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Publications:  Dr Amy Lewis

Rigoni A, Poulsom R, Jeffery R, Mehta S, Lewis A, Yau C, Giannoulatou E, Feakins R et al.(2017). Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans. Inflamm Bowel Dis vol. 24, (1) 136-148.
Adam J, Ramracheya R, Chibalina MV, Ternette N, Hamilton A, Tarasov AI, Zhang Q, Rebelato E et al.(2017). Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes. Cell Rep vol. 20, (13) 3135-3148.
Lewis A, Felice C, Kumagai T, Lai C, Singh K, Jeffery RR, Feakins R, Giannoulatou E et al.(2017). The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients. PLoS One vol. 12, (3) e0173664-e0173664.
Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, Bundy JG, Tomoyoshi S et al.(2017). Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance. Human Molecular Genetics
Walton S-J, Lewis A, Jeffery R, Thompson H, Feakins R, Giannoulatou E, Yau C, Lindsay JO et al.(2016). Familial adenomatous patients with desmoid tumours show increased expression of miR-34a in serum and high levels in tumours. Oncoscience vol. 3, (5-6) 173-185.
Rigoni A, Bongiovanni L, Burocchi A, Sangaletti S, Danelli L, Guarnotta C, Lewis A, Rizzo A et al.(2015). Mast cells infiltrating inflamed or transformed gut alternatively sustain mucosal healing or tumor growth. Cancer Research vol. 75, (18) 3760-3770.
Lewis A, Nijhuis A, Mehta S, Kumagai T, Feakins R, Lindsay JO, Silver A(2015). Intestinal fibrosis in crohn's disease: Role of microRNAs as fibrogenic modulators, serum biomarkers, and therapeutic targets. Inflammatory Bowel Diseases vol. 21, (5) 1141-1150.
Lewis A, Mehta S, Hanna LN, Rogalski LA, Jeffery R, Nijhuis A, Kumagai T, Biancheri P et al.(2015). Low serum levels of microRNA-19 are associated with a stricturing Crohn's disease phenotype. Inflammatory Bowel Diseases vol. 21, (8) 1926-1934.
Felice C, Lewis A, Armuzzi A, Lindsay JO, Silver A(2015). Review article: selective histone deacetylase isoforms as potential therapeutic targets in inflammatory bowel diseases. Aliment Pharmacol Ther vol. 41, (1) 26-38.
Shrikrishna D, Tanner RJ, Lee JY, Natanek A, Lewis A, Murphy PB, Hart N, Moxham J et al.(2014). A randomized controlled trial of angiotensin-converting enzyme inhibition for skeletal muscle dysfunction in COPD. Chest vol. 146, (4) 932-940.
Nijhuis A, Biancheri P, Lewis A, Bishop CL, Giuffrida P, Chan C, Feakins R, Poulsom R et al.(2014). In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts. Clin Sci (Lond) vol. 127, (5) 341-350.
Donaldson A, Natanek SA, Lewis A, Man WD-C, Hopkinson NS, Polkey MI, Kemp PR(2013). Increased skeletal muscle-specific microRNA in the blood of patients with COPD. Thorax vol. 68, (12) 1140-1149.
Lewis A, Riddoch-Contreras J, Natanek SA, Donaldson A, Man WD-C, Moxham J, Hopkinson NS, Polkey MI et al.(2012). Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD. Thorax vol. 67, (1) 26-34.
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