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Publications:  Dr Oliver Pearce

Zaghdoudi S, Decaup E, Belhabib I, Samain R, Cassant-Sourdy S, Rochotte J, Brunel A, Schlaepfer D et al.(2020). FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer. EMBO Molecular Medicine vol. 12, (11)
Wight TN, Kang I, Evanko SP, Harten IA, Chang MY, Pearce OMT, Allen CE, Frevert CW(2020). Versican—A Critical Extracellular Matrix Regulator of Immunity and Inflammation. Frontiers in Immunology vol. 11,
Maniati E, Berlato C, Gopinathan G, Heath O, Kotantaki P, Lakhani A, McDermott J, Pegrum C et al.(2020). Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment. Cell Reports vol. 30, (2) 525-540.e7.
Naba A, Pearce OMT, Del Rosario A, Ma D, Ding H, Rajeeve V, Cutillas PR, Balkwill FR et al.(2018). Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics. Journal of Proteome Research vol. 16, (8) 3083-3091.
Pearce OMT, Läubli H(2018). Cancer Immunotherapy. Glycobiology vol. 28, (9) 638-639.
Pearce OM(2018). Cancer glycan epitopes: biosynthesis, structure, and function. Glycobiology
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al.(2017). Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov
Bergfeld AK, Lawrence R, Diaz SL, Pearce OMT, Ghaderi D, Gagneux P, Leakey MG, Varki A(2017). N-glycolyl groups of nonhuman chondroitin sulfates survive in ancient fossils. Proc Natl Acad Sci U S A vol. 114, (39) E8155-E8164.
Montfort A, Pearce OMT, Maniati E, Vincent B, Bixby LM, Bo hm S, Dowe T, Wilkes EH et al.(2016). A strong B cell response is part of the immune landscape in human high-grade serous ovarian metastases. Clinical Cancer Research
BALKWILL F, Anne Montfort, Oliver Pearce(2016). Neoadjuvant chemotherapy modulates the immune microenvironment in metastases of tubo-ovarian high-grade serous carcinoma. Clinical Cancer Research
Pearce OMT, Läubli H(2016). Sialic acids in cancer biology and immunity. Glycobiology vol. 26, (2) 111-128.
Gopinathan G, Milagre C, Pearce OMT, Reynolds L, Hodivala-Dilke K, Leinster A, Zhong H, Hollingsworth RE et al.(2015). Abstract 4162: Interleukin–6 stimulates defective angiogenesis. 4162-4162.
Gopinathan G, Milagre C, Pearce OMT, Reynolds LE, Hodivala-Dilke K, Leinster DA, Zhong H, Hollingsworth RE et al.(2015). Interleukin-6 stimulates defective angiogenesis. Cancer Research vol. 75, (15) 3098-3107.
Sumida M, Hane M, Yabe U, Shimoda Y, Pearce OMT, Kiso M, Miyagi T, Sawada M et al.(2015). Rapid Trimming of Cell Surface Polysialic Acid (PolySia) by Exovesicular Sialidase Triggers Release of Preexisting Surface Neurotrophin. J Biol Chem vol. 290, (21) 13202-13214.
Schwarz F, Pearce OMT, Wang X, Samraj AN, Läubli H, Garcia JO, Lin H, Fu X et al.(2015). Siglec receptors impact mammalian lifespan by modulating oxidative stress. Elife vol. 4,
Pearce OMT, Samraj AN, Läubli H, Varki NM, Varki A(2015). Reply to Mackenzie: A comparison of Neu5Gc and α-gal xenoantigens. Proc Natl Acad Sci U S A vol. 112, (12)
Samraj AN, Pearce OMT, Läubli H, Crittenden AN, Bergfeld AK, Banda K, Gregg CJ, Bingman AE et al.(2015). A red meat-derived glycan promotes inflammation and cancer progression. Proc Natl Acad Sci U S A vol. 112, (2) 542-547.
Pearce OMT, Läubli H, Verhagen A, Secrest P, Zhang J, Crocker PR, Varki N, Bui J et al. (2014). Abstract 1063: Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies. 1063-1063.
Läubli H, Pearce OMT, Schwarz F, Deng L, Stanczak M, Deng L, Verhagen A, Secrest P et al. (2014). Abstract 3659: Engagement of myelomonocytic siglecs by tumor-associated ligands modulates innate immune responses to cancer. 3659-3659.
Läubli H, Pearce OMT, Schwarz F, Siddiqui SS, Deng L, Stanczak MA, Deng L, Verhagen A et al.(2014). Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer. Proc Natl Acad Sci U S A vol. 111, (39) 14211-14216.
Pearce OMT, Läubli H, Verhagen A, Secrest P, Zhang J, Varki NM, Crocker PR, Bui JD et al.(2014). Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies. Proc Natl Acad Sci U S A vol. 111, (16) 5998-6003.
Pearce OM, Läubli H, Bui J, Varki A(2014). Hormesis in cancer immunology: Does the quantity of an immune reactant matter?. Oncoimmunology vol. 3,
Buchlis G, Odorizzi P, Soto PC, Pearce OMT, Hui DJ, Jordan MS, Varki A, Wherry EJ et al.(2013). Enhanced T cell function in a mouse model of human glycosylation. J Immunol vol. 191, (1) 228-237.
Bergfeld AK, Diaz SL, Lawrence R, Pearce OMT, Esko JD, Varki A (2012). Natural occurrence of N-glycolyl-hexosamines in chondroitin/dermatan sulfates in mammalian tissues, derived from the metabolism of N-glycolylneuraminic acid. GLYCOBIOLOGY. vol. 22, 1539-1539.
Bergfeld AK, Pearce OMT, Diaz SL, Pham T, Varki A(2012). Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem vol. 287, (34) 28865-28881.
Bergfeld AK, Pearce OMT, Diaz SL, Lawrence R, Vocadlo DJ, Choudhury B, Esko JD, Varki A(2012). Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamine. J Biol Chem vol. 287, (34) 28898-28916.
Davies LRL, Pearce OMT, Tessier MB, Assar S, Smutova V, Pajunen M, Sumida M, Sato C et al.(2012). Metabolism of vertebrate amino sugars with N-glycolyl groups: resistance of α2-8-linked N-glycolylneuraminic acid to enzymatic cleavage. J Biol Chem vol. 287, (34) 28917-28931.
Bergfeld AK, Pearce OMT, Diaz S, Pham T, Varki A (2012). Intracellular fate of the non‐human sialic acid N‐glycolylneuraminic acid. The FASEB Journal. vol. 26, 793.1-793.1.
Pearce OMT, Varki A(2010). Chemo-enzymatic synthesis of the carbohydrate antigen N-glycolylneuraminic acid from glucose. Carbohydr Res vol. 345, (9) 1225-1229.
Pearce OMT, Fisher KD, Humphries J, Seymour LW, Smith A, Davis BG(2005). Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. Angew Chem Int Ed Engl vol. 44, (7) 1057-1061.
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