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Publications:  Dr Oliver Pearce

Wight TN, Kang I, Evanko SP, Harten IA, Chang MY, Pearce OMT, Allen CE, Frevert CW(2020). Versican—A Critical Extracellular Matrix Regulator of Immunity and Inflammation. Frontiers in Immunology vol. 11,
10.3389/fimmu.2020.00512
Maniati E, Berlato C, Gopinathan G, Heath O, Kotantaki P, Lakhani A, McDermott J, Pegrum C et al.(2020). Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment. Cell Reports vol. 30, (2) 525-540.e7.
10.1016/j.celrep.2019.12.034
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62723
Pearce OMT, Läubli H(2018). Cancer Immunotherapy. Glycobiology vol. 28, (9) 638-639.
10.1093/glycob/cwy069
Pearce OM(2018). Cancer glycan epitopes: biosynthesis, structure, and function. Glycobiology
10.1093/glycob/cwy023
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36589
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al.(2017). Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov
10.1158/2159-8290.CD-17-0284
https://qmro.qmul.ac.uk/xmlui/handle/123456789/30984
Bergfeld AK, Lawrence R, Diaz SL, Pearce OMT, Ghaderi D, Gagneux P, Leakey MG, Varki A(2017). N-glycolyl groups of nonhuman chondroitin sulfates survive in ancient fossils. Proc Natl Acad Sci U S A vol. 114, (39) E8155-E8164.
10.1073/pnas.1706306114
https://qmro.qmul.ac.uk/xmlui/handle/123456789/29583
Naba A, Pearce OMT, Del Rosario A, Ma D, Ding H, Rajeeve V, Cutillas PR, Balkwill FR et al.(2017). Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics. Journal of Proteome Research vol. 16, (8) 3083-3091.
10.1021/acs.jproteome.7b00191
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25021
Montfort A, Pearce OMT, Maniati E, Vincent B, Bixby LM, Bo hm S, Dowe T, Wilkes EH et al.(2016). A strong B cell response is part of the immune landscape in human high-grade serous ovarian metastases. Clinical Cancer Research
10.1158/1078-0432.CCR-16-0081
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13383
BALKWILL F, Anne Montfort, Oliver Pearce(2016). Neoadjuvant chemotherapy modulates the immune microenvironment in metastases of tubo-ovarian high-grade serous carcinoma. Clinical Cancer Research
10.1158/1078-0432.CCR-15-2657
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13991
Pearce OMT, Läubli H(2016). Sialic acids in cancer biology and immunity. Glycobiology vol. 26, (2) 111-128.
10.1093/glycob/cwv097
Gopinathan G, Milagre C, Pearce OMT, Reynolds LE, Hodivala-Dilke K, Leinster DA, Zhong H, Hollingsworth RE et al.(2015). Interleukin-6 stimulates defective angiogenesis. Cancer Research vol. 75, (15) 3098-3107.
10.1158/0008-5472.CAN-15-1227
Sumida M, Hane M, Yabe U, Shimoda Y, Pearce OMT, Kiso M, Miyagi T, Sawada M et al.(2015). Rapid Trimming of Cell Surface Polysialic Acid (PolySia) by Exovesicular Sialidase Triggers Release of Preexisting Surface Neurotrophin. J Biol Chem vol. 290, (21) 13202-13214.
10.1074/jbc.M115.638759
Schwarz F, Pearce OMT, Wang X, Samraj AN, Läubli H, Garcia JO, Lin H, Fu X et al.(2015). Siglec receptors impact mammalian lifespan by modulating oxidative stress. Elife vol. 4,
10.7554/eLife.06184
https://qmro.qmul.ac.uk/xmlui/handle/123456789/30306
Pearce OMT, Samraj AN, Läubli H, Varki NM, Varki A(2015). Reply to Mackenzie: A comparison of Neu5Gc and α-gal xenoantigens. Proc Natl Acad Sci U S A vol. 112, (12)
10.1073/pnas.1500880112
Samraj AN, Pearce OMT, Läubli H, Crittenden AN, Bergfeld AK, Banda K, Gregg CJ, Bingman AE et al.(2015). A red meat-derived glycan promotes inflammation and cancer progression. Proc Natl Acad Sci U S A vol. 112, (2) 542-547.
10.1073/pnas.1417508112
Laeubli H, Pearce OMT, Schwarz F, Deng L, Stanczak M, Deng L, Verhagen A, Secrest P et al. (2014). Engagement of myelomonocytic siglecs by tumor-associated ligands modulates innate immune responses to cancer. CANCER RESEARCH. vol. 74,
10.1158/1538-7445.AM2014-3659
Pearce OMT, Laeubli H, Verhagen A, Secrest P, Zhang J, Crocker PR, Varki N, Bui J et al. (2014). Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies. CANCER RESEARCH. vol. 74,
10.1158/1538-7445.AM2014-1063
Läubli H, Pearce OMT, Schwarz F, Siddiqui SS, Deng L, Stanczak MA, Deng L, Verhagen A et al.(2014). Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer. Proc Natl Acad Sci U S A vol. 111, (39) 14211-14216.
10.1073/pnas.1409580111
Pearce OMT, Läubli H, Verhagen A, Secrest P, Zhang J, Varki NM, Crocker PR, Bui JD et al.(2014). Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies. Proc Natl Acad Sci U S A vol. 111, (16) 5998-6003.
10.1073/pnas.1209067111
Pearce OM, Läubli H, Bui J, Varki A(2014). Hormesis in cancer immunology: Does the quantity of an immune reactant matter?. Oncoimmunology vol. 3,
10.4161/onci.29312
https://qmro.qmul.ac.uk/xmlui/handle/123456789/30963
Buchlis G, Odorizzi P, Soto PC, Pearce OMT, Hui DJ, Jordan MS, Varki A, Wherry EJ et al.(2013). Enhanced T cell function in a mouse model of human glycosylation. J Immunol vol. 191, (1) 228-237.
10.4049/jimmunol.1202905
Bergfeld AK, Diaz SL, Lawrence R, Pearce OMT, Esko JD, Varki A (2012). Natural occurrence of N-glycolyl-hexosamines in chondroitin/dermatan sulfates in mammalian tissues, derived from the metabolism of N-glycolylneuraminic acid. GLYCOBIOLOGY. vol. 22, 1539-1539.
Bergfeld AK, Pearce OMT, Diaz SL, Pham T, Varki A(2012). Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem vol. 287, (34) 28865-28881.
10.1074/jbc.M112.363549
Bergfeld AK, Pearce OMT, Diaz SL, Lawrence R, Vocadlo DJ, Choudhury B, Esko JD, Varki A(2012). Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamine. J Biol Chem vol. 287, (34) 28898-28916.
10.1074/jbc.M112.363499
Davies LRL, Pearce OMT, Tessier MB, Assar S, Smutova V, Pajunen M, Sumida M, Sato C et al.(2012). Metabolism of vertebrate amino sugars with N-glycolyl groups: resistance of α2-8-linked N-glycolylneuraminic acid to enzymatic cleavage. J Biol Chem vol. 287, (34) 28917-28931.
10.1074/jbc.M112.365056
Bergfeld AK, Pearce OMT, Diaz S, Pham T, Varki A (2012). Intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. FASEB JOURNAL. vol. 26,
Pearce OMT, Varki A(2010). Chemo-enzymatic synthesis of the carbohydrate antigen N-glycolylneuraminic acid from glucose. Carbohydr Res vol. 345, (9) 1225-1229.
10.1016/j.carres.2010.04.003
Pearce OMT, Fisher KD, Humphries J, Seymour LW, Smith A, Davis BG(2005). Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. Angew Chem Int Ed Engl vol. 44, (7) 1057-1061.
10.1002/anie.200461832
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