. 7 , ( 16 ) 2529 - 2534 .

Kwon M, Godinho SA, Chandhok NS, Ganem NJ, Azioune A, Thery M, Pellman D ( 2008 ) . Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes . Genes Dev vol. 22 , ( 16 ) 2189 - 2203 .

Schüller U, Zhao Q, Godinho SA, Heine VM, Medema RH, Pellman D, Rowitch DH ( 2007 ) . Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors . Mol Cell Biol vol. 27 , ( 23 ) 8259 - 8270 .

Pearson J, Godinho SA, Tavares A, Glover DM ( 2006 ) . Heterologous expression of mammalian Plk1 in Drosophila reveals divergence from Polo during late mitosis . Exp Cell Res vol. 312 , ( 6 ) 770 - 781 .

Alves PS, Godinho SA, Tavares AA ( 2006 ) . The Drosophila orthologue of xPlkk1 is not essential for Polo activation and is necessary for proper contractile ring formation . Exp Cell Res vol. 312 , ( 3 ) 308 - 321 .

Godinho SA, Alves P, Parelho V, Tavares A ( 2002 ) . Cloning and characterization of <i>Drosophila</i> polo kinase kinase, dPlkk . MOLECULAR BIOLOGY OF THE CELL . vol. 13 , 167A - 167A .