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Publications:  Prof Panagiotis Deloukas

Villar D, Frost S, Deloukas P, Tinker A(2020). The contribution of non-coding regulatory elements to cardiovascular disease. Open biology vol. 10, (7)
10.1098/rsob.200088
Fabre MA, McKerrell T, Zwiebel M, Vijayabaskar MS, Park N, Wells PM, Rad R, Deloukas P et al.(2020). Concordance for clonal hematopoiesis is limited in elderly twins. Blood vol. 135, (4) 269-273.
10.1182/blood.2019001807
Hidalgo BA, Sofer T, Qi Q, Schneiderman N, Chen YDI, Kaplan RC, Avilés-Santa ML, North KE et al.(2019). Associations between SLC16A11 variants and diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Scientific Reports vol. 9, (1)
10.1038/s41598-018-35707-7
Allum F, Hedman ÅK, Shao X, Cheung WA, Vijay J, Guénard F, Kwan T, Simon MM et al.(2019). Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements. Nature Communications vol. 10, (1)
10.1038/s41467-019-09184-z
Merino J, Dashti HS, Li SX, Sarnowski C, Justice AE, Graff M, Papoutsakis C, Smith CE et al.(2019). Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Molecular Psychiatry vol. 24, (12) 1920-1932.
10.1038/s41380-018-0079-4
Marouli E, Del Greco MF, Astley CM, Yang J, Ahmad S, Berndt SI, Caulfield MJ, Evangelou E et al.(2019). Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease. Communications Biology vol. 2, (1)
10.1038/s42003-019-0361-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57678
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M et al.(2019). Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2). Nature Genetics vol. 51, (9) 1423-1424.
10.1038/s41588-019-0495-7
Zeng L, Ntalla I, Kessler T, Kastrati A, Erdmann J, UK Biobank CardioMetabolic Consortium CHD Working Group, Danesh J, Watkins H et al.(2019). Genetically modulated educational attainment and coronary disease risk. Eur Heart J vol. 40, (29) 2413-2420.
10.1093/eurheartj/ehz328
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2019). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x). Nature Genetics vol. 51, (7) 1191-1192.
10.1038/s41588-019-0447-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61615
Ntalla I, Kanoni S, Zeng L, Giannakopoulou O, Danesh J, Watkins H, Samani NJ, Deloukas P et al.(2019). Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases. Journal of the American College of Cardiology vol. 73, (23) 2932-2942.
10.1016/j.jacc.2019.03.512
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58416
Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ et al.(2019). Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals. Clinical Pharmacology and Therapeutics vol. 105, (6) 1477-1491.
10.1002/cpt.1323
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54767
Gonzales MM, Durazo-Arvizu RA, Sachdeva S, Unterman TG, O'Brien MJ, Gallo LC, Talavera GA, Kaplan RC et al.(2019). Associations of insulin resistance with cognition in individuals without diagnosed diabetes: Results from the Hispanic Community Health Study/Study of Latinos. Diabetes Research and Clinical Practice vol. 150, 38-47.
10.1016/j.diabres.2019.01.030
Chichetto NE, Plankey MW, Abraham AG, Sheps DS, Ennis N, Chen X, Weber KM, Shoptaw S et al.(2019). The Impact of Past and Current Alcohol Consumption Patterns on Progression of Carotid Intima-Media Thickness Among Women and Men Living with HIV Infection. Alcoholism: Clinical and Experimental Research vol. 43, (4) 695-703.
10.1111/acer.13974
Marouli E, Del Greco MF, Astley CM, Yang J, Ahmad S, Berndt SI, Caulfield MJ, Evangelou E et al.(2019). Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease. Commun Biol vol. 2, (1)
10.1038/s42003-019-0361-2
Patel RS, Schmidt AF, Tragante V, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A et al.(2019). Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events. Circ Genom Precis Med vol. 12, (4) e002471-e002471.
10.1161/CIRCGEN.119.002471
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59187
Patel RS, Tragante V, Schmidt AF, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A et al.(2019). Subsequent Event Risk in Individuals With Established Coronary Heart Disease. Circ Genom Precis Med vol. 12, (4) e002470-e002470.
10.1161/CIRCGEN.119.002470
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59198
Shaw PA, McMurray R, Butte N, Sotres-Alvarez D, Sun H, Stoutenberg M, Evenson KR, Wong WW et al.(2019). Calibration of activity-related energy expenditure in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Journal of Science and Medicine in Sport vol. 22, (3) 300-306.
10.1016/j.jsams.2018.07.021
Xie T, Gorenjak V, Stathopoulou MG, Dadé S, Marouli E, Masson C, Murray H, Lamont J et al.(2019). Epigenome-wide association study (EWAS) of blood lipids in healthy population from STANISLAS family study (SFS). International Journal of Molecular Sciences vol. 20, (5)
10.3390/ijms20051014
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58921
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M et al.(2019). Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics vol. 51, (3) 414-430.
10.1038/s41588-019-0358-2
Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL et al.(2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics vol. 51, (3) 452-469.
10.1038/s41588-018-0334-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56167
Perreira KM, Marchante AN, Schwartz SJ, Isasi CR, Carnethon MR, Corliss HL, Kaplan RC, Santisteban DA et al.(2019). Stress and Resilience: Key Correlates of Mental Health and Substance Use in the Hispanic Community Health Study of Latino Youth. Journal of Immigrant and Minority Health vol. 21, (1) 4-13.
10.1007/s10903-018-0724-7
Parrinello CM, Rudolph BJ, Lazo M, Gallo LC, Thyagarajan B, Cotler SJ, Qi Q, Seeherunvong T et al.(2019). Associations of Insulin Resistance and Glycemia with Liver Enzymes in Hispanic/Latino Youths. Journal of Clinical Gastroenterology vol. 53, (2) E46-E53.
10.1097/MCG.0000000000000946
Vackova Z, Niebisch S, Triantafyllou T, Becker J, Hess T, Kreuser N, Kanoni S, Deloukas P et al.(2019). First genotype-phenotype study reveals HLA-DQβ1 insertion heterogeneity in high-resolution manometry achalasia subtypes. United European Gastroenterology Journal vol. 7, (1) 45-51.
10.1177/2050640618804717
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59196
Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Kizer JR, Kaplan RC, Cappola AR, Cushman M et al.(2019). Association of biomarker and physiologic indices with mortality in older adults: Cardiovascular health study. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 74, (1) 114-120.
10.1093/gerona/gly075
Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C et al.(2019). Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Molecular Psychiatry
10.1038/s41380-018-0313-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55829
Melin K, Moon JY, Qi Q, Hernandez-Suarez DF, Duconge J, Hua S, Gonzalez S, Zeng D et al.(2019). Prevalence of pharmacogenomic variants affecting the efficacy of clopidogrel therapy in the Hispanic Community Health Study/Study of Latinos cohort. Pharmacogenomics vol. 20, (2) 75-83.
10.2217/pgs-2018-0148
Visvikis-Siest S, Gorenjak V, Stathopoulou MG, Petrelis AM, Weryha G, Masson C, Hiegel B, Kumar S et al.(2018). The 9th Santorini Conference: Systems Medicine, Personalised Health and Therapy. "The Odyssey from Hope to Practice", Santorini, Greece, 30 September⁻3 October 2018. J Pers Med vol. 8, (4)
10.3390/jpm8040043
González HM, Tarraf W, Jian X, Vásquez PM, Kaplan R, Thyagarajan B, Daviglus M, Lamar M et al.(2018). Apolipoprotein E genotypes among diverse middle-aged and older Latinos: Study of Latinos-Investigation of Neurocognitive Aging results (HCHS/SOL). Scientific Reports vol. 8, (1)
10.1038/s41598-018-35573-3
Kundel V, Trivieri MG, Karakatsanis NA, Robson PM, Mani V, Kizer JR, Kaplan R, Fayad Z et al.(2018). Assessment of atherosclerotic plaque activity in patients with sleep apnea using hybrid positron emission tomography/magnetic resonance imaging (PET/MRI): a feasibility study. Sleep and Breathing vol. 22, (4) 1125-1135.
10.1007/s11325-018-1646-2
Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J et al.(2018). Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nature Communications vol. 9, (1)
10.1038/s41467-018-04668-w
Natarajan P, Peloso GM, Zekavat SM, Montasser M, Ganna A, Chaffin M, Khera AV, Zhou W et al.(2018). Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nature Communications vol. 9, (1)
10.1038/s41467-018-05747-8
Tarraf W, Criqui MH, Allison MA, Wright CB, Fornage M, Daviglus M, Kaplan RC, Davis S et al.(2018). Erratum to “Ankle brachial index and cognitive function among Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos.” (Atherosclerosis (2018) 271 (61–69), (S0021915018300790) (10.1016/j.atherosclerosis.2018.02.016)). Atherosclerosis vol. 279, 133-134.
10.1016/j.atherosclerosis.2018.09.013
Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J et al.(2018). Erratum to: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (Nature Communications, (2018), 9, 1, (2606), 10.1038/s41467-018-04668-w). Nature Communications vol. 9, (1)
10.1038/s41467-018-05975-y
Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV et al.(2018). Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nature Communications vol. 9, (1)
10.1038/s41467-018-05369-0
Moon JY, Zolnik CP, Wang Z, Qiu Y, Usyk M, Wang T, Kizer JR, Landay AL et al.(2018). Gut microbiota and plasma metabolites associated with diabetes in women with, or at high risk for, HIV infection. EBioMedicine vol. 37, 392-400.
10.1016/j.ebiom.2018.10.037
Oelsner EC, Balte PP, Cassano PA, Couper D, Enright PL, Folsom AR, Hankinson J, Jacobs DR et al.(2018). Harmonization of Respiratory Data from 9 US Population-Based Cohorts. American Journal of Epidemiology vol. 187, (11) 2265-2278.
10.1093/aje/kwy139
Hanna DB, Moon JY, Haberlen SA, French AL, Palella FJ, Gange SJ, Witt MD, Kassaye S et al.(2018). Carotid artery atherosclerosis is associated with mortality in HIV-positive women and men. AIDS (London, England) vol. 32, (16) 2393-2403.
10.1097/QAD.0000000000001972
Inouye M, Abraham G, Nelson CP, Wood AM, Sweeting MJ, Dudbridge F, Lai FY, Kaptoge S et al.(2018). Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention. Journal of the American College of Cardiology vol. 72, (16) 1883-1893.
10.1016/j.jacc.2018.07.079
Fernández-Rhodes L, Howard AG, Graff M, Isasi CR, Highland HM, Young KL, Parra E, Below JE et al.(2018). Complex patterns of direct and indirect association between the transcription Factor-7 like 2 gene, body mass index and type 2 diabetes diagnosis in adulthood in the Hispanic Community Health Study/Study of Latinos. BMC Obesity vol. 5, (1)
10.1186/s40608-018-0200-x
Rangel MO, Kaplan R, Daviglus M, Schneiderman N, Hurwitz BE, Cai J, Gonzalez F, Kitzman D et al.(2018). Estimation of Incident Heart Failure Risk among US Hispanics/Latinos Using a Validated Echocardiographic Risk-Stratification Index: the Echocardiographic Study of Latinos. Journal of Cardiac Failure vol. 24, (9) 622-624.
10.1016/j.cardfail.2018.09.003
Vadrevu SK, Trbojevic-Akmacic I, Kossenkov AV, Colomb F, Giron LB, Anzurez A, Lynn K, Mounzer K et al.(2018). Frontline Science: Plasma and immunoglobulin G galactosylation associate with HIV persistence during antiretroviral therapy. Journal of Leukocyte Biology vol. 104, (3) 461-471.
10.1002/JLB.3HI1217-500R
Strizich G, Kaplan RC, Sotres-Alvarez D, Diaz KM, Daigre AL, Carnethon MR, Vidot DC, Delamater AM et al.(2018). Objectively Measured Sedentary Behavior, Physical Activity, and Cardiometabolic Risk in Hispanic Youth: Hispanic Community Health Study/Study of Latino Youth. Journal of Clinical Endocrinology and Metabolism vol. 103, (9) 3289-3298.
10.1210/jc.2018-00356
Isasi CR, Strizich GM, Kaplan R, Daviglus ML, Sotres-Alvarez D, Vidot DC, Llabre MM, Talavera G et al.(2018). The association of cardiorespiratory fitness with cardiometabolic factors, markers of inflammation, and endothelial dysfunction in Latino youth: findings from the Hispanic Community Children's Health Study/Study of Latino Youth. Annals of Epidemiology vol. 28, (9) 583-589.e3.
10.1016/j.annepidem.2018.02.007
Wang Z, Zolnik CP, Qiu Y, Usyk M, Wang T, Strickler HD, Isasi CR, Kaplan RC et al.(2018). Comparison of fecal collection methods for microbiome and metabolomics studies. Frontiers in Cellular and Infection Microbiology vol. 8, (AUG)
10.3389/fcimb.2018.00301
Mattei J, Sotres-Alvarez D, Gellman M, Castañeda SF, Hu FB, Tucker KL, Siega-Riz AM, Kaplan RC(2018). Diet quality, inflammation, and the ankle brachial index in adults with or without cardiometabolic conditions. Clinical Nutrition vol. 37, (4) 1332-1339.
10.1016/j.clnu.2017.06.003
Ndila CM, Uyoga S, Macharia AW, Nyutu G, Peshu N, Ojal J, Shebe M, Awuondo KO et al.(2018). Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study. The Lancet Haematology vol. 5, (8) e333-e345.
10.1016/S2352-3026(18)30107-8
Burkart KM, Sofer T, London SJ, Manichaikul A, Hartwig FP, Yan Q, Artigas MS, Avila L et al.(2018). A genome-wide association study in hispanics/latinos identifies novel signals for lung function the hispanic community health study/study of latinos. American Journal of Respiratory and Critical Care Medicine vol. 198, (2) 208-219.
10.1164/rccm.201707-1493OC
Qi Q, Hua S, Clish CB, Scott JM, Hanna DB, Wang T, Haberlen SA, Shah SJ et al.(2018). Plasma tryptophan-kynurenine metabolites are altered in human immunodeficiency virus infection and associated with progression of carotid artery atherosclerosis. Clinical Infectious Diseases vol. 67, (2) 235-242.
10.1093/cid/ciy053
Salazar CR, Laniado N, Mossavar-Rahmani Y, Borrell LN, Qi Q, Sotres-Alvarez D, Morse DE, Singer RH et al.(2018). Better-quality diet is associated with lower odds of severe periodontitis in US Hispanics/Latinos. Journal of Clinical Periodontology vol. 45, (7) 780-790.
10.1111/jcpe.12926
Garg PK, Biggs ML, Kaplan R, Kizer JR, Heckbert SR, Mukamal KJ(2018). Fasting and post-glucose load measures of insulin resistance and risk of incident atrial fibrillation: The Cardiovascular Health Study. Nutrition, Metabolism and Cardiovascular Diseases vol. 28, (7) 716-721.
10.1016/j.numecd.2018.02.016
Guo Y, Moon JY, Laurie CC, North KE, Sanchez-Johnsen LAP, Davis S, Yu B, Nyenhuis SM et al.(2018). Genetic predisposition to obesity is associated with asthma in US Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos. Allergy: European Journal of Allergy and Clinical Immunology vol. 73, (7) 1547-1550.
10.1111/all.13450
Fernández-Rhodes L, Malinowski JR, Wang Y, Tao R, Pankratz N, Jeff JM, Yoneyama S, Carty CL et al.(2018). The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis. PLoS ONE vol. 13, (7)
10.1371/journal.pone.0200486
Sanders JL, Guo W, O'Meara ES, Kaplan RC, Pollak MN, Bartz TM, Newman AB, Fried LP et al.(2018). Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 73, (7) 953-959.
10.1093/gerona/glx143
Moran CA, Sheth AN, Mehta CC, Hanna DB, Gustafson DR, Plankey MW, Mack WJ, Tien PC et al.(2018). The association of C-reactive protein with subclinical cardiovascular disease in HIV-infected and HIV-uninfected women. AIDS vol. 32, (8) 999-1006.
10.1097/QAD.0000000000001785
Browning SR, Browning BL, Daviglus ML, Durazo-Arvizu RA, Schneiderman N, Kaplan RC, Laurie CC(2018). Ancestry-specific recent effective population size in the Americas. PLoS Genetics vol. 14, (5)
10.1371/journal.pgen.1007385
Huckins LM, Hatzikotoulas K, Southam L, Thornton LM, Steinberg J, Aguilera-Mckay F, Treasure J, Schmidt U et al.(2018). Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Molecular Psychiatry vol. 23, (5) 1169-1180.
10.1038/mp.2017.88
Smith AJP, Deloukas P, Munroe PB(2018). Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits. Physiol Genomics
10.1152/physiolgenomics.00028.2018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39304
Tarraf W, Criqui MH, Allison MA, Wright CB, Fornage M, Daviglus M, Kaplan RC, Davis S et al.(2018). Ankle brachial index and cognitive function among Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos. Atherosclerosis vol. 271, 61-69.
10.1016/j.atherosclerosis.2018.02.016
Seyerle AA, Sitlani CM, Noordam R, Gogarten SM, Li J, Li X, Evans DS, Sun F et al.(2018). Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: The cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics Journal vol. 18, (2) 215-226.
10.1038/tpj.2017.10
Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H et al.(2018). Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article. Nature Genetics vol. 50, (4) 559-571.
10.1038/s41588-018-0084-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56153
Stathopoulou MG, Xie T, Ruggiero D, Chatelin J, Rancier M, Weryha G, Kurth MJ, Aldasoro Arguinano AA et al.(2018). A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: The VEGF Consortium. Clinical Chemistry and Laboratory Medicine vol. 56, (4) e83-e86.
10.1515/cclm-2017-0838
Saccone NL, Emery LS, Sofer T, Gogarten SM, Becker DM, Bottinger EP, Chen LS, Culverhouse RC et al.(2018). Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Nicotine and Tobacco Research vol. 20, (4) 448-457.
10.1093/ntr/ntx107
Glesby MJ, Hanna DB, Hoover DR, Shi Q, Yin MT, Kaplan R, Tien PC, Cohen M et al.(2018). Abdominal Fat Depots and Subclinical Carotid Artery Atherosclerosis in Women With and Without HIV Infection. Journal of acquired immune deficiency syndromes (1999) vol. 77, (3) 308-316.
10.1097/QAI.0000000000001606
McClain AC, Ayala GX, Sotres-Alvarez D, Siega-Riz AM, Kaplan RC, Gellman MD, Gallo LC, Horn LV et al.(2018). Frequency of intake and type of away-from- home foods consumed are associated with diet quality in the hispanic community health study/study of latinos (HCHS/SOL). Journal of Nutrition vol. 148, (3) 453-463.
10.1093/jn/nxx067
Camacho A, Tarraf W, Jimenez DE, Gallo LC, Gonzalez P, Kaplan RC, Lamar M, Khambaty T et al.(2018). Anxious Depression and Neurocognition among Middle-Aged and Older Hispanic/Latino Adults: Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Results. American Journal of Geriatric Psychiatry vol. 26, (2) 238-249.
10.1016/j.jagp.2017.06.002
Lerman S, Jung M, Arredondo EM, Barnhart JM, Cai J, Castañeda SF, Daviglus ML, Espinoza RA et al.(2018). Religiosity prevalence and its association with depression and anxiety symptoms among Hispanic/Latino adults. PLoS ONE vol. 13, (2)
10.1371/journal.pone.0185661
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R et al.(2018). Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific data vol. 5,
10.1038/sdata.2018.2
Peña MSB, Swett K, Kaplan RC, Perreira K, Daviglus M, Kansal MM, Cai J, Giachello AL et al.(2018). Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: Results from Echo-SOL. Open Heart vol. 5, (2)
10.1136/openhrt-2018-000831
Enkhmaa B, Anuurad E, Zhang W, Li CS, Kaplan R, Lazar J, Merenstein D, Karim R et al.(2018). Effect of antiretroviral therapy on allele-associated Lp(a) level in women with HIV in the Women's Interagency HIV Study. Journal of Lipid Research vol. 59, (10) 1967-1976.
10.1194/jlr.P084517
Shan Z, Clish CB, Hua S, Scott JM, Hanna DB, Burk RD, Haberlen SA, Shah SJ et al.(2018). Gut microbial-related choline metabolite trimethylamine-N-oxide is associated with progression of carotid artery atherosclerosis in HIV infection. Journal of Infectious Diseases vol. 218, (9) 1474-1479.
10.1093/infdis/jiy356
Floyd JS, Sitlani CM, Avery CL, Noordam R, Li X, Smith AV, Gogarten SM, Li J et al.(2018). Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. Pharmacogenomics Journal vol. 18, (1) 127-135.
10.1038/tpj.2016.90
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics vol. 50, (1) 26-35.
10.1038/s41588-017-0011-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34563
Kimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M, Wolf D, Ryden C et al.(2018). Regulatory CD4<sup>+</sup> T cells recognize major histocompatibility complex class II molecule-restricted peptide epitopes of apolipoprotein B. Circulation vol. 138, (11) 1130-1143.
10.1161/CIRCULATIONAHA.117.031420
Sofer T, Moon JY, Isasi CR, Qi Q, Shah NA, Kaplan RC, Kuniholm MH(2018). Relationship of genetic determinants of height with cardiometabolic and pulmonary traits in the Hispanic Community Health Study/Study of Latinos. International Journal of Epidemiology vol. 47, (6) 2059-2069.
10.1093/ije/dyy177
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2017). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet vol. 50, (5) 766-767.
10.1038/s41588-018-0082-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56697
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R et al.(2017). Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data vol. 4, 170179-170179.
10.1038/sdata.2017.179
Mozaffarian D, Dashti HS, Wojczynski MK, Chu AY, Nettleton JA, Männistö S, Kristiansson K, Reedik M et al.(2017). Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts. PLoS One vol. 12, (12) e0186456-e0186456.
10.1371/journal.pone.0186456
Dhamoon MS, Longstreth WT, Bartz TM, Kaplan RC, Elkind MSV(2017). Disability trajectories before and after stroke and myocardial infarction the Cardiovascular Health Study. JAMA Neurology vol. 74, (12) 1439-1445.
10.1001/jamaneurol.2017.2802
Mossavar-Rahmani Y, Sotres-Alvarez D, Wong WW, Loria CM, Gellman MD, Van Horn L, Alderman MH, Beasley JM et al.(2017). Erratum: Applying recovery biomarkers to calibrate self-report measures of sodium and potassium in the hispanic community health study/study of latinos (Journal of human hypertension (2017) 31 7 (462-473)). Journal of human hypertension vol. 31, (12)
10.1038/jhh.2017.74
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C et al.(2017). Exome-wide association study of plasma lipids in &gt;300,000 individuals. Nature Genetics vol. 49, (12) 1758-1766.
10.1038/ng.3977
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28624
Shendre A, Wiener HW, Irvin MR, Aouizerat BE, Overton ET, Lazar J, Liu C, Hodis HN et al.(2017). Genome-wide admixture and association study of subclinical atherosclerosis in the Women’s Interagency HIV Study (WIHS). PLoS ONE vol. 12, (12)
10.1371/journal.pone.0188725
Moon JY, Wang T, Sofer T, North KE, Isasi CR, Cai J, Gellman MD, Moncrieft AE et al.(2017). Objectively measured physical activity, sedentary behavior, and genetic predisposition to obesity in U.S. Hispanics/Latinos: Results from the hispanic community health study/study of Latinos (HCHS/SOL). Diabetes vol. 66, (12) 3001-3012.
10.2337/db17-0573
Kelso-Chichetto NE, Plankey M, Sheps DS, Abraham AG, Chen X, Shoptaw S, Kaplan RC, Post WS et al.(2017). The impact of long-term moderate and heavy alcohol consumption on incident atherosclerosis among persons living with HIV. Drug and Alcohol Dependence vol. 181, 235-241.
10.1016/j.drugalcdep.2017.09.034
Gottlieb A, Daneshjou R, DeGorter M, Bourgeois S, Svensson PJ, Wadelius M, Deloukas P, Montgomery SB et al.(2017). Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans. Genome Medicine vol. 9, (1)
10.1186/s13073-017-0495-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/29903
Greenlee H, Strizich G, Lovasi GS, Kaplan RC, Biggs ML, Li CI, Richardson J, Burke GL et al.(2017). Concordance with Prevention Guidelines and Subsequent Cancer, Cardiovascular Disease, and Mortality: A Longitudinal Study of Older Adults. American Journal of Epidemiology vol. 186, (10) 1168-1179.
10.1093/aje/kwx150
Marouli E, Kanoni S, Mamakou V, Hackinger S, Southam L, Prins B, Rentari A, Dimitriou M et al.(2017). Evaluating the glucose raising effect of established loci via a genetic risk score. PLoS One vol. 12, (11) Article 0186669, e0186669-e0186669.
10.1371/journal.pone.0186669
https://qmro.qmul.ac.uk/xmlui/handle/123456789/31465
Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH et al.(2017). An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes vol. 66, (11) 2888-2902.
10.2337/db16-1253
Diaz KM, Goldsmith J, Greenlee H, Strizich G, Qi Q, Mossavar-Rahmani Y, Vidot DC, Buelna C et al.(2017). Prolonged, Uninterrupted Sedentary Behavior and Glycemic Biomarkers among US Hispanic/Latino Adults. Circulation vol. 136, (15) 1362-1373.
10.1161/CIRCULATIONAHA.116.026858
Hu YJ, Schmidt AF, Dudbridge F, Holmes MV, Brophy JM, Tragante V, Li Z, Liao P et al.(2017). Impact of Selection Bias on Estimation of Subsequent Event Risk. Circulation: Cardiovascular Genetics vol. 10, (5)
10.1161/CIRCGENETICS.116.001616
Vásquez E, Strizich G, Isasi CR, Echeverria SE, Sotres-Alvarez D, Evenson KR, Gellman MD, Palta P et al.(2017). Is there a relationship between accelerometer-assessed physical activity and sedentary behavior and cognitive function in US Hispanic/Latino adults? The Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Preventive Medicine vol. 103, 43-48.
10.1016/j.ypmed.2017.07.024
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N et al.(2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation: Cardiovascular Genetics vol. 10, (5)
10.1161/CIRCGENETICS.117.001778
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56729
Macé A, Tuke MA, Deelen P, Kristiansson K, Mattsson H, Nõukas M, Sapkota Y, Schick U et al.(2017). CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nat Commun vol. 8, (1) 744-744.
10.1038/s41467-017-00556-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34992
Nelson CP, Goel A, Butterworth AS, Kanoni S, Webb TR, Marouli E, Zeng L, Ntalla I et al.(2017). Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nature Genetics vol. 49, (9) 1385-1391.
10.1038/ng.3913
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25185
Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J et al.(2017). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Medicine vol. 14, (9)
10.1371/journal.pmed.1002383
Brænne I, Zeng L, Willenborg C, Tragante V, Kessler T, CARDIoGRAM Consortium, CARDIoGRAMplusC4D Consortium, Willer CJ et al.(2017). Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk. PLoS One vol. 12, (8) e0182999-e0182999.
10.1371/journal.pone.0182999
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33383
Progovac AM, Chang YF, Chang CCH, Matthews KA, Donohue JM, Scheier MF, Habermann EB, Kuller LH et al.(2017). Are Optimism and Cynical Hostility Associated with Smoking Cessation in Older Women?. Annals of Behavioral Medicine vol. 51, (4) 500-510.
10.1007/s12160-016-9873-x
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA et al.(2017). A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk. Diabetes vol. 66, (7) 2019-2032.
10.2337/db16-1329
Mossavar-Rahmani Y, Sotres-Alvarez D, Wong WW, Loria CM, Gellman MD, Van Horn L, Alderman MH, Beasley JM et al.(2017). Applying recovery biomarkers to calibrate self-report measures of sodium and potassium in the Hispanic Community Health Study/Study of Latinos. Journal of Human Hypertension vol. 31, (7) 462-473.
10.1038/jhh.2016.98
Howson JMM, Zhao W, Barnes DR, Ho WK, Young R, Paul DS, Waite LL, Freitag DF et al.(2017). Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms. Nature Genetics vol. 49, (7) 1113-1119.
10.1038/ng.3874
Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG et al.(2017). Genome-wide pleiotropy between Parkinson disease and autoimmune diseases. JAMA Neurology vol. 74, (7) 780-792.
10.1001/jamaneurol.2017.0469
Hanna DB, Xu S, Melamed ML, Gonzalez F, Allison MA, Bilsker MS, Hurwitz BE, Kansal MM et al.(2017). Association of Albuminuria With Cardiac Dysfunction in US Hispanics/Latinos. American Journal of Cardiology vol. 119, (12) 2073-2080.
10.1016/j.amjcard.2017.03.039
Saleheen D, Zhao W, Young R, Nelson CP, Ho W, Ferguson JF, Rasheed A, Ou K et al.(2017). Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. Circulation vol. 135, (24) 2336-2353.
10.1161/CIRCULATIONAHA.116.022069
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36324
Panoutsopoulou K, Thiagarajah S, Zengini E, Day-Williams AG, Ramos YF, Meessen JM, Huetink K, Nelissen RG et al.(2017). Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis. Ann Rheum Dis vol. 76, (7) 1199-1206.
10.1136/annrheumdis-2016-210373
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35446
Visvikis-Siest S, Aldasoro Arguinano AA, Stathopoulou M, Xie T, Petrelis A, Weryha G, Froguel P, Meier-Abt P et al.(2017). 8th Santorini Conference: Systems medicine and personalized health and therapy, Santorini, Greece, 3-5 October 2016. Drug Metabolism and Personalized Therapy vol. 32, (2) 119-127.
10.1515/dmpt-2017-0011
Geissler JM, Nalls M, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J et al.(2017). No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs. ADHD Attention Deficit and Hyperactivity Disorders vol. 9, (2) 121-127.
10.1007/s12402-017-0219-8
Wang X, Strizich G, Hua S, Sotres-Alvarez D, Buelna C, Gallo LC, Gellman MD, Mossavar-Rahmani Y et al.(2017). Objectively measured sedentary time and cardiovascular risk factor control in US Hispanics/Latinos with diabetes mellitus: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Journal of the American Heart Association vol. 6, (6)
10.1161/JAHA.116.004324
Leigh JA, Kaplan RC, Swett K, Balfour P, Kansal MM, Talavera GA, Perreira K, Blaha MJ et al.(2017). Smoking intensity and duration is associated with cardiac structure and function: The ECHOcardiographic Study of Hispanics/Latinos. Open Heart vol. 4, (2)
10.1136/openhrt-2017-000614
Ben-Avraham D, Govindaraju DR, Budagov T, Fradin D, Durda P, Liu B, Ott S, Gutman D et al.(2017). The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. Science Advances vol. 3, (6)
10.1126/sciadv.1602025
Zhang JE, Klein K, Jorgensen AL, Francis B, Alfirevic A, Bourgeois S, Deloukas P, Zanger UM et al.(2017). Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response. Front Pharmacol vol. 8, 323-323.
10.3389/fphar.2017.00323
https://qmro.qmul.ac.uk/xmlui/handle/123456789/29923
Song C, Burgess S, Eicher JD, O'Donnell CJ, Johnson AD, Huang J, Sabater-Lleal M, Asselbergs FW et al.(2017). Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease. Journal of the American Heart Association vol. 6, (6)
10.1161/JAHA.116.004918
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25717
Qureshi WT, Kaplan RC, Swett K, Burke G, Daviglus M, Jung M, Talavera GA, Chirinos DA et al.(2017). American College of Cardiology/American Heart Association (ACC/AHA) class I guidelines for the treatment of cholesterol to reduce atherosclerotic cardiovascular risk: Implications for US Hispanics/Latinos based on findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Journal of the American Heart Association vol. 6, (5)
10.1161/JAHA.116.005045
Parrinello CM, Hua S, Carnethon MR, Gallo LC, Hudson BI, Goldberg RB, Delamater AM, Kaplan RC et al.(2017). Associations of hyperglycemia and insulin resistance with biomarkers of endothelial dysfunction in Hispanic/Latino youths: Results from the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth). Journal of Diabetes and its Complications vol. 31, (5) 836-842.
10.1016/j.jdiacomp.2017.01.019
Jerschow E, Strizich G, Xue X, Hudes G, Spivack S, Persky V, Ayala GX, Delamater A et al.(2017). Effect of Relocation to the U.S. on Asthma Risk Among Hispanics. American Journal of Preventive Medicine vol. 52, (5) 579-588.
10.1016/j.amepre.2016.12.018
Qi Q, Stilp AM, Sofer T, Moon JY, Hidalgo B, Szpiro AA, Wang T, Ng MCY et al.(2017). Genetics of type 2 diabetes in U.S. Hispanic/Latino individuals: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Diabetes vol. 66, (5) 1419-1425.
10.2337/db16-1150
Enkhmaa B, Anuurad E, Zhang W, Li CS, Kaplan R, Lazar J, Merenstein D, Karim R et al.(2017). Lipoprotein(a) and HIV: Allele-specific apolipoprotein(a) levels predict carotid intima-media thickness in hiv-infected young women in the women's interagency HIV study. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 37, (5) 997-1004.
10.1161/ATVBAHA.117.309137
Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X et al.(2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun vol. 8, 14977-14977.
10.1038/ncomms14977
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33363
MUNROE PB, Caulfield M, Stirrups K, van den Berg M, Warren H, Cabrera CP(2017). Discovery of novel heart rate-associated loci using the exome chip. Human Molecular Genetics
10.1093/hmg/ddx113
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22369
Rastogi D, Jung M, Strizich G, Shaw PA, Davis SM, Klein OL, Penedo FJ, Ries AL et al.(2017). Association of systemic inflammation, adiposity, and metabolic dysregulation with asthma burden among Hispanic adults. Respiratory Medicine vol. 125, 72-81.
10.1016/j.rmed.2017.03.003
Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EGY et al.(2017). Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. Nature Communications vol. 8,
10.1038/ncomms14694
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22359
Webb TR, Erdmann J, Stirrups KE, Stitziel NO, Masca NGD, Jansen H, Kanoni S, Nelson CP et al.(2017). Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. J Am Coll Cardiol vol. 69, (7) 823-836.
10.1016/j.jacc.2016.11.056
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19641
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature vol. 542, (7640) 186-190.
10.1038/nature21039
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23049
Avilés-Santa ML, Pérez CM, Schneiderman N, Savage PJ, Kaplan RC, Teng Y, Suárez EL, Cai J et al.(2017). Detecting prediabetes among Hispanics/Latinos from diverse heritage groups: Does the test matter? Findings from the Hispanic Community Health Study/Study of Latinos. Preventive Medicine vol. 95, 110-118.
10.1016/j.ypmed.2016.12.009
Hedman ÅK, Mendelson MM, Marioni RE, Gustafsson S, Joehanes R, Irvin MR, Zhi D, Sandling JK et al.(2017). Epigenetic Patterns in Blood Associated with Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results from Genome-Wide Association Studies. Circulation: Cardiovascular Genetics vol. 10, (1)
10.1161/CIRCGENETICS.116.001487
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23424
Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW et al.(2017). Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Molecular Psychiatry vol. 22, (2) 192-201.
10.1038/mp.2016.71
Jansen IE, Ye H, Heetveld S, Lechler MC, Michels H, Seinstra RI, Lubbe SJ, Drouet V et al.(2017). Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Genome Biol vol. 18, (1) 22-22.
10.1186/s13059-017-1147-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34323
Jones GT, Tromp G, Kuivaniemi H, Gretarsdottir S, Baas AF, Giusti B, Strauss E, Van'T Hof FNG et al.(2017). Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. Circulation Research vol. 120, (2) 341-353.
10.1161/CIRCRESAHA.116.308765
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23425
Butterfield TR, Hanna DB, Kaplan RC, Kizer JR, Durkin HG, Young MA, Nowicki MJ, Tien PC et al.(2017). Increased glucose transporter-1 expression on intermediate monocytes from HIV-infected women with subclinical cardiovascular disease. AIDS vol. 31, (2) 199-205.
10.1097/QAD.0000000000001320
Carr DF, Bourgeois S, Chaponda M, Takeshita LY, Morris AP, Castro EMC, Alfirevic A, Jones AR et al.(2017). Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population. Journal of Antimicrobial Chemotherapy
10.1093/jac/dkw545
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19421
Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS et al.(2017). Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature vol. 541, (7635) 81-86.
10.1038/nature20784
Hanna DB, Lin J, Post WS, Hodis HN, Xue X, Anastos K, Cohen MH, Gange SJ et al.(2017). Association of macrophage inflammation biomarkers with progression of subclinical carotid artery atherosclerosis in HIV-infected women and men. Journal of Infectious Diseases vol. 215, (9) 1352-1361.
10.1093/infdis/jix082
Tarraf W, Rodríguez CJ, Daviglus ML, Lamar M, Schneiderman N, Gallo L, Talavera GA, Kaplan RC et al.(2017). Blood Pressure and Hispanic/Latino Cognitive Function: Hispanic Community Health Study/Study of Latinos Results. Journal of Alzheimer's Disease vol. 59, (1) 31-42.
10.3233/JAD-170017
Kaplan RC, Strizich G, Aneke-Nash C, Dominguez-Islas C, Bužková P, Strickler H, Rohan T, Pollak M et al.(2017). Insulinlike growth factor binding protein-1 and ghrelin predict health outcomes among older adults: Cardiovascular health study cohort. Journal of Clinical Endocrinology and Metabolism vol. 102, (1) 267-278.
10.1210/jc.2016-2779
Lotta LA, Gulati P, Day FR, Payne F, Ongen H, Van De Bunt M, Gaulton KJ, Eicher JD et al.(2017). Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nature Genetics vol. 49, (1) 17-26.
10.1038/ng.3714
Varga TV, Kurbasic A, Aine M, Eriksson P, Ali A, Hindy G, Gustafsson S, Luan J et al.(2017). Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults. International Journal of Epidemiology vol. 46, (4) 1211-1222.
10.1093/ije/dyw245
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51483
Qi Q, Hua S, Perreira KM, Cai J, Van Horn L, Schneiderman N, Thyagarajan B, Delamater AM et al.(2017). Sex differences in associations of adiposity measures and insulin resistance in US Hispanic/Latino youth: The Hispanic community children's health study/study of latino youth (SOL youth). Journal of Clinical Endocrinology and Metabolism vol. 102, (1) 185-194.
10.1210/jc.2016-2279
Aneke-Nash CS, Xue X, Qi Q, Biggs ML, Cappola A, Kuller L, Pollak M, Psaty BM et al.(2017). The association between IGF-I and IGFBP-3 and incident diabetes in an older population of men and women in the cardiovascular health study. Journal of Clinical Endocrinology and Metabolism vol. 102, (12) 4541-4547.
10.1210/jc.2017-01273
Roos L, Sandling JK, Bell CG, Glass D, Mangino M, Spector TD, Deloukas P, Bataille V et al.(2016). Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma. Journal of Investigative Dermatology vol. 137, (4) 910-920.
10.1016/j.jid.2016.11.029
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61076
Gregson JM, Freitag DF, Surendran P, Stitziel NO, Chowdhury R, Burgess S, Kaptoge S, Gao P et al.(2016). Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles. Eur J Prev Cardiol
10.1177/2047487316682186
https://qmro.qmul.ac.uk/xmlui/handle/123456789/21440
Kuniholm MH, Jung M, Del Amo J, Talavera GA, Thyagarajan B, Hershow RC, Damas OM, Kaplan RC(2016). Awareness of Hepatitis C Virus Seropositivity and Chronic Infection in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Journal of Immigrant and Minority Health vol. 18, (6) 1257-1265.
10.1007/s10903-016-0350-1
Barban N, Jansen R, De Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF et al.(2016). Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nature Genetics vol. 48, (12) 1462-1472.
10.1038/ng.3698
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28806
Salazar CR, Strizich G, Seeman TE, Isasi CR, Gallo LC, Avilés-Santa LM, Cai J, Penedo FJ et al.(2016). Nativity differences in allostatic load by age, sex, and Hispanic background from the Hispanic Community Health Study/Study of Latinos. SSM - Population Health vol. 2, 416-424.
10.1016/j.ssmph.2016.05.003
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G et al.(2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications vol. 7, 13357-13357.
10.1038/ncomms13357
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19341
Qi Q, Gogarten SM, Emery LS, Louie T, Stilp A, Cai J, Schneiderman N, Avilés-Santa ML et al.(2016). Genetic variation near IRS1 is associated with adiposity and a favorable metabolic profile in U.S. Hispanics/Latinos. Obesity vol. 24, (11) 2407-2413.
10.1002/oby.21624
Klein OL, Aviles-Santa L, Cai J, Collard HR, Kanaya AM, Kaplan RC, Kinney GL, Mendes E et al.(2016). Hispanics/Latinos with type 2 diabetes have functional and symptomatic pulmonary impairment mirroring kidney microangiopathy: Findings from the hispanic community health study/study of Latinos (HCHS/SOL). Diabetes Care vol. 39, (11) 2051-2057.
10.2337/dc16-1170
Hanna DB, Ramaswamy C, Kaplan RC, Kizer JR, Anastos K, Daskalakis D, Zimmerman R, Braunstein SL(2016). Trends in Cardiovascular Disease Mortality among Persons with HIV in New York City, 2001-2012. Clinical Infectious Diseases vol. 63, (8) 1122-1129.
10.1093/cid/ciw470
Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC et al.(2016). No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Sci Rep vol. 6, 35278-35278.
10.1038/srep35278
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18137
Lotta LA, Sharp SJ, Burgess S, Perry JRB, Stewart ID, Willems SM, Luan J, Ardanaz E et al.(2016). Association between low-density lipoprotein cholesterol-lowering genetic variants and risk of type 2 diabetes: A meta-analysis. JAMA - Journal of the American Medical Association vol. 316, (13) 1383-1391.
10.1001/jama.2016.14568
Demmer RT, Allison MA, Cai J, Kaplan RC, Desai AA, Hurwitz BE, Newman JC, Shah SJ et al.(2016). Association of Impaired Glucose Regulation and Insulin Resistance with Cardiac Structure and Function: Results from ECHO-SOL (Echocardiographic Study of Latinos). Circulation: Cardiovascular Imaging vol. 9, (10)
10.1161/CIRCIMAGING.116.005032
Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M et al.(2016). Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell vol. 15, (5) 811-824.
10.1111/acel.12490
Liu C, Kraja AT, Smith JA, Brody JA, Franceschini N, Bis JC, Rice K, Morrison AC et al.(2016). Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nature Genetics vol. 48, (10) 1162-1170.
10.1038/ng.3660
Franceschini N, Deng Y, Flessner MF, Eckfeldt JH, Kramer HJ, Lash JP, Lee DJ, Melamed ML et al.(2016). Smoking patterns and chronic kidney disease in US Hispanics: Hispanic Community Health Study/Study of Latinos. Nephrology Dialysis Transplantation vol. 31, (10) 1670-1676.
10.1093/ndt/gfw210
Hanna DB, Jung M, Xue X, Anastos K, Cocohoba JM, Cohen MH, Golub ET, Hessol NA et al.(2016). Trends in Nonlipid Cardiovascular Disease Risk Factor Management in the Women's Interagency HIV Study and Association with Adherence to Antiretroviral Therapy. AIDS Patient Care and STDs vol. 30, (10) 445-454.
10.1089/apc.2016.0143
MUNROE PB(2016). Trans-ancestry meta-analyses identify novel rare and common variants associated with blood pressure and hypertension. Nature Genetics
10.1038/ng.3654
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13707
MUNROE PB(2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics
10.1038/ng.3667
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15563
Willems SM, Cornes BK, Brody JA, Morrison AC, Lipovich L, Dauriz M, Chen Y, Liu CT et al.(2016). Association of the IGF1 gene with fasting insulin levels. European Journal of Human Genetics vol. 24, (9) 1337-1343.
10.1038/ejhg.2016.4
Daviglus ML, Pirzada A, Durazo-Arvizu R, Chen J, Allison M, Avilés-Santa L, Cai J, González HM et al.(2016). Prevalence of Low Cardiovascular Risk Profile Among Diverse Hispanic/Latino Adults in the United States by Age, Sex, and Level of Acculturation: The Hispanic Community Health Study/Study of Latinos. Journal of the American Heart Association vol. 5, (8)
10.1161/JAHA.116.003929
Kanoni S, Masca NGD, Stirrups KE, Varga TV, Warren HR, Scott RA, Southam L, Zhang W et al.(2016). Analysis with the exome array identifies multiple new independent variants in lipid loci. Human Molecular Genetics vol. 25, (18) ddw227-ddw227.
10.1093/hmg/ddw227
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14812
Hanna DB, Guo M, B¿žková P, Miller TL, Post WS, Stein JH, Currier JS, Kronmal RA et al.(2016). HIV Infection and Carotid Artery Intima-media Thickness: Pooled Analyses Across 5 Cohorts of the NHLBI HIV-CVD Collaborative. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America vol. 63, (2) 249-256.
10.1093/cid/ciw261
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P et al.(2016). The genetic architecture of type 2 diabetes. Nature vol. 536, (7614) 41-47.
10.1038/nature18642
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23544
Strizich G, Kaplan RC, González HM, Daviglus ML, Giachello AL, Teng Y, Lipton RB, Grober E(2016). Glycemic control, cognitive function, and family support among middle-aged and older Hispanics with diabetes: The Hispanic Community Health Study/Study of Latinos. Diabetes Research and Clinical Practice vol. 117, 64-73.
10.1016/j.diabres.2016.04.052
Wong WW, Strizich G, Heo M, Heymsfield SB, Himes JH, Rock CL, Gellman MD, Siega-Riz AM et al.(2016). Relationship between body fat and BMI in a US hispanic population-based cohort study: Results from HCHS/SOL. Obesity vol. 24, (7) 1561-1571.
10.1002/oby.21495
Viatte S, Massey J, Bowes J, Duffus K, Eyre S, Barton A, Worthington J, Loughlin J et al.(2016). Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis. Arthritis and Rheumatology vol. 68, (7) 1603-1613.
10.1002/art.39619
van't Hof FNG, Ruigrok YM, Lee CH, Ripke S, Anderson G, de Andrade M, Baas AF, Blankensteijn JD et al.(2016). Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms. Journal of the American Heart Association vol. 5, (7)
10.1161/JAHA.115.002603
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T et al.(2016). Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet vol. 12, (6) e1006166-e1006166.
10.1371/journal.pgen.1006166
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35005
Eicher JD, Chami N, Kacprowski T, Nomura A, Chen M-H, Yanek LR, Tajuddin SM, Schick UM et al.(2016). Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. American Journal of Human Genetics vol. 99, (1) 40-55.
10.1016/j.ajhg.2016.05.005
Busby GBJ, Band G, Le QS, Jallow M, Bougama E, Mangano VD, Amenga-Etego LN, Enimil A et al.(2016). Admixture into and within sub-Saharan Africa. eLife vol. 5, (JUN2016)
10.7554/eLife.15266.001
Busby GB, Band G, Si Le Q, Jallow M, Bougama E, Mangano VD, Amenga-Etego LN, Enimil A et al.(2016). Admixture into and within sub-Saharan Africa. Elife vol. 5,
10.7554/eLife.15266
Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stancakova A et al.(2016). A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Science Translational Medicine vol. 8, (341) 341ra76-341ra76.
10.1126/scitranslmed.aad3744
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13116
Golbus JR, Stitziel NO, Zhao W, Xue C, Farrall M, Mcpherson R, Erdmann J, Deloukas P et al.(2016). Common and rare genetic variation in CCR2, CCR5, or CX3CR1 and risk of atherosclerotic coronary heart disease and glucometabolic traits. Circulation: Cardiovascular Genetics vol. 9, (3) 250-258.
10.1161/CIRCGENETICS.115.001374
Sanders JL, Arnold AM, Hirsch CH, Thielke SM, Kim D, Mukamal KJ, Kizer JR, Ix JH et al.(2016). Effects of Disease Burden and Functional Adaptation on Morbidity and Mortality on Older Adults. Journal of the American Geriatrics Society vol. 64, (6) 1242-1249.
10.1111/jgs.14163
Jackson VE, Ntalla I, Sayers I, Morris R, Whincup P, Casas JP, Amuzu A, Choi M et al.(2016). Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12. Thorax vol. 71, (6) 501-509.
10.1136/thoraxjnl-2015-207876
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14815
Rautanen A, Pirinen M, Mills TC, Rockett KA, Strange A, Ndungu AW, Naranbhai V, Gilchrist JJ et al.(2016). Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children. The American Journal of Human Genetics vol. 98, (6) 1092-1100.
10.1016/j.ajhg.2016.03.025
Shah N, Hanna DB, Teng Y, Sotres-Alvarez D, Hall M, Loredo JS, Zee P, Kim M et al.(2016). Sex-Specific Prediction Models for Sleep Apnea from the Hispanic Community Health Study/Study of Latinos This article has been presented in abstract form (Shah NA, Hanna DB, Teng Y, et al. Epidemiol Genet Sleep Disordered Breathing. 2014: A5334). Chest vol. 149, (6) 1409-1418.
10.1016/j.chest.2016.01.013
Greenblatt AP, Salazar CR, Northridge ME, Kaplan RC, Taylor GW, Finlayson TL, Qi Q, Badner V(2016). Association of diabetes with tooth loss in Hispanic/Latino adults: Findings from the hispanic community health Study/ Study of latinos. BMJ Open Diabetes Research and Care vol. 4, (1)
10.1136/bmjdrc-2016-000211
Stitziel NO, Stirrups KE, Masca NGD, Erdmann J, Ferrario PG, Koenig IR, Weeke PE, Webb TR et al.(2016). Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease (vol 374, pg 1134, 2016). NEW ENGLAND JOURNAL OF MEDICINE vol. 374, (19) 1898-1898.
Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen G-B et al.(2016). Genome-wide association study identifies 74 loci associated with educational attainment. Nature vol. 533, (7604) 539-542.
10.1038/nature17671
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23589
Bodea CA, Neale BM, Ripke S, Daly MJ, Devlin B, Roeder K(2016). A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies. American Journal of Human Genetics vol. 98, (5) 857-868.
10.1016/j.ajhg.2016.02.025
Golbus JR, Stitziel N, Samani N, Erdmann J, Schunkert H, Deloukas P, Saleheen D, Farrall M et al. (2016). COMMON OR RARE GENETIC VARIATION IN THE CHEMOKINE RECEPTORS CCR2, CCR5, AND CX3CR1 DOES NOT RELATE TO CORONARY HEART DISEASE OR MYOCARDIAL INFARCTION IN HUMANS. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 67, 1891-1891.
10.1016/S0735-1097(16)31892-7
Mehta H, Armstrong A, Swett K, Shah SJ, Allison MA, Hurwitz B, Bangdiwala S, Dadhania R et al.(2016). Burden of systolic and diastolic left ventricular dysfunction among hispanics in the United States. Circulation: Heart Failure vol. 9, (4)
10.1161/CIRCHEARTFAILURE.115.002733
Xiang L, Wu H, Pan A, Patel B, Xiang G, Qi L, Kaplan RC, Hu F et al.(2016). FTO genotype and weight loss in diet and lifestyle interventions: A systematic review and meta-analysis. American Journal of Clinical Nutrition vol. 103, (4) 1162-1170.
10.3945/ajcn.115.123448
Wang X, Jung M, Mossavar-Rahmani Y, Sotres-Alvarez D, Espinoza Giacinto RA, Pirzada A, Reina SA, Casagrande SS et al.(2016). Macronutrient intake, diagnosis status, and glycemic control among US Hispanics/Latinos with diabetes. Journal of Clinical Endocrinology and Metabolism vol. 101, (4) 1856-1864.
10.1210/jc.2015-3237
Stitziel NO, Stirrups KE, Masca NGD, Erdmann J, Ferrario PG, König IR, Weeke PE, Webb TR et al.(2016). Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease. New England Journal of Medicine vol. 374, (12) 1134-1144.
10.1056/NEJMoa1507652
Zanoni P, Khetarpal SA, Larach DB, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A et al.(2016). Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science vol. 351, (6278) 1166-1171.
10.1126/science.aad3517
Lesage S, Drouet V, Majounie E, Deramecourt V, Jacoupy M, Nicolas A, Cormier-Dequaire F, Hassoun SM et al.(2016). Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy. Am J Hum Genet vol. 98, (3) 500-513.
10.1016/j.ajhg.2016.01.014
Marouli E, Kanoni S, Dimitriou M, Kolovou G, Deloukas P, Dedoussis G(2016). Lifestyle may modify the glucose-raising effect of genetic loci. A study in the Greek population. Nutrition, Metabolism and Cardiovascular Diseases vol. 26, (3) 201-206.
10.1016/j.numecd.2015.10.003
Brutsaert EF, Shitole S, Biggs ML, Mukamal KJ, DeBoer IH, Thacker EL, Barzilay JI, Djoussé L et al.(2016). Relations of Postload and Fasting Glucose With Incident Cardiovascular Disease and Mortality Late in Life: The Cardiovascular Health Study. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 71, (3) 370-377.
10.1093/gerona/glv106
Harris SE, Malik R, Marioni R, Campbell A, Seshadri S, Worrall BB, Sudlow CLM, Hayward C et al.(2016). Polygenic risk of ischemic stroke is associated with cognitive ability. Neurology vol. 86, (7) 611-618.
10.1212/WNL.0000000000002306
Barr RG, Avilés-Santa L, Davis SM, Aldrich TK, Gonzalez F, Henderson AG, Kaplan RC, La Vange L et al.(2016). Pulmonary disease and age at immigration among hispanics: Results from the hispanic community health study/study of latinos. American Journal of Respiratory and Critical Care Medicine vol. 193, (4) 386-395.
10.1164/rccm.201506-1211OC
Aneke-Nash CS, Dominguez-Islas C, B¿žková P, Qi Q, Xue X, Pollak M, Strickler HD, Kaplan RC(2016). Agreement between circulating IGF-I, IGFBP-1 and IGFBP-3 levels measured by current assays versus unavailable assays previously used in epidemiological studies. Growth Hormone and IGF Research vol. 26, 11-16.
10.1016/j.ghir.2015.12.007
Isasi CR, Jung M, Parrinello CM, Kaplan RC, Kim R, Crespo NC, Gonzalez P, Gouskova NA et al.(2016). Association of childhood economic hardship with adult height and adult adiposity among hispanics/latinos. The HCHS/SOL socio-cultural ancillary study. PLoS ONE vol. 11, (2)
10.1371/journal.pone.0149923
Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z et al.(2016). New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications vol. 7,
10.1038/ncomms10495
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18699
Kaplan RC, Hanna DB, Kizer JR(2016). Recent Insights Into Cardiovascular Disease (CVD) Risk Among HIV-Infected Adults. Current HIV/AIDS Reports vol. 13, (1) 44-52.
10.1007/s11904-016-0301-4
Jung M, Kuniholm MH, Ho GYF, Cotler S, Strickler HD, Thyagarajan B, Youngblood M, Kaplan RC et al.(2016). The distribution of hepatitis B virus exposure and infection in a population-based sample of U.S. Hispanic adults. Hepatology vol. 63, (2) 445-452.
10.1002/hep.28328
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A et al.(2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications vol. 7,
10.1038/ncomms10023
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12758
Roos L, van Dongen J, Bell CG, Burri A, Deloukas P, Boomsma DI, Spector TD, Bell JT(2016). Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs. Clinical Epigenetics vol. 8, (1) 1-16.
10.1186/s13148-016-0172-y
Conomos MP, Laurie CA, Stilp AM, Gogarten SM, McHugh CP, Nelson SC, Sofer T, Fernández-Rhodes L et al.(2016). Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos. American Journal of Human Genetics vol. 98, (1) 165-184.
10.1016/j.ajhg.2015.12.001
Bourgeois S, Jorgensen A, Zhang EJ, Hanson A, Gillman MS, Bumpstead S, Toh CH, Williamson P et al.(2016). A multi-factorial analysis of response to warfarin in a UK prospective cohort. Genome Medicine vol. 8, (1)
10.1186/s13073-015-0255-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11191
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS et al.(2016). A novel Alzheimer disease locus located near the gene encoding tau protein. Molecular Psychiatry vol. 21, (1) 108-117.
10.1038/mp.2015.23
Ahmad S, Zhao W, Renström F, Rasheed A, Zaidi M, Samuel M, Shah N, Mallick NH et al.(2016). A novel interaction between the FLJ33534 locus and smoking in obesity: A genome-wide study of 14 131 Pakistani adults. International Journal of Obesity vol. 40, (1) 186-190.
10.1038/ijo.2015.152
González HM, Tarraf W, Rodríguez CJ, Gallo LC, Sacco RL, Talavera GA, Heiss G, Kizer JR et al.(2016). Cardiovascular health among diverse Hispanics/Latinos: Hispanic Community Health Study/Study of Latinos (HCHS/SOL) results. American Heart Journal vol. 176, 134-144.
10.1016/j.ahj.2016.02.008
Mattei J, Sotres-Alvarez D, Daviglus ML, Gallo LC, Gellman M, Hu FB, Tucker KL, Willett WC et al.(2016). Diet quality and its association with cardiometabolic risk factors vary by hispanic and latino ethnic background in the Hispanic community health study/study of Latinos. Journal of Nutrition vol. 146, (10) 2035-2044.
10.3945/jn.116.231209
Wang X, Strizich G, Hu Y, Wang T, Kaplan RC, Qi Q(2016). Genetic markers of type 2 diabetes: Progress in genome-wide association studies and clinical application for risk prediction. Journal of Diabetes vol. 8, (1) 24-35.
10.1111/1753-0407.12323
Love-Gregory L, Kraja AT, Allum F, Aslibekyan S, Hedman ÅK, Duan Y, Borecki IB, Arnett DK et al.(2016). Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36. Journal of Lipid Research vol. 57, (12) 2176-2184.
10.1194/jlr.P065250
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23504
Larissa Avilés-Santa M, Schneiderman N, Savage PJ, Kaplan RC, Teng Y, Pérez CM, Suárez EL, Cai J et al.(2016). Identifying probable diabetes mellitus among hispanics/latinos from four U.S. cities: Findings from the hispanic community health study/study of latinos. Endocrine Practice vol. 22, (10) 1151-1160.
10.4158/EP151144.OR
Browning SR, Grinde K, Plantinga A, Gogarten SM, Stilp AM, Kaplan RC, Avilés-Santa ML, Browning BL et al.(2016). Local ancestry inference in a large US-based Hispanic/Latino study: Hispanic community health study/study of Latinos (HCHS/SOL). G3: Genes, Genomes, Genetics vol. 6, (6) 1525-1534.
10.1534/g3.116.028779
Valdovinos C, Penedo FJ, Isasi CR, Jung M, Kaplan RC, Espinoza Giacinto R, Gonzalez P, Malcarne VL et al.(2016). Perceived discrimination and cancer screening behaviors in US Hispanics: the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study. Cancer Causes and Control vol. 27, (1) 27-37.
10.1007/s10552-015-0679-0
Chopra A, Jung M, Kaplan RC, Appel DW, Dinces EA, Dhar S, Zee PC, Gonzalez F et al.(2016). Sleep apnea is associated with hearing impairment: The Hispanic community health study/study of Latinos. Journal of Clinical Sleep Medicine vol. 12, (5) 719-726.
10.5664/jcsm.5804
Robinson PC, Leo PJ, Pointon JJ, Harris J, Cremin K, Bradbury LA, Donnelly P, Barroso I et al.(2016). The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis. Genes and Immunity vol. 17, (1) 46-51.
10.1038/gene.2015.49
Busche S, Shao X, Caron M, Kwan T, Allum F, Cheung WA, Ge B, Westfall S et al.(2015). Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation. Genome Biology vol. 16, (1)
10.1186/s13059-015-0856-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23530
Artigas MS, Wain LV, Miller S, Kheirallah AK, Huffman JE, Ntalla I, Shrine N, Obeidat M et al.(2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications vol. 6,
10.1038/ncomms9658
Escott-Price V, Sims R, Bannister C, Harold D, Vronskaya M, Majounie E, Badarinarayan N, GERAD/PERADES et al.(2015). Common polygenic variation enhances risk prediction for Alzheimer's disease. Brain vol. 138, (Pt 12) 3673-3684.
10.1093/brain/awv268
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A et al.(2015). Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics vol. 47, (12) 1415-1425.
10.1038/ng.3437
Merzel CR, Isasi CR, Strizich G, Castañeda SF, Gellman M, Maisonet Giachello AL, Lee DJ, Penedo FJ et al.(2015). Smoking cessation among U.S. Hispanic/Latino adults: Findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Preventive Medicine vol. 81, 412-419.
10.1016/j.ypmed.2015.10.006
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A et al.(2015). Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics
10.1038/ng.3437
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12100
Fretts AM, Follis JL, Nettleton JA, Lemaitre RN, Ngwa JS, Wojczynski MK, Kalafati IP, Varga TV et al.(2015). Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: A meta-analysis of 50,345 Caucasians. American Journal of Clinical Nutrition vol. 102, (5) 1266-1278.
10.3945/ajcn.114.101238
Strand LB, Carnethon M, Biggs ML, E LD, Kaplan RC, Siscovick DS, Robbins JA, Redline S et al.(2015). Sleep disturbances and glucose metabolism in older adults: The cardiovascular health study. Diabetes Care vol. 38, (11) 2050-2058.
10.2337/dc15-0137
Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, NKelly T, Saleheen D et al.(2015). Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature Genetics vol. 47, (11) 1282-1293.
10.1038/ng.3405
Qi Q, Strizich G, Merchant G, Sotres-Alvarez D, Buelna C, Castañeda SF, Gallo LC, Cai J et al.(2015). Objectively measured sedentary time and cardiometabolic biomarkers in US Hispanic/Latino adults: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Circulation vol. 132, (16) 1560-1569.
10.1161/CIRCULATIONAHA.115.016938
Evans DS, Cailotto F, Parimi N, Valdes AM, Castaño-Betancourt MC, Liu Y, Kaplan RC, Bidlingmaier M et al.(2015). Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis. Annals of the Rheumatic Diseases vol. 74, (10) 1861-1867.
10.1136/annrheumdis-2013-205020
Uyoga S, Ndila CM, Macharia AW, Nyutu G, Shah S, Peshu N, Clarke GM, Kwiatkowski DP et al.(2015). Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children in Kenya: a case-control and a cohort study. Lancet Haematol vol. 2, (10) e437-e444.
10.1016/S2352-3026(15)00152-0
Wain LV, Shrine N, Miller S, Jackson VE, Ntalla I, Artigas MS, Billington CK, Kheirallah AK et al.(2015). Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank. The Lancet Respiratory Medicine vol. 3, (10) 769-781.
10.1016/S2213-2600(15)00283-0
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T et al.(2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS genetics vol. 11, (10)
10.1371/journal.pgen.1005378
Qi Q, Strizich G, Hanna DB, Giacinto RE, Castañeda SF, Sotres-Alvarez D, Pirzada A, Llabre MM et al.(2015). Comparing measures of overall and central obesity in relation to cardiometabolic risk factors among US Hispanic/Latino adults. Obesity vol. 23, (9) 1920-1928.
10.1002/oby.21176
Allison MA, Gonzalez F, Raij L, Kaplan R, Ostfeld RJ, Pattany MS, Heiss G, Criqui MH(2015). Cuban Americans have the highest rates of peripheral arterial disease in diverse Hispanic/Latino communities. Journal of Vascular Surgery vol. 62, (3) 665-672.
10.1016/j.jvs.2015.03.065
Hanna DB, Post WS, Deal JA, Hodis HN, Jacobson LP, Mack WJ, Anastos K, Gange SJ et al.(2015). HIV Infection Is Associated with Progression of Subclinical Carotid Atherosclerosis. Clinical Infectious Diseases vol. 61, (4) 640-650.
10.1093/cid/civ325
Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE et al.(2015). Rare coding variants and X-linked loci associated with age at menarche. Nature Communications vol. 6,
10.1038/ncomms8756
Navas-Nacher EL, Kelley MA, Birnbaum-Weitzman O, Gonzalez P, Ghiachello AL, Kaplan RC, Lee DJ, Bandiera FC et al.(2015). Association between exposure to household cigarette smoking behavior and cigarette smoking in Hispanic adults: Findings from the Hispanic Community Health Study/Study of Latinos. Preventive Medicine vol. 77, 35-40.
10.1016/j.ypmed.2015.04.011
Demerath EW, Guan W, Grove ML, Aslibekyan S, Mendelson M, Zhou YH, Hedman ÅK, Sandling JK et al.(2015). Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. Human molecular genetics vol. 24, (15) 4464-4479.
10.1093/hmg/ddv161
Dashti HS, Follis JL, Smith CE, Tanaka T, Garaulet M, Gottlieb DJ, Hruby A, Jacques PF et al.(2015). Gene-environment interactions of circadian-related genes for cardiometabolic traits. Diabetes Care vol. 38, (8) 1456-1466.
10.2337/dc14-2709
Allum F, Shao X, Guénard F, Simon MM, Busche S, Caron M, Lambourne J, Lessard J et al.(2015). Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants (Nature Communications (2015) 6 (7211) DOI: 10.1038/ncomms8211 (2015)). Nature Communications vol. 6,
10.1038/ncomms9016
Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C et al.(2015). Directional dominance on stature and cognition in diverse human populations. Nature vol. 523, (7561) 459-462.
10.1038/nature14618
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12751
Qi Q, Downer MK, Kilpelainen TO, Taal HR, Barton SJ, Ntalla I, Standl M, Boraska V et al.(2015). Dietary Intake, FTO genetic variants, and adiposity: A combined analysis of over 16,000 children and adolescents. Diabetes vol. 64, (7) 2467-2476.
10.2337/db14-1629
Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, De Geus EJC, Hemani G et al.(2015). The association between lower educational attainment and depression owing to shared genetic effects? Results in ∼25 000 subjects. Molecular Psychiatry vol. 20, (6) 735-743.
10.1038/mp.2015.50
Rodriguez CJ, Cai J, Swett K, González HM, Talavera GA, Wruck LM, Wassertheil-Smoller S, Lloyd-Jones D et al.(2015). High Cholesterol Awareness, Treatment, and Control Among Hispanic/Latinos: Results From the Hispanic Community Health Study/Study of Latinos. Journal of the American Heart Association vol. 4, (7)
10.1161/JAHA.115.001867
Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JRB, Boehme KL et al.(2015). Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. PLoS Medicine vol. 12, (6)
10.1371/journal.pmed.1001841
Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N et al.(2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry vol. 20, (5) 647-656.
10.1038/mp.2014.107
Allum F, Shao X, Guénard F, Simon MM, Busche S, Caron M, Lambourne J, Lessard J et al.(2015). Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants. Nature Communications vol. 6,
10.1038/ncomms8211
Hosp F, Vossfeldt H, Heinig M, Vasiljevic D, Arumughan A, Wyler E, Genetic and Environmental Risk for Alzheimer¿s Disease GERAD1 Consortium, Landthaler M et al.(2015). Quantitative interaction proteomics of neurodegenerative disease proteins. Cell Rep vol. 11, (7) 1134-1146.
10.1016/j.celrep.2015.04.030
Coffee and Caffeine Genetics Consortium, Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL et al.(2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Mol Psychiatry vol. 20, (5) 647-656.
10.1038/mp.2014.107
Lindner C, Thiagarajah S, Wilkinson JM, Panoutsopoulou K, Day-Williams AG, arcOGEN Consortium, Cootes TF, Wallis GA(2015). Investigation of association between hip osteoarthritis susceptibility loci and radiographic proximal femur shape. Arthritis Rheumatol vol. 67, (8) 2076-2084.
10.1002/art.39186
Aung T, Ozaki M, Mizoguchi T, Allingham RR, Li Z, Haripriya A, Nakano S, Uebe S et al.(2015). A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. Nature Genetics vol. 47, (4) 387-392.
10.1038/ng.3226
Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK et al.(2015). Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nature Genetics vol. 47, (4) 381-386.
10.1038/ng.3245
Nettleton JA, Follis JL, Ngwa JS, Smith CE, Ahmad S, Tanaka T, Wojczynski MK, Voortman T et al.(2015). Gene × dietary pattern interactions in obesity: Analysis of up to 68 317 adults of European ancestry. Human Molecular Genetics vol. 24, (16) 4728-4738.
10.1093/hmg/ddv186
Nelson CP, Hamby SE, Saleheen D, Hopewell JC, Zeng L, Assimes TL, Kanoni S, Willenborg C et al.(2015). Genetically determined height and coronary artery disease. New England Journal of Medicine vol. 372, (17) 1608-1618.
10.1056/NEJMoa1404881
Pfeiffer L, Wahl S, Pilling LC, Reischl E, Sandling JK, Kunze S, Holdt LM, Kretschmer A et al.(2015). DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels. CIRCULATION-CARDIOVASCULAR GENETICS vol. 8, (2) 334-+.
10.1161/CIRCGENETICS.114.000804
Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C et al.(2015). A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension. PLoS Genetics vol. 11, (3)
10.1371/journal.pgen.1005035
Kaess BM, Preis SR, Lieb W, Beiser AS, Yang Q, Chen TC, Hengstenberg C, Erdmann J et al.(2015). Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community. J Am Heart Assoc vol. 4, (3)
10.1161/JAHA.114.001544
Nalls MA, Bras J, Hernandez DG, Keller MF, Majounie E, Renton AE, Saad M, Jansen I et al.(2015). NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases. Neurobiol Aging vol. 36, (3) 1605.e7-1605.12.
10.1016/j.neurobiolaging.2014.07.028
Rodriguez CJ, Dharod A, Allison MA, Shah SJ, Hurwitz B, Bangdiwala SI, Gonzalez F, Kitzman D et al.(2015). Rationale and design of the echocardiographic study of hispanics/latinos (ECHO-SOL). Ethnicity and Disease vol. 25, (2) 180-186.
Shah N, Allison M, Teng Y, Wassertheil-Smoller S, Sotres-Alvarez D, Ramos AR, Zee PC, Criqui MH et al.(2015). Sleep Apnea Is Independently Associated with Peripheral Arterial Disease in the Hispanic Community Health Study/Study of Latinos. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 35, (3) 710-715.
10.1161/ATVBAHA.114.304625
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S et al.(2015). Genetic studies of body mass index yield new insights for obesity biology. Nature vol. 518, (7538) 197-206.
10.1038/nature14177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6989
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH et al.(2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature vol. 518, (7538) 187-196.
10.1038/nature14132
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7200
Jung M, Parrinello CM, Xue X, Mack WJ, Anastos K, Lazar JM, Selzer RH, Shircore AM et al.(2015). Echolucency of the carotid artery intima-media complex and intima-media thickness have different cardiovascular risk factor relationships: the Women's Interagency HIV Study. Journal of the American Heart Association vol. 4, (2)
10.1161/JAHA.114.001405
Zhang W, Spector TD, Deloukas P, Bell JT, Engelhardt BE(2015). Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements. Genome Biology vol. 16, (1)
10.1186/s13059-015-0581-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18501
Pers TH, Karjalainen JM, Chan Y, Westra H-J, Wood AR, Yang J, Lui JC, Vedantam S et al.(2015). Biological interpretation of genome-wide association studies using predicted gene functions. Nat Commun vol. 6,
10.1038/ncomms6890
Nikpay M, Goel A, Won HH, Hall LM, Willenborg C, Kanoni S, Saleheen D, Kyriakou T et al.(2015). A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nature Genetics vol. 47, (10) 1121-1130.
10.1038/ng.3396
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14992
Goyal V, Miller K, Luttig CT, Hemrajani R (2015). Acute Lung Injury Due To Ceftaroline. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 191,
Aneke-Nash CS, Parrinello CM, Rajpathak SN, Rohan TE, Strotmeyer ES, Kritchevsky SB, Psaty BM, B¿žková P et al.(2015). Changes in insulin-like growth factor-I and its binding proteins are associated with diabetes mellitus in older adults. Journal of the American Geriatrics Society vol. 63, (5) 902-909.
10.1111/jgs.13390
Gunter MJ, Wang T, Cushman M, Xue X, Wassertheil-Smoller S, Strickler HD, Rohan TE, Manson JE et al.(2015). Circulating Adipokines and Inflammatory Markers and Postmenopausal Breast Cancer Risk. Journal of the National Cancer Institute vol. 107, (9)
10.1093/jnci/djv169
Pfeiffer L, Wahl S, Pilling LC, Reischl E, Sandling JK, Kunze S, Holdt LM, Kretschmer A et al.(2015). DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels. Circulation: Cardiovascular Genetics vol. 8, (2) 334-342.
10.1161/CIRCGENETICS.114.000804
Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA et al.(2015). GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 70, (1) 110-118.
10.1093/gerona/glu166
Dashti HS, Follis JL, Smith CE, Tanaka T, Cade BE, Gottlieb DJ, Hruby A, Jacques PF et al.(2015). Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants. American Journal of Clinical Nutrition vol. 101, (1) 135-143.
10.3945/ajcn.114.095026
Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF et al.(2015). Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications vol. 6,
10.1038/ncomms6897
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18365
Germain M, Chasman DI, De Haan H, Tang W, Lindström S, Weng LC, De Andrade M, De Visser MCH et al.(2015). Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism. American Journal of Human Genetics vol. 96, (4) 532-542.
10.1016/j.ajhg.2015.01.019
Parrinello CM, Isasi CR, Xue X, Bandiera FC, Cai J, Lee DJ, Navas-Nacher EL, Perreira KM et al.(2015). Risk of cigarette smoking initiation during adolescence among US-born and non - US-born Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. American Journal of Public Health vol. 105, (6) 1230-1236.
10.2105/AJPH.2014.302155
Kuniholm MH, Hanna DB, Landay AL, Kaplan RC, Ley K(2015). Soluble CD163 is associated with noninvasive measures of liver fibrosis in hepatitis C virus- and hepatitis C virus/human immunodeficiency virus-infected women. Hepatology vol. 61, (2) 734-735.
10.1002/hep.27303
Miller S, Wain L, Shrine N, Ntalla I, Cook J, Sayers I, Morris A, Zeggini E et al. (2015). The Uk Bileve Study: The First Genetic Study In Uk Biobank Identifies Novel Regions Associated With Airway Obstruction And Smoking Behaviour. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 191,
Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY et al.(2014). FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet vol. 23, (25) 6961-6972.
10.1093/hmg/ddu411
Evangelou E, Kerkhof HJ, Styrkarsdottir U, Ntzani EE, Bos SD, Esko T, Evans DS, Metrustry S et al.(2014). A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. Ann Rheum Dis vol. 73, (12) 2130-2136.
10.1136/annrheumdis-2012-203114
Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N et al.(2014). Inactivating mutations in NPC1L1 and protection from coronary heart disease. New England Journal of Medicine vol. 371, (22) 2072-2082.
10.1056/NEJMoa1405386
Huertas-Vazquez A, Nelson CP, Sinsheimer JS, Reinier K, Uy-Evanado A, Teodorescu C, Ayala J, Gunson K et al. (2014). Toward Development of a Genetic Risk Score for Sudden Cardiac Death. CIRCULATION. vol. 130,
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K et al.(2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics vol. 46, (11) 1173-1186.
10.1038/ng.3097
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K et al.(2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet vol. 46, (11) 1173-1186.
10.1038/ng.3097
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6379
Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D et al.(2014). Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun vol. 5,
10.1038/ncomms5926
Horvath S, Erhart W, Brosch M, Ammerpohl O, von Schönfels W, Ahrens M, Heits N, Bell JT et al.(2014). Obesity accelerates epigenetic aging of human liver. Proc Natl Acad Sci U S A vol. 111, (43) 15538-15543.
10.1073/pnas.1412759111
Adoue V, Schiavi A, Light N, Almlöf JC, Lundmark P, Ge B, Kwan T, Caron M et al.(2014). Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs. Mol Syst Biol vol. 10,
10.15252/msb.20145114
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6540
Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N et al.(2014). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry
10.1038/mp.2014.107
Perry JRB, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI et al.(2014). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature vol. 514, (7520) 92-97.
10.1038/nature13545
McArdle PF, Kittner SJ, Ay H, Brown RD, Meschia JF, Rundek T, Wassertheil-Smoller S, Woo D et al.(2014). Agreement between TOAST and CCS ischemic stroke classification: The NINDS SiGN Study. Neurology vol. 83, (18) 1653-1660.
10.1212/WNL.0000000000000942
Wassertheil-Smoller S, Mcginn A, Allison M, Ca T, Curb D, Eaton C, Hendrix S, Kaplan R et al.(2014). Improvement in stroke risk prediction: Role of C-reactive protein and lipoprotein-associated phospholipase A<inf>2</inf> in the women's health initiative. International Journal of Stroke vol. 9, (7) 902-909.
10.1111/j.1747-4949.2012.00860.x
Chen G-B, Lee SH, Brion M-JA, Montgomery GW, Wray NR, Radford-Smith GL, Visscher PM, International IBD Genetics Consortium(2014). Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data. Hum Mol Genet vol. 23, (17) 4710-4720.
10.1093/hmg/ddu174
Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M et al.(2014). Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis. PLoS Medicine vol. 11, (9)
10.1371/journal.pmed.1001713
Liu C-T, Buchkovich ML, Winkler TW, Heid IM, African Ancestry Anthropometry Genetics Consortium, GIANT Consortium, Borecki IB, Fox CS et al.(2014). Multi-ethnic fine-mapping of 14 central adiposity loci. Hum Mol Genet vol. 23, (17) 4738-4744.
10.1093/hmg/ddu183
Brænne I, Reiz B, Medack A, Kleinecke M, Fischer M, Tuna S, Hengstenberg C, Deloukas P et al.(2014). Whole-exome sequencing in an extended family with myocardial infarction unmasks familial hypercholesterolemia. BMC Cardiovasc Disord vol. 14,
10.1186/1471-2261-14-108
Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K et al.(2014). Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nature Communications vol. 5, Article 5068,
10.1038/ncomms6068
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6802
Ng MCY, Shriner D, Chen BH, Li J, Chen WM, Guo X, Liu J, Bielinski SJ et al.(2014). Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes. PLoS Genetics vol. 10, (8)
10.1371/journal.pgen.1004517
Rosenberg MA, Kaplan RC, Siscovick DS, Psaty BM, Heckbert SR, Newton-Cheh C, Mukamal KJ(2014). Genetic variants related to height and risk of atrial fibrillation. American Journal of Epidemiology vol. 180, (2) 215-222.
10.1093/aje/kwu126
Davis OSP, Band G, Pirinen M, Haworth CMA, Meaburn EL, Kovas Y, Harlaar N, Docherty SJ et al.(2014). The correlation between reading and mathematics ability at age twelve has a substantial genetic component. Nat Commun vol. 5,
10.1038/ncomms5204
TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung, and Blood Institute, Crosby J, Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y et al.(2014). Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med vol. 371, (1) 22-31.
10.1056/NEJMoa1307095
Bryois J, Buil A, Evans DM, Kemp JP, Montgomery SB, Conrad DF, Ho KM, Ring S et al.(2014). Cis and trans effects of human genomic variants on gene expression. PLoS Genet vol. 10, (7)
10.1371/journal.pgen.1004461
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6742
Nicodemus KK, Hargreaves A, Morris D, Anney R, Gill M, Corvin A, Donohoe G, Ripke S et al.(2014). Variability inworking memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway. JAMA Psychiatry vol. 71, (7) 778-785.
10.1001/jamapsychiatry.2014.528
Dick KJ, Nelson CP, Tsaprouni L, Sandling JK, Aïssi D, Wahl S, Meduri E, Morange P-E et al.(2014). DNA methylation and body-mass index: a genome-wide analysis. Lancet vol. 383, (9933) 1990-1998.
10.1016/S0140-6736(13)62674-4
Murphy TM, Mill J(2014). Epigenetics in health and disease: heralding the EWAS era. The Lancet vol. 383, (9933) 1952-1954.
10.1016/s0140-6736(14)60269-5
Dong J, Gao J, Nalls M, Gao X, Huang X, Han J, Singleton AB, Chen H et al.(2014). Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease. Neurobiol Aging vol. 35, (6) 1512.e5-1512.e10.
10.1016/j.neurobiolaging.2013.12.020
Kuniholm MH, Jung M, Everhart JE, Cotler S, Heiss G, McQuillan G, Kim RS, Strickler HD et al.(2014). Prevalence of hepatitis c virus infection in US hispanic/Latino adults: Results from the NHANES 2007-2010 and HCHS/SOL studies. Journal of Infectious Diseases vol. 209, (10) 1585-1590.
10.1093/infdis/jit672
Langenberg C, Sharp SJ, Franks PW, Scott RA, Deloukas P, Forouhi NG, Froguel P, Groop LC et al.(2014). Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study. PLoS Med vol. 11, (5)
10.1371/journal.pmed.1001647
Falchi M, El-Sayed Moustafa JS, Takousis P, Pesce F, Bonnefond A, Andersson-Assarsson JC, Sudmant PH, Dorajoo R et al.(2014). Low copy number of the salivary amylase gene predisposes to obesity. Nat Genet vol. 46, (5) 492-497.
10.1038/ng.2939
Winkler TW, Day FR, Croteau-Chonka DC, Wood AR, Locke AE, Mägi R, Ferreira T, Fall T et al.(2014). Quality control and conduct of genome-wide association meta-analyses. Nat Protoc vol. 9, (5) 1192-1212.
10.1038/nprot.2014.071
Hanna DB, Hessol NA, Golub ET, Cocohoba JM, Cohen MH, Levine AM, Wilson TE, Young M et al. (2014). Increase in single-tablet regimen use and associated improvements in adherence-related outcomes in HIV-Infected Women. Journal of Acquired Immune Deficiency Syndromes. vol. 65, 587-596.
10.1097/QAI.0000000000000082
Rodriguez-Fontenla C, Calaza M, Evangelou E, Valdes AM, Arden N, Blanco FJ, Carr A, Chapman K et al.(2014). Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. Arthritis Rheumatol vol. 66, (4) 940-949.
10.1002/art.38300
Liu G, Yao L, Liu J, Jiang Y, Ma G, Genetic and Environmental Risk for Alzheimer's disease (GERAD1) Consortium, Chen Z, Zhao B et al.(2014). Cardiovascular disease contributes to Alzheimer's disease: evidence from large-scale genome-wide association studies. Neurobiol Aging vol. 35, (4) 786-792.
10.1016/j.neurobiolaging.2013.10.084
Holmes MV, Exeter HJ, Folkersen L, Nelson CP, Guardiola M, Cooper JA, Sofat R, Boekholdt SM et al.(2014). Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels. Circ Cardiovasc Genet vol. 7, (2) 144-150.
10.1161/CIRCGENETICS.113.000271
Sanders JL, Ding V, Arnold AM, Kaplan RC, Cappola AR, Kizer JR, Boudreau RM, Cushman M et al.(2014). Do changes in circulating biomarkers track with each other and with functional changes in older adults?. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 69 A, (2) 174-181.
10.1093/gerona/glt088
Rees E, Walters JTR, Chambert KD, O'Dushlaine C, Szatkiewicz J, Richards AL, Georgieva L, Mahoney-Davies G et al.(2014). CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1. Hum Mol Genet vol. 23, (6) 1669-1676.
10.1093/hmg/ddt540
Damotte V, Guillot-Noel L, Patsopoulos NA, Madireddy L, El Behi M, International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium 2, De Jager PL et al.(2014). A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes Immun vol. 15, (2) 126-132.
10.1038/gene.2013.70
Psychosis Endophenotypes International Consortium, Wellcome Trust Case-Control Consortium 2, Bramon E, Pirinen M, Strange A, Lin K, Freeman C, Bellenguez C et al.(2014). A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. Biol Psychiatry vol. 75, (5) 386-397.
10.1016/j.biopsych.2013.03.033
Keildson S, Fadista J, Ladenvall C, Hedman ÅK, Elgzyri T, Small KS, Grundberg E, Nica AC et al.(2014). Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity. Diabetes vol. 63, (3) 1154-1165.
10.2337/db13-1301
Power RA, Nagoshi C, DeFries JC, Plomin R, Wellcome Trust Case Control Consortium 2(2014). Genome-wide estimates of inbreeding in unrelated individuals and their association with cognitive ability. Eur J Hum Genet vol. 22, (3) 386-390.
10.1038/ejhg.2013.155
Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD et al.(2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. NATURE GENETICS vol. 46, (3) 234-+.
10.1038/ng.2897
Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K et al.(2014). Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature vol. 506, (7488) 376-381.
10.1038/nature12873
Beilina A, Rudenko IN, Kaganovich A, Civiero L, Chau H, Kalia SK, Kalia LV, Lobbestael E et al.(2014). Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. Proc Natl Acad Sci U S A vol. 111, (7) 2626-2631.
10.1073/pnas.1318306111
Wang T, Zhou B, Guo T, Bidlingmaier M, Wallaschofski H, Teumer A, Vasan RS, Kaplan RC(2014). A Robust Method for Genome-Wide Association Meta-Analysis With the Application to Circulating Insulin-Like Growth Factor I Concentrations. Genetic Epidemiology vol. 38, (2) 162-171.
10.1002/gepi.21766
Nalls MA, Saad M, Noyce AJ, Keller MF, Schrag A, Bestwick JP, Traynor BJ, Gibbs JR et al.(2014). Genetic comorbidities in Parkinson's disease. Hum Mol Genet vol. 23, (3) 831-841.
10.1093/hmg/ddt465
Harlaar N, Meaburn EL, Hayiou-Thomas ME, Wellcome Trust Case Control Consortium, Davis OSP, Docherty S, Hanscombe KB, Haworth CMA et al.(2014). Genome-wide association study of receptive language ability of 12-year-olds. J Speech Lang Hear Res vol. 57, (1) 96-105.
10.1044/1092-4388(2013/12-0303)
Medway C, Combarros O, Cortina-Borja M, Butler HT, Ibrahim-Verbaas CA, de Bruijn RFAG, Koudstaal PJ, van Duijn CM et al.(2014). The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project. Eur J Hum Genet vol. 22, (2) 216-220.
10.1038/ejhg.2013.116
Yuan W, Xia Y, Bell CG, Yet I, Ferreira T, Ward KJ, Gao F, Loomis AK et al.(2014). An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins. Nature Communications vol. 5,
10.1038/ncomms6719
Kim RS, Kaplan RC(2014). Analysis of secondary outcomes in nested case-control study designs. Statistics in Medicine vol. 33, (24) 4215-4226.
10.1002/sim.6231
Kuniholm MH, Xie X, Anastos K, Kaplan RC, Xue X, Kovacs A, Peters MG, Seaberg EC et al.(2014). Association of chronic hepatitis c infection with T-cell phenotypes in HIV-negative and HIV-positive women. Journal of Acquired Immune Deficiency Syndromes vol. 67, (3) 295-303.
10.1097/QAI.0000000000000310
Kiefer E, Hoover DR, Shi Q, Kuniholm MH, Augenbraun M, Cohen MH, Golub ET, Kaplan RC et al.(2014). Association of markers of hemostasis with death in HIV-infected women. Journal of Acquired Immune Deficiency Syndromes vol. 67, (3) 287-294.
10.1097/QAI.0000000000000306
Kaplan RC, Larissa Avilés-Santa M, Parrinello CM, Hanna DB, Jung M, Castañeda SF, Hankinson AL, Isasi CR et al.(2014). Body mass index, sex, and cardiovascular disease risk factors among hispanic/latino adults: Hispanic community health study/study of latinos. Journal of the American Heart Association vol. 3, (4)
10.1161/JAHA.114.000923
Tsaprouni LG, Yang TP, Bell J, Dick KJ, Kanoni S, Nisbet J, Viñuela A, Grundberg E et al.(2014). Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation. Epigenetics vol. 9, (10) 1382-1396.
10.4161/15592294.2014.969637
Beasley JM, Wedick NM, Rajpathak SN, Xue X, Holmes MD, Gunter MJ, Wylie-Rosett J, Rohan TE et al.(2014). Circulating IGF-axis protein levels and their relation with levels of plasma adipocytokines and macronutrient consumption in women. Growth Hormone and IGF Research vol. 24, (4) 142-149.
10.1016/j.ghir.2014.04.006
Steinberg S, De Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OPH, Lin K et al.(2014). Common variant at 16p11.2 conferring risk of psychosis. Molecular Psychiatry vol. 19, (1) 108-114.
10.1038/mp.2012.157
Beasley JM, Katz R, Shlipak M, Rifkin DE, Siscovick D, Kaplan R(2014). Dietary protein intake and change in estimated GFR in the Cardiovascular Health Study. Nutrition vol. 30, (7-8) 794-799.
10.1016/j.nut.2013.12.006
Bell JT, Loomis AK, Butcher LM, Gao F, Zhang B, Hyde CL, Sun J, Wu H et al.(2014). Differential methylation of the TRPA1 promoter in pain sensitivity. Nat Commun vol. 5,
10.1038/ncomms3978
Rodriguez CJ, Daviglus ML, Swett K, González HM, Gallo LC, Wassertheil-Smoller S, Giachello AL, Teng Y et al.(2014). Dyslipidemia patterns among Hispanics/Latinos of diverse background in the United States. American Journal of Medicine vol. 127, (12) 1186-1194.e1.
10.1016/j.amjmed.2014.07.026
Ganesh S, Chasman D, Larson M, Guo X, Verwoert G, Bis J, Gu X, Smith A et al.(2014). Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic Associations. American Journal of Human Genetics
10.1016/j.ajhg.2014.06.002
Wolber LE, Steves CJ, Tsai P-C, Deloukas P, Spector TD, Bell JT, Williams FMK(2014). Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem. PLoS One vol. 9, (9)
10.1371/journal.pone.0105729
Gardner M, Bann D, Wiley L, Cooper R, Hardy R, Nitsch D, Martin-Ruiz C, Shiels P et al.(2014). Gender and telomere length: Systematic review and meta-analysis. Experimental Gerontology vol. 51, (1) 15-27.
10.1016/j.exger.2013.12.004
Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Cooke Bailey JN, Wojciechowski R, Vitart V, Nag A et al.(2014). Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nature Genetics vol. 46, (10) 1126-1130.
10.1038/ng.3087
Shin S-Y, Petersen A-K, Wahl S, Zhai G, Römisch-Margl W, Small KS, Döring A, Kato BS et al.(2014). Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids. Genome Med vol. 6, (3)
10.1186/gm542
Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, Destefano AL, Kara E et al.(2014). Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nature Genetics vol. 46, (9) 989-993.
10.1038/ng.3043
Shaked I, Hanna DB, Gleißner C, Marsh B, Plants J, Tracy D, Anastos K, Cohen M et al.(2014). Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 34, (5) 1085-1092.
10.1161/ATVBAHA.113.303153
Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JNC, Gibson J et al.(2014). Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nature Communications vol. 5,
10.1038/ncomms5883
Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH, Teumer A, Winkler TW et al.(2014). Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genetics vol. 10, (7) 1-12.
10.1371/journal.pgen.1004508
Schneiderman N, Llabre M, Cowie CC, Barnhart J, Carnethon M, Gallo LC, Giachello AL, Heiss G et al.(2014). Prevalence of diabetes among hispanics/latinos from diverse backgrounds: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Diabetes Care vol. 37, (8) 2233-2239.
10.2337/dc13-2939
Sorlie PD, Allison MA, Avilés-Santa ML, Cai J, Daviglus ML, Howard AG, Kaplan R, Lavange LM et al.(2014). Prevalence of hypertension, awareness, treatment, and control in the Hispanic community health study/study of Latinos. American Journal of Hypertension vol. 27, (6) 793-800.
10.1093/ajh/hpu003
Heiss G, Snyder ML, Teng Y, Schneiderman N, Llabre MM, Cowie C, Carnethon M, Kaplan R et al.(2014). Prevalence of metabolic syndrome among hispanics/latinos of diverse background: The Hispanic Community Health Study/Study of Latinos. Diabetes Care vol. 37, (8) 2391-2399.
10.2337/dc13-2505
Kaplan RC(2014). Public health: An agenda to promote Hispanic cardiovascular health. Nature Reviews Cardiology vol. 11, (10) 560-562.
10.1038/nrcardio.2014.126
Shendre A, Irvin MR, Aouizerat BE, Wiener HW, Vazquez AI, Anastos K, Lazar J, Liu C et al.(2014). RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS). Atherosclerosis vol. 233, (2) 666-672.
10.1016/j.atherosclerosis.2014.01.035
Almlöf JC, Lundmark P, Lundmark A, Ge B, Pastinen T, Cardiogenics Consortium, Goodall AH, Cambien F et al.(2014). Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes. PLoS One vol. 9, (7)
10.1371/journal.pone.0102612
Kaplan RC, Bangdiwala SI, Barnhart JM, Castañeda SF, Gellman MD, Lee DJ, Pérez-Stable EJ, Talavera GA et al.(2014). Smoking among U.S. hispanic/latino adults: The hispanic community health study/study of latinos. American Journal of Preventive Medicine vol. 46, (5) 496-506.
10.1016/j.amepre.2014.01.014
Wassertheil-Smoller S, Kaplan RC, Salazar CR(2014). Stroke findings in the women's health initiative. Seminars in Reproductive Medicine vol. 32, (6) 438-446.
10.1055/s-0034-1384627
Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Desai S et al. (2014). T-cell activation, both pre- and post-HAART levels, correlates with carotid artery stiffness over 6.5 years among HIV-infected women in the WIHS. Journal of Acquired Immune Deficiency Syndromes. vol. 67, 349-356.
10.1097/QAI.0000000000000311
Isasi CR, Carnethon MR, Ayala GX, Arredondo E, Bangdiwala SI, Daviglus ML, Delamater AM, Eckfeldt JH et al.(2014). The Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth): Design, objectives, and procedures. Annals of Epidemiology vol. 24, (1) 29-35.
10.1016/j.annepidem.2013.08.008
Kwan K, Chlebowski RT, McTiernan A, Rodabough RJ, La Monte MJ, Martin LW, Bell C, Lane DS et al.(2014). Walking speed, physical activity, and breast cancer in postmenopausal women. European Journal of Cancer Prevention vol. 23, (1) 49-52.
10.1097/CEJ.0b013e328361627e
Shah N, Rice T, Tracy D, Rohan T, B¿žková P, Newman A, Kaplan RC(2013). Sleep and insulin-like growth factors in the cardiovascular health study. Journal of Clinical Sleep Medicine vol. 9, (12) 1245-1251.
10.5664/jcsm.3260
Erdmann J, Stark K, Esslinger UB, Rumpf PM, Koesling D, de Wit C, Kaiser FJ, Braunholz D et al.(2013). Dysfunctional nitric oxide signalling increases risk of myocardial infarction. Nature vol. 504, (7480) 432-436.
10.1038/nature12722
Rodriguez-Fontenla C, Calaza M, Evangelou E, Valdes AM, Arden N, Blanco FJ, Carr A, Chapman K et al.(2013). Assessment of osteoarthritis candidate genes in a meta-analysis of 9 genome-wide association studies. Arthritis Rheum
10.1002/art.38300
Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, Busche S, Yuan W et al.(2013). Erratum: Global analysis of dna methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements ((Journal of Human Genetics (2013) 93 (876-890)). American Journal of Human Genetics vol. 93, (6)
10.1016/j.ajhg.2013.11.003
Lambert J-C, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, DeStefano AL et al.(2013). Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. NATURE GENETICS vol. 45, (12) 1452-U206.
10.1038/ng.2802
Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, Busche S, Yuan W et al.(2013). Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genet vol. 93, (5) 876-890.
10.1016/j.ajhg.2013.10.004
International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS et al.(2013). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet vol. 45, (11) 1353-1360.
10.1038/ng.2770
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S et al.(2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics vol. 45, (11) 1345-1353.
10.1038/ng.2795
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S et al.(2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet vol. 45, (11) 1345-1352.
10.1038/ng.2795
Global Lipids Genetics Consortium, Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A et al.(2013). Discovery and refinement of loci associated with lipid levels. Nat Genet vol. 45, (11) 1274-1283.
10.1038/ng.2797
Strange A, Bellenguez C, Sim X, Luben R, Hysi PG, Ramdas WD, van Koolwijk LME, Freeman C et al.(2013). Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. Human Molecular Genetics vol. 22, (22) 4653-4660.
10.1093/hmg/ddt293
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23566
Bradley DT, Hughes AE, Badger SA, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF et al.(2013). A variant in LDLR is associated with abdominal aortic aneurysm. Circ Cardiovasc Genet vol. 6, (5) 498-504.
10.1161/CIRCGENETICS.113.000165
Ho JE, Chen W-Y, Chen M-H, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E et al.(2013). Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest vol. 123, (10) 4208-4218.
10.1172/JCI67119
Lindner C, Thiagarajah S, Wilkinson JM, arcOGEN Consortium, Wallis GA, Cootes TF(2013). Development of a fully automatic shape model matching (FASMM) system to derive statistical shape models from radiographs: application to the accurate capture and global representation of proximal femur shape. Osteoarthritis Cartilage vol. 21, (10) 1537-1544.
10.1016/j.joca.2013.08.008
Ripke S, O'Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, Bergen SE, Collins AL et al.(2013). Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet vol. 45, (10) 1150-1159.
10.1038/ng.2742
Evans DM, Brion MJA, Paternoster L, Kemp JP, McMahon G, Munafò M, Whitfield JB, Medland SE et al.(2013). Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet vol. 9, (10)
10.1371/journal.pgen.1003919
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP et al.(2013). Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation vol. 128, (12) 1310-1324.
10.1161/CIRCULATIONAHA.113.002251
Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC et al.(2013). Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet vol. 382, (9894) 790-796.
10.1016/S0140-6736(13)60681-9
Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME et al.(2013). Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Hum Mol Genet vol. 22, (16) 3381-3393.
10.1093/hmg/ddt189
Hu YJ, Berndt SI, Gustafsson S, Ganna A, Hirschhorn J, North KE, Ingelsson E, Lin DY et al.(2013). Meta-analysis of gene-level associations for rare variants based on single-variant statistics. American Journal of Human Genetics vol. 93, (2) 236-248.
10.1016/j.ajhg.2013.06.011
Cheng C-Y, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJM et al.(2013). Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet vol. 93, (2) 264-277.
10.1016/j.ajhg.2013.06.016
Broer L, Demerath EW, Garcia ME, Homuth G, Kaplan RC, Lunetta KL, Tanaka T, Tranah GJ et al.(2013). Association of heat shock proteins with all-cause mortality. Age vol. 35, (4) 1367-1376.
10.1007/s11357-012-9417-7
Menni C, Kastenmüller G, Petersen AK, Bell JT, Psatha M, Tsai P-C, Gieger C, Schulz H et al.(2013). Metabolomic markers reveal novel pathways of ageing and early development in human populations. Int J Epidemiol vol. 42, (4) 1111-1119.
10.1093/ije/dyt094
Jones GT, Bown MJ, Gretarsdottir S, Romaine SPR, Helgadottir A, Yu G, Tromp G, Norman PE et al.(2013). A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Hum Mol Genet vol. 22, (14) 2941-2947.
10.1093/hmg/ddt141
Agalliu I, Xue X, Cushman M, Cornell E, Hsing AW, Kaplan RC, Anastos K, Rajpathak S et al.(2013). Detectability and reproducibility of plasma levels of chemokines and soluble receptors. Results in Immunology vol. 3, 79-84.
10.1016/j.rinim.2013.07.001
Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Rob Taal H, Huikari V et al.(2013). Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics vol. 22, (13) 2735-2747.
10.1093/hmg/ddt104
International Genetics of Ankylosing Spondylitis Consortium (IGAS), Cortes A, Hadler J, Pointon JP, Robinson PC, Karaderi T, Leo P, Cremin K et al.(2013). Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet vol. 45, (7) 730-738.
10.1038/ng.2667
Paul DS, Albers CA, Rendon A, Voss K, Stephens J, HaemGen Consortium, van der Harst P, Chambers JC et al.(2013). Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res vol. 23, (7) 1130-1141.
10.1101/gr.155127.113
Heilmann S, Nyholt DR, Brockschmidt FF, Hillmer AM, Herold C, Maan Consortium, Becker T, Martin NG et al.(2013). No genetic support for a contribution of prostaglandins to the aetiology of androgenetic alopecia. Br J Dermatol vol. 169, (1) 222-224.
10.1111/bjd.12292
Paul D, Albers CA, Rendon A, Voss K, Stephens J, Van der Harst P, Chambers JC, Soranzo N et al. (2013). The epigenetic landscape of platelet and red blood cell traits. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. vol. 11, 349-349.
Dastani Z, Johnson T, Kronenberg F, Nelson CP, Assimes TL, März W, CARDIoGRAM Consortium, ADIPOGen Consortium et al.(2013). The shared allelic architecture of adiponectin levels and coronary artery disease. Atherosclerosis vol. 229, (1) 145-148.
10.1016/j.atherosclerosis.2013.03.034
Traylor M, Bevan S, Rothwell PM, Sudlow C, Dichgans M, Markus HS, Lewis CM(2013). Using Phenotypic Heterogeneity to Increase the Power of Genome-Wide Association Studies: Application to Age at Onset of Ischaemic Stroke Subphenotypes. Genetic Epidemiology vol. 37, (5) 495-503.
10.1002/gepi.21729
Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra H-J, Shakhbazov K et al.(2013). GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science vol. 340, (6139) 1467-1471.
10.1126/science.1235488
Hinks A, Cobb J, Marion MC, Prahalad S, Sudman M, Bowes J, Martin P, Comeau ME et al.(2013). Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet vol. 45, (6) 664-669.
10.1038/ng.2614
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Singh Pahwa J, Moskvina V et al.(2013). Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093)). Nature Genetics vol. 45, (6)
10.1038/ng0613-712a
Elliott KS, Chapman K, Day-Williams A, Panoutsopoulou K, Southam L, Lindgren CM, Arden N, Aslam N et al.(2013). Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data. Ann Rheum Dis vol. 72, (6) 935-941.
10.1136/annrheumdis-2012-202081
Tanaka T, Ngwa JS, van Rooij FJA, Zillikens MC, Wojczynski MK, Frazier-Wood AC, Houston DK, Kanoni S et al.(2013). Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr vol. 97, (6) 1395-1402.
10.3945/ajcn.112.052183
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T et al.(2013). Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLoS Genetics vol. 9, (6)
10.1371/journal.pgen.1003500
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19179
Klebe S, Golmard JL, Nalls MA, Saad M, Singleton AB, Bras JM, Hardy J, Simon-Sanchez J et al.(2013). The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism. Journal of Neurology, Neurosurgery and Psychiatry vol. 84, (6) 666-673.
10.1136/jnnp-2012-304475
Parrinello CM, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC et al.(2013). Treatment-related changes in serum lipids and inflammation: Clinical relevance remains unclear. Analyses from the Women's Interagency HIV study. AIDS vol. 27, (9) 1516-1519.
10.1097/QAD.0b013e32835fd8a9
Zou F, Belbin O, Carrasquillo MM, Culley OJ, Hunter TA, Ma L, Bisceglio GD, Allen M et al.(2013). Linking Protective GAB2 Variants, Increased Cortical GAB2 Expression and Decreased Alzheimer's Disease Pathology. PLoS ONE vol. 8, (5)
10.1371/journal.pone.0064802
Mechelli R, Umeton R, Policano C, Annibali V, Coarelli G, Ricigliano VAG, Vittori D, Fornasiero A et al.(2013). A "Candidate-Interactome" Aggregate Analysis of Genome-Wide Association Data in Multiple Sclerosis. PLoS ONE vol. 8, (5)
10.1371/journal.pone.0063300
Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP et al.(2013). Genetic predisposition to higher blood pressure increases coronary artery disease risk. Hypertension vol. 61, (5) 995-1001.
10.1161/HYPERTENSIONAHA.111.00275
Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, Young R, Ho WK et al.(2013). Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India. DIABETES vol. 62, (5) 1746-1755.
10.2337/db12-1077
Berndt SI, Gustafsson S, Maegi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL et al.(2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. NATURE GENETICS vol. 45, (5) 501-U69.
10.1038/ng.2606
Banerjee D, Biggs ML, Mercer L, Mukamal K, Kaplan R, Barzilay J, Kuller L, Kizer JR et al.(2013). Insulin resistance and risk of incident heart failure cardiovascular health study. Circulation: Heart Failure vol. 6, (3) 364-370.
10.1161/CIRCHEARTFAILURE.112.000022
Kuniholm MH, Parrinello CM, Anastos K, Augenbraun M, Plankey M, Nowicki M, Peters M, Golub ET et al.(2013). Hepatitis C Viremia Is Associated with Cytomegalovirus IgG Antibody Levels in HIV-Infected Women. PLoS ONE vol. 8, (4)
10.1371/journal.pone.0061973
Ochs-Balcom HM, Preus L, Wactawski-Wende J, Nie J, Johnson NA, Zakharia F, Tang H, Carlson C et al.(2013). Association of DXA-derived bone mineral density and fat mass with african ancestry. Journal of Clinical Endocrinology and Metabolism vol. 98, (4)
10.1210/jc.2012-3921
Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM et al.(2013). Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. Neurobiol Aging vol. 34, (4) 1309.e1-1309.e7.
10.1016/j.neurobiolaging.2012.08.010
Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Cohen M et al.(2013). Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the Women's Interagency HIV Study (WIHS). Journal of Clinical Endocrinology and Metabolism vol. 98, (4)
10.1210/jc.2012-3195
Holmans P, Moskvina V, Jones L, Sharma M, International Parkinson's Disease Genomics Consortium, Vedernikov A, Buchel F, Saad M et al.(2013). A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet vol. 22, (5) 1039-1049.
10.1093/hmg/dds492
Kiefer EM, Shi Q, Hoover DR, Kaplan R, Tracy R, Augenbraun M, Liu C, Nowicki M et al.(2013). Association of hepatitis C with markers of hemostasis in hiv-infected and uninfected women in the Women's interagency HIV study (WIHS). Journal of Acquired Immune Deficiency Syndromes vol. 62, (3) 301-310.
10.1097/QAI.0b013e31827fdd61
Verhoeven VJM, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, MacGregor S, Hewitt AW et al.(2013). Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet vol. 45, (3) 314-318.
10.1038/ng.2554
Chapman J, Rees E, Harold D, Ivanov D, Gerrish A, Sims R, Hollingworth P, Stretton A et al.(2013). A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk. Hum Mol Genet vol. 22, (4) 816-824.
10.1093/hmg/dds476
Lee SH, Harold D, Nyholt DR, ANZGene Consortium, International Endogene Consortium, Genetic and Environmental Risk for Alzheimer's disease Consortium, Goddard ME, Zondervan KT et al.(2013). Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis. Hum Mol Genet vol. 22, (4) 832-841.
10.1093/hmg/dds491
Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z et al.(2013). Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts. PLoS Medicine vol. 10, (2)
10.1371/journal.pmed.1001383
LeishGEN Consortium, Wellcome Trust Case Control Consortium 2, Fakiola M, Strange A, Cordell HJ, Miller EN, Pirinen M, Su Z et al.(2013). Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet vol. 45, (2) 208-213.
10.1038/ng.2518
Gamazon ER, Daneshjou R, Cavallari LH, Limdi NA, Wadelius M, Johnson JA, Klein TE, Scott S et al. (2013). EXPRESSION QUANTITATIVE TRAIT LOCI ANALYSIS OF STABLE WARFARIN DOSE IDENTIFIES NOVEL ASSOCIATIONS: FINDING SIGNAL WITHIN THE NOISE. CLINICAL PHARMACOLOGY & THERAPEUTICS. vol. 93, S27-S27.
Pérez-Andreu V, Teruel R, Corral J, Roldán V, García-Barberá N, Salloum-Asfar S, Gómez-Lechón MJ, Bourgeois S et al.(2013). miR-133a regulates vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1), a key protein in the vitamin K cycle. Mol Med vol. 18, 1466-1472.
10.2119/molmed.2012.00062
Ruark E, Snape K, Humburg P, Loveday C, Bajrami I, Brough R, Rodrigues DN, Renwick A et al.(2013). Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature vol. 493, (7432) 406-410.
10.1038/nature11725
Nettleton JA, Hivert M-F, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T, Wojczynski MK, Hruby A et al.(2013). Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. Am J Epidemiol vol. 177, (2) 103-115.
10.1093/aje/kws297
Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C et al.(2013). TREM2 variants in Alzheimer's disease. N Engl J Med vol. 368, (2) 117-127.
10.1056/NEJMoa1211851
Shah N, Redline S, Yaggi HK, Wu R, Zhao CG, Ostfeld R, Menegus M, Tracy D et al.(2013). Erratum: Obstructive sleep apnea and acute myocardial infarction severity: Ischemic preconditioning? (Sleep and Breathing (DOI: 10.1007/s11325-012-0770-7)). Sleep and Breathing vol. 17, (3)
10.1007/s11325-012-0793-0
Glass D, Viñuela A, Davies MN, Ramasamy A, Parts L, Knowles D, Brown AA, Hedman ÅK et al.(2013). Gene expression changes with age in skin, adipose tissue, blood and brain. Genome Biology vol. 14, (7)
10.1186/gb-2013-14-7-r75
Garnier S, Truong V, Brocheton J, Zeller T, Rovital M, Wild PS, Ziegler A, Cardiogenics Consortium et al.(2013). Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes. PLoS Genet vol. 9, (1)
10.1371/journal.pgen.1003240
Faraco J, Lin L, Kornum BR, Kenny EE, Trynka G, Einen M, Rico TJ, Lichtner P et al.(2013). ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genet vol. 9, (2)
10.1371/journal.pgen.1003270
CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E et al.(2013). Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet vol. 45, (1) 25-33.
10.1038/ng.2480
Hudson G, Panoutsopoulou K, Wilson I, Southam L, Rayner NW, Arden N, Birrell F, Carluke I et al.(2013). No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls. Ann Rheum Dis vol. 72, (1) 136-139.
10.1136/annrheumdis-2012-201932
Huertas-Vazquez A, Nelson CP, Guo X, Reinier K, Uy-Evanado A, Teodorescu C, Ayala J, Jerger K et al.(2013). Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease. PLoS One vol. 8, (4)
10.1371/journal.pone.0059905
Shah N, Redline S, Yaggi HK, Wu R, Zhao CG, Ostfeld R, Menegus M, Tracy D et al.(2013). Obstructive sleep apnea and acute myocardial infarction severity: Ischemic preconditioning?. Sleep and Breathing vol. 17, (2) 819-826.
10.1007/s11325-012-0770-7
InterAct Consortium, Scott RA, Langenberg C, Sharp SJ, Franks PW, Rolandsson O, Drogan D, van der Schouw YT et al.(2013). The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study. Diabetologia vol. 56, (1) 60-69.
10.1007/s00125-012-2715-x
van der Loos MJHM, Rietveld CA, Eklund N, Koellinger PD, Rivadeneira F, Abecasis GR, Ankra-Badu GA, Baumeister SE et al.(2013). The molecular genetic architecture of self-employment. PLoS One vol. 8, (4)
10.1371/journal.pone.0060542
Drong AW, Nicholson G, Hedman AK, Meduri E, Grundberg E, Small KS, Shin S-Y, Bell JT et al.(2013). The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue. PLoS One vol. 8, (2)
10.1371/journal.pone.0055923
van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U et al.(2012). Seventy-five genetic loci influencing the human red blood cell. Nature vol. 492, (7429) 369-375.
10.1038/nature11677
Nürnberg ST, Rendon A, Smethurst PA, Paul DS, Voss K, Thon JN, Lloyd-Jones H, Sambrook JG et al.(2012). A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood vol. 120, (24) 4859-4868.
10.1182/blood-2012-01-401893
Parrinello CM, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC et al.(2012). Association of subclinical atherosclerosis with lipid levels amongst antiretroviral-treated and untreated HIV-infected women in the Women's Interagency HIV study. Atherosclerosis vol. 225, (2) 408-411.
10.1016/j.atherosclerosis.2012.09.035
Maller JB, McVean G, Byrnes J, Vukcevic D, Palin K, Su Z, Howson JMM, Auton A et al.(2012). Bayesian refinement of association signals for 14 loci in 3 common diseases. NATURE GENETICS vol. 44, (12) 1294-1301.
10.1038/ng.2435
Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E et al.(2012). High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet vol. 44, (12) 1336-1340.
10.1038/ng.2462
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y et al.(2012). Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nature Genetics vol. 44, (12) 1341-1348.
10.1038/ng.2467
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y et al.(2012). Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet vol. 44, (12) 1341-1348.
10.1038/ng.2467
Cooper JD, Simmonds MJ, Walker NM, Burren O, Brand OJ, Guo H, Wallace C, Stevens H et al.(2012). Seven newly identified loci for autoimmune thyroid disease. Human Molecular Genetics vol. 21, (23) 5202-5208.
10.1093/hmg/dds357
Braenne I, Medack A, Stark K, Field S, Tuna S, Deloukas P, Samani NJ, Schunkert H et al. (2012). Ldlr Splice-Site Mutation (ivs9-1g>A) Identified by Whole-Exome Sequencing in an Extended Family with Myocardial Infarction. CIRCULATION. vol. 126,
Braenne I, Medack A, Stark K, Field S, Tuna S, Deloukas P, Samani NJ, Hengstenberg C et al. (2012). Whole-Exome Sequencing in an Extended Family with Myocardial Infarction Identified a Potential Functional Mutation in PDE5A. CIRCULATION. vol. 126,
Daviglus ML, Talavera GA, Avilés-Santa ML, Allison M, Cai J, Criqui MH, Gellman M, Giachello AL et al.(2012). Prevalence of major cardiovascular risk factors and cardiovascular diseases among Hispanic/Latino individuals of diverse backgrounds in the United States. JAMA - Journal of the American Medical Association vol. 308, (17) 1775-1784.
10.1001/jama.2012.14517
Ma Y, Hébert JR, Manson JE, Balasubramanian R, Liu S, Lamonte MJ, Bird CE, Ockene JK et al.(2012). Determinants of racial/ethnic disparities in incidence of diabetes in postmenopausal women in the U.S.: The women's health initiative 1993-2009. Diabetes Care vol. 35, (11) 2226-2234.
10.2337/dc12-0412
Strange A, Riley BP, Spencer CCA, Morris DW, Pirinen M, O'Dushlaine CT, Su Z, Maher BS et al.(2012). Genome-Wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia. BIOLOGICAL PSYCHIATRY vol. 72, (8) 620-628.
10.1016/j.biopsych.2012.05.035
Su Z, Gay LJ, Strange A, Palles C, Band G, Whiteman DC, Lescai F, Langford C et al.(2012). Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet vol. 44, (10) 1131-1136.
10.1038/ng.2408
Grundberg E, Small KS, Hedman ÅK, Nica AC, Buil A, Keildson S, Bell JT, Yang T-P et al.(2012). Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet vol. 44, (10) 1084-1089.
10.1038/ng.2394
arcOGEN Consortium, arcOGEN Collaborators, Zeggini E, Panoutsopoulou K, Southam L, Rayner NW, Day-Williams AG, Lopes MC et al.(2012). Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet vol. 380, (9844) 815-823.
10.1016/S0140-6736(12)60681-3
Rajpathak SN, He M, Sun Q, Kaplan RC, Muzumdar R, Rohan TE, Gunter MJ, Pollak M et al.(2012). Insulin-like growth factor axis and risk of type 2 diabetes in women. Diabetes vol. 61, (9) 2248-2254.
10.2337/db11-1488
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, MäGi R, Strawbridge RJ et al.(2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics vol. 44, (9) 991-1005.
10.1038/ng.2385
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H et al.(2012). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet vol. 44, (9) 981-990.
10.1038/ng.2383
Kaplan RC, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC et al.(2012). Potential cardiovascular disease risk markers among HIV-infected women initiating antiretroviral treatment. Journal of Acquired Immune Deficiency Syndromes vol. 60, (4) 359-368.
10.1097/QAI.0b013e31825b03be
Voight BF, Kang HM, Ding J, Palmer CD, Sidore C, Chines PS, Burtt NP, Fuchsberger C et al.(2012). The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits. PLOS GENETICS vol. 8, (8) Article ARTN e1002793,
10.1371/journal.pgen.1002793
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5349
Lyons PA, Rayner TF, Trivedi S, Holle JU, Watts RA, Jayne DRW, Baslund B, Brenchley P et al.(2012). Genetically distinct subsets within ANCA-associated vasculitis. N Engl J Med vol. 367, (3) 214-223.
10.1056/NEJMoa1108735
Ho GYF, Wang T, Gunter MJ, Strickler HD, Cushman M, Kaplan RC, Wassertheil-Smoller S, Xue X et al.(2012). Adipokines linking obesity with colorectal cancer risk in postmenopausal women. Cancer Research vol. 72, (12) 3029-3037.
10.1158/0008-5472.CAN-11-2771
Parrinello CM, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt PW et al.(2012). Cytomegalovirus immunoglobulin G antibody is associated with subclinical carotid artery disease among HIV-infected women. Journal of Infectious Diseases vol. 205, (12) 1788-1796.
10.1093/infdis/jis276
Manning AK, Hivert M-F, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu C-T et al.(2012). A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. NATURE GENETICS vol. 44, (6) 659-U81.
10.1038/ng.2274
Kaplan RC, Bùžková P, Cappola AR, Strickler HD, McGinn AP, Mercer LD, Arnold AM, Pollak MN et al.(2012). Decline in circulating insulin-like growth factors and mortality in older adults: Cardiovascular health study all-stars study. Journal of Clinical Endocrinology and Metabolism vol. 97, (6) 1970-1976.
10.1210/jc.2011-2967
Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C et al.(2012). A genome-wide association meta-analysis identifies new childhood obesity loci. NATURE GENETICS vol. 44, (5) 526-+.
10.1038/ng.2247
Wassel CL, Lamina C, Nambi V, Coassin S, Mukamal KJ, Ganesh SK, Jacobs DR, Franceschini N et al.(2012). Genetic determinants of the ankle-brachial index: A meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium. Atherosclerosis vol. 222, (1) 138-147.
10.1016/j.atherosclerosis.2012.01.039
Li R, Brockschmidt FF, Kiefer AK, Stefansson H, Nyholt DR, Song K, Vermeulen SH, Kanoni S et al.(2012). Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. PLoS Genet vol. 8, (5)
10.1371/journal.pgen.1002746
Kölsch H, Lehmann DJ, Ibrahim-Verbaas CA, Combarros O, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M et al.(2012). Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project. J Neural Transm (Vienna) vol. 119, (4) 473-479.
10.1007/s00702-011-0732-4
Berger JS, McGinn AP, Howard BV, Kuller L, Manson JE, Otvos J, Curb JD, Eaton CB et al.(2012). Lipid and lipoprotein biomarkers and the risk of ischemic stroke in postmenopausal women. Stroke vol. 43, (4) 958-966.
10.1161/STROKEAHA.111.641324
Albers CA, Paul DS, Schulze H, Freson K, Stephens JC, Smethurst PA, Jolley JD, Cvejic A et al. (2012). Thrombocytopenia with Absent Radii (TAR) syndrome is cause by compound inheritance of low-frequency regulatory SNPs and a rare null mutation in exon-junction complex subunit RBM8A. BRITISH JOURNAL OF HAEMATOLOGY. vol. 157, 9-9.
Charchar FJ, Bloomer LD, Barnes TA, Cowley MJ, Nelson CP, Wang Y, Denniff M, Debiec R et al.(2012). Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome. Lancet vol. 379, (9819) 915-922.
10.1016/S0140-6736(11)61453-0
Sarwar N, Butterworth AS, Freitag DF, Gregson J, Willeit P, Gorman DN, Gao P, Saleheen D et al.(2012). Interleukin-6 receptor pathways in coronary heart disease: A collaborative meta-analysis of 82 studies. The Lancet vol. 379, (9822) 1205-1213.
10.1016/S0140-6736(11)61931-4
Albers CA, Paul DS, Schulze H, Freson K, Stephens JC, Smethurst PA, Jolley JD, Cvejic A et al.(2012). Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome. Nat Genet vol. 44, (4) 435-S2.
10.1038/ng.1083
International Stroke Genetics Consortium (ISGC), Wellcome Trust Case Control Consortium 2 (WTCCC2), Bellenguez C, Bevan S, Gschwendtner A, Spencer CCA, Burgess AI, Pirinen M et al.(2012). Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet vol. 44, (3) 328-333.
10.1038/ng.1081
Cavallari LH, Perera M, Wadelius M, Deloukas P, Taube G, Patel SR, Aquino-Michaels K, Viana MAG et al.(2012). Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans. Pharmacogenet Genomics vol. 22, (2) 152-158.
10.1097/FPC.0b013e32834f288f
Stolk L, Perry JRB, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L et al.(2012). Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet vol. 44, (3) 260-268.
10.1038/ng.1051
Davison LJ, Wallace C, Cooper JD, Cope NF, Wilson NK, Smyth DJ, Howson JMM, Saleh N et al.(2012). Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene. Hum Mol Genet vol. 21, (2) 322-333.
10.1093/hmg/ddr468
Clark C, Palta P, Joyce CJ, Scott C, Grundberg E, Deloukas P, Palotie A, Coffey AJ(2012). A comparison of the whole genome approach of MeDIP-seq to the targeted approach of the Infinium HumanMethylation450 BeadChip(®) for methylome profiling. PLoS One vol. 7, (11)
10.1371/journal.pone.0050233
Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN et al.(2012). A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One vol. 7, (1)
10.1371/journal.pone.0029202
Greliche N, Zeller T, Wild PS, Rotival M, Schillert A, Ziegler A, Cardiogenics Consortium, Deloukas P et al.(2012). Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression. PLoS One vol. 7, (9)
10.1371/journal.pone.0045863
Bell JT, Tsai P-C, Yang T-P, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G et al.(2012). Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet vol. 8, (4)
10.1371/journal.pgen.1002629
Parts L, Hedman ÅK, Keildson S, Knights AJ, Abreu-Goodger C, van de Bunt M, Guerra-Assunção JA, Bartonicek N et al.(2012). Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet vol. 8, (5)
10.1371/journal.pgen.1002704
Liskova P, Gwilliam R, Filipec M, Jirsova K, Reinstein Merjava S, Deloukas P, Webb TR, Bhattacharya SS et al.(2012). High prevalence of posterior polymorphous corneal dystrophy in the Czech Republic; linkage disequilibrium mapping and dating an ancestral mutation. PLoS One vol. 7, (9)
10.1371/journal.pone.0045495
Heun R, Kölsch H, Ibrahim-Verbaas CA, Combarros O, Aulchenko YS, Breteler M, Schuur M, van Duijn CM et al.(2012). Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis Project. Int J Mol Epidemiol Genet vol. 3, (1) 39-47.
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ et al.(2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics
10.1038/ng.2385
Dastani Z, Hivert M-F, Timpson N, Perry JRB, Yuan X, Scott RA, Henneman P, Heid IM et al.(2012). Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet vol. 8, (3)
10.1371/journal.pgen.1002607
Stranger BE, Montgomery SB, Dimas AS, Parts L, Stegle O, Ingle CE, Sekowska M, Smith GD et al.(2012). Patterns of cis regulatory variation in diverse human populations. PLoS Genet vol. 8, (4)
10.1371/journal.pgen.1002639
Almlöf JC, Lundmark P, Lundmark A, Ge B, Maouche S, Göring HHH, Liljedahl U, Enström C et al.(2012). Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression. PLoS One vol. 7, (12)
10.1371/journal.pone.0052260
Lane S, Al-Zubiedi S, Hatch E, Matthews I, Jorgensen AL, Deloukas P, Daly AK, Park BK et al.(2012). The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors. Br J Clin Pharmacol vol. 73, (1) 66-76.
10.1111/j.1365-2125.2011.04051.x
Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R et al.(2012). The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. J Alzheimers Dis vol. 28, (2) 377-387.
10.3233/JAD-2011-110824
Lehmann DJ, Schuur M, Warden DR, Hammond N, Belbin O, Kölsch H, Lehmann MG, Wilcock GK et al.(2012). Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. Neurobiol Aging vol. 33, (1) 202.e1-202.13.
10.1016/j.neurobiolaging.2010.07.018
Keller MF, Saad M, Bras J, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Büchel F et al.(2012). Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Human Molecular Genetics vol. 21, (22) 4996-5009.
10.1093/hmg/dds335
Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC et al.(2011). Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nat Genet vol. 44, (1) 3-5.
10.1038/ng.1037
Paternoster L, Standl M, Chen C-M, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC et al.(2011). Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet vol. 44, (2) 187-192.
10.1038/ng.1017
Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U et al.(2011). New gene functions in megakaryopoiesis and platelet formation. NATURE vol. 480, (7376) 201-208.
10.1038/nature10659
Rotival M, Zeller T, Wild PS, Maouche S, Szymczak S, Schillert A, Castagné R, Deiseroth A et al.(2011). Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet vol. 7, (12)
10.1371/journal.pgen.1002367
Bown MJ, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Gretarsdottir S, Badger SA et al.(2011). Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. American Journal of Human Genetics vol. 89, (5) 619-627.
10.1016/j.ajhg.2011.10.002
Trynka G, Hunt KA, Bockett NA, Romanos J, Mistry V, Szperl A, Bakker SF, Bardella MT et al.(2011). Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet vol. 43, (12) 1193-1201.
10.1038/ng.998
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC et al.(2011). Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (Nature Genetics (2010) 42 (949-960)). Nature Genetics vol. 43, (11)
10.1038/ng1111-1164a
Crystal HA, Weedon J, Holman S, Manly J, Valcour V, Cohen M, Anastos K, Liu C et al.(2011). Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women. Journal of NeuroVirology vol. 17, (5) 469-476.
10.1007/s13365-011-0052-3
Small KS, Hedman AK, Grundberg E, Nica AC, Thorleifsson G, Kong A, Thorsteindottir U, Shin SY et al.(2011). Erratum: Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes (Nature Genetics (2011) 43 (561-564)). Nature Genetics vol. 43, (10)
10.1038/ng1011-1040c
Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME et al.(2011). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes vol. 60, (10) 2624-2634.
10.2337/db11-0415
Kooner JS, Saleheen D, Sim X, Sehmi J, Zhang WH, Frossard P, Been LF, Chia KS et al.(2011). Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. NAT GENET vol. 43, (10) 984-U94.
10.1038/ng.921
Small KS, Hedman AK, Grundberg E, Nica AC, Thorleifsson G, Kong A, Thorsteindottir U, Shin S-Y et al.(2011). Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes (vol 43, pg 561, 2011). NATURE GENETICS vol. 43, (10) 1040-1040.
International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV et al.(2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature vol. 478, (7367) 103-109.
10.1038/nature10405
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13815
Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, Estrada K, Helgadottir HT, Hofman A et al.(2011). A variant in MCF2L is associated with osteoarthritis. Am J Hum Genet vol. 89, (3) 446-450.
10.1016/j.ajhg.2011.08.001
InterAct Consortium, Langenberg C, Sharp S, Forouhi NG, Franks PW, Schulze MB, Kerrison N, Ekelund U et al.(2011). Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. Diabetologia vol. 54, (9) 2272-2282.
10.1007/s00125-011-2182-9
Butterworth AS, Braund PS, Farrall M, Hardwick RJ, Saleheen D, Peden JF, Soranzo N, Chambers JC et al.(2011). Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genetics vol. 7, (9)
10.1371/journal.pgen.1002260
Suhre K, Shin S-Y, Petersen A-K, Mohney RP, Meredith D, Wägele B, Altmaier E, CARDIoGRAM et al.(2011). Human metabolic individuality in biomedical and pharmaceutical research. Nature vol. 477, (7362) 54-60.
10.1038/nature10354
Sawcer S, Hellenthal G, Pirinen M, Spencer CCA, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z et al.(2011). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. NATURE vol. 476, (7359) 214-219.
10.1038/nature10251
Kilpeläinen TO, Zillikens MC, Stan¿ákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS et al.(2011). Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genetics vol. 43, (8) 753-760.
10.1038/ng.866
Evans DM, Spencer CCA, Pointon JJ, Su Z, Harvey D, Kochan G, Opperman U, Dilthey A et al.(2011). Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. NAT GENET vol. 43, (8) 761-U67.
10.1038/ng.873
Stathopoulou MG, Dedoussis GVZ, Trovas G, Theodoraki EV, Katsalira A, Dontas IA, Hammond N, Deloukas P et al.(2011). The role of vitamin D receptor gene polymorphisms in the bone mineral density of Greek postmenopausal women with low calcium intake. J Nutr Biochem vol. 22, (8) 752-757.
10.1016/j.jnutbio.2010.06.007
Wildman RP, Kaplan R, Manson JE, Rajkovic A, Connelly SA, MacKey RH, Tinker LF, Curb JD et al.(2011). Body size phenotypes and inflammation in the women's health initiative observational study. Obesity vol. 19, (7) 1482-1491.
10.1038/oby.2010.332
Rajpathak SN, Kaplan RC, Wassertheil-Smoller S, Cushman M, Rohan TE, McGinn AP, Wang T, Strickler HD et al.(2011). Resistin, but not adiponectin and leptin, is associated with the risk of ischemic stroke among postmenopausal women: Results from the women's health initiative. Stroke vol. 42, (7) 1813-1820.
10.1161/STROKEAHA.110.607853
Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Parrinello CM et al.(2011). T cell activation predicts carotid artery stiffness among HIV-infected women. Atherosclerosis vol. 217, (1) 207-213.
10.1016/j.atherosclerosis.2011.03.011
Plagnol V, Nalls MA, Bras JM, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simon-Sanchez J et al.(2011). A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease. PLOS GENET vol. 7, (6) Article e1002142,
10.1371/journal.pgen.1002142
Barker A, Sharp SJ, Timpson NJ, Bouatia-Naji N, Warrington NM, Kanoni S, Beilin LJ, Brage S et al.(2011). Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children. Diabetes vol. 60, (6) 1805-1812.
10.2337/db10-1575
Dedoussis GVZ, Yannakoulia M, Timpson NJ, Manios Y, Kanoni S, Scott RA, Papoutsakis C, Deloukas P et al.(2011). Does a short breastfeeding period protect from FTO-induced adiposity in children?. Int J Pediatr Obes vol. 6, (2-2) e326-e335.
10.3109/17477166.2010.490269
Small KS, Hedman AK, Grundberg E, Nica AC, Thorleifsson G, Kong A, Thorsteindottir U, Shin S-Y et al.(2011). Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat Genet vol. 43, (6) 561-564.
10.1038/ng.833
Paul DS, Nisbet JP, Yang T-P, Meacham S, Rendon A, Hautaviita K, Tallila J, White J et al.(2011). Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits. PLoS Genet vol. 7, (6)
10.1371/journal.pgen.1002139
Obeidat M, Wain LV, Shrine N, Kalsheker N, Artigas MS, Repapi E, Burton PR, Johnson T et al.(2011). A Comprehensive Evaluation of Potential Lung Function Associated Genes in the SpiroMeta General Population Sample. PLOS ONE vol. 6, (5) Article e19382,
10.1371/journal.pone.0019382
Wang T, Rohan TE, Gunter MJ, Xue X, Wactawski-Wende J, Rajpathak SN, Cushman M, Strickler HD et al.(2011). A prospective study of inflammation markers and endometrial cancer risk in postmenopausal hormone nonusers. Cancer Epidemiology Biomarkers and Prevention vol. 20, (5) 971-977.
10.1158/1055-9965.EPI-10-1222
Hollingworth P, Harold D, Sims R, Gerrish A, Lambert J-C, Carrasquillo MM, Abraham R, Hamshere ML et al.(2011). Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. NATURE GENETICS vol. 43, (5) 429-+.
10.1038/ng.803
Panoutsopoulou K, Southam L, Elliott KS, Wrayner N, Zhai G, Beazley C, Thorleifsson G, Arden NK et al.(2011). Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Ann Rheum Dis vol. 70, (5) 864-867.
10.1136/ard.2010.141473
Southam L, Panoutsopoulou K, Rayner NW, Chapman K, Durrant C, Ferreira T, Arden N, Carr A et al.(2011). The effect of genome-wide association scan quality control on imputation outcome for common variants. Eur J Hum Genet vol. 19, (5) 610-614.
10.1038/ejhg.2010.242
Frank RAW, McRae AF, Pocklington AJ, van de Lagemaat LN, Navarro P, Croning MDR, Komiyama NH, Bradley SJ et al.(2011). Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder. PLoS One vol. 6, (4)
10.1371/journal.pone.0019011
Glass D, Parts L, Knowles D, Nica AC, Nisbet J, Barrett A, Sekowska M, Travers M et al. (2011). Biomarkers of skin ageing using genome wide transcriptomics. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 931-931.
Peden JF, Hopewell JC, Saleheen D, Chambers JC, Hager J, Soranzo N, Collins R, Danesh J et al.(2011). A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. NAT GENET vol. 43, (4) 339-U89.
10.1038/ng.782
Glass D, Parts L, Knowles D, Nica AC, Nisbet J, Barrett A, Sekowska M, Travers M et al. (2011). Biomarkers of skin ageing using genome wide transcriptomics. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 131, S66-S66.
Kilpeläinen TO, Den Hoed M, Ong KK, Grøntved A, Brage S, Jameson K, Cooper C, Khaw KT et al.(2011). Obesity-susceptibility loci have a limited influence on birth weight: A meta-analysis of up to 28,219 individuals. American Journal of Clinical Nutrition vol. 93, (4) 851-860.
10.3945/ajcn.110.000828
McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, Kasperavi¿i¿t¿ D, Carrington M, Sills GJ, Marson T et al.(2011). HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. N Engl J Med vol. 364, (12) 1134-1143.
10.1056/NEJMoa1013297
Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AFR et al.(2011). Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet vol. 43, (4) 333-338.
10.1038/ng.784
Kaplan RC, Petersen AK, Chen MH, Teumer A, Glazer NL, DÖring A, Lam CSP, Friedrich N et al.(2011). A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. Human Molecular Genetics vol. 20, (6) 1241-1251.
10.1093/hmg/ddq560
Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C et al.(2011). Common variants at 10 genomic loci influence hemoglobin A<inf>1C</inf> levels via glycemic and nonglycemic pathways (Diabetes (2010) 59, (3229-3239)). Diabetes vol. 60, (3)
Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G et al.(2011). Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genetics vol. 7, (3)
10.1371/journal.pgen.1001324
Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simon-Sanchez J, Schulte C et al.(2011). Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. LANCET vol. 377, (9766) 641-649.
10.1016/S0140-6736(10)62345-8
Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt P et al.(2011). T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women. Journal of Infectious Diseases vol. 203, (4) 452-463.
10.1093/infdis/jiq071
Nica AC, Parts L, Glass D, Nisbet J, Barrett A, Sekowska M, Travers M, Potter S et al.(2011). The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet vol. 7, (2)
10.1371/journal.pgen.1002003
Zhou KX, Bellenguez C, Spencer CCA, Bennett AJ, Coleman RL, Tavendale R, Hawley SA, Donnelly LA et al.(2011). Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. NAT GENET vol. 43, (2) 117-U57.
10.1038/ng.735
Evangelou E, Valdes AM, Kerkhof HJM, Styrkarsdottir U, Zhu Y, Meulenbelt I, Lories RJ, Karassa FB et al.(2011). Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis vol. 70, (2) 349-355.
10.1136/ard.2010.132787
Spencer CCA, Plagnol V, Strange A, Gardner M, Paisan-Ruiz C, Band G, Barker RA, Bellenguez C et al.(2011). Dissection of the genetics of Parkinson's disease identifies an additional association 5 ' of SNCA and multiple associated haplotypes at 17q21. HUM MOL GENET vol. 20, (2) 345-353.
10.1093/hmg/ddq469
Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y et al.(2011). A genome-wide association study of aging. Neurobiology of Aging vol. 32, (11) 2109.e15-2109.e28.
10.1016/j.neurobiolaging.2011.05.026
Campino S, Auburn S, Kivinen K, Zongo I, Ouedraogo J-B, Mangano V, Djimde A, Doumbo OK et al.(2011). Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. PLoS One vol. 6, (6)
10.1371/journal.pone.0020251
Herder C, Peeters W, Illig T, Baumert J, de Kleijn DPV, Moll FL, Poschen U, Klopp N et al.(2011). RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies. PLoS One vol. 6, (12)
10.1371/journal.pone.0025734
Clark MD, Guryev V, Bruijn ED, Nijman IJ, Tada M, Wilson C, Deloukas P, Postlethwait JH et al.(2011). Single nucleotide polymorphism (SNP) panels for rapid positional cloning in zebrafish. Methods Cell Biol vol. 104, 219-235.
10.1016/B978-0-12-374814-0.00013-6
Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C et al.(2010). Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes vol. 59, (12) 3229-3239.
10.2337/db10-0502
Elks CE, Perry JRB, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA et al.(2010). Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet vol. 42, (12) 1077-1085.
10.1038/ng.714
Hopewell JC, Peden J, Saleheen D, Chambers J, Clarke R, Collins R, Danesh J, Deloukas P et al. (2010). A Genome-Wide Association Study of Risk of Coronary Artery Disease in European and South Asian Populations. CIRCULATION. vol. 122,
Paternoster L, Lorentzon M, Vandenput L, Karlsson MK, Ljunggren O, Kindmark A, Mellstrom D, Kemp JP et al.(2010). Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone. PLoS Genet vol. 6, (11)
10.1371/journal.pgen.1001217
Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R et al.(2010). Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One vol. 5, (11)
10.1371/journal.pone.0013950
Combarros O, Warden DR, Hammond N, Cortina-Borja M, Belbin O, Lehmann MG, Wilcock GK, Brown K et al.(2010). The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project. BMC Med Genet vol. 11,
10.1186/1471-2350-11-162
Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, Erdmann J, Willenborg C et al.(2010). Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol vol. 56, (19) 1552-1563.
10.1016/j.jacc.2010.06.022
Strange A, Capon F, Spencer CCA, Knight J, Weale ME, Allen MH, Barton A, Band G et al.(2010). A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. NAT GENET vol. 42, (11) 985-U106.
10.1038/ng.694
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM et al.(2010). Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet vol. 42, (11) 937-948.
10.1038/ng.686
Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W et al.(2010). Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol vol. 30, (11) 2264-2276.
10.1161/ATVBAHA.109.201020
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC et al.(2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet vol. 42, (11) 949-960.
10.1038/ng.685
Allen HL, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU et al.(2010). Hundreds of variants clustered in genomic loci and biological pathways affect human height. NATURE vol. 467, (7317) 832-838.
10.1038/nature09410
Seaberg EC, Benning L, Sharrett AR, Lazar JM, Hodis HN, MacK WJ, Siedner MJ, Phair JP et al.(2010). Association between human immunodeficiency virus infection and stiffness of the common carotid artery. Stroke vol. 41, (10) 2163-2170.
10.1161/STROKEAHA.110.583856
Yang T-P, Beazley C, Montgomery SB, Dimas AS, Gutierrez-Arcelus M, Stranger BE, Deloukas P, Dermitzakis ET(2010). Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies. Bioinformatics vol. 26, (19) 2474-2476.
10.1093/bioinformatics/btq452
Panoutsopoulou K, Southam L, Rayner W, Zhai G, Beazley C, Arden N, Carr A, Chapman K et al. (2010). THE arcOGEN CONSORTIUM: STAGE 1 OF A GENOME-WIDE ASSOCIATION SCAN FOR OSTEOARTHRITIS. OSTEOARTHRITIS AND CARTILAGE. vol. 18, S166-S167.
10.1016/S1063-4584(10)60405-0
Heinig M, Petretto E, Wallace C, Bottolo L, Rotival M, Lu H, Li Y, Sarwar R et al.(2010). A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature vol. 467, (7314) 460-464.
10.1038/nature09386
International HapMap 3 Consortium, Altshuler DM, Gibbs RA, Peltonen L, Altshuler DM, Gibbs RA, Peltonen L, Dermitzakis E et al.(2010). Integrating common and rare genetic variation in diverse human populations. Nature vol. 467, (7311) 52-58.
10.1038/nature09298
Pagnamenta AT, Bacchelli E, de Jonge MV, Mirza G, Scerri TS, Minopoli F, Chiocchetti A, Ludwig KU et al.(2010). Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry vol. 68, (4) 320-328.
10.1016/j.biopsych.2010.02.002
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S et al.(2010). Biological, clinical and population relevance of 95 loci for blood lipids. NATURE vol. 466, (7307) 707-713.
10.1038/nature09270
Alfirevic A, Bourgeois S, Jorgensen A, Steen K, Weetman D, Park BK, Deloukas P, Pirmohamed M (2010). Carbamazepine-induced hypersensitivity in Caucasians and genetic variability in the major histocompatibility complex. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 70, 298-298.
Sorlie PD, Avilés-Santa LM, Wassertheil-Smoller S, Kaplan RC, Daviglus ML, Giachello AL, Schneiderman N, Raij L et al.(2010). Design and Implementation of the Hispanic Community Health Study/Study of Latinos. Annals of Epidemiology vol. 20, (8) 629-641.
10.1016/j.annepidem.2010.03.015
Hilner JE, Perdue LH, Sides EG, Pierce JJ, Wägner AM, Aldrich A, Loth A, Albret L et al.(2010). Designing and implementing sample and data collection for an international genetics study: The Type 1 Diabetes Genetics Consortium (T1DGC). Clinical Trials vol. 7, (1_suppl) S5-S32.
10.1177/1740774510373497
Saleheen D, Soranzo N, Rasheed A, Scharnagl H, Gwilliam R, Alexander M, Inouye M, Zaidi M et al.(2010). Genetic determinants of major blood lipids in Pakistanis compared with Europeans. Circ Cardiovasc Genet vol. 3, (4) 348-357.
10.1161/CIRCGENETICS.109.906180
LaVange LM, Kalsbeek WD, Sorlie PD, Avilés-Santa LM, Kaplan RC, Barnhart J, Liu K, Giachello A et al.(2010). Sample Design and Cohort Selection in the Hispanic Community Health Study/Study of Latinos. Annals of Epidemiology vol. 20, (8) 642-649.
10.1016/j.annepidem.2010.05.006
Palella FJ, Gange SJ, Benning L, Jacobson L, Kaplan RC, Landay AL, Tracy RP, Elion R(2010). Inflammatory biomarkers and abacavir use in the women's Interagency HIV study and the multicenter AIDS cohort study. AIDS vol. 24, (11) 1657-1665.
10.1097/QAD.0b013e3283389dfa
Saleheen D, Alexander M, Rasheed A, Wormser D, Soranzo N, Hammond N, Butterworth A, Zaidi M et al.(2010). Association of the 9p21.3 locus with risk of first-ever myocardial infarction in Pakistanis: case-control study in South Asia and updated meta-analysis of Europeans. Arterioscler Thromb Vasc Biol vol. 30, (7) 1467-1473.
10.1161/ATVBAHA.109.197210
Stathopoulou MG, Dedoussis GVZ, Trovas G, Katsalira A, Hammond N, Deloukas P, Lyritis GP(2010). Low-density lipoprotein receptor-related protein 5 polymorphisms are associated with bone mineral density in Greek postmenopausal women: an interaction with calcium intake. J Am Diet Assoc vol. 110, (7) 1078-1083.
10.1016/j.jada.2010.04.007
Turnbull C, Rapley EA, Seal S, Pernet D, Renwick A, Hughes D, Ricketts M, Linger R et al.(2010). Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer. Nat Genet vol. 42, (7) 604-607.
10.1038/ng.607
McGinnis RE, Deloukas P, McLaren WM, Inouye M(2010). Visualizing chromosome mosaicism and detecting ethnic outliers by the method of "rare" heterozygotes and homozygotes (RHH). Hum Mol Genet vol. 19, (13) 2539-2553.
10.1093/hmg/ddq102
Hamberg A-K, Wadelius M, Lindh JD, Dahl ML, Padrini R, Deloukas P, Rane A, Jonsson EN(2010). A pharmacometric model describing the relationship between warfarin dose and INR response with respect to variations in CYP2C9, VKORC1, and age. Clin Pharmacol Ther vol. 87, (6) 727-734.
10.1038/clpt.2010.37
Rajpathak SN, Gupta LS, Waddell EN, Upadhyay UD, Wildman RP, Kaplan R, Wassertheil-Smoller S, Wylie-Rosett J(2010). Elevated risk of type 2 diabetes and metabolic syndrome among Asians and South Asians: Results from the 2004 New York City HANES. Ethnicity and Disease vol. 20, (3) 225-230.
Ritchie ME, Forrest MS, Dimas AS, Daelemans C, Dermitzakis ET, Deloukas P, Tavaré S(2010). Data analysis issues for allele-specific expression using Illumina's GoldenGate assay. BMC Bioinformatics vol. 11,
10.1186/1471-2105-11-280
Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T et al.(2010). A Meta-analysis of four genome-wide association studies of survival to age 90 years or older: The cohorts for heart and aging research in genomic epidemiology consortium. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 65 A, (5) 478-487.
10.1093/gerona/glq028
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GAR et al.(2010). Erratum: Multiple common variants for celiac disease influencing immune gene expression (Nature Genetics DOI: 10.1038/ng.543). Nature Genetics vol. 42, (5)
10.1038/ng0510-465
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL et al.(2010). Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116)). Nature Genetics vol. 42, (5)
10.1038/ng0510-464a
Rajpathak SN, Wang T, Wassertheil-Smoller S, Strickler HD, Kaplan RC, McGinn AP, Wildman RP, Rosenbaum D et al.(2010). Hepatocyte growth factor and the risk of ischemic stroke developing among postmenopausal women: Results from the women's health initiative. Stroke vol. 41, (5) 857-862.
10.1161/STROKEAHA.109.567719
Lenzini P, Wadelius M, Kimmel S, Anderson JL, Jorgensen AL, Pirmohamed M, Caldwell MD, Limdi N et al.(2010). Integration of genetic, clinical, and INR data to refine warfarin dosing. Clin Pharmacol Ther vol. 87, (5) 572-578.
10.1038/clpt.2010.13
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GAR et al.(2010). Multiple common variants for celiac disease influencing immune gene expression (vol 42, pg 295, 2010). NATURE GENETICS vol. 42, (5) 465-465.
10.1038/ng0510-465
Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E et al.(2010). Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet vol. 42, (5) 430-435.
10.1038/ng.567
International Stroke Genetics Consortium, Wellcome Trust Case-Control Consortium 2(2010). Failure to validate association between 12p13 variants and ischemic stroke. N Engl J Med vol. 362, (16) 1547-1550.
10.1056/NEJMc0910050
Daelemans C, Ritchie ME, Smits G, Abu-Amero S, Sudbery IM, Forrest MS, Campino S, Clark TG et al.(2010). High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta. BMC Genet vol. 11,
10.1186/1471-2156-11-25
Medland SE, Zayats T, Glaser B, Nyholt DR, Gordon SD, Wright MJ, Montgomery GW, Campbell MJ et al.(2010). A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. Am J Hum Genet vol. 86, (4) 519-525.
10.1016/j.ajhg.2010.02.017
Paul DS, Soranzo N, Ouwehand WH, Deloukas P (2010). Elucidating the chromatin architecture of loci associated with blood traits and coronary artery disease. NEW BIOTECHNOLOGY. vol. 27, S64-S64.
10.1016/j.nbt.2010.01.184
Craddock N, Hurles ME, Cardin N, Pearson RD, Plagnol V, Robson S, Vukcevic D, Barnes C et al.(2010). Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. NATURE vol. 464, (7289) 713-U86.
10.1038/nature08979
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14895
Rakyan VK, Down TA, Maslau S, Andrew T, Yang T-P, Beyan H, Whittaker P, McCann OT et al.(2010). Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains. Genome Res vol. 20, (4) 434-439.
10.1101/gr.103101.109
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GAR et al.(2010). Multiple common variants for celiac disease influencing immune gene expression. Nat Genet vol. 42, (4) 295-302.
10.1038/ng.543
Louie L, Pathanapornpandh N, Pultajuk U, Kaplan R, Hodgson I, Maund L, Greenlee H(2010). The Mae On Project: Using acupuncture for symptom relief and improved quality of life for people living with HIV and AIDS in rural Thailand. Acupuncture in Medicine vol. 28, (1) 37-41.
10.1136/aim.2008.000299
Pillas D, Hoggart CJ, Evans DM, O'Reilly PF, Sipilä K, Lähdesmäki R, Millwood IY, Kaakinen M et al.(2010). Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. PLoS Genet vol. 6, (2)
10.1371/journal.pgen.1000856
Bignell GR, Greenman CD, Davies H, Butler AP, Edkins S, Andrews JM, Buck G, Chen L et al.(2010). Signatures of mutation and selection in the cancer genome. Nature vol. 463, (7283) 893-898.
10.1038/nature08768
Australo-Anglo-American Spondyloarthritis Consortium (TASC), Reveille JD, Sims A-M, Danoy P, Evans DM, Leo P, Pointon JJ, Jin R et al.(2010). Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet vol. 42, (2) 123-127.
10.1038/ng.513
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL et al.(2010). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. NAT GENET vol. 42, (2) 105-U32.
10.1038/ng.520
Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A et al.(2010). Genome-wide association study identifies five loci associated with lung function. NAT GENET vol. 42, (1) 36-U51.
10.1038/ng.501
Bell CG, Finer S, Lindgren CM, Wilson GA, Rakyan VK, Teschendoff AE, Akan P, Stupka E et al.(2010). Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus. PLOS One
10.1371/journal.pone.0014040
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14550
Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Matthijs Boekholdt S, Ouwehand W, Watkins H et al.(2010). Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studies. The Lancet vol. 375, (9726) 1634-1639.
10.1016/S0140-6736(10)60545-4
Glesby MJ, Hoover DR, Raiszadeh F, Lee I, Shi Q, Milne G, Sanchez SC, Gao W et al.(2009). Oxidant stress in HIV-infected women from the Women's Interagency HIV Study. Antiviral Therapy vol. 14, (6) 763-769.
10.3851/IMP1290
Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJF, Perry JRB, Tanaka T, Timpson NJ et al.(2009). A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels. PLOS GENET vol. 5, (12) Article e1000768,
10.1371/journal.pgen.1000768
Barrett JC, Lee JC, Lees CW, Prescott NJ, Anderson CA, Phillips A, Wesley E, Parnell K et al.(2009). Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. NAT GENET vol. 41, (12) 1330-U99.
10.1038/ng.483
Kaplan RC, Fitzpatrick AL, Pollak MN, Gardner JP, Jenny NS, McGinn AP, Kuller LH, Strickler HD et al.(2009). Insulin-like growth factors and leukocyte telomere length: The cardiovascular health study. Journals of Gerontology - Series A Biological Sciences and Medical Sciences vol. 64, (11) 1103-1106.
10.1093/gerona/glp036
McGinnis R, Deloukas P, McLaren W, Inouye M (2009). Visualizing Chromosome Mosaicism and Detecting Ethnic Outliers by the Method of "Rare" Heterozygotes and Homozygotes (RHH). GENETIC EPIDEMIOLOGY. vol. 33, 756-756.
Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B et al.(2009). A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet vol. 41, (11) 1182-1190.
10.1038/ng.467
Ganesh SK, Zakai NA, van Rooij FJA, Soranzo N, Smith AV, Nalls MA, Chen M-H, Kottgen A et al.(2009). Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet vol. 41, (11) 1191-1198.
10.1038/ng.466
Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu Y-H, Richards JB, Zillikens MC, Kavvoura FK et al.(2009). Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet vol. 41, (11) 1199-1206.
10.1038/ng.446
Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu Y-H, Zillikens MC et al.(2009). Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med vol. 151, (8) 528-537.
10.7326/0003-4819-151-8-200910200-00006
Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, Lee MTM, Limdi NA, Page D et al.(2009). Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data (vol 360, pg 753, 2009). NEW ENGLAND JOURNAL OF MEDICINE vol. 361, (16) 1613-1613.
Mansoor A, Althoff K, Gange S, Anastos K, Dehovitz J, Minkoff H, Kaplan R, Holman S et al.(2009). Elevated NT-pro-BNP levels are associated with comorbidities among HIV-infected women. AIDS Research and Human Retroviruses vol. 25, (10) 997-1004.
10.1089/aid.2009.0038
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V et al.(2009). Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics) (2009) 41 (1088-1093)). Nature Genetics vol. 41, (10)
10.1038/ng1009-1156d
Jorgensen AL, Al-Zubiedi S, Zhang JE, Keniry A, Hanson A, Hughes DA, Eker DV, Stevens L et al.(2009). Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study. Pharmacogenet Genomics vol. 19, (10) 800-812.
10.1097/FPC.0b013e3283317ab5
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V et al.(2009). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet vol. 41, (10) 1088-1093.
10.1038/ng.440
Dimas AS, Deutsch S, Stranger BE, Montgomery SB, Borel C, Attar-Cohen H, Ingle C, Beazley C et al.(2009). Common regulatory variation impacts gene expression in a cell type-dependent manner. Science vol. 325, (5945) 1246-1250.
10.1126/science.1174148
Zucker S, Schmidt CE, Dufour A, Kaplan RC, Park HI, Jiang W(2009). ProMMP-2: TIMP-1 complexes identified in plasma of healthy individuals. Connective Tissue Research vol. 50, (4) 223-231.
10.1080/03008200802626970
Zhai G, van Meurs JBJ, Livshits G, Meulenbelt I, Valdes AM, Soranzo N, Hart D, Zhang F et al.(2009). A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium. J Med Genet vol. 46, (9) 614-616.
10.1136/jmg.2009.067314
Daelemans C, Ritchie ME, Abu-Amero S, Sudbery IM, Stanier P, Forrest MS, Deloukas P, Tavare S et al. (2009). Assessment of candidate imprinted genes in the human term placenta. JOURNAL OF MEDICAL GENETICS. vol. 46, S88-S88.
Tien PC, Schneider MF, Cole SR, Cohen MH, Glesby MJ, Lazar J, Young M, MacK W et al.(2009). Association of hepatitis C virus and HIV infection with subclinical atherosclerosis in the women's interagency HIV study. AIDS vol. 23, (13) 1781-1784.
10.1097/QAD.0b013e32832d7aa8
Combarros O, van Duijn CM, Hammond N, Belbin O, Arias-Vásquez A, Cortina-Borja M, Lehmann MG, Aulchenko YS et al.(2009). Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease. J Neuroinflammation vol. 6,
10.1186/1742-2094-6-22
Jones CI, Bray S, Garner SF, Stephens J, de Bono B, Angenent WGJ, Bentley D, Burns P et al.(2009). A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood vol. 114, (7) 1405-1416.
10.1182/blood-2009-02-202614
Falchi M, Bataille V, Hayward NK, Duffy DL, Bishop JAN, Pastinen T, Cervino A, Zhao ZZ et al.(2009). Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet vol. 41, (8) 915-919.
10.1038/ng.410
Nolte IM, Wallace C, Newhouse SJ, Waggott D, Fu J, Soranzo N, Gwilliam R, Deloukas P et al.(2009). Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. PLoS One vol. 4, (7)
10.1371/journal.pone.0006138
Mangino M, Richards JB, Soranzo N, Zhai G, Aviv A, Valdes AM, Samani NJ, Deloukas P et al.(2009). A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length. J Med Genet vol. 46, (7) 451-454.
10.1136/jmg.2008.064956
Rapley EA, Turnbull C, Al Olama AA, Dermitzakis ET, Linger R, Huddart RA, Renwick A, Hughes D et al.(2009). A genome-wide association study of testicular germ cell tumor. Nat Genet vol. 41, (7) 807-810.
10.1038/ng.394
Prokopenko I, Zeggini E, Hanson RL, Mitchell BD, Rayner NW, Akan P, Baier L, Das SK et al.(2009). Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q. Diabetes vol. 58, (7) 1704-1709.
10.2337/db09-0081
Rajpathak SN, Gunter MJ, Wylie-Rosett J, Ho GYF, Kaplan RC, Muzumdar R, Rohan TE, Strickler HD(2009). The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetes. Diabetes/Metabolism Research and Reviews vol. 25, (1) 3-12.
10.1002/dmrr.919
Richards J, Kavvoura FK, Rivadeneira F, Styrkarsdottir U, Estrada K, Halldorsson B, Hsu Y, Zillikens M et al. (2009). A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data. BONE. vol. 44, S222-S223.
10.1016/j.bone.2009.03.068
Ong KK, Elks CE, Li S, Zhao JH, Luan J, Andersen LB, Bingham SA, Brage S et al.(2009). Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet vol. 41, (6) 729-733.
10.1038/ng.382
Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G et al.(2009). Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution. PLOS GENET vol. 5, (6) Article e1000508,
10.1371/journal.pgen.1000508
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19181
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH et al.(2009). Genome-wide association study identifies eight loci associated with blood pressure. NAT GENET vol. 41, (6) 666-676.
10.1038/ng.361
Stolk L, Zhai G, van Meurs JBJ, Verbiest MMPJ, Visser JA, Estrada K, Rivadeneira F, Williams FM et al.(2009). Loci at chromosomes 13, 19 and 20 influence age at natural menopause. Nat Genet vol. 41, (6) 645-647.
10.1038/ng.387
Heard-Costa NL, Carola Zillikens M, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF et al.(2009). NRXN3Is a novel locus for waist circumference: A genome-wide association study from the CHARGE consortium. PLoS Genetics vol. 5, (6)
10.1371/journal.pgen.1000539
Raiszadeh F, Hoover DR, Lee I, Shi Q, Anastos K, Gao W, Kaplan RC, Glesby MJ(2009). Plasma homocysteine is not associated with HIV serostatus or antiretroviral therapy in women. Journal of Acquired Immune Deficiency Syndromes vol. 51, (2) 175-178.
10.1097/QAI.0b013e3181a42bdf
Rivadeneira F, Styrkarsdottir U, Estrada K, Halldorsson B, Hsu Y, Richards JB, Zillikens MC, Kavvoura F et al. (2009). Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets. BONE. vol. 44, S230-S231.
10.1016/j.bone.2009.03.085
WALTON RT(2009). Genome-wide and fine-resolution association analysis of malaria in West Africa. Nature Genetics vol. 41, (6) 675-665.
10.1038/ng.388
Dubois PC, Trynka G, Heap GA, Hunt KA, Franke L, van Heel D, Gwilliam R, Deloukas P et al. (2009). Copy Number Variant and Extended SNP Genome Wide Association Study in Celiac Disease. GASTROENTEROLOGY. vol. 136, A263-A263.
Coronary Artery Disease Consortium, Samani NJ, Deloukas P, Erdmann J, Hengstenberg C, Kuulasmaa K, McGinnis R, Schunkert H et al.(2009). Large scale association analysis of novel genetic loci for coronary artery disease. Arterioscler Thromb Vasc Biol vol. 29, (5) 774-780.
10.1161/ATVBAHA.108.181388
Mansoor A, Golub ET, Dehovitz J, Anastos K, Kaplan RC, Lazar JM(2009). The association of HIV infection with left ventricular mass/hypertrophy. AIDS Research and Human Retroviruses vol. 25, (5) 475-481.
10.1089/aid.2008.0170
Soranzo N, Rendon A, Gieger C, Jones CI, Watkins NA, Menzel S, Döring A, Stephens J et al.(2009). A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function. Blood vol. 113, (16) 3831-3837.
10.1182/blood-2008-10-184234
Timpson NJ, Tobias JH, Richards JB, Soranzo N, Duncan EL, Sims A-M, Whittaker P, Kumanduri V et al.(2009). Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Hum Mol Genet vol. 18, (8) 1510-1517.
10.1093/hmg/ddp052
Daelemans C, Ritchie M, Abu-Amero S, Sudbery IM, Stanier P, Forrest MS, Deloukas P, Tavare S et al. (2009). Assessment of candidate imprinted genes in the human term placenta. GENETICS RESEARCH. vol. 91, 136-136.
Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB, Hammond N, Stolk L, Nica A et al.(2009). Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet vol. 5, (4)
10.1371/journal.pgen.1000445
Bonaglia MC, Giorda R, Beri S, Bigoni S, Sensi A, Baroncini A, Capucci A, De Agostini C et al.(2009). Mosaic 22q13 deletions: evidence for concurrent mosaic segmental isodisomy and gene conversion. Eur J Hum Genet vol. 17, (4) 426-433.
10.1038/ejhg.2008.195
Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V et al.(2009). A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet vol. 5, (3)
10.1371/journal.pgen.1000433
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19449
Myocardial Infarction Genetics Consortium, Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, Anand S et al.(2009). Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet vol. 41, (3) 334-341.
10.1038/ng.327
Erdmann J, Grosshennig A, Braund PS, König IR, Hengstenberg C, Hall AS, Linsel-Nitschke P, Kathiresan S et al.(2009). New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet vol. 41, (3) 280-282.
10.1038/ng.307
International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, Lee M-TM, Limdi NA et al.(2009). Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med vol. 360, (8) 753-764.
10.1056/NEJMoa0809329
Yngvadottir B, Xue Y, Searle S, Hunt S, Delgado M, Morrison J, Whittaker P, Deloukas P et al.(2009). A genome-wide survey of the prevalence and evolutionary forces acting on human nonsense SNPs. Am J Hum Genet vol. 84, (2) 224-234.
10.1016/j.ajhg.2009.01.008
McGinnis R, McLaren W, Ranganath V, Whittaker P, Hunt S, Deloukas P, Type 1 Diabetes Genetics Consortium(2009). Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype. Diabetes Obes Metab vol. 11 Suppl 1, 8-16.
10.1111/j.1463-1326.2008.00998.x
Anderson CA, Massey DCO, Barrett JC, Prescott NJ, Tremelling M, Fisher SA, Gwilliam R, Jacob J et al.(2009). Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology vol. 136, (2) 523-9.e3.
10.1053/j.gastro.2008.10.032
Brown WM, Pierce J, Hilner JE, Perdue LH, Lohman K, Li L, Venkatesh RB, Hunt S et al.(2009). Overview of the MHC fine mapping data. Diabetes Obes Metab vol. 11 Suppl 1, 2-7.
10.1111/j.1463-1326.2008.00997.x
Wadelius M, Chen LY, Lindh JD, Eriksson N, Ghori MJR, Bumpstead S, Holm L, McGinnis R et al.(2009). The largest prospective warfarin-treated cohort supports genetic forecasting. Blood vol. 113, (4) 784-792.
10.1182/blood-2008-04-149070
Meisinger C, Prokisch H, Gieger C, Soranzo N, Mehta D, Rosskopf D, Lichtner P, Klopp N et al.(2009). A genome-wide association study identifies three loci associated with mean platelet volume. Am J Hum Genet vol. 84, (1) 66-71.
10.1016/j.ajhg.2008.11.015
Akan P, Sahlén M, Deloukas P(2009). A histone map of human chromosome 20q13.12. PLoS One vol. 4, (2)
10.1371/journal.pone.0004479
Gunter MJ, Hoover DR, Yu H, Wassertheil-Smoller S, Rohan TE, Manson JE, Li J, Ho GYF et al.(2009). Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal women. Journal of the National Cancer Institute vol. 101, (1) 48-60.
10.1093/jnci/djn415
Willer CJ, Speliotes EK, Loos RJF, Li SX, Lindgren CM, Heid IM, Berndt SI, Elliott AL et al.(2009). Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. NAT GENET vol. 41, (1) 25-34.
10.1038/ng.287
Saleheen D, Zaidi M, Rasheed A, Ahmad U, Hakeem A, Murtaza M, Kayani W, Faruqui A et al.(2009). The Pakistan Risk of Myocardial Infarction Study: a resource for the study of genetic, lifestyle and other determinants of myocardial infarction in South Asia. Eur J Epidemiol vol. 24, (6) 329-338.
10.1007/s10654-009-9334-y
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJF, Manning AK et al.(2009). Variants in MTNR1B influence fasting glucose levels. NAT GENET vol. 41, (1) 77-81.
10.1038/ng.290
Achidi EA, Agbenyega T, Allen S, Amodu O, Bojang K, Conway D, Corran P, Deloukas P et al.(2008). A global network for investigating the genomic epidemiology of malaria. Nature vol. 456, (7223) 732-737.
10.1038/nature07632
Soranzo N, Tussen MR, Rendon A, Meisinger C, Jones CI, Gieger C, Watkins NA, Menzel S et al. (2008). A Common Single Nucleotide Polymorphism in the Chromosome 7q22.3 Region, Which Is Frequently Deleted in Myeloid Malignancies, Is Associated with Mean Platelet Volume and Platelet Function in Healthy Individuals. BLOOD. vol. 112, 39-39.
Garner SF, Jones CI, Stephens J, Bray SL, Angenent W, Burns P, Farndale RW, Rice C et al. (2008). Functional Genomics of the Platelet ADP and Collagen Signalling Pathways. BLOOD. vol. 112, 648-648.
Savage DA, Patterson CC, Deloukas P, Whittaker P, McKnight AJ, Morrison J, Boulton AJ, Demaine AG et al.(2008). Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy. Diabetologia vol. 51, (11) 1998-2002.
10.1007/s00125-008-1142-5
Kaplan RC, McGinn AP, Baird AE, Hendrix SL, Kooperberg C, Lynch J, Rosenbaum DM, Johnson KC et al.(2008). Inflammation and Hemostasis Biomarkers for Predicting Stroke in Postmenopausal Women: The Women's Health Initiative Observational Study. Journal of Stroke and Cerebrovascular Diseases vol. 17, (6) 344-355.
10.1016/j.jstrokecerebrovasdis.2008.04.006
Richards JB, Yuan X, Geller F, Waterworth D, Bataille V, Glass D, Song K, Waeber G et al.(2008). Male-pattern baldness susceptibility locus at 20p11. Nat Genet vol. 40, (11) 1282-1284.
10.1038/ng.255
Kaplan RC, Smith NL, Zucker S, Heckbert SR, Rice K, Psaty BM(2008). Matrix metalloproteinase-3 (MMP3) and MMP9 genes and risk of myocardial infarction, ischemic stroke, and hemorrhagic stroke. Atherosclerosis vol. 201, (1) 130-137.
10.1016/j.atherosclerosis.2008.01.003
Barroso I, Luan JA, Wheeler E, Whittaker P, Wasson J, Zeggini E, Weedon MN, Hunt S et al.(2008). Population-Specific Risk of Type 2 Diabetes Conferred by HAT4A P2 Promoter Variants A Lesson for Replication Studies. DIABETES vol. 57, (11) 3161-3165.
10.2337/db08-0719
Thomas MC, Dublin S, Kaplan RC, Glazer NL, Lumley T, Longstreth WT, Smith NL, Psaty BM et al.(2008). Blood pressure control and risk of incident atrial fibrillation. American Journal of Hypertension vol. 21, (10) 1111-1116.
10.1038/ajh.2008.248
Aneurysm Consortium(2008). Genome Wide Association Studies: identifying the genes that determine the risk of abdominal aortic aneurysm. Eur J Vasc Endovasc Surg vol. 36, (4) 395-396.
10.1016/j.ejvs.2008.06.003
Liu Y-Z, Wilson SG, Wang L, Liu X-G, Guo Y-F, Li J, Yan H, Deloukas P et al. (2008). Identification of PLCL1 Gene for Hip Bone Size Variation in Females in a Genomewide Association Study. JOURNAL OF WOMENS HEALTH. vol. 17, 1254-1254.
Dimas AS, Stranger BE, Beazley C, Finn RD, Ingle CE, Forrest MS, Ritchie ME, Deloukas P et al.(2008). Modifier effects between regulatory and protein-coding variation. PLoS Genet vol. 4, (10)
10.1371/journal.pgen.1000244
Liu Y-Z, Wilson SG, Wang L, Liu X-G, Guo Y-F, Li J, Yan H, Deloukas P et al.(2008). Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS One vol. 3, (9)
10.1371/journal.pone.0003160
Franke L, de Kovel CGF, Aulchenko YS, Trynka G, Zhernakova A, Heap G, Blauw HM, van den Berg LH et al. (2008). Detection, imputation and association analysis of small deletions and null-alleles on oligonucleotide arrays. ANNALS OF HUMAN GENETICS. vol. 72, 687-687.
Morris A, Prokopenko I, Akan P, Lango H, Zeggini E, Frayling TM, Deloukas P, Hattersley AT et al. (2008). Fine-mapping type 2 diabetes causal variants on chromosome 9p21 in 2000 UK cases and 3000 unselected controls. DIABETOLOGIA. vol. 51, S125-S125.
Richards J, Rivadeneira F, Inouye M, Pastinen T, Soranzo N, Wilson SG, Andrew T, Falchi M et al. (2008). Genome-Wide Association Study Reveals Genetic Variants Associated with Bone Mineral Density, Osteoporosis and Osteoporotic Fractures. JOURNAL OF BONE AND MINERAL RESEARCH. vol. 23, S184-S184.
Miretti M, Galanti L, Minichello M, Venkatesh R, Whittaker P, Kallon D, Durbin R, Hurles M et al. (2008). Haplotype-specific recombination shapes the genealogy of ancestral European haplotypes. TISSUE ANTIGENS. vol. 72, 234-234.
Kaplan RC, Kingsley LA, Gange SJ, Benning L, Jacobson LP, Lazar J, Anastos K, Tien PC et al.(2008). Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men. AIDS vol. 22, (13) 1615-1624.
10.1097/QAD.0b013e328300581d
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS et al.(2008). Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet vol. 40, (8) 955-962.
10.1038/ng.175
Stein JH, Hadigan CM, Brown TT, Chadwick E, Feinberg J, Friis-Møller N, Ganesan A, Glesby MJ et al. (2008). Prevention Strategies for Cardiovascular Disease in HIV-infected Patients. Circulation. vol. 118,
10.1161/CIRCULATIONAHA.107.189628
Samani NJ, Goetz A, Braund P, McGinnis R, Tregouet D-A, Mangino M, Linsel-Nitschke P, Cambien F et al. (2008). Repeated replication and meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. HEART. vol. 94, A15-A15.
Loos RJF, Lindgren CM, Li SX, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM et al.(2008). Common variants near MC4R are associated with fat mass, weight and risk of obesity. NAT GENET vol. 40, (6) 768-775.
10.1038/ng.140
Franke L, de Kovel CGF, Aulchenko YS, Trynka G, Zhernakova A, Hunt KA, Blauw HM, van den Berg LH et al.(2008). Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays. Am J Hum Genet vol. 82, (6) 1316-1333.
10.1016/j.ajhg.2008.05.008
Morris A, Prokopenko I, Akan P, Lango H, Frayling TM, Deloukas P, Hattersley AT, McCarthy MI (2008). Fine-mapping T2D causal variants on chromosome 9p21 in 2000 UK cases and 3000 unselected controls. DIABETES. vol. 57, A326-A326.
Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, Prescott NJ, Nimmo ER, Massey D et al.(2008). Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet vol. 40, (6) 710-712.
10.1038/ng.145
Kaplan RC, McGinn AP, Pollak MN, Kuller L, Strickler HD, Rohan TE, Cappola AR, Xue XN et al.(2008). High insulinlike growth factor binding protein 1 level predicts incident congestive heart failure in the elderly. American Heart Journal vol. 155, (6) 1006-1012.
10.1016/j.ahj.2007.12.031
Ouwehand WH, Watkins N, Deloukas P, Samani N, Goodall A (2008). PL V: Platelet systems biology meets genome-wide association study; the discovery of genes implicated in atherothrombosis. Pathophysiology of Haemostasis and Thrombosis. vol. 36,
Deloukas P (2008). The era of genome wide scans - applications in pharmacogenomics. FEBS JOURNAL. vol. 275, 11-11.
Richards JB, Rivadeneira F, Inouye M, Pastinen TM, Soranzo N, Wilson SG, Andrew T, Falchi M et al.(2008). Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Lancet vol. 371, (9623) 1505-1512.
10.1016/S0140-6736(08)60599-1
Weedon MN, Lango H, Lindgren CM, Wallace C, Evans DM, Mangino M, Freathy RM, Perry JRB et al.(2008). Genome-wide association analysis identifies 20 loci that influence adult height. NAT GENET vol. 40, (5) 575-583.
10.1038/ng.121
Baker S, Holt K, van de Vosse E, Roumagnac P, Whitehead S, King E, Ewels P, Keniry A et al.(2008). High-throughput genotyping of Salmonella enterica serovar Typhi allowing geographical assignment of haplotypes and pathotypes within an urban District of Jakarta, Indonesia. J Clin Microbiol vol. 46, (5) 1741-1746.
10.1128/JCM.02249-07
Hunt KA, Franke L, Deloukas P, Wjmenga C, Van Heel DA(2008). No evidence in a large UK collection for celiac disease risk variants reported by a Spanish study. GASTROENTEROLOGY vol. 134, (5) 1629-1630.
10.1053/j.gastro.2008.03.068
Gunter MJ, Hoover DR, Yu H, Wassertheil-Smoller S, Manson JE, Li J, Harris TG, Rohan TE et al.(2008). A prospective evaluation of insulin and insulin-like growth factor-I as risk factors for endometrial cancer. Cancer Epidemiology Biomarkers and Prevention vol. 17, (4) 921-929.
10.1158/1055-9965.EPI-07-2686
Rajpathak SN, McGinn AP, Strickler HD, Rohan TE, Pollak M, Cappola AR, Kuller L, Xue XN et al.(2008). Insulin-like growth factor-(IGF)-axis, inflammation, and glucose intolerance among older adults. Growth Hormone and IGF Research vol. 18, (2) 166-173.
10.1016/j.ghir.2007.08.004
Wassertheil-Smoller S, Kooperberg C, McGinn AP, Kaplan RC, Hsia J, Hendrix SL, Manson JAE, Berger JS et al.(2008). Lipoprotein-associated phospholipase A2, hormone use, and the risk of ischemic stroke in postmenopausal women. Hypertension vol. 51, (4 PART 2 SUPPL.) 1115-1122.
10.1161/HYPERTENSIONAHA.107.103721
Hunt KA, Zhernakova A, Turner G, Heap GAR, Franke L, Bruinenberg M, Romanos J, Dinesen LC et al.(2008). Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet vol. 40, (4) 395-402.
10.1038/ng.102
https://qmro.qmul.ac.uk/xmlui/handle/123456789/3282
Schunkert H, Götz A, Braund P, McGinnis R, Tregouet D-A, Mangino M, Linsel-Nitschke P, Cambien F et al.(2008). Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation vol. 117, (13) 1675-1684.
10.1161/CIRCULATIONAHA.107.730614
Kaplan RC, McGinn AP, Pollak MN, Kuller L, Strickler HD, Rohan TE, Xue XN, Kritchevsky SB et al.(2008). Total insulinlike growth factor 1 and insulinlike growth factor binding protein levels, functional status, and mortality in older adults. Journal of the American Geriatrics Society vol. 56, (4) 652-660.
10.1111/j.1532-5415.2007.01637.x
McGinn AP, Kaplan RC, Verghese J, Rosenbaum DM, Psaty BM, Baird AE, Lynch JK, Wolf PA et al.(2008). Walking speed and risk of incident ischemic stroke among postmenopausal women. Stroke vol. 39, (4) 1233-1239.
10.1161/STROKEAHA.107.500850
Teo YY, Inouye M, Small KS, Fry AE, Potter SC, Dunstan SJ, Seielstad M, Barroso I et al.(2008). Whole genome-amplified DNA: insights and imputation. Nat Methods vol. 5, (4) 279-280.
10.1038/nmeth0408-279
Robertson N, Javed N, Samani NJ, Khunti K(2008). Psychological morbidity and illness appraisals of patients with cardiac and non-cardiac chest pain attending a rapid access chest pain clinic: a longitudinal cohort study. Heart vol. 94, (3)
10.1136/hrt.2006.100537
Akan P, Deloukas P(2008). DNA sequence and structural properties as predictors of human and mouse promoters. Gene vol. 410, (1) 165-176.
10.1016/j.gene.2007.12.011
Sandhu MS, Waterworth DM, Debenham SL, Wheeler E, Papadakis K, Zhao JH, Song KJ, Yuan X et al.(2008). LDL-cholesterol concentrations: a genome-wide association study. LANCET vol. 371, (9611) 483-491.
10.1016/S0140-6736(08)60208-1
Strickler HD, Fazzari M, Kovacs A, Isasi C, Napolitano LA, Minkoff H, Gange S, Young M et al.(2008). Associations of insulin-like growth factor (IGF)-I and IGF-binding protein-3 with HIV disease progression in women. Journal of Infectious Diseases vol. 197, (2) 319-327.
10.1086/524848
Wallace C, Newhouse SJ, Braund P, Zhang F, Tobin M, Falchi M, Ahmadi K, Dobson RJ et al.(2008). Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet vol. 82, (1) 139-149.
10.1016/j.ajhg.2007.11.001
Gunter MJ, Hoover DR, Yu H, Wassertheil-Smoller S, Rohan TE, Manson JE, Howard BV, Wylie-Rosett J et al.(2008). Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women. Cancer Research vol. 68, (1) 329-337.
10.1158/0008-5472.CAN-07-2946
Harris TG, Burk RD, Yu H, Minkoff H, Massad LS, Watts DH, Zhong Y, Gange S et al.(2008). Insulin-like growth factor axis and oncogenic human papillomavirus natural history. Cancer Epidemiology Biomarkers and Prevention vol. 17, (1) 245-248.
10.1158/1055-9965.EPI-07-0686
Nejentsev S, Howson JMM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M et al.(2007). Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature vol. 450, (7171) 887-892.
10.1038/nature06406
Thomson W, Barton A, Ke X, Eyre S, Hinks A, Bowes J, Donn R, Symmons D et al.(2007). Rheumatoid arthritis association at 6q23. Nature Genetics vol. 39, (12) 1431-1433.
10.1038/ng.2007.32
Wallace C, Newhouse SJ, Braund P, Zhang F, Tobin M, Falchi M, Ahmadi K, Dobson RJ et al. (2007). Discovery of novel genes for serum urate and low-density lipoprotein cholesterol - Two biomarkers of cardiovascular disease. CIRCULATION RESEARCH. vol. 101, 1208-1208.
Newport M, Sirugo G, Lyons E, Vannberg F, Hill AVS, Bradbury LA, Farrar C, Pointon JJ et al.(2007). Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. NAT GENET vol. 39, (11) 1329-1337.
10.1038/ng.2007.17
Wellcome Trust Case Control Consortium, Australo-Anglo-American Spondylitis Consortium (TASC), Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A et al.(2007). Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet vol. 39, (11) 1329-1337.
10.1038/ng.2007.17
Kaplan RC, Kingsley LA, Sharrett AR, Li X, Lazar J, Tien PC, Mack WJ, Cohen MH et al.(2007). Ten-year predicted coronary heart disease risk in HIV-infected men and women. Clinical Infectious Diseases vol. 45, (8) 1074-1081.
10.1086/521935
International HapMap Consortium, Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW et al.(2007). A second generation human haplotype map of over 3.1 million SNPs. Nature vol. 449, (7164) 851-861.
10.1038/nature06258
Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH et al.(2007). Genome-wide detection and characterization of positive selection in human populations. Nature vol. 449, (7164) 913-918.
10.1038/nature06250
Teo YY, Inouye M, Small KS, Gwilliam R, Deloukas P, Kwiatkowski DP, Clark TG(2007). A genotype calling algorithm for the Illumina BeadArray platform. Bioinformatics vol. 23, (20) 2741-2746.
10.1093/bioinformatics/btm443
Stranger BE, Nica AC, Forrest MS, Dimas A, Bird CP, Beazley C, Ingle CE, Dunning M et al.(2007). Population genomics of human gene expression. Nat Genet vol. 39, (10) 1217-1224.
10.1038/ng2142
Zhao JH, Li S, Luan JA, Tan Q, Wheeler E, Debenham S, Inouye M, Deloukas P et al. (2007). Continuous and discrete association analyses of body mass index and obesity. GENETIC EPIDEMIOLOGY. vol. 31, 652-652.
Prokopenko I, Zeggini E, Rayner NW, Groves CJ, Hanson RL, Mitchell BD, Vaxillaire M, Hunt SE et al. (2007). High-density association mapping and comprehensive tagging of the type 2 diabetes linkage region on chromosome 1q in 4 European populations. DIABETOLOGIA. vol. 50, S75-S75.
Kaplan RC, Tien PC, Lazar J(2007). Antiretroviral drugs and the risk of myocardial infarction [8]. New England Journal of Medicine vol. 357, (7) 715-717.
10.1056/NEJMc071419
Ribeiro L, Busnello JV, Cantor RM, Whelan F, Whittaker P, Deloukas P, Wong M-L, Licinio J(2007). The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans. Neuroreport vol. 18, (12) 1291-1293.
10.1097/WNR.0b013e328273bcb0
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T et al.(2007). Genomewide association analysis of coronary artery disease. NEW ENGLAND JOURNAL OF MEDICINE vol. 357, (5) 443-453.
10.1056/NEJMoa072366
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T et al.(2007). Genomewide association analysis of coronary artery disease. N Engl J Med vol. 357, (5) 443-453.
10.1056/NEJMoa072366
van de Garde EMW, Oosterheert JJ, Bonten M, Kaplan RC, Leufkens HGM(2007). International classification of diseases codes showed modest sensitivity for detecting community-acquired pneumonia. Journal of Clinical Epidemiology vol. 60, (8) 834-838.
10.1016/j.jclinepi.2006.10.018
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MCNM et al.(2007). A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. NAT GENET vol. 39, (7) 827-829.
10.1038/ng2058
Reveille JD, Zhou X, Bradbury LA, Cardon LR, Davis JC, Deloukas P, Evans DM, Keniry A et al. (2007). Il-23r is a major determinant of ankylosing spondylitis risk - The tasc study. ANNALS OF THE RHEUMATIC DISEASES. vol. 66, 112-112.
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER et al.(2007). Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet vol. 39, (7) 830-832.
10.1038/ng2061
WALLACE C, Wellcome Trust CCC(2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature vol. 447, (7145) 661-678.
10.1038/nature05911
Liskova P, Tuft SJ, Gwilliam R, Ebenezer ND, Jirsova K, Prescott Q, Martincova R, Pretorius M et al.(2007). Novel mutations in the ZEB1 gene identified in Czech and British patients with posterior polymorphous corneal dystrophy. Hum Mutat vol. 28, (6)
10.1002/humu.9495
Kaplan RC, Ho GYF, Xue XN, Rajpathak S, Cushman M, Rohan TE, Strickler HD, Scherer PE et al.(2007). Within-individual stability of obesity-related biomarkers among women. Cancer Epidemiology Biomarkers and Prevention vol. 16, (6) 1291-1293.
10.1158/1055-9965.EPI-06-1089
Nejentsev S, Smink LJ, Smyth D, Bailey R, Lowe CE, Payne F, Masters J, Godfrey L et al.(2007). Sequencing and association analysis of the type 1 diabetes-linked region on chromosome 10p12-q11. BMC Genet vol. 8,
10.1186/1471-2156-8-24
Anastos K, Lu D, Shi Q, Tien PC, Kaplan RC, Hessol NA, Cole S, Vigen C et al.(2007). Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens. Journal of Acquired Immune Deficiency Syndromes vol. 45, (1) 34-42.
10.1097/QAI.0b013e318042d5fe
Tremelling M, Cummings F, Fisher SA, Mansfield J, Gwilliam R, Keniry A, Nimmo ER, Drummond H et al.(2007). IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Gastroenterology vol. 132, (5) 1657-1664.
10.1053/j.gastro.2007.02.051
Wadelius M, Chen LY, Lindh J, Eriksson N, Holm L, Bumpstead S, Ghori J, Bentley DR et al. (2007). Warfarin dose associated with genes involved in its action and metabolism. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. vol. 37, 47-48.
Chu WS, Das SK, Wang H, Chan JC, Deloukas P, Froguel P, Baier LJ, Jia W et al.(2007). Activating transcription factor 6 (ATF6) sequence polymorphisms in type 2 diabetes and pre-diabetic traits. Diabetes vol. 56, (3) 856-862.
10.2337/db06-1305
Wadelius M, Chen LY, Eriksson N, Bumpstead S, Ghori J, Wadelius C, Bentley D, McGinnis R et al.(2007). Association of warfarin dose with genes involved in its action and metabolism. Hum Genet vol. 121, (1) 23-34.
10.1007/s00439-006-0260-8
Owen KR, Groves CJ, Hanson RL, Knowler WC, Shuldiner AR, Elbein SC, Mitchell BD, Froguel P et al.(2007). Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects. Diabetes vol. 56, (3) 879-883.
10.2337/db06-0930
Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, Thorne N, Redon R, Bird CP et al.(2007). Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science vol. 315, (5813) 848-853.
10.1126/science.1136678
Kaplan RC, McGinn AP, Pollak MN, Kuller LH, Strickler HD, Rohan TE, Cappola AR, Xue XN et al.(2007). Association of total insulin-like growth factor-I, insulin-like growth factor binding protein-1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke. Journal of Clinical Endocrinology and Metabolism vol. 92, (4) 1319-1325.
10.1210/jc.2006-1631
Tishkoff SA, Reed FA, Ranciaro A, Voight BF, Babbitt CC, Silverman JS, Powell K, Mortensen HM et al.(2007). Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet vol. 39, (1) 31-40.
10.1038/ng1946
Whittaker P, Bumpstead S, Downes K, Ghori J, Deloukas P(2006). Single Nucleotide Polymorphism Analysis by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Cell Biology, Four-Volume Set, vol. 3,
Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC et al.(2006). Erratum: The international type 2 diabetes 1q consortium: Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q (Diabetes (2006) 55 (2541-2548)). Diabetes vol. 55, (11)
10.2337/db06-er11
Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC et al.(2006). The International Type 2 Diabetes 1q Consortium: Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q. (vol 55, pg 2541, 2006). DIABETES vol. 55, (11) 3197-3197.
Wong M-L, Whelan F, Deloukas P, Whittaker P, Delgado M, Cantor RM, McCann SM, Licinio J(2006). Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response. Proc Natl Acad Sci U S A vol. 103, (41) 15124-15129.
10.1073/pnas.0602795103
de Bakker PIW, McVean G, Sabeti PC, Miretti MM, Green T, Marchini J, Ke X, Monsuur AJ et al.(2006). A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet vol. 38, (10) 1166-1172.
10.1038/ng1885
Spencer CCA, Deloukas P, Hunt S, Mullikin J, Myers S, Silverman B, Donnelly P, Bentley D et al.(2006). The influence of recombination on human genetic diversity. PLoS Genet vol. 2, (9)
10.1371/journal.pgen.0020148
Kaplan RC, Tirschwell DL, Longstreth WT, Manolio TA, Heckbert SR, LeValley AJ, Lefkowitz D, El-Saed A et al.(2006). Blood pressure level and outcomes in adults aged 65 and older with prior ischemic stroke. Journal of the American Geriatrics Society vol. 54, (9) 1309-1316.
10.1111/j.1532-5415.2006.00838.x
Das SK, Chu WS, Hale TC, Wang X, Craig RL, Wang H, Shuldiner AR, Froguel P et al.(2006). Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes. Diabetes vol. 55, (9) 2631-2639.
10.2337/db05-1369
Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC et al.(2006). Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q. Diabetes vol. 55, (9) 2541-2548.
10.2337/db06-0088
Ayerdi-Izquierdo A, Stavrides G, Sellés-Martínez JJ, Larrea L, Bovo G, López de Munain A, Bisulli F, Martí-Massó JF et al.(2006). Genetic analysis of the LGI/Epitempin gene family in sporadic and familial lateral temporal lobe epilepsy. Epilepsy Res vol. 70, (2-3) 118-126.
10.1016/j.eplepsyres.2006.03.008
Zeggini E, Rayner W, Hanson R, Groves C, Mitchell B, O'Connell J, Vaxillaire M, Jia W et al. (2006). Large-scale association studies to identify diabetes-susceptibility loci on chromosome 1q: The importance of stringent quality control. DIABETES. vol. 55, A267-A267.
Zeggini E, Rayner W, Groves C, Hanson R, Mitchell B, O'Connell J, Vaxillaire M, Jia W et al. (2006). Replicated association between type 2 diabetes and variants in CAPON revealed by high density linkage disequilibrium mapping on chromosome 1q. DIABETES. vol. 55, A83-A83.
Rayner W, Zeggini E, Hanson R, Mitchell B, Groves C, O'Connell J, Vaxillaire M, Jia W et al. (2006). Variation in the retinoid X receptor gamma gene is associated with type 2 diabetes in sample sets displaying linkage to chromosome 1q. DIABETES. vol. 55, A263-A264.
Harris TG, Strickler HD, Yu H, Pollak MN, Monrad ES, Travin MI, Xue X, Rohan TE et al.(2006). Specimen processing time and measurement of total insulin-like growth factor-I (IGF-I), free IGF-I, and IGF binding protein-3 (IGFBP-3). Growth Hormone and IGF Research vol. 16, (2) 86-92.
10.1016/j.ghir.2006.01.002
González-Neira A, Ke X, Lao O, Calafell F, Navarro A, Comas D, Cann H, Bumpstead S et al.(2006). The portability of tagSNPs across populations: a worldwide survey. Genome Res vol. 16, (3) 323-330.
10.1101/gr.4138406
Kaplan RC, Tirschwell DL, Longstreth WT(2006). Erratum: Vascular events, mortality, and preventive therapy following ischemic stroke in the elderly (Neurology (2005) 65 (835-842)). Neurology vol. 66, (4)
10.1212/01.wnl.0000202600.72018.39
Kaplan RC, Bhalodkar NC, Brown DL, White J, Brown EJ(2006). Differences by age and race/ethnicity in knowledge about hypercholesterolemia. Cardiology in Review vol. 14, (1) 1-6.
10.1097/01.crd.0000160308.62033.29
Ho GYF, Qian H, Kim MY, Melnik TA, Tucker KL, Jimenez-Velazquez IZ, Kaplan RC, Lee-Rey ET et al.(2006). Health disparities between island and mainland Puerto Ricans. Revista Panamericana de Salud Publica/Pan American Journal of Public Health vol. 19, (5) 331-339.
10.1590/S1020-49892006000500006
Zeggini E, Rayner W, Morris AP, Hattersley AT, Walker M, Hitman GA, Deloukas P, Cardon LR et al.(2005). An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets. Nat Genet vol. 37, (12) 1320-1322.
10.1038/ng1670
Stranger BE, Forrest MS, Clark AG, Minichiello MJ, Deutsch S, Lyle R, Hunt S, Kahl B et al.(2005). Genome-wide associations of gene expression variation in humans. PLoS Genet vol. 1, (6)
10.1371/journal.pgen.0010078
Gwilliam R, Liskova P, Filipec M, Kmoch S, Jirsova K, Huckle EJ, Stables CL, Bhattacharya SS et al.(2005). Posterior polymorphous corneal dystrophy in Czech families maps to chromosome 20 and excludes the VSX1 gene. Invest Ophthalmol Vis Sci vol. 46, (12) 4480-4484.
10.1167/iovs.05-0269
Chen LY, Eriksson N, Gwilliam R, Bentley D, Deloukas P, Wadelius M(2005). Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing. Blood vol. 106, (10) 3673-3674.
10.1182/blood-2005-04-1711
Lawrence R, Evans DM, Morris AP, Ke X, Hunt S, Paolucci M, Ragoussis J, Deloukas P et al.(2005). Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants. Genome Res vol. 15, (11) 1503-1510.
10.1101/gr.4217605
Belmont JW, Boudreau A, Leal SM, Hardenbol P, Pasternak S, Wheeler DA, Willis TD, Yu F et al.(2005). A haplotype map of the human genome. Nature vol. 437, (7063) 1299-1320.
10.1038/nature04226
Kaplan RC, Tirschwell DL, Longstreth WT, Manolio TA, Heckbert SR, Lefkowitz D, El-Saed A, Psaty BM(2005). Vascular events, mortality, and preventive therapy following ischemic stroke in the elderly. Neurology vol. 65, (6) 835-842.
10.1212/01.wnl.0000176058.09848.bb
Ke X, Miretti MM, Broxholme J, Hunt S, Beck S, Bentley DR, Deloukas P, Cardon LR(2005). A comparison of tagging methods and their tagging space. Hum Mol Genet vol. 14, (18) 2757-2767.
10.1093/hmg/ddi309
Tyler-Smith C, Xue Y, Daly A, Gillson C, Yngvadottir B, Liu M, Searle S, Hunt S et al. (2005). Evolution by gene loss in humans. JOURNAL OF MEDICAL GENETICS. vol. 42, S35-S35.
Hitte C, Madeoy J, Kirkness EF, Priat C, Lorentzen TD, Senger F, Thomas D, Derrien T et al.(2005). Facilitating genome navigation: survey sequencing and dense radiation-hybrid gene mapping. Nat Rev Genet vol. 6, (8) 643-648.
10.1038/nrg1658
Ho GYF, Xue XN, Burk RD, Kaplan RC, Cornell E, Cushman M(2005). Variability of serum levels of tumor necrosis factor-alpha, interleukin 6, and soluble interleukin 6 receptor over 2 years in young women. Cytokine vol. 30, (1) 1-6.
10.1016/j.cyto.2004.08.008
Miretti MM, Walsh EC, Ke X, Delgado M, Griffiths M, Hunt S, Morrison J, Whittaker P et al.(2005). A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet vol. 76, (4) 634-646.
10.1086/429393
Kaplan RC, Schechter C(2005). Cost implications of new evidence on prevention of cardiovascular disease. Expert Review of Pharmacoeconomics and Outcomes Research vol. 5, (2) 183-192.
10.1586/14737167.5.2.183
Rayner W, Zeggini E, Groves CJ, Mitchell BD, Sabra MM, Hanson RL, Vaxillaire M, Jia WP et al. (2005). Bioinformatic-based positional candidate selection on chromosome 1q and large-scale association analysis. DIABETES. vol. 54, A33-A34.
Wadelius M, Chen LY, Downes K, Ghori J, Hunt S, Eriksson N, Wallerman O, Melhus H et al.(2005). Common VKORC1 and GGCX polymorphisms associated with warfarin dose. Pharmacogenomics J vol. 5, (4) 262-270.
10.1038/sj.tpj.6500313
McCarthy MI, Zeggini E, Groves CJ, Rayner W, Hanson RL, Damcott C, O'Connell JR, Vaxillaire M et al. (2005). Dense-map, large-scale analysis indicates that variation within the CRP gene does not associate with diabetes in chromosome 1q-linked populations. DIABETES. vol. 54, A277-A277.
Kaplan RC, Strickler HD, Rohan TE, Muzumdar R, Brown DL(2005). Insulin-like growth factors and coronary heart disease. Cardiology in Review vol. 13, (1) 35-39.
10.1097/01.crd.0000134914.10407.40
Zeggini E, Rayner W, Groves CJ, Hanson RL, Mitchell BD, O'Connell J, Vaxillaire M, Froguel P et al. (2005). Linkage disequilibrium mapping of the type 2 diabetes susceptibility variants on chromosome Iq in European populations. DIABETOLOGIA. vol. 48, A128-A128.
Zeggini E, Rayner W, Groves CJ, Hanson RL, Mitchell BD, O'Connell JF, Vaxillaire M, Jia WP et al. (2005). Meta-analysis of 3000 single nucleotide polymorphisms from chromosome 1q in samples from seven linked populations reveals shared type 2 diabetes susceptibility variants. DIABETES. vol. 54, A33-A33.
Rayner W, Zeggini E, Groves CJ, Wiltshire S, Hunt S, Whittaker P, Delgado M, Morrison J et al. (2005). Positional candidate gene selection on chromosome 1q using bioinformatics and large scale association analysis. DIABETOLOGIA. vol. 48, A108-A108.
McCarthy MI, Zeggini E, Rayner W, Groves CJ, Hanson RL, Damcott C, Pollin TI, Vaxillaire M et al. (2005). Variation within the hyperlipidaemia susceptibility gene, USF1, does not explain 1q-encoded susceptibility to type 2 diabetes. DIABETES. vol. 54, A34-A34.
Zhang W, Collins A, Gibson J, Tapper WJ, Hunt S, Deloukas P, Bentley DR, Morton NE(2004). Impact of population structure, effective bottleneck time, and allele frequency on linkage disequilibrium maps. Proc Natl Acad Sci U S A vol. 101, (52) 18075-18080.
10.1073/pnas.0408251102
Bench AJ, Li J, Huntly BJP, Delabesse E, Fourouclas N, Hunt AR, Deloukas P, Green AR(2004). Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tumour suppressor gene, in patients with myeloid malignancies. Br J Haematol vol. 127, (5) 509-518.
10.1111/j.1365-2141.2004.05278.x
Kaplan RC, Bhalodkar NC, Brown EJ, White J, Brown DL(2004). Race, ethnicity, and sociocultural characteristics predict noncompliance with lipid-lowering medications. Preventive Medicine vol. 39, (6) 1249-1255.
10.1016/j.ypmed.2004.04.041
Ke X, Durrant C, Morris AP, Hunt S, Bentley DR, Deloukas P, Cardon LR(2004). Efficiency and consistency of haplotype tagging of dense SNP maps in multiple samples. Hum Mol Genet vol. 13, (21) 2557-2565.
10.1093/hmg/ddh294
International Human Genome Sequencing Consortium(2004). Finishing the euchromatic sequence of the human genome. Nature vol. 431, (7011) 931-945.
10.1038/nature03001
Sarafidou T, Kahl C, Martinez-Garay I, Mangelsdorf M, Gesk S, Baker E, Kokkinaki M, Talley P et al.(2004). Folate-sensitive fragile site FRA10A is due to an expansion of a CGG repeat in a novel gene, FRA10AC1, encoding a nuclear protein. Genomics vol. 84, (1) 69-81.
10.1016/j.ygeno.2003.12.017
Durrant C, Zondervan KT, Cardon LR, Hunt S, Deloukas P, Morris AP(2004). Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. Am J Hum Genet vol. 75, (1) 35-43.
10.1086/422174
International HapMap Consortium(2004). Integrating ethics and science in the International HapMap Project. Nat Rev Genet vol. 5, (6) 467-475.
10.1038/nrg1351
Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L, Steward CA, Sims SK, Jones MC et al.(2004). The DNA sequence and comparative analysis of human chromosome 10. NATURE vol. 429, (6990) 375-381.
10.1038/nature02462
Downes K, Barratt BJ, Akan P, Bumpstead SJ, Taylor SD, Clayton DG, Deloukas P(2004). SNP allele frequency estimation in DNA pools and variance components analysis. Biotechniques vol. 36, (5) 840-845.
10.2144/04365RR01
Travin MI, Heller GV, Johnson LL, Katten D, Ahlberg AW, Isasi CR, Kaplan RC, Taub CC et al.(2004). The prognostic value of ECG-gated SPECT imaging in patients undergoing stress Tc-99m sestamibi myocardial perfusion imaging. Journal of Nuclear Cardiology vol. 11, (3) 253-262.
10.1016/j.nuclcard.2004.02.005
McVean GAT, Myers SR, Hunt S, Deloukas P, Bentley DR, Donnelly P(2004). The fine-scale structure of recombination rate variation in the human genome. Science vol. 304, (5670) 581-584.
10.1126/science.1092500
Silander K, Mohlke KL, Scott LJ, Peck EC, Hollstein P, Skol AD, Jackson AU, Deloukas P et al.(2004). Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes vol. 53, (4) 1141-1149.
10.2337/diabetes.53.4.1141
Bench AJ, Li J, Huntly BJP, Vassiliou GS, Delabesse E, Fourouclas N, Hunt AR, Deloukas P et al. (2004). L3MBTL, a candidate 20q tumour suppressor gene is not mutated in patients with myeloid malignancies and displays monoallelic methylation. BRITISH JOURNAL OF HAEMATOLOGY. vol. 125, 15-15.
Dunham A, Matthews LH, Burton J, Ashurst JL, Howe KL, Ashcroft KJ, Beare DM, Burford DC et al.(2004). The DNA sequence and analysis of human chromosome 13. Nature vol. 428, (6982) 522-528.
10.1038/nature02379
Ke X, Hunt S, Tapper W, Lawrence R, Stavrides G, Ghori J, Whittaker P, Collins A et al.(2004). The impact of SNP density on fine-scale patterns of linkage disequilibrium. Hum Mol Genet vol. 13, (6) 577-588.
10.1093/hmg/ddh060
Deloukas P, Bentley D(2004). The HapMap project and its application to genetic studies of drug response. Pharmacogenomics J vol. 4, (2) 88-90.
10.1038/sj.tpj.6500226
Belmont JW, Hardenbol P, Willis TD, Yu F, Yang H, Ch'Ang LY, Huang W, Liu B et al.(2003). The international HapMap project. Nature vol. 426, (6968) 789-796.
10.1038/nature02168
Morris A, Durrant C, Zondervan K, Hunt S, Deloukas P, Cardon L (2003). Linkage disequilibrium mapping via cladistic analysis of SNP haplotypes. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 73, 613-613.
Cardon LR, Ke X, Lawrence R, Carter N, Rogers J, Stavrides G, Willey D, Mullikin J et al. (2003). Towards a fine-scale linkage disequilibrium map of human chromosome 20. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 73, 216-216.
Smith NL, Lemaitre RN, Heckbert SR, Kaplan RC, Tirschwell DL, Longstreth WT, Psaty BM(2003). Serum potassium and stroke risk among treated hypertensive adults. American Journal of Hypertension vol. 16, (10) 806-813.
10.1016/S0895-7061(03)00983-X
Vakili BA, Kaplan RC, Slater JN, Sherman W, Ravi KL, Green SJ, Sanborn TA, Brown DL(2003). A propensity analysis of the impact of platelet glycoprotein IIb/IIIa inhibitor therapy on in-hospital outcomes after percutaneous coronary intervention. American Journal of Cardiology vol. 91, (8) 946-950.
10.1016/S0002-9149(03)00109-7
Spriggs HF, Holmes NG, Breen M, Deloukas P, Langford CF, Ross MT, Carter NP, Davis ME et al.(2003). Construction and integration of radiation-hybrid and cytogenetic maps of dog chromosome X. Mammalian Genome vol. 14, (3) 214-221.
10.1007/s00335-002-3051-0
Green BB, Kaplan RC, Psaty BM(2003). How do minor changes in the definition of blood pressure control affect the reported success of hypertension treatment?. American Journal of Managed Care vol. 9, (3) 219-224.
Guy J, Hearn T, Crosier M, Mudge J, Viggiano L, Koczan D, Thiesen H-J, Bailey JA et al.(2003). Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. Genome Res vol. 13, (2) 159-172.
10.1101/gr.644503
Wilson SR, Vakili BA, Kaplan RC, Sherman W, Ravi KL, Sanborn TA, Brown DL(2003). Effect of diabetes mellitus on long-term survival following contemporary percutaneous coronary intervention. Kardiologia vol. 12, (2) 56-63.
Fang J, Wylie-Rosett J, Cohen HW, Kaplan RC, Alderman MH(2003). Exercise, body mass index, caloric intake, and cardiovascular mortality. American Journal of Preventive Medicine vol. 25, (4) 283-289.
10.1016/S0749-3797(03)00207-1
Fan JB, Oliphant A, Shen R, Kermani BG, Garcia F, Gunderson KL, Hansen M, Steemers F et al.(2003). Highly parallel SNP genotyping. Cold Spring Harb Symp Quant Biol vol. 68, 69-78.
10.1101/sqb.2003.68.69
Arora R, Ferrick KJ, Nakata T, Kaplan RC, Rozengarten M, Latif F, Ng K, Marcano V et al.(2003). I-123 MIBG imaging and heart rate variability analysis to predict the need for an implantable cardioverter defribillator. Journal of Nuclear Cardiology vol. 10, (2) 121-131.
10.1067/mnc.2003.2
Lemaitre RN, Heckbert SR, Psaty BM, Smith NL, Kaplan RC, Longstreth WT(2002). Hormone replacement therapy and associated risk of stroke in postmenopausal women. Archives of Internal Medicine vol. 162, (17) 1954-1960.
10.1001/archinte.162.17.1954
Rea TD, Heckbert SR, Kaplan RC, Smith NL, Lemaitre RN, Psaty BM(2002). Smoking status and risk for recurrent coronary events after myocardial infarction. Annals of Internal Medicine vol. 137, (6) 494-500.
10.7326/0003-4819-137-6-200209170-00009
Staub E, Pérez-Tur J, Siebert R, Nobile C, Moschonas NK, Deloukas P, Hinzmann B(2002). The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders. Trends Biochem Sci vol. 27, (9) 441-444.
10.1016/s0968-0004(02)02163-1
Dawson E, Abecasis GR, Bumpstead S, Chen Y, Hunt S, Beare DM, Pabial J, Dibling T et al.(2002). A first-generation linkage disequilibrium map of human chromosome 22. Nature vol. 418, (6897) 544-548.
10.1038/nature00864
Berliner JI, Rybicki AC, Kaplan RC, Monrad E, Freeman R, Billett HH(2002). Elevated levels of Factor XI are associated with cardiovascular disease in women. Thrombosis Research vol. 107, (1-2) 55-60.
10.1016/S0049-3848(02)00190-1
Kaplan RC, Heckbert SR, Koepsell TD, Rosendaal FR, Furberg CD, Cooper LS, Psaty BM(2002). Calcium channel blocker use and gastrointestinal tract bleeding among older adults [1]. Age and Ageing vol. 31, (3) 217-218.
10.1093/ageing/31.3.217
Gesk S, Kahl C, Harder L, French L, Earthrowl M, Martin-Subero JI, Schlegelberger B, Oscier DG et al. (2002). Genetic changes of chromosomal region 10q24 in malignant lymphomas: Detection of aberrations affecting the NFKB2/LYT10 gene locus by FISH. EUROPEAN JOURNAL OF HUMAN GENETICS. vol. 10, 98-99.
Morante-Redolat JM, Gorostidi-Pagola A, Piquer-Sirerol S, Sáenz A, Poza JJ, Galán J, Gesk S, Sarafidou T et al.(2002). Mutations in the LGI1/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy. Hum Mol Genet vol. 11, (9) 1119-1128.
10.1093/hmg/11.9.1119
Gwilliam R, Ebenezer ND, Coggill PC, Bhattacharya SS, Deloukas P (2002). Transcript mapping and identification of candidate genes in the 3cM region of chromosome 20p 11.2 spanning the CHED1 locus. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. vol. 43, U809-U809.
Nobile C, Hinzmann B, Scannapieco P, Siebert R, Zimbello R, Perez-Tur J, Sarafidou T, Moschonas NK et al.(2002). Identification and characterization of a novel human brain-specific gene, homologous to S. scrofa tmp83.5, in the chromosome 10q24 critical region for temporal lobe epilepsy and spastic paraplegia. Gene vol. 282, (1-2) 87-94.
10.1016/s0378-1119(01)00846-0
Kaplan RC, Heckbert SR, Furberg CD, Psaty BM(2002). Predictors of subsequent coronary events, stroke, and death among survivors of first hospitalized myocardial infarction. Journal of Clinical Epidemiology vol. 55, (7) 654-664.
10.1016/S0895-4356(02)00405-5
Kaplan RC, Heckbert SR, Psaty BM(2002). Risk factors for hospitalized upper or lower gastrointestinal tract bleeding in treated hypertensives. Preventive Medicine vol. 34, (4) 455-462.
10.1006/pmed.2002.1008
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP et al.(2001). The DNA sequence and comparative analysis of human chromosome 20. Nature vol. 414, (6866) 865-871.
10.1038/414865a
Vakili BA, Kaplan RC, Brown DL(2001). Sex-based differences in early mortality of patients undergoing primary angioplasty for first acute myocardial infarction. Circulation vol. 104, (25) 3034-3038.
10.1161/hc5001.101060
Vakili BA, Kaplan R, Brown DL(2001). Volume-outcome relation for physicians and hospitals performing angioplasty for acute myocardial infarction in New York state. Circulation vol. 104, (18) 2171-2176.
10.1161/hc3901.096668
Cardon LR, Abecasis G, Dawson E, Bumpstead S, Chen Y, Hunt S, Pabiol J, Dibling T et al. (2001). A linkage disequilibrium map of chromosome 22. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 69, 197-197.
Deloukas P (2001). The sequence of human chromosome 20 and its comparative analysis. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 69, 219-219.
Fournier A, Oprisiu R, Michel Achard J, Klungel OH, Leufkens HGM, De Boer A, Longstreth WT, Kaplan RC et al.(2001). Differences between primary vs secondary prevention trials regarding the stroke protective effect of antihypertensive drugs [3] (multiple letters). Archives of Internal Medicine vol. 161, (17) 2152-2153.
10.1001/archinte.161.17.2152
Rea TD, Heckbert SR, Kaplan RC, Psaty BM, Smith NL, Lemaitre RN, Lin D(2001). Body mass index and the risk of recurrent coronary events following acute myocardial infarction. American Journal of Cardiology vol. 88, (5) 467-472.
10.1016/S0002-9149(01)01720-9
Kahl C, Gesk S, Harder L, Harbott J, French L, Deloukas P, Grote W, Schlegelberger B et al.(2001). Detection of translocations involving the HOX11/TCL3-locus in 10q24 by interphase fluorescence in situ hybridization. Cancer Genet Cytogenet vol. 129, (1) 80-84.
10.1016/s0165-4608(01)00426-5
Thomas R, Breen M, Deloukas P, Holmes NG, Binns MM(2001). An integrated cytogenetic, radiation-hybrid, and comparative map of dog chromosome 5. Mamm Genome vol. 12, (5) 371-375.
10.1007/s003350010287
Kaplan RC, Heckbert SR, Koepsell TD, Furberg CD, Polak JF, Schoen RE, Psaty BM(2001). Risk factors for hospitalized gastrointestinal bleeding among older persons. Journal of the American Geriatrics Society vol. 49, (2) 126-133.
10.1046/j.1532-5415.2001.49032.x
Yu A, Zhao C, Fan Y, Jang W, Mungall AJ, Deloukas P, Olsen A, Doggett NA et al.(2001). Comparison of human genetic and sequence-based physical maps. Nature vol. 409, (6822) 951-953.
10.1038/35057185
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K et al.(2001). Initial sequencing and analysis of the human genome. NATURE vol. 409, (6822) 860-921.
10.1038/35057062
Bentley DR, Deloukas P, Dunham A, French L, Gregory SG, Humphray SJ, Mungall AJ, Ross MT et al.(2001). The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X. Nature vol. 409, (6822) 942-943.
10.1038/35057165
Klungel OH, Heckbert SR, Longstreth WT, Furberg CD, Kaplan RC, Smith NL, Lemaitre RN, Leufkens HGM et al.(2001). Antihypertensive drug therapies and the risk of ischemic stroke. Archives of Internal Medicine vol. 161, (1) 37-43.
10.1001/archinte.161.1.37
Deloukas P(2001). Construction of transcript maps by somatic cell/radiation hybrid mapping. The human gene map. Methods Mol Biol vol. 175, 155-168.
10.1385/1-59259-235-X:155
Deloukas P(2001). Map integration. From a genetic map to a physical gene map and ultimately to the sequence map. Methods Mol Biol vol. 175, 129-142.
10.1385/1-59259-235-X:129
Heckbert SR, Kaplan RC, Weiss NS, Psaty BM, Lin D, Furberg CD, Starr JR, Anderson GD et al.(2001). Risk of recurrent coronary events in relation to use and recent initiation of postmenopausal hormone therapy. Archives of Internal Medicine vol. 161, (14) 1709-1713.
10.1001/archinte.161.14.1709
Kaplan RC, Frishman WH(2001). Systemic inflammation as a cardiovascular disease risk factor and as a potential target for drug therapy. Heart Disease vol. 3, (5) 326-332.
10.1097/00132580-200109000-00009
Kaplan RC(2001). Treatment of hypertension to prevent stroke: Translating evidence into clinical practice. Journal of Clinical Hypertension vol. 3, (3)
10.1111/j.1524-6175.2001.00447.x
Deloukas P (2000). Completing the sequence of human chromosome 20. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 67, 22-22.
Bench AJ, Nacheva EP, Hood TL, Holden JL, French L, Swanton S, Champion KM, Li J et al.(2000). Chromosome 20 deletions in myeloid malignancies: reduction of the common deleted region, generation of a PAC/BAC contig and identification of candidate genes. UK Cancer Cytogenetics Group (UKCCG). Oncogene vol. 19, (34) 3902-3913.
10.1038/sj.onc.1203728
Kaplan RC, Heckbert SR, Koepsell TD, Rosendaal FR, Psaty BM(2000). Use of calcium channel blockers and risk of hospitalized gastrointestinal tract bleeding. Archives of Internal Medicine vol. 160, (12) 1849-1855.
10.1001/archinte.160.12.1849
Ebenezer ND, Stavrides G, Tharmarajah S, El-Ashry M, Ficker LA, Deloukas P, Bhattacharya SS (2000). Positional cloning of the gene for CHED 1: A YAC/PAC and transcript map spanning the locus on 20p11.2. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. vol. 41, S539-S539.
Klungel OH, Kaplan RC, Heckbert SR, Smith NL, Lemaitre RN, Longstreth WT, Leufkens HGM, De Boer A et al.(2000). Control of blood pressure and risk of stroke among pharmacologically treated hypertensive patients. Stroke vol. 31, (2) 420-424.
10.1161/01.STR.31.2.420
Dublin S, Lydon-Rochelle M, Kaplan RC, Watts DH, Critchlow CW (2000). Maternal and neonatal outcomes after induction of labor without an identified indication. American Journal of Obstetrics and Gynecology. vol. 183, 986-994.
10.1067/mob.2000.106748
Deloukas P, French L, Meitinger T, Moschonas NK(2000). Report of the third international workshop on human chromosome 10 mapping and sequencing 1999. Cytogenet Cell Genet vol. 90, (1-2) 1-12.
10.1159/000015653
Kaplan RC, Psaty BM(1999). ACE-inhibitor therapy and nosocomial pneumonia. American Journal of Hypertension vol. 12, (11 I) 1161-1162.
10.1016/S0895-7061(99)00166-1
Malas S, Duthie S, Deloukas P, Episkopou V(1999). The isolation and high-resolution chromosomal mapping of human SOX14 and SOX21; two members of the SOX gene family related to SOX1, SOX2, and SOX3. Mamm Genome vol. 10, (9) 934-937.
10.1007/s003359901118
Psaty BM, Weiss NS, Furberg CD, Koepsell TD, Siscovick DS, Rosendaal FR, Smith NL, Heckbert SR et al.(1999). Surrogate end points, health outcomes, and the drug-approval process for the treatment of risk factors for cardiovascular disease. Journal of the American Medical Association vol. 282, (8) 786-790.
10.1001/jama.282.8.786
Mehus JG, Deloukas P, Lambeth DO(1999). NME6: a new member of the nm23/nucleoside diphosphate kinase gene family located on human chromosome 3p21.3. Hum Genet vol. 104, (6) 454-459.
10.1007/s004390050987
Kaplan RC, Psaty BM, Heckbert SR, Smith NL, Lemaitre RN(1999). Blood pressure level and incidence of myocardial infarction among patients treated for hypertension. American Journal of Public Health vol. 89, (9) 1414-1417.
10.2105/AJPH.89.9.1414
Van Tine BA, Knops JF, Butler A, Deloukas P, Shaw GM, King PH(1998). Localization of HuC (ELAVL3) to chromosome 19p13.2 by fluorescence in situ hybridization utilizing a novel tyramide labeling technique. Genomics vol. 53, (3) 296-299.
10.1006/geno.1998.5468
Deloukas P, Schuler GD, Gyapay G, Beasley EM, Soderlund C, Rodriguez-Tomé P, Hui L, Matise TC et al.(1998). A physical map of 30,000 human genes. Science vol. 282, (5389) 744-746.
10.1126/science.282.5389.744
Bentley DR, Pruitt KD, Deloukas P, Schuler GD, Ostell J(1998). Coordination of human genome sequencing via a consensus framework map. Trends Genet vol. 14, (10) 381-384.
10.1016/s0168-9525(98)01591-1
Kaplan RC, Heckbert SR, Weiss NS, Wahl PW, Smith NL, Newton KM, Psaty BM(1998). Postmenopausal estrogens and risk of myocardial infarction in diabetic women. Diabetes Care vol. 21, (7) 1117-1121.
10.2337/diacare.21.7.1117
Bench AJ, Aldred MA, Holloway TL, Champion KM, Gilbert JGR, Humphray SJ, Gwilliam R, Deloukas P et al. (1998). Transcript mapping of the region of chromosome 20q that is deleted in myeloproliferative disorders. BRITISH JOURNAL OF HAEMATOLOGY. vol. 102, 156-156.
Bench AJ, Aldred MA, Humphray SJ, Champion KM, Gilbert JG, Asimakopoulos FA, Deloukas P, Gwilliam R et al.(1998). A detailed physical and transcriptional map of the region of chromosome 20 that is deleted in myeloproliferative disorders and refinement of the common deleted region. Genomics vol. 49, (3) 351-362.
10.1006/geno.1998.5231
Kaplan RC, Psaty BM, Kriesel D, Heckbert SR, Smith NL, Gillett C, Golston AG(1998). Replacing short-acting nifedipine with alternative medications at a large health maintenance organization. American Journal of Hypertension vol. 11, (4 I) 471-477.
10.1016/S0895-7061(97)00494-9
Soderlund C, Lau T, Deloukas P(1998). Z extensions to the RHMAPPER package. Bioinformatics vol. 14, (6) 538-539.
10.1093/bioinformatics/14.6.538
Mungall AJ, Humphray SJ, Ranby SA, Edwards CA, Heathcott RW, Clee CM, Holloway E, Peck AI et al.(1997). From long range mapping to sequence-ready contigs on human chromosome 6. Mitochondrial DNA vol. 8, (3) 151-154.
10.3109/10425179709034066
Schuler GD, Boguski MS, Stewart EA, Stein LD, Gyapay G, Rice K, White RE, Rodriguez-Tomé P et al.(1996). A gene map of the human genome. Science vol. 274, (5287) 540-546.
10.1126/science.274.5287.540
Schuler GD, Boguski MS, Hudson TJ, Hui L, Ma J, Castle AB, Wu X, Silva J et al.(1996). Genome maps .7. The human transcript map. SCIENCE vol. 274, (5287) 547-558.
Schuler GD, Boguski MS, Hudson TJ, Hui L, Ma J, Castle AB, Wu X, Silva J et al.(1996). Genome maps 7. The human transcript map. Wall chart. Science vol. 274, (5287) 547-562.
10.1126/science.274.5287.540
Mungall AJ, Edwards CA, Ranby SA, Humphray SJ, Heathcott RW, Clee CM, East CL, Holloway E et al.(1996). Physical mapping of chromosome 6: a strategy for the rapid generation of sequence-ready contigs. DNA Seq vol. 7, (1) 47-49.
10.3109/10425179609015647
Héron E, Deloukas P, van Loon AP(1995). The complete exon-intron structure of the 156-kb human gene NFKB1, which encodes the p105 and p50 proteins of transcription factors NF-kappa B and I kappa B-gamma: implications for NF-kappa B-mediated signal transduction. Genomics vol. 30, (3) 493-505.
10.1006/geno.1995.1270
Deloukas P, Dauwerse JG, van Ommen GJ, van Loon AP(1994). The human NFKB3 gene encoding the p65 subunit of transcription factor NF-kappa B is located on chromosome 11q12. Genomics vol. 19, (3) 592-594.
10.1006/geno.1994.1115
Moschonas NK, Goulielmos G, Lubyova B, Manifava M, Deloukas P, Loon AP, Kapsetaki M(1993). Dinucleotide repeat polymorphism (D10S608) adjacent to the GLUD1 locus. Hum Mol Genet vol. 2, (11)
10.1093/hmg/2.11.1981-a
Deloukas P, van Loon AP(1993). Genomic organization of the gene encoding the p65 subunit of NF-kappa B: multiple variants of the p65 protein may be generated by alternative splicing. Hum Mol Genet vol. 2, (11) 1895-1900.
10.1093/hmg/2.11.1895
Deloukas P, Dauwerse JG, Moschonas NK, van Ommen GJ, van Loon AP(1993). Three human glutamate dehydrogenase genes (GLUD1, GLUDP2, and GLUDP3) are located on chromosome 10q, but are not closely physically linked. Genomics vol. 17, (3) 676-681.
10.1006/geno.1993.1389
Deloukas P, Aigner L, Kania M, van Loon AP(1992). Construction of yeast artificial chromosome (YAC) clone banks covering three genome equivalents and isolation of YACs containing the human gene encoding tumor necrosis factor receptor beta. Gene vol. 110, (2) 189-195.
10.1016/0378-1119(92)90647-8
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